PROSITE entry PS51206

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS51206
Entry name [info]	SF3_HELICASE_1
Accession [info]	PS51206
Entry type [info]	MATRIX
Date [info]	01-MAY-2006 CREATED; 01-OCT-2013 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51206
Associated ProRule [info]	PRU00551; PRU50000

Name and characterization of the entry

Description [info]

Superfamily 3 helicase of DNA viruses domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=151;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=146;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=-1.8566823; R2=0.0044754; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=2762; N_SCORE=10.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=1868; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-15; D=-20; I=-20; B1=-700; E1=-700; MI=-105; MD=-105; IM=-105; DM=-105;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-105; BD=-105;
/M: SY='E';  M= -34, -22,  47,  53, -51, -37, -37,   7, -12, -35, -41,  21,  -8,   9, -38,  -2, -21,  16, -63, -33;
/M: SY='M';  M= -33, -55,  -9,  18,  -4, -29, -36,  -5,  10,   6,  37,  29,  31,  21,  -9, -11, -37, -21,   7,   8;
/M: SY='W';  M= -20, -55,  14, -15,  38, -55, -31,  31, -21, -12, -10, -14,   7, -14,  30, -43, -31,  19,  50, -12;
/M: SY='I';  M= -12, -32,  15,  15, -23, -38,   3,  32,   6,   1,  11,  -6, -42,   8,  -2,  -6,  13,  -8, -54,  -4;
/M: SY='F';  M=   1, -49,   0, -23,  35, -38, -31, -14, -37,  23,   5, -18, -16, -19, -20,  -7,  10,  21,  -8,  30;
/M: SY='F';  M= -30,  -7, -59, -34,  63,   1, -49,  32, -54,  38,   8, -53, -58, -53, -54, -40, -41,   5,  -5,  -5;
/M: SY='W';  M= -37, -14, -46,  -6,  15, -45,  19,  -4, -15,  23,  15, -43, -52,  62,   0, -22, -30, -18,  70,  17;
/M: SY='Q';  M=   4, -14,   8,  32, -34, -32,   5,   1,   5, -32, -14,  16, -46,  42,  14,  -4,  -5, -18,   1,  -2;
/M: SY='I';  M=  24, -13, -29, -49,  37, -52, -26,  41, -27,  13,  31, -30, -54, -19, -24, -34, -31,  11,   1,  11;
/M: SY='L';  M= -16,  15, -62, -56,  29, -44, -49,  33, -54,  51,  21, -56, -59, -51, -42, -39, -33,  10,  23,   6;
/I:         I=-3; MD=-18;
/M: SY='G';  M=   7,  14, -41, -13,   9,  48,  -9, -39,  36, -43, -29, -10, -48,  11, -13,   6, -35, -49, -51, -15; D=-3;
/I:         I=-3; MD=-18;
/M: SY='W';  M= -16,  19,  -7, -24, -29, -15,   0, -34, -21,  -2,  32, -12, -26,  10, -18,  10,   1, -17,  62,  59; D=-3;
/I:         I=-3; MI=0; MD=-18; IM=0; DM=-18;
/M: SY='W';  M=  -7,  34, -62, -57,  52, -46, -29,  21, -54,  33,  25, -54, -59, -53, -55,  -7, -33,  -4,  57, -24; D=-3;
/I:         I=-3; DM=-18;
/M: SY='L';  M= -28, -50, -27, -50,   6, -47, -43,  17, -49,  50,  -8,  15, -57, -26, -50, -27,  11,  11, -48,  27; D=-3;
/I:         I=-3; DM=-18;
/M: SY='H';  M=  -5, -53, -39, -13, -36,  18,  40, -31,  30, -23, -17, -29,  13,  -8,  22,   1,  31, -32, -56, -18; D=-3;
