PROSITE entry PS51265
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS51265 |
| Entry name [info] | ZF_DBF4 |
| Accession [info] | PS51265 |
| Entry type [info] | MATRIX |
| Date [info] |
01-NOV-2006 CREATED;
10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51265 |
| Associated ProRule [info] | PRU00600 |
Name and characterization of the entry
| Description [info] | Zinc finger DBF4-type profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=50; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=45; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.8617007; R2=0.0085572; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=6242.0429688; R2=2.0071943; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=987; H_SCORE=8223; N_SCORE=10.3; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=543; H_SCORE=7332; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-16; D=-50; I=-50; B1=-200; E1=-200; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='Q'; M= -9,-45,-27, 9,-43, -1,-26,-17, 27,-23, 23,-23, 0, 50, 35, 11,-16,-22,-44,-33; /M: SY='Q'; M=-17,-47, 43, 31,-46,-39, 23,-36, 20,-37, -4,-19,-35, 50, 28,-25,-28, 2,-50,-32; /M: SY='K'; M=-20,-46,-28, 5,-40,-40, 5,-36, 45, 2,-27,-25, 45, 23, 27,-25, 15,-35,-45,-33; /M: SY='K'; M=-10,-45,-25,-15,-46,-19,-25,-46, 64,-44,-33, 5,-35, 21, 53, -4, -4,-41,-44,-34; /M: SY='P'; M= 1, 15,-26, 3,-49, 8, 5,-45, 29,-46,-36,-22, 52, 31,-21, 32,-22,-41,-47,-38; /M: SY='G'; M= 0,-45,-32,-38,-52, 85,-37,-56,-34,-52,-41,-19,-37, 18,-41,-17,-35,-50,-42,-44; /M: SY='Y'; M=-39,-50,-42,-43, 26,-47,-11,-22,-36,-21,-19,-42,-52,-32,-33,-36,-34, -3, 57,109; /M: SY='C'; M=-30,142,-50,-50,-40,-45,-50,-47,-46,-38,-38,-36,-61,-53,-52,-32,-30,-35,-70,-51; /M: SY='E'; M=-27, 40, -3, 88,-50,-42,-24,-52,-13,-45,-41,-25,-27, -6,-23, 3,-27,-44,-50,-42; /M: SY='N'; M=-31, 75,-21,-36,-30,-32,-24, 28,-29,-30,-26, 77,-46,-30,-35,-23,-21, -3,-50, 15; /M: SY='C'; M=-30,142,-50,-50,-40,-45,-50,-47,-46,-38,-38,-36,-61,-53,-52,-32,-30,-35,-70,-51; /M: SY='R'; M=-33, 7,-27, 2,-37,-42,-22,-42, 44,-12,-28, 3,-40, 33, 65,-27,-30,-40,-40, 10; /M: SY='V'; M=-27,-42, 23, 33,-32,-46,-35, 28,-12, -4,-19,-30,-38, 24,-31,-29, -2, 43,-51,-32; /M: SY='K'; M=-13,-46,-18, 39,-48,-39,-25,-47, 70,-44,-35,-19,-31, 23, 25,-23, -3,-41,-43,-35; /M: SY='Y'; M=-42,-45,-47,-47, 82,-49,-18,-21,-40,-15,-19,-43,-53,-42,-37,-39,-35,-26, -2, 90; /M: SY='D'; M=-18,-44, 66, 48,-50,-33,-22,-48, -4,-47,-42, 31,-32,-15,-11, 6, 13,-43,-58,-39; /M: SY='D'; M=-29,-42, 67, 1,-38,-32, 5, -2,-25,-37,-35, 42,-37,-23,-32, 16, 0, 0,-55, 5; /M: SY='F'; M=-39,-40,-52,-47, 65,-53,-31, -8,-45, 55, -6,-48,-53,-43,-42,-43,-33,-15,-20, 44; /M: SY='E'; M= -2,-45, 37, 62,-39,-36, 16,-46, 16,-43,-37, 1,-31,-12,-20, 2, -9,-41,-44, 21; /M: SY='Q'; M= -3,-44, 24, 47,-43,-38,-26, -1,-18,-22,-28, 2,-34, 50, -6, -1, -5, 6,-49,-35; /M: SY='H'; M=-38,-50,-22,-22,-36,-40,132,-55,-27,-37,-22,-11,-39,-16,-21,-27,-37,-54,-72, -5; /M: SY='I'; M=-32,-41,-54,-49,-15,-56,-47, 63,-47, 45, -2,-48,-47,-43,-47,-42,-27, 34,-43,-25; /M: SY='M'; M= -5,-41,-29, 20, 11,-18,-29,-19, 9, 7, 25, 5,-39, 19, 1, 0,-25, 20,-40, -1; /M: SY='S'; M= -2,-35, -3, 23,-44, 7,-29,-42,-24,-44,-38,-15,-31,-18,-30, 69, 29,-34,-51,-37; /M: SY='R'; M= 6,-45, 18, 