ProRule PRU00681
General rule information
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Accession | PRU00681 |
Dates | 14-MAY-2008 (Created)
13-JAN-2023 (Last updated, Version 6) |
Data class | Domain; |
Predictors |
PROSITE; PS51350; PTS_HPR_DOM |
Name | PTS HPR domain |
Function | The histidine-containing phosphocarrier protein (HPr) is a central component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), which transfers metabolic carbohydrates across the cell membrane in many bacterial species. |
Scope(s) |
Bacteria Archaea |
Example(s) | P08877 (PTHP_BACSU); |
Propagated annotation
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Keywords
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Kinase | |
case <Feature:PS51350:46=S> and <OC:Bacillota> | |
Phosphoprotein | |
end case | |
Phosphotransferase system | |
Transferase |
Gene Ontology
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GO:0009401; Biological process:phosphoenolpyruvate-dependent sugar phosphotransferase system |
GO:0016740; Molecular function:transferase activity |
GO:0016301; Molecular function:kinase activity |
Cross-references
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Features
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From: PS51350 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | /note="HPr #" | |||||||||
case <AnyFeature:PS51094:61=H> or <AnyFeature:PS51096:9=H> | ||||||||||||
ACT_SITE | 15 | 15 | /note="Pros-phosphohistidine intermediate; for HPr activity" | H | ||||||||
else | ||||||||||||
ACT_SITE | 15 | 15 | /note="Pros-phosphohistidine intermediate" | H | ||||||||
end case | ||||||||||||
case <Feature:PS51350:46=S> and <OC:Bacillota> | ||||||||||||
MOD_RES | 46 | 46 | /note="Phosphoserine; by HPrK/P" | |||||||||
end case |
Additional information
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Size range | 80-95 amino acids |
Related rules |
None |
Fusion | None |
Repeats | 1-2 |
Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Archaea [1] Bacteria [81] All [ 82 ]
- Retrieve set of proteins with 3D structure for this domain