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| Entry: PS51460 |
General information about the entry
| Entry name [info] | GAR |
| Accession [info] | PS51460 |
| Entry type [info] | MATRIX |
| Date [info] |
01-MAR-2010 CREATED;
26-FEB-2020 DATA UPDATE; 14-DEC-2022 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51460 |
| Associated ProRule [info] | PRU00792 |
Name and characterization of the entry
| Description [info] | GAR domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=74; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=69; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.7160497; R2=0.0086696; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=9880.3740234; R2=2.7806418; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=668; H_SCORE=11738; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=437; H_SCORE=11096; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-39; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='T'; M= 16, 21, -15, -46, -88, 9, -36, -25, -35, -38, 5, 35, -53, -38, -30, 25, 49, -57,-100, -85; /M: SY='P'; M= -53, -98, 48, -17, -89, -43, 35, -38, 12, -92, -84, -71, 77, -43, -32, -41, 19, -89, -95, 17; /M: SY='G'; M= 4, -89, -34, -13, -51, 32, 7, -45, 4, -18, -51, 20, -38, 1, -6, 27, 18, -82, -96, -83; /M: SY='D'; M= -27, -37, 51, 24, -17, -29, 25, -84, 7, 10, -78, -12, 40, -43, -14, -30, -76, -47, -98, -80; /M: SY='T'; M= -18, -88, 10, -34, -55, -83, -79, -58, 46, -12, 0, -19, 19, -30, -25, 23, 50, -79, -97, -82; /M: SY='L'; M= -63, -89, -93, -35, -16, -67, -85, 32, -9, 64, -54, -41, -39, -18, -31, -51, -39, -15, -89, -36; /M: SY='D'; M= -19, -91, 74, 3, -94, -18, 23, -46, -72, -89, -31, -21, -17, -13, -36, -11, 49, -46,-107, -84; /M: SY='D'; M= -6, -95, 59, 21, -16, -84, 19, -36, -74, -30, -80, -30, 48, 28, -80, -6, -48, -11,-100, -81; /M: SY='A'; M= 61, -86, -24, 43, -90, -78, -14, -49, -73, -25, 3, -32, -23, 11, -79, -12, 0, -42, -96, -85; /M: SY='V'; M= -23, -89, -96, -91, 24, -48, -92, 33, -58, 2, -62, -48, 21, -90, -34, -84, -74, 64, -90, -11; /M: SY='R'; M= 30, -90, 24, -32, -91, -6, 18, -46, 20, -68, -81, -12, -85, -4, 37, 21, -14, -56, -30, -27; /M: SY='R'; M= -40, -96, 6, 26, -90, -87, 39, -92, 32, -31, -5, 18, 13, -28, 60, -27, -76, -90, -96, -32; /M: SY='I'; M= -40, -37, -85, -46, 4, -15, -81, 35, 17, 13, -66, -31, -51, 32, 16, -2, -54, -3, -87, -4; /M: SY='V'; M= -9, 0, -33, -27, -36, -68, -30, 10, -19, 15, 12, -44, -32, -26, 25, -8, -55, 45, -96, -78; /M: SY='N'; M= 13, 3, 4, 7, -44, -19, 13, -90, -17, -58, -23, 56, -86, -32, 