PROSITE entry PS51247

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PURL: https://purl.expasy.org/prosite/signature/PS51247

Direct ScanProsite submission

General information about the entry

Entry name [info]	NIKD
Accession [info]	PS51247
Entry type [info]	MATRIX
Date [info]	01-AUG-2006 CREATED; 01-OCT-2013 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51237

Name and characterization of the entry

Description [info]

Nickel import ATP-binding protein nikD.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=52;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=47;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.6773194; R2=0.0113544; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=880481; N_SCORE=9999.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=1614; N_SCORE=20.0; MODE=1; TEXT='?';
/CUT_OFF: LEVEL=-2; SCORE=425; N_SCORE=6.5; MODE=1; TEXT='??';
/DEFAULT: M0=-8; D=-50; I=-50; B1=-1000; E1=-1000; MI=-105; MD=-105; IM=-105; DM=-105;

...

                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='M';  M=-10,-20,-20,-30,-20,  0,-20,  0, 20,-10, 20, 60,-20,-20,  0,-10,-20,-10, 10,-20,  0,-10;
/M: SY='G';  M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='V';  M=  0,-30,-10,-30,-30,  0,-30,-30, 30,-20, 10, 10,-30,-30,-30,-20,-10,  0, 50,-30,-10,-30;
/M: SY='V';  M=  0,-30,-10,-30,-30,  0,-30,-30, 30,-20, 10, 10,-30,-30,-30,-20,-10,  0, 50,-30,-10,-30;
/M: SY='A';  M= 50,-10,-10,-20,-10,-20,  0,-20,-10,-10,-10,-10,-10,-10,-10,-20, 10,  0,  0,-20,-20,-10;
/M: SY='R';  M=-20,-10,-30,-10,  0,-20,-20,  0,-30, 30,-20,-10,  0,-20, 10, 70,-10,-10,-20,-20,-10,  0;
/M: SY='C';  M=-10,-25, 47,-30,-25, -4,-30,-25, -4,-30, 17,  1,-25,-35,-25,-25,-20,-10,  0,-34,-14,-25;
/M: SY='A';  M= 50,-10,-10,-20,-10,-20,  0,-20,-10,-10,-10,-10,-10,-10,-10,-20, 10,  0,  0,-20,-20,-10;
/M: SY='D';  M=-20, 50,-30, 70, 20,-40,-10,  0,-40,  0,-30,-30, 20,-10,  0,-10,  0,-10,-30,-40,-20, 10;
/M: SY='D';  M=-15, 26,-30, 37, 20,-40,-15,  5,-31,  5,-25,-16, 10,-10, 28,  0,  0,-10,-30,-31,-15, 24;
/M: SY='V';  M=  0,-30,-10,-30,-30,  0,-30,-30, 30,-20, 10, 10,-30,-30,-30,-20,-10,  0, 50,-30,-10,-30;
/M: SY='A';  M= 50,-10,-10,-20,-10,-20,  0,-20,-10,-10,-10,-10,-10,-10,-10,-20, 10,  0,  0,-20,-20,-10;
/M: SY='V';  M=  0,-30,-10,-30,-30,  0,-30,-30, 30,-20, 10, 10,-30,-30,-30,-20,-10,  0, 50,-30,-10,-30;
/M: SY='M';  M=-10,-20,-20,-30,-20,  0,-20,  0, 20,-10, 20, 60,-20,-20,  0,-10,-20,-10, 10,-20,  0,-10;
