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| Entry: PS51269 |
General information about the entry
| Entry name [info] | COMM |
| Accession [info] | PS51269 |
| Entry type [info] | MATRIX |
| Date [info] |
01-NOV-2006 CREATED;
10-MAY-2017 DATA UPDATE; 02-JUN-2021 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51269 |
| Associated ProRule [info] | PRU00602 |
Name and characterization of the entry
| Description [info] | COMM domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=70; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=65; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2327802; R2=0.0055337; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=9697.8144531; R2=2.2880867; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=1133; H_SCORE=12290; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=772; H_SCORE=11464; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-27; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='H'; M= -23, -77, -55, -19, -75, -12, 76, -44, 44, -71, -44, 5, -68, 67, 33, -4, -21, -35, -78, -29; /M: SY='L'; M= -66, -71, -81, -40, -7, -85, -66, 36, -75, 72, 13, -80, -81, -70, -74, -74, -62, 2, -64, 38; /M: SY='H'; M= -13, -73, -1, 26, -66, -72, 49, 31, -11, -28, -54, -27, -68, 6, 15, 1, 29, 27, -82, -60; /M: SY='D'; M= -60, -75, 91, -24, -81, 15, -55, -81, -13, -82, -76, 43, -67, -53, -36, 23, 2, -77, -91, -49; /M: SY='M'; M= -22, -69, -81, -39, 32, -81, -70, 17, -36, 46, 71, -76, -77, -69, -71, -69, -40, 46, -71, -50; /M: SY='E'; M= -6, -75, 45, 51, -81, 14, -56, -80, 10, -78, -71, 12, -64, 35, -5, 38, -54, -74, -82, -69; /M: SY='W'; M= -75, -15,-102, -80, -14, -74,-102, -73, -72, -70, -73, -95, -80, -72, -76, -82, -87, -87, 177, -27; /M: SY='R'; M= -64, -81, -60, -48, -77, -73, -52, -81, 33, -75, -64, -4, -72, 43, 101, -33, -34, -75, -76, -63; /M: SY='V'; M= -62, -70, -82, -40, 40, -85, -74, 29, -75, 56, -37, -79, -80, -29, -75, -72, -59, 56, -70, -50; /M: SY='D'; M= -25, -12, 82, 22, -81, 23, 3, -79, -12, -79, -73, 52, -67, -29, -17, -53, -57, -30, -90, -70; /I: I=-5; MD=-13; /M: SY='Y'; M= -30, 10, -76, -35, -21, -15, -65, 14, -71, 22, 31, -32, -78, -23, -72, -22, -58, 55, -66, 56; D=-5; /I: I=-5; MD=-13; /M: SY='Q'; M= 20, 0, -1, -19, -34, -68, -11, -3, 32, -41, -58, -54, -68, 78, -19, -51, 31, -12, -78, -63; D=-5; /I: I=-5; MI=0; MD=-13; IM=0; DM=-13; /M: SY='M'; M= -28, -68, -74, -71, -24, -74, -70, 40, -69, 41, 42, -66, -73, -65, -71, 35, 29, 27, -77, -57; /M: SY='S'; M= 40, -67, -59, -54, -75, 6, -60, -73, 25, -74, -66, -50, -65, 26, -27, 