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PROSITE entry PS51409


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General information about the entry

Entry name [info] ARGINASE_2
Accession [info] PS51409
Entry type [info] MATRIX
Date [info] 01-NOV-2008 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00135
Associated ProRule [info] PRU00742

Name and characterization of the entry

Description [info] Arginase family profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=292;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=287;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3469489; R2=0.0058415; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=1448; N_SCORE=10.8; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=711; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-19; D=-100; I=-100; B1=-350; E1=-350; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-105; BD=-105;
/M: SY='R';  M= -42, -56,  16,   5,   1, -50,  12, -45,  13, -37,  17,  -7,  10,  -9,  55, -22, -22, -20, -54, -36;
/M: SY='L';  M=   7, -48,  -7, -30,   2, -53, -25,  22, -28,  44, -18, -47, -54, -19, -20, -18, -36,  -3, -51, -33;
/I:         I=-22; MD=-23;
/M: SY='P';  M= -28, -75, -50,  -8, -75, -58, -28, -67, -37, -73, -34,  10,  76, -51, -60, -29, -33, -68, -75, -70; D=-22;
/I:         I=-22; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='M';  M= -26, -73, -24, -13, -62, -53, -59, -25,  -8, -34,  -2, -30, -15, -26, -38, -12, -33, -31, -73, -11; D=-22;
/I:         I=-22; DM=-23;
/M: SY='P';  M= -38, -21,   8, -31,  -7, -57, -47, -57, -10, -35,  -2,   5,  28,  -7,  -4, -10, -23, -57, -63,  -7; D=-22;
/I:         I=-22; DM=-23;
/M: SY='D';  M= -21, -61,  20,   2, -22,  -6, -44, -21, -19, -28, -24, -40,  -1,   7, -31,   9, -41, -26, -56,  12; D=-22;
/I:         I=-22; DM=-23;
/M: SY='Y';  M=  -4, -54,   7,   3, -30, -30, -39, -43, -12, -39, -18,  -1, -12, -37, -31,  13,  10,  -8, -50,  36; D=-22;
/I:         I=-22; DM=-23;
/M: SY='E';  M=  11, -52,   1,  41, -39,  -5, -37, -49,  14, -37,  -3,   7, -42,   3, -14,   4, -12, -35,  25, -44; D=-22;
/I:         I=-22; DM=-23;
/M: SY='D';  M= -18, -52,  31,  20, -53,  24,  18, -49,  24, -40,  -4,   0,  22,   5, -10,  -3, -33, -26, -56, -43; D=-22;
/I:         I=-22; DM=-23;
/M: SY='K';  M=  19,   5,  -2,  -1,  -8, -13,  24, -28,  29, -23, -16,   6,  -1,   9,   4,   1, -17, -16, -45,  13;
/M: SY='D';  M=   2, -48,  56,  -1, -52,  31,   6, -50,  10, -50, -43,  -3,  -9,   1,  -6,   3,  10, -33, -56, -28;
/M: SY='V';  M=   7,  14, -52, -47,  16, -35, -48,  36, -45,   5,  -7, -46,  -8, -45, -48, -11, -20,  50,  31,   4;
/M: SY='A';  M=  46,  -1, -28, -30, -42,  30, -44, -18, -28, -33,  -7, -33, -42, -21, -42,   7,   6,  34, -53, -41;
/M: SY='I';  M= -26, -44, -57, -52,  34, -58, -50,  57, -50,  40,  -9, -51, -52, -48, -51, -45, -21,  33, -42, -22;
/M: SY='I';  M= -28, -17, -56, -51,  14, -57, -50,  51, -49,  35,   8, -49, -51, -47, -50, -42,  -3,  46,  -3, -26;
/M: SY='G';  M=   0, -48, -37, -46, -53,  86, -42, -57, -41, -43, -27, -12, -12, -38, -48,  -5, -24, -51, -48, -49;
/M: SY='F';  M=  16, -15, -52, -33,  57, -49, -43,  19, -45, -12,  21, -47, -51, -46, -46, -37, -30,  49, -34,  27;
/M: SY='P';  M=  26,  -3, -38, -17, -55,  -7, -42, -44, -25, -52, -41, -19, 100, -36, -44, -24, -30, -33, -52, -52;
/M: SY='C';  M= -37,  75, -50, -48,  67, -48,  -7, -16, -45,   4,  20, -41, -54, -45, -45,  14, -32,  -8, -29,  44;
/M: SY='D';  M= -25, -49,  92,   1, -57, -12, -28, -55, -28, -55, -51,   1, -39,  -4, -35,  31, -17, -51, -68, -43;
/M: SY='E';  M=  12, -45, -18,  37, -29,  20,  -5, -20,  20,  -7,  -5, -12, -38,  -6, -29,  15,  10, -35,  -1, -38;
/M: SY='G';  M=  17, -45, -36, -43, -52,  79, -42, -54, -39, -52, -44,  -9, -40, -37, -46,  -5,  21, -45, -49, -48;
/M: SY='Q';  M=  -4, -42, -38, -19, -36, -44, -39,   7, -32, -18, -24, -19, -42,  51, -35,   9,  36,  49, -53, -14;
/I:         I=-29; MI=0; MD=-30; IM=0; DM=-30;
/M: SY='S';  M= -21,  -4, -22, -27, -47,   4,  26, -14,  25, -30, -36,  -2,  27,  22, -18,  49,  11, -38, -53, -38;
/I:         I=-32; MD=-33;
/M: SY='G';  M= -43, -62, -52, -60,  23,  54,  -4, -38, -54, -52, -49, -13, -59, -52, -57, -20, -50, -56,  11,  39; D=-32;
/I:         I=-32; MI=-33; IM=-33; DM=-33;
/M: SY='R';  M= -27, -54, -18, -23, -48, -47,   9, -53,  35, -35, -36, -18, -45,  -4,  91, -32, -25, -47, -49, -35;
/M: SY='P';  M=  -7, -50, -22,  -7, -45, -18, -38,  -6,   2, -17, -32, -34,  67,   7,  25,   4,   6,   7, -52, -42;
/M: SY='G';  M= -22, -49, -37, -49, -55,  92, -44, -60, -43, -58, -47, -23, -41, -40, -50, -15, -40, -39, -47, -50;
/M: SY='A';  M=  63,  33, -42, -37, -42, -31, -45, -24, -38, -33, -30, -35, -17, -36, -42,  10,  14,  32, -54, -42;
/M: SY='R';  M=  23, -48,  26,  27, -48, -39, -29, -48,  21, -38, -38,   1, -41,  -9,  60, -11, -31, -32, -50, -15;
/I:         I=-27; MD=-28;
/M: SY='F';  M=  -2, -47,   9,  12,  61, -18,  38, -31,   4,   5,  29, -12, -46, -13, -34, -35, -35, -33, -36,  -1; D=-27;
/I:         I=-27; MI=0; MD=-28; IM=0; DM=-28;
/M: SY='G';  M=  39, -45, -39, -44, -54,  80, -44, -55, -41, -53, -44, -27, -41, -38, -47, -14, -36, -46, -48, -49; D=-27;
/I:         I=-27; DM=-28;
/M: SY='P';  M= -32, -64, -40, -29, -57, -29, -43, -47, -36, -57, -43, -46, 116, -39, -48, -36, -32, -52,  12, -54;
/M: SY='D';  M=  12,  -7,  45,  13, -48, -24, -31, -27,  10, -28,  12,  10,  -1,  18,  -3,  20,   2, -38, -56, -40;
/M: SY='A';  M=  57, -39, -39, -21, -17,   0,  15, -21, -34, -15,   5, -33, -42, -19, -13,  10,   0,  -7, -44,  16;
/M: SY='I';  M= -37, -47, -58, -54, -10, -61, -51,  74, -51,  38,  12, -51, -50, -47, -52, -47, -32,  23, -45, -15;
