General rule information
[?]
Accession |
PRU00623 |
Dates |
8-MAY-2008 (Created) 14-MAY-2022 (Last updated, Version 7) |
Predictors |
PROSITE; PS51292; ZF_RING_CH
|
Name |
Zinc finger RING-CH-type |
Function |
The RING-CH-type is an E3 ligase mainly found in proteins associated to membranes. |
Propagated annotation
[?]
Domain |
The RING-CH-type zinc finger domain is required for E3 ligase activity. |
case (<Feature:PS51292:9=[CH]> and <Feature:PS51292:12=[CH]> and <Feature:PS51292:36=[CH]> and <Feature:PS51292:39=[CH]>) or (<Feature:PS51292:26=[CH]> and <Feature:PS51292:28=[CH]> and <Feature:PS51292:52=[CH]> and <Feature:PS51292:55=[CH]>)
end case
case (<Feature:PS51292:9=[C]> and <Feature:PS51292:12=[C]> and <Feature:PS51292:36=[H]> and <Feature:PS51292:39=[C]>) and (<Feature:PS51292:26=[C]> and <Feature:PS51292:28=[C]> and <Feature:PS51292:52=[C]> and <Feature:PS51292:55=[C]>)
From: PS51292 |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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ZN_FING
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from
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to
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RING-CH-type #
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else case (<Feature:PS51292:9=[CH]> and <Feature:PS51292:12=[CH]> and <Feature:PS51292:36=[CH]> and <Feature:PS51292:39=[CH]>) and (<Feature:PS51292:26=[CH]> and <Feature:PS51292:28=[CH]> and <Feature:PS51292:52=[CH]> and <Feature:PS51292:55=[CH]>)
ZN_FING
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from
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to
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RING-CH-type #; atypical
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else
ZN_FING
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from
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to
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RING-CH-type #; degenerate
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end case
BINDING
|
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9
|
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9
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/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#1
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[CH]
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1
|
BINDING
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12
|
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12
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/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#1
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[CH]
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1
|
BINDING
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26
|
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26
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/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#2
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[CH]
|
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2
|
BINDING
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28
|
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28
|
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/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#2
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[CH]
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2
|
BINDING
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36
|
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36
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/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#1
|
|
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[CH]
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1
|
BINDING
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39
|
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39
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/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#1
|
|
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|
[CH]
|
|
1
|
BINDING
|
|
52
|
|
52
|
|
/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#2
|
|
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[CH]
|
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2
|
BINDING
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55
|
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55
|
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/ligand="Zn(2+)" /ligand_id="29105" /ligand_label="#2
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[CH]
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2
|
Additional information
[?]
Size range |
50-85 amino acids |
Related rules |
None |
Repeats |
1 |
Topology |
Undefined |
Example |
Q8TCQ1 (MARH1_HUMAN) |
Scope |
Eukaryota
Viruses |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
[?]