76, -46, -65, -76, -24; /M: SY='S'; M= -9, -65, -27, -56, -72, -54, 7, -68, -33, -45, -65, 13, -64, -13, -36, 88, 40, -35, -84, -65; /M: SY='S'; M= -52, -71, 35, -30, -77, -35, 17, -78, -3, -77, -69, 18, -67, -17, 51, 75, -26, -72, -84, -65; /M: SY='H'; M= 5, 2, 1, 20, -37, -42, 58, -37, 6, -18, -60, -41, -32, 12, -28, 44, 30, -63, -78, 0; /M: SY='Q'; M= -23, 26, -68, -40, -31, -43, -15, 22, -62, 44, 0, 16, -74, 46, -22, 9, -12, 7, -77, -59; /M: SY='R'; M= 29, -73, 6, 15, -73, -64, 35, -71, 24, -28, -62, -52, -66, 37, 40, 28, 2, -46, -78, -33; /M: SY='K'; M= -36, -10, -35, 3, -76, -68, 22, -71, 57, -72, -63, -7, -26, 51, 49, 9, 9, -12, -78, -63; /M: SY='M'; M= -32, -72, -23, 5, -58, -73, -25, 19, -62, 27, 47, -30, -24, 43, -64, 24, -40, 35, -77, -23; /I: I=-26; MI=0; MD=-65; IM=0; DM=-65; /M: SY='N'; M= -3, 7, -23, -1, -69, 27, 33, -13, 27, -3, -58, 50, -69, 37, -40, -30, -34, -38, -78, -14; /M: SY='S'; M= -23, -71, -28, 14, -71, -62, -23, -65, 25, -49, 12, 8, -66, 35, 19, 58, 19, -9, -78, -14; /M: SY='P'; M= -9, -17, -16, -58, -76, -69, -70, 13, -65, -33, -14, -70, 112, -66, -75, -34, -34, -32, -79, -76; /M: SY='F'; M= -11, -9, -44, -66, 35, -17, -21, -11, -41, 11, 22, -29, -25, 11, -39, 22, 23, 29, -69, 14; /M: SY='V'; M= 33, 23, -76, -73, 3, -35, -70, 33, -71, 14, -10, -26, -76, -69, -73, -37, -56, 50, -69, 34; /M: SY='H'; M= -14, -19, -65, -35, -30, -73, 56, 8, -35, 33, -46, 3, -73, 51, -62, -27, 17, 28, -77, -14; /I: I=-28; MI=0; MD=-71; IM=0; DM=-71; /M: SY='M'; M= -63, -70, -84, -77, -34, -84, -70, 47, -75, 60, 77, -78, -78, -70, -74, -73, -59, 30, -74, -54; /M: SY='Q'; M= -40, -76, -29, 47, -78, -66, 34, -75, 42, -63, -5, 33, -64, 68, -2, 7, 1, -72, -79, -42; /M: SY='L'; M= -67, -69, -85, -77, 16, -84, -66, -20, -76, 82, 64, -81, -82, -70, -73, -76, -63, -40, -69, -49; /M: SY='K'; M= -59, -76, 3, 35, -72, 13, 35, -42, 53, -71, -27, 23, -25, 6, -19, -5, -10, -7, 10, -13; /M: SY='V'; M= -58, -68, -41, -71, -20, -78, -73, 30, -69, 40, -41, -10, -75, -69, -42, -9, 38, 57, -79, -58; /M: SY='Q'; M= 13, -71, -12, 3, -2, 13, -2, -63, 16, -24, -26, 6, -68, 41, -5, 30, -5, 3, -76, -62; /M: SY='N'; M= -3, -74, 46, 10, -80, -24, -54, -76, 36, -77, -68, 57, -11, 35, 14, 5, -17, -47, -83, -68; /M: SY='N'; M= -12, -73, -14, 29, -73, 44, 17, -77, -4, -75, -15, 47, -16, -3, -16, 20, 1, -73, -77, 8; /I: I=-8; MD=-20; /M: SY='D'; M= -70,-104, 53, -12,-106, -24, -84,-100, -50, -60, -97, -15, 38, -80, -89, -7, -80, -65,-112, -97; D=-8; /I: I=-8; MI=0; MD=-20; IM=0; DM=-20; /M: SY='N'; M= -45, -92, -41, -23, -97, 24, -79, -97, -49, -57, -89, 