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PROSITE entry PS51532


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General information about the entry

Entry name [info] PITH
Accession [info] PS51532
Entry type [info] MATRIX
Date [info] 01-MAR-2011 CREATED;
10-MAY-2017 DATA UPDATE;
27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51532
Associated ProRule [info] PRU00864

Name and characterization of the entry

Description [info] PITH domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=176;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=171;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.0399852; R2=0.0075324; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=20327.8691406; R2=11.7125607; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=991; H_SCORE=31935; N_SCORE=9.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=593; H_SCORE=27273; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-26; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='S';  M=   7,  22,  35,  17,  -7, -21,  37, -19, -20, -30, -62,  14,  -4, -22, -35,  39, -31,  -1, -82, -62;
/M: SY='H';  M=  -4,  25,  43,  30, -75,  13,  56, -28, -18, -38, -64, -52,  29, -28, -14,  13, -25, -20, -84, -65;
/M: SY='D';  M=  29, -74,  48,  26, -74,  -9,  40, -70,  -9, -36, -64, -12,  35,  -9, -32,  -9,   1, -23, -81, -15;
/M: SY='E';  M=  29, -20,  -4,  38, -38,  12,   5, -13, -35, -26,  -6, -19,  36,  -6, -63,  11, -17, -21, -76, -11;
/M: SY='D';  M= -13, -72,  40,  28, -24,   4, -19, -11, -58,   0, -59,  14, -32, -27, -34,  28,  12,  10, -81, -33;
/M: SY='P';  M=  -5,  22,  30,  -6, -12, -17, -29, -41, -60, -10, -19, -18,  58, -20, -28,   0,  35,  10, -81, -66;
/M: SY='G';  M=  12,  14,  -4,  -1, -30,  34, -62, -40,  13, -18, -22,  15, -15,  -6,   9,  27,  -6, -30, -78, -67;
/M: SY='G';  M= -15, -72,   0, -17, -29,  41, -16,   2, -40,  -5, -16,  33,  35, -60, -67,  23,  15, -27, -79, -66;
/M: SY='Q';  M=  19,  -4, -36,  -3,   6,  18, -15, -42, -34, -17, -22,  14, -24,  54,  -4,  -3, -37, -15, -67,  37;
/M: SY='Q';  M= -19,  -4,  22,  -9,  -6, -66, -56, -36, -36, -61,  22,   1, -70,  52, -16,  32,   6,  11,  42,  46;
/M: SY='S';  M= -53,   1,  61, -35,  -5, -44, -58, -44, -37, -48, -68,  32,  -2, -54, -63,  69,  11, -33, -85, -64;
/M: SY='L';  M= -65, -70, -27, -73, -44, -84, -69,  21, -75,  79,  10, -77, -80, -25, -74, -72,  -6,  -1, -73, -55;
/M: SY='Y';  M= -65, -73, -14, -21,  34, -73,  41, -20, -59,  -3, -20,  33, -75, -30,   1, -38,  31, -11, -56,  79;
/M: SY='D';  M=  -4, -73,  49,   5, -77, -10,   7, -73,  17, -55, -67,  14,  28,   7,  -9,  20,  37, -47, -84, -68;
/M: SY='Y';  M= -11, -20, -67, -32,  54, -74,  47, -32,  13,   2, -52, -62, -75,  43,   8, -41, -36, -39,  11,  65;
/M: SY='I';  M= -61, -73, -82, -78, -49, -86, -80,  84, -26,   9, -10, -75, -75, -73, -75, -69, -14,  50, -75, -17;
