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annotation rule: PRU00720

General rule information [?]

Accession PRU00720
Dates 31-JUL-2008 (Created)
16-DEC-2016 (Last updated, Version 2)
Data class Domain
Predictors PROSITE; PS51388; GED
Name GED domain
Function Dynamin superfamily members are large GTPases, conserved through evolution mainly described as mechanochemical enzymes involved in membrane scission events. All members display a common architecture: a large GTPase domain followed by a 'middle domain' of ill-defined function and a downstream coiled-coil GTPase effector domain (GED) that functions in higher order assembly and as a GTPase activating protein (GAP) for dynamin's GTPase activity.

Propagated annotation [?]


Features [?]

From: PS51388
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       GED #        

Additional information [?]

Size range 70-100 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q05193 (DYN1_HUMAN)
Scope
Eukaryota

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.



UniProtKB rule member sequences [?]