/I:         I=-3; DM=-18;
/M: SY='G';  M=  -8, -27,  -4, -18, -55,  56, -17, -57,   6, -39, -28,  55, -33,  11,  -4,   0, -25, -54, -57, -27;
/I:         I=-6; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='T';  M= -32,   1, -31, -43,  -1, -26,  -9,  21, -14, -21, -32,  15, -15, -29,  13, -12,  51,  23, -25,  19;
/I:         I=-4; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='P';  M= -21, -57,   5,  -8, -29,  11,  -3, -41,  10, -50, -33, -16,  73, -19,  12,  16,   8, -50, -13, -15;
/M: SY='K';  M= -27, -56,  -3,  25,   1, -51,  -2, -28,  67,  -7, -38, -24, -46,  -4,   7, -39, -31, -31,  56,   2;
/M: SY='Q';  M= -25, -28, -19,  15, -58, -26,  43, -44,  51, -53, -42,  -8, -27,  62,  44, -18, -39, -54, -56, -40;
/M: SY='N';  M=  -2,  24, -37, -37, -18, -42, -17,  -3,  33, -21,  12,  55, -51, -22,  22,   0, -17,  15, -21, -41;
/M: SY='C';  M=   9,  78, -53, -52,  25, -19, -47,  16, -49,  15,  16, -16, -55, -49, -52, -16,  20,  -7, -12,  13;
/M: SY='I';  M= -18, -52, -60, -54,  41, -60, -52,  47, -53,  34,   7, -54,   2, -35, -54, -41,  -8,  18,  42,  -1;
/M: SY='W';  M= -22, -16, -60, -18,  54, -60, -53,  33, -52,  30,  13, -43, -57, -51, -53, -37, -36,  28,  72, -21;
/M: SY='F';  M= -18, -26, -36, -55,  57, -60, -49,  29, -54,  46,  27, -56, -32, -52, -53, -51, -41,   2,  43,   3;
/M: SY='Y';  M= -39,   6, -35, -32,  22, -34,  34, -12,  10, -23, -18, -29, -53, -22, -21, -17,  23,   6,  12,  80;
/M: SY='G';  M= -23, -55, -42, -24, -61,  94, -49, -67, -47, -64, -53, -29, -47, -44, -45, -22, -46, -50, -53, -56;
/M: SY='P';  M=  -8, -58,   6,  13, -56, -12,  -4, -15, -19, -41, -21,   3,  85, -29, -23,  -1,   5, -31, -60, -51;
/M: SY='G';  M=  19, -53, -43, -19, -56,  65, -48, -22, -26, -53, -45, -35,  48, -42, -23, -15,   5, -15, -55, -53;
/M: SY='N';  M=  11, -30,  37, -31, -57,  23, -19, -56,   3, -57, -48,  61, -47, -12,  22,  16,  -6, -51, -63, -48;
/M: SY='N';  M= -20,   8,   0, -36, -51, -26, -34, -46, -33, -52, -45,  74, -45, -34, -41,  32,  65, -32, -69, -47;
/M: SY='G';  M= -23, -55, -43, -55, -62,  96, -50, -69, -48, -65, -54, -29, -47, -46, -56, -28, -47, -62, -52, -57;
/M: SY='K';  M= -41, -56, -34, -20, -58, -48, -37, -58, 100, -57, -45, -27, -42, -18,  -2, -36, -36, -53, -51, -44;
/M: SY='S';  M= -23, -44, -36, -39, -53,  27, -41, -51, -37, -54, -47, -24, -42, -32, -43,  80,  46, -43, -61, -46;
/M: SY='T';  M= -30, -13, -42, -44, -36, -38, -38,  -4, -22,  -4,  23,  12, -46, -33, -45,  -1,  71,  29, -23,  10;
/M: SY='F';  M= -38, -49, -61, -57,  79, -61, -47,  23, -54,  37,  -4, -54, -59, -56, -53, -48,   8,   0, -33,  15;
/M: SY='C';  M=  34,  49, -41, -41, -22, -22, -47,  17,  -9,  19,   4, -21, -51,  33, -43, -32,   4,  -5,  23, -40;
/M: SY='M';  M=  -1, -51,  23,  12, -35, -27, -15, -43,  20, -28,  58,  52, -46,  20,  -4, -17,  -1, -43, -56,   0;
