PROSITE entry PS51528
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General information about the entry
| Entry name [info] | FLAVIVIRUS_NS3PRO |
| Accession [info] | PS51528 |
| Entry type [info] | MATRIX |
| Date [info] |
01-MAR-2011 CREATED;
07-APR-2021 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51527 |
| Associated ProRule [info] | PRU00860 |
Name and characterization of the entry
| Description [info] | Flavivirus NS3 protease (NS3pro) domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=180; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=175; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3189375; R2=0.0084890; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=27622.0527344; R2=7.4632154; PRIORITY=1; TEXT='Heuristic 0.1%'; /CUT_OFF: LEVEL=0; SCORE=1023; H_SCORE=35257; N_SCORE=11.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=493; H_SCORE=31301; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-42; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='S'; M= 32, -65, -55, -59, -76, 19, -59, -74, -58, -77, -69, 43, -66, -52, -63, 85, -43, -66, -82, -69; /M: SY='D'; M= -60, -76, 75, -47, -83, 53, -56, -84, 37, -84, -75, 56, -68, -54, -55, -51, -58, -81, -86, -72; /I: I=-28; MI=0; MD=-71; IM=0; DM=-71; /M: SY='V'; M= 8, -69, -75, -74, -58, 29, -76, 42, -72, 12, -46, -67, -74, -69, -75, 12, -54, 59, -79, -63; /M: SY='F'; M= -69, -71, -82, -74, 72, -83, -64, -41, -66, 62, 50, -76, -82, -68, 29, -73, -64, -47, -60, -40; /M: SY='W'; M= -64, -81, -84, -76, 37, -73, -82, 58, -71, -52, -55, -74, -75, -69, -75, 37, -63, -49, 139, -38; /M: SY='D'; M= -60, -77, 69, 18, -76, 39, -62, -72, -59, -5, -67, -50, 53, -58, -68, -54, 33, -71, -84, -71; /M: SY='M'; M= -57, -71, -75, -71, -59, 17, -71, 17, -69, 4, 71, -67, 43, -68, -73, -61, 28, 50, -79, -62; /M: SY='P'; M= 15, -83, -66, -56, -82, -66, -68, -72, -57, -79, -67, -67, 112, -62, 18, -57, 19, -71, -79, -78; /M: SY='E'; M= -54, -73, 25, 82, -76, -68, -59, -65, -50, -69, -67, -52, -61, -44, -58, 44, 21, 18, -84, -69; /M: SY='P'; M= 14, -76, -75, -68, 26, -73, -65, 15, -69, 21, -49, -74, 76, -69, -73, -64, -59, 11, -62, 51; /M: SY='P'; M= 5, -80, -52, 62, -76, -70, -61, -71, 25, -4, -63, -62, 77, -48, 21, -59, -59, -69, -77, -71; /M: SY='E'; M= -60, -81, -45, 78, -83, -71, -58, -76, -48, -76, -68, -58, 77, 49, -57, -54, 29, -73, -80, -73; /M: SY='C'; M= 7, 63, -64, 29, -63, -72, -68, -47, -58, 9, -53, -63, -72, -59, 20, 13, 20, 47, -83, -66; /M: SY='H'; M= 19, -72, 22, 27, -63, 6, 73, -68, -58, -64, 47, -51, -66, -52, -61, 23, 20, -65, -75, 36; /M: SY='Q'; M= -61, -77, 63, -42, -79, -68, -58, -66, 45, -71, -64, -48, 30, 69, -48, -53, 30, 8, -83, -67; /M: SY='P'; M= 30, -72, -67, -64, -68, 39, 48, -62, -65, 11, 47, -59, 53, -60, -69, 24, -57, -62, -78, -64; /M: SY='P'; M= -60, -78, 32, 41, 34, 9, -63, -68, -60, -2, -63, -58, 71, -57, -67, 27, -57, -69, -73, -61; /I: I=-22; MD=-57; /M: SY='N'; M= -71, -86, -63, 37, 22, 16, -73, -88, -70, -86, -82, 41, -81, -68, -77, 11, 18, -84, -90, -75; D=-22; /I: I=-22; MI=0; MD=-57; IM=0; DM=-57; /M: SY='H'; M= -83,-101, 32, 14,-100, 5, 63,-106, 35, -99, -89, -67, -86, -68, -68, -77, -83,-102,-106, -82; D=-22; /I: I=-22; DM=-57; /M: SY='L'; M= -61, -70, -75, -68, -51, -80, -70, -37, 14, 64, -39, -71, 27, -66, -66, -65, 28, 36, -76, -59; /M: SY='P'; M= -62, -79, -51, 42, -80, -68, -60, -75, 54, -78, -68, 27, 83, -49, -50, -54, 28, -73, -80, -73; /M: SY='D'; M= 5, -74, 96, 19, -82, -62, -54, -78, -53, -79, -75, 40, -65, -53, -62, -50, 29, -73, -95, -70; /M: SY='G'; M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78; /M: SY='V'; M= 4, -67, -78, -74, 48, -78, -78, 19, -72, -43, -46, -71, -75, -75, -74, -60, 34, 76, -74, -51; /M: SY='Y'; M= -71, -82, -70, -74, -19, -78, -37, -56, -65, -53, -50, -72, -83, -61, -62, -66, -65, -62, -27, 135; /M: SY='R'; M= -61, -79, -62, -52, -76, -71, -53, -81, -28, -75, -65, -54, -73, -41, 109, 35, -59, -74, -77, -63; /M: SY='I'; M= -63, -76, -86, -83, -49, -90, -86, 103, -79, -33, -36, -76, -74, -76, -82, -73, -57, 30, -75, -57; /M: SY='M'; M= -58, -71, -74, -69, 26, -74, -63, 47, 11, -43, 80, -65, -72, -62, -63, 35, -54, 25, -65, 37; /M: SY='Q'; M= 55, -70, -68, -56, -70, -65, -64, -49, -50, -59, -55, -62, -71, 60, 47, -52, -55, 52, -78, -65; /M: SY='R'; M= 27, -74, -61, -52, -76, -65, -59, -74, 42, -74, -64, -55, 29, -47, 76, 14, 20, -67, -77, -67; /M: SY='G'; M= 9, -71, -62, -69, -80, 85, -67, -83, -65, -82, -72, -49, -67, -61, -71, 53, -56, -75, -76, -74; /M: SY='W'; M= -65, -74, -87, -80, 37, -85, -79, 59, -77, 45, -38, -80, -80, -75, -78, -74, -61, 37, 78, -46; /M: SY='C'; M= -68, 78, -85, -79, 75, -82, -68, -43, -76, 54, 59, -77, -84, -76, -75, -73, -64, -48, -62, -41; /M: SY='W'; M= -57, -81, -67, 25, -63, 73, -71, -73, -65, -68, 61, -62, -69, -61, -71, -59, -70, -76, 121, -54; /I: I=-30; MI=0; MD=-77; IM=0; DM=-77; /M: SY='T'; M= -61, -74, -56, -53, -66, -68, -55, -71, 54, -72, -63, 39, 30, -49, 48, -51, 58, -67, -72, 33; /M: SY='Y'; M= -56, -76, -60, -53, -52, -64, -48, -70, 16, -68, -60, -54, -70, 61, 32, 61, -52, -68, -56, 81; /M: SY='Q'; M= -60, -84, -54, -36, -86, -68, 65, -77, -42, -70, -57, -49, -67, 125, -41, -50, -63, -78, -75, -57; /M: SY='I'; M= 36, -72, -74, -67, -60, -74, -74, 65, 15, -47, -47, -67, -72, -62, 30, -60, -56, 44, -77, -62; /M: SY='G'; M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78; /M: SY='V'; M= 38, -68, -80, -74, -56, -75, -82, 59, -73, -42, -43, -74, -74, -72, -76, -61, -53, 74, -81, -62; /M: SY='G'; M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78; /M: SY='Y'; M= -60, -73, -78, -76, -36, -82, -60, 19, -71, -44, -44, -76, -80, -70, -71, -67, -57, 76, -53, 95; /M: SY='M'; M= 43, -71, -75, -71, -55, 34, -66, -49, -67, -52, 80, -67, -72, -64, -70, -57, -60, 31, 76, 34; /M: SY='K'; M= -65, -77, -58, -48, -60, -72, 