PROSITE entry PS51215
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General information about the entry
| Entry name [info] | AWS |
| Accession [info] | PS51215 |
| Entry type [info] | MATRIX |
| Date [info] |
01-JUN-2006 CREATED;
10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51215 |
| Associated ProRule [info] | PRU00562 |
Name and characterization of the entry
| Description [info] | AWS domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=51; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=46; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.2861123; R2=0.0114865; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=3114.6025391; R2=3.0262697; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=454; H_SCORE=4489; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=280; H_SCORE=3962; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-22; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='D'; M=-13, 12,-51, 20, 4,-45,-26,-13,-45, -9,-47,-33, 5,-31, -4,-21, -2,-10,-36,-60,-39, 0; /M: SY='D'; M=-21, 7,-58, 17, 17,-35,-31,-10,-52,-10,-51,-38, -5,-27, -3,-23,-11,-15,-40,-53,-31, 9; /M: M= -9,-27,-35,-30,-24,-16,-34,-26,-15,-23,-18,-12,-22,-36,-22,-26, -2,-10,-10,-46,-22,-24; /M: SY='M'; M=-13,-34,-28,-38,-28,-16,-38,-26,-16,-27,-12, 4,-29,-28,-21,-32,-10,-13,-16,-42,-23,-26; /M: SY='T'; M=-15,-29,-29,-36,-28,-28,-38,-33, -9, -7,-17,-10,-21,-38,-18,-21,-14, 3, -4,-51,-32,-27; /M: SY='C'; M= -8,-55,116,-65,-65,-40,-56,-66,-21,-55,-30,-29,-45,-57,-46,-56,-14,-13,-19,-50,-48,-65; /M: SY='N'; M=-15, 3,-45, -3, 2,-45,-26, -9,-39, -7,-39,-25, 12,-32, -2,-13, 4, -2,-26,-58,-37, -1; /M: SY='C'; M= -6,-57,109,-65,-64,-41,-56,-66,-23,-55,-31,-30,-48,-44,-47,-56,-18,-20,-21,-51,-50,-64; /M: SY='K'; M= -7,-12,-47,-16, 1,-47,-23,-19,-41, 18,-38,-25, -7,-19, 8, -5, -1, 2,-29,-56,-40, 2; /I: I=-7; MD=-15; /M: SY='P'; M=-13,-14,-49,-13, 1,-41,-34,-13,-42, 10,-39,-30,-14, 13, -3, 1, -9,-13,-33,-48,-31, 0; D=-7; /I: I=-7; MI=0; MD=-15; IM=0; DM=-15; /M: M=-10,-15,-22,-15,-15,-18,-21,-16,-11, -9, -6, -6,-11, -7,-11, -7, -9, -5, -8,-27,-19,-13; D=-7; /I: I=-7; DM=-15; /M: SY='D'; M= -6, 0,-22, 5, -6,-20,-12,-14,-18,-10,-16, -9, -3,-17, -6,-14, -1, -1,-15,-29,-21, -6; D=-7; /I: I=-7; DM=-15; /M: SY='S'; M= -3, 4,-23, 5, 2,-26,-15,-10,-21, -6,-24,-16, 4,-16, -2,-12, 6, 3,-12,-34,-23, 0; D=-7; /I: I=-7; DM=-15; /M: SY='S'; M= -5, -2,-28, -4,-10,-27, 0, -8,-28,-10,-29,-18, 2,-17, -9,-15, 3, 3,-22,-35,-22,-11; D=-7; /I: I=-7; DM=-15; /M: SY='A'; M= 3,-13,-36,-14,-12,-39, -1,-25,-35,-13,-36,-23,-12,-10,-15,-20, 3, -5,-25,-48,-38,-13; D=-7; /I: I=-7; DM=-15; /M: SY='C'; M= -4,-28, 18,-34,-30,-32,-38,-33,-13,-25,-24,-17,-23,-35,-23,-31, -2, 4,-10,-46,-32,-31; D=-7; /I: I=-7; DM=-15; /M: SY='G'; M= -2,-19,-28,-29,-29,-50, 15,-33,-44,-10,-47,-33, -7,-40,-23,-25, -6, -7,-32,-57,-47,-29; /M: SY='C'; M= -9,-39, 73,-46,-45,-44,-50,-53,-30,-44,-37,-33,-32,-38,-36,-47, -8,-16,-26,-55,-49,-47; /M: SY='G'; M=-13, 2,-61, 5,-18,-54, 34,-28,-63,-21,-61,-47, 0,-43,-25,-32,-11,-25,-54,-62,-50,-21; /M: SY='S'; M= -6, 5,-44, 6, 6,-43,-27,-10,-45, -4,-44,-30, 3,-27, -1,-13, 15, 5,-33,-56,-32, 2; /M: SY='D'; M=-17, 24,-53, 31, 4,-49,-18,-15,-55, -7,-55,-41, 18,-32, -7,-17, 4, -2,-44,-65,-45, -1; /M: SY='C'; M=-10,-60,130,-70,-70,-40,-60,-70,-20,-60,-30,-30,-50,-60,-50,-60,-20,-20,-20,-50,-50,-70; /M: SY='L'; M=-19,-47,-33,-49,-34,-13,-54,-28, 1,-29, 7, 3,-40,-42,-22,-32,-23,-14, 1,-32,-15,-29; /M: SY='N'; M=-25, 22,-19, -2,-23,-52,-23, -9,-46,-12,-46,-32, 53,-43,-11,-20, 3, 1,-38,-64,-40,-22; /M: SY='R'; M=-21,-20,-55,-27, -7,-48,-32, -7,-45, 18,-39,-29,-13,-30, 4, 59,-14,-17,-32,-52,-41, -1; /M: SY='M'; M= -1,-38,-32,-41,-20,-21,-40,-29, -9,-14, 1, 19,-33,-32, -8,-25,-14,-12, -4,-41,-29,-16; /M: SY='M'; M=-12,-44,-16,-49,-38,-20,-49,-39, 3,-26, 9, 15,-33,-40,-21,-31,-16, -4, 6,-45,-30,-32; /M: M=-21,-28,-25,-38,-32, 0,-42, -5,-26,-23,-20, -7,-16,-43,-16,-24, -8,-15,-25,-32, 0,-28; /M: SY='I'; M=-19,-33,-30,-42,-37,-15,-48,-30, 7,-27, -8, -3,-23,-42,-25,-27,-15, -2, 4,-44,-19,-35; /M: SY='E'; M=-18, 0,-60, 5, 52,-43,-40, -5,-49, 2,-49,-32,-13,-25, 22,-14, -6,-17,-34,-54,-39, 39; /M: SY='C'; M= -4,-58,120,-67,-66,-40,-56,-67,-21,-56,-30,-29,-49,-56,-48,-58,-17,-19,-19,-50,-49,-66; /M: SY='S'; M= -9, 2,-29, -8,-18,-39,-26,-12,-36,-16,-40,-29, 15,-29,-14,-23, 19, 9,-26,-55,-26,-18; /M: SY='P'; M= -1,-12,-46,-11, -6,-46,-31,-13,-43, 3,-42,-31,-10, 8, -5,-13, 6,-10,-32,-60,-38, -6; /M: SY='S'; M=-10, -4,-49, -8, -3,-48,-10,-18,-46, 0,-44,-32, 0,-32, -4, -7, 4, -8,-34,-59,-42, -4; /I: I=-15; MD=-32; /M: SY='T'; M=-13, -7,-30,-12, -5,-21,-27, -4,-20, -6,-23,-16, -2,-25, -5,-10, -3, 1,-14,-31,-10, -6; D=-15; /I: I=-15; MI=-32; IM=-32; DM=-32; /M: SY='C'; M=-10,-60,130,-70,-70,-40,-60,-70,-20,-60,-30,-30,-50,-60,-50,-60,-20,-20,-20,-50,-50,-70; /M: SY='P'; M=-13,-20,-40,-26,-20,-49,-26,-26,-44, -6,-39,-30,-10, 8,-17,-11, -7,-14,-35,-60,-46,-19; /I: I=-10; MD=-21; /M: SY='C'; M= -3,-47, 30,-53,-46,-29,-45,-45,-15,-34,-11,-13,-38,-42,-33,-33,-14,-16,-10,-40,-35,-43; D=-10; /I: I=-10; MD=-21; /M: SY='G'; M= 0,-16,-48,-21,-26,-49, 45,-31,-53,-21,-52,-35,-11,-24,-25,-30, -6,-22,-45,-52,-48,-25; D=-10; /I: I=-10; MI=0; MD=-21; IM=0; DM=-21; /M: SY='E'; M= -4, -3,-49, -2, 