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PROSITE entry PS51214


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General information about the entry

Entry name [info] IBB
Accession [info] PS51214
Entry type [info] MATRIX
Date [info] 01-JUN-2006 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51214
Associated ProRule [info] PRU00561

Name and characterization of the entry

Description [info] IBB domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=64;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=59;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2827017; R2=0.0051970; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=7636.2465820; R2=3.1300449; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1197; H_SCORE=11383; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=812; H_SCORE=10178; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-18; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='S';  M=-21, 21,-10, -6, -3, 13,-38,-38, 13,  4, -5,-23,-47,-29,-28, 61,  4,-38,-56,-44;
/M: SY='F';  M=-14,-49,-23,-50, 78, 21,-41,-28,-15,  2,  1,-34,-20,-48,-48, 15, -7,-31,-32, -8;
/M: SY='S';  M= 21,-36,-26,  5,-50,-32,-22,-33,-30,-21,-35, -4,-42,-27,-37, 74,-11,  7,-60,-42;
/M: SY='V';  M=  6,-36,-53,-54,-35, 17,-55,  7,-49, 21, 40,-46,-57,-47,-52, 10,-27, 55,-57,-47;
/M: SY='S';  M=-26,-43, 10,-20, 22,-43,-37,-27,-34, 21, 43, 11,-42,-33,-11, 58,-10,-31,-50,-35;
/M: SY='M';  M= -4,-47, 15, -2,-42,-33, 24,-28,  9,-25, 75,-26,-50, 39, -2, 26,-27, -7,-53,-18;
/M: SY='M';  M=  4,-46, 35, 33,-51,-15,-34,-34,-28,-36, 49,  8,-47, -4,-23, 39,  9, -6,-60,-51;
/M: SY='M';  M= 13,-43, 20,-14,-16,-50, 21, -6,-41, 28, 75, -9, 13,-36,-45,-22, -9,-22,-52,-24;
/M: SY='N';  M=  5,-12, 16, 12,-31,-42,-31,-27,-13,-23, 39, 49, 25,-25, 19, 12,  3,-38,-61,-49;
/M: SY='S';  M=-14,-46, -2,  8,-24, -3, -1,-38,-30,-26,-13, 35, 31,-12,-23, 52, 18,-32,-61,-47;
/M: SY='P';  M=  6,-48,-20, -5,-60,  0,-35,-33, 16,-48, -8,  3, 43,  0, 32, 26, 24,-32,-63,-53;
/M: SY='N';  M= 24,-46, -6, -2, 10,  8,-34,-28, 12,-12,-25, 25,  1,-17, -5, 19,  1,-37,-52, -8;
/M: SY='K';  M= 26,-46, 16, -2,-46, -5,-37, -1, 26,  0, 17,  1,-49,-12, 16, -8,-14, -7,-58,-32;
/M: SY='P';  M= -6,-51, 18, 15,-56,-46, 13,-32,-17,-30, 29,  5, 70, -1,-15,  7, 18,-37,-66,-50;
/M: SY='H';  M= -2,-56, 24, 42,-53, -6, 68,-26, -8,-40, 15, 37,-29,-12,-21,  0,-28,-32,-59,-38;
/M: SY='P';  M= -9,-52, -5, 16, -1, -9, 37,-18,-20,-24,-38,  1, 50, -7,  3, -4, -1, -5,-49, 19;
/M: SY='R';  M=-46,-68,-42,-27,-61,-57,  7,-58, 20,-47, 10,-26,-56,-10,101,-36,-39,-54,-57,-48;
/M: SY='L';  M=-21,-46,-49,-37,-30,-48,-38, 10, 13, 43, 40,-41,-57, 24, 36, -4,-34,-20,-49, -5;
/M: SY='K';  M=  6,-28,-14, 11,-60,-19,  1,-40, 41,-45,-28, 29,-44, 26,  4, 35, 17,-43,-61,-49;
/M: SY='Q';  M= -2,-43,  6,-11,-51,-17,-25,-15,  1,-33,  9, 40,-49, 56, 33, 19,-12,-40,-56,-13;
/M: SY='Y';  M=-52,-61,-61,-54, 73,-49, 29,-34,-47,-29,-31,-48,-69,-46,  3,-52,-50,-39, -1,100;
/M: SY='K';  M=-36,-64,-11,-15,-67,-46,-30,-55, 92,-53,-11,-12,-42, -7, 22,-14,-33,-53,-62,-51;
/I:         I=-14; MD=-37;
/M: SY='N';  M= -4, 10,-12,-35,-27, -7,-26,-59,  5,-62,-52, 81,-53,-31,-23, 22, -5,-54,-63,-20; D=-14;
/I:         I=-14; MI=0; MD=-37; IM=0; DM=-37;
/M: SY='K';  M=-27,-61,-15,-16, -3,  6,-35,-35, 60,-29,-41, 23,-54,-24, -5,-29,-28, -5,-54,  4; D=-14;
/I:         I=-14; DM=-37;
/M: SY='G';  M= 12,-48, 11,-34,-38, 43,-31,-42, 19,-34,-42, -6,-49,-11, -5, 13,  7,-14,-45, 34;
/M: SY='K';  M=-21,-50,-41,-33, 26,-51,-36, -5, 52,  2, -6, -9,-52,-25, 26, 13,-14,  9,-47, -7;
/M: SY='D';  M= -6,-55, 75,  1,-26,-40,-32,-30,  8,-35,-46, 39,-48, -6,-24, 17, -2,-33,-65,-53;
/M: SY='A';  M= 36,  9,-42,-20,  7, -3, -4,-28,-37,  9, -4,-37, 27, 10,-43, 14, 14,-11,-55,-39;
/M: SY='E';  M=-13,-61, 61, 63,-64,-46,-27,-55, -8,-47,-47, 15,-46, 28,-29,-13, 12,-42,-64,-55;
