PROSITE entry PS51350
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General information about the entry
| Entry name [info] | PTS_HPR_DOM |
| Accession [info] | PS51350 |
| Entry type [info] | MATRIX |
| Date [info] |
01-DEC-2007 CREATED;
13-FEB-2019 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00318 |
| Associated ProRule [info] | PRU00681 |
Name and characterization of the entry
| Description [info] | PTS HPR domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=88; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=83; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6502614; R2=0.0069629; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=5964.5078125; R2=4.0539331; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=841; H_SCORE=9374; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=553; H_SCORE=8206; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-63; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='M'; M= -2,-154, -60, 4,-141, -44, -87, -36, -50,-101, 120, -33, -19, -10, -57, -44, -7, -11, 40, -85; /M: SY='V'; M= 16, -56, -73, 6, -32,-154, 13, 18, -18, 20, 2,-108, 19, 22, -49, -77, -53, 31,-152, 17; /M: SY='E'; M= -50, -31, -82, 53,-151, -91, -50, -25, 13,-149, -37, -79,-118, 39, 18, 52, 28, -39,-156, 5; /M: SY='R'; M= 10, -28, -91, -42, 15, -15, -66, -42, 46, -29,-138, -28,-151, 38, 61, -79, -25, -5,-152, -81; /M: SY='E'; M= -54, -21, 14, 60,-127,-150, -25, -25, 7, -54,-143, -38,-121, 37, 11, 6, 53, -41,-162,-146; /M: SY='V'; M= -2, -54,-161, -88, 57,-159, -95, 38,-106, 3, -48,-155,-158,-155,-155,-106, -9, 63, 53, -57; /M: SY='T'; M= -65,-150, -43, 21, -34, -59, 21, 7, -5, -32, -71, -44, -38, -20, -17, -54, 75, 32,-162,-142; /M: SY='I'; M=-104, 11,-164,-160, 7,-166,-161, 83,-157, 9, -52,-157, -64,-156,-159, -86,-137, 59,-155, -95; /M: SY='T'; M= 13, -11, -23, -48, -99, -17, -53, 26, 21, -51, -49, -9, -2, -8, 19, -26, 33, 23, -78, -67; /I: I=-26; MI=0; MD=-65; IM=0; DM=-65; /M: SY='N'; M= 12, -16, 10,-137,-147, -96, 24, -67, -92, -19,-143, 101, -75, -43,-123, 10, -74, -96, 33, 3; /M: SY='P'; M= -6,-158, -7, 37, -99, -53, -34, -99, 44, -83,-147, -12, 72, -23, 26, 6, -55, -89,-159,-150; /M: SY='H'; M= -27,-151, -48, -56, -75, -31, 67, -17, -31, 28, -73, 44,-151, -19, 14, 3, 25, 3, -54,-138; /M: SY='G'; M= -98,-156, -92, -91,-161, 105,-149,-169, -80,-165,-155, -13,-148,-146,-155, -68,-146,-163,-154, -62; /M: SY='L'; M= -46,-150, -77,-156, -46,-164,-150, 39,-154, 82, 28,-159,-160,-149, -46,-154,-141, -32, -70,-133; /M: SY='H'; M= -76,-159, -93,-107, -95, -83, 151,-163,-137,-117,-134, -85, -55, -12,-132, -37, -59,-162,-179,-119; /M: SY='A'; M= 95,-142,-147,-141,-151, -62,-149, -67,-142, -84,-139,-141, -84,-140, -93, -23, 14, -7,-156, -81; /M: SY='R'; M= -84,-162,-142,-131,-106,-156, 