73, -70, 90, -3, -57, -51, -68, -45, -34, -60, -60, -70, -67, 46; /M: SY='N'; M= -60, -74, 59, 17, -82, -58, -48, -79, -47, -80, -70, 85, -68, 66, -54, 16, -52, -78, -89, -69; /M: SY='G'; M= -53, -75, -55, -67, -81, 88, -62, -86, 15, -85, -73, 60, -69, -60, -64, -49, -62, -82, -77, -75; /M: SY='V'; M= -52, -64, -72, -70, -58, -78, -79, -29, -68, -46, -48, -65, -71, -71, -72, -53, 71, 85, -88, -63; /M: SY='F'; M= -74, -71, -87, -82, 115, -83, -68, -45, -79, 24, -46, -78, -86, -86, -76, -75, -67, -51, -44, -23; /M: SY='H'; M= -65, -75, -51, -55, -69, -67, 133, -79, -56, -69, -57, 43, -68, -50, -55, -52, 41, -76, -99, -44; /M: SY='T'; M= 8, -61, -58, -60, -68, -66, -68, -59, -58, -64, -60, -48, -60, -62, -66, -36, 111, -51, -87, -66; /M: SY='M'; M= -61, -71, -74, -63, -52, -74, -58, -41, -63, 53, 104, -67, -74, 56, -62, 10, -58, -47, -73, -54; /M: SY='W'; M= -73, -92, -93, -78, -37, -75, -76, -64, -70, -60, 57, -87, -79, -68, -72, -78, -79, -75, 164, 62; /M: SY='H'; M= -69, -81, -53, -53, -68, -71, 149, -86, -58, -68, -54, -43, -70, -47, -52, -59, -68, -86,-103, -37; /M: SY='V'; M= -54, 54, -79, -75, -56, -82, -83, 21, -73, -43, -45, -72, -77, -76, -76, -61, 29, 88, -88, -63; /M: SY='T'; M= -52, -61, -57, -61, -67, -68, -68, -58, -57, -63, -60, -47, -59, -62, -66, -35, 115, -50, -88, -65; /M: SY='R'; M= -62, 77, -65, -58, -69, -72, 50, -73, -40, -2, -59, -56, -76, -49, 88, 27, -59, -69, -82, -61; /M: SY='G'; M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78; /M: SY='S'; M= 49, -69, -57, 26, -77, 23, -61, -75, -50, -75, -67, -53, -66, -50, 43, 56, -51, -66, -78, -69; /M: SY='S'; M= 36, -69, 45, -56, -69, -61, -66, -53, -63, -1, -58, -56, 40, -60, -68, 48, -50, 33, -83, -67; /M: SY='L'; M= -65, -70, -85, -78, -43, -87, -73, 47, -78, 77, -31, -82, -81, -72, -77, -75, -61, 16, -73, -55; /M: SY='W'; M= -57, -71, -65, -65, -59, -65, -62, -54, -56, -56, 79, 38, -70, -57, 20, 39, 34, 10, 102, -53; /M: SY='W'; M= -64, -82, -82, -74, -48, -74, 45, 39, -70, 1, -53, -74, -76, -67, -72, 20, -65, 10, 142, -41; /M: SY='N'; M= -61, -76, 25, -48, -80, 17, -51, -80, 39, -79, -68, 71, -70, 49, 52, -52, -57, -78, -81, -68; /M: SY='G'; M= -50, -77, -63, -70, -82, 98, -69, -89, 22, -85, -74, -50, -67, -63, -66, -50, -67, -83, -73, -76; /M: SY='R'; M= -62, -80, -56, 19, -78, 16, -56, -82, 67, -77, -67, -52, -68, -42, 83, -58, -62, -77, -75, -66; /M: SY='R'; M= -59, -72, -61, -58, -63, -68, -58, -56, 25, 29, -53, 42, -73, -51, 62, 35, -54, 8, -79, -62; /M: SY='V'; M= 5, -70, -80, -75, 27, -78, -65, 17, -72, 12, 49, -75, -78, -70, -72, -66, -57, 60, -61, 60; /M: SY='S'; M= -52, -70, -52, 15, -76, 9, -57, -73, -48, -74, -66, 30, -65, 34, 34, 58, 51, -67, -82, -67; /M: SY='P'; M= -66, -82, -72, -61, -66, -73, -68, -55, -67, 36, 47, -75, 109, -67, -74, -67, -60, -61, -76, -70; /M: SY='H'; M= 7, -71, -58, 15, -59, -64, 91, -58, -59, -62, -57, -53, -69, -52, -60, 55, -52, 30, -74, 46; /M: SY='W'; M= -61, -85, -68, 37, -53, -66, -77, -75, -61, -73, -73, -70, -70, -57, -67, 51, -64, -80, 155, -40; /M: SY='G'; M= 58, -71, -58, 38, -80, 71, -67, -79, -61, -77, -69, -55, -65, -57, -68, -47, -60, -68, -75, -75; /M: SY='S'; M= -53, -69, 71, -47, -79, -54, -52, -78, -54, -81, -74, 70, -67, -50, -60, 73, -44, -74, -92, -69; /M: SY='V'; M= 16, -66, -81, -75, -56, -78, -83, 22, -73, -41, -43, -76, -77, -75, -76, -63, -51, 93, -85, -62; /M: SY='R'; M= -63, -76, -66, -56, -55, -77, -57, -53, 60, 9, -52, -61, -74, -50, 64, -63, -60, 30, -65, 51; /M: SY='R'; M= -59, -77, 50, 48, -80, -67, -55, -81, 41, -78, -70, -48, -65, -42, 61, 36, -55, -75, -81, -67; /M: SY='D'; M= -68, -81, 119, -31, -88, -64, -53, -86, -55, -85, -84, -35, -67, -54, -63, -56, -57, -83,-103, -70; /M: SY='M'; M= -63, -72, -79, -72, -42, -82, -60, -36, -63, 51, 63, -75, -80, -63, 28, -70, -60, 41, -63, 60; /M: SY='I'; M= 50, -70, -79, -74, -57, -72, -80, 78, -73, -42, -43, -72, -72, -70, -76, -60, -55, 44, -77, -62; /M: SY='C'; M= 9, 97, -62, -62, -74, -55, -65, -74, -62, -74, -69, -51, -70, -56, -67, 90, -42, -64, -86, -70; /M: SY='Y'; M= -71, -82, -70, -74, -19, -78, -37, -56, -65, -53, -50, -72, -83, -61, -62, -66, -65, -62, -27, 135; /M: SY='G'; M= -54, -75, -64, -75, 47, 91, -67, -79, -69, -74, -70, 28, -71, -68, -75, -52, -66, -77, -67, -60; /M: SY='G'; M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78; /M: SY='P'; M= -57, -81, -63, -55, -82, 6, -66, -76, 14, -82, -70, -60, 105, -59, -64, 48, -53, -76, -79, -77; /M: SY='W'; M= -76,-101,-103, -80, -40, -74,-103, -73, -72, -71, -74, -96, -79, -72, -76, -82, -88, -88, 179, -27; /M: SY='R'; M= 6, -74, -55, -49, -78, -62, -53, -77, 42, -76, -65, 43, -69, 45, 67, 36, -53, -72, -78, -65; /M: SY='F'; M= -69, -71, -86, -79, 70, -86, -70, 30, -78, 70, -34, -81, -83, -76, -76, -76, -64, -39, -60, -41; /M: SY='D'; M= 18, -77, 73, 16, -83, 9, -62, -77, -58, -79, -72, -50, 71, -57, -67, -52, 20, -72, -86, -74; /M: SY='D'; M= 31, -72, 58, -48, -79, 7, -59, -78, 37, -77, -70, -47, -66, -50, 30, 46, -52, -70, -81, -68; /M: SY='K'; M= -58, -74, -57, 16, -70, -68, -60, -64, 60, 19, -57, -55, 40, 35, -46, 27, 21, -64, -76, -65; /M: SY='W'; M= -68, -86, -81, -65, -48, -73, -79, -63, -63, 11, -60, -75, -74, 56, -66, -66, 28, -71, 155, -38; /I: I=-28; MD=-71; /M: SY='N'; M= -66, -79, 25, 55, -79, -74, -63, -62, 12, -72, -69, 59, -73, -55, -61, -61, -60, 39, -93, -75; D=-28; /I: I=-28; MD=-71; /M: SY='G'; M= -70, -96, -71, 39,-102, 71, -84,-108, -78,-102, -93, -70, -83, -74, -87, -70, -84,-100, -94, -95; D=-28; /I: I=-28; MI=-71; IM=-71; DM=-71; /M: SY='T'; M= 17, -68, -53, 29, -76, 49, -62, -74, -57, -75, -68, 29, -64, -54, -64, 37, 51, -66, -81, -71; /I: I=-30; MD=-77; /M: SY='E'; M= -64, -81, 63, 78, -87, -69, -56, -87, -51, -84, -79, 38, -65, -46, -60, 15, -58, -81, -92, -76; D=-30; /I: I=-30; MI=-77; IM=-77; DM=-77; /M: SY='E'; M= -61, -76, 55, 