/M: SY='S';  M=  21, -46, -50, -47, -14, -27, -31,  21, -35,  33,  -4, -25, -51, -42, -48,  33,   6,  21, -55, -38;
/M: SY='L';  M= -15, -50, -63, -57,  16, -63, -52,  51, -55,  57,  18, -57, -58, -51, -55, -51, -33,  15, -49, -31;
/M: SY='M';  M=   9, -10, -44,  -8, -40, -23, -23,  28,  13,  11,  30, -19, -49,   5,  23,   4,  10, -16, -54, -27;
/M: SY='H';  M=   8, -52,  -1,   6, -51,  -8,  42, -52,  36, -31, -11,  38, -46,  24,  15,   9, -13, -49, -57, -11;
/M: SY='L';  M=  -4, -48, -59, -54,  47, -57, -47,  19, -41,  49,  38, -35, -57, -50, -51, -30, -18,  17, -44, -14;
/M: SY='L';  M= -14,  24, -60, -55,  33, -47, -12,  14, -54,  53,  16, -35, -60, -51, -53, -49, -39,  29, -47,  -1;
/M: SY='G';  M= -30, -56, -21, -32, -36,  80,   0, -63,  -3, -60, -50,  -5,  17,   1, -25, -24, -33, -59, -52, -18;
/M: SY='G';  M= -17, -14,  40,   0,  -4,  43, -39, -29, -13, -21,  -4,  11, -11,   0,  -7,   5, -18, -23, -56, -24;
/I:         I=-4; MD=-21;
/M: SY='Y';  M= -29, -34,  -3,  -3, -11, -41,   4, -53, -20, -25,  -6, -14, -67,  -3, -39, -34, -54, -33, -45,  69; D=-4;
/I:         I=-4; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='N';  M=   3, -16,  -1, -26, -38,  35,   7, -39,  25, -40, -44,  52,  -8, -22,   5,  -7,   2, -16, -59, -34;
/M: SY='C';  M=   2,  52, -38, -33, -28, -38,   4,  14, -10, -30,  20, -14, -15, -12, -45,  -2,  11,  50, -59,  -1;
/M: SY='I';  M=  22, -48, -30, -26, -33, -30, -51,  45, -49,  25,   7, -48, -37, -46, -52, -12,   2,  35, -55, -14;
/M: SY='S';  M=  -3, -30,   0, -24, -34, -22, -36, -23, -35, -42, -27,  50,  -9, -16, -41,  70,  17, -43, -63, -45;
/I:         I=-3; MD=-17;
/M: SY='F';  M=  -6, -36, -34, -27,  49, -33, -25,  -1, -25,   9,   1, -24,   6, -50, -20, -29, -20,  -7, -44,  28; D=-3;
/I:         I=-3; MI=0; MD=-17; IM=0; DM=-17;
/M: SY='W';  M=  17, -50, -21, -18,   2, -41,   8,  11, -24, -25,  -7,  -7,  31,   1, -31,  -9,  27,  24,  45, -22;
/M: SY='N';  M=   0, -49,   0, -11, -44,   4, -23, -23, -31,  11,  30,  69,  -2, -25, -18,  -5,   3, -36, -60, -19;
/M: SY='N';  M=  -9, -33,  29,  28, -54, -24,   2, -33,   9, -39,  -3,  41, -12,  17,  -1,  40, -26, -48, -61, -28;
/M: SY='K';  M=  -9, -36, -11,  30,  10,  -9,   4, -50,  43, -34, -22,  12, -45,   7,  24,  17, -14, -32, -53, -27;
/I:         I=-3; MD=-17;
/M: SY='S';  M= -20, -51,  13, -41, -17,  -3, -23, -39, -22,  18, -39,  19, -39, -37, -20,  59, -24, -38, -62, -44; D=-3;
/I:         I=-3; MI=0; MD=-17; IM=0; DM=-17;
/M: SY='H';  M= -20, -54, -30,   5, -39, -17,  63, -37,   8, -52, -42,  51, -13,  36,  44,  -1,  -4, -52, -61, -39;
/M: SY='F';  M= -31, -52, -49, -26,  90,  -7,  33, -37, -34, -31, -35,   3,  28, -49, -25, -11, -26, -33, -33,  -5;
/M: SY='W';  M= -11, -62,  11,  32, -22, -10,  -8, -34,   2, -51, -28, -13,  52, -12,  -7, -34, -28, -29, 106, -24;
