PROSITE logo

PROSITE entry PS51256


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] GS
Accession [info] PS51256
Entry type [info] MATRIX
Date [info] 01-OCT-2006 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51256
Associated ProRule [info] PRU00585

Name and characterization of the entry

Description [info] GS domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=30;
/DISJOINT: DEFINITION=PROTECT; N1=4; N2=27;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.6356133; R2=0.0071500; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2852.9260254; R2=0.4629630; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=961; H_SCORE=3298; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=681; H_SCORE=3168; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-36; D=-20; I=-20; B1=-200; E1=-200; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-105; BD=-105;
/M: SY='P';  M=-54,-72,-53, -3,-75, 13,-59,-73, 30,-77,-68, 41, 51,-30,-40, 45, 42,-69,-79,-21;
/M: SY='T';  M=-34,-46,-53, 27,-13, -7, 23,-24,-23,-47,  1, 29,-41,-24,-29,  7, 74,-59,-78,  5;
/M: SY='M';  M=-61,-72,-80,-75,-46,-35,-26, 43,-73, 47, 68,-73,-77,-67,-72, -4,-40, 23, 42, 19;
/M: SY='Q';  M=-31,-76, 31, 33,-40,  0, 31,-70, 31,-68, 42,-20,-15, 50, -5, 16,-57,-31,-79,-63;
/M: SY='D';  M=-33,-80, 87, 49,-85,-22,-56,-81,-11,-80,-75,-38, 35, 11,-58, -8,-19,-78,-88,-71;
/M: SY='M';  M=-21,-71,-37,-69,  1,-73,-61, 33,-16, 44, 68, -5,-75,-62,-66, 25,-56,-43,-66, 33;
/M: SY='I';  M= -1,-73,-75,-69, 15,-75,-69, 50, -5, 26, 25,-68, 10,-64,  1, -2, -2, -6, 41,-14;
/M: SY='D';  M= -7,-76, 66, 42,-37,-59,-44,-65,-18,-44, 25,-31,  3, 13,-59,  6,-56, -6,-73, 42;
/M: SY='M';  M=-38,-74, 55, 27,-64,-14, 39,-41,-59, 16, 78,-55,-69,  2,-63,  1,-58,  1,-82,-59;
/M: SY='M';  M= -9,-69, 20,-63, 21,-69,-14,-12,-41, 30, 45,-59,-71,-61,-67, 35, 34,-15,-70, 23;
/I:         I=-5; MI=0; MD=-25; IM=0; DM=-25;
/M: SY='C';  M= -9, 64,  0, 36,-72,-68,-64, 14,-56,-63,-60,-54,-16, 43,-62, 26, 51,-11,-83,-68;
/M: SY='T';  M=-33,-12, 33,-56,-72, 16,-63,-69,-58,-72,-67,-45,-63,-57,-65, 61, 78,-62,-85,-37;
/M: SY='S';  M=-44,  3,-58,-60,-75, 30,-62,-74,-59,-77,-70,-46,-64,-53,-64, 95, 24,-67,-82,-68;
/M: SY='G';  M=-47,-74,-63,-72,-81, 95,-69,-87,-67,-84,-74,-49,-67,-63,-74, 39,-60,-80,-75,-75;
/M: SY='S';  M=-42, 10,-57,-59,-75, 17,-60,-75,-59,-78,-71,-45,-65,-51,-63,102,-39,-68,-82,-68;
/M: SY='G';  M=-48,-74,-63,-73,-81, 96,-69,-86,-67,-84,-74,-49,-67,-64,-74, 21, -5,-80,-75,-76;
/M: SY='S';  M= 17,-64,-58,-58,-72,-52,-60,-68,-58,-69, 32,-47,-64,-51,-62, 96, 21,-61,-81,-65;
/M: SY='G';  M=-49,-77,-64,-76,-83,103,-71,-91,-70,-86,-75,-50,-68,-67,-77,-49,-68,-84,-74,-78;
/M: SY='L';  M=-66,-73,-73,-64, -5,-78,-63,-43, 19, 69, 31, -4, 34, 21,-61,-68,-61,-49,-71,-56;
/M: SY='P';  M= 20,-83,-66,-56,-83,-65,-70,-71,-62,-80,-68,-69,118,-65,-73,-57,  7,-72,-79,-80;
/M: SY='L';  M= -6,-68,-76,-72, 41,-77,-64,-41,-72, 67,-39,-71,-78,-69,-71,-19, 33,-46,-62, 34;
/M: SY='L';  M=-67,-69,-85,-77,  2,-86,-68,-33,-78, 88, 23,-83,-84,-71,-74,-77,-63,-40,-69,-51;
/M: SY='V';  M=-54,-68,-75,-73,-56,-79, 33, 23,-71,-19,-44, -9,-76,-71,-73,-13,  1, 87,-87,-59;
/M: SY='Q';  M=-59,-83,-54,-35,-87,-67,-16,-76, 26,-72,-59,-49,-66,123,-38, -9,-60,-77,-73,-61;
/M: SY='R';  M=-46,-82,-64,-51,-73,-76,-53,-76,-27,-15,-60,-57,-75, 25,110,-61,-65,-72,-75,-62;
/M: SY='T';  M=-50,-62,-57,-60,-69,-64,-66,-61,-57,-66,-62,-46,-60,-59,-65, 43,106,-53,-87,-66;
/M: SY='I';  M=-61,-73,-85,-81,  7,-87,-82, 87,-77,-14, 26,-77,-76,-75,-79,-71,-57, 53,-74,-54;
/M: SY='A';  M= 88,-64,-66,-60,-76,  0,-67,-68,-58,-69,-63,-59,-67,-57, 11, 14,-52,-56,-76,-71;
/M: SY='R';  M=-20,-80,-60,-49,-78, -5,-53,-81, 30,-75,-64,  3,-72, 39, 97,-56,-63,-75,-75,-64;
/M: SY='Q';  M=-60,-79, 40,-38,-84,-66, -8,-75,-43,-72,-62,  5,-66,110,  4,-31, 31,-74,-79,-63;
/I:         E1=0; IE=-105; DE=-105;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.


Total number of hits 28 in 28 different sequences
Number of true positive hits 28 in 28 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] GS
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
28 sequences

ACV1B_HUMAN (P36896), ACV1B_MOUSE (Q61271), ACV1B_RAT   (P80202), 
ACV1C_HUMAN (Q8NER5), ACV1C_MOUSE (Q8K348), ACV1C_RAT   (P70539), 
ACVL1_HUMAN (P37023), ACVL1_MOUSE (Q61288), ACVL1_PONAB (Q5RAN0), 
ACVL1_RAT   (P80203), ACVR1_BOVIN (Q28041), ACVR1_CHICK (Q90ZK6), 
ACVR1_HUMAN (Q04771), ACVR1_MOUSE (P37172), ACVR1_RAT   (P80201), 
BMR1A_HUMAN (P36894), BMR1A_MOUSE (P36895), BMR1A_RAT   (Q78EA7), 
BMR1B_CHICK (Q05438), BMR1B_HUMAN (O00238), BMR1B_MOUSE (P36898), 
DAF1_CAEEL  (P20792), SMA6_CAEEL  (Q09488), TGFR1_BOVIN (O46680), 
TGFR1_HUMAN (P36897), TGFR1_MOUSE (Q64729), TGFR1_PIG   (Q5CD18), 
TGFR1_RAT   (P80204)
» more

PDB
[Detailed view]
12 PDB

1B6C; 1IAS; 1PY5; 2X7O; 3FAA; 3H9R; 3KCF; 3MDY; 4C02; 6EIX; 6I1S; 8YHF