/M: SY='E';  M=-22,-63, 35, 74,-63,-39,-25,-31,  5,-39,-43, -5,-46, 45,-24,-18,  2,-47,-61,-53;
/M: SY='M';  M=-11,-43,-44,-22,-36, 18,-43,-19,-20, 31, 71,-38, 20, -6,-21, 17,-11,-25,-55,-47;
/M: SY='R';  M=-13,-66,-34, 19,-64,-54,-25,-63, 12,-53,-43,-26,-53, -9, 98,-33,-38,-54,-58,-51;
/M: SY='R';  M=-45,-69,-21,  5,-63,-56,-25,-61, 19,-50, -7,-25,-54, 16, 97,-34,-39,-55,-58,-51;
/M: SY='R';  M=-43,-68,-38,-22,-63,-54, 16,-60, 47,-51,-11,-25,-52, 18, 91,-34,-38,-55,-58,-47;
/M: SY='R';  M=-46,-69,-43,-27,-63,-58,-25,-61, 12,-49, -7,-26,-56,-10,104,-36,-39,-55,-57,-51;
/I:         I=-26; MD=-65;
/M: SY='E';  M=-41,-63,  6, 68,-56,-55, 36,  8, -6,-46,-41, 24,-51, -7,  5,-31, -2,-13,-61,-46; D=-26;
/I:         I=-26; MD=-65;
/M: SY='E';  M=-22,-69, 49, 74,-19,-53,-31,-61,-25,-62,-54,  0,-51,-13,-36,-29,  3,-50,-64,-54; D=-26;
/I:         I=-26; MD=-65;
/M: SY='Q';  M=-21, -3,  0, 24,-35,-48, 13, -3,-35, -4,-30, 21,-59, 39,-40,-24,-30, 31,-63,-48; D=-26;
/I:         I=-26; MI=-65; IM=-65; DM=-65;
/M: SY='Q';  M=-24,  5,-31,  5,-26,  9,-35,-27,-29,  6, 25, 15,-51, 51,-33, 13, 34, -3,-56,-46;
/M: SY='V';  M=-18,-34,-66,-62,-28,-68,-65, 37,-57, 35, -7,-62,-64,-56,-59,-32,-29, 71,-57,-43;
/M: SY='E';  M=-36, -2,  2, 81,-66,-35,-21,-40,-13,-56,-43,-23,-46, 65,-22,-13,-24,-42,-60,-51;
/M: SY='L';  M=-45,-40,-67,-64, -9,-75,-59, 60,-24, 61,  1,-64,-68,-54,-21,-59,-38,  2,-52,-40;
/M: SY='R';  M=-45,-70,-40,-22,-65,-56,-23,-64,  6,-52,-41,-25,-55, 42,100,-34,-39,-57,-58,-50;
/M: SY='K';  M=-35,-65,-29, -2,-69,-46,-29,-58, 92,-56,-43,-22,-42,  7, 22,-10,-33,-55,-62,-51;
/M: SY='Q';  M= 33, -9, -3,  2,-61,-34,-24,-50, -8,-45,-40, 58,-46, 64,-25,  9, -1,-37,-62,-50;
/M: SY='K';  M=-26,-63,-16,-16,-65,-21, 25,-35, 80,-53,-42,-16,-44, 23, 33,-11,-34,-51,-61,-46;
/M: SY='R';  M=-43,-67,-40,-25,-64,-32,-27,-55, 46,-51,-42,-26,-53,-10, 94,-34,-38,-28,-59,-51;
/M: SY='E';  M=-28,-62, 62, 68,-16,-52,-30,-40,-26, 10,-36,  8,-50,-15,-36,-31,-38,-33,-60,-49;
/M: SY='E';  M=-40,  0, 62, 76,-68,-50,-24,-64, -7,-63,-51, -4,-47, 35,-14,-27,-37,-58,-64,-56;
/M: SY='Q';  M= -4,-51,-29,-22,-35,-24, 34,-21,-14, -7,-16, 40,-51, 65,-14, 10,  0,-25,-44, 32;
/M: SY='L';  M=-45,-40,-70,-66, 37,-73,-56, 30,-59, 60, 53,-65,-70,-56,-57,-58,-39, 17,-43,-26;
/M: SY='M';  M=  1,-46,-36, -1, 37,-50,-35,-14,-24, 36, 39, 35,-58, 12,-17, -3,-33,-25,-45,-28;
/M: SY='K';  M=-35,-64,-29, -7,-64,-46, 47,-58, 87,-56,-43,-21,-43, -7, 16,  1,-33,-56,-60,-42;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='R';  M=-45,-68,-37,-25,-59,-53,-26,-58, 46,-32,-41, 12,-53,-11, 90,-34,-38,-55, 30,-47;
/M: SY='R';  M=-47,-70,-42,-27,-64,-58,-25,-65,  8,-53,-43,-26,-56, -9,106,-36,-40,-57,-58,-51;
/M: SY='N';  M=-16,-57,-14,-26,-42,-11,-21,-47,-14, -3,-39, 91, -8,  4, 21,-12,-19,-48,-63,-51;
/M: SY='I';  M=  5,-39,-41,  6, -6,-28,-51, 51,-46, 11, 23,-52,-28, -7,-51,-42,-26, 43,-54,-29;
/M: SY='N';  M=  9,-16, 12, 16,-14, 11,-36,-24,-26,-36,-40, 31, 27,-11,-40, 13, 24,  1,-60,-39;
/M: SY='M';  M=  0,-33, 23,-16, -3, -1,-14,-15,-18, 21, 25, -9,-32, 24,-28,  2, 14,  2,-54,-35;
/M: SY='D';  M= -3,-51, 48, 21,  8,-15,-36,-27,-31,-12, -3,-10, 31, 25,-29,  6, -8,-10,-58,-42;
/M: SY='W';  M= 14,-52, 35, 25,-51, -4, -7,-21,-29,-37,-44, 23, 32,-15, -7,  1,-11,-32, 68,-37;
/M: SY='D';  M=  0,-48, 36, 25,-41,-11,-33, -6,-29,-11,-35, 24,-12, 25,-36, 34, -3,-14,-62,-51;
/M: SY='D';  M= -3, 29, 42, 13,-55, 26,-17,-43,-33, -4,-27,  7, 18, 15,-28,-11, 16,-42,-63,-55;
/M: SY='D';  M= 10,-47, 38, 29,  7,-11,-36, -8,-33,-26, 12,-19,  3, -6,-41, 26,  9,-16,-55,-26;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 53 in 53 different sequences
Number of true positive hits 51 in 51 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 96.23 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] IBB
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
51 sequences