/M: SY='R';  M= -39, -54, -37, -17, -43, -51, -29,  -3,  23, -12, -31, -31, -47, -16,  92, -35, -37, -30, -48, -35;
/M: SY='E';  M=  -8, -50, -23,  47, -44, -21,  -4, -37,  28, -45, -37, -26, -37,  41,  33,   4,   8, -43, -45,  13;
/M: SY='A';  M=  68, -10, -36,   1, -46,  -6, -13, -23, -23, -33,  -6, -23, -40,   0, -37,   5, -18,  -5, -50, -42;
/M: SY='S';  M= -26, -43, -40, -42,   0,  37, -18, -17, -39,  34,  10, -18, -45, -34, -32,  46, -15, -29, -45, -12;
/M: SY='A';  M=  42, -42,  -7, -36, -18,  -8, -15, -13, -15,  29, -23, -37, -45, -15,   2, -10, -14,   0,  31, -14;
/M: SY='N';  M= -16,  -5, -30, -32, -39,  11,   4,   4,   2,   1,   3,  56,  -6,  17,  27, -28, -20, -22, -51, -15;
/M: SY='L';  M= -20, -44, -12,  16,  12, -31, -36,  -1, -22,  48,  31, -40, -28,   1, -39,  -6, -14,  -5, -44,  -9;
/M: SY='P';  M=  30, -47,   0,  18, -50, -11, -14, -40,  -1, -44, -17, -12,  49,  22,  13,   3, -16,  -6, -52, -42;
/I:         I=-23; MD=-24;
/M: SY='W';  M=  11, -19, -48, -23, -14, -24, -48,   3, -42,  20, -28, -15,  12, -41, -28,  -4,  10, -13,  88, -30; D=-23;
/I:         I=-23; MD=-24;
/M: SY='Y';  M= -54, -68, -45,  22, -21, -64,  13, -32,  -8, -35, -47, -17, -28, -22,  -6, -31, -35, -25, -49,  48; D=-23;
/I:         I=-23; MI=0; MD=-24; IM=0; DM=-24;
/M: SY='H';  M= -37, -60,  13,  41, -30, -22,  51, -44, -22, -55, -48,  17, -17,   6,  15, -11, -41, -57, -63, -23; D=-23;
/I:         I=-23; DM=-24;
/M: SY='L';  M= -45, -53, -54, -20,  17, -45, -22, -24, -28,  44,  20, -53,  20, -11, -48, -28, -19, -19,  31, -18; D=-23;
/I:         I=-23; DM=-24;
/M: SY='G';  M= -27, -56,  37,  -8, -61,  54,  -1, -62, -38, -61, -52, -27,  32, -14, -27,   9, -28, -58, -60, -51; D=-23;
/I:         I=-23; DM=-24;
/M: SY='W';  M= -19,  17, -39,  -9, -14, -46,  63, -35, -11,   4, -17, -19, -47, -20,  10, -24,  14, -26,  90,  49;
/I:         I=-17; MI=0; MD=-18; IM=0; DM=-18;
/M: SY='D';  M= -25, -67,  69, -13, -72, -51,  33, -72, -43, -70, -63,  28, -57, -12, -49, -42, -46, -69, -87, -55; D=-17;
/I:         I=-17; DM=-18;
/M: SY='P';  M= -38,   6, -60, -40, -47, -16, -59,  -9, -41,  18, -22, -28,  38, -39, -60, -42, -46,  14, -67, -53; D=-17;
/I:         I=-17; MI=0; MD=-18; IM=0; DM=-18;
/M: SY='L';  M= -12, -63, -35,   2, -52, -65, -56,  -2, -18,   9, -39, -55, -62, -21,   5, -20, -29,  -5, -68, -53; D=-17;
/I:         I=-17; DM=-18;
/M: SY='P';  M=   9, -48,  21,   6, -26, -27,  11, -28,  29, -29, -12,   8,  40,   0,  17,   2,  -5, -30, -52, -38;
/M: SY='V';  M=  -8,  30, -54, -49,   4, -55, -46,  42, -32,  30,   5, -49, -52, -45, -31, -41, -30,  45, -44,  14;
/M: SY='Y';  M=   5,  10, -40, -11,   7, -37,   1,  16,  -6, -21, -25,  -9, -46,  -9,   2, -12,   5,  29, -36,  51;
/M: SY='D';  M= -41, -54, 103,   0, -35, -38, -11, -57, -28, -55, -54, -10, -15, -27, -27, -29, -22, -54, -71, -27;
/M: SY='C';  M=  26,  59, -13, -41,  -6, -18, -21, -22, -24,  34,  14, -27, -34, -38, -31, -21, -32,   2, -42,  28;
/M: SY='G';  M= -23, -50, -24, -26, -55,  89, -42, -61,  -8, -50, -47, -23, -21, -37, -44, -23, -40, -56, -47, -50;
/M: SY='D';  M= -27, -49,  91, -11, -54, -35, -26, -18, -12, -51, -48,  45, -40, -17, -34, -20,   3, -46, -70, -42;
/M: SY='I';  M= -21,  12, -53, -33, -15, -44, -13,  56, -46,  18,  19, -47,   4, -24, -48, -42, -31,  41,  -5,  -5;
/M: SY='P';  M=   0, -46,  16,   9, -13, -33,  12,  -5, -14, -17, -30,  -6,  36,  -1, -10,  -8,  20,  21,  -6, -17;
/I:         I=-32; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='C';  M= -14,  73, -50, -30,  26, -24,  19,  15, -45,   9,  16, -43, -16, -45, -47, -38, -12,  35,  -6,   4;
/I:         I=-12; MI=0; MD=-13; IM=0; DM=-13;
/M: SY='P';  M= -12, -51,  27,  18, -53, -39,   6, -21, -11, -51, -43,  48,  56, -29, -27,  -9,  14, -35, -62, -46; D=-12;
/I:         I=-12; MI=0; MD=-13; IM=0; DM=-13;
/M: SY='P';  M=  -4, -48,  21, -14,   3,   4,  10, -35, -35,  -1,  -7,  -1,  61, -34, -41,  10,  -5, -20, -46,  10;
/M: SY='G';  M= -17, -49,  35,   1,  -1,  39, -13, -33,  10, -16, -37,  11, -14, -28,  24, -28,  -8, -43, -45,  10;
/M: SY='D';  M=   8, -46,  59,  14, -32, -27,  -4, -31, -14, -14, -22,  32, -40,  11, -14,  18, -10, -40, -55,  -8;
/M: SY='L';  M= -17,  -4, -21, -42,  -4, -39, -19,  15, -42,  42,  -2,   0,  22, -23, -26, -30, -30,  37, -50, -31;
/M: SY='E';  M= -10, -48,  -8,  58, -47,  13, -32, -20, -14, -19, -15,  -9, -37,  26,  -2,  21, -20,  -5, -52, -41;
/M: SY='E';  M=  21, -47,  28,  32, -45, -13, -31, -12,  14, -10, -34,  14, -18,  16,   5,   2, -29, -31, -51, -17;
/M: SY='A';  M=  48,  20, -41, -38,  -9,   8, -11, -14, -19, -27,  -8, -32, -42, -35, -40,  21,  14,  14,  20, -24;
/M: SY='Q';  M= -33,  31, -16, -25, -10, -43,  41,  -4, -20, -10,   7,  12, -14,  70, -29, -20,  27,  -4, -50, -11;
/M: SY='Q';  M=   0, -51,  38,  37, -51, -21,  19, -35,   7, -26, -38,   4,  -2,  44,  25,  -7, -31, -45, -54, -38;
/M: SY='Q';  M=  28, -22, -29,  20, -45, -38,   4, -11,  14, -14, -13,   2, -28,  48,  20,  -5,   4, -34, -49, -24;
/M: SY='L';  M= -16,  -1, -57, -51,   6, -57, -45,  47, -49,  52,  26, -51, -52, -45, -49, -45, -33,  21, -44,  -8;
/M: SY='A';  M=  40, -43, -15,  25, -26,   0,  13, -31, -26, -41,  -9, -17, -39,  21,   8,  28,  -7, -28, -48,  -6;
/M: SY='E';  M= -10, -49,  27,  44, -53,   5, -15, -41,  26, -42, -41,  19, -37,  31,  17,   0,  -6, -46, -53, -41;
/I:         I=-17; MI=0; MD=-18; IM=0; DM=-18;
/M: SY='A';  M=  32, -42, -27, -15, -40, -13,  30,  -8,  15, -18,   0, -20, -41,  11,   4,  -2,  14,  19, -51, -19;
/M: SY='V';  M=  21, -40, -32, -45, -29, -47, -49,  31, -44,  -9,   9, -43, -47, -43, -46, -14,   1,  65, -53,  -7;