31, -89, -15, -12, 25, -4, -92,-103, -91; D=-8; /I: I=-8; DM=-20; /M: SY='Q'; M= -41, -87, -62, 19, -89, 29, -68, -48, 3, -64, -75, 35, 21, 45, -32, -61, -4, -47, -89, -80; D=-8; /I: I=-8; DM=-20; /M: SY='Q'; M= -36, 7, -30, 29, -86, -73, -2, -50, 25, -81, -37, 18, -30, 43, 13, 27, -22, -55, -89, -74; D=-8; /I: I=-8; DM=-20; /M: SY='V'; M= -16, -78, -22, -32, -67, -55, 0, 14, -19, -22, -17, -8, -79, -25, -8, 23, 6, 31, -84, 11; D=-8; /I: I=-8; DM=-20; /M: SY='E'; M= -58, -76, -26, 54, -76, -69, -29, -35, 25, -52, -67, -16, 17, 29, -16, 38, 27, -44, -80, -27; D=-8; /I: I=-8; DM=-20; /M: SY='P'; M= 0, -73, 25, 4, 14, -28, 11, -11, 13, -66, -26, 12, 47, -56, -34, -1, 40, -30, -76, -15; /M: SY='H'; M= -61, -73, -34, -66, -54, -36, 61, 43, 9, 20, -9, -64, -74, -9, -27, -41, -28, 50, -77, -2; /M: SY='C'; M= -36, 35, -59, -6, -12, -67, -16, -17, -23, -17, -23, 31, -28, 30, 9, 35, 27, 1, -72, 32; /M: SY='F'; M= -44, -70, -84, -78, 82, -46, -68, 1, -75, 35, 67, -75, -80, -74, -73, -30, -61, 20, 5, -37; /M: SY='E'; M= -36, -77, -8, 89, -81, -69, -54, -76, -25, -74, -68, 4, -60, 50, -52, 19, -11, -27, -81, -70; /M: SY='M'; M= -63, 71, -80, -75, 53, -79, -69, -7, -72, 34, 73, -71, -36, -72, -73, -65, 28, 13, -70, -48; /M: SY='S'; M= -54, -69, 55, -51, -77, -33, -57, -73, -56, -77, -70, 53, 33, -54, -63, 57, 52, -68, -89, -70; /M: SY='M'; M= 18, -73, -65, 8, -61, -71, 28, 21, 15, 24, 34, -26, 31, -23, -16, -21, -18, 0, -77, -61; /M: SY='E'; M= 28, 9, 25, 58, -79, -43, -60, -70, -1, -72, -16, -56, 46, 22, -57, -2, -12, -17, -81, -71; /M: SY='Q'; M= -58, -18, -26, 56, -79, -68, -55, -73, 51, -72, -7, 1, -27, 72, -43, -1, 18, -44, -78, -66; /M: SY='F'; M= -69, -70, -85, -79, 78, -84, -69, -5, -78, 66, 2, -80, -30, -76, -75, -75, -63, -4, -59, -38; /M: SY='Q'; M= -37, -76, -1, -48, -26, -68, 22, -60, 5, 8, -4, 39, -71, 87, -1, -45, -30, -12, -72, 22; /M: SY='H'; M= -19, -73, 26, 46, -70, -45, 49, -63, -25, -8, -59, 19, -66, 38, -37, 21, 6, 6, -82, -28; /M: SY='F'; M= -67, -70, -85, -78, 71, -84, -68, -9, -77, 65, 51, -80, -82, -74, -74, -75, -63, 2, -61, -40; /M: SY='Y'; M= -64, -14, -75, -70, -45, -81, 3, 43, -33, 38, -42, -70, -78, -62, 35, -24, -20, 21, -64, 59; /M: SY='N'; M= -3, -74, 12, -14, -21, 3, 40, -73, 34, -72, -63, 61, -69, 30, -2, -23, -26, -45, -72, 37; /M: SY='Q'; M= -31, -76, -10, 50, -78, -6, -55, -39, 44, -50, -64, 26, -64, 60, -8, -1, -12, -18, -78, -67; /M: SY='L'; M= -43, -12, -83, -76, 8, -82, -68, 13, -75, 72, 61, -78, -80, -70, -74, -39, -34, 6, -71, -52; /M: SY='E'; M= 24, -73, -48, 62, -33, -14, -58, -75, 55, -74, -67, -24, -62, -1, -15, 22, -31, -45, -76, -67; /M: SY='Q'; M= -20, -77, 38, 42, -74, -69, -7, -70, 9, 3, -60, -51, -66, 63, 34, 9, -5, -68, -79, -64; /M: SY='A'; M= 61, -68, -76, -70, -60, -25, -75, 60, -37, -10, 19, -69, -71, -66, -72, -56, -55, 27, -76, -63; /M: SY='Q'; M= 0, -74, -58, 29, -65, -70, -19, -33, 6, 35, -51, -1, -70, 59, 30, 6, -58, -18, -76, -62; /M: SY='K'; M= 29, -72, 30, 35, -74, -40, -60, -42, 46, -30, -63, -4, -65, -8, 4, -9, 14, -12, -80, -67; /M: SY='E'; M= -32, -18, -13, 57, -70, -67, 13, -46, -29, -19, 36, -4, -65, 41, -57, 43, -28, 19, -81, -64; /M: SY='M'; M= -61, 30, -81, -74, -49, -79, -16, 32, -42, 50, 90, -73, -77, -66, -71, -5, -58, 18, -76, -55; /M: SY='E'; M= -19, -74, 47, 54, -77, -64, -54, -39, 17, -29, -66, 39, -64, 30, -13, 18, 0, -69, -83, -68; /M: SY='Q'; M= 32, 29, 13, -34, -33, -42, -60, -70, -10, -70, -64, -28, -22, 51, 16, 32, 46, -63, -78, -25; /M: SY='L'; M= -1, -70, -74, -71, 9, -52, -19, 5, -68, 57, 27, 18, -78, -20, -24, -65, -23, 19, -70, 8; /M: SY='T'; M= 27, -37, -53, 29, -70, -8, 34, -47, 2, -35, 0, 36, -66, -10, -6, 3, 39, -20, -80, -30; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
| Total number of hits | 42 in 42 different sequences |
| Number of true positive hits | 42 in 42 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Feature key [info] | DOMAIN |
| Feature description [info] | COMM |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
42 sequences
COMD1_BOVIN (Q2M2T5 ), COMD1_CANLF (Q8WMD0 ), COMD1_DICDI (Q54DR0 ), COMD1_HUMAN (Q8N668 ), COMD1_MOUSE (Q8K4M5 ), COMD2_DICDI (Q54P14 ), COMD2_HUMAN (Q86X83 ), COMD2_MOUSE (Q8BXC6 ), COMD2_PONAB (Q5R610 ), COMD3_BOVIN (Q3SZ76 ), COMD3_DICDI (Q54QK4 ), COMD3_HUMAN (Q9UBI1 ), COMD3_MOUSE (Q63829 ), COMD3_RAT (Q6P9U3 ), COMD4_BOVIN (Q5E9V6 ), COMD4_DICDI (Q550I8 ), COMD4_HUMAN (Q9H0A8 ), COMD4_MOUSE (Q9CQ02 ), COMD5_BOVIN (Q5E9K1 ), COMD5_DICDI (Q86IW8 ), COMD5_HUMAN (Q9GZQ3 ), COMD5_MOUSE (Q8R395 ), COMD5_RAT (Q9ERR2 ), COMD6_BOVIN (Q2KIY0 ), COMD6_DICDI (Q54MA5 ), COMD6_HUMAN (Q7Z4G1 ), COMD6_MOUSE (Q3V4B5 ), COMD6_XENLA (Q05AV1 ), COMD6_XENTR (Q28HC7 ), COMD7_BOVIN (Q3MHX1 ), COMD7_DICDI (Q86I14 ), COMD7_HUMAN (Q86VX2 ), COMD7_MOUSE (Q8BG94 ), COMD8_DICDI (Q54CU8 ), COMD8_HUMAN (Q9NX08 ), COMD8_MOUSE (Q9CZG3 ), COMD9_BOVIN (Q2TBN5 ), COMD9_HUMAN (Q9P000 ), COMD9_MOUSE (Q8K2Q0 ), COMDA_DICDI (Q554G3 ), COMDA_HUMAN (Q9Y6G5 ), COMDA_MOUSE (Q8JZY2 )» more
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| PDB [Detailed view] |
1 PDB
6BP6 |
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