13,-161, -73,-154,-143,-101,-154, -45, 120,-102, -60,-155,-155, -66; /M: SY='P'; M= 39,-160,-147, -99,-159, -79, -80, -50,-142, -95,-145, -88, 116, -40,-152, -49, -99, -31,-158, -71; /M: SY='A'; M= 95, -89,-145,-139,-154, -33,-147,-103,-140, -83,-142,-138,-146,-137, -45, 39, -58,-134,-156,-150; /M: SY='A'; M= 76,-144, -48, -72,-153, -32, -56, -82, -32,-146, -13, -42,-145, -9,-143, 35, 45, -43, -16,-147; /M: SY='K'; M= -7, -70, -74, -19,-142,-153, 13, -4, 50, 24, 38, -69, -32, 24, 29, -61, -16, -4,-155, -62; /M: SY='F'; M= -47, -88,-166,-159, 70,-164,-153, 42,-157, 63, -67,-160,-161,-156,-156,-154, -92, -15, 43,-122; /M: SY='V'; M= 34,-146,-152, -44, -42,-124,-154, -55, -55, -82, -54, -59,-153, -95, -23, -14, 5, 87,-162, -67; /M: SY='Q'; M= -14,-156, -27, 41, -93, -27, 4,-117, 49, -98,-144, 19,-145, 74, 20, -27, -13, -71,-157, -68; /M: SY='T'; M= 38, -12,-143, 28, -24, -96, -86, -52, 7, 36, 5,-142,-148, -49,-118, -72, 42, 13,-156,-141; /M: SY='A'; M= 88, 21,-151,-144, -38,-137,-151, -41,-145, -24, -37,-145, -74,-143,-149, -40, -42, 32,-157,-146; /M: SY='S'; M= 10,-151, -25, -13,-156, -2, -47,-110, 52,-119,-146, 29,-145, 21, 24, 52, -11, -76,-158,-146; /M: SY='K'; M= -25,-155, -32, 26,-156, 23, -76, -91, 56, -73,-145, -12, -23, 30, 46, 4, 1,-151,-156, -67; /M: SY='F'; M= -40, -75,-158, -48, 111,-158, 8, -42,-151, -32,-130,-151,-161, -45, -63, -42, -58,-134, 2, 56; /I: I=-26; MI=0; MD=-65; IM=0; DM=-65; /M: SY='D'; M= -1, -97, 53, 24,-159, -10, -23,-100, 31,-107, -60, 30, 11, 37, -17, 23, -25,-124,-161,-148; /M: SY='S'; M= 54, 62, -60,-111,-152, -33, -68,-119, -30, -71,-101,-132,-147,-135,-143, 85, -78, -37,-161,-148; /I: I=-29; MI=0; MD=-74; IM=0; DM=-74; /M: SY='D'; M= -43,-156, 66, 58,-158,-103, 13,-106, 0,-111, -87, -5, -10, 25, 9, 7, 14, -86,-163, -64; /M: SY='I'; M= -30, -81,-162,-158, -40,-164,-161, 83,-155, -3, -30,-155,-155,-154,-157, -89, -62, 69,-157,-137; /I: I=-30; MI=0; MD=-77; IM=0; DM=-77; /M: SY='T'; M= -97, -49, -71, 8, 8,-128, 24, -39, -12, -15, -60, -14,-128, 36, 28, 0, 69, -47, 46, -17; /I: I=-29; MI=0; MD=-74; IM=0; DM=-74; /M: SY='I'; M= -84,-150,-164,-158, -25,-165,-157, 61,-156, 53, -4,-159,-158,-153,-156,-151,-137, 60, 30,-133; /I: I=-10; MI=0; MD=-27; IM=0; DM=-27; /M: SY='R'; M= -9,-155, -49, 46, -53, -49, 27, 9, -69, -67,-140,-138,-149, -35, 47, -6, 43, 6,-163,-145; D=-10; /I: I=-10; MI=0; MD=-27; IM=0; DM=-27; /M: SY='K'; M= -6, -13,-138,-136, -12,-147, 35,-151, 59,-120, -11, 54,-153, -32, 28, 1, -89, -49,-151, 45; D=-10; /I: I=-10; MI=0; MD=-27; IM=0; DM=-27; /M: SY='D'; M= -40,-159, 72, -4,-165, 41,-137,-164, -8,-106,-155, 64,-150, 20, -18, -92,-140,-161,-169,-154; D=-10; /I: I=-10; MI=0; MD=-27; IM=0; DM=-27; /M: SY='G'; M=-135,-158, 44, 7,-165, 83,-144,-168,-143,-166,-157, 16, -43, -22,-150, -3, -59,-163,-162,-157; D=-10; /I: I=-10; MI=0; MD=-27; IM=0; DM=-27; /M: SY='K'; M= -32, -77, -64, 21,-153, -96, -21, -75, 67, -63, -24, -3, -48, 28, 63, -73, -32, -18, -46, -36; /I: I=-29; MI=0; MD=-74; IM=0; DM=-74; /M: SY='S'; M= -17, -4, -66, 25,-127, -59, -22, -75, 23, -42, -84, -48, 14, 27, 9, 42, 33, 1, 20,-144; /I: I=-28; MI=0; MD=-71; IM=0; DM=-71; /M: SY='V'; M= 62, -84, -84,-149,-103, -31,-156, 7,-149, -87, -45,-149, -71,-148,-152, -70, -34, 78,-160, -76; /I: I=-32; MI=0; MD=-81; IM=0; DM=-81; /M: SY='N'; M= -57,-151, 69, -2,-158, -45,-131,-155, -89, -67,-151, 91, -21, -64,-140, 41, -47, -78,-171,-150; /M: SY='A'; M= 83, -35,-149,-145,-149, 38,-150, -34,-146, 4, -54,-142, -17,-143,-150,-108, -58, -48,-155,-149; /M: SY='K'; M= -13,-154, 4, -60,-157, -34,-138, -64, 95,-123, -75, -48, -89, -50, 24, -37, 14,-149,-155,-146; /I: I=-27; MI=0; MD=-68; IM=0; DM=-68; /M: SY='S'; M=-123,-145, -10,-134,-155, -75,-137,-154, -40,-157,-150, 5, -75, -41, -48, 110,-117,-147,-162,-146; /M: SY='I'; M= -15,-151,-160,-155, -89,-159,-154, 74,-153, 43, 35,-153, -33, -64,-154, -3, -79, 29,-155,-137; /M: SY='M'; M= -66,-149,-158,-153, 6,-106,-142, 20,-149, 38, 116, 5,-154,-144,-149, -49, -36, 11,-152,-131; /M: SY='G'; M= 34, -61, -44, -11,-157, 62,-141,-156, 30,-108, 0, 3, -82, -12, -7, 29, -95,-149,-156,-150; /M: SY='L'; M=-141,-149,-164,-157,-125,-165,-155, 58,-156, 64, 5,-159,-159,-152,-156,-152,-137, 57,-155,-135; /M: SY='M'; M= -8,-148,-159,-150, -36,-156,-141, 14,-148, 51, 116,-151,-153, 12,-147,-147, -65, -10,-151,-132; /M: SY='M'; M= 23,-146,-144,-100,-145, 20,-140, -49,-103, -31, 90,-108,-145, 23, -30, 52, 40, -99,-156,-141; /M: SY='L'; M= -31,-147,-161,-101, -58,-109,-147, -79,-155, 93, -6,-159,-160,-148,-153,-114, -33, -38,-150,-133; /M: SY='G'; M= 44,-151, 19, -17, -45, 79,-144,-158, -26,-156, -87, -32,-146, 4, -45, -40,-139, -88,-155,-150; /M: SY='A'; M= 64, -28,-152,-147, -60,-122,-152, 28,-147, 19, -66, -93,-151,-144,-150, 0, -1, 46,-156,-141; /M: SY='K'; M= 17, -39, -67, -27,-151, 31, 1, -76, 39, -36, -99, -63, -12, 23, 37, 24, 1, -51,-154, -33; /M: SY='Q'; M= -24, 26,-136, 6, -46, -29, 38, -45, 56, -52, -20, -27, 6, 75, 3, -36, -44, -81,-152, -3; /M: SY='G'; M=-116,-155, -28,-103,-160, 100, -15,-166, -64,-135,-152, 31, -18, -27,-150,-128,-144,-162, -31,-108; /M: SY='D'; M= 16, 0, 68, 15,-155, -47, 30, -50, -9,-150, -58, -43,-144, -1, -32, 20, 51, -64,-165,-116; /M: SY='E'; M= -51, -68, -6, 55, -61,-110, 1, -48, 17, -21, 0, -25, -76, 17, 27, 10, 40, -12,-158, -52; /M: SY='I'; M= -56, 46,-163,-158, -40,-164,-159, 71,-156, 34, -38,-156,-158,-154,-157,-149, -83, 63,-157,-137; /M: SY='T'; M= -67,-104, -18, 48, -56,-117, 4, -42, -4, -23, -70, -54,-144, 46, 28, -48, 67, -5,-159, -66; /M: SY='I'; M=-141, -78,-164,-159, 26,-166,-157, 72,-156, 