73, 47, -69, -57, -75, 16, -69, -69, -51, -63, -46, -54, 27, -56, -71, -73, -56; /M: SY='V'; M= -52, -65, -77, -74, -56, -81, -82, -23, -71, -43, -45, -71, -75, -74, -74, -59, 42, 96, -88, -62; /M: SY='Q'; M= -60, -78, -65, -48, -67, -75, -58, 36, -52, 10, -46, -60, -71, 108, -52, -57, -60, 23, -74, -59; /M: SY='V'; M= -58, -67, -84, -76, -49, -83, -73, -25, -74, 46, 72, -78, -79, -71, -74, -70, -56, 77, -80, -57; /M: SY='M'; M= -65, -75, -74, -68, -53, -79, 77, 45, -59, 26, 94, -65, -74, -58, 34, -69, -62, -43, -78, -50; /M: SY='A'; M= 61, -67, -71, -65, -67, 8, -71, -46, -57, -57, -55, -65, -72, -61, 42, -52, -55, 59, -79, -67; /M: SY='W'; M= -61, 88, -84, -78, -47, -80, -76, -39, -74, 24, -48, -78, -83, -75, -76, -70, -61, 59, 102, 36; /M: SY='K'; M= -59, -78, -51, 47, -81, -68, -58, -76, 59, -76, -67, -53, 57, 49, -44, 15, 19, -72, -77, -69; /M: SY='P'; M= -65, -83, -55, -56, -83, -62, -60, -74, -58, -84, -70, 74, 112, -61, -69, -57, -55, -79, -84, -80; /M: SY='D'; M= -61, -80, 75, -52, -75, 53, -62, 33, -53, -69, -66, -48, -70, -57, 46, -57, -62, -63, -82, -68; /M: SY='G'; M= 44, -72, -62, -58, -80, 66, -66, -79, 63, -78, -68, -52, -66, -54, -50, -49, -60, -71, -74, -72; /M: SY='P'; M= -58, -73, -62, -59, -67, -67, -65, -55, 13, 19, -56, 25, 77, -60, -63, 27, 30, 9, -80, -68; /M: SY='V'; M= 36, -71, -71, -61, -65, -70, -71, 17, 36, -54, -52, -66, 26, -60, 20, -58, -55, 60, -79, -65; /M: SY='E'; M= -59, -74, -52, 63, -68, -76, -59, -57, -46, 12, -55, -59, -66, 34, 46, -55, 42, 17, -79, -64; /M: SY='N'; M= 3, 68, -60, -68, -55, -65, -55, 14, -62, -53, 71, 75, -76, -61, -66, -57, -54, 9, -73, 47; /M: SY='H'; M= 19, -71, -68, -67, -64, 30, 83, 24, -67, -54, -52, -58, -71, -64, -68, -55, 19, 50, -84, -58; /M: SY='Q'; M= -61, -82, -56, -38, -84, -69, -51, -77, 60, -73, -60, -50, -66, 108, 38, -52, -61, -76, -72, -62; /M: SY='T'; M= -57, -68, -67, -68, -51, -72, -65, 53, -65, 1, -48, -58, -68, -63, -69, 28, 76, -41, -69, 47; /M: SY='K'; M= -57, -70, -60, -52, -66, -68, -61, -60, 63, 23, -54, -52, -65, 34, -46, 28, 60, -58, -77, -63; /M: SY='P'; M= -61, -84, -65, -59, -82, 30, -70, -74, -63, -81, -70, -64, 112, -66, -74, -56, 33, -75, -79, -80; /M: SY='G'; M= 20, -73, -58, -70, -81, 88, -65, -84, -64, -83, -72, 51, -69, -63, -71, -47, -61, -77, -77, -76; /M: SY='Y'; M= -60, -74, -73, -68, -48, -76, -60, 46, -57, 1, 48, -66, -75, -59, 45, 26, -56, 21, -64, 60; /M: SY='F'; M= -66, -72, -83, -79, 83, -82, -64, 30, -74, -39, 47, -76, -81, -76, -73, -71, -61, 41, -50, 61; /M: SY='K'; M= 27, -70, -58, -53, -74, -61, -62, -63, 60, -70, -63, 29, 39, -52, -49, 28, 21, 7, -80, -68; /M: SY='I'; M= -60, -70, -72, -73, -54, -80, -76, 81, -69, 4, -42, -63, -68, -69, -75, -55, 76, -30, -78, -59; /M: SY='D'; M= -65, -80, 85, -45, -79, -66, -60, 11, -58, -74, -69, 27, 75, -59, -68, -56, 19, -67, -90, -72; /M: SY='T'; M= -57, -73, 55, 17, 33, 56, -64, -73, -60, -71, -69, -48, -66, -60, -68, -49, 