PROSITE entry PS51180
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General information about the entry
| Entry name [info] | BRO1 |
| Accession [info] | PS51180 |
| Entry type [info] | MATRIX |
| Date [info] |
01-JAN-2006 CREATED;
10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51180 |
| Associated ProRule [info] | PRU00526 |
Name and characterization of the entry
| Description [info] | BRO1 domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=388; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=383; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=-1.6812770; R2=0.0047889; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=94408.0000000; R2=0.0000000; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=2314; H_SCORE=94408; N_SCORE=9.4; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=1709; H_SCORE=94408; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-41; D=-50; I=-50; B1=-300; E1=-300; MI=-105; MD=-105; IM=-105; DM=-105; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-105; BD=-105; /M: SY='P'; M= -33, -96, -10, 27, -88, -26, 33, -14, -74, -90, -82, 51, 84, -2, -81, -24, -14, -31, -95, 19; /M: SY='L'; M= -82, -89, -99, -92, 53, -98, -86, 16, -92, 62, 51, -94, 21, -89, -92, -16, -78, 11, -84, -65; /M: SY='I'; M= -84, -91, -99, -96, 40,-101, -83, 66, -93, 50, 20, -94, -97, -88, -92, -26, -79, -53, -75, 59; /M: SY='P'; M= 27, -92, 10, -77, -17, -10, -81, -82, -80, -14, -79, -1, 65, -14, -85, 33, -7, -32, 65, 24; /M: SY='I'; M= -31, -90,-100, -95, 15, -25, -92, 68, -93, 47, -55, -94, -5, -91, -94, -88, -77, 29, -86, 6; /M: SY='P'; M= -80,-102, -15, -17,-101, 4, -80, -91, 21, -97, -85, -7, 104, 43, -10, -76, -77, -30, -96, -92; /M: SY='L'; M= -83, 4, -96, -90, 56, -98, -84, -21, -21, 70, -56, -90, -97, -87, -26, -30, 23, -63, -81, -5; /I: I=-14; MI=0; MD=-29; IM=0; DM=-29; /M: SY='K'; M= -81, -97, -75, -62, -96, -88, -76, -95, 97, -95, -83, -69, 49, -61, 42, -75, -12, -92, -92, -85; /M: SY='T'; M= -10, -89, 30, 50, -93, -85, -75, -89, 35, -88, 5, 0, -80, -7, 19, -19, 64, -83,-100, -85; /M: SY='T'; M= 9, -80, -10, -76, -87, -81, -84, -79, -75, -83, -79, -65, -78, -77, -83, 26, 108, -71,-104, -84; /M: SY='S'; M= -74, 17, 19, 41, -7, -28, -1, -86, 25, -3, -80, 13, -83, -4, -72, 47, 33, -83, -97, -80; /I: I=-10; MI=0; MD=-21; IM=0; DM=-21; /M: SY='E'; M= -7, -94, 32, 54, -94, -84, 39, -30, -4, -32, -81, -2, 47, 34, -74, 17, -25, -33,-100, -84; /M: SY='V'; M= -25, -86, -98, -93, 32, -98, -93, 36, -92, 44, -57, -92, -95, -91, -93, -21, 5, 62, -90, -70; /I: I=-15; MI=0; MD=-32; IM=0; DM=-32; /M: SY='D'; M= -76, -91, 101, -57, -99, -77, 11, -98, -72, -99, -94, 34, -84, -70, -79, 54, -9, -94,-114, -85; /M: SY='W'; M= -89, -96,-104, -17, 74, -98, -92, -66, -91, 50, 8,-101, -99, -90, -91, -94, -88, -73, 131, -50; /M: SY='S'; M= 24, -86, -79, -15, -88, 4, -82, -23, 27, -30, -76, -72, -84, 37, -74, 53, 10, 28, -96, -83; /M: SY='K'; M= -4, -90, 26, 4, -91, -84, -77, -84, 59, -32, -80, -13, -9, 6, 20, -1, 46, -12, -98, -84; /M: SY='P'; M= 42, -94, -80, 14, -93, 15, 10, -19, -72, -31, -79, -79, 73, -6, 30, -20, -76, -35, -95, -87; /M: SY='L'; M= -84, -88,-102, -96, 31,-103, -88, 29, -95, 80, 19, -99,-100, -90, -93, -93, -80, -2, -85, -66; /M: SY='K'; M= -10, -87, -74, -72, -89, -29, 11, -30, 48, -37, -79, 31, -84, -10, 32, 43, 44, -28, -98, -82; /M: SY='S'; M= -30, 45, 45, 8, -10, -80, 3, -89, 17, -90, -84, 26, -85, 29, 5, 48, 7, -29,-100, -81; /M: SY='Y'; M= -85, 17, -9, -22, 57, -96, 11, -1, -86, -2, -67, -87, -5, -84, -86, -84, -19, 8, -65, 97; /M: SY='I'; M= -79, -92, -96, -92, -69,-100, -94, 90, -17, 23, -56, -88, -91, -85, -11, 4, -16, 5, -92, -75; /M: SY='S'; M= -9, -89, 24, 7, -81, -82, 38, -81, 30, 23, -74, -8, -85, -4, -22, 51, 2, -80, -94, 6; /M: SY='N'; M= 3, -89, -21, -3, -7, -81, -75, -83, 16, -32, 2, 40, 17, 26, 30, 36, 20, -29, -95, -81; /M: SY='H'; M= -72, -88, -74, -24, -83, -24, 61, 22, -7, -81, -75, 28, -84, 26, -76, 47, 57, -25, -97, 5; /M: SY='Y'; M= -85, -93, -90, -91, 52, -94, -64, -68, -85, 3, -66, -88, -98, -82, -84, 1, -11, -18, -55, 117; /I: I=-8; MI=0; MD=-17; IM=0; DM=-17; /M: SY='D'; M= -81, -98, 53, -78, 22, 32, -79, -96, -83, -95, -91, 19, -10, -12, -89, 37, -17, -95, -91, 41; D=-8; /I: I=-8; DM=-17; /M: SY='Q'; M= 15, -94, 8, 48,-100, 7, 3, -95, -67, -93, -84, -8, -83, 79, -22, -3, 23, -90, -99, -86; D=-8; /I: I=-8; DM=-17; /M: SY='D'; M= -3, -94, 55, -18, -89, -83, 33, -89, -72, -91, -84, 50, 27, 41, -27, -69, 36, -31, -99, 25; D=-8; /I: I=-8; DM=-17; /M: SY='W'; M= 27, -95, -84, -78, -91, 4, 14, -94, -71, -94, -86, -78, 56, -5, 45, 34, 1, -89, 85, -80; D=-8; /I: I=-8; DM=-17; /M: SY='S'; M= 20, -90, 19, 39, -91, -27, 41, -89, -5, -44, -84, -15, -84, -68, -23, 57, -21, -26, -99, -13; D=-8; /I: I=-8; DM=-17; /M: SY='Q'; M= 8, -91, 12, 17, -19, -84, -77, -80, -1, -44, 24, 10, -87, 46, 27, 35, -22, 8, -98, -82; D=-8; /I: I=-8; DM=-17; /M: SY='F'; M= -87, -92, -99, -97, 90,-100, -77, -62, -92, -28, -67, -93,-102, -94, -90, -87, -12, 34, -62, 86; D=-8; /I: I=-8; DM=-17; /M: SY='R'; M= 11, 10, 12, 40, -84, -85, -71, -28, 11, -87, -80, 14, -86, 44, 52, -27, -18, -85, -87, 44; /M: SY='D'; M= 6, -92, 69, 52, -92, -82, 2, -90, 6, 0, -83, 18, -83, -65, 5, 16, -73, -87,-102, -84; /M: SY='D'; M= 20, -95, 86, 54,-101, -33, 18, -97, -68, -94, -89, -63, -81, 50, -75, -69, -16, -92,-105, -85; /I: I=-11; MI=0; MD=-23; IM=0; DM=-23; /M: SY='L'; M= -32, 48, -99, -95, -4,-100, -93, 54, -94, 58, -57, -93, -97, -91, -95, -31, 15, 1, -94, -75; D=-11; /I: I=-11; DM=-23; /M: SY='K'; M= 27, -92, 21, 20, -93, -24, -79, -30, 54, -22, -81, -14, -85, 19, -15, 12, -17, -34, -97, -86; D=-11; /I: I=-11; DM=-23; /M: SY='E'; M= 18, -92, 3, 61, -92, -23, -79, -35, 27, -88, -83, -73, -82, 18, -72, 0, 32, -8, -96, -9; D=-11; /I: I=-11; DM=-23; /M: SY='L'; M= -32, -89, -99, -94, 43,-101, 37, 42, -93, 65, 6, -93, -97, -89, -91, -90, -79, 11, -86, -64; /M: SY='N'; M= -24, -90, 58, 5, -92, -81, -72, -81, 25, -86, 26, 69, -85, 19, -20, -21, 9, 11,-104, -84; /M: SY='R'; M= 7, -93, 51, -64, -94, -28, 52, -94, 35, -39, -81, 17, -86, 37, 53, -25, -14, -90,-100, -80; /M: SY='L'; M= 7, 32, -95, -90, -64, -94, -82, -56, -90, 75, 55, -6, -97, -85, -89, -84, -13, -26, -90, -2; /M: SY='R'; M= -84,-101, -79, -12, -95, -93, -71, -99, 