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Entry: PS51224

General information about the entry

Entry name [info] MVP
Accession [info] PS51224
Entry type [info] MATRIX
Date [info] 01-JUL-2006 CREATED;
01-OCT-2013 DATA UPDATE;
13-NOV-2019 INFO UPDATE.
PROSITE Doc. [info] PDOC51224
Associated ProRule [info] PRU00571

Name and characterization of the entry

Description [info] MVP (vault) repeat profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=55;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=55;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.6992440; R2=0.0082208; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=889; N_SCORE=9.0; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=353; N_SCORE=4.6; MODE=1; TEXT='R?';
/DEFAULT: M0=-17; D=-80; I=-80; B1=-200; E1=-200; MI=-210; MD=-210; IM=-210; DM=-210;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-210; BD=-210;
/M: SY='P';  M= 13,-57,  6, 34,-59, -7, 10,-56, 10,-41,-47, 21, 55,  6, 12, -7, -7,-52,-61,-50;
/M: SY='N';  M=-28,-55, 19, 28,-23, 22, 42,-57,-15,-38,-46, 58,-23, 34,-21, -1,-15,-56,-61,-14;
/M: SY='Y';  M=-42,-59,  0, 53,-31,-51, -7,-32, -7,-34,-40, -6,-48, 43,-34,  4,  2,-48,-37, 76;
/M: SY='C';  M= 51, 84,-51,-50,-21, 39,-51,-15,-49,-47,-43,-22,-54,-48,-54,-12,-38, -9,-57, -3;
/M: SY='I';  M=-43, 14,-60,-21,-28,-66,-54, 57,-53, 46,-17,-56,-58,-51,-31,-51,-10, 32,-54, -1;
/M: SY='H';  M=-34,-56,-51,-47,-29,-37, 67, 33,-27, 11,-26,-45,-27, -5,  5,-25,-22, 28, 16, 49;
/M: SY='V';  M=-10, -4,-55, -8,-32,-59, -3, 19,-49, 43,-21,-53,-57, -1,-27,-15,-37, 50,-57,-11;
/M: SY='R';  M=-20,  7, -7, 12,-54,-46,  6,-51, 12,-27, 21, 46,-20, 21, 54,  6,-10,-39,-62,-45;
/M: SY='P';  M= 59,-12, 10,-37,-58,-38,-48,-45,-42,-52,-45,  8, 71,-42,-50,-19, -9, -4,-61,-54;
/M: SY='V';  M=-29, -1,-51,-49,-13,-57, 32,  3,-13, 33, -5,  2,-56,-44, -7,-12, 14, 43,-57,  4;
/M: SY='R';  M= -8,  8, -1, 22,-50, 12, 11,-29, 23,-39,-20, -3,-22, 12, 24,  5,-21,  9,-57, -1;
/I:         I=-10; MD=-26;
/M: SY='D';  M=-27,-59, 51, 14,-63,-51,-43,-58,-16,-60,-54, 19,  0,-19, 25, -1, 40,-35,-73,-54; D=-10;
/I:         I=-10; MI=0; MD=-26; IM=0; DM=-26;
/M: SY='F';  M=-66,  4,-75,-37, 64,-49,-10,-27,-49,-15,-49,-70, -8,-70,-24,-67,-62, -8,-53,  8; D=-10;
/I:         I=-10; DM=-26;
/M: SY='T';  M=-42, -9,-34,-16,  4,-30,-62,-34,-15,-12,-51,-27,-36, -9,-11,-24, 28,  2,-14,-54; D=-10;
/I:         I=-10; DM=-26;
/M: SY='D';  M=-57,-71, 71, 22,-67,-61,-11,-70,-28,-45,-25,-21,-59,-44,-25,-18, -2,-67,-79, -2; D=-10;
/I:         I=-10; DM=-26;
/M: SY='R';  M= -3,-65, -8,  7,-40,  5,-54,-24,  4,-31,-54,-19,  2,-44, 15,  9,-13,-31,-70,-58; D=-10;
/I:         I=-10; DM=-26;
/M: SY='D';  M=-13,-61, 47,  2, -4,-52, 14,-55, -3,-39,-52, 18,-56,-14,-30, 11,  5,-24,-63, 15; D=-10;
/I:         I=-10; DM=-26;
/M: SY='G';  M=-32,-17,-18,-50,-58, 79,-49,-57,-46,-59,-51, -4,-25,-16,-33,  3, 14,-14,-58,-25; D=-10;
/I:         I=-10; DM=-26;
/M: SY='V';  M=-38,-53,-17,-14,-46,  2,-16,  4, 23,-10, -4,-12,-51, 30, -4,-27, 19, 44,-62,-44; D=-10;
/I:         I=-10; DM=-26;
/M: SY='V';  M= 14,-53, -6, 10,-47,-51, -9, -8,  8,-21, -4, -1,  5,  4, -4,-17,  0, 40, 27,-44; D=-10;
/I:         I=-10; DM=-26;
/M: SY='R';  M=-33,-19,-44,-19,-55,-56,  2,-52, 22,-28,-42,-38, 12, 26, 85,-28,-30,-13,-58,-44; D=-10;
/I:         I=-10; DM=-26;
/M: SY='V';  M= -9, 24,-18,  3,-10,-56, 18, 12,  9,  3, -7, -3,-54,-39, 23,-18,-21, 37,-61,-41; D=-10;
/I:         I=-10; DM=-26;
/M: SY='A';  M= 30,-20,-32,-44,-48,-38, -9,-26,  4,-16, -5,-44, 12,-22, 18,  7,  4, 12,-58, 10; D=-10;