/M: SY='L';  M= -25, -48, -55, -49,  40, -46, -45,  -5, -28,  57,  10, -23, -31, -31,  -3, -28,  17, -15, -46, -28;
/M: SY='Q';  M=  30, -25,   1,  13, -56,  18, -18, -26, -32, -45, -22,  30, -35,  49, -26,  30, -11, -44, -58, -47;
/M: SY='P';  M= -16, -11,  31,   8, -39, -11, -40,  -9,  -5, -29,   7,  -5,  58,   1,  18,  -5,  -9,  -7, -59, -37;
/I:         I=-4; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='L';  M=   4,  29, -59, -53, -26, -24, -23,  12, -45,  64,   5, -55, -59, -33, -52, -47, -40,   7,  -4, -20;
/M: SY='H';  M=  16, -15, -30,  12,   2,  -6,  21,  18,  -9, -16, -21, -20, -14,  -3,   7, -17,   7,   8, -50,  14;
/M: SY='G';  M= -26, -56,  55,  15, -60,  63,  14, -63, -22, -42, -52,  11, -32, -20, -19, -20, -35, -59, -61, -50;
/M: SY='K';  M=  35,  17, -40, -29, -31, -38, -41, -38,  65, -47, -40, -33, -46,  17,  14,  -7, -14,  -3, -53, -29;
/M: SY='R';  M= -35, -53, -43, -35,   8, -40, -37, -39,  36,  14,  10,  -7, -36, -19,  63,  -3,   6, -21, -51, -17;
/M: SY='L';  M=   6,   7, -60, -41,   9, -57, -53,  31, -52,  40,  26, -55, -57, -50, -53, -35, -29,  40,  38, -25;
/M: SY='V';  M=  19,  14, -50, -51, -10,   0, -51,  29, -48,  -9,  10,  22, -54, -48, -52, -27, -26,  55, -59, -32;
/M: SY='W';  M=  -2,  -2, -59, -53,  14, -57, -53,  36, -50,  29,  21, -38, -42, -49, -27, -25,  -8,  36,  62, -13;
/M: SY='W';  M=  20,  36, -28, -50,  19,  11, -51,  18, -49,  14,  17, -38, -38, -47, -52,  -3, -15,  12,  62, -33;
/M: SY='D';  M= -19, -54,  76,  38, -59, -23, -13, -34, -23, -56, -52,  -3,   5, -29, -40,  34,  -8, -38, -68, -48;
/M: SY='E';  M= -42, -60,  75,  80, -63, -50, -32, -63, -19, -48, -54, -25, -39,  -5, -34, -35, -38, -57, -67, -50;
/M: SY='V';  M=  29, -13, -49, -45, -24,  -5, -50,  21, -45,  -4,  -4, -15,  28, -10, -50,  -6,  13,  38, -58, -43;
/M: SY='T';  M= -22, -51,  16,  12, -32,   9, -39, -25,  38, -35,  -5,  11,   8,   6, -16,  -4,  46, -43, -58, -45;
/M: SY='E';  M=  -5, -54,  13,  28, -31,   6,   8,  -8,  11, -26,  15,   6,  21,   1,  -8,  -7, -16, -15, -24,  13;
/M: SY='G';  M=   2, -17,  20, -22,  -3,  40, -21, -43, -13, -50, -44,  18,   2,  11, -23,   0,  23, -23,   2,  13;
/I:         I=-3; MD=-17;
/M: SY='C';  M= -17,  74,  -9, -19, -10,  -2, -21, -17,  -9, -40, -26, -15, -23, -17,  18,  11, -14, -26, -66, -50; D=-3;
/I:         I=-3; MI=0; MD=-17; IM=0; DM=-17;
/M: SY='Y';  M= -14, -55, -14,   1, -12,   3, -10, -20,  22, -20, -20, -16, -50,   3,  27, -25,  -2, -16,  -7,  70;
/M: SY='I';  M= -38, -16, -10, -13,  27, -23, -47,  44, -23,  14,  30,   7, -53, -19, -32, -43,  -1,  18,  40, -21;
/M: SY='D';  M=   4, -51,  70,  -7, -23, -29, -39, -14, -17, -25, -17,  16, -48, -26,  -6,   3,  -9,  22, -65, -44;
/M: SY='N';  M= -21, -37,  35,  49, -57,   5, -34, -43, -22, -53, -36,  52, -42,  13, -32,  -3,  31, -28, -64, -49;
