PROSITE entry PS51388
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General information about the entry
| Entry name [info] | GED |
| Accession [info] | PS51388 |
| Entry type [info] | MATRIX |
| Date [info] |
01-JUN-2008 CREATED;
10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51388 |
| Associated ProRule [info] | PRU00720 |
Name and characterization of the entry
| Description [info] | GED domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=92; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=87; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.4376628; R2=0.0077610; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=14085.8056641; R2=4.3883495; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=910; H_SCORE=18079; N_SCORE=9.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=524; H_SCORE=16385; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-37; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='A'; M= 36, 30,-114, 11, -49,-118, -35, 26, -6, -2, 18, -33, -47, -2,-112, -11, 10, 30,-126, -43; /M: SY='E'; M= -9,-124, 19, 53, -3, -56, -35, -25, -13, 12, 16, -29, -27, 42, 12, 7, -63, -69,-124, -47; /M: SY='E'; M= -6,-123, 32, 58, -32, -69, -31, -28, 11, -2, 14, 8, -53, 18, -26, -52, 10, -29, 0, -51; /M: SY='I'; M= -7,-119,-123, -58,-102,-126,-120, 66, -14, 19, 51, -44,-121,-114, -52, -34, 29, 29,-125, -33; /M: SY='H'; M= 9, -36,-115, -74, -52, -74, 58, 30, 13, 2, 23, -49, -33, 26, 43, -13, -59, -28,-122, 10; /M: SY='D'; M= 27, -40, 65, 19, -29,-111,-106, -28, -48, -23, -25, 41,-116, 12, -11, 6, 0, -70,-130, -37; /M: SY='C'; M= -70, 64, -3, -36,-106, -48, 46, -5, -10, 38, -14, -18, -41, -26, 35, -7, -30, -47,-124, 16; /M: SY='M'; M= -15, -12,-127,-122, -42, -72,-119, 24,-120, 49, 70, -23, 11,-117,-122,-114, -5, 43,-125,-106; /M: SY='E'; M= -1, -13, 36, 49,-121,-117, -32, -48, 11, -14,-111, -12,-115, 19, 40, 7, 1, -34,-128, -34; /M: SY='S'; M= 57,-115, -42, -60,-120, 4, -29, -1,-108, -53, -23, -33, -40, -35, -23, 63, 3, -35,-128,-116; /M: SY='Y'; M=-119,-129,-118,-121, 11,-126, -26, -64,-113,-102, -99, -24, -54,-110, -47, -63,-113, -60, -80, 134; /M: SY='Y'; M= -61,-124,-125,-124, 68, -45, -29, -97,-118, 12, 40, -57,-129,-116,-116, -41,-112, -26, 53, 103; /M: SY='K'; M= -9,-122, 20, 38,-122, -40,-104, -22, 56, -42, -8, 49,-114, 31, -36, -27, 6, -68,-127, -35; /M: SY='I'; M= -17, -30, -60, -41,-103, -76, -26, 73,-117, -21, 2, -43,-121,-117, -32, -52, 21, 59,-128,-108; /M: SY='V'; M= 64, -9,-119, -40, -45, -58,-121, -15,-114, -51, -14,-114,-119, -44,-118, 22, -57, 66,-128,-113; /M: SY='M'; M= 6, -34,-114, -51, -22, -35,-106, -16, 10, 27, 57, -3,-120, 17, 56, 10,-105, -35,-120, -16; /M: SY='K'; M= -72,-124, 30, -35, -59, -11,-105,-119, 87, -50, 5, -6, -50, -5, 25, -54, -32, -33,-122, -18; /M: SY='R'; M= -23, -34,-105, -15,-117,-116, -44, -21, 4, -79,-108, 37, -43, 8, 81, -7, 40, -9,-126, -19; /M: SY='F'; M=-113,-119,-132,-126, 87,-131,-118, 42,-123, 31, 36,-124,-128, -43,-122, -69, -54, 34,-106, -28; /M: SY='I'; M= 26, -30,-118, -32,-108,-119, -32, 57, -35, -34, -42, -56,-119, 0, 21, 2, 9, 42, 38,-108; /I: I=-19; MI=0; MD=-47; IM=0; DM=-47; /M: SY='D'; M= -5,-121, 94, -55,-124, -48, -98, -33,-101,-125,-119, 85,-117, -14,-109, -57, -54, -70,-138, -10; /M: SY='V'; M= -23, -34,-111, -33, -38, -36, -31, 8,-109, -20, 23, 25,-118, 31,-112, 42, 29, 51,-126, -21; /M: SY='V'; M= 28, 43,-123,-120,-105, -76,-125, 57, -44, -26, -94, -42,-122,-117, -52, -23, 0, 66, -25,-110; /M: SY='P'; M= -14, 29, -59,-108, -8, -43, -20, -17, -40, -74, 7, -15, 97, -50, -20, -14, -4, 20,-126,-115; /M: SY='Q'; M=-110,-123, -48, -62, -57,-121,-106, -39, 70, 49, 35,-106,-118, 77, -91, -47,-107,-105,-119,-106; /M: SY='A'; M= 61, -11,-118,-114, 17, -36, 18, -2, -53, -37,-100,-110,-118,-112, -58, -1, 25, 43,-121, 0; /M: SY='I'; M= -50, -18,-129,-126, -99,-133,-129, 87,-122, 10, -86,-122,-123,-121, -53,-115, 6, 57,-126,-106; /M: SY='M'; M= -55, -44, -18, 68, -55, -25, -3, -35, -37, -33, 77, 28,-114, 25, 1, -36, -62, 6,-126, -45; /M: SY='H'; M= -55, -1, -27,-107, -10,-116, 86, -32, -99, -33, -37, 41,-121, -50, 51, 19, -7, -35,-116, 63; /M: SY='C'; M= -45, 81, -59, 23, 55, -44, 75, -30, -23, -11, 20, -56,-121, -20, 7, -29, -6,-109,-120, -36; /M: SY='M'; M=-112,-118, -68,-121, -10,-130,-113, 17,-121, 78, 78,-125,-127, -14,-119, -57,-109, -14,-118, -31; /M: SY='V'; M= -73, -32,-129,-123, 13,-131,-123, 47, -31, 54, -30, -50,-127, -39,-120,-118,-105, 63,-121,-101; /I: I=-21; MI=0; MD=-53; IM=0; DM=-53; /M: SY='N'; M= -69,-123, 34, -19, -72, -71, -8,-121, 22, -31,-112, 58, -5, 35, 49, 30, -49, -70,-126, -2; D=-21; /I: I=-21; DM=-53; /M: SY='H'; M= -30, -30, 12, 23, -34, 14, 51,-120, 40, -21, -37, 21, 21, 12, -1, -15, 7,-118,-126, -52; /M: SY='L'; M= 7, 16, -23,-115, 21,-119,-116, -1,-117, 47, -40, -55, 35,-115,-119, 19, 8, 21,-120, -20; /M: SY='P'; M= -18, 33, -53, 29, -29, -6, 25, -64, 31, -23, -7, -22, 33, 25, 17, 1, -12, -49,-122, 5; /M: SY='D'; M= -23,-122, 48, 34,-120, -30, 6,-120, 19, -24,-112, 20,-114, 9, 33, 24, 18, -78,-127, -8; /M: SY='Q'; M= -60,-122, 9, 16, -9, -40, -48, 44, -26, -3,-100, 32, -8, 56, -66, 5, -5, 6,-125,-108; /M: SY='F'; M= -45,-118,-131,-124, 70,-129,-115, 6, -67, 65, 58,-125, -32,-120,-120, -69,-109, -10,-109, -27; /M: SY='Q'; M=-104, -31, 2, 11, -46,-112, 32, -58, -53, -1,-107, 3, 13, 70, 11, 52, 14,-113,-125, -24; /M: SY='P'; M= -33,-125, 3, -3, -23, -33, -34,-116, 9, -19,-110, 23, 74, 27, 30, 17, -13, -39,-126,-114; /M: SY='E'; M= 1,-121, 13, 63,-117, -39, 4, -25, -14, -36,-107, -21,-112, 30, -1, -7, 24, 17,-127, -17; /M: SY='L'; M= -19,-118, -52, -47, -14, -74,-115, 19, -45, 67, 61,-121,-124, -25, -32,-116, -18, 4, 22, -42; /M: SY='V'; M= -11,-119, 2, -8, 12, -34, -2, 26, -54, 4, -7,-115,-122, -21, -58,-110, -29, 67,-119, 26; /M: SY='S'; M= 20, 33, -16, 7, -62, -4, 4, -13, -22, -44, -20, 31, -25, 29, 8, 34, 3, -27,-127, -46; /M: SY='Q'; M= 0, -32, 6, 37,-123, -1, 11,-117, 24, -26, -45, 46,-115, 49, 29, -11,-104, -21,-128,-113; /M: SY='M'; M= -38,-118,-128, -26, 7,-129,-113, 15, -66, 74, 79,-125,-126,-114,-119,-120,-109, -13,-116, -19; /M: SY='Y'; M= -16,-120, 23,-106, -23, 17, -11, -51,-107, -20, 13, -10, -30, 37, -51, 30, 25, -18,-112, 68; /M: SY='D'; M= -14,-123, 73, -7,-121, 2, 23, -14, 24, -45,-112, 9,-115, 13, -13, 3, 1, -38,-130, -16; /M: SY='N'; M= 17,-121, 29, 50, -31, -35,-102,-121, 16, -77,-114, 53, -2, 15, -11, 15, -22, -68,-125, -8; /I: I=-15; MD=-39; /M: SY='E'; M= -26,-131, 49, 68,-132, -7, 12,-131, -65, -27,-122, -8, -30, 2, -51, -11, -16,-127,-138,-123; D=-15; /I: I=-15; MI=0; MD=-39; IM=0; DM=-39; /M: SY='Q'; M= 3,-134, -8, -22,-131, -27, -37, -33, 3, -4, -34, -7,-129, 69, 4, -48, -36, -35,-137,-123; D=-15; /I: I=-15; DM=-39; /M: SY='L'; M= -14, 16, -62,-121, -9,-128,-119, 41,-121, 50, 16,-123, -19, -9,-122, -39, -66, 40,-120, 13; D=-15; /I: I=-15; DM=-39; /M: SY='E'; M= -35,-125, 47, 52, -10, -52, -9, -64, -9, -32, -8, 19, -8, 22, 32, -16, -25, -28,-128, -51; D=-15; /I: I=-15; DM=-39; /M: SY='R'; M= 14,-123, 16, 35, -32, -37, -31,-121, 6, -52, -36, 8,-116, 40, 52, 27, -58, -72, 18, -45; D=-15; /I: I=-15; DM=-39; /M: SY='L'; M=-113, -13, -38,-124, 9,-132,-118, 55,-123, 70, 53, -44,-127,-119,-123,-121,-108, -7, -4, -99; /M: SY='A'; M= 70,-113,-124,-116, -28, -54,-115, -17,-117, 55, 63,-118,-121,-112,-118,-104,-105, -22,-120,-106; /M: SY='A'; M= 38, -33, -30, 19,-122, 20,-107,-119, 14, -76, 0, 20,-114, 34, 5, 35, -10, -57, 16, -56; /M: SY='E'; M=-108,-129, -8, 115,-129,-123,-101,-129, -90,-123,-120,-104, -10, -83,-100,-105,-108, -58,-127, -34; /M: SY='D'; M= -73, -12, 76, -58,-126, -68, 2,-124,-101,-125, -16, 44, 36, -46, -6, 62, -2,-120,-137,-116; /M: SY='P'; M= -14, -35, 5, 33, -56,-112, -36, -41, 12, -74,-114, 11, 90, 7, -59, 27, -62, -46,-128,-119; /M: SY='E'; M= 9,-123, 43, 50,-118, -11, 37, -43, -20, -61,-111, -6, -28, 22, 7, 9, -13, -25,-125, 13; /M: SY='I'; M= -15,-118, -27, -46, -42,-124,-120, 59, -63, -2, -93, -31, -39, 1, -14, -16, 30, 57,-127,-108; /M: SY='A'; M= 48,-118,-112, -37,-116, -47, 20, -26, 