26, 8, 11, -85, 9, -37; /I: I=-16; MD=-40; /M: SY='S'; M= -27,-104, -21, 18,-105, -42, -31, -32, -5, -54, -35, -13, 13, -26, 8, 35, -59, -96,-110, -97; D=-16; /I: I=-16; MI=0; MD=-40; IM=0; DM=-40; /M: SY='H'; M= -59, -95, 9, -16, -87, -23, 49, -45, 20, -23, -78, -12, 27, 12, 47, -12, 11, -86, -95, -9; /M: SY='C'; M= -2, 108, 0, -79, -85, -87, -40, -16, -8, -24, -76, -52, -52, 20, -25, 4, -5, 4,-103, -86; /M: SY='T'; M= -9, -37, 17, -69, -90, -81, 17, -44, 3, -49, -80, 41, 29, -3, 30, 5, 42, -52,-100, -49; /M: SY='C'; M= -33, 109, -78, 15, -91, -8, 8, -45, 7, -86, 9, 4, 18, -18, -80, 8, -74, -59,-103, -88; /M: SY='P'; M= -2, 31, 20, 17, -91, -86, -16, -28, 19, -33, -33, -75, 64, 8, 5, -44, -21, -19, -98, -86; /M: SY='N'; M= -34, -88, 13, -71, -87, -9, 6, -83, 7, -10, -20, 57, 12, 12, -40, 27, 24, -58, -99, -33; /I: I=-24; MI=0; MD=-61; IM=0; DM=-61; /M: SY='K'; M= -18, -28, -76, -2, -89, -15, -79, 9, 32, -44, -76, -28, 30, 29, 26, 18, 5, -25, -94, -83; /M: SY='F'; M= -80, -90, 15, -24, 67, -33, -8, -26, -81, -12, -12, -23, 24, -43, -20, -16, -24, 20, -78, 20; /M: SY='Q'; M= -19, 43, -16, -34, -89, -53, -34, -79, 37, -17, -21, -9, 29, 51, 15, 2, -73, 4, -96, -83; /M: SY='M'; M= -78, -15, 10, 7, 8, -56, -84, 25, -81, 21, 43, -83, -33, -80, -7, -81, -4, 41, -92, -42; /M: SY='Q'; M= -28, -94, -13, 36, 5, -42, -14, 19, -4, -23, -51, -78, -87, 44, -7, -53, -62, 3, 35, 43; /M: SY='R'; M= -81, -97, -73, -6, -87, -89, 56, -94, 50, -89, -78, -34, -86, 30, 78, -41, -78, -54, -90, 12; /M: SY='I'; M= -58, -89, 10, 15, -71, -95, -82, 38, -33, 34, 27, -24, -89, 29, -81, -81, -74, 34, -93, -28; /M: SY='H'; M= 1, -90, 11, -37, -82, 30, 61, -38, 7, -88, -80, -66, -23, 7, -74, 48, -70, -85, -88, 37; /M: SY='E'; M= -77, -96, 25, 70, -93, -34, 55, -93, -11, -26, -81, -68, 4, 25, 19, -21, -19, -90, -98, -80; /M: SY='G'; M= -35, -91, -35, -87, -91, 89, -83, -93, -44, 0, -82, 18, -55, -81, -89, -39, -80, -90, -91, -89; /M: SY='K'; M= -75, -92, -33, -66, -89, 5, 13, -87, 62, -31, -78, -59, -84, 24, 55, 7, -6, -30, -92, -45; /M: SY='Y'; M= -84, -43, -26, -43, -20, -91, -8, -78, 16, -75, -70, -80, -94, -5, 11, -35, -79, -81, -54, 117; /M: SY='R'; M= 0, 9, -78, -72, -37, -83, -75, -50, 4, -12, -76, 21, 7, -3, 73, 12, -37, -40, 35, -78; /I: I=-18; MI=0; MD=-45; IM=0; DM=-45; /M: SY='F'; M= -4, -87, -93, -91, 68, -26, -87, 43, -88, -22, -9, -17, -24, -89, -90, -19, -25, 32, -78, 0; /M: SY='G'; M= -24, -93, -80, -49, -9, 88, -85,-100, -5, -97, -88, -69, 27, -80, -86, -29, -81, -95, -88, -88; /M: SY='D'; M= -12, -90, 64, 45, -92, 