/I:         I=-5; MD=-27;
/M: SY='S';  M=  10, -77, -45, -51, -76, -27, -70, -71, -33, -22, -66, -35, -35, -17, -69,  16, -59, -57, -84, -41; D=-5;
/I:         I=-5; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='Y';  M= -23, -24,   9, -30,  -2, -17, -11,  -6,  -3, -10, -14,  49, -43,   7,   6, -13,  17, -14, -45,  50;
/M: SY='F';  M=  -4, -49, -61, -56,  45, -59, -50,  35, -54,  43,  36, -37, -58, -51, -53, -48, -38,  28,  -3, -17;
/M: SY='K';  M= -43, -57, -35, -18, -23, -50, -34, -43,  80, -53, -24,   7, -46,  -4,  60, -36, -38, -45, -52, -41;
/M: SY='N';  M=  18, -13,  16, -30, -53, -24, -16, -34,  22, -23, -27,  50, -47,  34,  -4,  31,  -8, -39, -24, -45;
/M: SY='L';  M=  14, -49, -57, -52,   2, -26,   8,  34, -39,  45,  38, -51, -55, -46, -50, -38, -33,  12, -47,  16;
/M: SY='T';  M= -23,  16, -50, -48,  -7, -54, -49, -12, -46,  43,  -1, -42, -50, -46, -50, -11,  64,  21, -28, -37;
/M: SY='G';  M= -26, -52,  55,   1, -59,  60, -42, -58, -39, -58, -52, -17, -44, -37, -47,  15,  37, -52, -62, -51;
/M: SY='G';  M= -30, -54, -22,  -2, -59,  83, -25, -60, -42, -59, -50,  19, -26, -23, -37, -22,  -8, -25, -56, -53;
/M: SY='D';  M= -27, -18,  75,  25, -36, -41,  -8, -35, -12, -55, -50,  44, -45,  10, -37,  14,  -8, -52, -64,  -1;
/I:         I=-4; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='P';  M=   2, -22, -14, -12, -28, -48, -26, -11,  24, -16,  -8, -29,  55,   1,   1, -18,  35,  -9,  -7,   2;
/M: SY='I';  M= -32, -13, -60, -56, -19, -63, -56,  59, -50,  14,  21, -33, -41, -51, -16, -47, -19,  58, -56, -20;
/M: SY='S';  M= -21,  35,   1,  -6, -23, -31,  10, -26,   7, -28,  -5,  30, -35, -15,  27,  42,  18, -30, -60, -24;
/M: SY='I';  M=  33, -31, -56, -51,  -8, -19, -53,  44, -47,  22,  -1, -49, -53, -46,  -8, -24, -25,  36, -54, -38;
/M: SY='D';  M= -31, -59,  70,  50, -57, -27, -32, -59, -15, -49, -51,   1, -10,  -7,  41, -19, -38, -45, -62, -11;
/M: SY='C';  M=  -8,  50, -26, -30,  16, -43,   4, -19,  23, -16, -19, -39,  -9,  25,  49, -29, -30,   4, -49,  10;
/M: SY='K';  M= -24, -22, -38, -26, -49, -40, -19, -45,  86, -12,  34,  -6, -21,  -6, -11, -37, -36, -34, -17, -22;
/M: SY='H';  M= -29,   6, -38, -23,   2,  36,  93, -55, -35, -42, -18,  11, -51, -33,  17, -15, -43, -54, -48,  46;
/M: SY='K';  M= -36, -56, -35,   3, -52, -13, -35, -39,  67, -24, -27,   1, -46,  42,  39, -11, -28, -22, -52, -21;
/M: SY='D';  M=  13, -51,  60,   1, -43,  -7, -18, -54,  -3, -55, -30,  46, -12,   6, -15,   8,  16, -49, -65, -47;
/M: SY='P';  M=   8, -54, -27, -18,  18, -23, -19, -25,  15,  -7, -19, -40,  68,  -2, -19,  17,  -3, -34, -14, -24;
/M: SY='F';  M= -26, -18, -38, -36,  59, -57, -15,  22, -13,  -1,  -3, -29, -55, -26,   4, -40,   8,  28,  -4,  32;
/M: SY='Q';  M= -21, -30,  20,  42, -53, -45, -15, -27, -28, -29, -41,   1,  -5,  63, -26,  23,  27, -27, -58, -15;