16, -93, -82, -74, 17, -58, 112, -78, -82, -94, -93, -82; /M: SY='Q'; M= -78, -94, -13, -14, -9, -81, -69, -32, 9, -90, -80, 66, 20, 87, 21, 7, -21, -89, -95, -81; /M: SY='N'; M= 25, -89, 60, 4, -96, 0, -73, -90, -20, -93, -86, 63, -84, 24, -18, 1, 10, -29,-103, -87; /M: SY='A'; M= 69, 31, -91, -86, -12, -20, -90, 33, -86, 6, 8, -84, -89, -82, -89, 2, -73, -7, 36, -78; /M: SY='R'; M= 10, 44, -83, -79, -14, -86, -81, 9, -70, -14, -71, 35, -92, 22, 51, 3, -10, 37, -97, -79; /M: SY='N'; M= -5, 12, -11, -20, -90, 38, 9, -19, -26, -31, 6, 48, -86, -9, 21, 14, 32, -82, -99, -84; /M: SY='P'; M= 6, -92, 21, 29, -85, -13, -83, -25, -77, 13, -73, -79, 58, -4, -19, 6, -73, 34, -98, -85; /M: SY='D'; M= 27, -90, 39, -69, -91, -8, 18, -86, 28, 3, -79, 10, 32, 16, -23, 34, -71, -84, -98, -83; /M: SY='R'; M= 23, -91, 10, -6, -9, 2, 10, -26, -26, 11, -74, 31, 32, -74, 40, -74, -76, 0, -95, -80; /M: SY='D'; M= 2, 11, 61, 2, -91, 2, -77, -85, -76, 0, -82, 39, 23, -73, -83, 38, -12, -33,-103, -87; /M: SY='D'; M= 8, -91, 54, 25, -15, -83, 26, 3, 2, -35, -79, 25, -3, 19, -76, 11, -15, -6,-100, -80; /I: I=-8; MI=0; MD=-16; IM=0; DM=-16; /M: SY='H'; M= 32, -87, -17, 7, -90, -80, 53, -16, -76, -84, -79, 18, -18, -11, -81, 42, 45, 8,-103, -82; D=-8; /I: I=-8; MI=0; MD=-16; IM=0; DM=-16; /M: SY='G'; M= 5, -95, 21, -86, -89, 64, -88, -24, -88, 3, -81, -12, -93, 1, -93, -15, -82, 0, -97, -6; D=-8; /I: I=-8; DM=-16; /M: SY='L'; M= -26, 12, -24, -28, -73,-100, -90, 34, -20, 54, -61, -91, -98, -84, 28, -32, -80, 18, -97, -80; D=-8; /I: I=-8; DM=-16; /M: SY='D'; M= -28, -94, 67, 48,-100, -83, -74, -99, 30, -97, -91, -7, -83, 4, 5, 42, -21, -93,-104, -88; D=-8; /I: I=-8; DM=-16; /M: SY='Q'; M= 28, -89, -89, -80, -78, -89, 8, 17, 1, 34, 32, -82, -91, 41, -27, 6, -18, 11, -95, -78; D=-8; /I: I=-8; DM=-16; /M: SY='L'; M= -84, 6, -93, -93, 19, -98, -82, 18, -90, 75, -53, 34,-100, -87, -90, -88, -78, -15, -85, 18; /M: SY='Y'; M= -35, -90, -80, -12, 11, -90, -71, -71, 19, 16, 31, 16, -90, 41, -15, -74, 34, -11, -77, 69; /M: SY='K'; M= -31, -93, 12, 31, -93, -86, -74, -20, 59, -88, -1, 10, -83, 20, 49, 1, 19, -84, -96, -83; /M: SY='Y'; M= -89,-100, -89, -91, -37, -95, -55, -74, -83, -71, -68, -90,-101, -78, -80, -84, -83, -80, 31, 138; /M: SY='Y'; M= -2, 9, -91, -90, 45, -94, 42, -69, -86, 22, 19, -88, -98, -82, -83, -83, -81, -73, -60, 108; /M: SY='P'; M= 36, -90, 9, -74, -94, 35, 29, -34, -23, -88, 7, -10, 38, 24, -16, 33, -72, -31, -97, -85; /M: SY='Q'; M= -30, -97, -80, -65, 5, -89, 20, -4, -24, -28, 1, -75, -89, 106, -67, -72, -20, -31, -78, 63; /M: SY='L'; M= -84, -87,-102, -95, -59,-104, -87, 10, -96, 91, -47,-101,-101, -89, -93, -94, -80, -18, -89, -71; /M: SY='C'; M= -29, 72, 13, 61, -17, -38, 10, -81, 17, -16, -79, -14, -85, -69, -75, -4, 11, 8,-100, -83; /M: SY='W'; M= 27, 17, -86, -81, 36, -23, 2, -73, -80, 5, 36, -16, -91, 42, -82, 20, -21, -19, 53, 42; /M: SY='L'; M= -83, -89,-103, -96, -61,-104, -91, 56, -95, 74, 19, -99, -98, -89, -94, -93, -79, 11, 34, -71; /M: SY='E'; M= -7, -94, 42, 60, -81, -15, -74, 15, -72, -32, -77, -72, -83, 39, -77, 4, -18, -19, -88, 44; /M: SY='L'; M= 20, -88, -7, -74, 10, -15, -79, -74, 30, 31, -70, 13, -12, 26, -15, -2, 20, -26, -92, -77; /M: SY='R'; M= -81, 19, -76, -67, -95, -5, -73, -99, 76, -94, -83, 0, -87, -60, 88, -75, -79, -93, -93, -83; /M: SY='F'; M= -88, -90, -98, -16, 98,-101, 17, 38, -93, 32, -60, -93, -98, -94, -92, -90, -82, -21, -71, -50; /I: I=-5; MD=-9; /M: SY='P'; M= -29, -99, 16, -77, 2, 26, -85, -25, -82, -13, -83, 16, 99, -83, -91, -27, -77, -88, -95, -88; D=-5; /I: I=-5; MD=-9; /M: SY='M'; M= 19, -89, 33, -78, 22, -83, 11, -3, -81, -78, 39, 28, 14, -80, -86, 34, 9, 9, -98, -78; D=-5; /I: I=-5; MD=-9; /M: SY='D'; M= -29, -97, 56, 23, -8, 32, 30,-100, -26, -97, -90, 11, 26, -10, 7, 14, -77, -96,-101, -85; D=-5; /I: I=-5; MD=-9; /M: SY='C'; M= 21, 68, -20, 30, -93, -7, -84, -4, -20, -86, -82, -75, -87, 35, -9, 25, 15, -13,-101, -89; D=-5; /I: I=-5; MI=0; MD=-9; IM=0; DM=-9; /M: SY='Q'; M= -41,-110, -95, -17, 18, -15, -94,-102, -29, -41, -96, 15,-107, 34, 27, -4, -21, -39,-108, -93; D=-5; /I: I=-5; DM=-9; /M: SY='Q'; M= -92,-112, -89, 13,-112, -6, 28, -23, -16,-105, -97, -86,-101, 60, 21, 10, -12,-103,-113, -97; D=-5; /I: I=-5; DM=-9; /M: SY='M'; M= -9,-104, -21, -99, -22, -27, -98, 32, -8, 13, 51, -13,-105, -94, -98, 4, -89, -77,-107, -91; D=-5; /I: I=-5; DM=-9; /M: SY='K'; M= -8, 10, -79, 24,-105, 21, -86,-100, 50,-101, -92, 17, -11, 24, -23, -24, -83, -24,-104, -96; D=-5; /I: I=-5; DM=-9; /M: SY='V'; M= -7, -88, -97, -91, -70, -97, -92, 44, -90, 46, 30, -93, 35, -88, -93, -84, -11, 51, -95, -77; /M: SY='E'; M= -4, -93, 41, 59, 7, -85, -78, -17, -72, -45, -82, -15, 55, -9, -80, 13, 11, -28, -96, -83; /M: SY='F'; M= -90, -89,-102, -98, 118, -99, -85, -18, -94, -59, -68, -92, -12,-103, -93, -88, -10, -24, -61, 2; /M: SY='T'; M= 9, 22, -73, 30, -89, -83, 7, -80, -21, -83, 6, -70, 23, 3, -78, 16, 80, -19,-101, -84; /M: SY='W'; M= -93,-118,-119, -98, -57, -91,-116, -90, -89, -88, -90,-113, -97, -89, -93, -99,-105,-105, 180, 6; /M: SY='Y'; M= -82, -93, -83, -81, 53, -89, 18, -80, 15, -76, -74, -17, -93, -73, 40, 20, 11, -81, -65, 95; /I: I=-13; MI=0; MD=-27; IM=0; DM=-27; /M: SY='D'; M= -4, -95, 93, 3, -92, -8, -74, -91, -74, -8, -86, -7, 26, -7, -81, 3, -74, -89,-101, 2; /M: SY='A'; M= 60, -83, -14, -77, -91, 0, -84, -22, -78, -87, -81, -71, 25, -76, -85, 49, 55, -74, -98, -87; /I: I=-9; MI=0; MD=-19; IM=0; DM=-19; /M: SY='Y'; M= -98,-107,-108,-102, 39,-110, -91, -82, -98, 25, 35,-102, -12, 1, -21, -9, -16, -87, -90, 46; D=-9; /I: I=-9; DM=-19; /M: SY='S'; M= -37,-102, 25, -87, -24, 27, 0, -23, -84,-101, -96, 6, -99, -85, 23, 41, -20, -38,-110, -94; D=-9; /I: I=-9; DM=-19; /M: SY='F'; M= -32, -93, -87, -79, 59, -89, 7, -79, 17, 16, -74, -81, 43, 31, -22, 32, -2, -80, -86, -69; D=-9; /I: I=-9; DM=-19; /M: SY='S'; M= -22, -89, 12, 19, -94, 8, -78, -91, 25, -91, 16, -9, -16, -8, -74, 59, 43, -85,-100, -87; D=-9; /I: I=-9; DM=-19; /M: SY='S'; M= 21, -96, -23, -27,-103, 33, 36,-102, -83,-102, -93, -2, 12, 18, -88, 49, -17, -95,-106, -93; D=-9; /I: I=-9; DM=-19; /M: SY='N'; M= -7, -90, -11, 9, -83, -11, 2, -77, 31, 7, 2, 37, 20, -10, 1, 5, -22, 5, -94, -5; /M: SY='P'; M= -79, -95, -82, -14, 28, 7, -82, -81, 42, -14, -78, -79, 