58, -68, -76, -61; /M: SY='G'; M= -55, -78, -47, 72, -83, 72, -62, -87, 29, -81, -73, -52, -62, -48, -56, -53, -64, -80, -76, -74; /I: I=-26; MI=0; MD=-65; IM=0; DM=-65; /M: SY='K'; M= -58, -73, -51, 43, -76, -69, -58, -75, 70, -74, -66, -50, -62, -43, 37, 16, 51, -68, -78, -66; /M: SY='V'; M= -56, -70, -74, -71, -58, 29, -76, 41, 14, 2, -47, -65, -73, -68, -67, -60, 19, 63, -79, -63; /M: SY='Q'; M= -53, -78, -63, -58, -79, 80, -60, -75, -58, -69, 57, -52, -68, 81, -61, -51, -65, -74, -73, -68; /M: SY='S'; M= 46, -64, -68, -65, 35, -61, -68, -51, -65, -1, -55, -59, -69, -62, -68, 53, 29, 23, -73, -56; /M: SY='I'; M= -57, -73, -80, -80, -55, 29, -83, 75, -76, -41, -43, -71, -75, -75, -79, -66, -57, 66, -79, -62; /M: SY='S'; M= 8, 54, -61, -62, -75, 23, -65, -72, -61, -74, -68, -51, 28, -58, -67, 73, 43, -64, -83, -71; /M: SY='H'; M= -65, -74, -76, -69, -51, -80, 63, 17, -72, 62, -38, -73, 52, -67, -72, -70, -61, 21, -78, -55; /M: SY='D'; M= -66, -78, 106, -39, -76, -68, -59, 34, -58, -68, -69, -41, -67, -58, -66, -56, 20, -61, -95, -67; /M: SY='Y'; M= -72, -77, -75, -75, 82, -80, 49, 14, -70, -47, -49, -70, -82, -69, -67, -69, -66, -54, -39, 100; /M: SY='P'; M= -57, -83, -63, -55, -85, 47, -64, -78, -59, -82, -69, -59, 97, 56, -66, 12, -59, -79, -77, -76; /M: SY='P'; M= -64, -83, -54, 40, -82, -72, -58, -79, 55, -78, -67, -57, 73, 35, 53, -59, -60, -77, -76, -70; /M: SY='G'; M= -51, -77, -67, -77, -75, 95, -73, 33, -71, -71, -65, -53, -69, -68, -78, -52, -66, -64, -74, -73; /M: SY='T'; M= -49, -63, -52, -58, -71, -58, -59, -66, -55, -71, -65, 52, -63, -55, -62, 66, 85, -59, -87, -67; /M: SY='S'; M= -42, -66, -57, -59, -76, 32, -61, -76, -59, -79, -71, -45, -64, -51, -63, 101, -39, -69, -81, -68; /M: SY='G'; M= -49, -74, -63, -73, -80, 96, -70, -83, -67, -81, -72, -49, -66, -66, -75, -47, 41, -76, -76, -75; /M: SY='S'; M= -44, -65, -59, -59, -66, -54, -60, -63, -60, 19, -60, -49, -66, -51, -63, 101, -39, -60, -80, -64; /M: SY='P'; M= -64, -86, -64, -53, -83, -68, -67, -73, 36, -81, -69, -65, 115, -60, -61, -59, 17, -75, -79, -78; /M: SY='I'; M= -63, -76, -82, -76, 36, -84, -80, 78, -75, -40, -43, -76, 52, -76, -79, -70, -58, 46, -71, -54; /M: SY='I'; M= -63, -73, -79, -76, 37, -84, 63, 68, -74, 13, -40, -71, -77, -72, -74, -70, -59, 49, -73, -48; /I: I=-30; MD=-77; /M: SY='N'; M= 49, -73, 53, -56, -83, -60, -61, -77, -61, -81, -74, 72, -73, -61, -68, -50, 19, -71, -94, -76; D=-30; /I: I=-30; MI=-77; IM=-77; DM=-77; /M: SY='S'; M= -58, -73, -66, -57, -59, -71, -62, 24, 40, 43, -47, -59, -71, 33, 19, 44, -54, -51, -74, -60; /M: SY='N'; M= 26, -73, 58, -44, -80, -60, -53, -77, 41, -78, -68, 66, -68, 34, 22, -50, -55, -73, -84, -68; /M: SY='G'; M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78; /M: SY='E'; M= -63, -79, 34, 64, -80, -68, 49, -82, 16, -77, -68, 51, -65, 35, 35, -54, -58, -78, -84, -65; /M: SY='V'; M= -51, -67, -77, -73, -56, -77, -80, 