ProRule PRU00720
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00720 |
| Accession | PRU00720 |
| Dates | 31-JUL-2008 (Created)
21-NOV-2019 (Last updated, Version 3) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51388; GED |
Name | GED domain |
| Function | Dynamin superfamily members are large GTPases, conserved through evolution mainly described as mechanochemical enzymes involved in membrane scission events. All members display a common architecture: a large GTPase domain followed by a 'middle domain' of ill-defined function and a downstream coiled-coil GTPase effector domain (GED) that functions in higher order assembly and as a GTPase activating protein (GAP) for dynamin's GTPase activity. |
| Scope(s) |
Eukaryota |
| Example(s) | Q05193 (DYN1_HUMAN); |
Propagated annotation
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Features
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| From: PS51388 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="GED #" | |||||||||
Additional information
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| Size range | 70-100 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [83] All [ 83 ]
- Retrieve set of proteins with 3D structure for this domain