/M: SY='H';  M=  30, -21,  -5,  -6, -29, -19,  38, -43,   7, -29, -34,  -7, -40,  20,  19,  24,  18, -37, -49,   5;
/M: SY='K';  M=  12, -48,  20,  32, -34,   0,  -4, -35,  34, -33, -12,   1, -38,  30,  20, -10, -13, -42, -51, -39;
/M: SY='V';  M=  -9,  26, -48, -22, -26, -37,  27,  31, -37,  34,   9, -43, -49, -26, -44,  -9, -23,  40, -53, -31;
/I:         I=-25; MI=0; MD=-26; IM=0; DM=-26;
/M: SY='L';  M=  11, -43, -48, -40,   0, -49,  -1,  21,  -9,  50,  -2, -43, -49,  -1,  -2, -20, -24,   4, -45, -28;
/I:         I=-28; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='K';  M=  16, -24,   8,  29, -51, -13, -15, -49,  37, -36, -39, -12,  -5,  30,  16,  24, -20, -43, -51, -40;
/M: SY='N';  M=  28,  -4,  29,  19, -34, -28, -12, -43,   1, -21, -37,  30, -40,  20,  12,  18, -16, -26, -54, -39;
/M: SY='G';  M= -15,   9,  15, -36, -53,  73,  19, -57, -21, -55, -45,  35, -42,  -6, -21, -23, -35, -43, -53, -45;
/I:         I=-28; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='H';  M=   8,   6, -25, -22, -39, -23,  45, -40,  35, -12,   8, -23,   3, -26,  32, -17, -27, -20,  26,   7; D=-28;
/I:         I=-28; DM=-29;
/M: SY='F';  M= -12, -21, -45, -36,  50, -39, -19,  15,   7,  17,  -6, -38, -31,  21,  33, -22, -21,  -4, -38, -20;
/M: SY='P';  M=  -8,  14, -44, -36, -16, -44, -45,   2, -39, -18,   7, -43,  90, -41, -47, -22,   6,  19, -52, -42;
/M: SY='I';  M= -36, -17, -57, -51,   2, -60, -50,  56, -50,  47,  -8, -52, -52, -25, -50, -46, -32,  38, -47, -28;
/M: SY='V';  M=  -3,  -1, -45, -43,   8,  -9, -45,  13, -41,  -2,  22, -21, -44, -41, -44,   2,  41,  47, -52, -31;
/M: SY='L';  M= -40, -43, -58, -51,  19, -59, -43,  31, -51,  68,  20, -54, -55, -45, -49, -49, -35,   1, -42, -23;
/M: SY='G';  M= -22, -50, -37, -49, -56,  94, -44, -64, -43, -59, -48, -23, -41, -40, -50, -22, -41, -57, -47, -51;
/M: SY='G';  M= -22, -50, -37, -49, -56,  94, -44, -64, -43, -59, -48, -23, -41, -40, -50, -22, -41, -57, -47, -51;
/M: SY='D';  M= -33, -53,  82,  26, -59,  50, -31, -60, -30, -57, -52, -15, -39, -28, -39, -26, -34, -56, -61, -46;
/M: SY='H';  M= -84,-107, -51, -52, -83, -86, 266,-117, -61, -84, -55,   6, -36, -12, -51, -62, -79,-116,-149, -23;
/M: SY='S';  M=  -5, -42,  17,  44,  -3, -21, -31, -44, -27, -30, -40, -23, -36, -21, -33,  60,  18, -38, -50, -11;
/M: SY='I';  M= -27, -46, -55, -52, -23, -58, -53,  76, -48,  19,  14, -46, -47, -46, -51, -41,  13,  27, -49, -30;
/M: SY='A';  M=  62, -36, -36, -34, -47,   6, -41, -38, -34, -41, -36, -28, -17, -32, -40,  31,  38, -17, -52, -43;
/M: SY='W';  M= -25, -50, -53, -49,  39, -52, -35,  30, -44,   8,   2, -48, -52, -42, -44, -28,  -9,   1,  90,  70;
/M: SY='G';  M=  27, -49, -39, -39, -54,  67, -43, -51, -39, -53, -19, -31,  63, -38, -47, -15, -34, -46, -49, -50;
/M: SY='T';  M=   6, -39, -34, -34, -37, -37,  33,   4, -34,   1, -26,   3, -40,  -2, -38,  35,  54,   8, -56, -34;
/M: SY='Y';  M= -36, -45, -54, -51,  33, -21, -16,  28, -47,  31, -14, -49, -53, -46, -47, -43, -33,  42,  37,  44;
/M: SY='R';  M=  18, -18, -34, -17, -44, -29, -31, -31,  18,   2, -31,   2, -26,  30,  52,  26, -28, -30, -49, -37;
/M: SY='G';  M=  51, -42, -38, -40, -52,  69, -42, -50, -39, -50, -41, -12, -21, -36, -45,  -8, -20, -40, -48, -48;
/M: SY='H';  M= -16, -43, -48, -45,  18, -52,  48,  33, -44,  25,  24, -41, -48, -41, -44, -29,  12,  37, -46,   1;
/M: SY='A';  M=  51,  -5,  -9, -31, -38, -18,   3, -35,  -6,   6, -29,  -3, -20,   3,  13,   6, -28, -22, -10,   0;
/I:         I=-12; MD=-13;
/M: SY='R';  M=   9, -49,  23,  14, -51, -24,  15, -49,  32, -32, -38,  -2, -41,  23,  46,   9, -30, -36, -53, -38; D=-12;
/I:         I=-12; MD=-13;
/M: SY='H';  M=  19, -48, -38, -21, -15, -11,  70, -17,   3, -30, -31, -23, -46,   7,   3, -11, -14,  13,  -9,  17; D=-12;
/I:         I=-12; MD=-13;
/M: SY='Y';  M= -13,  -5, -29, -35,  25, -52,  52, -13, -20,  16, -25, -24, -54, -28, -27, -30,  -4, -15, -35,  57; D=-12;
/I:         I=-12; MD=-13;
/M: SY='G';  M= -19, -77, -23, -43, -78,   3, -63, -57,  -4, -54, -66, -23,   1, -17, -15, -16, -58, -58, -79, -71; D=-12;
/I:         I=-12; MI=0; MD=-13; IM=0; DM=-13;
/M: SY='P';  M= -16, -53,   3,  20, -55,  37, -35, -53,  12, -53, -43, -17,  67,  10,   8,  -4, -23, -50, -51, -47;
/M: SY='P';  M= -26, -51,  41,  13, -52, -39, -30, -32,  27, -50, -42,  22,  49, -22,  39,   0,  -4, -37, -56, -43;
/M: SY='I';  M=  -9, -43, -30, -46,   3, -54, -47,  45, -46,  37,  21, -47, -28, -14, -47, -40, -10,  41, -48, -28;
/M: SY='G';  M=  26,  40, -20, -41, -19,  60,   8, -32, -39, -29, -38, -27, -42, -37, -45,  14,   3, -21, -50, -41;
/M: SY='V';  M= -32, -44, -57, -52, -22, -59, -54,  59, -50,  24,  13, -51, -51, -48, -51, -44, -28,  60, -52, -31;
/M: SY='I';  M= -35, -46, -58, -54, -21, -61, -55,  73, -51,  31,  -8, -51, -50, -48, -52, -46, -30,  43, -49, -30;
/M: SY='W';  M= -38, -24, -27, -30, -36, -36,  74, -31, -28, -45, -36,  64, -46,  39, -30, -10, -34, -35, 109, -20;
/M: SY='F';  M= -39, -44, -58, -53,  73, -58, -44,  32, -50,  29,   0, -51, -55, -52, -49, -46, -34,  32, -30,  11;
/M: SY='D';  M= -81,-108, 213,  -9,-122, -48, -53,-118, -56,-115,-113, -16, -80, -55, -73, -57, -61,-112,-151, -87;
/M: SY='A';  M=  83, -35, -40, -32, -49, -22, -41, -39, -34, -41, -34, -34, -39, -31, -23,   5, -24, -26, -49, -44;
/M: SY='H';  M= -85,-108, -52, -53, -81, -88, 272,-118, -62, -83, -53, -31, -86, -40, -50, -63, -82,-117,-153, -19;
/M: SY='F';  M=  25,   4, -46, -42,  56,   0,   3, -17, -42,  20,  -4, -38,  -4, -26, -44, -13,  15, -16, -38, -20;
/M: SY='D';  M= -81,-107, 213,  -8,-122, -74, -52,-118, -55,-115,-113,   4, -80, -54, -72, -57, -60,-112,-152, -87;