29, -72, -43, -45, -70, -75, -71, -74, 35, -48, 89, -85, -62; /M: SY='I'; M= -59, -72, -85, -80, -50, -87, -84, 78, -77, 7, -37, -78, -77, -76, -79, -71, -55, 70, -79, -58; /M: SY='G'; M= -49, -75, -67, -76, -77, 95, -73, -67, -70, -74, -68, -54, -70, -69, -77, -52, -65, 29, -76, -75; /M: SY='L'; M= -69, -70, -86, -78, 71, -85, -68, -36, -78, 78, -34, -82, -85, -75, -75, -76, -64, -43, -60, -40; /M: SY='Y'; M= -67, -81, -69, -74, -25, 29, -41, -61, -66, -57, -53, -67, -80, -62, -65, -63, -66, -65, -32, 127; /M: SY='G'; M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78; /M: SY='N'; M= -64, -73, -41, 38, -54, -60, -43, -71, -50, -73, -64, 102, -72, -49, -57, -51, -53, -73, -64, 77; /M: SY='G'; M= -47, -74, -63, -72, -81, 96, -69, -87, -67, -85, -74, -49, -67, -63, -74, 37, -61, -81, -75, -76; /M: SY='V'; M= -61, -70, -85, -80, 66, -85, -79, 44, -77, 6, -41, -78, -80, -79, -77, -70, -57, 72, -67, -45; /M: SY='Q'; M= -62, -75, -65, 25, 40, -78, -59, -44, -55, 2, -49, -67, -75, 56, 20, -63, -60, 49, -62, 48; /M: SY='I'; M= -61, -71, -74, -72, -48, -81, 47, 53, -70, 31, -41, -67, -74, -67, -71, -61, 45, 33, -72, 36; /I: I=-30; MD=-77; /M: SY='G'; M= -57, -83, -65, 14, -88, 88, -72, -95, -64, -89, -79, -57, -73, -65, 16, -57, -73, -88, -80, -81; D=-30; /I: I=-30; MI=-77; IM=-77; DM=-77; /M: SY='W'; M= -60, -81, 61, 78, -75, 7, -59, -83, -51, -78, -75, -52, -62, -46, -60, 11, -60, -79, 92, -63; /I: I=-28; MD=-71; /M: SY='N'; M= -68, -85, 22, -68, -92, 56, -67, -94, 13, -95, -84, 69, -80, -66, -69, -60, -68, -92, -94, -84; D=-28; /I: I=-28; MI=-71; MD=-71; IM=-71; DM=-71; /M: SY='P'; M= 2, -83, -73, -65, -80, -75, -74, 21, 27, -74, -69, -66, 52, -63, 20, 21, 18, -64, -87, -76; D=-28; /I: I=-28; DM=-71; /M: SY='Y'; M= -65, -76, -70, -72, 56, -72, -44, -57, -66, -53, -53, -67, -80, -62, -64, 35, -59, -61, -35, 116; /M: SY='V'; M= -61, 52, -76, -71, 48, -81, 63, 17, -63, -47, -49, -67, -79, -68, 29, -66, -59, 65, -75, -48; /M: SY='S'; M= 29, -63, -57, -57, -74, -49, -60, -72, -58, -75, -69, -47, -64, -50, -62, 101, -38, -63, -81, -67; /M: SY='P'; M= 35, -71, -71, -66, -62, -66, -71, 45, -67, 13, -49, -66, 52, -64, -72, 39, -52, 13, -77, -65; /M: SY='I'; M= -64, -77, -78, -77, -52, -86, 72, 94, -74, -37, -39, -69, -74, -69, -75, -70, -59, 26, -79, -53; /M: SY='A'; M= 61, -63, -67, -63, -64, -59, -68, -50, -64, 20, -52, -60, -69, -61, -68, 41, 34, 19, -79, -65; /M: SY='Q'; M= -56, -80, 46, -39, -86, 18, -52, -79, -47, -75, -65, -46, -66, 108, -49, 28, -57, -77, -78, -65; /M: SY='G'; M= 47, -70, -65, -69, -79, 84, -70, -79, -66, -78, -69, -53, -67, -64, -73, -45, 16, -69, -75, -75; /M: SY='D'; M= -58, -76, 56, 50, -80, -64, -54, -81, 38, -79, -72, 29, -64, -43, 32, 40, -53, -75, -84, -68; /M: SY='P'; M= -60, -77, -67, 16, -65, -78, -71, 37, 13, -54, -52, -68, 62, -59, 29, -64, -57, 56, -80, -66; /M: SY='K'; M= -56, -76, -51, 43, -80, 18, -59, -76, 55, -76, -67, -51, 