44, -71,-158,-158,-155,-157,-151,-137, 58,-151,-131; /M: SY='S'; M= -39, -11, -83, 22, -88, -90, 15, 24, -21, -13, -32, -48,-147, -8, 28, 46, 36, 4, -84, -36; /I: I=-21; MD=-53; /M: SY='A'; M= 82, 34,-151,-146, -83, -37,-153, 22,-146, -87,-136,-143,-149,-144,-151, -29, 16, 10,-159,-148; D=-21; /I: I=-21; MD=-53; /M: SY='E'; M= -44,-156, 44, 66, -79,-148, -47, -25, -13,-120, -82, -15, -60, 18, -12, 33, 20, -58, -36, -90; D=-21; /I: I=-21; MI=0; MD=-53; IM=0; DM=-53; /M: SY='G'; M=-102,-158,-113, -70,-163, 103,-152,-168,-150,-119,-155,-101, -42,-148,-158, -57, -78, -70,-156,-159; D=-21; /I: I=-21; DM=-53; /M: SY='P'; M= 7, -79, 35, 53,-156, -55, -38, -36, -17, -67, -35, -23, 65, -30, -43, 29, -14, -64, -70,-149; /M: SY='D'; M= -81,-159, 109, 8,-115, -22, -46, -46, -27,-123,-154, -17,-146, 37, -64, -70, -92,-157,-171,-102; /M: SY='A'; M= 79, -12, -25, 77,-158, -74,-141,-151,-132,-150, -56, -59, -81,-127,-109, -57,-135,-102,-158,-151; /M: SY='E'; M= 19,-155, 37, 65,-158, -83, -19, -68, 14, -64,-144, -19, -37, 57, -29, -17, -47, -21,-160,-147; /M: SY='E'; M= 35,-154, 28, 67,-154,-127, -77, -54, -8, -14,-141, -54, -60, 55, 0, -60, -47, -44, -42,-146; /M: SY='A'; M= 99, -73,-104,-141, -54, -66,-150, -55,-143, -51, -66,-143,-147,-140,-148,-123, -38, -7,-155,-148; /M: SY='L'; M= -18, 13,-161,-154, -29,-160, -11, 30,-109, 66, 51, -72,-159,-123, -75, -89,-139, 33,-154, -67; /M: SY='D'; M= 25,-155, 63, 50, -24,-114, -20, -71, -3, -79, -19, -2, -42, 50, -16, -35, -40, -75,-160,-144; /M: SY='A'; M= 75, -39, -73, 26,-125, -26, 9, -88, 8, -93,-141, -48,-146, -21, 2, -28, -10, -15,-157, -55; /M: SY='L'; M=-144,-150,-164,-158, 0,-166,-153, 55,-157, 74, -24,-160,-160,-153,-156,-154,-140, 27,-151,-132; /M: SY='A'; M= 36, 22, -77, 29,-116, -5,-145, 1, 14, -6, -42,-132,-147, 9, -33, 8, 12, 12,-158,-145; /M: SY='E'; M= 42, -48, 38, 49,-119, -54, -18, -80, 9, -72,-145, 12, -25, 34, -4, -24, -16, -82,-160,-101; /M: SY='L'; M= 18, -94,-157, -30, 29,-156,-147, -12,-151, 68, 5,-117,-157,-147, -91,-145, 3, -7, 15, 1; /I: I=-27; MI=0; MD=-68; IM=0; DM=-68; /M: SY='I'; M= -14,-150,-164,-158, 43,-162, -90, 63,-156, 45, 33,-157,-158,-153,-156,-150,-139, 36,-148,-129; /M: SY='E'; M= 35,-152, 7, 59,-158, -72, -86,-117, 3,-134,-146, 44,-144, 30, -1, 13, -10, -43,-161,-112; /M: SY='D'; M= 19, -58, 41, 25,-158, -48, -29,-155, 4, -91,-148, 38,-147, 32, -11, 37, -8, -69,-163, -43; /I: I=-22; MD=-57; /M: SY='G'; M= -41,-160, 23, 14, -97, 48, 22,-162, 31, -53,-151, 19, -45, -43, 30, -60, -55,-101,-162, -42; D=-22; /I: I=-22; MI=0; MD=-57; IM=0; DM=-57; /M: SY='F'; M= -12, -31,-165, -71, 93,-140, 3, -27,-105, 42, -87,-133, -50, -60,-157, -84,-148, -81,-139, -54; /M: SY='G'; M= -20,-162, 55, -43,-164, 66, -35, -21,-114,-111,-156, -32, -12, -70, -65, -31, -22, -81,-167, -58; /M: SY='E'; M= -7,-167, -16, 96, -92,-161, -12,-118, -11, -78,-157,-104,-147,-127, -76,-119,-148, -49,-169,-158; /M: SY='E'; M= -3, -28, 16, 36,-170, 10, -51, -87, -44, -44, -62, -58, -9, -32, -69, -11, -31, -19,-177,-165; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