/M: SY='L';  M= -36, -10, -50, -47,  19, -54, -43,  36, -45,  45,  29, -43, -48, -43, -46, -31,  38,  -2,  10,  -6;
/M: SY='W';  M= -28, -52, -30, -29, -36, -41,   5, -49, -10, -47, -37,  54, -48,  -6,  75, -29,  -9, -48,  75,  21;
/M: SY='D';  M=   5, -45,  50,   9, -23, -37, -17, -32, -22, -36, -39,  24,  26,   2, -13, -15,  49, -37, -58, -40;
/M: SY='P';  M=   2, -48,   8,  18, -16, -19,   7, -19,   0, -10, -33,   2,  54, -29, -35,  -5,  21, -26, -46,  20;
/I:         I=-25; MD=-26;
/M: SY='E';  M= -33, -61,  15,  41,   3, -40, -14, -36,  -1, -32, -46,  -2, -51, -31,   1, -23, -43, -52,   8,  29; D=-25;
/I:         I=-25; MI=0; MD=-26; IM=0; DM=-26;
/M: SY='S';  M= -24, -65, -36,  -1, -23, -60, -56, -43, -55, -29, -21, -12, -63, -51, -60,  21,  16, -55, -72, -18; D=-25;
/I:         I=-25; DM=-26;
/M: SY='P';  M= -31, -63,  11, -34, -65,  46, -51, -60, -48, -47, -54, -38,  47, -14, -56, -12,  -8, -39, -64, -59; D=-25;
/I:         I=-25; DM=-26;
/M: SY='S';  M= -20, -11,  17,  -5, -33,  -2, -37, -50,  -1, -42, -46,  23, -19, -30, -13,  49,   1, -26, -61, -46; D=-25;
/I:         I=-25; DM=-26;
/M: SY='G';  M= -24,  10, -33,   4, -49,  58,  -7, -54,  18, -51, -41, -27,  23,  11,  28, -15, -36, -42, -46,  -6;
/I:         I=-23; MI=0; MD=-24; IM=0; DM=-24;
/M: SY='N';  M=   9, -47, -16, -35,  -2,   3,  16,  -2, -33,  -9, -31,  55,  46, -33, -23, -18, -29, -24,  11,  21;
/M: SY='N';  M= -28, -11,   6, -34, -35, -23, -12,  14, -33,   7,  -6,  44, -42, -31, -38,  42,  36, -16, -55, -15;
/M: SY='H';  M= -30, -46, -26, -28, -43, -34, 113, -52, -30, -34, -32,  16, -41, -21, -28,  51, -26, -49, -67, -20;
/M: SY='G';  M=  17, -46, -37, -45, -54,  84, -43, -58, -39, -55, -45, -24, -41, -37, -28,   1, -21, -49, -48, -49;
/M: SY='T';  M= -21,  65, -36, -35, -40, -41, -38, -32, -33, -32,  46, -25, -38,   4, -39,  16,  78, -26, -59, -38;
/M: SY='P';  M= -25, -55, -43, -33, -17, -25, -40, -30, -38, -37,  45, -44, 100, -39, -46, -14, -30,   6, -49, -15;
/M: SY='F';  M= -41,  -6, -58, -53,  85, -55, -42,   3, -49,  17,  32, -50, -55, -53, -48, -45, -21,  22,  16,   5;
/M: SY='R';  M=  16, -48, -12, -28, -12, -39,  21, -46,   2, -31, -35, -10, -45, -11,  68,  24, -30, -41,   2,  27;
/I:         I=-17; MD=-18;
/M: SY='Q';  M= -22, -52, -36, -14,  41, -46,  28, -30, -12, -34, -12, -31, -46,  72,  48, -22, -27, -27, -37,  15; D=-17;
/I:         I=-17; MD=-18;
/M: SY='L';  M= -32, -65, -73, -69, -42, -53, -63,  21, -68,  27,  11, -67, -71, -62, -68, -13, -51, -11, -65, -15; D=-17;
/I:         I=-17; MI=0; MD=-18; IM=0; DM=-18;
/M: SY='I';  M=  29,  29, -46, -58, -45, -56, -35,  31, -58,  -7, -34, -57, -25, -56, -61, -45, -44,   3, -62, -15; D=-17;
/I:         I=-17; DM=-18;
/M: SY='A';  M=  37,  -7, -16, -36, -16, -40, -21, -41,   1, -35, -40, -37,  18,  -5, -18,  15,   8, -10, -53,  -7; D=-17;
/I:         I=-17; DM=-18;
/M: SY='E';  M= -35, -54,  39,  72, -56, -44, -11, -54,   3, -44, -44,   7,  33,  21,  -5, -29, -23, -50, -56, -44;
/I:         I=-21; MD=-22;
/M: SY='E';  M= -21,  31,   2,  43, -15, -58, -24, -23, -23, -19, -15, -15, -53, -12, -45, -32, -31, -33, -57,  12; D=-21;
/I:         I=-21; MD=-22;
/M: SY='C';  M= -22,  74, -67, -71,  -8,  26, -18, -67, -67, -31, -59, -39, -73, -68, -72, -40, -40, -62, -74, -61; D=-21;
/I:         I=-21; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='Q';  M= -22, -58, -49, -17, -43, -36, -12,   1, -12,  17,   1,  -2, -57,  24,   4, -26, -33,  -7,  -7, -22; D=-21;
/I:         I=-21; DM=-22;
/M: SY='I';  M= -11, -50,  10, -42, -24,  24, -11,  36, -24,  24,  -6, -39, -22, -10, -46, -30, -36,   5, -52, -37; D=-21;
/I:         I=-21; DM=-22;
/M: SY='W';  M= -34, -50,  32,   5, -40, -11,  22, -25,  13,  -7, -17,  15,   5,   1,  14,  16, -23, -20,  59, -11;
/M: SY='P';  M=  10, -49,  -7,   4, -49,  -1, -37, -37,  -5, -23, -36,  21,  74, -16, -37,   2,  -6,  -1, -54, -46;
/M: SY='F';  M=  -7, -47,  11,  16,  50,  -5, -13, -33,  32, -15, -32,   1, -44, -12,   6, -19, -32,  -1, -39,  -9;
/M: SY='H';  M=  -4, -48,  39, -20, -50, -26,  62, -51,  16, -40, -38,  41, -12,  15,  35,  -9,  -6, -47, -59, -34;
/M: SY='Y';  M= -35, -13, -47, -47, -11, -50, -30,  39, -43,  21,  -3, -20, -51, -38, -43,   6, -13,  16, -26,  76;
/M: SY='V';  M=  30,  35, -48, -44,  -5, -43, -46,  15, -43,  18,  -8, -20, -48, -42, -46, -10,   3,  45, -50, -17;
/M: SY='C';  M= -26,  76, -41, -33, -15, -47,  31,  -9, -34,  -8,   2, -35, -16,  57, -34, -14, -18,  14, -41,  45;
/M: SY='I';  M= -18, -46, -58, -53,  16, -58, -51,  67, -50,  36,  13, -51, -50, -47, -51, -45, -32,  27, -44, -25;
/M: SY='G';  M=  -5, -49, -37, -48, -56,  92, -44, -62, -42, -58, -48, -24, -41, -40, -50, -22, -40, -55, -47, -51;
/M: SY='I';  M= -13, -45, -56, -52, -22, -57, -52,  66, -49,  34,   2, -49, -49, -46, -51, -42, -11,  38, -49, -30;
/M: SY='R';  M= -11, -51, -33, -24, -50, -26, -26, -52,  -5, -48, -38, -10, -45,  29,  86,  30, -30, -46, -50, -37;
/M: SY='D';  M=   4, -46,  46,  13, -51,   7,  -9, -48,  -1, -42, -41, -20, -25,  15,  23,  28,  18, -32, -56, -40;
/M: SY='W';  M=  -2,  -9, -44, -16,  19,   6,  19,   7, -39,  14,  -2, -39,  20,  -7, -29, -22,  -8,  25,  26,  -6;
/I:         I=-22; MD=-23;
/M: SY='D';  M=   2,   2,  57, -16, -49,  10, -14, -35, -32, -25, -20,  24, -43, -30, -22,  36,  -6, -43, -60, -22; D=-22;
/I:         I=-22; MD=-23;
/M: SY='N';  M= -23, -50,  -8, -16, -11, -37, -28, -34,   7, -38, -41,  70,  39,  10,   8,  -9,  -8, -47, -55, -15; D=-22;
/I:         I=-22; MD=-23;
/M: SY='T';  M= -11, -45,   3,  21, -49,  31, -39, -44, -24, -46, -17, -14, -24, -32, -40,   8,  59, -27, -57, -25; D=-22;
/I:         I=-22; MD=-23;