42, -2,-37,-24,-46, 31,-42,-36, 7, -6,-13, 48,-13,-27,-40,-45,-32; /M: SY='K'; M=-31,-47, 11, 19,-43,-40, 34,-41, 49, -8,-28,-19,-35, 45, 34,-24, 0,-39,-46,-30; /M: SY='H'; M=-38,-50,-22,-22,-36,-40,132,-55,-27,-37,-22,-11,-39,-16,-21,-27,-37,-54,-72, -5; /M: SY='R'; M=-33,-49,-30, 7, -5,-44,-24,-16, 19,-19,-29,-26,-41, 4, 84,-10,-31,-36,-42,-28; /M: SY='R'; M= 3,-41,-23, 3,-42,-30,-24,-40, 31,-14,-31, 29,-36, 25, 41, 35,-20,-37,-47,-34; /M: SY='F'; M=-42,-40,-52,-46,100,-51,-35,-18, 0, 5,-18,-43,-52,-50,-37,-41,-35,-23,-13, 9; /I: I=-15; MD=-77; /M: SY='A'; M= 68,-34,-41,-34,-40,-27,-42,-26,-36, -5,-27,-35,-40,-33,-40,-16, 7, 6,-49,-40; D=-15; /I: I=-15; MI=-77; IM=-77; DM=-77; /M: SY='M'; M=-11, 24, 1, 33,-37,-38,-28, 4, 27,-14, 37, -7,-34,-17, 10, 15, 8,-26,-48,-33; /M: SY='N'; M=-30,-41, 33, 24,-48,-28,-18,-45, 21,-47,-37, 74,-35, 31,-18,-17, 12,-44,-56,-38; /M: SY='D'; M= -1,-42, 68, 9,-50,-27,-23,-47,-14,-49,-43, 40, 15,-20,-30, 32, -6,-42,-59,-39; /M: SY='E'; M= 17,-41, 24, 38,-42,-32, 14,-24, 1,-14,-32, 21,-35,-15, 24, 21,-22,-34,-50,-35; /M: SY='N'; M=-32,-39,-14,-26, 13,-27, 42,-39, -7,-22,-31, 84,-42, 5, 9, -1,-21,-41,-48, -1; /M: SY='W'; M=-41,-48,-49,-42, 75,-47,-25,-25,-38,-19,-22,-44,-51, 10,-36,-39,-38,-31, 93, 76; /M: SY='Q'; M= 33,-41,-30, 7,-38,-35,-32, 15, 36, -6,-22,-28,-36, 45,-18,-22,-25, 6,-43,-33; /M: SY='D'; M= 16, 34, 37, 20,-45, 2, 23,-37, 13,-37, 9,-20,-36, 29, -8,-14,-27, -5,-51,-34; /M: SY='I'; M=-31,-39,-51,-46,-15,-54,-44, 52,-45, 50, -3,-45,-46,-41,-45,-39, 5, 29,-44,-25; /M: SY='D'; M=-34,-47, 97, -3,-49,-33,-23,-46,-25,-12,-43, -7,-36,-24,-33, 3,-24,-45,-67,-37; /M: SY='D'; M= 1,-40, 55, 6,-47,-28,-26,-44, -2,-45,-39, 1,-33, -1, 12, 45, 23,-37,-55,-36; /M: SY='L'; M=-36,-39,-54,-47, 46,-54,-38, 26,-46, 60, 23,-49,-51,-42,-44,-44,-31, 0,-32,-13; /M: SY='I'; M=-12,-43,-51,-48, 10, -2,-45, 67,-45, 25, 31,-42,-44,-41,-46,-38,-29, 11,-40,-23; /M: SY='S'; M= 23,-40, 16, 27,-19, 5,-28,-25,-24, -8, 1, -5,-35, 30,-29, 34,-21,-31,-46,-33; /M: SY='Q'; M=-26, 18,-25, 5,-41,-36, 36,-38, 3,-15, -2, -9,-36, 54, 33, 25, 24,-35,-49,-29; /M: SY='L'; M=-29,-39,-48,-44, 25,-19,-39, 34,-42, 45, 26,-41,-46,-38,-43, 11,-26, 16,-39,-20; /M: SY='Q'; M= 16,-42, 4, -9,-33, -2,-26,-20, 10, -9,-27,-23,-38, 41, 20, 14, -2,-13,-39, 22; /M: SY='F'; M=-32, 19, 5, 0, 51,-41, 14,-32,-17,-19,-27, -4,-42, 30, 45, -3, -5,-14,-36,-16; /M: SY='D'; M=-20,-47, 46, 19, -6,-36, 4,-37, 10,-39, -7, 5, 38, 6, 14, 0,-25, -8,-47, -8; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
| Total number of hits | 12 in 12 different sequences |
| Number of true positive hits | 12 in 12 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | window20 |
| Author [info] | N_Hulo |
| Feature key [info] | ZN_FING |
| Feature description [info] | DBF4-type |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
12 sequences
CHIF_DROME (Q9NK54), DBF4A_CRIGR (Q99MU0), DBF4A_HUMAN (Q9UBU7), DBF4A_MOUSE (Q9QZ41), DBF4A_XENLA (Q7ZZH7), DBF4A_XENTR (Q28FY7), DBF4B_HUMAN (Q8NFT6), DBF4B_XENLA (Q283Q6), DBF4_YEAST (P32325), HIM1_SCHPO (O59836), SPO6_SCHPO (Q9Y7J1), ZDBF2_HUMAN (Q9HCK1)» more
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| PDB [Detailed view] |
11 PDB
4F99; 4F9A; 4F9B; 4F9C; 6YA6; 6YA7; 6YA8; 7P5Z; 7PT6; 7PT7; 7V3V |