ProRule PRU00526
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00526 |
| Accession | PRU00526 |
| Dates | 23-JAN-2006 (Created)
21-NOV-2019 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51180; BRO1 |
Name | BRO1 domain |
| Function | The BRO1 domain of fungal and mammalian proteins is involved in protein targeting to the lysosome or vacuole by binding multivesicular body components (ESCRT-III proteins) like Snf7 and can thus function to target BRO1 domain-containing proteins to endosomes. |
| Scope(s) |
Eukaryota |
| Example(s) | Q6PB44 (PTN23_MOUSE); |
Propagated annotation
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Features
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| From: PS51180 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | entry | exit | /note="BRO1 #" | |||||||||
Additional information
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| Size range | 280-465 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [62] All [ 62 ]
- Retrieve set of proteins with 3D structure for this domain