| Total number of hits | 83 in 82 different sequences |
| Number of true positive hits | 83 in 82 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Archaea, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 2 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | HPr |
| Version [info] | 6 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
82 sequences
CRH_BACSU (O06976), CRH_HALH5 (Q9K708), DHAM_ECOLI (P37349), DHAM_KLEM8 (A0A0H3H456), DHAM_PANAM (D4GL26), DHAM_PROSM (P0DN88), PTFAH_ECO57 (P69812), PTFAH_ECOLI (P69811), PTFAH_HAEIN (P44715), PTFAH_SALTI (Q8Z591), PTFAH_SALTY (P17127), PTFAH_VIBCH (Q9KM70), PTFAX_RHOCA (P23388), PTFAX_XANCP (P45597), PTFX1_ECOLI (P77439), PTFX2_ECOLI (P32670), PTFX_ECO57 (Q8XBQ8), PTFX_ECOL6 (Q8FFD8), PTFX_SHIFL (Q83QP3), PTHP_BACSU (P08877), PTHP_BACTI (Q9F166), PTHP_BORBU (O51507), PTHP_BUCAI (Q9WXI5), PTHP_BUCAP (Q8KA49), PTHP_BUCBP (Q89B03), PTHP_CHLMU (Q9PK56), PTHP_CHLPN (Q9Z9E4), PTHP_CHLTR (O84341), PTHP_CUPNH (P23537), PTHP_ECO57 (P0AA06), PTHP_ECOL6 (P0AA05), PTHP_ECOLI (P0AA04), PTHP_ENTFA (P07515), PTHP_GEOSE (P42013), PTHP_HAEIN (P43921), PTHP_HALH5 (Q9K8D2), PTHP_HALVD (D4GYE3), PTHP_KLEPN (P16481), PTHP_LACCA (Q9KJV3), PTHP_LACLA (Q9CJ83), PTHP_LACLC (Q9ZAD9), PTHP_LATSK (O07125), PTHP_LISIN (P0A439), PTHP_LISMO (P0A438), PTHP_LYSSH (Q84F84), PTHP_MYCCT (P45611), PTHP_MYCGE (P47287), PTHP_MYCPN (P75061), PTHP_NEIMA (P65876), PTHP_NEIMB (P65877), PTHP_PRIMG (O69250), PTHP_PSEAE (Q9HVV2), PTHP_PSEPU (Q9Z426), PTHP_SALTI (P0AA08), PTHP_SALTY (P0AA07), PTHP_SHIFL (P0AA09), PTHP_STAAC (Q5HH02), PTHP_STAAM (P0A0E1), PTHP_STAAN (P99143), PTHP_STAAR (Q6GI02), PTHP_STAAS (Q6GAD1), PTHP_STAAU (P0A0E3), PTHP_STAAW (P0A0E2), PTHP_STACA (P23534), PTHP_STAXY (Q9EYQ9), PTHP_STRCO (O50515), PTHP_STREI (Q9WXK8), PTHP_STRMU (P45596), PTHP_STRSA (P24365), PTHP_STRSL (P24366), PTHP_TREPA (O83598), PTHP_VIBCH (Q9KTD6), PTHP_XYLFA (Q9PDH6), PTHP_XYLFT (Q87DQ0), PTSO_ECO57 (P0A9N2), PTSO_ECOL6 (P0A9N1), PTSO_ECOLI (P0A9N0), PTSO_KLEOX (P51185), PTSO_PROMH (Q9ZA86), PTSO_SHEVD (Q9S0K8), PTSO_SHIFL (P0A9N3), PTSO_VIBCH (Q9KP46)» more
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| PDB [Detailed view] |
56 PDB
1CM2; 1CM3; 1FU0; 1GGR; 1HDN; 1J6T; 1JEM; 1K1C; 1KA5; 1KKL; 1KKM; 1MO1; 1MU4; 1OPD; 1PCH; 1PFH; 1POH; 1PTF; 1QFR; 1QR5; 1RZR; 1SPH; 1TXE; 1VRC; 1Y4Y; 1Y50; 1Y51; 1ZVV; 2AK7; 2FEP; 2HID; 2HPR; 2JEL; 2LRK; 2LRL; 2NZU; 2NZV; 2OEN; 2RLZ; 2XDF; 3CCD; 3EZA; 3EZB; 3EZE; 3OQM; 3OQN; 3OQO; 4XWJ; 5T17; 5T1N; 5T1O; 5YA0; 5YA1; 5YA2; 6KCR; 7X7H » more |