/M: SY='F';  M= -16, -51, -53, -48,  58, -28, -22,  39, -46,   5,  -1, -22, -38,  24, -32, -24,   6,   6, -39,  25;
/M: SY='K';  M= -21, -53, -10,   4, -13, -39, -13,  10,  45, -25, -28,  -6, -13,  14,  27, -34,  27,   5, -54, -18;
/M: SY='P';  M= -27,  56, -48, -36,  42, -32, -18, -11, -36,  -5, -11,   8,  74, -25, -35, -15, -38, -34,  11,  -2;
/M: SY='P';  M= -20,  17,  -6, -15, -13, -38,  -5, -26, -11, -41, -10, -21,  70,   6,   0,  -8,  34, -20, -51,  24;
/I:         I=-5; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='P';  M=   9, -28, -88, -68, -57, -75, -91, -88,  73, -41, -27, -83, 174, -74, -26, -47,  18, -46, -23, -97;
/M: SY='L';  M= -68, -17,-106, -94,  15,   0, -96,  17,  37,  91,  26, -92, -80, -36, -84, -85,  20,  47,-103, -70;
/M: SY='I';  M= -85,-103,-121,-110,  10,-125,  -7, 111,-106,  79,  57, -76, -64, -45,-107,-100, -48,  61,  76, -37;
/M: SY='I';  M= -55, -39,-126,-116,  11,-127,-110, 129,-109,  63,  89,-111,-112,-103,-111, -84, -73,  76,-105, -65;
/I:         I=-6; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='T';  M=  43,  -4, -20, -64, -67, -58, -90, -28, -82, -22, -51, -13, -68, -56, -93,  56, 128, -32,-120, -17; D=-6;
/I:         I=-6; DM=-29;
/M: SY='T';  M= -21,  73, -81, -85, -70,  38, -88, -55, -80, -84,  69, -59, -88, -76, -92, 101, 127, -42,-122, -89;
/M: SY='N';  M= -54, -33, -30, -72,-110, -59, -45,-106, -55,-122, -96, 227,-104, -58, -71, -46, -51, -84,-149,-101;
/M: SY='H';  M=  -8, -53, -19,  40, -23,  -1,  68,  11, -21, -30, -27,  27, -32, -20, -39, -33,  12,  -9, -55,  17;
/M: SY='N';  M= -37, -53,  37, -15,  -5, -48, -28, -14,  17,  20,  11,  43,   4, -12,   3, -21, -36, -24, -51,  24;
/M: SY='P';  M= -20, -61, -38, -41, -26, -51, -38,  19, -45,  -7,  10, -52,  99, -46, -54, -32, -37,   2,   6, -27;
/M: SY='M';  M= -14,  14, -32,   8, -17, -35,   9,  -5,  23,  -1,  27,  14,  -1, -20,  21, -21,  13,   8, -56, -19;
/M: SY='I';  M= -10, -52, -33, -15,  32, -22, -36,  40, -11, -16,   6, -20,  23, -26, -13, -12,  -6,  28,  10, -25;
/I:         I=-3; MD=-16;
/M: SY='D';  M= -31, -59,  32,   7, -11, -12, -22, -24,  26, -43, -12,  16,  -3, -24,  23, -24, -31,   5, -63, -36; D=-3;
/I:         I=-3; MI=0; MD=-16; IM=0; DM=-16;
/M: SY='D';  M=  -8, -51,  51,  28, -65,  10, -25, -29, -14, -60, -55,  29, -29, -16, -45,  -7, -14, -32, -72, -56; D=-3;
/I:         I=-3; DM=-16;
/M: SY='H';  M= -22, -41,  -2,  -5, -24, -18,  57, -36,  22, -52, -18,  20, -14,   7,  24,   0,   8, -24, -18, -29; D=-3;
/I:         I=-3; DM=-16;
/M: SY='D';  M=  -4, -55,  56, -32, -24, -16, -41, -44, -15, -29, -47, -31, -50,   2, -35,  24,  28, -40,  54,  21; D=-3;
/I:         I=-3; DM=-16;
/M: SY='Q';  M= -27, -55,   6,   6,  -5,  15,  12, -31,  31, -26,   6,  22,  -1,  37,  19,  -7, -26, -37, -53, -14;