/M: SY='D';  M= -17, -16,  94,  22, -83, -61, -53, -53, -28, -80, -75,  54, -67,  -9, -59,  -5, -26, -76, -94, -70;
/M: SY='M';  M= -39, -71, -41, -63,  21, -76,   6,   1,  21,  39,  47, -64, -34,   3, -18, -25,  30,   8,  -8, -52;
/M: SY='P';  M=  -1, -75,  44,   1, -75, -41, -60, -38,  16, -28, -66,   0,  47,  14, -11,  39,   6, -68,  22, -67;
/M: SY='K';  M=   9, -74,   4, -19, -78,  13, -20, -76,  50, -52, -28,  33, -67,  46,  32,   8, -18, -71, -78, -66;
/M: SY='V';  M= -39,  56, -80, -76, -30, -79, -76,  44, -73,  22,  32, -72, -77, -72, -75,   4, -17,  62, -80, -60;
/M: SY='E';  M= -61, -76,  16,  49, -37, -72, -57,   5, -27, -47, -60,   3, -24,  32,  45, -34,  35, -17,   0,  13;
/M: SY='C';  M=  10, 120, -18, -70, -67, -17, -73, -59, -69, -16, -12,   0, -35, -72, -75, -37,  25,  16, -90, -72;
/M: SY='L';  M= -65, -69, -82, -75,   2, -83, -67, -35, -74,  84,  -8, -79, -82, -69, -40, -18, -31, -24,  18, -18;
/M: SY='N';  M= -62, -68,   5, -56, -76, -36, -44, -72, -49, -80, -13, 120, -73, -51, -57, -45, -23, -36, -95, -71;
/M: SY='E';  M=  26, -75, -44,  85, -78, -15, -58, -71, -15, -53, -66, -57, -23,  12, -27,   5, -29, -11, -79, -71;
/M: SY='D';  M=  14,  13,  40,  20, -72, -42, -19, -64,  -6, -16, -62,  15, -67,   7,  -9,  40,   7,   2, -84, -67;
/I:         I=-30; MD=-77;
/M: SY='D';  M=  18, -71,  45,  17, -72, -41, -20, -12, -20, -34, -62,   0, -10, -14, -42,  31,  16,  20, -85, -68; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='D';  M=   6, -76,  47,  44, -78, -27,  22, -74,  11, -38, -67,  19,  43,  -6,  -6, -13, -13, -44, -83, -68;
/M: SY='G';  M= -17, -76,  17, -30,   9,  60,  59, -74, -32, -16, -64,   3,  16,  -3,  -9,  -9, -38, -73, -77, -60;
/M: SY='S';  M=  26, -69, -59, -59, -36,  13, -62, -14, -11, -70, -64,  26,  28, -26, -14,  57,  21, -41, -77, -22;
/M: SY='G';  M=  16,  34, -67, -15,  14,  49, -28, -19, -40,   0, -16, -60,   6, -63, -70,  23, -32, -13,  27, -27;
/M: SY='R';  M=  31, -73,  29,  -8, -75,  -7, -61, -22,  35, -41, -62, -53,  -8,  20,  40,   3, -18, -13, -78, -67;
/M: SY='N';  M=  -3, -72,  -5, -13, -31, -19,  35, -15,  29, -28, -62,  49, -17, -24,  25,  32,  12, -65, -81, -63;
/M: SY='V';  M=  10,  21, -73, -11, -32, -77, -75,  53, -44,   0, -45, -33, -40, -67, -31, -34,  11,  56, -80, -61;
/M: SY='F';  M= -20, -17, -79, -44,  72, -23, -12,  23, -31,  40,   9, -72, -33, -72, -72, -36, -34,   6,  -5, -42;
/M: SY='K';  M= -29, -13, -35,   4,  33, -14, -19, -44,  70, -50, -62, -15, -39,  -4,  46, -39, -42, -69,   0, -21;
/I:         I=-10; MD=-24;
/M: SY='P';  M= -30, -79,  32,  -4, -16,  15, -61, -73,  39, -35, -67,  -3,  63, -26, -15,  10, -58, -47, -76,  -6; D=-10;
/I:         I=-10; MD=-24;
/M: SY='W';  M= -52, -85, -20, -24,  11, -40, -17, -22, -13, -67,   7, -20,  -5, -28, -39,  -4,   2, -21, 114,  48; D=-10;
/I:         I=-10; MD=-24;
