ProRule PRU00720

General rule information [?]

Accession PRU00720
Dates 31-JUL-2008 (Created)
21-NOV-2019 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51388; GED
Name GED domain
Function Dynamin superfamily members are large GTPases, conserved through evolution mainly described as mechanochemical enzymes involved in membrane scission events. All members display a common architecture: a large GTPase domain followed by a 'middle domain' of ill-defined function and a downstream coiled-coil GTPase effector domain (GED) that functions in higher order assembly and as a GTPase activating protein (GAP) for dynamin's GTPase activity.
Scope(s) Eukaryota
Example(s) Q05193 (DYN1_HUMAN);

Propagated annotation [?]

Features [?]

From: PS51388
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="GED #"

Additional information [?]

Size range 70-100 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

View rule in raw text format (no links)

UniProtKB rule member sequences [?]