/M: SY='Y';  M=  38, -51, -44, -44,  -4,  45, -39, -48, -43, -47, -42, -24,  28, -25, -47,  -2,  12, -43, -40,  54;
/M: SY='L';  M= -38, -50, -58, -44,  32, -61, -14,  42, -53,  48,  10, -39, -56, -50, -53, -38,  11,  16,  16, -11;
/M: SY='W';  M= -24, -48, -26,   6,  -5, -34,  42, -46,  12, -15,   3,  -6, -50,  21,  17,   1, -42, -33, 108,  23;
/M: SY='R';  M=  -5, -54,   6,   5, -55, -44, -10, -44, -15, -53, -44,  10, -34,  -3,  78,  34, -19, -34, -59, -44;
/M: SY='R';  M= -46, -62, -42, -30, -54, -56, -31, -61,   7, -54, -43, -35, -54, -19, 106, -40, -40, -55, -14, -41;
/M: SY='M';  M= -26, -51, -61, -44,  36, -61, -50,  46, -49,  30,  53, -54, -56, -23, -13, -49, -30,  25,  47, -26;
/I:         I=-3; MI=0; MD=-13; IM=0; DM=-13;
/M: SY='M';  M= -14, -17, -49, -41,   2, -54,   1,   4,  10,  13,  34, -35, -14,   8,  33, -33,   7,  28, -14,  -4;
/M: SY='V';  M= -25,  27, -34, -32, -10, -41, -30,  42, -10,  20, -11, -13, -18,  11, -41, -35, -23,  45, -56, -30;
/M: SY='F';  M= -36, -51, -60, -27,  61, -62, -53,  58, -39,  14,  -5, -54, -56, -53, -54, -27, -38,  31, -41,  -3;
/M: SY='P';  M= -32, -21,  18,  25, -52, -46,  11, -52,   2, -51, -46,  22,  78, -19,  -7, -13,  11, -44, -57,   8;
/M: SY='F';  M= -51, -50, -42, -58, 103, -61, -45, -19, -30,   8,  13, -54, -62, -60, -51, -51, -32, -21,   2,  14;
/M: SY='P';  M= -33, -52,  19,  20, -51, -45,  -4, -43,  21, -18,   0,  38,  46, -26,  -9,  -3,  30, -10, -62, -46;
/M: SY='H';  M=   8,  -6,   0,   2, -34, -44,  64, -28,  18, -46, -39,  42,  -7, -22,  25, -10, -10,   8, -63, -31;
/M: SY='K';  M= -27, -53, -20, -13, -32, -48,   5, -15,  51, -36, -38, -11,  21,  33,  11,   8,  21,   5, -55, -16;
/M: SY='F';  M= -13,  31, -44, -39,  76, -59, -22,  32, -33,   7,  -8, -52, -28, -22, -51, -47, -40,  13,  -2,   5;
/M: SY='P';  M= -17, -41,  10,   7, -29, -13, -18, -40,  -1, -29, -43, -11,  81,   0, -23,  -4,   7, -28, -54,   2;
/M: SY='P';  M= -16, -35,  13,  19,  16,   6, -19, -15,   1,   5,  -8,   6,  40,  -1, -28, -10,  -7, -26, -52, -20;
/M: SY='D';  M=   8, -53,  59,  20, -55, -15,   0, -47,  13, -39, -47,  26, -10, -11,   1,  11,  -4, -37, -27, -25;
/M: SY='E';  M= -23, -42,  30,  36,  11, -10, -22, -39,  31, -19, -21,   4,   7,  10,   2,   9, -14, -40, -55, -40;
/M: SY='D';  M= -12, -30,  36,   3, -24,  15, -30, -19,  16, -50, -30,  27,  -9,   6,  28,   8,  -4, -22, -58, -26;
/M: SY='D';  M= -21, -21,  48,   7, -27,  20, -40,   3,  17,   3, -38,  20, -48, -23, -26, -27,  -5, -14,   9, -18;
/M: SY='P';  M= -12, -54,  -3,   7,   1, -29, -42,  15,  28, -21, -23,  13,  40, -18, -10,  -9,   8, -12,  35, -17;
/M: SY='P';  M=  -9, -26,  29,  12, -53, -27,  -1, -28,   8, -20, -43,  32,  56,  14,  -1, -16,   4, -44, -12, -24;
/M: SY='L';  M=   4,  -4, -27,  -5,  -9, -26, -43,  18,  10,  30, -10,   5,   5,   3, -27,  -8, -17,   1, -52, -12;
/I:         E1=0; IE=-105; DE=-105;