18,-49,-30,-15,-45, 11,-45,-33, -6,-13, 4, -7, 9, -6,-31,-61,-42, 12; /M: SY='H'; M=-22,-12,-52,-21,-11,-32,-31, 4,-44, 1,-36,-27, 2,-29, 3, -9,-10,-16,-37,-42,-10, -6; /M: SY='C'; M=-10,-60,130,-70,-70,-40,-60,-70,-20,-60,-30,-30,-50,-60,-50,-60,-20,-20,-20,-50,-50,-70; /M: SY='S'; M= -7, -9,-41,-16, -3,-42,-11,-13,-46, -3,-44,-26, -1,-33, 2,-14, 3, -4,-35,-53,-36, -3; /M: SY='N'; M=-29, 46,-51, 18, -9,-59,-11, 9,-59, 5,-59,-39, 85,-39, 1, -8, 9, -1,-49,-69,-40, -9; /M: SY='R'; M=-24,-17,-55,-23, 6,-48,-40, 1,-45, 28,-38,-20, -7,-30, 40, 47,-16,-15,-37,-47,-36, 18; /M: SY='R'; M=-18,-26,-38,-28,-20,-39,-39,-21,-39, -4,-36,-25,-21, -9,-10, 17,-14,-19,-33,-52,-39,-16; /M: SY='F'; M=-38,-61,-36,-62,-60, 76,-62,-28, 4,-49, 8, 6,-60,-58,-49,-49,-40,-36, -9,-11, 25,-59; /M: SY='Q'; M=-16,-18,-47,-22, 2,-42,-34, -4,-40, 3,-33,-18, -9,-33, 27, 6, -9,-10,-29,-40,-30, 11; /M: SY='K'; M=-17,-10,-56,-18, 4,-48,-34, -7,-47, 44,-38,-23, -2,-26, 19, 36,-10,-12,-38,-55,-39, 9; /M: SY='R'; M=-21,-17,-55,-24, -6,-37,-32, -1,-46, 11,-37,-28, -9,-24, 3, 22,-12,-19,-38,-50,-30, -3; /M: SY='Q'; M=-17,-12,-52,-14, 10,-41,-38, 0,-45, 21,-35,-19, -4,-24, 36, 3,-11,-11,-36,-48,-30, 18; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 38 in 38 different sequences |
| Number of true positive hits | 38 in 38 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | AWS |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
38 sequences
ASH1L_HUMAN (Q9NR48), ASH1L_MOUSE (Q99MY8), ASH1_DROME (Q9VW15), ASHH1_ARATH (Q84WW6), ASHH2_ARATH (Q2LAE1), ASHH3_ARATH (Q945S8), ASHH4_ARATH (Q9M1X9), ASHR3_ARATH (Q949T8), LIN59_CAEEL (O44757), NSD1_HUMAN (Q96L73), NSD1_MOUSE (O88491), NSD2_HUMAN (O96028), NSD2_MOUSE (Q8BVE8), NSD3_HUMAN (Q9BZ95), NSD3_MOUSE (Q6P2L6), NSD_DROME (Q8MT36), SET2_ASPFU (Q4WTT2), SET2_ASPOR (Q2UTN6), SET2_CANAL (Q59XV0), SET2_CANGA (Q6FX50), SET2_CHAGB (Q2H988), SET2_COCIM (Q1DU03), SET2_CRYNB (P0CO29), SET2_CRYNJ (P0CO28), SET2_DEBHA (Q6BM04), SET2_DROME (Q9VYD1), SET2_EMENI (Q5ASA5), SET2_EREGS (Q757Y8), SET2_GIBZE (Q4IB50), SET2_KLULA (Q6CXP5), SET2_NEUCR (Q7RZU4), SET2_SCHPO (O14026), SET2_USTMA (Q4PBL3), SET2_YARLI (Q6C5G5), SET2_YEAST (P46995), SETD2_HUMAN (Q9BYW2), SETD2_MOUSE (E9Q5F9), SETVS_PLAF7 (Q8IE95)» more
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| PDB [Detailed view] |
47 PDB
3OOI; 3OPE; 4FMU; 4H12; 4YNM; 4YNP; 4YPA; 4YPE; 4YPU; 5JJY; 5JLB; 5JLE; 5LSS; 5LSU; 5LSX; 5LSY; 5LSZ; 5LT6; 5LT7; 5LT8; 5UPD; 5V21; 5V22; 6AGO; 6CEN; 6INE; 6J9J; 6KQP; 6KQQ; 6VDB; 6WZW; 6X0P; 7CRO; 7CRP; 7CRQ; 7CRR; 7E8D; 7EA5; 7EA8; 7LZB; 7LZD; 7LZF; 7TY2; 7TY3; 8FBG; 8FBH; 8Q5P » more |