General rule information
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Accession |
PRU00681 |
Dates |
14-MAY-2008 (Created) 13-JAN-2023 (Last updated, Version 6) |
Predictors |
PROSITE; PS51350; PTS_HPR_DOM
|
Function |
The histidine-containing phosphocarrier protein (HPr) is a central component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), which transfers metabolic carbohydrates across the cell membrane in many bacterial species. |
Propagated annotation
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case <Feature:PS51350:15=H>
end case
case <Feature:PS51350:46=S>
end case
GO:0009401; Biological process: phosphoenolpyruvate-dependent sugar phosphotransferase system.
GO:0016740; Molecular function: transferase activity.
GO:0016301; Molecular function: kinase activity.
case <Feature:PS51350:46=S> and <OC:Bacillota>
end case
From: PS51350 |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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DOMAIN
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from
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to
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HPr #
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case <AnyFeature:PS51094:61=H> or <AnyFeature:PS51096:9=H>
ACT_SITE
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15
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15
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Pros-phosphohistidine intermediate; for HPr activity
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H
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else
ACT_SITE
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15
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15
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Pros-phosphohistidine intermediate
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H
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end case
case <Feature:PS51350:46=S> and <OC:Bacillota>
MOD_RES
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46
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46
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Phosphoserine; by HPrK/P
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end case
Additional information
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Size range |
80-95 amino acids |
Related rules |
None |
Repeats |
1-2 |
Topology |
Undefined |
Example |
P08877 (PTHP_BACSU) |
Scope |
Bacteria
Archaea |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
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