PROSITE entry PS51292
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General information about the entry
| Entry name [info] | ZF_RING_CH |
| Accession [info] | PS51292 |
| Entry type [info] | MATRIX |
| Date [info] |
01-FEB-2007 CREATED;
10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51292 |
| Associated ProRule [info] | PRU00623 |
Name and characterization of the entry
| Description [info] | Zinc finger RING-CH-type profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=62; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=57; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.5666564; R2=0.0068634; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=8548.0878906; R2=2.8060076; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=1302; H_SCORE=12202; N_SCORE=11.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=574; H_SCORE=10159; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-22; D=-120; I=-120; B1=-300; E1=-300; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='M'; M= -12, -58, -10, 26, -10, 1, -7, -17, 4, -4, 35, 17, -25, 11, -4, 29, -9, -18, -63, -47; /M: SY='E'; M= -10, -3, 22, 26, -29, -17, -14, -12, 21, -34, -14, 19, -53, 6, -21, 18, 17, 1, -63, 2; /M: SY='S'; M= 2, -58, 20, 17, -1, 6, 0, -7, 9, -34, -48, 6, -24, 17, -21, 36, -10, -8, -64, -48; /M: SY='E'; M= -20, -17, 7, 39, -21, -10, -44, -23, 9, -5, -15, 23, -31, 25, -8, 19, 5, -10, -65, -50; /M: SY='E'; M= -2, -59, 39, 45, -61, 10, -45, -58, -6, -59, -54, -18, -7, 10, -31, 35, 13, -16, -66, -14; /M: SY='E'; M= 11, -58, 3, 40, -58, 32, -2, -41, -1, -54, 22, -14, -14, -38, -16, 14, 11, -9, -64, -16; /M: SY='R'; M= 8, -13, 17, -18, -58, -34, -9, 7, 33, -18, -19, 10, 21, 9, 39, -12, -6, -34, -65, -51; /M: SY='I'; M= -35, 29, -15, 18, 5, -21, -6, 41, -45, -18, -11, -47, -57, 38, -9, 12, -29, 25, -61, -14; /M: SY='C'; M= -47, 150, -67, -67, -57, -63, -67, -64, -63, -55, -55, -53, -78, -71, -69, -50, -47, -52, -87, -68; /M: SY='W'; M= -54, -71, -53, -40, -53, -61, -45, -66, 35, -61, -52, -46, -60, -30, 95, -50, -54, -64, 102, -40; /M: SY='I'; M= -51, -63, -71, -69, 19, -75, -66, 95, -64, -19, -1, -62, -61, -62, -67, -59, -45, 10, -54, 7; /M: SY='C'; M= -47, 150, -67, -67, -57, -63, -67, -64, -63, -55, -55, -53, -78, -71, -69, -50, -47, -52, -87, -68; /M: SY='H'; M= -53, -62, -52, -29, 42, -18, 67, -30, 2, 19, 22, -15, -61, 17, 38, -50, -50, -47, -50, 33; /M: SY='E'; M= -23, 46, 35, 55, -11, -10, -45, -54, -19, -9, -2, -28, -52, 24, -45, 12, 3, -33, -8, -51; /M: SY='E'; M= -16, -61, 