/M: SY='E';  M=  -2, -55, -13,  61, -32, -30, -33, -49,   0, -19, -39, -34,  25,  37,   8, -31, -15, -46, -51, -23; D=-22;
/I:         I=-22; MD=-23;
/M: SY='A';  M=  37, -48,   2,  -3,   2, -25,  26, -48,  23, -46, -39, -31,  -8, -27,  29,  -7, -16, -41,   2, -14; D=-22;
/I:         I=-22; MD=-23;
/M: SY='L';  M= -23, -54,   1,   8,  -9, -55, -36, -31,   2,  37, -25, -43, -25,  12,   2, -32, -40, -35, -43,  32; D=-22;
/I:         I=-22; MD=-23;
/M: SY='F';  M= -49, -71, -45, -29,  61, -48, -57, -38, -65, -30, -48, -68, -76, -68, -44, -65, -61, -31,  30,  31; D=-22;
/I:         I=-22; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='D';  M=  -3, -69,  43,  13, -45, -40,  -3, -73,  -8, -70, -65,   4, -59, -42, -20, -38, -50, -67, -79, -60; D=-22;
/I:         I=-22; DM=-23;
/M: SY='Y';  M=  -7, -54,   2,   3, -10, -52,  -2,  20, -13,  -6, -30, -20, -50,  -6,  24, -37,  -1, -13, -43,  39; D=-22;
/I:         I=-22; DM=-23;
/M: SY='A';  M=  54,  -5,  25, -24, -36, -35, -41,   7, -39,  24, -24, -36,  -9, -35, -43, -11, -28,  -4, -51, -38;
/M: SY='R';  M=  -1, -50,  17,  17, -50, -32,  13, -50,  54, -37, -38,   1, -40,  -1,  57, -29, -32, -35, -51, -37;
/M: SY='E';  M=   2, -49,  35,  41, -27, -30, -29, -33,  25, -47, -40,   2, -23,   9,  33,   5,  -8, -43,  -7, -23;
/M: SY='H';  M= -30,  22, -38, -12,  27, -30,  34, -14,  11,  30,  -8,  14, -48,  -2,   9,  -7, -23, -17, -42,   9;
/M: SY='G';  M= -11, -47,  -8, -29, -54,  77, -35, -58, -15, -57, -46,  46, -26, -22, -41,  -5, -33, -53, -51, -48;
/M: SY='V';  M= -12, -11, -52, -49,  33, -38, -13,  51, -45, -13,  12, -27, -49, -46, -29, -25,  -8,  53, -46, -24;
/M: SY='K';  M=  -9, -47, -12,  12, -43, -32,  10, -21,  36, -25, -34,  20, -11,  14,  31,  -7,  29, -31,  27, -19;
/I:         I=-26; MD=-27;
/M: SY='Y';  M=   6, -48, -51, -48,  27, -51,  -4,  37, -44, -16, -21, -46, -51, -19, -45, -27, -23,  33,  30,  64; D=-26;
/I:         I=-26; MI=-27; MD=-27; IM=-27; DM=-27;
/M: SY='F';  M= -30, -47, -55, -50,  50, -57, -12,  36, -46,  22, -16, -49, -54, -29, -19, -44, -23,  32, -32,  40; D=-26;
/I:         I=-26; DM=-27;
/M: SY='T';  M= -24, -45,  18,  22,  -4, -42, -17, -38, -11,  -4, -35, -27,   5, -29, -26,  26,  49, -35,  30,   6; D=-26;
/I:         I=-26; DM=-27;
/M: SY='M';  M=  35, -18,  43, -20, -40, -18, -33, -29, -35, -25,  86, -16, -42, -31, -39,   6, -29, -19, -55, -36; D=-26;
/I:         I=-26; DM=-27;
/M: SY='H';  M= -25, -52,  42,  25, -21, -35,  53, -24,   1, -18, -35, -17, -26, -11,  35, -23,   3, -29, -51,  13; D=-26;
/I:         I=-26; DM=-27;
/M: SY='D';  M= -17, -52,  63,  56, -50, -42,  41, -49, -23, -26, -15, -11, -37,  20, -16, -18, -22, -36,  -8, -23; D=-26;
/I:         I=-26; DM=-27;
/M: SY='M';  M= -34,  42, -57, -52,  14, -57, -48,  51, -48,  18,  55, -49, -51, -47, -49, -44, -31,  45, -48, -27;
/M: SY='D';  M=  -9, -48,  63,   2, -43, -10,  16, -30, -26, -14, -38,  26, -41,  16,   1,  -6,  14, -41,   7,   0;
/I:         I=-28; MD=-29;
/M: SY='E';  M=   5, -21,  16,  41, -45, -35,   9, -48,  30, -33, -13, -19, -15,  -8,  27, -15,  -1, -44, -50,   8; D=-28;
/I:         I=-28; MD=-29;
/M: SY='Y';  M= -32, -57, -36, -43, -20, -58,  27, -19,  -4,  19,  28, -45, -56,  18,   2, -34, -13, -13,   9,  28; D=-28;
/I:         I=-28; MD=-29;
/M: SY='G';  M= -29, -58,  11, -31, -45,  59,   1, -66, -24, -63, -35,  -7, -31, -11, -49,  12, -31, -61, -61, -53; D=-28;
/I:         I=-28; MI=-29; MD=-29; IM=-29; DM=-29;
/M: SY='I';  M= -18, -47,  -8, -33,  -6, -52,  -3,  37, -42,  25,  24,  -4,   7, -26, -16, -25, -24,  27, -11, -32; D=-28;
/I:         I=-28; DM=-29;
/M: SY='D';  M=  21, -46,  44,   0, -47,  15,   9, -28,  -5,  -9, -36,  15,  19,  -6, -25,  -3, -10, -19, -56, -41;
/M: SY='R';  M=  20, -48,  -7,  18, -47,  10, -33, -46,  26, -33, -13,  -8,  19,   3,  36, -11,  -7, -34,  20, -24;
/M: SY='V';  M=  -3, -44, -29, -41, -14, -48,  -7,  39, -39,  -4,   7, -18,  11, -14, -19, -18,  20,  43,  20, -15;
/M: SY='M';  M=  14, -11, -52, -29,  -9, -50, -44,  44, -35,  34,  52, -47, -48, -29, -34, -39, -31,  26, -47, -30;
/M: SY='E';  M=  10, -47,  36,  48, -32, -30, -29, -48,  27, -35, -41,  29,  -8,   3,  -3,  -9,  -8, -36, -54, -41;
/M: SY='E';  M=   2, -49,   5,  45,   3, -22,  -9, -39,   2, -29,  44, -18, -14,  36,  18, -13, -17, -29,   8, -32;
/M: SY='I';  M=  30, -41, -47, -43,  -2, -44, -46,  45, -19,  18,  -1, -19, -45, -40, -43, -21,  22,  21, -48, -32;
/I:         I=-22; MD=-23;
/M: SY='L';  M= -13, -49,  13, -15, -14, -50, -37,  21,   0,  36,  -4, -21,  -6,   6,  22, -31, -34, -12, -48, -16; D=-22;
/I:         I=-22; MD=-23;
/M: SY='D';  M=  25, -50,  42,  37, -56, -13,  -2, -53,   2, -46, -45,  11,  -8,   7, -11,   2, -31, -47, -59, -45; D=-22;
/I:         I=-22; MD=-23;
/M: SY='R';  M= -10, -53, -29, -39,  35, -51,  37, -16,  -1,  -5, -31, -27, -53, -15,  41, -14, -18, -15,  -6,  20; D=-22;
/I:         I=-22; MD=-23;
/M: SY='I';  M= -30, -51, -64, -59,  10, -41, -57,  41, -57,  33,   0, -58, -59, -55, -57, -51, -28,  35, -53, -34; D=-22;
/I:         I=-22; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='D';  M=   4, -67,  24,  -9, -72, -13,   2, -69,  -4, -57, -61,  -6, -61, -21,  -3, -19, -50, -54, -76, -60; D=-22;
/I:         I=-22; DM=-23;
/M: SY='G';  M=  -5, -53,  13, -10, -58,  36, -10, -57,   9, -56, -47,  21, -26,  21,  16,  -3, -17, -41, -58, -47; D=-22;
/I:         I=-22; DM=-23;
/M: SY='D';  M=  -4,  18,  38, -17, -33,  19,  18, -20,  -5, -33, -14,  21, -19,   8, -22, -13,  19,  11, -58, -38;
/M: SY='D';  M= -30, -14,  70,  -3, -53,  14, -11, -52,   8, -36, -23,   5, -41,   7,  34, -27,   5, -48, -59, -41;