76, -74, 27, -3, -24, -5, -89, -79; /M: SY='V'; M= -30, -87, -86, -15, 13, -32, 29, 1, -25, -11, 9, -81, -89, -82, -84, -22, 48, 54, -86, 45; /M: SY='T'; M= -9, 5, -78, -72, -91, -29, -79, -26, 25, -87, -80, -70, 24, 25, 43, 47, 52, -34, -97, -84; /M: SY='Q'; M= -77, -96, -10, -64, -6, -29, 11, 4, -66, 6, -71, -72, -88, 103, 9, 25, -76, -80, -88, -7; /M: SY='H'; M= -4, 19, -22, 24, -86, -82, 73, -89, -24, -88, -80, 47, -85, 35, 19, 16, 18, -30, -97, 18; /M: SY='S'; M= -9, -84, 14, -73, -91, 1, -75, -89, -22, -41, -85, 57, -83, -70, -78, 80, 28, -84,-102, -85; /M: SY='L'; M= -83, -89,-103, -96, -60,-104, -90, 46, -95, 82, -49,-100, -99, -90, -94, -94, -79, 0, 33, -71; /M: SY='A'; M= 46, -88, -78, 8, -87, -81, 40, -16, 25, -16, -74, -74, -85, 21, 18, 29, -15, 5, -96, -80; /I: I=-11; MI=0; MD=-23; IM=0; DM=-23; /M: SY='F'; M= -88, -91, -98, -96, 105, -27, 11, -3, -92, -16, -67, -90,-100, -94, -90, -19, -83, -71, 34, 60; /M: SY='E'; M= -77, -99, -48, 116,-101, -94, -71,-102, -59, -94, -90, -74, -73, -51, -69, -74, -78, -94, -98, -91; /M: SY='K'; M= -82, -94, -77, -66, -83, -90, 45, -85, 86, 15, -73, -71, -86, 20, 38, -76, -18, -85, -89, 7; /M: SY='A'; M= 72, 11, -88, -82, 27, -28, -85, -15, -81, 10, 1, -80, -88, -79, -14, 31, -71, -69, -89, -76; /M: SY='C'; M= -28, 91, -73, -81, 12, -76, -75, -85, -77, -84, 43, 77, -91, -76, -82, 60, -17, -82,-101, -81; /M: SY='V'; M= -73, -86, -98, -94, -70,-101, -98, 54, -91, -5, 5, -91, -93, -91, -93, -81, 29, 83,-100, -77; /M: SY='L'; M= -83, -88,-102, -96, -61,-104, -89, 52, -95, 79, 39, -98, -98, -88, -93, -93, -79, -12, -90, -72; /M: SY='Y'; M= -88, -92, -94, -94, 95, -96, 4, -70, -88, -25, -68, -89,-100, -89, -86, -23, -18, -75, -55, 99; /M: SY='N'; M= -78, -86, -58, -72, -92, -73, -64, -89, -65, -46, -83, 114, -88, 35, -9, -62, 40, -89,-108, -86; /M: SY='I'; M= -83, 11,-100, -96, -61,-103, -87, 75, -93, 58, 35, -94, -96, -88, -93, -90, -26, -49, -85, 33; /M: SY='G'; M= 54, -87, -83, -86, -96, 83, -88, -92, -84, -93, -86, -71, -85, -81, -90, -3, -17, -26, -93, -92; /M: SY='A'; M= 67, 43, -86, -82, -81, -76, -85, -17, -82, -6, -73, -78, -87, -78, -86, 48, -9, 16, -94, -2; /M: SY='L'; M= 30, 19, -96, -90, -67, -93, -87, 34, -90, 61, 35, -90, -94, -86, -91, -80, 8, -3, -90, -7; /M: SY='Y'; M= -33, -92, -92, -88, 10, -96, 56, -63, -26, 60, 11, -89, -98, -81, -82, -86, -81, -69, -69, 92; /M: SY='S'; M= 23, -82, -75, -75, -87, -70, 18, -88, -75, -90, -84, -65, -82, -69, -80, 97, 29, -80, -96, 2; /M: SY='Q'; M= -74, 36, -75, -22, -91, -83, -72, -83, -23, -2, 9, -2, -85, 100, -11, 34, 27, -83, -95, -80; /M: SY='M'; M= -35, -89, -96, -90, -14, -97, 1, 51, -88, 49, 65, -89, -93, -4, -88, -20, -10, 1, -86, 25; /M: SY='A'; M= 93, -81, -85, -80, -95, 42, -87, -87, -81, -88, -81, -77, -84, -78, -87, -60, -72, -75, -93, -90; /I: I=-5; MI=0; MD=-11; IM=0; DM=-11; /M: SY='A'; M= 50, -86, -81, -20, -25, -33, -83, 3, 2, -18, -75, 17, -87, -11, -24, 36, 0, 9, -96, -83; D=-5; /I: I=-5; DM=-11; /M: SY='S'; M= 30, -89, -68, 43, -93, -78, 16, -88, 5, -88, 2, 31, -83, 38, 18, 50, -69, -27, -98, -83; /M: SY='Q'; M= 4, 1, -72, 48, -85, -86, 14, -19, -3, -29, 51, -16, -84, 74, -21, -4, -16, -36, -91, 6; /M: SY='D'; M= -26, 20, 58, -71, -87, -7, -76, -7, -74, -20, 36, 46, -18, -4, 7, 23, -15, 1,-103, -84; /M: SY='R'; M= -23, -93, -9, -13, -15, -84, -71, -90, -15, -17, -80, 57, 17, -65, 84, 14, -74, -88, -96, -81; /I: I=-10; MI=0; MD=-22; IM=0; DM=-22; /M: SY='E'; M= 6,-102, 24, 49,-101, -15, 34,-104, -14,-100, -92, -17, -90, 32, 12, -3, -29, -98,-104, -10; D=-10; /I: I=-10; MI=0; MD=-22; IM=0; DM=-22; /M: SY='T'; M= -13, 10, 23, 0, -94, -35, -82, -95, 11, -96, -90, 11, -89, -76, 8, 24, 61, -88,-104, 1; D=-10; /I: I=-10; DM=-22; /M: SY='T'; M= 15, -96, 42, 30, -97, -90, -85, -88, -17, -18, -86, -76, 17, 21, -83, -20, 48, -26,-107, -92; D=-10; /I: I=-10; DM=-22; /M: SY='E'; M= 32, 13, 64, 75, -98, -82, -75, -32, -69, -92, -88, -3, -1, -65, -77, -26, -21, -86,-103, -89; /M: SY='G'; M= 16, -90, 35, 3, -98, 71, -79, -99, -75, -98, -90, 35, -84, -74, -10, 17, -23, -92, -98, -91; /M: SY='L'; M= -33, -91,-100, -94, 9,-100, -84, 38, -92, 67, 12, -97, -11, -88, -91, -90, -80, -19, 45, 48; /M: SY='K'; M= -24, -94, -73, -1, -95, -87, -77, -90, 101, -92, -82, -68, -4, 0, -9, -73, -15, -22, -92, -84; /M: SY='R'; M= -5, -90, -19, 26, -88, -28, 19, -24, -22, -32, 7, -15, -84, 36, 49, -5, 47, -4, -98, -81; /M: SY='A'; M= 86, -80, -82, -77, -92, -67, -84, -82, -79, -86, -80, -74, -83, -74, -83, 62, -64, -21, -95, -87; /M: SY='C'; M= 17, 102, -94, -92, 31, -91, -87, 36, -89, -14, 31, -85, -95, -89, -92, -15, 8, -17, -87, 32; /M: SY='H'; M= 16, -91, 27, -19, -90, -27, 49, -88, 29, -42, -81, 29, 9, 24, 7, 25, -16, -35, -97, -10; /M: SY='Y'; M= 21, 15, -83, -83, -59, -87, 75, -28, -81, 14, 4, 23, -94, -11, -80, -77, -79, -76, 28, 93; /M: SY='F'; M= -88, -88,-102, -97, 91,-101, -84, -10, -94, 61, 5, -96,-101, -95, -92, -91, -25, -63, -71, 3; /M: SY='Q'; M= -13, 38, -76, -61, -95, -84, -71, -87, 7, -14, -75, -70, -86, 110, 2, 16, 4, -86, -93, -80; /M: SY='Q'; M= 13, 42, -13, -19, -16, -85, 2, -84, 35, 1, 7, 15, -88, 76, 32, -72, -77, -83, -93, -78; /M: SY='A'; M= 85, -79, -81, -76, -92, -67, -83, -85, -78, -87, -81, -73, -83, -73, -83, 63, 2, -73, -96, -87; /M: SY='A'; M= 85, -81, -84, -78, -22, -70, -83, -79, -77, -81, 28, -76, -84, -75, -10, 39, -9, -30, -93, -83; /M: SY='G'; M= -11, -92, -80, -30, -96, 95, -86, -99, -83, -35, -88, -69, -85, -81, -25, 0, -17, -93, -92, -92; /M: SY='C'; M= 20, 113, -98, -94, -78, -93, -96, 41, -91, -66, 43, -88, -97, -92, -95, -80, -74, 51,-103, -84; /M: SY='F'; M= -4, -88,-100, -95, 103, -97, 10, -63, -93, 27, -63, -92,-100, -95, -90, -87, -82, -17, -65, 39; /I: I=-12; MI=0; MD=-25; IM=0; DM=-25; /M: SY='E'; M= 16, -91, 28, 49, -95, -81, 4, -91, 19, -40, -82, 25, -82, 45, 10, 15, 15, -86, -99, -84; /M: SY='Y'; M= -87, -96, -90, -87, 60, -95, 59, 3, -82, -10, -67, -85, -97, 1, -18, -29, -82, -75, 45, 102; /M: SY='L'; M= -25, -89,-102, -95, -62,-102, -89, 62, -94, 71, 47, -97, -96, -88, -93, -91, -78, -18, -90, -72; /M: SY='N'; M= -3, -89, -74, -75, -83, -80, -73, 23, 23, -17, -76, 63, -88, -68, 52, 47, -69, -76, -94, -3; /M: SY='E'; M= -76, -93, 47, 86, -97, -87, -73, -93, -65, -44, -86, -13, -77, 30, -73, 2, 