/M: SY='E';  M=  0,  5,-19,  9, 28,-25, -9, -5,-25,  0,-25,-20,  5, -5,  9, -5, 21,  6,-19,-35,-20, 19;
/M: SY='D';  M= 13, 21,-20, 27,  6,-31, -5, -9,-26, -5,-20,-20,  6,-10, -5,-15,  5, -5,-16,-31,-20,  0;
/M: SY='G';  M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='R';  M=-15, -5,-30, -5,  5,-25,-20, -5,-30, 40,-25,-10,  0,-15, 10, 49,-10,-10,-20,-20,-10,  5;
/M: SY='I';  M=-10,-30,-30,-40,-30,  0,-40,-30, 50,-30, 20, 20,-20,-20,-20,-30,-20,-10, 30,-20,  0,-30;
/M: SY='V';  M=  0,-30,-10,-30,-30,  0,-30,-30, 30,-20, 10, 10,-30,-30,-30,-20,-10,  0, 50,-30,-10,-30;
/M: SY='E';  M=-10, 10,-30, 20, 60,-30,-20,  0,-30, 10,-20,-20,  0,  0, 20,  0,  0,-10,-30,-30,-20, 40;
/M: SY='C';  M=-10, -9, 41,-14, -4,-31,-25, -9,-25, -9,-20, -9, -9,-24, 17, -9, -5,-10,-20,-34,-19,  7;
/M: SY='G';  M= -5, -5,-30, -5, -1,-35, 27, -6,-31, -6,-25,-10,  0,-15, 18, -6,  0,-15,-30,-20,-20,  9;
/M: SY='P';  M=-15, 17,-35, 32, 10,-35,-15, -9,-31, -5,-30,-25,  1, 38, -5,-15, -5,-10,-30,-35,-25,  0;
/M: SY='V';  M= 24,-20,-10,-25,-20, -9,-16,-25, 11,-15,  0,  0,-20,-20,-20,-20,  0,  0, 26,-25,-15,-20;
/M: SY='H';  M=-15,  5,-30, 10, 31,-25,-20, 47,-30,  0,-20,-10,  5, -9, 15,  0, -5,-15,-30,-30, -1, 21;
/M: SY='E';  M= -5,  5,-19,  4, 23,-19,-20,-10,-19,  0,-15,-15,  0, -5,  4, -5, 10, 21,-14,-30,-15, 14;
/M: SY='L';  M=-10,-30,-20,-30,-20, 10,-30,-20, 20,-30, 50, 20,-30,-30,-20,-20,-30,-10, 10,-20,  0,-20;
/M: SY='F';  M=-20,-30,-20,-40,-30, 80,-30,-20,  0,-30, 10,  0,-20,-30,-40,-20,-20,-10,  0, 10, 30,-30;
/M: SY='N';  M=-10, 21,-25, 10,  9,-29, -9, 10,-20,  5,-25,-10, 31,-15, 28,  5,  5, -5,-30,-31,-15, 19;
/M: SY='R';  M= 17,-10,-19,-15, -5,-20, -9,-10,-19,  9,-15,-10, -5,-15,  0, 23,  0, -5, -9,-20,-15, -5;
/M: SY='P';  M=-10,-20,-40,-10,  0,-30,-20,-20,-20,-10,-30,-20,-20, 90,-10,-20,-10,-10,-30,-30,-30,-10;
/M: SY='K';  M= 19, -5,-20, -9,  0,-25,-10,-15,-20, 21,-20,-10, -5,-10,  0,  6,  0, -5,-10,-20,-15,  0;
/M: SY='H';  M= -6,  0,-20,  0,  0,-20,-10, 48,-25,-10,-25, -9, 10,-15,  5, -5, 14, -1,-20,-35,  1,  0;
/M: SY='A';  M= 50,-10,-10,-20,-10,-20,  0,-20,-10,-10,-10,-10,-10,-10,-10,-20, 10,  0,  0,-20,-20,-10;
/M: SY='V';  M=  0,-16,-10,-20,-20, -5,-25,-25, 11,-15,  0,  0,-16,-20,-20,-15,  4, 24, 26,-30,-10,-20;
/M: SY='T';  M= 24, -5,-10,-15,-10,-15,-10,-20,-10,-10,-10,-10, -5,-10,-10,-15, 15, 26,  0,-25,-15,-10;