5, 9, -88, -31, -21, -83, 14, -81, -67, -76, 2, 20, -49,-102, -84; /M: SY='K'; M= -7, -88, -38, -5, -92, -26, -76, -88, 69, -66, -81, -66, -35, -7, 16, 43, 9, -40, -93, -83; /I: I=-24; MD=-61; /M: SY='Q'; M= -53,-108, 13, -82,-103, -17, 11, -97, -1, 2, -89, -47, 34, 36, -88, 2, -47, -98,-110, -96; D=-24; /I: I=-24; MI=0; MD=-61; IM=0; DM=-61; /M: SY='K'; M= -78,-106, -96, -89, 17,-106, -97, 27, 44, -68, -85, -32, 3, -18, -27, -89, 13, -28,-102, -86; D=-24; /I: I=-24; DM=-61; /M: SY='M'; M= -77, -11, -88, -81, -43, -29, -83, 35, 36, 28, 40, -39, -34, -43, 3, -15, -73, 26, -91, -75; /M: SY='R'; M= -79, 45, -93, -85, -68, -99, -83, 41, -73, 30, -59, -87, -95, -19, 53, -84, -76, 36, -89, 11; /M: SY='F'; M= -83, -87, -92, -90, 92, -43, 6, -26, -85, 14, 19, -23, -94, -88, -18, -5, 12, -68, -70, -14; /M: SY='V'; M= -39, 33, -99, -94, -68,-100, -99, 57, -92, 4, -56, -93, -94, -92, -94, -84, -45, 76, -98, -77; /M: SY='R'; M= -80, -97, -79, -69, -90, 8, -71, -93, 18, -28, -78, -72, -90, -12, 102, -76, -81, -61, -91, -80; /M: SY='I'; M= -40, 37, -85, 15, -30, -47, -82, 51, -75, 6, 44, -82, -88, -6, 19, -47, -4, 15, -90, -14; /M: SY='L'; M= -40, -85, 0, 11, -29, -92, -81, -54, -26, 61, -7, -29, -90, -77, -82, -10, -5, 30, -92, -73; /M: SY='R'; M= -60, -96, -76, -38, -95, 54, 45,-101, -3, -95, -83, -6, -87, 20, 72, -71, -30, -96, -95, -82; /M: SY='E'; M= -70, -91, -45, 54, -95, 28, -19, -96, -17, -50, -86, 31, -81, -1, 4, 52, -56, -91, -97, -86; /I: I=-14; MI=0; MD=-35; IM=0; DM=-35; /M: SY='H'; M= -25, -92, -74, -70, -89, -86, 95, -93, 31, -87, -20, -1, -85, -64, 61, -49, 39, -88,-102, -72; /M: SY='V'; M= -72, -17,-100, -94, -70,-101, -99, 11, -92, 0, 12, -95, -96, -93, -93, -84, -33, 90,-102, -77; /M: SY='M'; M= -78, -86,-100, -90, -12, -93, -73, -28, -84, -9, 138, -88, -89, -77, -82, -88, -76, -9, -89, -66; /M: SY='V'; M= -41, 29, -99, -94, -71,-100,-102, 3, -91, -57, -60, -94, -96, -94, -93, -82, -68, 97,-104, -79; /M: SY='R'; M= -83,-100, -80, -68, -93, -93, -69, -99, -10, -92, -81, -73, -9, -57, 112, -78, -82, -93, -92, -80; /M: SY='V'; M= -70, -84, -99, -93, -70, -99, -99, 30, -91, -55, 13, -93, -94, -91, -92, -25, -68, 93,-102, -77; /M: SY='G'; M= -66, -93, -79, -22,-100, 100, -87,-107, -85,-102, -92, -67, -84, -82, -92, -66, -84,-100, -90, -94; /M: SY='G'; M= -66, -93, -79, -92, -99, 100, -86,-107, -85,-103, -92, -6, -85, -83, -93, -66, -84,-100, -91, -94; /M: SY='G'; M= -66, -93, -14, -90,-100, 100, -87,-107, -86,-103, -92, -66, -85, -83, -93, -66, -84,-101, -91, -94; /M: SY='W'; M= -92,-114,-117, -97, 