/M: SY='P';  M= -31,   4, -29, -32, -13,  -2,  38, -27,   1, -10, -32,  -7,  72, -17,  13, -23, -11, -26,  -5,  17;
/M: SY='V';  M= -17, -43, -57, -52,  -4, -58, -53,  56, -49,  25, -11, -51, -51, -48, -50, -42, -29,  58, -49, -11;
/M: SY='Y';  M= -43, -54, -40, -41,  15, -49,  82, -24, -37, -27,  23, -36, -51, -31, -33, -38, -39, -37,  21, 100;
/M: SY='L';  M= -37, -10, -58, -51,  11, -59, -46,  32, -51,  63,   2, -54, -55, -46, -49, -47, -33,  29, -45, -25;
/M: SY='T';  M= -19, -35, -29, -32, -44, -31, -36, -38, -30, -43, -38, -18, -34, -28, -36,  67,  74, -30, -58, -39;
/M: SY='I';  M= -38, -46, -58, -54,  55, -59, -49,  63, -50,  13, -12, -50, -52, -51, -51, -45, -32,  35, -35,  11;
/M: SY='D';  M= -56, 114, 201, -16,-117, -77, -58,-115, -60,-110,-108, -22, -85, -60, -77, -58, -61,-105,-151, -89;
/M: SY='I';  M= -19, -44, -56, -50, -22, -56, -47,  55, -47,  35,  52, -49, -49, -44, -48, -31, -16,  39, -49, -29;
/M: SY='D';  M= -82,-108, 214,  -8,-122, -75, -52,-118, -56,-115,-113, -16, -80, -54, -73, -57, -61,-112,-153, -87;
/M: SY='C';  M=  26,  60, -49, -47, -13,  26, -52, -13, -45, -27, -27, -41, -49, -45, -48, -30, -29,  59,   6, -38;
/M: SY='L';  M= -40, -10, -58, -51,  42, -59, -44,  24, -51,  64,   2, -54, -56, -47, -49, -48, -35,   7, -39, -19;
/M: SY='D';  M= -23, -54,  92, -10, -59, -36,  -1, -55, -30, -56, -51, -14,  50, -29, -38,   2, -29, -53, -68, -44;
/M: SY='P';  M=  29, -52, -38, -13, -54, -21, -41, -27, -34, -49, -39, -39,  96,  -6, -43,   8, -28, -33, -51, -50;
/M: SY='A';  M=  54,  -1, -37, -35, -44,  20, -20, -27, -35, -26,   1,  -4, -17, -20, -30,  28,  10, -25,  -6, -28;
/M: SY='Y';  M= -16,  17, -15,  -6,  52, -49,  14,  -2, -39,  -7, -24, -24, -50,   2, -40, -28,  -7,  25,  31,  52;
/I:         I=-32; MD=-33;
/M: SY='A';  M=  73, -37, -44, -37, -42, -29, -42,  -9, -38, -22,  42, -38, -41, -34, -41, -20,  -8,   5, -50, -40; D=-32;
/I:         I=-32; MI=-33; IM=-33; DM=-33;
/M: SY='P';  M= -39, -64, -40, -29, -58, -41, -43, -45, -36, -56, -43, -46, 117, -40, -48, -37, -32, -35, -52, -56;
/M: SY='G';  M=  33,  -6, -38, -43, -53,  79, -43, -55, -40, -53, -44, -25, -41, -37, -46,   7, -34, -46, -48, -48;
/M: SY='T';  M= -18,  10, -42, -42, -33, -48, -49,  -7, -39, -23, -23, -34, -42, -43, -44, -22,  68,  63, -61, -37;
/M: SY='G';  M= -12, -44, -34, -40, -52,  72, -39, -56, -37, -55, -46, -21,  -7, -32, -43,  56, -25, -49, -50, -46;
/M: SY='T';  M=  46, -35, -33, -33, -43, -20,  -8, -36, -32, -39, -34,   0, -36, -33, -39,   6,  74, -27,   7, -39;
/M: SY='P';  M= -22, -60, -40, -30, -52, -42, -41, -13, -34, -49, -17, -44, 109, -37, -10, -25, -14, -43, -50, -21;
/M: SY='E';  M=  33,  -8, -29,  44, -43, -19, -39, -22, -30, -32, -30, -35, -39,  14, -36,   3,  -7,  43, -54, -41;
/M: SY='P';  M=  31, -18, -41, -22, -24, -31, -42,   7, -32, -26, -32, -38,  70, -34,  12,   3,   4,   4, -51, -42;
/M: SY='G';  M= -12, -14, -23, -45,  14,  70, -22, -31, -39,   4, -33, -30, -46, -39,  -1, -29, -38, -21, -40,  13;
/M: SY='G';  M= -22, -50, -37, -49, -56,  94, -44, -64, -43, -59, -48, -23, -41, -40, -50, -22, -41, -57, -47, -51;
/M: SY='L';  M= -22, -44, -57, -49,   1, -56, -47,  29, -47,  54,  16, -53, -32, -45, -30, -45, -33,  36,  45, -25;
/M: SY='T';  M= -26, -42,   3,  -1, -39, -20, -35, -38, -31, -18, -35, -24,  31, -15, -38,  41,  64, -33,  13,   7;
/M: SY='P';  M= -29, -48, -25, -39,  17, -32, -34, -21, -40,  27,  -2, -40,  52, -37, -43,  16,   7, -30,  41,  50;
/M: SY='R';  M=   7, -50,   7,   5, -42,  -9,  19, -38,  -7, -38, -37,   5,  -3, -20,  67,   0, -22, -43,  -4,  14;
/M: SY='E';  M= -26, -21,   8,  67, -20, -47,  -6,  -7, -13, -24, -34, -19, -36,  42,   0, -19,  -1,  -1, -52, -38;
/M: SY='V';  M=  27, -41, -47, -45, -16,  32, -45,  13, -43,  18,  27, -39, -46, -40, -46, -12, -17,  33, -49, -35;
/M: SY='H';  M= -16, -47,  -5,  22,  15, -50,  47,  -6, -22,  37,  32, -37, -46, -17,  18, -31, -35,  -8, -47, -25;
/I:         I=-28; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='Y';  M=  18, -46, -22,  21,  21, -16, -16, -25,  12,  -6, -31,   6,   7,   6,   6,  -2, -25, -28, -38,  31;
/M: SY='I';  M=   3, -44, -56, -51,  19, -54, -49,  59, -49,  36,  18, -49, -50, -45, -49, -33, -31,  25, -44, -26;
/M: SY='C';  M=   6,  37, -37, -47,   8, -51, -15,  33, -46,  37,  33, -46, -50, -43, -47, -26, -18,  30, -48, -28;
/M: SY='E';  M= -20, -52,  17,  59, -51, -37,   9, -50,  27, -35, -22,  -9, -37,  12,  49, -29, -13, -35, -53, -39;
/M: SY='R';  M=   8,  18, -36,  -6, -38,  21,  17, -18,   4, -14,  19, -13,  -3,   2,  40, -14, -18, -25, -46,  12;
/M: SY='L';  M= -11,  -6, -56, -50,  -5, -41, -49,  47, -39,  49,  -9, -51, -52, -46, -49, -43, -31,  38, -48, -29;
/M: SY='H';  M=  35,  17, -18, -22, -14, -21,  45,  -1,   4, -11, -28, -21, -43,  19,   1,   0, -14,  -2, -48,   4;
/M: SY='E';  M=  21, -23,  25,  28, -49,  22, -10, -50,  18, -37, -39, -16,  -9,  25,  20, -17, -25, -44, -49,  -7;
/I:         I=-24; MD=-25;
/M: SY='S';  M= -10, -42, -34, -21, -41, -37,  28, -15,  -3,   3, -16,  -5, -41, -13, -35,  52,  42, -25, -57, -36; D=-24;
/I:         I=-24; MD=-25;
/M: SY='G';  M= -32, -62,  -1, -30, -66,  58, -49, -68,   2, -54, -57,  -1, -12, -17, -35, -24, -29, -64, -63, -59; D=-24;
/I:         I=-24; MI=0; MD=-25; IM=0; DM=-25;
/M: SY='K';  M= -35, -47,   9, -22, -44, -39, -28, -20,  60,   0, -33,  45, -26,  -1,  23,   3, -15, -39, -52, -38;
/M: SY='L';  M= -24, -42, -54, -49,  -3, -56, -47,  28, -48,  53,  -9, -25, -32, -45, -48, -42, -11,  46, -49, -29;
/M: SY='V';  M= -12,   6, -45, -38, -32, -49, -43,  39, -16,  -2,   2, -38, -46,  19,  16,   4,   9,  44, -53, -34;
/M: SY='G';  M=  26,  -5, -38, -41, -45,  62, -23, -31, -39,  -7, -19, -17, -42, -35, -44,  28, -15, -15, -50, -43;
