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| annotation rule: PRU00720 |
General rule information
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| Accession | PRU00720 |
| Dates | 31-JUL-2008 (Created) 16-DEC-2016 (Last updated, Version 2) |
| Data class | Domain |
| Predictors | PROSITE; PS51388; GED |
| Name | GED domain |
| Function | Dynamin superfamily members are large GTPases, conserved through evolution mainly described as mechanochemical enzymes involved in membrane scission events. All members display a common architecture: a large GTPase domain followed by a 'middle domain' of ill-defined function and a downstream coiled-coil GTPase effector domain (GED) that functions in higher order assembly and as a GTPase activating protein (GAP) for dynamin's GTPase activity. |
Propagated annotation
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Features
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| From: PS51388 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | GED # | |||||||||
Additional information
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| Size range | 70-100 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | Q05193 (DYN1_HUMAN) |
| Scope | Eukaryota |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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UniProtKB/Swiss-Prot sets
Eukaryota [80]
- Retrieve set of proteins with 3D structure for this domain