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ProRule PRU00681


General rule information [?]

PURL https://purl.expasy.org/prosite/rule/PRU00681
Accession PRU00681
Dates 14-MAY-2008 (Created)
13-JAN-2023 (Last updated, Version 6)
Data class Domain;
Predictors PROSITE; PS51350; PTS_HPR_DOM
Name PTS HPR domain
Function The histidine-containing phosphocarrier protein (HPr) is a central component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), which transfers metabolic carbohydrates across the cell membrane in many bacterial species.
Scope(s) Bacteria
Archaea
Example(s) P08877 (PTHP_BACSU);

Propagated annotation [?]

Keywords [?]

Kinase
case <Feature:PS51350:46=S> and <OC:Bacillota>
Phosphoprotein
end case
Phosphotransferase system
Transferase

Gene Ontology [?]

GO:0009401; Biological process:phosphoenolpyruvate-dependent sugar phosphotransferase system
GO:0016740; Molecular function:transferase activity
GO:0016301; Molecular function:kinase activity

Cross-references [?]

PROSITE PS00369; PTS_HPR_HIS; 1;
PROSITE PS00589; PTS_HPR_SER; 1;

Features [?]

From: PS51350
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="HPr #"
case <AnyFeature:PS51094:61=H> or <AnyFeature:PS51096:9=H>
ACT_SITE 15 15 /note="Pros-phosphohistidine intermediate; for HPr activity" H
else
ACT_SITE 15 15 /note="Pros-phosphohistidine intermediate" H
end case
case <Feature:PS51350:46=S> and <OC:Bacillota>
MOD_RES 46 46 /note="Phosphoserine; by HPrK/P"
end case

Additional information [?]

Size range 80-95 amino acids
Related rules None
Fusion None
Repeats 1-2
Topology Undefined

Copyright

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UniProtKB rule member sequences [?]