/M: SY='M';  M=  40,  30, -51, -44,  13, -16, -42,  12, -43,  24,  55, -43, -47, -40, -45, -32, -30,  15, -46, -30;
/M: SY='D';  M= -39, -53, 101,  28, -60, -38, -26, -59, -26, -56, -55, -10, -38, -24, -35, -10, -30, -55, -72, -44;
/M: SY='I';  M= -35, -43, -57, -52,   8, -59, -51,  52, -50,  44,  -8, -52, -52, -48, -50, -45, -19,  47, -47, -27;
/M: SY='V';  M=  35,  -9, -50, -44, -32, -44, -49,   3, -43, -18,  34, -24, -48, -43, -45, -31, -25,  70, -56, -36;
/M: SY='E';  M= -33, -54,  -4,  98, -55, -49, -27, -57, -14, -49, -46, -30, -29,  -7, -25, -30, -34, -50,   4, -45;
/M: SY='V';  M= -32,  13, -54, -49,  23, -56, -45,  16, -47,  23,  13, -49, -52, -47, -47, -40,  -2,  61, -42,  28;
/M: SY='N';  M=  29, -39,   0, -18, -49, -24, -24, -46, -25, -51, -41,  85, -42, -24, -33,  35,  -9, -42, -61, -44;
/M: SY='P';  M= -38, -64, -39, -28, -58, -41, -43, -47, -36, -57, -43, -45, 117, -39, -48, -24, -19, -51, -52, -56;
/M: SY='T';  M=   7,  -6,   4, -18, -15, -31, -37,   5, -21,   5, -28,  -8,  28,  15,   6,  11,  33, -10, -51, -36;
/I:         I=-32; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='Y';  M= -42, -48, -48, -33,  29, -54,  -6, -13, -24,  44, -14, -47, -25, -36,   9, -43, -37, -17, -21,  79;
/M: SY='D';  M= -13, -52,  97,   7, -59,  16, -29, -39, -29, -55, -52, -12, -40, -28, -38, -27, -31, -52, -68, -44;
/M: SY='H';  M= -17, -20, -20,  20,  -6, -30,  41,  29, -18, -23, -27,   3,  16,  21, -11,  10,  -6,   4, -50,  -9;
/M: SY='D';  M=  10, -47,  56,   5, -51,   6,   2, -47, -10, -41, -42,  18,  -7, -16,  22,  14,   2, -26, -59, -41;
/M: SY='N';  M= -23, -48,  36,  22, -52,  31,  11, -49, -16, -42, -42,  48,  -4,  22, -15,  12, -28, -24, -57, -42;
/M: SY='R';  M= -11, -49,   4,   2, -40, -46,  18,  25,   6, -15,  22,   1, -43,  17,  50, -16, -13,  -1, -52, -33;
/I:         I=-25; MI=0; MD=-26; IM=0; DM=-26;
/M: SY='T';  M= -27, -45, -22, -18, -51,  -5,   9, -44, -39, -47, -43, -28, -42, -40, -46,   3,  79, -27, -68, -46; D=-25;
/I:         I=-25; DM=-26;
/M: SY='A';  M=  61, -19, -42, -23, -50, -13, -45, -36, -39, -43, -38, -36, -25, -35, -44,  34, -20,   8, -56, -46; D=-25;
/I:         I=-25; DM=-26;
/M: SY='R';  M= -39, -51, -25, -16, -18, -41,  -5,   7,  24,  20,  20, -11, -48, -13,  51, -21, -21, -11, -50, -34; D=-25;
/I:         I=-25; DM=-26;
/M: SY='L';  M=  32, -42, -13, -17, -32, -44, -43, -13, -40,  36,   7, -11, -48, -24, -26, -32,   8,  22, -54, -37; D=-25;
/I:         I=-25; DM=-26;
/M: SY='A';  M=  67, -36, -39, -35, -44,   1, -43, -19, -36, -31,  -8, -32, -38, -34, -41, -15,  43,  -5, -51, -42;
/M: SY='A';  M=  70, -36, -42, -36, -41,  -9, -43, -12, -37, -33, -30, -36, -41, -35, -42,  -2,   0,  24, -49, -11;
/M: SY='R';  M= -15, -49,   3,  -1, -29, -32,  23, -48,  32, -39, -37,  26, -42,   0,  64,  -1,   6, -34, -52, -35;
/M: SY='L';  M=  -3, -11, -53, -47,  22, -53, -45,  23, -47,  53, -10, -48, -51, -27, -47, -29,   2,  28, -44, -25;
/M: SY='I';  M=  37,   0, -48, -45, -16,  15, -47,  39, -43,   3,  21, -40, -45, -41, -47, -22, -12,  28, -49, -35;
/M: SY='W';  M=  -6,  53, -12, -22,  18, -27,  28, -29, -37,   7,   5, -30, -52, -38,   8, -39, -26,   7,  81,  21;
/M: SY='E';  M=   1, -14,  32,  42, -47, -38,  29, -51, -23, -48, -42,  -2, -39,  20,   9,  31,  -5, -45, -53,   8;
/M: SY='L';  M= -24, -10, -57, -52,   9, -57, -45,  43, -49,  46,  36, -51, -53, -45, -49, -45, -10,   9,  21,   7;
/M: SY='L';  M=  21, -42, -52, -47, -27, -18, -45,  22, -46,  42,  32, -46, -49, -42, -47, -29,   5,  20, -50, -34;
/M: SY='C';  M=   1,  30,  -8,  -5, -21,  11,  28, -27,  -1,  -2, -33,   0, -47, -15,  27,  -2, -17, -20,   2,   6;
/M: SY='W';  M=   7,  35, -44, -26, -27,   4,  -1, -27,  -1,  -3,  -1, -22, -49, -14, -29,  24,   3, -29,  36, -40;
/M: SY='W';  M=  12,  22, -53, -44, -15, -38,  20,  -3, -23,  10,  47, -31, -53,   9, -15, -32, -40, -12,  63, -17;
/M: SY='F';  M=   4, -16, -54, -48,  33,  -9, -47, -17, -13,  15, -29, -33, -27, -25,  11, -27, -40,  12, -48, -21;
/M: SY='G';  M= -21, -64,   7, -23, -44,  33, -50, -30,  23, -27, -51, -40, -22, -13, -14, -34, -49, -56, -62, -38;
/M: SY='Q';  M= -35, -12,  -6,   3, -48, -64,   1, -34,   5, -55, -57,  -6, -41,  16,  -7, -28, -42, -34, -76, -59;
/M: SY='T';  M= -28, -69, -59, -33, -65, -51,  -7, -58,  -8, -31, -32, -53,   2, -27, -27, -15,  25, -32, -77, -34;
/M: SY='L';  M= -45, -79, -33, -39, -37, -45, -72, -25, -64,   5, -52, -71, -81, -43,  -3, -68, -22, -27, -82, -65;
/M: SY='L';  M= -57, -82, -49, -15, -42, -34, -35, -60, -36,   2, -16, -35, -81, -65, -32, -54, -49, -45, -82, -38;
/M: SY='G';  M= -60,-120, -18, -94,-122, -18, -48, -82, -99,-117,-110, -90,-111, -37, -67, -94,-105,-114,-124,-110;
/M: SY='R';  M=-117,-128, -72,-115, -58, -63,-113,-111,-102, -66,-108, -53,-130,-110, -24,-114,-115, -78,-127,-110;
/I:         E1=0; IE=-105; DE=-105;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 229 in 229 different sequences
Number of true positive hits 229 in 229 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] window20
Author [info] PS_Langendijk_Genevaux
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
229 sequences

AGMT_PYRHO  (O57839), APAUH_SYNY3 (P72703), APAUH_THEKO (Q5JI38), 
APAUH_THET2 (Q72JK8), APAUH_THET8 (Q5SJ85), ARGI1_ARATH (P46637), 
ARGI1_BOVIN (Q2KJ64), ARGI1_HUMAN (P05089), ARGI1_MOUSE (Q61176), 
ARGI1_ORYSI (B8AU84), ARGI1_ORYSJ (Q7X7N2), ARGI1_PIG   (Q95JC8), 
ARGI1_RABIT (Q95KM0), ARGI1_RAT   (P07824), ARGI1_SCHPO (P37818), 
ARGI1_XENLA (P30759), ARGI2_ARATH (Q9ZPF5), ARGI2_BOVIN (Q58DL1), 
ARGI2_HUMAN (P78540), ARGI2_MOUSE (O08691), ARGI2_RABIT (Q4VK78), 
