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annotation rule: PRU00720 |
Accession | PRU00720 |
Dates | 31-JUL-2008 (Created) 21-NOV-2019 (Last updated, Version 3) |
Data class | Domain |
Predictors | PROSITE; PS51388; GED |
Name | GED domain |
Function | Dynamin superfamily members are large GTPases, conserved through evolution mainly described as mechanochemical enzymes involved in membrane scission events. All members display a common architecture: a large GTPase domain followed by a 'middle domain' of ill-defined function and a downstream coiled-coil GTPase effector domain (GED) that functions in higher order assembly and as a GTPase activating protein (GAP) for dynamin's GTPase activity. |
From: PS51388 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DOMAIN | from | to | GED # |
Size range | 70-100 amino acids |
Related rules | None |
Repeats | 1 |
Topology | Undefined |
Example | Q05193 (DYN1_HUMAN) |
Scope | Eukaryota |
Eukaryota | [81] |