29, 44, -46, 13, 33, -72, -77, -69; /M: SY='Q'; M= 38, -76, 56, 49, -78, -66, -57, 8, -48, -69, -64, -52, -65, 57, 20, -52, -58, -63, -80, -67; /M: SY='E'; M= -58, -73, -47, 84, -65, -78, -62, -49, -53, 20, -54, -63, -64, -48, -61, -59, 20, 40, -81, -66; /M: SY='P'; M= 6, -74, 48, 30, -68, -70, -65, -54, -60, 20, -56, -59, 62, -59, -67, -57, 19, 19, -83, -68; /M: SY='N'; M= -55, -68, 25, 16, -73, -58, -54, -63, -53, -71, -66, 85, -67, -52, -60, 41, 31, 16, -90, -69; /M: SY='P'; M= -61, -74, -57, -59, 38, -63, -61, -67, -59, -71, -65, 60, 87, -62, -68, 16, 42, -68, -76, -61; /M: SY='E'; M= -61, -76, 33, 74, -71, -76, -58, -61, -45, -2, -60, -56, -65, -46, 43, -57, 20, 18, -82, -67; /M: SY='P'; M= 14, -75, -64, 29, -62, 30, -67, 12, -64, -60, -57, -66, 57, -62, -70, -58, -58, 40, -70, 36; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
| Total number of hits | 61 in 61 different sequences |
| Number of true positive hits | 61 in 61 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | Peptidase S7 |
| Version [info] | 3 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
61 sequences
POLG_ALKV (Q91B85), POLG_BANV (C8XPA8), POLG_BUSV (Q32ZE0), POLG_DEN1B (P27909), POLG_DEN1S (P33478), POLG_DEN1W (P17763), POLG_DEN26 (P29990), POLG_DEN27 (P29991), POLG_DEN28 (P14337), POLG_DEN2J (P07564), POLG_DEN2N (P14340), POLG_DEN2P (P12823), POLG_DEN2Q (Q9WDA6), POLG_DEN2T (P27914), POLG_DEN3C (Q99D35), POLG_DEN3I (Q5UB51), POLG_DEN3M (Q6YMS3), POLG_DEN3P (P27915), POLG_DEN3S (Q6YMS4), POLG_DEN4D (P09866), POLG_DEN4H (Q2YHF2), POLG_DEN4P (Q58HT7), POLG_DEN4S (Q5UCB8), POLG_DEN4T (Q2YHF0), POLG_EHV(C8XPB2), POLG_ILHV (Q32ZD7), POLG_JAEV1 (P27395), POLG_JAEV5 (P19110), POLG_JAEVJ (P32886), POLG_JAEVM (G3FEX6), POLG_KFDV (D7RF80), POLG_KOKV (Q32ZD5), POLG_KUNJM (P14335), POLG_LANVT (P29837), POLG_LIV(P22338), POLG_MCFA (P33515), POLG_MVEV5 (P05769), POLG_OHFV (Q7T6D2), POLG_POWVL (Q04538), POLG_ROCV (Q32ZD4), POLG_STEVM (P09732), POLG_TBEVH (Q01299), POLG_TBEVS (P07720), POLG_TBEVW (P14336), POLG_TMUV (G1CRV4), POLG_USUV (Q5WPU5), POLG_WNV(P06935), POLG_WNV9 (Q9Q6P4), POLG_WSLV (C5H431), POLG_YEFV1 (P03314), POLG_YEFVA (Q6DV88), POLG_YEFVC (Q6J3P1), POLG_YEFVE (Q074N0), POLG_YEFVF (Q89277), POLG_YEFVI (Q98803), POLG_YEFVN (Q1X881), POLG_YEFVT (Q9YRV3), POLG_YEFVU (Q1X880), POLG_ZIKV (Q32ZE1), POLG_ZIKVF (A0A024B7W1), POLG_ZIKVK (A0A142I5B9)» more
|
| PDB [Detailed view] |
83 PDB
2FP7; 2GGV; 2IJO; 2M9P; 2M9Q; 2WHX; 2WV9; 2WZQ; 2YOL; 3E90; 3L6P; 3LKW; 3U1I; 3U1J; 4M9F; 4M9I; 4M9K; 4M9M; 4M9T; 5GJ4; 5GPI; 5GXJ; 5IDK; 5T1V; 5TFN; 5TFO; 5WJL; 5WJN; 5WKF; 5WKH; 5YOD; 5YOF; 5YVV; 5YVW; 5ZMQ; 5ZMS; 5ZOB; 6JPW; 6KK2; 6KK3; 6KK4; 6KK5; 6KK6; 6KPQ; 6L50; 6UM3; 6Y3B; 7M1V; 7O2M; 7O55; 7OBV; 7OC2; 7PFQ; 7PFY; 7PFZ; 7PG1; 7PGC; 7VLG; 7VLH; 7VLI; 7VMV; 7VXX; 7VXY; 7ZLC; 7ZLD; 7ZMI; 7ZNO; 7ZPD; 7ZQ1; 7ZQF; 7ZTM; 7ZUM; 7ZV4; 7ZVV; 7ZW5; 7ZWK; 7ZYS; 8A15; 8AQA; 8AQB; 8AQK; 8CO8; 8PN6 » more |