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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS51370


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PURL: https://purl.expasy.org/prosite/signature/PS51370

Direct ScanProsite submission
General information about the entry

Entry name [info] R
Accession [info] PS51370
Entry type [info] MATRIX
Date [info] 01-FEB-2008 CREATED;
13-FEB-2019 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51370
Associated ProRule [info] PRU00702

Name and characterization of the entry

Description [info] R domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=18;
/DISJOINT: DEFINITION=PROTECT; N1=2; N2=17;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3189075; R2=0.0066435; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=831.7242432; R2=0.5957580; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=931; H_SCORE=1386; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=630; H_SCORE=1207; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-34; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-105; BD=-105;
/M: SY='K';  M=-35,-60,-46,-34,-50,-49,-54,-55, 82,-54,-39,-34,-22,-42, 38, 21, -3,-45,-55,-51;
/M: SY='E';  M=  0,-47, 20, 76,-59,-12,-48,-36,-31,-10, 36,-47,-46,-41,-51,-47,-49,  5,-53,-53;
/M: SY='S';  M=-39,-53,-45,-23,-11,-22,-48,-18,-42, -3,-45,  7,-44,-48,-49, 86,-15,-47,-60,-20;
/M: SY='R';  M=-48,-57,-51,-49,-48,-12,-51,-60,-23,-56,-45,-54,-50,-27,104,-46,-59,-52,  1,-39;
/M: SY='A';  M= 64, 31, -2, 43,-54,-18,-53,-20,-42,-45,-43,-45,-48,-40,-50,-35, -8, 14,-60,-60;
/M: SY='K';  M=-44,-59,-44,-32,-50,-49,-53,-54, 90,-51,-21, 11,-41, 24, 31,-41,-49,-54,-53,-50;
/M: SY='A';  M= 91,-56,-40,-37,-52,-45,-55,-45,-44,-50,-39,-43,-49,-37,-49,-36, 10,-23,-70,-67;
/M: SY='R';  M=-48,-56,-51,-49,-48,-55,-50,-60,-34,-56,-45,-54,-51,-26,107,-46,-59,-51,-45,-39;
/M: SY='A';  M= 79,-53,-40, 38,-55, -9,-52,-48,-25,-51,-41,-44,-40, 11,-42,-39,-33,-35,-61,-64;
/M: SY='R';  M=-48,-58,-49,-44,-49,-53,-50,-59, 35,-56,-43,-52, 12,-29, 96,-45,-56,-52,-47,-42;
/M: SY='A';  M= 89,-61,-44,-49,-56, -5,-59,-49,-48,-55,-43,-47,-52,-41,-53,-40,-42,-41,-71,-72;
/M: SY='R';  M=-52,-59,-53, -3,-53,-54,-54,-64,  8,-59,-42,-56,-52,-31, 97,-47,-61,-56,-49,-44;
/M: SY='E';  M=-31,-50,-41, 89,-75,-34,-53,-70,-20,-58,-57,-57,-49,-44,-59,-55,-63,-70,-58,-66;
/M: SY='R';  M=-58,-67,-61,-60,-58,-57,-61,-70,-44,-66,-55,-64,-60,-36, 96,-55,-30,-61,-56,-49;
/I:         I=-12; MI=0; MD=-25; IM=0; DM=-25;
/M: SY='T';  M= -5,-69,-57,-43,-67,-62,-67,-57,-59,-56,-58,-50,-21,-57,-69, 10, 88,-51,-83,-65;
/M: SY='K';  M=-56,-34,-59,-46,-62,-56,-62,-65, 53,-64, 32,  3,-60,-46, 45,  4,-35,-64,-66,-61;
/M: SY='E';  M=-12,-55,-18, 76,-75,-65,-58,-62,-13,-61,-59,  6,-54,-49,-62,-57,-43,-70,-65,-42;
/M: SY='K';  M=-29,-74,-59,-41,-63,-63,-65,-67, 75,-65, 25,-57,-56,-53, 29,-55,-57,-65,-66,-62;
/I:         E1=0; IE=-105; DE=-105;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 11 in 11 different sequences
Number of true positive hits 11 in 11 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 84.62 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] R
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
11 sequences

CYCLD_ANTCI (Q9SBV9), CYCLD_ANTLN (Q9SBV6), CYCLD_ANTMA (O49250), 
DICH_ANTMA  (Q9SNW8), TB1_MAIZE   (Q93WI2), TB1_ORYSJ   (Q8LN68), 
TCP12_ARATH (A0AQW4), TCP18_ARATH (A1YKT1), TCP1_ARATH  (Q9FYG7), 
TCP24_ARATH (Q9C758), TCP2_ARATH  (Q93V43)
» more

UniProtKB/Swiss-Prot
False negative sequences
2 sequences

AUXI1_ARATH (Q9SU08), AUXI2_ARATH (Q0WQ57)