/I:         I=-10; MI=0; MD=-26; IM=0; DM=-26;
/M: SY='G';  M=-12,-57,-41,-50,-63, 86,-47,-67,-45,-65,-54, 26, 13,  0,-53,-21,-44,-62,-56,-57;
/M: SY='E';  M=-30, -6, 53, 68,-60,-50, 16,-33,  8,-53,-49,-30,-43, 13,-18,  5,-21,-13,-66,-48;
/M: SY='R';  M=-15,  9,-36, 31,-54,-51, 10,-47, 29,-25,-42,-36, 12, 20, 49,  5,  7, -3,-60,-46;
/M: SY='W';  M=-50,-67,-48, 31, 14,-57,-42,-29,  4,-35,-43,-53,-54,-36, 14,-50,-51,-52,130, 67;
/M: SY='M';  M=-32,-51,-63,-57,-26,-63,-49, 35,-55, 54, 63,-32,-59,-50,-54,-52,-29, 32,-53,  0;
/M: SY='V';  M=-42, -2,-57,-29, 24,-39, -5, 18,-41, 25,  8,-52,-59,-46, 37,-48,-40, 51,-53, -9;
/M: SY='T';  M=-15,-12,-42, -8, 12,-52, 11,-37, 31,-10,-37,-17,-49,  4,  7,-11, 52,  9, 11,  7;
/M: SY='G';  M= 19, -9,-25,  3,-53, 65, 20,-55,-13,-36,-46,-34,-48,  9,-22,-18, -3,-26,-54,  0;
/I:         I=-22; MD=-58;
/M: SY='Q';  M=-42,-84, 24, 14,-87,-72,-21,-77,-38,-80,-74,-13, -4, 27,-62,-15,-41,-31,-91,-74; D=-22;
/I:         I=-22; MD=-58;
/M: SY='E';  M=-72, 26, 25, 30,-89,-36,-69,-88,-27,-54,-79,-62,  0,-21,-68,-67,-47,-84,-95,-82; D=-22;
/I:         I=-22; MI=-58; IM=-58; DM=-58;
/M: SY='P';  M=-13, 25,-21, -2,-56,-28,-49,-33,-41,-39,-47,-22, 93,-21,-29,  9, -6,-21, 50,-52;
/M: SY='F';  M= -7, 35,-28,  1, 60, 35,-48,-30, -5,  0,-38,-44,  6,-23,-21,-33,-28,-32, 16,-29;
/M: SY='P';  M= -5, -1,-27, 24, 28,-49,-44,-32, -3,-15, 28,-40, 44,-23,-43, 17, 40,-20,-54,-39;
/M: SY='Y';  M=-23,-56,-53,-31, 43,-59, 38,-29,-28, 35,-24,-51,-61,-19,-45,-48,-44,-13,-27, 86;
/M: SY='I';  M=-44,-12,-54,-45,  6,-60,  6, 48,  1, 16, -8,-48,  7, 36,-44,-46,-22, 18,-46, 38;
/M: SY='P';  M=-45,-22,-49,-39,-56,-31,-49,-27,-40, -4,-42,-52,108,-45, 10,-28,-40,-24,-59,-56;
/M: SY='G';  M=-17,-59, 15,  0,-59, 42, 25,-61,-16,-58,-48,-18, 34, 36, 36,  8,-24,-57,-58,-17;
/M: SY='E';  M=-10,-57, 28, 51,-51,-54,-45,-24, -7,-16, -7,-42, 51,-34,-21,-40,-23, 36,-63,-49;
/M: SY='H';  M=-27,-54,  7, 34, -9,-50, 47,-39,-17,-10,-38, 21,-49,  3,-19,  4, 21,  9,-52, 38;
/M: SY='E';  M=-13, -6,-11, 69,-44,-58,-43,-29,-35, 21, 16,-45,-47,-30,-21,-41,-14, 32,-61,-46;
/M: SY='E';  M=-26,-19, 12, 39,-54,-50, 21,-32, 36,-28,-43,-33,-25, 17, 32, 11,  6,-10, 13,-44;
/M: SY='V';  M=-28, 10,-16,-17, -6, -9,-52, 28,  1, 13, -6,-48,-27,  5,  0,-45,-38, 51,-58,-40;
/I:         I=-22; MD=-58;
/M: SY='L';  M=-50,-19,-35, 10,-43,-48,-56,  3,-37, 39,-31,-18,-64,-20, -5,-44,-25, 28,-67,-49; D=-22;
/I:         I=-22; MI=-58; MD=-58; IM=-58; DM=-58;
/M: SY='E';  M=  2, -8, -2, 48,-29, 23,-16,-63, 16,-42,-54,-40,-26,-34,  1,  0,-16,-57,-64,-54; D=-22;
/I:         I=-22; DM=-58;
/M: SY='V';  M=-29,-55,-11, -8, -6,-21,-17, 21,  0,-20, -7,-15, 32, 25,  6,-40,  9, 37,-57,-22;
/M: SY='V';  M=-15,-10,-20, 13,-31,-54,-13,-11, -3,-18, -5,-41,-52, 26, 41,  1, -1, 43,-58, -7;
/M: SY='P';  M=-42, -6, 13, 14,-57,-48, 27,-54, 34,-55,-17, 12, 54, 10, 25,  4, -2,-30, 15,-46;
/M: SY='M';  M= 39,-51,-52,-45,-42,  8,-46, -6,-17, 18, 47,-46, 20,-14,  2,-36, -8,  3,-54,-14;
/M: SY='Y';  M=-19, -8,-52,-35, 17,-58,-15, 38,-10, 17, 26,-10,-25,-21,-25,-42, 22, 15,-46, 39;
/M: SY='M';  M=-20,-51,-51,-48,-12,-54, 27, 32,-18,  5, 33,-28, 13,-44,-30, 11, 26, 32,-56,  4;
/M: SY='L';  M=-28,-50,-35,-35,-14,-63,-53, 25,-55, 58, 21,-57,-60,-51,-55,-19,-38, 44,-56,-36;
/M: SY='S';  M=-36,-15, 29, 23,-29, -7,-14,-29,-11,-22,-14,-13, 19,-33,  3, 43, 32,-45,-60,-15;
/I:         E1=0; IE=-210; DE=-210;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2019_10 which contains 561'356 sequence entries.