41, -88,-101, -87; /I: I=-13; MI=0; MD=-27; IM=0; DM=-27; /M: SY='N'; M= -31, -89, -22, -19, -89, -80, 11, -18, 19, -89, -82, 80, -87, 15, -14, 22, 37, -28,-101, -3; D=-13; /I: I=-13; DM=-27; /M: SY='F'; M= -83, -89, -94, -19, 99, -33, -84, -3, -30, -61, 7, -15, -97, -92, -88, -23, -78, 39, -70, 11; /M: SY='L'; M= -29, 19, -86, -1, -18, -93, -83, -16, -26, 60, -61, -83, -11, 4, 13, 0, 33, -31, -92, -76; /M: SY='H'; M= -80, -93, -68, -22, -89, -28, 99, -18, -13, -33, -77, 74, 38, -3, -18, 2, -16, -89,-106, -75; /M: SY='A'; M= 52, -84, 4, 14, -89, -76, -80, -16, -25, -35, 8, -9, -83, 3, -79, 50, 30, -25, -98, -84; /I: I=-6; MD=-12; /M: SY='L'; M= -99, 20, -13, -21, -16,-113,-102, -28, -33, 26, -4, -20,-114,-101,-105, -1, -95, -2,-111, -5; D=-6; /I: I=-6; MD=-12; /M: SY='E'; M=-101,-119, -22, 38, -12, -33, -97,-119, 3,-116,-109, -4, -17, -6, 15, -2, -98,-116,-117,-105; D=-6; /I: I=-6; MI=0; MD=-12; IM=0; DM=-12; /M: SY='P'; M= -95,-119, -98, -87,-113, -98,-100,-102, -94, -44, -98,-102, 113, -96,-105, -20, -88,-106,-110,-111; D=-6; /I: I=-6; DM=-12; /M: SY='S'; M= -23, 13, -92, -91,-102, -1, -94, -99, -90, -20, -94, -82, 4, -86, -26, 73, 6, -94,-111, -98; D=-6; /I: I=-6; DM=-12; /M: SY='P'; M= -12,-107, -26, -34, -98,-101, -95, -31, -89, -96, -92, -20, 31, -13, 11, 16, -2, 19,-108, 13; D=-6; /I: I=-6; MI=0; MD=-12; IM=0; DM=-12; /M: SY='D'; M= -82, -96, 112, -8, -17, -30, -74, -21, -74, -92, -92, -58, -85, -73, -82, -26, -74, -9,-112, -84; /M: SY='M'; M= -81, 6,-101, -94, 18, -99, -84, 39, -91, 60, 92, -93, -95, -86, -90, -19, -77, -21, -88, -68; /M: SY='S'; M= 5, -88, 58, -18, -95, -25, 3, -92, -71, -91, 7, 1, -83, 51, -76, 71, -14, -87,-102, -83; /M: SY='P'; M= 17, -95, -16, 52, -94, -82, -75, -93, -24, -93, -84, -74, 64, 34, 33, 28, -22, -88, -93, -5; /M: SY='E'; M= 44, -88, 45, 53, -92, -77, -73, -90, -21, -89, -4, 38, -82, -2, -75, 14, 7, -83, -97, -4; /M: SY='T'; M= -73, -82, -79, -83, 14, -86, -82, -19, -79, -26, 48, 35, -84, -80, -84, 0, 89, 22, -98, -76; /M: SY='L'; M= -79, -87, -97, -91, -3,-100, -89, 37, -90, 60, 20, -91, -95, -6, -91, -84, 26, 42, -92, -72; /M: SY='K'; M= -6, 38, -75, -25, -93, 8, 3, -92, 55, -36, -82, 15, -85, 17, 31, 44, -15, -87, -96, -84; /M: SY='A'; M= 68, 51, -90, -85, 63, -25, -87, -74, -85, -16, 3, -82, -90, -85, -88, -6, 7, -32, -84, -69; /M: SY='L'; M= -84, -88, -98, -91, -7,-100, -84, -12, -91, 82, -51, -13,-100, -5, -90, -91, -80, -2, 44, 6; /M: SY='S'; M= -13, -88, -76, 28, -78, -84, -78, 8, 18, -17, -73, -8, -86, -70, 8, 55, -18, 26, -90, 29; /M: SY='S'; M= -10, -90, 6, 0, -87, -12, 39, -18, 35, -38, 15, 42, -84, 17, -20, 44, -20, -83, -96, -8; /M: SY='L'; M= -83, -88,-102, -95, -8,-102, -85, 35, -93, 73, 66, -97, -98, -87, -91, -92, -79, 2, -86, 7; /M: SY='M'; M= -6, 59, -98, -91, 11, -92, -79, -58, -87, 30, 121, -88, -92, -82, -86, -31, -24, -21, -91, -70; /M: SY='L'; M= -83, 21, -96, -90, -63, -99, 57, -19, -91, 79, 62, -91, -97, -84, -88, -89, -18, -61, -93, -69; /M: SY='A'; M= 96, -81, -85, -79, -94, 27, -87, -86, -81, -87, -80, -78, -84, -78, -86, -60, -72, -73, -93, -90; /M: SY='Q'; M= -22, -99, -6, 61,-102, -86, -68, -92, -60, -34, -78, -70, -81, 115, -63, -69, -78, -92, -93, -82; /M: SY='A'; M= 98, 20, -85, -78, -93, -67, -87, -84, -80, -85, -79, -79, -84, -76, -85, 6, -69, -71, -94, -89; /M: SY='Q'; M= -35, -98, -72, -55,-102, -84, 58, -92, -61, -87, -75, -66, -84, 125, -61, -25, 8, -92, -93, -76; /M: SY='E'; M= -78, -96, -55, 105, -92, -94, -73, -88, -63, 3, 17, -76, -76, 0, -71, -75, -10, -86, -96, -86; /M: SY='C'; M= -29, 114, -95, -92, -76, -93, -90, -3, -89, 21, 60, -84, -96, -89, -92, -31, 35, 17,-103, -83; /M: SY='F'; M= -4, 10,-100, -96, 86, -97, -88, 39, -93, 5, -62, -92, -97, -95, -93, -85, -17, 32, -74, 23; /M: SY='W'; M= -84, 13,-104, -95, 48, -97, -96, -12, -92, 37, -65, -98, -98, -92, -93, -89, -1, 31, 129, 2; /M: SY='Q'; M= -32, -94, -76, 47, 29, -28, -75, -3, -20, 23, 3, -78, -87, 75, -9, -15, -78, -76, -84, 7; /M: SY='K'; M= -80, -94, -12, -61, -96, -31, 14, -97, 99, -95, -83, 10, -82, 21, 12, -72, -22, -93, -93, -82; /I: I=-1; MD=-3; /M: SY='A'; M= 52, 21, -90, -85, -84, -28, -88, -6, -85, 17, 12, -82, -91, -13, -88, 45, -22, 6, -98, -85; D=-1; /I: I=-1; MD=-3; /M: SY='I'; M= -80, 11, -9, -90, -74, -97, 8, 50, -90, 35, 11, -4, -95, -87, -92, 13, 4, 33,-101, -79; D=-1; /I: I=-1; MD=-3; /M: SY='N'; M= 28, -90, -81, -5, 31, -85, -80, -77, -22, 26, 25, 44, -13, -8, 5, 15, -75, -78, -92, -76; D=-1; /I: I=-1; MD=-3; /M: SY='D'; M= -26, -98, 70, 32,-104, 14, -77,-101, -20,-102, -94, 31, 41, -3, -81, 16, -75, -98,-106, -93; D=-1; /I: I=-1; MD=-3; /M: SY='G'; M= 7, -95, 36, -75,-101, 47, -83, -96, 39, -99, -91, 33, -17, -11, -77, -20, -10, -24,-103, -93; D=-1; /I: I=-1; MI=0; MD=-3; IM=0; DM=-3; /M: SY='M'; M= -83, -94, -84, -21, 5, -93, 6, -77, 52, 0, 78, -17, -91, -71, 24, -3, -10, -79, -85, 41; D=-1; /I: I=-1; DM=-3; /M: SY='K'; M= -31, 5, -79, -70, -94, -37, -79, -89, 76, -31, -2, -6, -88, 15, 32, 20, -11, -28, -97, -85; D=-1; /I: I=-1; DM=-3; /M: SY='D'; M= 27, -94, 63, -11, -85, -82, 36, -91, -77, -24, -84, 40, 16, -6, -82, 2, -75, -89, -96, 41; D=-1; /I: I=-1; DM=-3; /M: SY='S'; M= 22, -86, -84, -84, -14, 11, -86, -18, -83, -1, -79, -73, -88, -78, -87, 75, 24, -34, -98, -83; D=-1; /I: I=-1; DM=-3; /M: SY='L'; M= -82, -91, -97, -91, -69, -24, -89, 21, -8, 70, -58, -92, -14, -86, -21, 8, -79, -6, -94, -78; D=-1; /I: I=-1; DM=-3; /M: SY='I'; M= -2, -92,-101, -97, -5,-101, -98, 78, -94, 10, 33, -93, -94, -92, -97, -86, 10, 29, -95, -76; D=-1; /I: I=-1; DM=-3; /M: SY='A'; M= 81, 5, -87, -82, -94, -25, -89, -82, -83, -88, -82, -80, -2, -80, -88, 40, -70, 1, -99, -91; D=-1; /I: I=-1; DM=-3; /M: SY='K'; M= -83, -99, -78, -64,-100, -90, -76,-100, 89, -97, -85, -71, -3, 32, 59, -15, -79, -96, -94, -85; D=-1; /I: I=-1; DM=-3; /M: SY='L'; M= -24, -92, -94, 11, -68,-102, -89, 32, -92, 75, -55, -97, -5, -86, -93, -32, -81, -60, -93, -78; D=-1; /I: I=-1; DM=-3; /M: SY='A'; M= 70, 68, -87, -84, -94, 4, -88, -89, -84, -32, -84, -78, -90, -80, -89, 52, -70, -79,-100, -91; D=-1; /I: I=-1; DM=-3; /M: SY='A'; M= 50, -91, -85, -80, -80, -37, 3, -5, -27, 2, 9, 11, -4, 33, -24, 13, -75, -76, -89, 37; D=-1; /I: I=-1; DM=-3; /M: SY='Q'; M= -35, -98, -77, -65,-100, -8, -75, -96, 38, -94, -83, 0, -3, 