IMA1A_DICDI (Q557F4), IMA1A_ORYSJ (Q71VM4), IMA1B_ORYSJ (Q9SLX0), 
IMA1_CAEEL  (Q22560), IMA1_HUMAN  (P52292), IMA1_MOUSE  (P52293), 
IMA1_SCHPO  (O14063), IMA1_XENLA  (P52171), IMA1_YEAST  (Q02821), 
IMA2_CAEEL  (P91276), IMA2_SCHPO  (O94374), IMA3_CAEEL  (Q19969), 
IMA3_HUMAN  (O00629), IMA3_MOUSE  (O35343), IMA4_HUMAN  (O00505), 
IMA4_MOUSE  (O35344), IMA5_BOVIN  (A2VE08), IMA5_CHICK  (Q5ZML1), 
IMA5_HUMAN  (P52294), IMA5_MOUSE  (Q60960), IMA5_PONAB  (Q5R909), 
IMA5_RAT(P83953), IMA5_XENLA  (P52170), IMA6_DANRE  (Q503E9), 
IMA6_HUMAN  (O15131), IMA6_RAT(Q56R16), IMA7_BOVIN  (Q0V7M0), 
IMA7_HUMAN  (O60684), IMA7_MOUSE  (O35345), IMA7_PONAB  (Q5RBV0), 
IMA8_BOVIN  (C1JZ66), IMA8_HUMAN  (A9QM74), IMA8_MOUSE  (C0LLJ0), 
IMA8_PIG(C6K7I2), IMAB_DICDI  (Q76P29), IMA_DROME   (P52295), 
IMA_SOLLC   (O22478), IMPA1_ARATH (Q96321), IMPA2_ARATH (F4JL11), 
IMPA3_ARATH (O04294), IMPA4_ARATH (O80480), IMPA5_ARATH (Q9FJ09), 
IMPA6_ARATH (Q9FWY7), IMPA7_ARATH (Q9M9X7), KAPA_EMENI  (G5EB89), 
KAPA_PENRW  (B6HJ92), SPN1_BOVIN  (Q2TBK8), SPN1_CHICK  (Q5ZI43), 
SPN1_HUMAN  (O95149), SPN1_MOUSE  (Q80W37), SPN1_RAT(Q68FP5)
» more

UniProtKB/Swiss-Prot
False positive sequences
2 sequences

TMCO6_HUMAN (Q96DC7), TMCO6_MOUSE (Q8BQX5)

		
PDB
[Detailed view]
26 PDB

1IAL; 1QGK; 1QGR; 1WA5; 2P8Q; 2Q5D; 2QNA; 3GB8; 3GJX; 3LWW; 3NBY; 3NBZ; 3NC0; 3TPO; 4B8J; 4TNM; 5DIS; 5HUW; 5HUY; 5T94; 5TBK; 5V5O; 5V5P; 7LF4; 7LFC; 8GCN
» more