ProRule PRU00623

Accession	PRU00623
Dates	8-MAY-2008 (Created) 19-NOV-2022 (Last updated, Version 8)
Data class	Domain;
Predictors	PROSITE; PS51292; ZF_RING_CH
Name	Zinc finger RING-CH-type
Function	The RING-CH-type is an E3 ligase mainly found in proteins associated to membranes.
Scope(s)	Eukaryota Viruses
Example(s)	Q8TCQ1 (MARH1_HUMAN);

From: PS51292
Key	From	To	Description	Tag	Condition	FTGroup
case (<Feature:PS51292:9=[C]> and <Feature:PS51292:12=[C]> and <Feature:PS51292:36=[H]> and <Feature:PS51292:39=[C]>) and (<Feature:PS51292:26=[C]> and <Feature:PS51292:28=[C]> and <Feature:PS51292:52=[C]> and <Feature:PS51292:55=[C]>)
ZN_FING	from	to	/note="RING-CH-type #"
else case (<Feature:PS51292:9=[CH]> and <Feature:PS51292:12=[CH]> and <Feature:PS51292:36=[CH]> and <Feature:PS51292:39=[CH]>) and (<Feature:PS51292:26=[CH]> and <Feature:PS51292:28=[CH]> and <Feature:PS51292:52=[CH]> and <Feature:PS51292:55=[CH]>)
ZN_FING	from	to	/note="RING-CH-type #; atypical"
else
ZN_FING	from	to	/note="RING-CH-type #; degenerate"
end case
BINDING	9	9	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1"		[CH]	1
BINDING	12	12	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1"		[CH]	1
BINDING	26	26	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2"		[CH]	2
BINDING	28	28	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2"		[CH]	2
BINDING	36	36	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1"		[CH]	1
BINDING	39	39	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#1"		[CH]	1
BINDING	52	52	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2"		[CH]	2
BINDING	55	55	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_label="#2"		[CH]	2