97, -20, 14, 0, -94, 42, -83; D=-1; /I: I=-1; DM=-3; /M: SY='V'; M= 16, 39, -93, -91, -81, -38, -97, 6, -89, -27, -70, -85, -93, -90, -93, -14, 49, 68,-105, -85; D=-1; /I: I=-1; DM=-3; /M: SY='S'; M= 48, 4, -86, -83, 18, 20, -87, -83, -83, -42, -82, -77, -4, 1, -88, 55, -21, -6, -95, -82; D=-1; /I: I=-1; DM=-3; /M: SY='E'; M= 4, -94, 42, 57, -90, -22, -77, -87, -73, 1, -83, 45, -3, -70, -24, -27, -14, -34,-101, -12; D=-1; /I: I=-1; DM=-3; /M: SY='Y'; M= -9, -92, -93, -26, 61, -97, 3, -66, -90, 45, 3, -6,-100, -87, -89, -86, -24, -32, -73, 68; D=-1; /I: I=-1; DM=-3; /M: SY='Y'; M= -90,-100, -91, -93, 32, -97, 19, -78, -86, -74, -71, -90,-102, -82, -83, -17, -84, -82, -52, 127; D=-1; /I: I=-1; DM=-3; /M: SY='Q'; M= -34, 7, 29, 37,-100, -11, -77, -98, 19, -96, -89, -15, -3, 47, 4, 35, 15, -92,-102, -89; D=-1; /I: I=-1; DM=-3; /M: SY='E'; M= -6, -93, 35, 51, -98, -35, -77, -95, 22, -42, -88, -14, -83, 30, -73, 48, 5, -89,-102, -88; D=-1; /I: I=-1; DM=-3; /M: SY='C'; M= 76, 86, -93, -87, -88, -79, -93, -77, -88, -2, -77, -86, -94, -86, -92, -16, -74, 7,-101, -90; D=-1; /I: I=-1; DM=-3; /M: SY='H'; M= -36, 34, -94, -89, 26, -40, 68, -24, -89, 28, -69, -86, -99, 17, -89, -25, -12, 18, 27, 26; D=-1; /I: I=-1; DM=-3; /M: SY='K'; M= 3,-100, 38, 41,-104, -89, 13,-104, 47,-101, -93, 40, -89, -8, 23, -77, -81, -99,-107, -91; D=-1; /I: I=-1; DM=-3; /M: SY='M'; M= 14, -95, 2, -29, 41, -37, -3, -18, -87, -29, 47, -11, -95, -7, -89, 28, -19, -81, 34, 20; D=-1; /I: I=-1; MI=0; MD=-3; IM=0; DM=-3; /M: SY='M'; M= -99,-113, 7, -32, -9, -34,-102, -98,-102, -96, 66, -97, -13, -3,-106, 7, 16, -40,-119,-100; D=-1; /I: I=-1; DM=-3; /M: SY='W'; M= 3,-116, 4, -6,-110, -41,-106, -10, 0, -39,-102, -98,-109, -15, -29, -6, -21,-101, 42,-104; D=-1; /I: I=-1; DM=-3; /M: SY='E'; M= -42,-116, 5, 37,-118,-109, -99, -28, -25,-110,-106, 15,-106, 14, -97, -20, 2, -28,-126,-110; D=-1; /I: I=-1; DM=-3; /M: SY='A'; M= 47, 10, 5, -19, 3, 18, -87, -20, -84, -92, -87, 7, 11, -5, -25, -22, -24, -85, -97, -3; D=-1; /I: I=-1; DM=-3; /M: SY='Q'; M= -37,-100, -22, -19, -96, -13, -81, -25, -77, -91, -1, 42, 39, 63, -20, 3, -10, 0,-102, -10; D=-1; /I: I=-1; DM=-3; /M: SY='V'; M= -36, 11, -91, -22, -84, -6, -91, 16, -5, -17, 12, -85, -95, -84, 0, 26, 15, 33,-101, -5; D=-1; /I: I=-1; DM=-3; /M: SY='S'; M= 6, -93, -82, -18, -97, -32, 7, -91, 30, -40, -86, -75, -4, -3, -17, 51, 39, -35,-104, -89; D=-1; /I: I=-1; DM=-3; /M: SY='P'; M= -1,-103, 22, 37,-105, 16, -87, -35, 14,-102, -94, -21, 71, -77, -84, -23, -82, -96,-104, -98; D=-1; /I: I=-1; DM=-3; /M: SY='Y'; M= 1, -97, -90, -29, -15, -93, -79, -7, -85, -3, -76, 6, -98, -7, -19, 19, -19, -8, 37, 77; D=-1; /I: I=-1; DM=-3; /M: SY='I'; M= -86, 15,-106,-105, 34, 23,-104, 69,-101, -14, -69, -96,-101,-100,-103, -92, -85, 24, 35, -76; D=-1; /I: I=-1; DM=-3; /M: SY='P'; M= -89,-107, 42, 31,-109, -94, -82,-106, 26,-105, -96, -7, 49, 25, 32, -9, -84,-104,-108, -96; D=-1; /I: I=-1; DM=-3; /M: SY='K'; M= -15, -99, -23, -82, -21, -93, -88, -86, 35, 9, -83, -83, 26, -80, 20, 30, 5, -31,-100, -14; D=-1; /I: I=-1; DM=-3; /M: SY='N'; M= -16,-100, 36, 34, -22, -90, -81, -22, 22, -96, -92, 42, -93, -75, -24, 20, -79, -38,-103, 3; D=-1; /I: I=-1; DM=-3; /M: SY='W'; M= -96,-113,-119,-102, 20, -99,-110, -82, -95, 4, -83,-113,-103, -95, -97,-102,-102, -32, 163, 9; D=-1; /I: I=-1; DM=-3; /M: SY='I'; M= -16, -93, -92, -88, -14, -96, -93, 45, 12, -19, -71, -18, -10, -84, 8, 4, 20, 40,-100, -82; D=-1; /I: I=-1; DM=-3; /M: SY='H'; M= 16, -95, 3, -78, -90, -87, 62, -92, 30, -19, -84, 26, -12, -76, -14, 9, 21, -89,-101, 15; D=-1; /I: I=-1; DM=-3; /M: SY='H'; M= -24, -95, -92, -22, -7, -98, 83, 23, -89, 26, 28, -86, -96, -83, -89, -25, -1, 7, 44, -3; D=-1; /I: I=-1; DM=-3; /M: SY='M'; M= -10, 44,-101, -97, -76,-100, -95, 41, -94, 11, 68, -93, -97, -92, -96, -30, 8, 48,-102, -82; D=-1; /I: I=-1; DM=-3; /M: SY='Q'; M= -30, 1, -75, -14, -6, -85, 32, -90, -2, -89, -82, 29, -4, 69, -74, 25, 45, -87, -93, 25; D=-1; /I: I=-1; DM=-3; /M: SY='M'; M= 33, 35, -93, -26, 5, 7, -91, 16, -89, 1, 52, -87, -93, -86, -92, 3, -76, 34, -96, -80; D=-1; /I: I=-1; DM=-3; /M: SY='K'; M= -80, -96, 12, -58, -98, -87, -74, -97, 105, -95, -83, -65, -81, 31, 0, -74, -75, -93, -91, -83; /M: SY='H'; M= 23, -90, 30, -69, -85, -81, 47, -2, 30, -41, 35, 17, -86, 32, -16, 27, -71, -10, -96, -8; /M: SY='H'; M= -8, 10, -8, 1, 8, -87, 86, -82, 18, 13, 9, 9, -9, 39, -22, -21, -78, -83, -93, -1; /M: SY='H'; M= -7, -93, -87, -86, 50, -93, 93, -22, -85, 17, -64, -82, -96, -80, -82, -82, -82, -20, -69, 90; /M: SY='F'; M= -89, -93, -94, -16, 94, -98, -72, -67, -88, -11, 9, -92, -11, -89, -87, -87, -83, -25, -58, 93; /M: SY='Q'; M= 21, -89, -74, 28, -88, -5, -77, -80, 26, 0, 8, 9, -84, 41, 19, -23, 35, -26, -95, -83; /M: SY='A'; M= 78, -81, -82, -79, -87, -4, -83, -79, -80, -84, -79, -74, -84, -75, -84, 54, -7, 1, -92, 4; /M: SY='V'; M= 21, 13, -95, -91, -8, -92, -91, 32, -90, 43, 4, -13, -95, -87, -91, -16, -73, 55, -94, -75; /M: SY='A'; M= 82, 18, -83, -79, -90, 1, 16, -24, -80, -83, 0, -75, -84, -76, -85, 25, 11, -72, -96, -85; /I: I=-1; MD=-2; /M: SY='H'; M= 0, -96, -77, -19, -80, -87, 95, -86, -72, -30, -74, -72, -89, 84, -72, 4, -23, -25, -89, 52; D=-1; /I: I=-1; MI=0; MD=-2; IM=0; DM=-2; /M: SY='Y'; M= -95,-104, -97, -99, 14,-103, -65, -77, -91, -15, 16, -97,-107, -87, -88, -92, -89, -82, -55, 124; D=-1; /I: I=-1; DM=-2; /M: SY='R'; M= -32,-102, -87, -83, 43, -96, 65, -94, -69, -87, -82, 8,-100, 3, 69, -18, -86, -93, -85, 53; D=-1; /I: I=-1; DM=-2; /M: SY='M'; M= -38, -96, -87, -82, -87, -93, 59, 4, 12, -10, 66, 8, -94, 43, -79, 11, -26, 7,-104, -80; D=-1; /I: I=-1; DM=-2; /M: SY='A'; M= 61, -90, -89, -88, -98, 35, -91, -19, -88, -45, -87, -79, -91, -83, -92, 52, -74, -82,-101, -94; D=-1; /I: I=-1; DM=-2; /M: SY='L'; M= -86, -97, -11, -22, -80,-100, -87, 11, -22, 49, 8, -87, -97, 24, 21, 1, 15, -72,-100, -83; D=-1; /I: I=-1; DM=-2; /M: SY='H'; M= 29, -96, 18, -20, -92, -89, 73, -29, -81, -6, -79, -78, -94, 35, -11, 14, -80, 6,-107, -82; D=-1; /I: I=-1; DM=-2; /M: SY='C'; M= 15, 49, 30, -83, 9, -92, -87, -19, -88, 36, -74, 12, -99, 22, -91, -18, -11, -78,-101, -83; D=-1; /I: I=-1; DM=-2; /M: SY='E'; M= -36, 9, 3, 64, -91, -32, 3, -33, 2, 22, -80, -14, -91, -73, -82, 1, -82, -29,-104, -89; D=-1; /I: I=-1; DM=-2; /M: SY='E'; M= -1,-103, 41, 71,-101, -92, -78,-103, 3, -99, -93, -76, -9, 45, -75, -18, -82, -98,-101, 4; D=-1; /I: I=-1; DM=-2; /M: SY='Q'; M= 19,-111, -92, 2,-116, -34, 27, -25, -22,-110,-102, 23,-106, 33, -94, 4, -93,-103,-120,-104; D=-1; /I: I=-1; DM=-2; /M: SY='K'; M= -26, -98, 10, -74,-101, 23, -81, -99, 48, -34, -89, 24, -92, 32, 19, 15, -17, -96,-102, -91; D=-1; /I: I=-1; MI=0; MD=-2; IM=0; DM=-2; /M: SY='K'; M= -84, -99, -75, -18, -99, -90, -77, -98, 84, -35, -85, 31, -88, 47, 23, -29, -79, -95, -97, -87; D=-1; /I: I=-1; DM=-2; /M: SY='Y'; M= -88, 9, -93, -91, 41, -99, 45, 12, -88, -25, 16, -90, 6, -3, -86, -87, -84, -4, -67, 98; D=-1; /I: I=-1; DM=-2; /M: SY='G'; M= -27, -96, -84, -93,-103, 97, -90,-108, -89,-105, -95, -71, -12, -86, -96, 3, -84,-101, -95, -97; D=-1; /I: I=-1; DM=-2; /M: SY='E'; M= -38,-100, 5, 82, -96, -93, 2, -34, -72, -37, -88, 12, -12, -3, -80, -17, -25, -26, 42, -88; D=-1; /I: I=-1; DM=-2; /M: SY='A'; M= 51, 3, -79, 35, -99, -29, 7, -89, -74, -92, -85, -3, -2, 33, 11, -1, -78, -4,-102, -91; D=-1; /I: I=-1; DM=-2; /M: SY='I'; M= -84, -96,-107,-102, -72,-110,-103, 77, -96, 20, -60,-100,-100, -96, -14, -94, -80, 53,-100, -81; D=-1; /I: I=-1; DM=-2; /M: SY='A'; M= 61, 11, -88, -83, -99, 28, -89, -90, -26, -93, -87, -80, -13, 1, 8, 23, -77, -12,-100, -93; D=-1; /I: I=-1; DM=-2; /M: SY='Y'; M= -36, 17, -18, -84, 6, -96, 5, -86, -13, -14, 6, -84,-100, -76, 62, -4, -84, -86, -77, 81; D=-1; /I: I=-1; DM=-2; /M: SY='L'; M= -89, -94,-105, -99, 14, -40, -89, -16, -95, 77, -56,-102,-106, -92, -12, -97, -86, -24, -89, 5; D=-1; /I: I=-1; DM=-2; /M: SY='Q'; M= -31, -98, -21, -23,-100, -88, -77, -96, 43, -42, -85, 19, -89, 76, 32, 8, 15, -93,-100, -87; D=-1; /I: I=-1; DM=-2; /M: SY='V'; M= -32, -96, -2, 2, -20, -98, 7, 19, 23, 13, 5, -85, -13, -2, -82, -24, -25, 29, -97, -3; D=-1; /I: I=-1; DM=-2; /M: SY='A'; M= 78, -87, -87, -83, -97, -29, 16, -88, -83, -91, -85, -80, -90, -79, -21, 43, -72, -20,-101, -90; D=-1; /I: I=-1; DM=-2; /M: SY='L'; M= -12, -94, -84, 13, -83, -94, 16, -20, -20, 33, 2, 15, -13, 32, -84, -28, 8, 18,-102, -83; D=-1; /I: I=-1; DM=-2; /M: SY='Q'; M= 13, -94, -14, 16, -99, -83, 3, -93, 6, -33, -85, 29, -12, 55, -76, 37, 17, -89,-103, -89; D=-1; /I: I=-1; DM=-2; /M: SY='C'; M= 15, 46, -89, 0, -17, -93, 17, -1, 0, 20, -74, -87, -5, 13, -20, -6, -82, -31, 35, 4; D=-1; /I: I=-1; DM=-2; /M: SY='I'; M= 13, 42,-103, -98, 13,-100, -97, 47, -96, 32, 37, -96,-100, -94, -98, -87, -12, 21, -96, -78; D=-1; /I: I=-1; DM=-2; /M: SY='N'; M= -36, -95, 22, -13,-100, -30, -77, -35, 61, -99, -90, 67, -89, -10, -67, 18, -12, -93,-105, -91; D=-1; /I: I=-1; DM=-2; /M: SY='E'; M= -77, -97, -18, 72,-102, -10, -79,-101, 3, -99, -92, -4, -83, 24, -75, 42, 20, -94,-104, -92; D=-1; /I: I=-1; DM=-2; /M: SY='A'; M= 69, -88, -90, -84, -93, 7, -91, -30, -16, -12, -80, -82, -91, -7, -87, 25, -75, -7, -99, -91; D=-1; /I: I=-1; DM=-2; /M: SY='Q'; M= -31, -95, -85, -28, -20, -11, 3, -23, -18, 28, -75, -17, 18, 36, -25, 28, 23, -80, -99, -83; D=-1; /I: I=-1; DM=-2; /M: SY='K'; M= -82, -97, -16, -77, -21, -32, 16, -87, 54, 10, 9, -17, 7, -74, 2, 37, -23, -87, 32, -81; D=-1; /I: I=-1; DM=-2; /M: SY='Y'; M= -11, 9, -16, 14, -20, -32, 2, -84, 18, 10, -79, 22, -93, -11, -18, 11, -10, -35, -93, 35; D=-1; /I: I=-1; DM=-2; /M: SY='S'; M= 14, -94, -17, -79, 18, -31, -85, -89, 30, -20, -84, -78, 31, -78, 9, 38, 15, -86, -93, -4; D=-1; /I: I=-1; MI=0; MD=-2; IM=0; DM=-2; /M: SY='K'; M= -44,-123,-108,-100, -11, -17, -1,-123, 34,-120,-112,-100, -11, -96, 20, 6,-103,-119,-120,-106; D=-1; /I: I=-1; DM=-2; /M: SY='Y'; M=-107,-125, 42,-102,-104, 20,-102,-122,-108,-121,-116, -20,-118,-106,-114, -25, -30,-121, 22, 45; D=-1; /I: I=-1; DM=-2; /M: SY='V'; M= -3, 1, -1,-104, 16,-114,-107, -35,-104, -3, -90,-106,-117, -8, -16,-101, -29, 17,-111, -12; D=-1; /I: I=-1; DM=-2; /M: SY='N'; M= 11,-111, -98,-104, -98, -40, -96,-102,-100,-108,-102, 49, -14, -98,-105, 11, -92, -11, 26, 37; D=-1; /I: I=-1; DM=-2; /M: SY='D'; M= -99,-114, 35, -25,-100, -42, -97, -97, -4, -10, -97, -20, 18, -94, -32, -9, -95, -6,-113, 15; D=-1; /I: I=-1; DM=-2; /M: SY='W'; M= -3,-109, -19, 16, 3,-103, -96,-100, 2, -47, -97, -20,-104, -88, 2, -1, 0, -39, 36, -1; D=-1; /I: I=-1; DM=-2; /M: SY='V'; M= -97,-109, 30, -3, -91,-114,-102, -74,-102, 11, 14,-102, -10,-100,-106,-102, -93, 47,-115, -4; D=-1; /I: I=-1; DM=-2; /M: SY='Q'; M= -37,-110,-100, -6, 11,-111, -95, -3, -94, 3, -84, 5,-111, 35, -20, -98, -96, 5,-100, 27; D=-1; /I: I=-1; DM=-2; /M: SY='D'; M= -10,-110, 43, 41, -25, -44, -98, -9, -92,-100,-100, -89,-101, -89,-100, -25, 7, -10,-118,-101; D=-1; /I: I=-1; DM=-2; /M: SY='D'; M= -34,-108, 68, 2,-104, -33, -91, 10, -17, -21, -95, 26,-100, -87, -94, -87, -14, -92,-119,-100; D=-1; /I: I=-1; DM=-2; /M: SY='L'; M= -90, -98,-105,-100, 6,-108, -93, -19, -99, 48, -68,-101,-107, -11, -99, -23, 5, 28, -93, 38; D=-1; /I: I=-1; DM=-2; /M: SY='Q'; M= -35,-102, 17, -13,-101, -94, -87, -96, 39, -43, -91, 10, -95, 40, -16, 5, 21, -27, 34, -92; D=-1; /I: I=-1; DM=-2; /M: SY='G'; M= -16,-104, 7, -23, 31, 46, -91, -97, 3, -96, -92, -84, -14, -6, -27, -83, -19, -27, -94, 16; D=-1; /I: I=-1; DM=-2; /M: SY='F'; M= -33,-102,-106, -98, 53,-108, 27, 26, -98, 36, -70, -99,-106, 28, -97, -95, -20, -74, 35, -71; D=-1; /I: I=-1; DM=-2; /M: SY='K'; M= -15,-102, -88, 6, -9, -39, 9, -27, 56, -19, 7, -85, -96, -78, -16, -4, -24, -37, -99, -4; D=-1; /I: I=-1; DM=-2; /M: SY='D'; M= 2,-101, 64, 12,-109, -31, -86,-106, -25,-107,-101, 14, -12, -80, -27, 27, 1,-100,-116, -99; D=-1; /I: I=-1; DM=-2; /M: SY='V'; M= 3, -96, -91, 1, -94, -97, -96, -75, 3, -37, -83, -88, -97, -84, 12, 20, 26, 47,-110, -93; D=-1; /I: I=-1; DM=-2; /M: SY='I'; M= -32, 53,-112,-107, -80,-112,-109, 54,-105, 20, -68,-105,-108,-104,-107, -97, -85, 50,-109, -89; D=-1; /I: I=-1; DM=-2; /M: SY='Q'; M= -80, -98, -76, 23,-101, 4, -82, -97, 24, -37, -89, 28, -12, 38, -15, 32, 27, -94,-104, -92; D=-1; /I: I=-1; DM=-2; /M: SY='E'; M= 9, -96, 20, 52, -8, -30, 13, -8, -1, -90, -86, -75, -87, -70, 11, 33, -25, -33,-101, -85; D=-1; /I: I=-1; DM=-2; /M: SY='K'; M= 15, -95, 38, -12, -95, -88, -81, -90, 54, -15, 13, -73, -88, -11, 17, 0, 20, -86,-101, -87; D=-1; /I: I=-1; DM=-2; /M: SY='L'; M= -87, -93, -95, -29, -69,-103, 9, -63, -8, 76, -58, -93,-100, 21, -86, -90, 