25, -13, -4,-106, -39, 33, 34, -16, 12, 18,-125,-111; /I: I=-30; MD=-77; /M: SY='Q'; M= 35, -37, 14, 38,-124, -50, -9, -40, 7, -57, 11, -26,-116, 48, 26, -26, -14, -15,-129,-115; D=-30; /I: I=-30; MI=-77; IM=-77; DM=-77; /M: SY='K'; M= -42,-126, -42, 55,-123, -51, -32, -5, 57, -44, -37, -25,-113, 53, 57, -50,-107,-115,-123,-112; /M: SY='R'; M=-114,-130, -44, -99,-122,-124, 21, -51, -42,-120,-110,-103,-122, -29, 119,-108,-113, -50,-125,-109; /M: SY='Q'; M= 4,-122, 36, 43,-122, -50, -37, -23, 43, -15,-109, 24,-113, 47, -16, -45, 12, -46,-128,-113; /M: SY='E'; M= -2, -18, 13, 43, 6, -70, 14, -67, 30,-116, -5, -8,-114, 39, 37, -2, 3, -81, 6, -2; /M: SY='C'; M= 15, 72, -49,-119, -98,-124, -37, -16,-120, 71, -2,-120,-127, -42,-121, -51, -8, 0,-124, -35; /M: SY='Q'; M= 1, 5, -55, 12,-118, -8,-107, -11, 49, -10,-105, -14,-115, 62, 18, -4, -5, -20,-123, -38; /M: SY='E'; M= -1,-123, 8, 56,-123, -29, -1, -31, 44, -72,-111, 9,-112, 41, 31, -16, -23, -36,-126, -48; /M: SY='R'; M= -27,-123, -17, 31,-119,-117,-103, -63, 49, -16, 45, 6,-115, 41, 54, -6, -11, -28,-125,-111; /M: SY='L'; M= -38,-120,-118, -14,-100,-126, -19, 33, 24, 59, -34, -53,-123, 8, -3, -33,-106, 23,-121, -16; /M: SY='E'; M= 3,-123, 14, 58, -60, -69, -34, -71, 52, -54, -32, -15,-111, 43, 17, -11, 7,-116, -8,-113; /M: SY='R'; M= 37, 1, -39, -38, -61, -73, -25, -5, 26, 10, 12, -27, -39, -35, 43, -12, -33, 24,-125,-110; /M: SY='L'; M=-115,-118, -38,-122, -8,-132,-114, -57,-124, 91, -21,-128, -17,-118,-122,-123,-110, -36,-115, 11; /M: SY='E'; M= -38,-124, -12, 58,-124, -75, -10, -40, 52, -71,-111, -23,-112, 49, 32, 16, -9, -23,-126,-113; /M: SY='E'; M= 12,-123, -11, 65,-123, -29, -24, -66, 41, -25,-111, -13, -58, 45, 13, -14, -33, -58, -9,-114; /M: SY='A'; M= 83, -8,-114,-112, -27, 42,-117, -61,-112, -70,-110,-105,-115,-109,-117, 21, -24, -37,-123,-116; /M: SY='Q'; M= -23,-121,-112, -20, -26,-119, -34, -43, 20, 39, 56, -20, -46, 58, 3, 11, -31, -46,-116, 26; /M: SY='Q'; M= -15,-122, 14, 40, -9, -36, -18, -54, 31, -48,-110, 7,-114, 56, 30, 4, 12, -32,-124, -45; /M: SY='I'; M= 12, 8, -38, 13,-111,-120,-115, 55, 17, -30, -43, -58, -54, 15, 9, -17, 15, 24, -1,-110; /M: SY='L'; M= -60, 67, -64,-125, 22,-131,-122, 48,-125, 67, -85,-125, -53,-122,-125,-120,-108, 11, -7,-101; /M: SY='K'; M= 15, -39, -2, 19,-121, -15, 3,-120, 39, -60, -5, 31, -14, 8, 39, 23, -19, -71,-125, -23; /M: SY='E'; M= 14,-121, 17, 49, -70, -18, -7, -59, -18, -76, -10, -7,-112, 45, 34, 36, 3, -75,-127,-113; /M: SY='L'; M= 0, 27, -9,-119, 33,-126, 34, 23, -67, 35, -9, -51, -4,-118,-121, -45, -63, 35,-121, -5; /M: SY='R'; M= -24,-125, -7, -14,-120, -15,-110, -22, -12, -56, 39, 4, 24, 36, 46, 14, -23, 11,-129, -47; /M: SY='M'; M= 21, -36, 35, 0, -64, 7, 4, -35, -12, -58, 45, -3, 0, -22, 5, -11, 0, -31, -3,-115; /M: SY='Q'; M= 9,-125, -8, -24, -11, -17, -2, -24, 2, 20,-105, -24, -18, 34, 24, 1, -15, -33,-126, -26; /M: SY='H'; M= 13, -10, -30, -4, -61, -10, 31, -74, 2, -10, -43, -23, -53, 24, 16, 8, 10, -15,-130, -12; /M: SY='F'; M= 4,-126, -18, -28, 21, -2, -37, -41, -39, 5, -31, 4, -7, -15,-121, -2, 15, 9,-128, -25; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
| Total number of hits | 83 in 83 different sequences |
| Number of true positive hits | 83 in 83 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | GED |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
83 sequences
DMP34_HUMAN (Q6PK57), DMP46_HUMAN (Q6ZS02), DNM1L_BOVIN (Q2KIA5), DNM1L_CAEEL (Q8WQC9), DNM1L_DANRE (Q7SXN5), DNM1L_HUMAN (O00429), DNM1L_MOUSE (Q8K1M6), DNM1L_RAT (O35303), DNM1_SCHPO (Q09748), DNM1_YEAST (P54861), DRP1A_ARATH (P42697), DRP1B_ARATH (Q84XF3), DRP1C_ARATH (Q8LF21), DRP1D_ARATH (Q8S3C9), DRP1E_ARATH (Q9FNX5), DRP2A_ARATH (Q9SE83), DRP2B_ARATH (Q9LQ55), DRP3A_ARATH (Q8S944), DRP3B_ARATH (Q8LFT2), DRP4C_ARATH (Q9ZP55), DYN1_BOVIN (Q08DF4), DYN1_CAEEL (P39055), DYN1_HUMAN (Q05193), DYN1_MOUSE (P39053), DYN1_RAT(P21575), DYN2_BOVIN (A6H7I5), DYN2_HUMAN (P50570), DYN2_MOUSE (P39054), DYN2_RAT(P39052), DYN3_HUMAN (Q9UQ16), DYN3_MOUSE (Q8BZ98), DYN3_RAT(Q08877), DYNA_DICDI (Q94464), DYNB_DICDI (Q9U1M9), DYN_DROME (P27619), MGM1_CHATD (G0SGC7), MGM1_YEAST (P32266), MSP1_SCHPO (P87320), MX1B_MOUSE (P09922), MX1_BOVIN (P79135), MX1_CANLF (Q9N0Y3), MX1_EUMJU (Q4ADG8), MX1_HORSE (Q28379), MX1_HUMAN (P20591), MX1_ICTPU (Q7T2P0), MX1_MACMU (A1E2I4), MX1_MOUSE (Q3UD61), MX1_ONCMY (Q91192), MX1_OTABY (Q4ADG7), MX1_PHOVI (Q4ADG6), MX1_PIG (P27594), MX1_PONAB (Q5R5G3), MX1_RAT (P18588), MX1_SHEEP (P33237), MX2_BOVIN (Q9BDI7), MX2_BUBBU (A0MWD1), MX2_CANLF (Q9N0Y2), MX2_HUMAN (P20592), MX2_ICTPU (Q4U4N4), MX2_MACMU (A1E2I5), MX2_MOUSE (Q9WVP9), MX2_ONCMY (Q91196), MX2_PIG (A7VK00), MX2_RAT (P18589), MX2_SHEEP (Q5I2P5), MX3_ONCMY (Q91197), MX3_RAT (P18590), MXA_DANRE (Q8JH68), MXB_DANRE (Q800G8), MXC_DANRE (Q6DKF0), MXE_DANRE (Q800G5), MX_ANAPL(P33238), MX_CHICK(Q90597), MX_CTEID(Q6TKS7), MX_DICLA(Q2KTC2), MX_EPICO(Q6PW23), MX_LARCR(Q000A9), MX_SINCH(Q6TN15), MX_SOLSE(Q5U752), SDL5A_SOYBN (Q39828), SDLCA_SOYBN (Q39821), VPS1_SCHPO (Q9URZ5), VPS1_YEAST (P21576)» more
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| PDB [Detailed view] |
33 PDB
3LJB; 3SNH; 3SZR; 3ZVR; 3ZYS; 4BEJ; 4UUD; 4UUK; 4WHJ; 4X0R; 5A3F; 5GTM; 5UOT; 5WP9; 6DLU; 6DLV; 6JSJ; 6QL4; 6RZT; 6RZU; 6RZV; 6RZW; 6S9A; 7AX3; 8SXZ; 8SZ4; 8SZ7; 8SZ8; 8T0K; 8T0R; 8T1H; 8TYM; 8TYN » more |