ARGI2_RAT   (O08701), ARGI2_SCHPO (Q10066), ARGI_AGRFC  (P14012), 
ARGI_AQUCT  (P49900), ARGI_BACCD  (P53608), ARGI_BACSU  (P39138), 
ARGI_BREBE  (Q7M0Z3), ARGI_BRUAB  (P0A2Y1), ARGI_BRUME  (P0A2X9), 
ARGI_BRUSU  (P0A2Y0), ARGI_COCIM  (Q1E180), ARGI_COCP7  (P40906), 
ARGI_EMENI  (Q12611), ARGI_ENTH1  (C4LSS0), ARGI_EREGS  (Q74ZW4), 
ARGI_GLAA1  (A0A2R2JFW7), ARGI_KLULA  (Q6CLS8), ARGI_MEDTR  (G7JFU5), 
ARGI_NEUCR  (P33280), ARGI_PLABA  (A0A509AF89), ARGI_PLAF7  (Q8I384), 
ARGI_SOYBN  (O49046), ARGI_STAAC  (P60086), ARGI_STAAM  (P60087), 
ARGI_STAAN  (P60088), ARGI_STAAR  (Q6GER3), ARGI_STAAS  (Q6G7E9), 
ARGI_STAAW  (Q8NVE3), ARGI_YEAST  (P00812), ARGN1_XENLA (Q91553), 
ARGN2_XENLA (Q91554), ARGN3_XENLA (Q91555), DCSB_STRLA  (D2Z025), 
GBH_ARTS8   (Q8KZT5), GBU1_KLULA  (Q6CIB4), GBUA_PSEAE  (Q9I3S3), 
GDAH_HUMAN  (Q9BSE5), GDAH_MOUSE  (A2AS89), GDAH_RAT(Q0D2L3), 
GDMH_SYNY3  (P73270), GPUA_PSEAE  (Q9I6K2), HUTGL_PSEA7 (A6V2Q0), 
HUTGL_PSEA8 (B7V9J1), HUTGL_PSEAB (Q02PY1), HUTGL_PSEAE (Q9HZ59), 
HUTGL_PSEF5 (Q4KJT9), HUTG_AERHH  (A0KF85), HUTG_AERS4  (A4SSN4), 
HUTG_ALIF1  (Q5E0C4), HUTG_AROAE  (Q5NZY1), HUTG_BACSU  (P42068), 
HUTG_BORBR  (Q7WJ55), HUTG_CHRVO  (P60109), HUTG_CITK8  (A8AJ18), 
HUTG_CLOTE  (Q893K6), HUTG_COREF  (Q8FQ76), HUTG_CUPNH  (Q0KFM5), 
HUTG_CUPPJ  (Q471H6), HUTG_ENT38  (A4W8B2), HUTG_FUSNN  (Q8RFN0), 
HUTG_GEOKA  (Q5L086), HUTG_GEOSW  (C5DA16), HUTG_GEOTN  (A4IMP1), 
HUTG_HAHCH  (Q2SEP7), HUTG_HALH5  (Q9KBE3), HUTG_HALS3  (B0R542), 
HUTG_HALSA  (Q9HQD7), HUTG_KLEAE  (P19452), HUTG_KLEP3  (B5XZ82), 
HUTG_KLEP7  (A6T6K8), HUTG_LEGPA  (Q5X741), HUTG_LEGPH  (Q5ZXM2), 
HUTG_LEGPL  (Q5WYJ0), HUTG_LYSSC  (B1HQK2), HUTG_MACCJ  (B9E7J8), 
HUTG_NOCFA  (Q5Z0G1), HUTG_PARPJ  (B2TFB8), HUTG_PARXL  (Q13PQ0), 
HUTG_PHOLL  (P60110), HUTG_PHOPR  (Q6LQ58), HUTG_PSYCK  (Q1Q9E3), 
HUTG_RALN1  (Q8XW30), HUTG_RHOJR  (Q0S7R0), HUTG_RHOOB  (C1BBD1), 
HUTG_SALA4  (B5F066), HUTG_SALAR  (A9MJF2), HUTG_SALCH  (Q57RG9), 
HUTG_SALDC  (B5FP55), HUTG_SALEP  (B5QX59), HUTG_SALG2  (B5R755), 
HUTG_SALHS  (B4TC42), HUTG_SALNS  (B4SZJ1), HUTG_SALPA  (Q5PG59), 
HUTG_SALPB  (A9MTJ4), HUTG_SALPC  (C0PWX6), HUTG_SALPK  (B5BC36), 
HUTG_SALSV  (B4TQT3), HUTG_SALTI  (Q8Z899), HUTG_SALTY  (Q8ZQR1), 
HUTG_STAA1  (A7X5U0), HUTG_STAA2  (A6U459), HUTG_STAA3  (Q2FEG2), 
HUTG_STAA8  (Q2FVT2), HUTG_STAA9  (A5IVB6), HUTG_STAAB  (Q2YYV4), 
HUTG_STAAC  (Q5HDM3), HUTG_STAAE  (A6QJH5), HUTG_STAAM  (P63570), 
HUTG_STAAN  (P99158), HUTG_STAAR  (Q6GEA1), HUTG_STAAS  (Q6G6Y7), 
HUTG_STAAT  (A8Z523), HUTG_STAAW  (Q8NV63), HUTG_STACT  (B9DLS6), 
HUTG_STAEQ  (Q5HLR4), HUTG_STAES  (Q8CNA3), HUTG_STAHJ  (Q4L8J3), 
HUTG_STRGC  (A8AZ72), HUTG_STRP1  (Q99XQ9), HUTG_STRP3  (P0CZ66), 
HUTG_STRP6  (Q5X9K2), HUTG_STRP8  (Q8NZ45), HUTG_STRPB  (Q1J9E8), 
HUTG_STRPC  (Q1JJJ7), HUTG_STRPD  (Q1JEK0), HUTG_STRPF  (Q1J4B6), 
HUTG_STRPG  (A2RGS6), HUTG_STRPM  (Q48QY8), HUTG_STRPQ  (P0CZ67), 
HUTG_STRPZ  (B5XIY3), HUTG_VIBC3  (A5F1X7), HUTG_VIBCH  (Q9KSQ2), 
HUTG_VIBCM  (C3LLQ0), HUTG_VIBPA  (Q87Q75), HUTG_VIBVU  (Q8DA19), 
HUTG_VIBVY  (P60111), PAH_STRCL   (P0DJQ3), SPEB1_SCHPO (Q10088), 
SPEB2_SCHPO (O42887), SPEB3_SCHPO (Q9C0Y9), SPEB_BACAN  (Q81JT1), 
SPEB_BACCR  (Q814Q2), SPEB_BACSU  (P70999), SPEB_BLOFL  (Q7VRG4), 
SPEB_CHICK  (Q90XD2), SPEB_CHRVO  (Q7P0S6), SPEB_CITK8  (A8APF8), 
SPEB_CROS8  (A7MJQ1), SPEB_ECO24  (A7ZR59), SPEB_ECO27  (B7UHY3), 
SPEB_ECO45  (B7MMC5), SPEB_ECO55  (B7LFJ6), SPEB_ECO57  (P60652), 
SPEB_ECO5E  (B5YQD4), SPEB_ECO7I  (B7NI01), SPEB_ECO81  (B7MZN5), 
SPEB_ECO8A  (B7LYW6), SPEB_ECOBW  (C5A0K6), SPEB_ECODH  (B1XF99), 
SPEB_ECOHS  (A8A477), SPEB_ECOK1  (A1AFC5), SPEB_ECOL5  (Q0TDR4), 
SPEB_ECOL6  (Q8FE36), SPEB_ECOLC  (B1IT67), SPEB_ECOLI  (P60651), 
SPEB_ECOLU  (B7N7I9), SPEB_ECOSE  (B6I775), SPEB_ECOSM  (B1LDE6), 
SPEB_ECOUT  (Q1R791), SPEB_EDWI9  (C5BAV1), SPEB_ENT38  (A4WE75), 
SPEB_ESCF3  (B7LPE7), SPEB_HALH5  (Q9K6B9), SPEB_KLEP3  (B5XUB2), 
SPEB_KLEP7  (A6TDU9), SPEB_METJA  (Q57757), SPEB_NEIG1  (Q5F6R3), 
SPEB_NEIG2  (B4RP98), SPEB_NEIM0  (A9M254), SPEB_NEIMA  (P60653), 
SPEB_NEIMB  (P60654), SPEB_NEIMF  (A1KVF9), SPEB_PHOLL  (Q7N122), 
SPEB_PROMH  (B4F1A3), SPEB_PROMI  (Q7X3P1), SPEB_SALA4  (B5F5K3), 
SPEB_SALCH  (Q57K36), SPEB_SALDC  (B5FUJ0), SPEB_SALEP  (B5QXK5), 
SPEB_SALG2  (B5RE39), SPEB_SALHS  (B4THG3), SPEB_SALNS  (B4T5I5), 
SPEB_SALPA  (Q5PJH7), SPEB_SALPB  (A9N3R6), SPEB_SALPC  (C0PY54), 
SPEB_SALPK  (B5BFP3), SPEB_SALSV  (B4TV53), SPEB_SALTI  (P60655), 
SPEB_SALTY  (P60656), SPEB_SERP5  (A8GIX7), SPEB_SHIB3  (B2U0V8), 
SPEB_SHIBS  (Q31WK0), SPEB_SHIDS  (Q32C02), SPEB_SHIF8  (Q0T0V7), 
SPEB_SHIFL  (P60657), SPEB_SHISS  (Q3YXT4), SPEB_SODGM  (Q2NRD3), 
YHMF_METFE  (P19268)
» more

PDB
[Detailed view]
145 PDB

1CEV; 1D3V; 1GQ6; 1GQ7; 1HQ5; 1HQF; 1HQG; 1HQH; 1HQX; 1P8M; 1P8N; 1P8O; 1P8P; 1P8Q; 1P8R; 1P8S; 1PQ3; 1R1O; 1RLA; 1T4P; 1T4R; 1T4S; 1T4T; 1T5F; 1T5G; 1TA1; 1TBH; 1TBJ; 1TBL; 1WVA; 1WVB; 1XFK; 1ZPE; 1ZPG; 2AEB; 2CEV; 2PHA; 2PHO; 2PLL; 2RLA; 2ZAV; 3CEV; 3DJ8; 3E6K; 3E6V; 3E8Q; 3E8Z; 3E9B; 3F80; 3GMZ; 3GN0; 3KV2; 3LP4; 3LP7; 3M1R; 3MFV; 3MFW; 3MJL; 3MMR; 3NIO; 3NIP; 3NIQ; 3RLA; 3SJT; 3SKK; 3SL0; 3SL1; 3TF3; 3TH7; 3THE; 3THH; 3THJ; 4CEV; 4FCI; 4FCK; 4GSM; 4GSV; 4GSZ; 4GWC; 4GWD; 4HWW; 4HXQ; 4HZE; 4I06; 4IE1; 4IE2; 4IE3; 4IXU; 4IXV; 4RLA; 5CEV; 5RLA; 5YNL; 5ZEE; 5ZEF; 5ZEH; 6DKT; 6LUG; 6LUH; 6NFP; 6Q37; 6Q39; 6Q92; 6Q9P; 6QAF; 6SS2; 6SS4; 6SS6; 6V7C; 6V7D; 6V7E; 6V7F; 6VSS; 6VST; 6VSU; 7ESR; 7EUK; 7EUL; 7EUN; 7EUQ; 7K4G; 7K4H; 7K4I; 7K4J; 7K4K; 7KLK; 7KLL; 7KLM; 7LBA; 7LEX; 7LEY; 7LEZ; 7LF0; 7LF1; 7LF2; 7LOL; 7LOX; 7OI1; 8AUP; 8E5M; 8E5N; 8IUS; 8IUU; 8IUV; 8IUW
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