Total number of hits 140 in 18 different sequences
Number of true positive hits 140 in 18 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] PS_Langendijk_Genevaux
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 8
Feature key [info] REPEAT
Feature description [info] MVP
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
18 sequences

MVPA_DICDI  (P34118    ), MVPB_DICDI  (P54659    ), MVP_BOVIN   (Q3SYU9    ), 
MVP_CHICK   (Q5ZMI4    ), MVP_DANRE   (Q6P3L0    ), MVP_DIPOM   (Q90405    ), 
MVP_HUMAN   (Q14764    ), MVP_ICTPU   (Q9DGM7    ), MVP_LEIBR   (A4H452    ), 
MVP_LEIIN   (A4HSC9    ), MVP_LEIMA   (Q4QJJ7    ), MVP_MOUSE   (Q9EQK5    ), 
MVP_PONAB   (Q5R9N2    ), MVP_RAT     (Q62667    ), MVP_STRPU   (Q5EAJ7    ), 
MVP_TRYB2   (Q57Z03    ), MVP_TRYCC   (Q4CUM2    ), MVP_XENLA   (Q6PF69    )
» more

PDB
[Detailed view]
8 PDB

1Y7X; 2QZV; 3GF5; 3GNF; 3GNG; 4HL8; 6BP7; 6BP8

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