1, -69, -93, -2; D=-1; /I: I=-1; DM=-2; /M: SY='K'; M= 7, -94, 21, 36, -9, -86, -75, -96, 71, -94, -86, 29, -84, -9, 23, -73, -23, -91, -96, -84; D=-1; /I: I=-1; DM=-2; /M: SY='R'; M= -7, -92, -19, 13, -95, -30, 0, -91, -21, -91, -84, -2, -86, 35, 63, 41, 31, -34,-100, -84; D=-1; /I: I=-1; DM=-2; /M: SY='A'; M= 71, -84, -81, -22, -86, -76, -81, -77, -79, 23, 2, 35, -88, 13, -83, 7, -22, -73, -97, -85; D=-1; /I: I=-1; DM=-2; /M: SY='E'; M= -36, -95, -64, 77, -91, -91, -77, 8, 18, -19, -78, 42, -9, 20, -72, -76, -76, 6, -99, -87; D=-1; /I: I=-1; DM=-2; /M: SY='K'; M= -83, -96, -76, -66, -94, -90, 11, -34, 93, -38, -81, -8, -12, -62, 46, -76, -11, -89, -94, -83; D=-1; /I: I=-1; DM=-2; /M: SY='D'; M= -37, 1, 116, -7,-105, -84, -74,-103, -74,-102,-100, -57, -86, -73, -83, -74, -19, -99,-120, -90; D=-1; /I: I=-1; DM=-2; /M: SY='N'; M= -82, -88, -58, -75, -93, -73, 10, -92, 21, -25, -85, 118, -92, -69, -71, -66, -68, -94,-111, -88; D=-1; /I: I=-1; DM=-2; /M: SY='D'; M= -84, -99, 115, 6,-106, -83, -72,-104, -73,-103,-101, -6, -85, -71, -82, -6, -75,-101,-119, -90; D=-1; /I: I=-1; DM=-2; /M: SY='F'; M= -89, -93,-100, -91, 82,-100, -83, -64, -88, 45, 0, -95,-101, 30, -27, -90, -85, -19, 66, 34; D=-1; /I: I=-1; DM=-2; /M: SY='I'; M= -81, -94,-105,-101, -69,-107,-101, 96, -97, -12, 38, -96, -94, -93, -99, -92, -77, 39, -95, -76; D=-1; /I: I=-1; DM=-2; /M: SY='Y'; M= -90, -99, -89, -17, 42, -98, 20, -74, -85, -71, -70, -90,-101, -81, -83, -86, -84, -27, -52, 125; D=-1; /I: I=-1; DM=-2; /M: SY='H'; M= -86, -95, 1, -78, -77, -94, 115, -75, -21, 49, -64, -15, -4, -75, -16, -83, -83, -27,-105, -67; D=-1; /I: I=-1; DM=-2; /M: SY='Q'; M= 6, -97, 67, 39,-102, -84, 27, -99, 26, -95, -87, -16, -84, 73, -68, -20, -77, -94,-102, -85; D=-1; /I: I=-1; MI=0; MD=-2; IM=0; DM=-2; /M: SY='H'; M= -31, -97, -82, 27, -86, -92, 52, 28, -22, 0, 27, -82, 51, -75, 10, 23, -78, -31,-100, -82; D=-1; /I: I=-1; DM=-2; /M: SY='V'; M= -78, -92, -99, -17, -76,-105,-102, 49, -94, -16, -64, -98, 25, -94, -97, -89, -75, 82,-103, -83; D=-1; /I: I=-1; DM=-2; /M: SY='P'; M= -84,-108, -85, -4,-102, -90, -89, -18, -82, -97, -87, -90, 116, -6, -92, -24, -19, -27,-101, -99; D=-1; /I: I=-1; DM=-2; /M: SY='P'; M= 23, -97, 9, -73,-104, -13, -83, -99, 39,-101, -91, 12, 41, 32, -75, 39, -75, -94,-103, -94; D=-1; /I: I=-1; DM=-2; /M: SY='E'; M= -31, -98, 3, 41, -15, -96, 14, -77, -8, 14, -78, -84, 16, 2, -24, -4, -19, 23,-102, -85; D=-1; /I: I=-1; DM=-2; /M: SY='S'; M= 3, -91, -15, -15, -89, -22, -84, -6, 15, -33, -79, 13, -89, -75, 24, 38, 16, 26,-102, -86; D=-1; /I: I=-1; DM=-2; /M: SY='Q'; M= 8, -93, 26, 34,-100, -83, -80, -94, -21, -95, -88, -71, 26, 49, -78, 45, 41, -88,-103, -90; D=-1; /I: I=-1; DM=-2; /M: SY='L'; M= -27, 9,-107,-100, 20,-107, -94, -21, -98, 74, -58,-104,-107, -95, -23, -97, -86, -5, -94, -75; D=-1; /I: I=-1; DM=-2; /M: SY='P'; M= 14,-102, 31, -3,-105, -6, -86, -98, 21, -99, 13, -80, 75, -5, -82, 0, -80, -95,-104, -97; D=-1; /I: I=-1; DM=-2; /M: SY='P'; M= 12, -98, 15, -3, -97, -88, -89, -31, -20, -17, -86, -81, 65, -81, -27, 29, 17, -31,-105, -94; D=-1; /I: I=-1; DM=-2; /M: SY='I'; M= -86, -96,-107,-103, -7,-110,-104, 77,-100, 19, -62, -99,-100, -99,-102, -93, 7, 38, -99, -79; D=-1; /I: I=-1; MI=0; MD=-2; IM=0; DM=-2; /M: SY='K'; M= -9,-101, 32, 1,-102, -32, -87, -31, 59, -96, -90, -12, 12, -6, -72, -20, -19, -3,-106, -94; D=-1; /I: I=-1; DM=-2; /M: SY='P'; M= -16,-103, -85, -23,-104, 18, -88,-100, 41, -48, -92, 7, 64, -79, 19, -80, 8, -97,-103, -97; D=-1; /I: I=-1; DM=-2; /M: SY='M'; M= 41, -93, -29, -90, -83, -94, -93, -68, 17, 35, 56, -93, -99, -87, -87, -85, -82, 23,-102, -86; D=-1; /I: I=-1; MI=0; MD=-2; IM=0; DM=-2; /M: SY='D'; M= -79, -1, 54, -18, -95, -29, -82, -86, -78, -18, 7, -16, 26, 35, -24, 37, 11, -9,-107, -89; D=-1; /I: I=-1; DM=-2; /M: SY='M'; M= 34, -90, -99, -92, -77, -6, -86, -24, -91, 33, 100, -91, -19, -85, -91, -29, -80, -22, -97, -80; D=-1; /I: I=-1; DM=-2; /M: SY='V'; M= 21, -90, -97, -93, -82, 3,-100, 12, -20, -29, -70, -90, -96, -91, -93, -15, -22, 75,-104, -86; D=-1; /I: I=-1; DM=-2; /M: SY='K'; M= -17, -98, -10, -66,-101, -90, -80, -96, 91, -97, -87, -16, -7, 27, -5, -77, -17, -38, -97, -88; D=-1; /I: I=-1; DM=-2; /M: SY='P'; M= 35, 43, -89, -82, -95, -84, -91, -30, -16, -35, -84, -85, 78, -84, -90, 34, -22, -7,-102, -94; D=-1; /I: I=-1; DM=-2; /M: SY='I'; M= -85, -97, -18, -88, -80, -99, 46, 66, -34, 6, -68, -11, 24, -86, -27, -27, 33, -25,-102, -81; D=-1; /I: I=-1; DM=-2; /M: SY='P'; M= -40, -96, -89, -28, -86, -95, 17, -25, -6, 22, -73, -88, 75, -85, -88, -27, 31, 24,-102, -87; D=-1; /I: I=-1; DM=-2; /M: SY='W'; M= -87,-100, -12, -87, 9, -98, -93, 21, -26, 23, 9, -93, 63, -13, -29, -29, -83, 9, 73, -77; D=-1; /I: I=-1; DM=-2; /M: SY='Q'; M= -10, -99, 37, 35,-100, -35, -78, -94, -69, -35, -87, 29, 29, 46, 33, -8, -79, -32,-104, -91; D=-1; /I: I=-1; DM=-2; /M: SY='E'; M= 20, -95, 36, 48, -98, -88, -82, -88, 32, -41, -86, -16, -10, 12, -74, -27, 5, -2,-104, -91; D=-1; /I: I=-1; DM=-2; /M: SY='I'; M= -84, -95, -10, -87, -17,-100, -90, 39, -18, 35, 32, -18, 14, 13, -89, -31, -18, 25, -98, -80; D=-1; /I: I=-1; DM=-2; /M: SY='Y'; M= 20,-113,-108, -6, -23,-111,-101, -96, -34, -20, -1,-108,-114,-101,-105, -98, 2, -25,-102, 48; D=-1; /I: I=-1; DM=-2; /M: SY='Q'; M= -20,-122, -30, 4,-122, 16, -4,-118, 12, -52, -2, -99, -17, 21, -97, -99,-106,-116,-122,-112; D=-1; /I: I=-1; MI=0; MD=-2; IM=0; DM=-2; /M: SY='K'; M= -38,-103, -91, -86,-101, -32, -92, -5, 32, -93, 7, 8, 18, 12, 3, 9, 1, 6,-109, -96; D=-1; /I: I=-1; DM=-2; /M: SY='K'; M= 12,-101, -18, 14, -22, -13, 2, -30, 25, -95, -90, -83, -17, -80, 18, 3, 3, -10,-106, -92; D=-1; /I: I=-1; DM=-2; /M: SY='K'; M= -32,-100, 3, 11, -88, -99, 1, -1, 25, 4, 13, -18, 9, -6, -82, -85, 9, 9,-103, -11; D=-1; /I: I=-1; DM=-2; /M: SY='K'; M= -86, -99, 10, -81, -23, -31, -88, -8, 33, 7, -80, 8, -96, 16, 2, -2, 17, -2,-104, -87; D=-1; /I: I=-1; DM=-2; /M: SY='G'; M= -84, 48, 25, -24, 10, 49, -86,-100, 16, -96, 7, -15, -97, -85, -87, -7, -86, -98, -94, 32; D=-1; /I: I=-1; DM=-2; /M: SY='P'; M= -86,-102, 8, 15, -98, -32, -86, -7, -79, -20, -86, 24, 46, 19, 7, -6, 23, -31,-108, -94; D=-1; /I: I=-1; DM=-2; /M: SY='D'; M= 10, -94, 85, -1, -96, -33, 53, -21, -27, -92, -86, 28, 28, -72, -79, -26, -19, -34,-108, -84; /M: SY='L'; M= -6, -87,-100, -94, 8, -24, -89, 34, -94, 74, 13, -95, -97, -89, -93, -88, -79, 1, -88, -70; /M: SY='F'; M= -89, -89, -97, -18, 112, -98, -80, -66, -92, 8, -66, -92,-100, -95, -90, -17, -82, -71, -61, 42; /M: SY='R'; M= 35, -90, -78, -19, -92, -22, -78, -84, 42, -44, -79, -15, 25, 13, 48, 12, 4, -8, -95, -85; /M: SY='N'; M= -6, -92, 6, 19, -91, 24, -73, -92, 53, -93, -85, 57, -85, -65, 35, -13, -74, -30, -94, 5; /M: SY='L'; M= -83, -88,-102, -96, 20,-104, -90, 47, -95, 74, 12, -98, -99, -91, -94, -92, -78, 20, -87, -68; /M: SY='V'; M= -21, 41, -98, -93, -70, -98, -95, 30, -92, 38, -58, -92, -96, -91, -93, -17, -17, 75, -99, -78; /M: SY='P'; M= -82, 0, -85, -75, -97, -86, -87, -25, -79, -39, -83, -88, 122, -83, -26, -24, -10, -88, -97, -96; /M: SY='M'; M= 4, 22, -94, -88, 25, -92, -81, 37, -84, -2, 71, -86, -93, -6, -17, 7, -74, 26, -81, 48; /I: E1=0; IE=-105; DE=-105; /M: SY='A'; M= 56, -87, 24, 29, -90, -6, 43, -84, -75, -12, -79, 11, -84, -2, -80, 20, -16, -30, -99, -83; /M: SY='V'; M= -4, -86, -9, -88, -12, -94, -94, 37, -88, -11, -62, -87, -93, -15, -91, 7, -69, 82, -98, -77; /M: SY='H'; M= -82, -94, -76, 18, 16, -91, 100, -2, -13, -11, 38, -13, -88, 41, -73, -76, 6, -30, -89, 35; /M: SY='E'; M= -79, -97, 20, 83, -91, -91, 37, -35, -62, -36, -81, -7, -81, 50, 19, -73, -13, -35, -96, -1; /M: SY='S'; M= 56, -84, -81, -76, -4, -75, -78, -78, 11, -19, -76, -13, -86, -1, -21, 59, -67, -7, -87, 26; /M: SY='M'; M= 29, 39, -77, 35, -82, -4, -79, -75, -76, 26, 41, 0, -87, 4, -25, 28, -14, -31, -96, -82; /M: SY='S'; M= 10, -85, -4, -69, -92, -74, -76, -85, -12, -44, -81, -5, -83, 60, -74, 80, 26, -26, -98, -83; /M: SY='A'; M= 47, -86, -90, -83, -15, -85, -86, 40, 20, 31, 6, -83, -89, -79, -81, 7, -22, 0, -89, -5; /M: SY='Y'; M= -29, -96, -90, -91, 33, -93, -60, -12, -84, -68, 7, -88, -99, -80, -82, -20, -81, -75, -50, 127; /M: SY='S'; M= 11, -85, 27, 21, -94, -73, -73, -92, -69, -94, -87, 56, -83, -66, 5, 75, 9, -85,-103, -86; /M: SY='E'; M= -27, -97, 12, 99, -97, -27, -72, -26, -62, -35, -84, -73, -77, 49, -70, -73, -78, -88, -97, -88; /M: SY='E'; M= -81, 16, -66, 74, -90, -93, 41, -91, 8, -13, 18, -12, -84, -59, 72, -77, -80, -88, -97, -81; /M: SY='K'; M= -78, 13, 10, -6, -97, -87, -74, -91, 83, -91, -81, -67, -83, 73, 6, -18, -11, -28, -94, -83; /M: SY='D'; M= 63, -87, 76, 4, -97, -75, -78, -92, 7, -92, -87, -66, -83, -70, -15, 17, -19, -83,-102, -87; /M: SY='E'; M= -75, -92, -10, 54, -94, -85, -74, -18, 52, -88, -81, 2, -81, 48, 4, 27, 24, -25, -97, -84; /I: E1=0; IE=-105; DE=-105; /M: SY='Y'; M= -25, -90, -97, -93, 16, -98, -78, 38, -91, 58, 11, -93, -97, -86, -89, -18, -78, -13, -74, 74; /M: SY='V'; M= -4, -85, -99, -92, -1, -97, -93, -11, -92, 54, -56, -94, -97, -90, -92, -17, -72, 75, -94, -74; /M: SY='R'; M= -80, -95, 0, 25, -93, -86, -69, -95, -8, -29, -82, 45, -88, 0, 93, 8, -76, -91, -97, -82; /M: SY='Q'; M= 32, -90, 31, 37, -96, 3, -74, -92, 4, -90, 14, 31, -83, 43, 11, 9, -15, -86, -98, -86; /M: SY='E'; M= -17, 10, -68, 70, -84, -23, 47, -20, -18, -10, 46, -75, -83, -2, 26, 3, -77, -81, -93, 2; /M: SY='V'; M= -30, -89, -10, -17, 33, -24, -86, 45, -17, -30, 16, 2, -90, 4, -84, 4, -10, 49, -91, -72; /I: I=-14; MI=0; MD=-29; IM=0; DM=-29; /M: SY='E'; M= 17, -92, 48, 60, -98, -2, -76, -93, -6, -94, -89, 36, -83, -67, -77, 21, -14, -23,-104, -90; D=-14; /I: I=-14; DM=-29; /M: SY='P'; M= -2, -97, -13, 42, -94, -87, 12, -12, 25, -38, -80, -75, 68, 29, 40, -8, -76, -85, -95, -85; /M: SY='I'; M= -77, -88, -95, -90, -9, -97, 8, 54, -86, 33, 44, -87, -92, -85, -11, 5, 9, 46, -94, -72; /M: SY='E'; M= -26, -95, 52, 80, -98, -21, -72, -95, 15, -93, -88, 4, -80, 1, 16, -19, -75, -25,-100, -88; /M: SY='S'; M= -23, 29, -6, 27, -85, -82, -78, -75, -73, 5, -76, 37, -86, -3, -7, 50, 35, 16,-101, -83; /M: SY='A'; M= 58, 19, -89, -82, -74, -20, -81, -69, -16, 42, 54, -82, -90, 6, -82, 3, -74, -69, -88, 12; /M: SY='N'; M= -77, -87, 61, -17, -94, -19, -69, -91, -70, -95, -87, 95, -84, -71, -78, -62, 63, -88,-111, -88; /M: SY='W'; M= -76, -94, -16, 38, -89, 34, -78, -13, 46, -37, 8, 21, -83, 31, -69, -21, 16, -85, 65, -81; /M: SY='E'; M= -78, -94, -69, 71, -82, -93, 25, -20, 24, 34, 12, -77, -83, 47, -69, -17, -77, -19, -94, -79; /M: SY='M'; M= 0, -88, -96, -90, -61, -17, -77, -16, -18, 59, 87, -90, -94, -81, -85, -85, -79, -20, -81, 53; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 62 in 62 different sequences |
| Number of true positive hits | 62 in 62 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | PS_Langendijk_Genevaux |
| Feature key [info] | DOMAIN |
| Feature description [info] | BRO1 |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
62 sequences
ALIX_DICDI (Q8T7K0), ALXA_CAEEL (P34552), BRO1_ARATH (F4HXZ1), BRO1_ASPFU (Q4X0Z5), BRO1_CANAL (Q5AJC1), BRO1_CANGA (Q6FJG8), BRO1_CRYNB (P0CM45), BRO1_CRYNJ (P0CM44), BRO1_DEBHA (Q6BRL3), BRO1_EMENI (C8V212), BRO1_EREGS (Q74ZJ6), BRO1_GIBZE (Q4IBS9), BRO1_KLULA (Q6CM12), BRO1_NEUCR (Q7SAN9), BRO1_SCHPO (O13783), BRO1_USTMA (Q4PHA8), BRO1_YARLI (Q6CGJ5), BRO1_YEAST (P48582), BROX_CAEEL (Q22885), BROX_DANRE (A3KQV2), BROX_HUMAN (Q5VW32), BROX_MOUSE (Q8K2Q7), BROX_PONAB (Q5RDD7), BROX_RAT(Q4V8K5), BROX_XENTR (A4IIL4), PALA_ASPOR (Q5KU05), PALA_CANAL (Q9UW12), PALA_CANGA (Q6FKK0), PALA_CRYNB (P0CM47), PALA_CRYNJ (P0CM46), PALA_DEBHA (Q6BLT2), PALA_EMENI (P79020), PALA_EREGS (Q756C5), PALA_KLULA (Q6CU63), PALA_NEUCR (Q7S532), PALA_PYRO7 (Q51NJ3), PALA_SCHPO (Q09807), PALA_YARLI (Q8WZL4), PALA_YEAST (Q12033), PALC_CRYNB (P0CM49), PALC_CRYNJ (P0CM48), PALC_EMENI (Q9P905), PALC_NEUCR (Q7SEM8), PALC_PYRO7 (Q524Z5), PALC_YARLI (Q6C1E4), PDC6I_HUMAN (Q8WUM4), PDC6I_MOUSE (Q9WU78), PDC6I_RAT (Q9QZA2), PDC6I_XENLA (Q9W6C5), PTN23_HUMAN (Q9H3S7), PTN23_MOUSE (Q6PB44), PTN23_RAT (O88902), RHN2A_XENLA (Q6DJJ6), RHN2B_XENLA (Q63ZR5), RHN2P_HUMAN (A8MT19), RHPN1_HUMAN (Q8TCX5), RHPN1_MOUSE (Q61085), RHPN2_BOVIN (A4FUC9), RHPN2_CANLF (Q8HXG3), RHPN2_DANRE (Q6TNR1), RHPN2_HUMAN (Q8IUC4), RHPN2_MOUSE (Q8BWR8)» more
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| PDB [Detailed view] |
32 PDB
1ZB1; 2OEV; 2OEW; 2R02; 2R03; 2R05; 2XS1; 2XS8; 3C3O; 3C3Q; 3C3R; 3R9M; 3RAU; 3ULY; 3UM0; 3UM1; 3UM2; 3UM3; 3ZXP; 5CRU; 5CRV; 5LM1; 5LM2; 5MJY; 5MJZ; 5MK0; 5MK1; 5MK2; 5MK3; 5V3R; 5WA1; 6KP3 » more |