10, -91,-112, -87, -89, -84, -88,-110, -96, -89, -92, -98,-102,-101, 173, 5; /M: SY='M'; M= 38, -88, 50, 21, -86, -82, -77, 5, -74, -22, 51, -72, -84, 35, -79, -25, -34, -8, -97, -81; /M: SY='T'; M= 14, -86, 70, -9, -92, -30, -79, -84, -74, -88, -84, -62, -20, -74, -81, -4, 72, -34,-105, -85; /M: SY='L'; M= -82, -84, -99, -92, -8,-101, -84, 16, -93, 87, -44, -97, -98, -86, -90, -92, -77, -52, -84, -66; /M: SY='D'; M= 13, -90, 59, 54, -97, 29, -72, -96, 12, -93, -87, -25, -78, -5, -38, 13, -71, -89, -97, -86; /M: SY='E'; M= -76, -95, -18, 92, -94, -12, 79, -98, -34, -89, -82, -32, -75, -9, 1, -71, -77, -64, -98, -77; /M: SY='Y'; M= -87, -91, -92, -92, 91, -94, -65, -68, -86, -62, -66, -88, -98, -86, -83, -34, -80, -73, 27, 106; /M: SY='L'; M= -81, -84, -99, -92, -22,-101, -84, 10, -93, 88, -44, -98, -98, -86, -90, -91, -77, -34, -85, -67; /M: SY='R'; M= -39, -89, 37, -25, -81, -31, 2, -69, 3, 17, -36, -70, -86, 38, 47, -12, -14, 24, -95, -76; /M: SY='K'; M= -38, -90, 5, 42, -35, -86, -73, -79, 72, -4, -74, -19, -80, 8, 6, -38, -36, -4, -91, -78; /M: SY='H'; M= -83, -92, -69, -75, -32, -83, 99, -84, -29, -34, -70, 62, -90, -66, 16, -73, -76, -86, -74, 87; /M: SY='D'; M= 31, -88, 88, -16, 0, -78, -2, -81, -72, -21, -15, -4, -83, 8, -78, -68, -23, -18,-100, -77; /M: SY='P'; M= -12, -93, -78, -8, -87, -81, -4, 6, -6, -27, 18, -45, 94, -73, -80, 31, -28, -47, -93, -84; /M: SY='C'; M= -38, 117, -20, -10, -85, -11, 88, -86, -12, -52, -5, -71, -91, -13, -79, -74, -37, -19,-107, -77; /M: SY='H'; M= -80, -94, -34, -24, -85, -87, 92, -89, -1, -33, 7, -5, -86, -28, 85, -14, -77, -52, -97, -69; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
| Total number of hits | 19 in 19 different sequences |
| Number of true positive hits | 19 in 19 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Feature key [info] | DOMAIN |
| Feature description [info] | GAR |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
19 sequences
DYST_HUMAN (Q03001 ), DYST_MOUSE (Q91ZU6 ), G2L2L_XENLA (A0A1L8HFX9), G2L2S_XENLA (A0A1L8H8C0), GA2L1_HUMAN (Q99501 ), GA2L1_MOUSE (Q8JZP9 ), GA2L2_HUMAN (Q8NHY3 ), GA2L2_MOUSE (Q5SSG4 ), GA2L2_RAT (D3ZUE1 ), GA2L3_HUMAN (Q86XJ1 ), GA2L3_MOUSE (Q3UWW6 ), GA2PE_DROME (Q9W3Y4 ), GAS2_HUMAN (O43903 ), GAS2_MOUSE (P11862 ), K0754_HUMAN (O94854 ), K0754_MOUSE (Q69ZZ9 ), MACF1_HUMAN (Q9UPN3 ), MACF1_MOUSE (Q9QXZ0 ), MACF1_RAT (D3ZHV2 )» more
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| PDB [Detailed view] |
3 PDB
1V5R; 5VE9; 5X57 |
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