General rule information
[?]
Accession |
PRU00748 |
Dates |
3-MAR-2009 (Created) 21-NOV-2019 (Last updated, Version 8) |
Predictors |
PROSITE; PS51415; XYLOSE_ISOMERASE
|
Name |
Xylose isomerase family |
Function |
Xylose isomerase (EC 5.3.1.5) is an enzyme found in microorganisms and plants which catalyzes the interconversion of the aldo sugars D-xylose or D-glucose to the keto sugars D-xylulose and D-fructose. The catalytic activity requires magnesium, cobalt or manganese. |
Propagated annotation
[?]
case <FT:1>
end case
case not <OC:Viridiplantae>
Cofactor |
Mg(2+) Note: Binds 2 magnesium ions per subunit. |
else case <OC:Viridiplantae>
Cofactor |
Mn(2+) Note: Binds 2 manganese ions per subunit. |
end case
case <OC:Bacteria>
Subcellular location |
Cytoplasm. |
end case
Similarity |
Belongs to the xylose isomerase family. |
GO:0009045; Molecular function: xylose isomerase activity.
GO:0042732; Biological process: D-xylose metabolic process.
GO:0005975; Biological process: carbohydrate metabolic process.
GO:0016853; Molecular function: isomerase activity.
GO:0000287; Molecular function: magnesium ion binding.
GO:0046872; Molecular function: metal ion binding.
GO:0006098; Biological process: pentose-phosphate shunt.
case <OC:Viridiplantae>
GO:0030145; Molecular function: manganese ion binding.
end case
case <OC:Bacteria>
end case
case <OC:Viridiplantae>
end case
case <OC:Bacteria>
end case
From: PS51415 |
Key
|
|
From
|
|
To
|
|
Description
|
|
Tag
|
|
Condition
|
|
FTGroup
|
ACT_SITE
|
|
66
|
|
66
|
|
|
|
|
|
H
|
|
|
case not <OC:Viridiplantae>
METAL
|
|
197
|
|
197
|
|
Magnesium 1
|
|
|
|
E
|
|
|
METAL
|
|
233
|
|
233
|
|
Magnesium 1
|
|
|
|
E
|
|
|
METAL
|
|
233
|
|
233
|
|
Magnesium 2
|
|
|
|
E
|
|
|
METAL
|
|
236
|
|
236
|
|
Magnesium 2
|
|
|
|
H
|
|
|
METAL
|
|
261
|
|
261
|
|
Magnesium 1
|
|
|
|
D
|
|
|
METAL
|
|
272
|
|
272
|
|
Magnesium 2
|
|
|
|
D
|
|
|
METAL
|
|
274
|
|
274
|
|
Magnesium 2
|
|
|
|
D
|
|
|
METAL
|
|
304
|
|
304
|
|
Magnesium 1
|
|
|
|
D
|
|
|
else case <OC:Viridiplantae>
METAL
|
|
197
|
|
197
|
|
Manganese 1
|
|
|
|
E
|
|
|
METAL
|
|
233
|
|
233
|
|
Manganese 1
|
|
|
|
E
|
|
|
METAL
|
|
233
|
|
233
|
|
Manganese 2
|
|
|
|
E
|
|
|
METAL
|
|
236
|
|
236
|
|
Manganese 2
|
|
|
|
H
|
|
|
METAL
|
|
261
|
|
261
|
|
Manganese 1
|
|
|
|
D
|
|
|
METAL
|
|
272
|
|
272
|
|
Manganese 2
|
|
|
|
D
|
|
|
METAL
|
|
274
|
|
274
|
|
Manganese 2
|
|
|
|
D
|
|
|
METAL
|
|
304
|
|
304
|
|
Manganese 1
|
|
|
|
D
|
|
|
end case
Additional information
[?]
Size range |
370-420 amino acids |
Related rules |
None |
Repeats |
1 |
Topology |
Undefined |
Examples |
Q93RJ9 (XYLA_STROI); Q9FKK7 (XYLA_ARATH): [Recover all] |
Scope |
Eukaryota
Bacteria |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
[?]