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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.

Total number of hits	143 in 143 different sequences
Number of true positive hits	143 in 143 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	3
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	97.95 %

Comments [info]

Taxonomic range [info]	Bacteriophages, Eukaryotic viruses
Maximum number of repetitions [info]	1
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	N_Hulo
Feature key [info]	DOMAIN
Feature description [info]	SF3 helicase
Version [info]	4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

143 sequences

D5_FOWPN(P21969), H962R_ASFB7 (Q65162), H962R_ASFK5 (P0C9X2),

H962R_ASFM2 (Q8V9U4), H962R_ASFP4 (P0C9X3), H962R_ASFWA (P0C9X1), 
LT_BFPYV(P13894), LT_POVBA(P14999), LT_POVBG(P0DOJ4), 
LT_POVBK(P03071), LT_POVBO(P24851), LT_POVHA(P03075), 
LT_POVJC(P03072), LT_POVK3(P0DOI7), LT_POVK6(P0DOI6), 
LT_POVKI(P0DOI5), LT_POVLY(P04008), LT_POVM1(P0DOJ6), 
LT_POVM3(P0DOJ5), LT_POVMA(P03073), LT_POVMC(P12905), 
LT_POVMK(P24597), LT_POVS1(Q3L6L5), LT_POVSM(A8Y984), 
LT_POVWU(A5HBG1), LT_SV40 (P03070), NS1_AADNV   (Q90185), 
NS1_ADVG(P24030), NS1_AEDEV   (P27454), NS1_DSDNV   (O71153), 
NS1_FPV (P06431), NS1_FPV19   (P24842), NS1_HBOC1   (D0EZM8), 
NS1_HBOC2   (B9UYK5), NS1_HBOC3   (C5IY48), NS1_HBOC4   (C5IY43), 
NS1_JDNVP   (Q90054), NS1_MEVA(P27438), NS1_MUMIM   (P07300), 
NS1_MUMIP   (P03134), NS1_PAVBP   (P07296), NS1_PAVCN   (P12929), 
NS1_PAVHH   (P03133), NS1_PAVHU   (P07298), NS1_PAVHV   (Q9PZT1), 
NS1_PAVL3   (P36311), NS1_PAVPK   (P52502), NS1_PAVPN   (P18547), 
O22R_FRG3G  (Q6GZV3), PG117_MONPV (A0A7H0DN89), PG117_VACCC (P21010), 
PG117_VACCW (P04305), PG117_VAR67 (P0DST7), PG117_VARV  (P0DST8), 
PRIM_BPP4   (P10277), REP40_AAV2S (Q89269), REP52_AAV2S (Q89270), 
REP68_AAV2S (P03132), REP78_AAV2S (Q89268), V13_SPTNK   (B4YNF3), 
VE1_BPV1(P03116), VE1_BPV2(P11298), VE1_BPV3(Q8BDD7), 
VE1_BPV4(P08344), VE1_BPV5(Q705G8), VE1_BPV6(Q705F4), 
VE1_COPV6   (Q89536), VE1_CRPVK   (P03112), VE1_FPVL(P06455), 
VE1_HPV03   (P36719), VE1_HPV04   (Q07846), VE1_HPV05   (P06920), 
VE1_HPV07   (Q05133), VE1_HPV08   (P06420), VE1_HPV09   (Q05111), 
VE1_HPV1(P03111), VE1_HPV10   (P36720), VE1_HPV11   (P04014), 
VE1_HPV12   (Q05134), VE1_HPV13   (Q02261), VE1_HPV14   (P36721), 
VE1_HPV15   (Q05135), VE1_HPV16   (P03114), VE1_HPV17   (Q02512), 
VE1_HPV18   (P06789), VE1_HPV19   (Q02048), VE1_HPV20   (P50758), 
VE1_HPV21   (P50759), VE1_HPV22   (P50760), VE1_HPV23   (P50761), 
VE1_HPV24   (P50762), VE1_HPV25   (Q02049), VE1_HPV26   (P36722), 
VE1_HPV27   (P36723), VE1_HPV28   (P50763), VE1_HPV29   (P50764), 
VE1_HPV2A   (P25481), VE1_HPV30   (Q05112), VE1_HPV31   (P17382), 
VE1_HPV32   (P36724), VE1_HPV33   (P06421), VE1_HPV34   (P36725), 
VE1_HPV35   (P27220), VE1_HPV36   (P50808), VE1_HPV37   (Q80902), 
VE1_HPV38   (Q80909), VE1_HPV39   (P24829), VE1_HPV40   (P36727), 
VE1_HPV41   (P27551), VE1_HPV42   (P27221), VE1_HPV44   (Q80915), 
VE1_HPV45   (P36728), VE1_HPV47   (P22419), VE1_HPV48   (Q80922), 
VE1_HPV49   (P36729), VE1_HPV51   (P26544), VE1_HPV52   (P36730), 
VE1_HPV54   (Q81020), VE1_HPV57   (P22153), VE1_HPV58   (P26543), 
VE1_HPV59   (Q81966), VE1_HPV5B   (P26542), VE1_HPV60   (Q80943), 
VE1_HPV61   (Q80950), VE1_HPV63   (Q07847), VE1_HPV65   (Q07848), 
VE1_HPV66   (Q80957), VE1_HPV69   (Q9JH49), VE1_HPV6A   (Q84293), 
VE1_HPV6B   (P03113), VE1_HPV70   (P50765), VE1_HPV72   (Q81999), 
VE1_HPV73   (Q82007), VE1_HPVR7   (O40619), VE1_MMPV1   (P22154), 
VE1_MNPVA   (Q84356), VE1_OVPVD   (P03117), VE1_PAPVE   (P11328), 
VE1_PCPV1   (Q02262), VE1_PCPVC   (P81174), VF184_IIV3  (Q196T9), 
VF184_IIV6  (O55768), YL207_MIMIV (Q5UQ22)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

3 sequences

POL_BPNNR   (M5AAG8), VU94_HHV6H  (P0DTO4), VU94_HHV6Z  (P0DTO3)

PDB
[Detailed view]

39 PDB

1N25; 1S9H; 1SVL; 1SVM; 1SVO; 1TUE; 1U0J; 2GXA; 2H1L; 2V9P; 4E2I; 4GDF;
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