13, 51, -65, 44, -15, -64, -15, -45, -55, -11, 16, 10, -46, 16, 19, -58, -66, -57; /I: I=-15; MD=-33; /M: SY='D'; M= -3, 11, 45, 42, -60, 11, -47, -61, -16, -32, -23, -40, -10, -40, -34, 21, 0, -44, -67, 6; D=-15; /I: I=-15; MD=-33; /M: SY='S'; M= -53, -82, 21, 16, -13, -31, -67, -51, -63, -80, -77, -6, -74, -3, -69, 22, -1, -76, -89, -72; D=-15; /I: I=-15; MI=0; MD=-33; IM=0; DM=-33; /M: SY='W'; M= -26, -67, 11, 34, -62, -26, -51, -39, 8, -18, 6, 20, 19, -25, -15, 22, -46, -31, 40, -56; D=-15; /I: I=-15; DM=-33; /M: SY='D'; M= -29, -15, 39, 20, -64, 21, -11, -26, -20, -35, -10, 19, 19, -20, -28, 21, 4, -41, -72, -58; D=-15; /I: I=-15; DM=-33; /M: SY='N'; M= -16, -4, 35, 26, -59, 31, 17, -57, -31, -22, -52, 53, -19, -39, 0, 6, -42, -17, -69, -20; /M: SY='P'; M= -28, -64, 13, 9, -58, -55, 15, -19, 19, -3, -46, -5, 70, 6, 3, -2, -1, -18, -66, -53; /M: SY='L'; M= -51, -12, -67, -38, 35, -44, -57, 26, -38, 60, 19, -62, -66, -56, -32, -32, -26, 2, 42, -34; /M: SY='I'; M= -34, -13, -34, 10, 19, -40, -57, 65, -2, -10, -32, -52, -58, -22, 10, -31, -6, 20, -58, -20; /M: SY='H'; M= -20, -22, -41, -7, -53, -31, 55, -30, 3, -8, 0, 35, -55, -1, 33, 42, 6, -37, -66, -13; /M: SY='P'; M= -31, -73, -52, -13, -26, 1, -53, -55, -48, -45, -52, -56, 110, -50, -28, -48, -46, -28, -59, 9; /M: SY='C'; M= -47, 150, -67, -67, -57, -63, -67, -64, -63, -55, -55, -53, -78, -71, -69, -50, -47, -52, -87, -68; /M: SY='R'; M= 10, -13, 6, -11, -55, -30, -41, -37, 32, -13, 3, 31, -56, 25, 49, 2, -43, -52, -60, 5; /M: SY='C'; M= -47, 150, -67, -67, -57, -63, -67, -64, -63, -55, -55, -53, -78, -71, -69, -50, -47, -52, -87, -68; /M: SY='K'; M= -21, -59, 0, -18, -59, -51,-100, -37, 60, -45, -50, -22, -52, 4, 40, 38, 25, -31, -63, -21; /I: I=-31; MD=-65; /M: SY='G'; M= -21, -63, -50, -61, -69, 94, -56,-100, -53, -72, -61, 2, -56, -52, -15, -36, -54, -70, -62, -64; D=-31; /I: I=-31; MI=-65; MD=-65; IM=-65; DM=-65; /M: SY='S'; M= -35, -54, 23, 16, -62, -10,-100, -60, -43, -62, -57, -33, -14, -38, -49, 74, 49, -52, -72, -55; D=-31; /I: I=-31; DM=-65; /M: SY='M'; M= -23, -14, -63, -57, -14, -65,-100, 38, -55, 42, 55, -5, -63, 17, -27, -37, -25, 26, -62, -43; D=-31; /I: I=-31; DM=-65; /M: SY='K'; M= 16, -61, -24, -23, -58, 24,-200, -60, 54, -27, -48, -24, -53, 48, 20, -4, -34, -56, -57, 7; /M: SY='Y'; M= -34, -64, -36, -56, 33, -62,-100, 2, -13, 8, -35, -26, -65, -14, -50, -23, -33, -17, 74, 91; /M: SY='V'; M= 31, -10, -66, -60, -26, -61,-100, 45, -59, -19, -30, -60, -61, -59, -61, -47, -24, 73, -67, -48; /M: SY='H'; M= -55, -67, -39, -39, -54, -57, 144, -72, -44, -54, -40, -29, -56, -33, -38, -45, -54, -72, -89, -23; /M: SY='Q'; M= -35, -64, -38, 45, -27, -21, 11, -40, 8, -23, -46, -3, -2, 56, 42, 1, -24, -8, -63, -49; /M: SY='E'; M= -12, -62, 18, 45, -61, -12, -4, -60, 30, -59, 2, 8, -11, 27, 16, 24, -27, -37, -63, -10; /M: SY='C'; M= -47, 150, -67, -67, -57, -63, -67, -64, -63, -55, -55, -53, -78, -71, -69, -50, -47, -52, -87, -68; /M: SY='L'; M= -4, -55, -69, -62, -12, -68, -57, 19, -62, 75, -1, -66, -67, -57, -61, -58, -47, 9, -58, -40; /M: SY='E'; M= -14, -62, 13, 42, -4, -55, -42, -6, 40, -40, 21, 16, -52, 40, 7, -14, -28, -21, -61, -18; /M: SY='R'; M= 0, -60, -15, 26, -57, -54, 29, -54, 35, -27, 28, -1, -52, 27, 42, -9, 15, -33, -63, -17; /M: SY='W'; M= -59, -83, -32, -10, -29, -60, -75, -59, -53, -40, -57, -72, -63, 10, -57, -63, -68, -71, 167, 6; /M: SY='I'; M= -34, 22, -68, -62, 37, -70, -59, 62, -55, 28, 21, -60, -64, -23, 7, -56, -29, 19, -55, -36; /M: SY='N'; M= -26, -58, -10, 13, -25, -27, -19, 16, -5, -4, -19, 39, -55, -13, 27, 27, 13, -9, -64, -18; /I: I=-36; MD=-77; /M: SY='T'; M= -13, -12, -20, 15, -21, -42, 12, -9, -4, -15, 28, -6, -55, 27, 7, 16, 29, 11, -63, -5; D=-36; /I: I=-36; MI=-77; IM=-77; DM=-77; /M: SY='K'; M= -26, -59, -20, -16, -64, -10, -42, -63, 53, -62, -52, 22, -52, 40, 37, 43, 6, -58, -64, -52; /I: I=-16; MI=0; MD=-34; IM=0; DM=-34; /M: SY='G'; M= -9, -62, 18, -15, -30, 42, 18, -62, 20, -39, -52, 20, -27, 33, 32, -5, -29, -41, -64, -51; /M: SY='N'; M= -44, -28, -5, 16, -8, -28, -6, -2, 15, -41, -49, 54, -18, 1, 20, 28, 22, -37, -66, -49; /M: SY='T'; M= 5, -56, -49, -31, -45, -55, -48, 20, 10, 8, 19, 26, -28, -21, 10, 2, 33, 5, 1, 1; /M: SY='K'; M= -5, 0, -20, -12, -36, -55, 37, -13, 41, -44, -8, -12, -54, 26, 38, 1, 24, -21, -61, 5; /M: SY='C'; M= -47, 150, -67, -67, -57, -63, -67, -64, -63, -55, -55, -53, -78, -71, -69, -50, -47, -52, -87, -68; /M: SY='E'; M= -22, -66, 22, 84, -68, -58, -42, -38, 11, -61, -56, -40, 22, 5, 5, -22, -18, -59, -66, -57; /M: SY='I'; M= -47, -60, -61, -37, -1, -66, -57, 68, -54, 23, 18, -27, -60, 36, -56, -4, -27, 22, -59, -41; /M: SY='C'; M= -47, 150, -67, -67, -57, -63, -67, -64, -63, -55, -55, -53, -78, -71, -69, -50, -47, -52, -87, -68; /M: SY='H'; M= -44, -63, -40, -21, -62, 37, 51, -65, 44, -38, -50, 33, -54, 49, 14, 4, -45, -62, -63, -23; /M: SY='T'; M= 6, -5, -14, 14, 25, -31, 42, -46, -12, -47, -21, -41, -54, 20, -29, 7, 43, 4, -55, 31; /M: SY='P'; M= -13, -61, -24, 29, -30, -55, -48, -29, 