/M: SY='R';  M=-20,-10,-30,-10,  0,-20,-20,  0,-30, 30,-20,-10,  0,-20, 10, 70,-10,-10,-20,-20,-10,  0;
/M: SY='T';  M=  5,  0,-10, -5, -5,-15, -9,-15,-15,-10,-20,-15,  5,-10, -5,-10, 31, 34, -5,-35,-15, -5;
/M: SY='L';  M=-10,-30,-20,-30,-20, 10,-30,-20, 20,-30, 50, 20,-30,-30,-20,-20,-30,-10, 10,-20,  0,-20;
/M: SY='V';  M= -5,-30,-15,-30,-25,  5,-30,-25, 25,-25, 29, 15,-30,-30,-25,-20,-19, -5, 31,-25, -5,-25;
/M: SY='H';  M= -4,  0,-19,  0,  0,-20, -9, 42,-25,-10,-25,-10, 10,-15,  5, -5, 16,  1,-19,-35, -1,  0;
/M: SY='A';  M= 50,-10,-10,-20,-10,-20,  0,-20,-10,-10,-10,-10,-10,-10,-10,-20, 10,  0,  0,-20,-20,-10;
/M: SY='H';  M=-20,  0,-30,  0,  0,-20,-20,100,-30,-10,-20,  0, 10,-20, 10,  0,-10,-20,-30,-30, 20,  0;
/M: SY='Q';  M=-10,-16,-25,-16, -1,-14,-25, -6,  1,-11, 17, 10,-16,-20, 18, -6,-16,-10, -9,-20, -5,  9;
/M: SY='A';  M= 26,-19,-10,-25,-19,-10,-14,-25,  9,-15,  0,  0,-19,-19,-19,-20,  0,  0, 24,-25,-15,-19;
/M: SY='L';  M=-10,-30,-20,-30,-20, 10,-30,-20, 20,-30, 50, 20,-30,-30,-20,-20,-30,-10, 10,-20,  0,-20;
/M: SY='C';  M=-15,-20, 41,-25,-25,  6,-30, -4,-14,-19, -9, -9,-20,-35,-19,-19,-15,-10,-10, -8, 28,-25;
/M: SY='G';  M= -9,-10,-30,-10,-10,-25, 27,-10,-35,  4,-25,-15,  0,-20, -6, 23, -5,-15,-25,-20,-20,-10;
/M: SY='M';  M=  0,-10,-15,-16,-10, -9,-10, -5,  1,-10, -4, 22, -6,-15,  0,-10,  9,  4,  0,-29, -9, -5;
/M: SY='E';  M=-10,  5,-30, 10, 41,-35,-20,  5,-25, 10,-20,-10,  0, -5, 39,  5,  0,-10,-30,-25,-15, 40;
/M: SY='P';  M=-10,-25,-29,-20,-10, -9,-25,-20,  1,-20, 12,  1,-25, 27,-15,-20,-20,-10, -9,-25,-14,-15;
/I:         E1=0; IE=-105; DE=-105;

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Post-processing [info]

PROMOTED_BY

PS50893

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	16 in 16 different sequences
Number of true positive hits	16 in 16 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Taxonomic range [info]	Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	V_Lesaux
Version [info]	3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

16 sequences

NIKD_BRUA2  (Q2YL70), NIKD_BRUAB  (Q578S8), NIKD_BRUME  (Q8YCN8),

NIKD_BRUSU  (Q8FVM9), NIKD_ECO57  (Q8X5U1), NIKD_ECOL5  (Q0TBX9), 
NIKD_ECOL6  (Q8FCN0), NIKD_ECOLI  (P33593), NIKD_ECOUT  (Q1R5D9), 
NIKD_PSEPK  (Q88HL1), NIKD_RHORT  (Q2RS21), NIKD_SHIBS  (Q31VE7), 
NIKD_SHIDS  (Q32AQ2), NIKD_SHIF8  (Q0SZJ4), NIKD_SHIFL  (Q83J78), 
NIKD_SHISS  (Q3YW49)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment