PROSITE entry PS51415

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General information about the entry

Entry name [info]	XYLOSE_ISOMERASE
Accession [info]	PS51415
Entry type [info]	MATRIX
Date [info]	01-DEC-2008 CREATED; 01-DEC-2008 DATA UPDATE; 27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00156
Associated ProRule [info]	PRU00748

Name and characterization of the entry

Description [info]

Xylose isomerase family profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=402;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=397;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.9636081; R2=0.0077943; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=1519; N_SCORE=13.8; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=583; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-18; D=-100; I=-100; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-105; BD=-105;
/M: SY='G';  M= -20, -46, -12,  10, -51,  72, -30, -53, -26, -49, -38,  -8, -34,  45, -31, -17, -15, -48, -43, -41;
/M: SY='K';  M= -15, -48, -27, -14, -48, -36,  -9, -45,  70, -47, -34, -22,  62,  -7,   9, -26, -26, -43, -43, -37;
/M: SY='T';  M= -23, -37, -26, -21, -40, -35, -30, -36,  38, -38, -31, -17,   4, -19,  31,  15,  63, -29, -49, -34;
/M: SY='M';  M= -29, -40, -44, -34, -24, -40, -25, -11, -28,  14,  99, -36,  49, -25,   3, -12, -26, -14, -42, -24;
/M: SY='E';  M=   3, -44,  -9,  68, -48, -37, -23, -47,  46, -43, -36, -21, -27,   2,  15,  -9, -25, -40, -44, -37;
/I:         I=-28; MD=-29;
/M: SY='D';  M= -47, -64,  63,  49, -69, -52, -36, -69, -31, -64, -61, -27, -44, -27, -40, -39, -42, -63, -74, -55; D=-28;
/I:         I=-28; MI=-29; MD=-29; IM=-29; DM=-29;
/M: SY='H';  M= -53, -68, -45, -41, -42, -55,  97, -61, -44, -33, -39, -36, -55,  -5, -40, -47, -54, -65,  89, -19; D=-28;
/I:         I=-28; DM=-29;
/M: SY='L';  M= -35,  -2,  41, -27,  20, -45,  37, -12, -37,  54,   1, -29, -45, -32, -37, -36, -29, -18, -42, -17;
/M: SY='R';  M= -33, -49, -28, -16, -43, -42,  20, -49,  44, -42, -31, -20, -39,  -7,  87, -27, -31, -43, -43, -28;
/M: SY='F';  M= -41, -38, -55, -50, 102, -50, -35,  -6, -45,  -1,   7, -44, -52, -54, -42, -41, -33, -14, -10,  12;
/M: SY='A';  M=  50, -29, -28, -26, -40,  -4, -33, -33, -27, -36, -31, -19, -31, -23, -32,  45,  43, -23, -47, -35;
/M: SY='F';  M= -10, -18, -50, -45,  60, -48, -43,  16, -42,   0,  12, -43, -47, -45, -42, -34, -16,  58, -32, -10;
/M: SY='C';  M=  49,  80, -36, -36, -43,  46, -39, -41, -35, -39, -34, -26, -39, -33, -40,  -8, -25, -24, -47, -42;
/M: SY='Y';  M= -37, -45, -45, -43,  28, -47, -17, -14, -37,  35,   3, -44, -50, -33, -35, -38, -33, -21,  67,  88;
/M: SY='W';  M= -43, -68, -70, -47,  -7, -41, -70, -40, -39, -38, -41, -63, -46, -39, -43, -49, -55, -55, 166,   6;
/I:         I=-30; MD=-32;
/M: SY='H';  M= -53, -64, -36, -36, -51, -54, 114, -69, -41, -51, -37, -26, -53, -30, -35, -42, -51, -69, -86, -20; D=-30;
/I:         I=-30; MI=-32; IM=-32; DM=-32;
/M: SY='T';  M= -18, -29, -22, -26, -36, -32, -32, -28, -23, -32, -28,  14, -27, -17, -31,  18,  87, -20, -55, -33;
/M: SY='F';  M= -33, -37, -53, -47,  81, -50, -38,  10, -43,   7,  28, -44, -49, -48, -42, -39, -28,  39, -22,   1;
/M: SY='C';  M=  -2,  76,   7, -33, -41,  47, -36, -34, -29, -37, -33,  -4, -39, -32,   2, -18,  21,   3, -51, -40;
/M: SY='W';  M=   1, -50, -36, -14, -23,  24, -37, -41, -28, -39, -17,  19, -39,  23, -33, -12, -35, -45, 130,   6;
/M: SY='Q';  M= -24, -44,  40,  21, -44, -36, -25, -14, -17, -36, -30,   2,  36,  44,   6, -19,  28,  -3, -51, -35;
/M: SY='G';  M=  -5, -42, -33, -42, -42,  84, -38, -45, -37,  -5, -33, -20, -37, -34, -43, -18, -34, -42, -40, -41;
/M: SY='R';  M=  19, -37, -30, -18, -39,  29, -30, -31, -13, -18, -29, -10, -36, -12,  39,  28,   7,   0, -45, -34;
/M: SY='D';  M= -35, -48, 102,   2, -55, -31, -20, -53, -22, -51, -51,  -2, -34, -21, -30, -22, -24, -50, -70, -37;
/M: SY='P';  M= -15, -52, -36, -24, -44, -36, -35, -23, -30, -35,  30, -38, 102,  -1, -39, -29, -25,  -4, -46, -42;
/M: SY='F';  M= -43, -38, -55, -50, 105, -50, -35, -16, -46,  -7, -18, -44, -53, -57, -43, -41, -34, -21,  -7,  14;
/M: SY='G';  M= -16, -44, -31, -43, -50,  90, -38, -58, -37, -53, -42, -17, -35, -34, -44, -16, -35, -51, -41, -45;
/M: SY='D';  M=  19,  -7,  54,  -3, -23,  28, -30, -35, -16, -39, -35, -10,  16, -10, -33,  -7,  -5,  -2, -50, -36;
/M: SY='G';  M=  43, -39, -30, -19, -48,  54, -34, -43, -28, -44, -34, -15,  34,  19, -27, -11, -26, -36, -42, -41;
/M: SY='T';  M= -10, -29, -27, -29, -33, -35, -36, -19, -26, -27, -25, -13, -13, -30, -34,   4,  85,  15, -54, -32;
/M: SY='R';  M=   9, -40, -37, -28,  48, -39, -26, -26,  13,   2,  27, -11, -42, -22,  55, -28, -18, -26, -31,  -6;
/M: SY='Q';  M= -19, -43,  28,  36, -30, -28,  27, -14,   5, -28, -29,  -2,   6,  40,  -7,  -8,  17, -14, -47, -14;
/I:         I=-13; MD=-13;
/M: SY='R';  M= -51, -66, -50, -38,   1, -60, -38, -60,  -5, -53, -46, -42, -59, -28,  74, -46, -50, -57,  29, -22; D=-13;
/I:         I=-13; MD=-13;
/M: SY='P';  M= -33, -69, -21, -38, -43, -49, -51, -56, -45, -64, -53, -36,  89, -47, -56, -19, -26, -59, -62, -61; D=-13;
/I:         I=-13; MD=-13;
/M: SY='W';  M= -58, -82, -83, -63, -22, -57, -77, -53, -55, -52, -54, -77, -63, -54, -58, -64, -68, -53, 146,  13; D=-13;
/I:         I=-13; MD=-13;
/M: SY='D';  M= -36, -58,  33,  -7,  17, -34,  12, -51, -39, -24, -44,  16, -54,  14, -43, -23, -41, -52, -55,  -9; D=-13;
/I:         I=-13; MI=0; MD=-13; IM=0; DM=-13;
/M: SY='G';  M= -34, -61, -43, -38, -65,  40,   5, -67,  17, -63, -51, -33, -31,  21,  -9, -14, -45, -62, -59, -51; D=-13;
/I:         I=-13; MI=0; MD=-13; IM=0; DM=-13;
/M: SY='T';  M= -20, -59, -21, -25, -39,   5, -50, -48, -26, -47, -52, -40,   0, -46, -52,   6,  18, -51, -60,  -4; D=-13;
/I:         I=-13; DM=-13;
/M: SY='D';  M= -45, -58,  65, -11, -63, -45, -20, -59, -37, -59,  -9,  19, -49, -36, -45,  -4,  -3, -57, -79, -51; D=-13;
/I:         I=-13; DM=-13;
/M: SY='P';  M=   7, -57,  -6,  -3, -62, -10, -48, -55, -42, -52, -51, -40,  52, -40, -51,   0,   1, -50, -64, -57; D=-13;
/I:         I=-13; DM=-13;
/M: SY='M';  M= -24, -52, -40, -39, -34, -59, -44,  -9, -51,  15,  80, -54, -56, -26, -50, -51, -42,  -2, -58, -37; D=-13;
/I:         I=-13; DM=-13;
/M: SY='D';  M=  -4, -59,  44,  36, -65, -48, -17, -61, -32, -59, -54, -20, -46,  -7, -26, -17, -19, -48, -70, -52; D=-13;
/I:         I=-13; DM=-13;
/M: SY='R';  M= -12, -55, -46, -30, -45, -44,  -3, -29, -13,   7,  14,   3, -55,  -2,  24, -40, -15, -39, -60, -43; D=-13;
/I:         I=-13; DM=-13;
/M: SY='A';  M=  72, -31, -11, -25, -44,  -4, -33, -35, -25, -36, -30,  -5,  -3, -25,   0, -10, -20, -23, -44, -38;
/M: SY='K';  M= -23, -41, -32,  -8,  -7, -43,   2, -14,  54,  39, -13, -28, -39,  -9,  22, -31, -28, -23, -39, -24;
/M: SY='D';  M=  35, -38,  52, -11, -38, -20,  -6, -33, -10,  -3,  -6,   5, -36,   3,  16,  -5, -23, -23, -48, -17;
/M: SY='P';  M= -31, -49, -28, -15, -46, -38, -27, -42,  61, -44, -33, -23,  63, -13,  47, -27, -26, -25, -42, -36;
/M: SY='V';  M=  40, -32, -44, -36, -26, -35, -41,   0, -35,  -1,  32, -38, -40, -34, -24, -23, -13,  58, -48, -30;
/M: SY='D';  M= -31, -48,  71,  59, -43, -37, -19, -37,  -7, -43, -40,  -4, -30,  -3,  -3, -24, -26, -35, -49,   8;
/I:         I=-30; MD=-32;
/M: SY='A';  M=  45, -48, -36, -33, -44, -42, -50, -20, -48, -40, -20, -48, -53, -45, -51, -27, -36,  12, -54,   4; D=-30;
/I:         I=-30; MI=-32; IM=-32; DM=-32;
/M: SY='A';  M=  61, -31, -35, -30,   0,  -2,  -9,  -4, -31, -18,  -8, -15, -35, -28, -35,   8,   2,   1, -42, -30;
/M: SY='F';  M= -33, -37, -52, -48,  89, -24, -39,  -5, -44,  -4, -15, -43, -50, -52, -43, -38, -29,  37, -18,   4;
/M: SY='E';  M= -16, -48,   4,  76, -47, -40,  59, -50, -10, -41, -34, -20, -27,  24,  11, -23, -29, -44, -49, -30;
/M: SY='F';  M= -36, -41, -44, -35,  75, -47, -30,   6,  17,  10,  29, -35, -45, -32,  27, -36, -31, -19, -22,  -2;
/M: SY='F';  M= -28,   5, -52, -46,  70, -50, -34,  11, -43,  42,  35, -45, -50, -43, -41, -40, -31,  -6, -22,  13;
/M: SY='E';  M=  30, -37,  12,  38, -42, -28,   2, -39, -10, -38, -32, -18, -30,  23,  -2,  22,  28, -31, -47, -19;
/M: SY='K';  M= -29, -45,   1,  41, -41, -40, -25,  -9,  66, -13, -28, -19, -30,  13,   6, -25, -19, -33, -42, -32;
/M: SY='L';  M= -32,  -9, -50, -43, -10, -52, -36,  17, -44,  68,  21, -47, -49, -37, -42, -41, -11,   4, -40, -21;
/M: SY='G';  M= -19, -43,   8, -32, -49,  78, -30, -54, -29, -52, -41,  31, -36,  -2, -25,  -6, -30, -49, -45, -42;
/M: SY='V';  M=  44, -32, -43, -37, -27, -34, -45,  27, -37, -10, -14, -37, -40, -36, -40, -16,  -9,  55, -48, -31;
/M: SY='P';  M= -33, -52,  18,  21, -23, -25,  27, -39,  -8, -39, -31, -28,  78, -23, -30, -28, -28, -41, -28,  58;
/M: SY='Y';  M= -31, -46, -38, -42,  42,  44, -17, -31, -34, -26, -24, -31, -45, -33, -21, -28, -34, -34,  21,  86;
/M: SY='Y';  M= -34, -42, -48, -45,  60, -48, -28,  12, -40,   3, -14, -44, -49, -40, -39, -37, -30,  29,  60,  69;
/M: SY='C';  M= -10, 115, -32, -37, -38, -35, -37, -37, -33, -35, -33,  19, -43, -37, -40,  -5,  48, -28, -62, -41;
/M: SY='F';  M= -42, -39, -55, -50, 102, -50, -35, -15, -46,   5, -16, -45, -53, -55, -43, -41, -34, -21,  31,  13;
/M: SY='H';  M= -73, -96, -40, -40, -69, -76, 261,-106, -50, -70, -41, -19, -74, -28, -38, -51, -70,-105,-141,  -7;
/M: SY='D';  M= -35, -48, 102,   2, -55, -31, -20, -53, -22, -51, -51,  -2, -34, -21, -30, -22, -24, -50, -70, -37;
/M: SY='R';  M=   3, -40,  38,   3, -21, -37, -10,   4, -16, -28, -25,  13, -38, -22,  41, -23,   4,  26, -51, -30;
/M: SY='D';  M= -69, -96, 201,  29,-110, -63, -40,-106, -42,-102,-100,  -5, -66, -40, -59, -45, -49, -99,-138, -75;
/M: SY='L';  M= -22, -37, -51, -45, -13, -53, -44,  49, -44,  49,   0, -47, -46, -40, -44, -40, -25,  39, -42, -23;
/M: SY='A';  M=  45, -35, -37, -32,  -9, -30, -36,  33, -26, -20,   7,  -7, -38, -27,  15,   8, -20,  17, -43, -29;
/M: SY='P';  M=  -7, -54, -13,  -6, -51, -34, -11, -41, -28, -49, -36, -36, 107, -31, -40, -27, -15, -43, -47, -47;
/M: SY='E';  M= -31, -45,  11,  74,  44, -44, -24, -18, -14, -30, -32, -26, -30,  -4,   4, -27, -19, -34, -35, -20;
/M: SY='G';  M=   9, -42,   8, -36, -47,  82, -35, -53, -34, -50, -40, -17, -35, -32, -41, -12, -32, -46, -41, -21;
/M: SY='S';  M=  33,  -9,  29,   3, -43, -14,  -6, -39,  -5, -32, -34,  25, -17, -19,  -9,  34,  14, -31, -51, -35;
/M: SY='T';  M= -16, -32,   7, -23, -40, -16, -28, -35, -24, -39, -34,  17,  11, -22, -31,  55,  59, -28, -53, -34;
/M: SY='L';  M= -17, -41,  27, -11,  26, -45, -32,  13, -35,  46,  -9, -35,  21, -33, -25, -35, -28, -15, -37,  -6;
/M: SY='K';  M=  33, -39, -24,  -2, -45, -12, -10, -41,  36, -40, -30,   4, -33,  34,  35,  -1,   4, -33, -43, -33;
/M: SY='E';  M= -12, -46,  16,  88, -50, -41, -21, -49, -10, -43, -39, -22, -23,  -3, -20, -22,  -7, -41, -48, -40;
/M: SY='R';  M= -26, -39, -28, -26,  17, -35,  -3, -34, -12, -32, -27,  -3, -37, -19,  53,  26,  41, -30, -31,  41;
/M: SY='N';  M= -19, -40,  33,  26, -16,  -9,   5, -13, -15, -18, -13,  48, -36,   8,  -8, -13,   0,  -3, -46,   4;
/M: SY='R';  M=  24, -39,   3,  12, -42, -10,  -6, -37,  27, -39, -31,   9, -33,  18,  28,  13,  -3, -13, -45, -18;
/I:         I=-20; MD=-21;
/M: SY='N';  M= -19, -50, -22, -37, -52, -35,   1, -32, -28, -57, -46,  78, -53, -15,   0, -18, -30, -52, -67, -22; D=-20;
/I:         I=-20; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='L';  M= -47, -50, -64, -58,  28, -25, -50,  -5, -58,  49, -14, -59, -63, -54, -56, -54, -44, -16, -45, -27; D=-20;
/I:         I=-20; DM=-21;
/M: SY='D';  M=   5, -54,  59,  -3, -60, -26, -36, -51, -17, -49, -50,  16, -48,  -8, -40, -32, -36, -23, -70, -50; D=-20;
/I:         I=-20; DM=-21;
/M: SY='E';  M=   4, -54, -24,  33, -54, -50, -20, -15,  10, -45, -41, -36, -44,   9,  -5, -33,   2, -15, -59, -47; D=-20;
/I:         I=-20; DM=-21;
/M: SY='I';  M= -21, -41, -45, -40, -20, -49,  44,  62, -38,   0,  52, -35, -40,  -9, -38, -34, -16,  30, -45, -21;
/M: SY='V';  M=  -3, -35, -43, -38, -23, -32, -44,  38, -36,   7, -10, -36, -40,  -2, -39, -15,  22,  56, -48, -28;
/M: SY='D';  M=  12, -44,  74,  27, -49,  -8, -23, -47,   8, -40, -40, -11, -33, -16,  15, -16, -18, -41, -54, -37;
/M: SY='Y';  M= -31, -43,  -9,  -9, -11, -19,  36,  -4,  11,   7,  22, -28, -41, -21,  38, -31, -29,  11, -31,  47;
/M: SY='F';  M=   6, -39, -50, -44,  60, -46, -39,  42, -42,  29,   0, -43,  -2, -42, -43, -35, -28,  -2, -27,  -9;
/M: SY='K';  M=  11, -41, -21,  25, -42, -10, -26, -36,  58, -17, -29,  -1, -32,  10,  21, -22, -25, -13, -42, -33;
/M: SY='Q';  M=   7, -45,  18,  53, -50,  13, -22, -47,  13, -43, -34, -19, -30,  54,   7, -19, -27, -41, -44, -36;
/M: SY='K';  M=  36, -38, -28, -20, -29, -23,  14, -33,  52,  -8, -14,   1, -35,  -9,   3, -20, -24, -29, -34,  29;
/M: SY='M';  M= -28, -42, -36, -21, -26, -14, -22, -14, -23,  32,  73, -30, -39,  72, -23, -28, -29, -20, -39, -23;
/M: SY='D';  M=  14, -42,  46,  25, -48,  -8, -23, -46,  38, -44, -36,  -2, -31,  26,   9,   1, -23, -40, -47, -35;
/I:         I=-30; MD=-32;
/M: SY='E';  M=  21, -42,  44,  52, -49, -21, -25, -45,  -2, -43, -38,  -9, -30,  17, -17,   6,   1, -37, -51, -38; D=-30;
/I:         I=-30; MI=-32; IM=-32; DM=-32;
/M: SY='T';  M= -12, -31, -12, -25, -37, -22,  -8, -31, -21, -34, -30, -13, -28, -23,   2,  39,  77, -23, -53, -32;
/M: SY='G';  M= -19, -43, -27, -35, -48,  79,  19, -55,  10, -51, -39,  14, -35, -27, -21, -17, -32, -50, -43, -39;
/M: SY='M';  M= -23, -37, -42, -11,  -8, -48, -38,  35,  -6,  24,  42, -38, -24, -32, -21, -32,   5,  42, -44, -24;
/M: SY='K';  M= -28, -43, -25, -13, -42, -12, -28, -15,  77, -38, -29, -18, -32,  -5,  23, -23,  -1,  -7, -41, -32;
/M: SY='L';  M= -10,  -4, -49, -42, -14, -49, -41,   4, -42,  55,  -2, -47,  -9, -39, -42, -37, -25,  45, -44, -25;
/M: SY='L';  M= -34, -41,  -9, -34, -17, -46, -35,  -8, -39,  60,  -5, -44,  60, -36, -41, -39, -29, -15, -41, -27;
/M: SY='W';  M= -37, -56, -62, -45, -11, -13, -49, -27, -37, -22,  68, -52, -43, -34, -39, -44, -45, -37, 150,   0;
/M: SY='G';  M=  14, -37,   1, -33, -42,  59, -31, -30, -30, -39, -32,  45, -37, -29, -37, -10, -24,  15, -48, -39;
/M: SY='T';  M= -20, -29,   1, -26, -35, -35, -34, -26, -24, -31, -27, -13, -26, -28, -33,  -3,  92, -18, -56, -33;
/M: SY='A';  M=  61,   3, -29,  -5, -41,  -7, -35, -32, -27, -34, -29, -23, -31, -25, -33,  12,  40, -16, -46, -37;
/M: SY='N';  M= -28, -36,  -5, -22, -44, -18, -11, -43,  -8, -50, -36,  99,   1,   4, -23,   2, -14, -45, -60, -39;
/M: SY='L';  M= -20,  39, -47, -42, -13, -47, -34,  -2, -41,  60,  50, -13, -48, -36, -40, -38, -27,  11, -42, -23;
/M: SY='F';  M= -42, -39, -53, -49, 103, -49,  13, -17, -45,  -8, -18, -41, -52, -53, -41, -40, -34, -22,  -9,  14;
/M: SY='S';  M=  12, -30, -13, -25, -38,  -8, -30, -33, -19, -28, -10, -14, -30, -22, -30,  60,  54, -25, -50, -33;
/M: SY='H';  M= -20, -43,  22, -19, -40, -29, 104, -48, -22, -42, -28,  61,   2, -17, -22, -20, -25, -48, -66, -17;
/M: SY='P';  M= -17, -55, -32, -14, -51, -10, -34, -42, -16, -49, -37, -36, 105, -29,  11, -28, -27, -45, -45, -47;
/M: SY='R';  M= -18,  18, -35, -25, -37, -21, -26, -26,  -1, -31, -26, -27, -43, -15,  83, -28, -21,  24, -46, -31;
/M: SY='F';  M= -39, -42, -46, -45,  82, -45, -20, -20, -39, -14, -18, -40, -50, -40, -36, -13, -32, -25,  31,  80;
/M: SY='M';  M=  -1, -37, -38, -28, -27, -28, -28,  -7,  40,  -4,  84, -30, -37, -21,   3, -29, -24,  23, -43, -25;
/M: SY='H';  M=  24, -38,  57, -14, -45, -20,  59, -45, -23, -43, -35,  38, -35,  -8, -27,  21, -19, -39, -58, -29;
/I:         I=-30; MD=-32;
/M: SY='G';  M= -17, -45, -33, -44, -51,  89, -39, -59, -38, -55, -44, -18, -37, -36, -46, -18, -37, -53, -42, -46; D=-30;
/I:         I=-30; MI=-32; IM=-32; DM=-32;
/M: SY='A';  M=  69, -32, -34, -30, -44,  34, -36, -35, -29, -37, -30, -26, -34, -27, -13, -10, -22, -18, -42, -39;
/M: SY='F';  M=  55, -32, -38, -33,  58,  -5, -34, -28, -33, -25, -26, -29, -38, -32, -36,  20, -21, -22, -29, -14;
/M: SY='T';  M= -17, -28, -24, -27, -35, -32, -34, -27, -24, -32, -28, -13, -26, -27, -32,  24,  89, -19, -54, -32;
/M: SY='N';  M=  19, -31, -16, -24, -42, -17, -21, -39, -21, -44, -35,  63, -34, -18, -27,  60,   8, -33, -53, -36;
/M: SY='P';  M= -30,  36, -21, -24, -48, -28, -26, -42, -23, -49, -37,  60,  88, -26, -12,  -9, -21, -44, -53, -45;
/M: SY='D';  M= -32, -43,  84,   8, -10, -29,  -6, -47, -20, -47, -43,  49, -35, -20, -18,  -3, -21, -46, -58, -17;
/M: SY='P';  M=  32, -43, -35, -25,   9, -32, -32, -33, -19, -30, -29, -33,  73, -25,  39, -16, -25, -15, -40, -32;
/M: SY='D';  M= -17, -45,  74,  26, -45, -21,   1, -47,   8, -37, -41,  13, -17, -17, -24,   8, -23, -44,  46, -32;
/M: SY='V';  M= -16, -34, -49, -44, -21, -51, -52,  35, -41,  -6,  -9, -43, -44, -43, -44, -32,  -4,  77, -53, -28;
/M: SY='F';  M= -36, -42, -43, -36,  73, -47, -25, -20, -19, -11, -20, -36, -48, -30,  52, -35, -32,   5, -17,  44;
/M: SY='A';  M=  68, -32, -33, -26, -43,  -2, -33, -35, -20, -36, -29, -26, -34, -22,  31,   1,  -5, -24, -43, -37;
/M: SY='Y';  M= -37,   3, -41, -41,  44, -45, -13, -18, -32, -20,  -8, -38, -49, -31,  -7, -33,  -8, -27,  58,  98;
/M: SY='A';  M=  72,  -7, -33, -27, -42,  -1, -35, -33, -27, -35, -29, -27, -34, -25,  -6,  16, -18, -16, -44, -38;
/M: SY='A';  M=  59,  30, -39, -34,  -8,   8, -38,   2, -34,   6, -20, -32, -38, -31, -38, -11, -22,  -1, -42, -32;
/M: SY='A';  M=  58, -33, -32, -25, -41,  -5, -31, -33, -17, -35, -28, -25, -34,   2,  36,   3,  16, -12, -44, -35;
/M: SY='Q';  M= -27, -46, -22,  -6, -49, -35, -20, -42,  50, -39, -27, -16, -32,  84,  13, -17,  15, -40, -41, -30;
/M: SY='V';  M=  -5, -34, -44, -40, -22, -45, -46,  30, -38,   9, -10, -37, -41, -38, -41,  -3,  19,  64, -50, -28;
/M: SY='K';  M= -31,   2, -33, -21,   7, -43, -30,  14,  65,  13,  14, -25, -37, -18,  14, -30, -26, -17, -37, -24;
/M: SY='H';  M= -10, -42,  -2,   6, -42, -28,  56, -45,  45, -41, -31,  16, -33,  -3,  43,  -3,   9, -40, -48, -27;
/M: SY='C';  M=  41,  55, -26, -29, -42,  22, -29, -37, -27, -38, -13,  40, -37,   0, -33,  13,   4, -23, -49, -38;
/M: SY='M';  M= -32, -39, -52, -45, -13, -51, -35,  51, -42,  46,  73, -44, -44, -35, -41, -41, -28,   1, -40, -20;
/M: SY='D';  M= -31, -47,  83,  52, -53, -26, -19, -52, -16, -49, -45,  19, -30,  -4, -25, -22, -25, -48, -60, -38;
/M: SY='L';  M=  33, -34, -45, -39, -20, -38, -40,  32, -39,  38,   3, -40, -42, -35, -40, -18, -12,  27, -43, -27;
/M: SY='T';  M=  37,  -6, -29, -30, -40,  32, -35, -33, -28, -36, -30, -18, -30, -28, -35,   8,  63, -24, -48, -37;
/M: SY='K';  M=  23, -40, -29, -18, -37, -34,  48,   1,  54, -29, -23, -22, -34,  16,  -6, -22, -24,  15, -45, -27;
/M: SY='E';  M=  -3, -46, -12,  61, -42, -40, -21, -47,  30, -41, -34, -23, -30,  -1,  53, -23, -23, -40, -41,  -3;
/M: SY='L';  M= -33,  13, -49, -42, -10, -51,  13,  -1, -43,  68,  26, -46, -50, -36, -40, -42, -29,   4, -41, -20;
/M: SY='G';  M= -17, -43, -13, -38, -48,  84, -36, -49, -15, -49, -40,   2, -36, -32, -29, -17, -32, -21, -42, -43;
/M: SY='G';  M=  52, -35, -32, -34, -46,  64, -37, -44, -33, -43, -35, -22, -34, -30, -39,  -1, -26, -33, -42, -41;
/M: SY='E';  M=  -7, -45,  -4,  72, -46, -39, -22, -42,  25, -31, -14, -10, -27,  30,   6, -22, -15, -26, -45, -36;
/M: SY='N';  M=  -9, -34, -10, -27, -39,  -3, -18,  -6, -20, -39, -31,  87, -37, -22, -28, -11,  32, -15, -57, -37;
/M: SY='Y';  M= -37, -46, -38, -41,  37, -44,  -8, -22, -33,  -8, -16, -38, -49, -29, -31, -11, -31, -27,   2, 107;
/M: SY='V';  M= -19, -33, -48, -43, -21, -50, -52,  13, -41,  -7, -10, -43, -45, -44, -43, -31,   2,  82, -55, -29;
/M: SY='F';  M=  -6,  20, -51, -45,  73, -46, -35,  -8, -43,  38,  26, -44, -49, -44, -41, -37, -30,   3, -23,  -3;
/I:         I=-30; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='W';  M= -43, -68, -70, -47,  -7, -41, -70, -40, -39, -38, -41, -63, -46, -39, -43, -49, -55, -55, 166,   6;
/M: SY='G';  M= -17, -44, -31, -41, -50,  88, -38, -57, -36, -53, -42, -18,   9, -34, -44, -17, -35, -51, -41, -45;
/M: SY='G';  M= -16, -44, -31, -43, -50,  90, -38, -58, -37, -53, -42, -17, -35, -34, -44, -16, -35, -51, -41, -45;
/M: SY='R';  M= -34, -50, -30, -18, -43, -44, -19, -50,  10, -42, -31, -23, -42,  -7,  99, -28, -33, -43, -43, -29;
/M: SY='E';  M= -27, -48,   2,  93, -50, -43, -20, -52,  -8, -43, -40, -24, -22,  -1, -18, -24, -27, -44, -47, -40;
/M: SY='G';  M= -16, -44, -31, -43, -50,  90, -38, -58, -37, -53, -42, -17, -35, -34, -44, -16, -35, -51, -41, -45;
/M: SY='Y';  M=  28, -42, -36, -36,   4, -35, -11, -24, -32, -23, -19, -35, -45, -27, -31, -10, -27, -11,  -4,  99;
/M: SY='E';  M= -22, -47,  21,  84, -47, -41,   3, -45, -11, -38,  18, -22, -25,  17, -19, -24, -27, -40, -48, -36;
/M: SY='T';  M= -17, -10, -24, -28, -28, -27, -26, -27, -25, -33, -29,  14, -32, -23, -31,  52,  60,  -4, -42,  27;
/M: SY='L';  M= -31, -39,  25,  -3, -17,   9, -32,  -4, -37,  59,  -6, -34, -44, -32, -39, -35, -30, -15, -42, -26;
/M: SY='L';  M=  16, -36, -44, -39, -16,   3, -16, -11, -39,  56,  -6, -39, -44, -33, -39,  -2, -27, -15,  49, -12;
/M: SY='N';  M=  26, -32, -10, -25, -42, -18, -16, -38, -19, -35, -33,  89, -37, -19, -26,   1,   7, -35, -56, -38;
/M: SY='T';  M= -21, -32, -24, -22, -38,  -6, -32, -31,  39, -35, -29, -14, -27, -22, -18,  -8,  79, -24, -50, -33;
/M: SY='D';  M= -33, -46,  92,  12, -53, -30, -19, -51,   2, -50, -46,  28, -34,  -1, -25, -21, -23, -48, -65, -37;
/M: SY='M';  M=  -6, -36, -47, -38, -18, -44, -32,  10, -36,  36,  79, -40,  -6, -15, -24, -25, -20,  28, -43, -23;
/M: SY='K';  M=   4, -43, -25,  -4, -45,  16, -24, -46,  53, -43, -22,  -4, -34,  12,  51,  -3, -26, -40, -42, -33;
/M: SY='R';  M=  -4, -44,  17,  -4,   2, -21, -25, -21,   9,  11, -22, -24, -40,  21,  60, -27, -29, -21, -41, -26;
/M: SY='E';  M=  26, -42,  -7,  78, -46, -15, -25, -39, -14, -38, -35, -26, -26,  -8, -23, -20, -25, -10, -46, -39;
/M: SY='L';  M= -27, -42, -26, -17, -20, -45, -29, -15,   4,  49,   8, -35, -43,  39,  25, -33, -22, -20,  48, -22;
/M: SY='D';  M=  -6, -46,  79,  52, -52, -34, -21, -50,   3, -47, -43, -10, -30,   3, -23, -22, -25, -45, -57, -38;
/M: SY='H';  M= -32, -47, -21, -16, -39, -34,  76, -45,  -9, -32, -27,  42, -39,  54,  48, -22, -29, -46,  47, -19;
/M: SY='M';  M=  -5, -37, -48, -42,  15, -45, -28,  19, -38,  39,  75, -42, -44, -33, -37, -36, -27,   7, -30,  31;
/M: SY='A';  M=  48, -37, -31, -26, -45,  39, -31, -42,  18, -41, -32, -23, -35, -21,  37, -11, -26, -32, -42, -37;
/M: SY='R';  M= -29, -47, -16,  50, -45, -40, -20, -47,  24, -41, -15,  -9, -33,   4,  70,  -6, -18, -41, -44, -33;
/M: SY='F';  M=  23, -36, -47, -41,  79, -17, -34, -16, -39,   0,  39, -39,  -9, -41, -39, -30, -29,  -6, -21,  -1;
/M: SY='F';  M= -34, -37, -52, -45,  62, -50, -33,   7, -43,  47,  44, -46, -49, -41, -41, -41, -30,  10, -25,  13;
/M: SY='H';  M= -22, -42,  34,   0, -44, -30,  63, -45,  15, -42, -32,  44, -34,  39,   0,   7,  10, -42, -55, -27;
/M: SY='M';  M= -15, -36, -49, -41,  23, -45, -28,   2, -37,  40,  95, -40, -42, -31, -36, -37,  -9,  -9, -36, -15;
/M: SY='A';  M=  44,   7, -44, -36, -24, -34, -40,  -4, -37,  25,  22, -39, -41, -34, -39, -24, -21,  43, -45, -29;
/M: SY='V';  M=  16,  13, -40, -35, -30,  18, -17,  12,   2, -20, -19, -32, -41, -32,   8, -25, -23,  53, -48, -32;
/M: SY='D';  M=  11, -44,  68,  53, -35, -13, -22, -48, -17, -45, -41,  -3, -30,   7, -17, -13, -25, -41, -53, -37;
/M: SY='Y';  M= -38, -49, -34, -36,   9, -44,  62, -27, -31, -22, -17, -32, -48, -25, -27, -32, -33, -32,   0, 107;
/M: SY='K';  M=  40, -35, -32, -23, -38,   4, -35,  -8,  48, -30, -25, -25, -34, -21, -16,  -4, -21,  23, -43, -34;
/M: SY='H';  M= -30, -43,  -1,  26, -35, -37,  68, -43,  37, -38, -29,  11, -32,  -5,  24, -20,  26, -39, -45,  13;
/M: SY='K';  M=  -5, -43,  42,  42, -48, -23, -23, -47,  50, -45, -37, -15, -30, -10,  17,   8, -23, -41, -47, -35;
/M: SY='I';  M= -30, -46, -37, -28, -26, -47, -35,  69,   1, -11, -10,  -8, -38,  51,   2, -30, -21,   0, -41, -26;
/M: SY='G';  M= -17, -44, -14, -30, -50,  88, -37, -57, -35, -53, -42,  -7, -35, -33, -43, -16, -34, -51, -41, -44;
/M: SY='F';  M= -41, -42, -46, -45,  85, -47,  16, -19, -39,  -9, -17, -40, -51, -41, -36, -37, -34, -24,  -3,  79;
/M: SY='D';  M= -23, -42,  53,  13, -46,   8,  -9, -44,  40, -36, -37,  25, -32,   2, -15,  -8,  18, -40, -51, -35;
/M: SY='G';  M=   3, -41, -36, -40, -29,  66, -35, -11, -37,  15, -23, -26,  -3, -34, -42, -22, -19, -22, -36,   9;
/M: SY='Q';  M=  -4, -41,  -5, -14, -43, -35, -23, -27,  14, -31, -27,  -2,  -8,  59,  43, -12,  39, -24, -45, -31;
/M: SY='F';  M= -38, -39, -54, -49,  84, -52, -37,  34, -45,  25,  12, -45, -49, -48, -43, -41, -31,  -8, -18,   3;
/M: SY='L';  M=  36, -34, -45, -38,   2, -37, -34,  -8, -39,  57,   7, -42, -45, -34, -39, -29, -26, -11, -37,  -8;
/M: SY='I';  M= -32, -43, -53, -50, -14, -57, -49,  80, -46,  28,  -1, -44, -43, -42, -48, -41, -26,  16, -40, -23;
/M: SY='E';  M= -54, -96,   4, 187,-101, -86, -40,-103, -16, -87, -80, -47, -44,  -1, -36, -47, -55, -87, -94, -81;
/M: SY='P';  M= -33, -59, -34, -22, -53, -35, -37, -41, -30, -51, -37, -40, 114, -33, -42, -30, -26, -46, -46, -50;
/M: SY='K';  M= -29, -44, -22,  -8, -46, -37, -25, -46,  90, -45, -33, -15, -30,  -6,  10, -24, -24, -42, -39, -32;
/M: SY='P';  M= -26, -58, -34, -22, -53, -35, -37, -41, -30, -51, -37, -40, 114, -33, -42, -30, -26, -45, -46, -50;
/M: SY='N';  M= -16, -41, -16, -13, -44, -29,  13, -40,  48, -39,  18,  60, -34,  56,  -7, -18, -22, -40, -46, -31;
/M: SY='E';  M= -27, -48,   2,  93, -50, -43, -20, -52,  -8, -43, -40, -24, -22,  -1, -18, -24, -27, -44, -47, -40;
/M: SY='P';  M= -33, -59, -34, -22, -53, -35, -37, -41, -30, -51, -37, -40, 114, -33, -42, -30, -26, -46, -46, -50;
/M: SY='T';  M= -22, -35, -27, -24, -37, -36, -28, -32, -11, -32,   7, -17, -31, -19,  53,  16,  71, -25, -50, -31;
/M: SY='K';  M= -23, -42, -26, -20, -44,  45, -29, -45,  64, -37, -16, -16, -32, -16,   2,  -8,  11, -40, -41, -35;
/M: SY='H';  M= -36, -48,  57, -12, -26, -36, 114, -52, -24, -39, -28,  -7, -36, -17, -22, -25, -31, -51, -68, -11;
/M: SY='Q';  M= -28, -49, -29, -11, -39, -40, -23,  43, -15, -21, -16, -23, -36,  95, -16, -22, -28, -17, -39, -26;
/M: SY='Y';  M= -38, -46, -40, -41,  21, -46,  -9, -17, -35,  20, -12, -41, -51, -30, -32, -35, -32, -23,   0, 105;
/M: SY='D';  M= -35, -44,  87,  -8,   3, -37, -24, -30, -28,  23, -27, -12, -39, -26, -34, -28, -26, -32, -54, -27;
/M: SY='F';  M=   3, -43, -41, -36,  62, -39, -27, -23, -35, -22, -23, -38,  52, -37, -38, -23,  -7, -13,  37,  59;
/M: SY='D';  M= -29, -41,  87,  -5, -47, -32, -24, -42, -22, -44, -42,  -5, -31, -23, -31, -15,  50, -37, -65, -36;
/M: SY='V';  M=  39, -31, -40, -35, -28, -33, -42,   1, -35,  -9, -17, -33, -39, -34, -38,   6,  15,  57, -50, -32;
/M: SY='A';  M=  57, -35, -28,   7, -46,  48, -34, -41, -28, -40, -33, -23, -33,   2, -34,  -3, -24, -30, -42, -40;
/M: SY='T';  M= -17, -33, -23, -25, -35, -34,  75, -32, -24, -32, -26,  -8, -29, -23, -28,  11,  77, -25, -58, -23;
/M: SY='V';  M=  40,  19, -39, -35, -31,  -2, -41,  -7, -34, -19,  19, -32, -38, -34, -38, -14,  19,  49, -49, -33;
/M: SY='Y';  M= -26, -41, -47, -44,  19, -50,   9,  43, -40,  39,  23, -42, -46, -35, -39, -38, -29,  -5, -22,  58;
/M: SY='A';  M=  56, -34, -30, -24, -43,  52, -34, -41, -30, -41, -33,   2, -34, -27, -36,   6, -23, -30, -41, -21;
/M: SY='F';  M= -42, -38, -55, -50, 104, -50, -35, -15, -46,   3, -16, -44, -53, -55, -43, -41, -34, -20,  -8,  13;
/M: SY='L';  M= -33, -38, -52, -46, -10, -54, -40,  48, -45,  60,  19, -48, -47, -39, -44, -43, -28,  10, -39, -21;
/M: SY='K';  M= -22, -45, -10,  34, -45, -37,  24, -43,  50, -30, -30,   1, -32,  42,  38, -17, -19, -31, -44, -30;
/M: SY='Q';  M=  -9, -42, -15,  20, -44, -27,  14, -41,  31, -39, -30,  -4, -32,  44,  42, -12,  34, -36, -45, -31;
/M: SY='Y';  M= -37, -42, -40, -39,  45, -46,  52, -16, -37,  35,  -9, -22, -49, -32, -33, -36, -32, -21, -14,  76;
/M: SY='G';  M= -22, -45,  39,  41, -51,  64, -28, -55, -24, -50, -43,   7, -31, -20, -33, -19, -30, -49, -47, -42;
/M: SY='L';  M= -34, -40, -43, -34, -15, -50,  28,  -9, -23,  61,  -3, -39, -48, -26,  43, -38, -31, -15, -41, -21;
/M: SY='P';  M= -30, -49,  45,  47, -29, -16, -26, -30, -12, -27, -17,  -9,  63,   7, -28, -24,  -9, -40, -49, -38;
/M: SY='E';  M= -28, -44,  46,  47, -49, -11,   2, -49,  42, -46, -38,  28, -30,   7, -12,  -8, -17, -44, -50, -36;
/M: SY='E';  M= -31, -44,  42,  47, -28, -41,  34, -12, -20,  15,   7, -22, -35, -16,   3, -18, -20, -16, -44,  12;
/M: SY='F';  M= -34, -39, -51, -47,  80, -50, -35,  21, -43,  -7, -13, -43, -49, -47, -42, -38, -28,  36, -16,  41;
/M: SY='K';  M= -18, -44, -25, -17, -47,  45, -28, -49,  72, -47, -35, -16, -32,  -5,   5, -21, -27, -44, -40, -36;
/M: SY='L';  M= -28, -36, -51, -44,  15, -52, -41,  21, -44,  51,  16, -47, -48, -41, -43, -39, -25,  47, -40, -20;
/M: SY='N';  M= -29, -34,  -2, -24, -44, -17, -10, -43, -15, -51, -37, 105, -40, -17, -23, -11, -13, -45, -63, -39;
/M: SY='P';  M= -32, -46, -46, -39, -23, -48, -44,  60, -40,  21,  -9, -43,  66, -39, -46, -37, -26,   9, -42, -30;
/M: SY='E';  M= -54, -96,   4, 187,-101, -86, -40,-103, -16, -87, -80, -47, -44,  -1, -36, -47, -55, -87, -94, -81;
/M: SY='A';  M=  41,  14, -36, -28,   2,   2, -36, -16, -29, -25, -23, -29, -14,  29, -33, -16,  19,  32, -44, -30;
/M: SY='N';  M=   5, -36, -12, -29, -46,  48, -19, -46, -22, -50, -38,  83, -38, -22, -30, -12, -20, -44, -53, -41;
/M: SY='H';  M= -73, -96, -40, -40, -69, -76, 261,-106, -50, -70, -41, -19, -74, -28, -38, -51, -70,-105,-141,  -7;
/M: SY='A';  M=  65, -33, -19,  48, -45, -23, -31, -37, -22, -37, -31, -27, -29, -16, -28, -12, -10, -25, -44, -39;
/M: SY='T';  M= -23, -35, -25, -22, -34, -36, -29,  12, -21, -24, -23,  11, -30,  50, -26, -10,  72, -18,   2, -14;
/M: SY='M';  M= -32, -36, -51, -42, -10, -49, -30,   0, -41,  63,  78, -46, -46, -33, -38, -42, -29,  -7, -39, -19;
/M: SY='A';  M=  76, -28, -33, -27, -42, -16, -35, -32, -29, -34, -28, -27, -33, -25, -33,  18, -17, -14, -43, -38;
/M: SY='G';  M= -17, -43, -29, -40, -39,  87, -35, -56, -34, -52, -41,  10, -35, -16, -42, -16, -33, -50, -41, -43;
/M: SY='H';  M= -36, -44, -28, -26, -24, -42, 115, -28, -30,  32, -11, -19, -41, -20, -25, -31, -33, -32, -57,  -8;
/M: SY='N';  M= -18, -31, -11, -20, -39, -23, -23, -35, -21, -40, -33,  61, -31, -20, -28,  45,  59, -29, -56, -35;
/M: SY='F';  M= -41,  12, -53, -49,  99, -49, -30, -17, -44,  -9,   5, -43, -52, -51, -41, -40, -34, -22,  -8,  41;
/M: SY='E';  M= -20, -45,  -6,  53, -43, -39,  45, -35, -16, -21, -14, -22,  32,  47, -22, -21,  14, -10, -48, -30;
/M: SY='H';  M= -21, -47, -20, -19, -36, -37, 128, -52, -24, -35, -21, -10, -37,   7, -19, -25, -34, -51, -68,  -5;
/M: SY='E';  M=  -4, -46,   8,  76, -50,  37, -25, -52, -15, -45, -40, -21, -26,  -9, -25, -20, -29, -44, -46, -41;
/M: SY='I';  M= -30, -39, -52, -47, -13, -54, -44,  59, -45,  46,  10, -46, -45, -40, -45, -41, -26,  31, -41, -23;
/M: SY='A';  M=  59, -34, -20,  -6, -42, -24,  -3, -34, -16, -34,   0,   5, -35,   7,  37, -14, -14, -16, -45, -34;
/M: SY='Q';  M= -18, -38, -32, -22, -26, -40, -27, -11, -23,   7,  14, -18, -37,  63, -25, -20,  34,  33, -40,  14;
/M: SY='A';  M=  81, -28, -35, -27, -43, -16, -36, -32, -29, -34, -28, -29, -33, -26, -34,  -8, -19, -19, -43, -38;
/M: SY='R';  M=   4, -15, -37, -20, -16, -32, -29,  -7, -10,  28, -16, -19, -42, -11,  56, -12, -16,  -2,  31, -17;
/M: SY='W';  M=  13, -43,  41,   6, -28, -32, -33,  12, -16, -21, -29,   0, -36, -25, -32,   5,   3, -21,  96,   0;
/M: SY='A';  M=  42, -35, -30, -20,  -8, -29,  38, -22, -29,  25, -16,  25, -39,   7, -31, -14, -23, -13, -41,   3;
/M: SY='G';  M= -19, -43,   1, -14, -49,  80, -19, -55, -12, -52, -41,  22, -35, -28, -36, -16, -31, -50, -44, -43;
/M: SY='M';  M=  -8, -39, -38, -28, -16, -33, -32,  30,  47,  13,  56, -30, -37, -23, -16, -31, -25,  13, -40, -25;
/M: SY='L';  M= -36, -36, -52, -45,  47, -52, -35,  -2, -45,  67,   1, -49, -52, -41, -42, -44, -31,  -9, -30, -11;
/M: SY='G';  M= -23, -12, -37, -45,  53,  74, -37, -39, -39, -20, -31, -24, -40, -40, -44, -23, -35, -38, -29, -18;
/M: SY='H';  M= -16, -36, -21, -22, -39, -22,  83, -44, -24, -41, -32,   7, -33, -15, -25,  71, -11, -39, -55, -22;
/M: SY='I';  M= -30, -43, -53, -50, -15, -56, -51,  80, -45,  17,  -2, -44, -42, -42, -48, -40, -25,  30, -42, -24;
/M: SY='D';  M= -69, -96, 205,   4,-110, -62, -40,-106, -44,-103,-101,  -4, -68, -42, -61, -45, -48,-100,-141, -75;
/M: SY='A';  M=  57, -31, -41, -33, -25, -28, -34, -14, -34,  34,  43, -36, -39, -29, -36, -20, -23,  -8, -41, -29;
/M: SY='N';  M= -29, -34,  -2, -24, -44, -17, -10, -43, -15, -51, -37, 105, -40, -17, -23, -11, -13, -45, -63, -39;
/I:         I=-30; MD=-32;
/M: SY='R';  M= -45, -63, -43, -29, -61, -56, -35, -57, -16, -52, -12, -36, -53,  52,  57, -36,  -1, -54, -59, -45; D=-30;
/I:         I=-30; MI=-32; IM=-32; DM=-32;
/M: SY='G';  M= -18, -43,   6, -36, -49,  83, -33, -56, -32, -53, -42,  26, -36, -31, -33, -16, -32, -50, -44, -43;
/M: SY='D';  M= -31, -48,  82,   0, -54, -31,   8, -49, -16, -46, -39,  10, -34,  64, -21, -10, -25, -48, -57, -33;
/M: SY='Y';  M=  -7, -43, -20, -26, -21, -36,  22, -27,   6,  -6,  -3, -19,  48, -23,  22,  11, -13,  -5, -31,  48;
/M: SY='Q';  M= -26, -43, -16, -21, -31,  31, -26,  -7, -24,  31,  21, -26, -39,  70, -25, -24, -30, -25, -40, -28;
/M: SY='I';  M= -27, -38, -32, -37, -21, -16, -32,  40, -34,  36, -10,  38,  -5, -30, -38,  15, -12,  -3, -45, -28;
/M: SY='G';  M= -14, -44, -29, -30, -48,  74, -33, -54,  34, -50, -39, -17, -34, -23,  16, -19, -32, -47, -40, -40;
/M: SY='W';  M= -42, -60, -59, -46,  29, -42, -42, -33, -38, -30, -32, -55, -48, -38, -39, -45, -47, -44, 151,  60;
/M: SY='D';  M= -69, -96, 205,   4,-110, -62, -40,-106, -44,-103,-101,  -4, -68, -42, -61, -45, -48,-100,-141, -75;
/M: SY='T';  M= -22, -35, -25, -18, -38, -36, -27,  -7, -19, -29,   0, -16, -29,  63, -23,  -8,  75, -21, -48, -30;
/M: SY='D';  M= -69, -96, 205,   4,-110, -62, -40,-106, -44,-103,-101,  -4, -68, -42, -61, -45, -48,-100,-141, -75;
/I:         I=-30; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='Q';  M= -27,   7, -18,  41, -47, -40, -20, -34,  -7, -35, -27, -22, -34,  80,  37, -21, -28,   1, -44, -31;
/I:         I=-30; MD=-32;
/M: SY='F';  M= -42, -39, -55, -51, 103, -24, -35, -17, -46,  -9, -19, -43, -53, -56, -43, -41, -35, -22,  -9,  13; D=-30;
/I:         I=-30; MI=-32; IM=-32; DM=-32;
/M: SY='P';  M= -13, -50, -33, -28, -48,  41, -36, -42, -32, -30, -36, -31,  94, -32, -42,  -5, -27, -43, -44, -46;
/M: SY='N';  M=   8, -34, -20, -26, -35, -27,  41, -21, -21, -32,  21,  53, -20, -21,  -8,  16,  47, -27, -52, -14;
/M: SY='D';  M= -24, -40,  56,   5, -46,  29, -21, -43, -20, -38, -39,  52, -35, -20,  -5,  18, -20, -23, -55, -38;
/M: SY='V';  M= -18, -38,  36, -28, -25, -41, -19,  30, -31,  11, -15,  23, -42, -32, -13, -29, -15,  43, -51, -17;
/M: SY='Y';  M= -33, -45, -30,  18,  -1, -30, -21, -14, -16,  29, -15, -11,  39, -25, -11, -22, -28, -25, -22,  63;
/M: SY='E';  M=  -6, -43,  25,  64, -44, -37, -23, -41,  16, -19, -14,  -6, -28,   7,  12,  -6,   5, -36, -47, -35;
/M: SY='T';  M=  36,   2, -23, -31, -30, -11, -31,  -8, -29,   5,  19,  25, -35, -28, -34,  -2,  40,  -1, -47, -19;
/M: SY='T';  M=  49, -29, -30, -29, -37, -10, -36, -24, -28, -29,  -5, -22, -31, -28, -34,   4,  61,   3, -48, -34;
/M: SY='F';  M= -15, -37, -45, -18,  61, -36, -33,  -8, -39,  47,  15, -41, -47,  -1, -38, -36, -12,  -3, -27,  -8;
/M: SY='W';  M=  48,  11, -42, -35,  19, -29, -40,   0, -35,  -3,  -5, -35, -39, -33, -38,   3,  -9,  19,  63, -21;
/M: SY='M';  M= -30, -37, -47, -41,   6, -45, -25,   1, -36,  34,  92, -39, -42, -30, -35, -36,   1,  -1,   7,  32;
/M: SY='Y';  M= -30, -42, -42, -40,  -1, -46,   9,  -6, -22,   3,  20, -40, -47, -32, -33, -23, -27,  40,  42,  83;
/M: SY='E';  M= -19, -46,  55,  63, -44, -37,  12, -41, -14, -39, -20, -17, -29,  15,  -4,  -8, -25, -12, -50, -10;
/M: SY='I';  M= -29, -39, -52, -47,  11, -54, -45,  57, -44,  37,   8, -46, -45, -42, -45, -40, -25,  40, -40, -20;
/M: SY='L';  M= -33, -37, -52, -44,  -4, -53, -38,  27, -45,  68,   3, -49, -50, -39, -43, -43, -29,   9, -39, -20;
/M: SY='E';  M= -19, -46,  -6,  60, -45, -39, -22, -45,  49, -23, -32, -11, -29,  24,  29, -23, -27, -40, -43, -34;
/M: SY='N';  M=  33, -34, -17, -16, -30,  -4,  18, -39, -19, -41, -13,  66, -36,   3,   4,  22, -12, -34, -50, -33;
/M: SY='G';  M=  13, -40,   4, -35, -47,  77, -35, -47, -34, -47, -39,  -8, -35, -31, -40,   4, -29, -23, -43, -42;
/I:         I=-30; MD=-32;
/M: SY='G';  M= -18, -45, -32, -41, -51,  84, -38, -57, -36, -54, -43, -19,  -3,  -9, -43,  -7, -35, -51, -43, -45; D=-30;
/I:         I=-30; MI=-32; IM=-32; DM=-32;
/M: SY='F';  M= -37, -41, -15, -43,  68, -49, -27,  21, -41,  29, -10, -42, -49, -41, -40, -39, -31,  -3, -15,  57;
/I:         I=-20; MD=-21;
/M: SY='T';  M=   9, -47, -11, -28, -55,  34, -44, -50, -15, -51, -44, -29,  -7,  -9, -42, -22,  39, -42, -58, -49; D=-20;
/I:         I=-20; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='T';  M=  -8, -40,  21,   6, -44, -14,   3, -38,   8, -40, -32,   9,  33,  24,   0,   2,  48, -33, -50, -34;
/M: SY='G';  M= -16, -11, -31, -43, -50,  89, -38, -58, -37, -53, -42, -17, -35, -34, -44, -16, -35, -51, -41, -45;
/M: SY='G';  M= -20, -47, -32, -35, -50,  75, -37, -52, -34, -52, -41, -22,  62, -33, -43,  -5, -31, -49, -42, -46;
/M: SY='R';  M= -31, -39, -39, -32,  28, -46, -29,   2, -17,  31,   3, -19, -43, -26,  52, -29,  22,  -3, -36,  -8;
/M: SY='N';  M= -31, -38,  -7, -23, -40, -23,  84, -45, -18, -44, -16,  90, -39, -16, -22, -15, -19, -47, -65, -24;
/M: SY='F';  M= -43, -38, -55, -50, 105, -50, -35, -16, -46,  -7, -18, -44, -53, -57, -43, -41, -34, -21,  -7,  14;
/M: SY='D';  M= -70, -96, 203,   3,-104, -63, -39,-105, -44,-101, -99,  -5, -68, -42, -61, -45, -49, -99,-133, -33;
/M: SY='A';  M=  66,   2, -36, -30,  25, -22, -31, -29, -31, -29, -26, -30, -37, -29, -34,   5, -10, -21, -30,  28;
/M: SY='K';  M= -30, -44, -22,  -9, -44, -37,  42, -47,  86, -44, -31, -14, -30,  -7,   7, -24, -25, -43, -41, -28;
/M: SY='P';  M=   8, -40, -41, -33, -29, -40, -41,   5, -34,  14, -16, -40,  66, -36, -27, -28,   0,  42, -47, -34;
/M: SY='R';  M= -31, -48, -31, -21, -37, -40, -22, -42,   1, -16, -28, -25,  30, -12,  84,   9, -27, -39, -40,  -1;
/M: SY='R';  M= -34, -50, -30, -18, -43, -44, -19, -50,  10, -42, -31, -23, -42,  -7,  99, -28, -33, -43, -43, -29;
/M: SY='T';  M=  -4, -37, -20,  12, -43,  -1, -25, -35, -17, -37, -29,  14, -10,  59, -23,   0,  59, -30, -48, -33;
/M: SY='S';  M= -13, -35,   3,  45, -44, -23, -24, -44, -19, -44, -39, -14, -28, -11, -25,  73,  -9, -36, -49, -35;
/I:         I=-30; MD=-32;
/M: SY='F';  M= -47, -53, -60, -58,  50, -62, -53,   9, -55,   1, -15, -51, -58, -57, -56, -29,  20, -18,   2, -12; D=-30;
/I:         I=-30; MI=-32; IM=-32; DM=-32;
/M: SY='D';  M= -15, -44,  84,  26, -49, -13, -21, -48,  -3, -47, -43,  15, -32,  -8, -26, -20,   3, -44, -59, -23;
/M: SY='P';  M=  13, -43, -25,   7,  25, -38, -29,   4, -25,  -3,  17, -36,  57,  -8, -29, -23, -26,  -5, -30,  31;
/M: SY='E';  M=  -8, -45,  52,  68, -44, -37, -21, -28, -14, -41, -37,  -2, -28,  10, -23, -21,   1, -38, -48,  -6;
/M: SY='D';  M= -11, -46,  87,  -7, -53,  40, -25, -53, -26, -51, -47,  -6, -34, -24, -34, -20, -27, -48, -59, -39;
/M: SY='L';  M= -28, -36, -50, -44, -13, -52, -41,  25, -43,  55,  17, -47, -47, -39, -42, -39, -16,  45, -43, -23;
/M: SY='W';  M= -39, -45, -56, -46,  75, -48, -44,  16, -19,   6, -18, -47, -48, -45, -40, -42, -36, -10, 112,   5;
/M: SY='H';  M=  18, -41,   4,  -9, -13, -38,  55,  23, -30,   8,  -5, -28,   1, -26, -14, -26,  -8, -17, -34,  42;
/M: SY='A';  M=  47, -32, -31, -30,  14,  30, -33, -36, -30, -36, -32, -21, -34, -26, -34,  46,  -9, -28, -39, -29;
/M: SY='H';  M=  36, -41, -24, -22, -35, -30, 114, -45, -26, -35, -23, -15, -36, -18, -23, -19, -29, -39, -57,   0;
/M: SY='I';  M=   7, -41, -41, -16, -24, -46, -42,  66,   1, -10, -11, -35, -39, -30,  12, -31, -15,  26, -43, -27;
/M: SY='G';  M=  45, -36, -32, -35, -45,  67, -37, -41, -33, -42, -35, -22, -34, -30, -39,   4, -26, -19, -42, -41;
/M: SY='C';  M=  17,  76, -30, -38, -45,  64, -35, -48, -34, -45, -38,  23, -39, -33, -40,  -5, -27, -40, -48, -44;
/M: SY='M';  M= -28, -37, -51, -41, -17, -44, -24,  24, -34,   4, 117, -38, -38, -26, -33, -38, -26,  -1, -41, -17;
/M: SY='D';  M= -33, -48,  87,  -3, -51, -34, -20, -52, -11, -48, -44,  -7, -36, -16,  49,  -9, -25, -47, -60, -35;
/M: SY='T';  M=  24,  -3, -27, -29, -33, -29, -16,  -6, -26, -25,  34,  29, -33, -27, -32,   9,  58,   3, -51, -32;
/M: SY='Y';  M= -36,  54, -46, -44,  57, -47, -20,  -9, -38,   8,  35, -40, -50, -37, -37, -36, -31, -14, -10,  78;
/M: SY='A';  M=  66, -30, -39, -31, -28, -24, -36, -19, -34,  32, -15, -35, -38, -29, -36, -16, -22, -15, -41, -32;
/M: SY='R';  M=   1, -42, -40, -31, -24, -45,  -8,  38,  -3,  29, -11, -34, -42,  -5,  50, -32, -28,  -2, -41, -25;
/M: SY='G';  M=  23, -37, -37, -38, -30,  58, -36, -26, -37,  30, -19, -27, -39, -32, -40,   3, -27, -26, -41, -34;
/M: SY='L';  M= -25, -38, -39, -29,  20, -46, -32, -11,  44,  53,  -7, -35, -43, -26,  -8, -35, -28, -14, -35, -19;
/M: SY='E';  M= -30, -46,   9,  50, -41, -41, -23, -20,  49, -14, -12, -21, -31,   9,  36, -26, -27, -26, -44, -33;
/M: SY='R';  M=  19,  -2, -33, -27, -35, -26, -30,   1,   8, -21, -23,   3,  -7, -21,  54,  -5, -23,  26, -46, -32;
/M: SY='A';  M=  79, -29, -35, -27, -42, -17, -36, -31, -28, -33, -28, -29, -34, -25, -11,  -9, -19, -12, -43, -38;
/M: SY='A';  M=  51, -35,  -2,   2, -34, -27,  12, -26,  -7,  -8, -11, -11,  -5,   7,  -7, -13, -22,   2, -42,   2;
/M: SY='A';  M=  45, -37,  -8, -18, -43, -28, -28, -37,  44, -34, -30,  -3,  -4,  -4,  34, -17, -11, -20, -43, -35;
/M: SY='M';  M= -33, -37, -51, -44,  57, -47, -31,  21, -41,  37,  74, -42, -45, -37, -39, -20, -28,  -9, -28,  -7;
/M: SY='R';  M= -17, -42, -12, -31, -24, -46, -12,  42,   2,  21,  -2, -22, -42, -25,  47, -32, -19,  11, -42, -17;
/M: SY='E';  M=  25, -42,  10,  68, -48, -13, -24, -43,  -4, -41, -36,  -1,  -1,  12, -22, -12, -17, -29, -47, -39;
/I:         I=-28; MD=-29;
/M: SY='D';  M= -20, -46,  90,  18, -53, -21, -21, -51, -13, -50, -47,  21, -34, -20, -29, -15,  -7, -47, -65, -38; D=-28;
/I:         I=-28; MI=-29; MD=-29; IM=-29; DM=-29;
/M: SY='P';  M= -11, -47,   6, -17, -49,  44,  -3, -48,   3, -49, -38,  -5,  57, -17,  22,   6, -27, -45, -46, -40; D=-28;
/I:         I=-28; DM=-29;
/M: SY='E';  M=  -1, -41, -11,  43,  23, -28, -27, -28,  21, -30, -28, -25,  -5,  20,  11,  -5,  -9,  10, -39, -25;
/M: SY='L';  M= -30,  11, -51, -45,  29, -52, -39,  23, -43,  48,  11, -46, -49, -41, -42, -39, -26,  39, -35,   6;
/M: SY='Q';  M= -10, -45,  43,  39, -50, -26, -20, -46,  11, -43, -35, -11, -14,  62,   6,  13, -15, -42, -47, -34;
/M: SY='E';  M=   7, -43,  17,  49, -48,   2, -22, -46,  26, -44, -35,  19, -14,  27,   8,  -6, -16, -40, -46, -37;
/M: SY='L';  M=  26, -37, -44, -37,  25, -39, -35,  15, -33,  29,  26, -28,   9, -33,  -4, -29, -26,  12,   1,  -9;
/M: SY='L';  M= -15, -38, -45, -36, -18, -48, -36,  26,  -7,  40,  22, -40, -44,  -9,  19, -35, -26,  35, -43, -25;
/I:         I=-26; MD=-27;
/M: SY='A';  M=  33, -45,  26,  25, -53, -35, -34, -49,   9, -49, -42, -18, -39, -23,   6,   0, -12, -40, -55, -44; D=-26;
/I:         I=-26; MD=-27;
/M: SY='E';  M= -12, -58,  27,  45, -63, -48, -18, -61,   1, -57, -51,  -3, -43,  19, -17, -28, -28, -55, -63, -50; D=-26;
/I:         I=-26; MI=-27; MD=-27; IM=-27; DM=-27;
/M: SY='R';  M= -45, -62, -41, -29, -55, -55, -31, -61,  13, -54, -43, -34, -53, -19,  84, -40, -44, -55, -54, -41; D=-26;
/I:         I=-26; DM=-27;
/M: SY='Y';  M=  28, -42, -36, -36,   3, -35, -11, -26, -31, -24, -20, -35,  -9, -27, -31, -24,  -9, -26,  -4,  99;
/M: SY='A';  M=  55, -33, -26,   7, -43, -21, -29, -37,  -4, -38, -31, -22, -32,   0,  11,  41,  -9, -27, -44, -36;
/M: SY='S';  M= -17, -38, -27, -18, -36,  40, -28, -18,   7, -39, -33, -17, -34, -11,  12,  52,  -4, -18, -40,   9;
/M: SY='W';  M= -37, -47, -54, -45,  54, -45, -38, -18, -39,   2, -21, -48, -48, -40, -40, -40, -14,   6, 124,  51;
/I:         I=-30; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='D';  M=   1, -41,  58,  -5, -15, -28, -19, -43,   9, -42, -35,  45, -35,  44,  -8,  -5,   1, -40, -51, -32;
/M: SY='E';  M=   4, -39,  11,  52, -46,   8, -25, -43,  -3, -42, -36, -17, -28,  10, -23,  40,  10, -32, -48, -37;
/M: SY='G';  M= -16, -44,  29,  29, -37,  50, -32, -20, -28,   7, -29, -22,   9, -24, -35, -18, -24, -34,  28, -35;
/M: SY='I';  M=   7, -42, -25,  -1,   2,  -4, -14,  41,   0,  15, -14, -34,  26, -30, -34, -23, -26,  -1, -38,  -3;
/M: SY='G';  M=  11, -40, -28, -14, -46,  71, -14, -48, -27, -46, -37, -18, -34,  -6,  -2,  -2,  13, -40, -43, -40;
/M: SY='P';  M=  28, -41, -29, -12, -42, -31, -27, -35,  30, -21,  14, -25,  40,  32,  34, -11,  -7, -31, -42, -33;
/M: SY='T';  M=  13, -38,  33,  12, -41, -18, -27, -35,  26, -14,  -9, -17,  -3,  17,  -7,  -5,  37, -30, -48, -34;
/I:         I=-24; MD=-25;
/M: SY='I';  M=   5, -41, -49, -44,  22, -47, -43,  61, -42,  20,  25, -42,  12, -39, -44, -36, -27,   7, -37, -20; D=-24;
/I:         I=-24; MD=-25;
/M: SY='E';  M=   0, -39, -14,  41,  -3, -31,  -6,  -5, -21,  33, -15,  19, -38, -14, -31, -22, -25,   7, -44, -28; D=-24;
/I:         I=-24; MI=0; MD=-25; IM=0; DM=-25;
/M: SY='D';  M=  22, -39,  46,  41, -45, -15, -24, -41,   0, -26, -35,  17, -31,   8, -24,  12,  -3, -35, -50, -36;
/M: SY='G';  M= -17, -43,  -7, -38, -50,  84, -35, -56, -34, -53, -42,   2,  -5, -32, -42,  -4, -32, -50, -42, -44;
/I:         I=-28; MD=-29;
/M: SY='K';  M= -22, -44,   4,  19, -32,   2, -26, -34,  47,   5, -26,  -5, -11,   5,  -5, -25,  -2, -31, -38,  15; D=-28;
/I:         I=-28; MD=-29;
/M: SY='A';  M=  29, -38, -24,   7,  -7, -22,  -1, -27, -28,  -5,   7, -29, -38,  -4, -12,  13,  15,  -6, -39,  20; D=-28;
/I:         I=-28; MI=-29; IM=-29; DM=-29;
/M: SY='D';  M=  17, -35,  42,   1, -40, -18,   9, -39, -17, -40, -35,  19, -32, -20, -28,  40,  34, -32, -50,  -7;
/M: SY='L';  M= -19, -38, -19, -17,  48, -49, -33,  -7, -36,  58,  -4, -43, -48, -35,  -2, -39, -30, -13, -30, -12;
/I:         I=-26; MD=-27;
/M: SY='E';  M=   7, -51,  36,  48, -55, -41,  16, -54,  20, -50, -44, -24, -36,   5, -18, -19, -32, -47, -56, -42; D=-26;
/I:         I=-26; MD=-27;
/M: SY='D';  M=  -1, -48,  31,  27, -48, -39, -34, -20,  -6, -29, -41, -26, -40,  -4, -33,  25,   0, -39, -56, -22; D=-26;
/I:         I=-26; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='L';  M= -32, -14, -44,  -7, -12, -52, -35,  20, -18,  64,  19, -45, -46, -33, -37, -41, -28,   5, -40, -22;
/M: SY='A';  M=  55, -35, -12,  44, -18, -25, -29, -35, -21, -36, -31,  -4, -18, -17, -18,   0,  -4, -18, -43, -17;
/M: SY='D';  M=  19, -41,  61,  26, -45, -24,  -7, -41,  18, -17, -34,  12, -32,   4, -21,  -6, -11, -36, -52, -35;
/M: SY='Y';  M= -14, -46, -17, -21,  14, -29,  28,   0,  17, -20, -22, -27, -42, -19,  47, -12, -29, -28,  -1,  65;
/M: SY='A';  M=  54, -14, -35, -30, -35,  -9, -35, -15, -28, -11, -11, -28, -36, -26,  -1,  24,   0,  20, -46, -34;
/M: SY='L';  M=  29, -35, -33,   9,   0, -35, -32,   3,   1,  33,  10, -19, -38, -18, -30,   5, -23,   1, -40, -26;
/M: SY='F';  M=  27, -39,  26,  29,  30, -16, -24, -36,   6, -33, -30,  -3, -34,   1, -10,  -6,  -7, -31, -33,  20;
/M: SY='H';  M= -15, -42,  10,  32, -20, -17,  42, -10,  18,   7, -24,  28, -18, -10,   2, -15, -11, -31,   8, -26;
/M: SY='P';  M= -20, -45,  46,   1, -49,  45, -28, -46, -22, -48, -40,  19,  49, -13, -34, -11,   2, -35, -50, -41;
/I:         I=-28; MD=-29;
/M: SY='F';  M= -58, -62, -47, -66,  47, -73, -56,   8, -65,  13, -30, -65, -71, -41, -63, -62, -52, -22, -43,   2; D=-28;
/I:         I=-28; MI=-29; MD=-29; IM=-29; DM=-29;
/M: SY='D';  M= -12, -46,  66,  47, -52, -26,  -9, -49, -14, -47, -41,  24, -32,  26, -24, -14,  -4, -44, -57, -38; D=-28;
/I:         I=-28; DM=-29;
/M: SY='P';  M=  19, -43, -38, -29, -37, -34, -39,  20, -31, -28, -24, -36,  80, -32, -14,  -2, -22,  21, -46, -38;
/M: SY='Q';  M= -16, -45,  30,  35, -46, -36, -23, -28,  36, -38, -31,  -4,  -5,  52,   6, -21,  -2,  -6, -46, -33;
/I:         I=-24; MI=0; MD=-25; IM=0; DM=-25;
/M: SY='P';  M=  23, -40, -26,  -7, -38, -31,  41, -22, -15,  -6, -24,  23,  43,  17,   9, -19,  10,  -8, -48, -31;
/M: SY='R';  M=  -7, -43, -16,   2, -39, -38,  -8, -11,  33, -25, -27, -22,   0,  12,  58,   0,   4,  -5, -44, -31;
/M: SY='S';  M=  -1, -34, -24, -28, -43,  39, -28, -44, -26, -46, -38,   4, -32, -20, -31,  73,  -9, -37, -47, -36;
/M: SY='G';  M= -16, -42,   7, -36,  19,  65, -30, -36, -32, -14,  27, -11, -38, -31, -14, -11, -31, -36, -33,  12;
/M: SY='R';  M=  26, -43, -28, -19, -44,  12,  50, -45,  26, -40, -29, -20, -18,  27,  51, -19, -28, -38, -44, -28;
/M: SY='Q';  M= -31, -45, -32, -12,  40, -41, -22,  -7, -20,  17,   9, -28, -40,  83, -20, -26, -30, -22, -29,   8;
/M: SY='E';  M= -26, -46,  -2,  87, -45, -44, -23, -17, -11, -36, -34, -26, -25,  -4, -21, -25, -26,   3, -48, -38;
/M: SY='R';  M= -26, -45, -33, -16, -20, -42,  33, -19,  10,  12,  27, -28, -41,  11,  55, -16, -29, -16,  11,  38;
/M: SY='L';  M= -16,  -6, -48, -43,  -8, -49, -33,  21, -42,  59,   5, -45, -48, -37, -41, -38, -10,  11, -33,  29;
/M: SY='E';  M= -29, -46,  42,  66, -50, -36, -20, -49,  36, -46, -40,  24,  -1,  -7, -13, -22, -24, -45, -50, -38;
/M: SY='Q';  M=   6, -38,  -1, -15, -44, -24,  -4, -38, -15, -37,  20,  58, -35,  62,  -3,  26, -15, -36, -49, -32;
/M: SY='L';  M= -31, -38, -45, -39, -15, -50, -15,  39, -24,  51,  12, -40,  -9, -20, -19, -35,  11,   9, -41, -23;
/M: SY='V';  M=  34, -35, -45, -39,  -1, -39, -44,  40, -39,  17, -10, -39, -41, -37, -41, -26,  -5,  40,  -9, -25;
/M: SY='N';  M= -23, -36, -12, -27, -36,  -2, -16,   1, -20, -20,  28,  88, -40,   2, -27, -17, -17,  -7, -55, -34;
/M: SY='D';  M= -29, -46,  43,  36, -46, -16,  31, -32,  -3, -34, -33,  16, -33,  38,  36,  -1, -25, -42, -50, -31;
/M: SY='Y';  M= -11, -45, -35, -36,  26, -20,  68, -24, -32, -11, -17, -31, -45, -27, -30, -30, -31,  -5, -11,  89;
/M: SY='L';  M= -31, -39, -51, -44, -13, -52, -41,  42, -44,  54,  17, -47, -10, -39, -44, -28, -27,  23, -42, -24;
/I:         E1=0; IE=-105; DE=-105;

» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.

Total number of hits	197 in 197 different sequences
Number of true positive hits	197 in 197 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Matrix type [info]	protein_domain
Scaling database [info]	window20
Author [info]	PS_Langendijk_Genevaux
Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

197 sequences

APSI_PECAS  (Q6D5T7), XYLA1_XANAC (Q8PLL9), XYLA1_XANC8 (Q4UTU6),

XYLA1_XANCP (Q8P9T9), XYLA1_XANOR (Q5GYQ7), XYLA2_XANAC (Q8PEW5), 
XYLA2_XANC8 (Q4UNZ4), XYLA2_XANCP (Q8P3H1), XYLA2_XANOR (Q5GUF2), 
XYLA_ACTM4  (P12851), XYLA_ACTP2  (A3N3K2), XYLA_ACTP7  (B3H2X9), 
XYLA_ACTPJ  (B0BTI9), XYLA_ACTS3  (P10654), XYLA_ACTSZ  (A6VLM8), 
XYLA_AGRFC  (Q8U7G6), XYLA_ALLAM  (B9JSR6), XYLA_ARATH  (Q9FKK7), 
XYLA_ARTS2  (A0JXN9), XYLA_ARTS7  (P12070), XYLA_BACC1  (Q739D2), 
XYLA_BACFN  (Q5LCV9), XYLA_BACFR  (Q64U20), XYLA_BACLD  (P77832), 
XYLA_BACP2  (A8FE33), XYLA_BACSH  (E0TVS5), XYLA_BACSU  (P0CI80), 
XYLA_BACSW  (P54272), XYLA_BACTN  (Q8A9M2), XYLA_BACVZ  (A7Z522), 
XYLA_BIFAA  (A1A0H0), XYLA_BIFLD  (B3DR33), XYLA_BIFLO  (Q8G3Q1), 
XYLA_BRADU  (Q89VC7), XYLA_BRUA1  (B2SA37), XYLA_BRUA2  (Q2YMQ2), 
XYLA_BRUA4  (A6X4G3), XYLA_BRUAB  (Q57EI4), XYLA_BRUC2  (A9M9H3), 
XYLA_BRUMB  (C0RHQ0), XYLA_BRUME  (Q8YFX5), XYLA_BRUO2  (A5VPA1), 
XYLA_BRUSI  (B0CKM9), XYLA_BRUSU  (Q8G204), XYLA_BURA4  (B1Z405), 
XYLA_BURCH  (A0KE56), XYLA_BURCJ  (B4ENA5), XYLA_BURCM  (Q0B1U7), 
XYLA_BURM1  (A9ARG7), XYLA_BURO0  (B1KB47), XYLA_BURO1  (Q1BG90), 
XYLA_BURTA  (Q2SW40), XYLA_BURVG  (A4JSU5), XYLA_CALBD  (B9MPG8), 
XYLA_CALSX  (Q9KGU2), XYLA_CERS1  (A3PNM4), XYLA_CERS4  (Q3IYM4), 
XYLA_CERS5  (A4WVT8), XYLA_CERSK  (B9KPP8), XYLA_CHESB  (Q11EH9), 
XYLA_CLAM3  (A5CPC1), XYLA_CLAMS  (B0RIF1), XYLA_CROS8  (A7MNI5), 
XYLA_DINSH  (A8LP53), XYLA_ECO24  (A7ZTB2), XYLA_ECO27  (B7ULC6), 
XYLA_ECO45  (B7MES1), XYLA_ECO55  (B7L6Y0), XYLA_ECO57  (Q7A9X4), 
XYLA_ECO5E  (B5YVL8), XYLA_ECO7I  (B7NP65), XYLA_ECO81  (B7N1L9), 
XYLA_ECO8A  (B7M3I8), XYLA_ECOBW  (C4ZXF6), XYLA_ECODH  (B1X8I1), 
XYLA_ECOHS  (A8A623), XYLA_ECOL5  (Q0TBN7), XYLA_ECOL6  (Q8FCE3), 
XYLA_ECOLC  (B1IZM7), XYLA_ECOLI  (P00944), XYLA_ECOLU  (B7NEL7), 
XYLA_ECOSE  (B6I3D6), XYLA_ECOSM  (B1LJC7), XYLA_ENT38  (A4W566), 
XYLA_ENTFA  (Q7C3R3), XYLA_ESCF3  (B7LTH9), XYLA_FERGO  (Q6T6K9), 
XYLA_GEOKA  (Q5KYS6), XYLA_GEOSE  (P54273), XYLA_GEOTN  (A4IP67), 
XYLA_HAEI8  (Q4QLI2), XYLA_HAEIE  (A5UCZ3), XYLA_HAEIG  (A5UIN7), 
XYLA_HAEIN  (P44398), XYLA_HALH5  (Q9K993), XYLA_HISS2  (B0UT19), 
XYLA_HORVU  (Q40082), XYLA_KLEPN  (P29442), XYLA_LACLA  (Q9CFG7), 
XYLA_LACLS  (Q02Y75), XYLA_LACPE  (P21938), XYLA_LEVBA  (Q03TX3), 
XYLA_LEVBR  (P29443), XYLA_LISW6  (A0AF79), XYLA_MANSM  (Q65PY0), 
XYLA_MARMS  (A6VWH1), XYLA_NOVAD  (Q2GAB9), XYLA_OCEIH  (Q8ELU7), 
XYLA_PARP8  (B2JFE9), XYLA_PARPJ  (B2T929), XYLA_PARXL  (Q13RB8), 
XYLA_PECAS  (Q6DB05), XYLA_PECCP  (C6DIH5), XYLA_PEDPA  (Q03HN1), 
XYLA_PHOLL  (Q7N4P7), XYLA_PHOPR  (Q6LUY7), XYLA_PHOV8  (A6L792), 
XYLA_PRIM3  (O08325), XYLA_PSE14  (Q48J73), XYLA_PSEA6  (Q15PG0), 
XYLA_PSECP  (B8HA51), XYLA_PSEFS  (C3K8E3), XYLA_PSEPF  (Q3KDW0), 
XYLA_PSESM  (Q880Z4), XYLA_PSEU2  (Q4ZSF5), XYLA_RHIE6  (B3Q0R5), 
XYLA_RHIEC  (Q2K433), XYLA_RHIJ3  (Q1MBL8), XYLA_RHILO  (Q98CR8), 
XYLA_RHILW  (B5ZQV6), XYLA_RHIME  (Q92LW9), XYLA_RHIR8  (B9JAF5), 
XYLA_RHOBA  (Q7UVG2), XYLA_ROSDO  (Q162B6), XYLA_RUEPO  (Q5LV46), 
XYLA_RUEST  (Q1GKQ4), XYLA_RUMFL  (Q9S306), XYLA_SALA4  (B5EX72), 
XYLA_SALCH  (Q57IG0), XYLA_SALDC  (B5FLD6), XYLA_SALEP  (B5R4P8), 
XYLA_SALG2  (B5RGL6), XYLA_SALHS  (B4T952), XYLA_SALNS  (B4SWK9), 
XYLA_SALPA  (Q5PLM6), XYLA_SALPB  (A9MUV0), XYLA_SALPC  (C0Q1C2), 
XYLA_SALSV  (B4TZ55), XYLA_SALTI  (Q7C637), XYLA_SALTY  (Q8ZL90), 
XYLA_SERP5  (A8G7W8), XYLA_SHIB3  (B2U560), XYLA_SHIBS  (Q31V53), 
XYLA_SHISS  (Q3YVV0), XYLA_SHOC1  (Q5WKJ3), XYLA_SINFN  (C3M8Y0), 
XYLA_SINMW  (A6UD89), XYLA_SOLUE  (Q022S9), XYLA_STAXY  (P27157), 
XYLA_STRAL  (P24299), XYLA_STRAW  (Q93HF3), XYLA_STRCK  (Q9S3Z4), 
XYLA_STRCO  (Q9L0B8), XYLA_STRDI  (P50910), XYLA_STRLI  (Q9RFM4), 
XYLA_STRMR  (P37031), XYLA_STROI  (Q93RJ9), XYLA_STROL  (P15587), 
XYLA_STRRO  (P22857), XYLA_STRRU  (P24300), XYLA_STRTM  (Q9L558), 
XYLA_STRVO  (P09033), XYLA_TETHA  (O82845), XYLA_THECA  (P56681), 
XYLA_THEMA  (Q9X1Z5), XYLA_THENE  (P45687), XYLA_THENN  (B9K7G3), 
XYLA_THEP1  (A5ILR5), XYLA_THEP3  (P22842), XYLA_THEPX  (B0K1L3), 
XYLA_THESA  (P30435), XYLA_THESQ  (B1LB08), XYLA_THET8  (P26997), 
XYLA_THETC  (P29441), XYLA_THETU  (P19148), XYLA_XANC5  (Q3BMF2), 
XYLA_XANOM  (Q2NXR2), XYLA_YERE8  (A1JT10), XYLA_YERP3  (A7FP68), 
XYLA_YERPA  (Q1C0D3), XYLA_YERPB  (B2K7D2), XYLA_YERPE  (Q8Z9Z1), 
XYLA_YERPG  (A9R5Q1), XYLA_YERPN  (Q1CDB8), XYLA_YERPP  (A4TS63), 
XYLA_YERPS  (Q663Y3), XYLA_YERPY  (B1JH40)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

PDB
[Detailed view]

173 PDB

1A0C; 1A0D; 1A0E; 1BHW; 1BXB; 1BXC; 1CLK; 1DID; 1DIE; 1DXI; 1GW9; 1MNZ; 1MUW; 1O1H; 1OAD; 1QT1; 1S5M; 1S5N; 1XIB; 1XIC; 1XID; 1XIE; 1XIF; 1XIG; 1XIH; 1XII; 1XIJ; 1XIM; 1XIN; 1XIS; 1XLA; 1XLB; 1XLC; 1XLD; 1XLE; 1XLF; 1XLG; 1XLH; 1XLI; 1XLJ; 1XLK; 1XLL; 1XLM; 1XYA; 1XYB; 1XYC; 1XYL; 1XYM; 2G4J; 2GLK; 2GUB; 2GVE; 2GYI; 2XIM; 2XIN; 2XIS; 3CWH; 3GNX; 3KBJ; 3KBM; 3KBN; 3KBS; 3KBV; 3KBW; 3KCJ; 3KCL; 3KCO; 3KTC; 3N4A; 3QYS; 3QZA; 3U3H; 3XIM; 3XIN; 3XIS; 4A8I; 4A8L; 4A8N; 4A8R; 4DUO; 4DVO; 4E3V; 4J4K; 4LNC; 4QDP; 4QDW; 4QE1; 4QE4; 4QE5; 4QEE; 4QEH; 4US6; 4W4Q; 4XIA; 4XIM; 4XIS; 4XKM; 4ZB0; 4ZB2; 4ZB5; 4ZBC; 5AVH; 5AVN; 5I7G; 5VR0; 5XIA; 5XIM; 5XIN; 5Y4I; 5Y4J; 5ZYC; 5ZYD; 5ZYE; 6IRK; 6KCA; 6KCC; 6KD2; 6LL2; 6OQZ; 6QNC; 6QND; 6QNH; 6QNI; 6QNJ; 6QRR; 6QRS; 6QRT; 6QRU; 6QRV; 6QRW; 6QRX; 6QRY; 6QUF; 6QUK; 6RND; 6RNF; 6VRS; 6XIA; 6XIM; 6YBO; 6YBR; 7BJZ; 7BVL; 7BVN; 7CJO; 7CJP; 7CK0; 7CVK; 7CVM; 7DFJ; 7DFK; 7DMM; 7E03; 7NJG; 7XIM; 8AW8; 8AW9; 8AWB; 8AWC; 8AWD; 8AWE; 8AWF; 8AWS; 8AWU; 8AWV; 8AWX; 8AWY; 8WDG; 8WDH; 8XIA; 8XIM; 9XIA; 9XIM
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