33, -51, 1, -26, 51, 22, 2, -3, 20, 15, -64, -52; /M: SY='Y'; M= -4, -13, -62, -61, 71, -63, -35, -38, -56, -21, -36, -59, -69, -55, -54, -52, -50, -17, -22, 103; /M: SY='Q'; M= -34, -60, -15, 4, -58, -52, -12, -25, 21, -14, -45, 39, -34, 48, 45, 18, 7, -14, -66, -50; /M: SY='M'; M= -49, -23, -57, -57, 29, -61, -51, 34, -30, 26, 58, 37, 0, -52, -33, -38, -7, 16, 3, -15; /M: SY='E'; M= -3, -59, -1, 34, -55, -38, 9, 9, 29, -25, -44, 17, -22, -11, 6, -2, 4, 19, -67, -51; /I: E1=0; IE=-255; DE=-255;» more |
Post-processing [info]
| COMPETES_HIT_WITH | PS50089 |
Numerical results [info]
| Total number of hits | 59 in 59 different sequences |
| Number of true positive hits | 59 in 59 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 4 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 93.65 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | N_Hulo |
| Feature key [info] | ZN_FING |
| Feature description [info] | RING-CH-type |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
59 sequences
DOA10_SCHPO (O60103), DOA10_YEAST (P40318), LAP_LSDVN (Q91T40), LAP_MYXVL (Q997C2), LAP_RFVKA (Q9Q8T2), LAP_SWPVK (P32225), LAP_YLDV(Q9DHV7), LAP_YMTV5 (Q6TV02), MARC3_CAEEL (Q93227), MARH1_HUMAN (Q8TCQ1), MARH1_MOUSE (Q6NZQ8), MARH2_BOVIN (Q32L65), MARH2_DANRE (Q1LVZ2), MARH2_HUMAN (Q9P0N8), MARH2_MOUSE (Q99M02), MARH2_RAT (Q5I0I2), MARH2_XENLA (Q5PQ35), MARH2_XENTR (Q28EX7), MARH3_BOVIN (A0JN69), MARH3_HUMAN (Q86UD3), MARH3_MOUSE (Q8BRX9), MARH3_RAT (Q5XIE5), MARH3_XENLA (Q0IH10), MARH3_XENTR (Q68FA7), MARH4_DANRE (Q0P496), MARH4_HUMAN (Q9P2E8), MARH4_MOUSE (Q80TE3), MARH5_BOVIN (Q3ZC24), MARH5_CHICK (Q5ZJ41), MARH5_CHLAE (Q0X0A5), MARH5_DANRE (Q6NYK8), MARH5_HUMAN (Q9NX47), MARH5_MOUSE (Q3KNM2), MARH5_XENLA (Q6GM44), MARH6_HUMAN (O60337), MARH6_MOUSE (Q6ZQ89), MARH6_PONAB (Q5R9W1), MARH7_HUMAN (Q9H992), MARH7_MOUSE (Q9WV66), MARH7_PONAB (Q5R9W2), MARH7_RAT (Q5XI50), MARH8_BOVIN (Q0VD59), MARH8_HUMAN (Q5T0T0), MARH8_MOUSE (Q9DBD2), MARH8_XENLA (Q5XH39), MARH8_XENTR (Q28IK8), MARH9_HUMAN (Q86YJ5), MARH9_MOUSE (Q3TZ87), MARHA_HUMAN (Q8NA82), MARHA_RAT (Q5XIV2), MARHB_HUMAN (A6NNE9), MARHB_MOUSE (Q8CBH7), MARHB_RAT (A6P320), MIR1_HHV8P (P90495), MIR1_MHV68 (O41933), MIR2_HHV8P (P90489), SUD1_ARATH (F4JKK0), VIE1_BHV4D (P27426), YG87_SCHPO (O74371)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
4 sequences
FANCL_DROME (Q8T913), ORTH2_ARATH (Q8VYZ0), ORTH4_ARATH (Q9C8E1), ORTH5_ARATH (Q680I0)» more |
| PDB [Detailed view] |
7 PDB
1VYX; 2D8S; 2M6M; 3K1L; 8PD0; 8PDA; 8TQM |