/M: SY='W';  M= -52, -90,  30,  45, -37, -83,  39, -24, -10, -26, -74, -66, -79, -22, -41,   2, -71, -51,  53,  -2; D=-10;
/I:         I=-10; MD=-24;
/M: SY='D';  M= -12, -88,  53,  -1, -44, -54, -70, -27,  30, -58,   1, -14, -79,   7, -20, -24, -14, -78, -94, -78; D=-10;
/I:         I=-10; MI=0; MD=-24; IM=0; DM=-24;
/M: SY='R';  M= -49, -94, -40, -36, -88, -89, -15, -85,  23, -22, -76, -14, -89,  -9,  66, -36, -44, -30, -95, -79; D=-10;
/I:         I=-10; DM=-24;
/M: SY='Y';  M= -45, -87,  24,  -3,  -3, -47, -18, -69, -47,  22,   2, -23,  14, -32, -21, -11, -43, -72, -79,  29; D=-10;
/I:         I=-10; DM=-24;
/M: SY='D';  M= -17, -83,  66,  18, -88, -43, -67, -85, -62, -46, -80,  20, -37, -62, -12,   7,  24, -80, -99, -80; D=-10;
/I:         I=-10; DM=-24;
/M: SY='S';  M= -26, -17,  32,  27, -72,   5, -60, -26, -20, -26, -64,  12,  15, -25,  10,  33,  27, -13, -81, -26;
/M: SY='T';  M= -31, -71,   4,  -2, -75,  -9, -59, -69,  25, -50, -25,  13,  25,  12,  15,  38,  51, -40, -81, -68;
/M: SY='D';  M= -43, -21,  27,  -2, -20, -16,  14,   1,  26,   3, -57, -30,  25,  14,  18,   8, -12, -30, -75,  -4;
/M: SY='W';  M= -42,   8, -73,  -5,  54, -48, -60,   4, -68,  -2, -13, -39,   1, -67, -70, -39, -21,   4,  80,  78;
/M: SY='L';  M= -19,   7, -21, -27, -51, -80, -71,   7, -40,  57, -39, -33, -78, -67,  -6, -66, -10,  50, -78, -59;
/M: SY='E';  M= -19,   1, -23,  78, -76, -68,  -3, -71,  14, -27, -65, -29, -62,  23, -31,  38, -35, -18, -80, -68;
/M: SY='S';  M= -30, -66,   7,  -9, -76, -52, -58, -75, -55, -78, -71, -10, -29,   4, -60, 100, -39, -68, -83, -67;
/M: SY='D';  M= -65, -18, 108,  34, -86, -38, -54, -85, -53, -83, -81,  -3, -17, -51, -62, -35, -57, -81, -97, -71;
/M: SY='C';  M=  49,  74,  47, -35, -68, -65, -69,   4, -65, -26, -14, -27, -71, -64, -70, -35,  15,  22, -86, -68;
/M: SY='D';  M= -67, -81, 117,   0, -88, -34, -53, -86, -54, -84, -83, -36, -66, -53, -63, -55, -58, -83,-101, -71;
/M: SY='E';  M= -25,  47,  19,  71, -82, -41,   5, -79, -51, -77, -70,  -5,  62,  22, -59,  -5, -22, -75, -83, -72;
/M: SY='Q';  M= -59, -83, -41,  82, -87, -71, -50, -80, -40, -73, -64, -53, -61, 104, -45, -52, -61, -77, -76, -66;
/M: SY='L';  M= -66, -69, -85, -77, -42, -86, -69,  10, -77,  85,  38, -82, -82, -70, -75, -76, -62, -11, -72, -53;
/M: SY='I';  M= -65, -73, -85, -80, -45, -87, -74,  75, -77,  60,  44, -79, -78, -72, -77, -75, -60,  -8, -73, -55;
/M: SY='I';  M= -65, -72, -85, -80,  46, -86, -74,  66, -77,  45,  36, -78, -79, -75, -77, -74, -60,  27, -67, -47;
/M: SY='H';  M= -45, -74, -13, -58,  29, -66,  88, -20, -28, -37, -57,  56, -72,   0,  14,  14,   6, -66, -72,  33;
/M: SY='I';  M= -35, -74, -84, -81, -26, -87, -84,  91, -77, -19, -38, -76, -75, -75, -80, -70, -35,  53, -76, -57;
/M: SY='P';  M= -24, -86, -66, -37, -82, -30, -70, -70, -63, -79, -19, -70, 119, -65, -74, -60,   6, -39, -80, -80;
/M: SY='F';  M= -75, -71, -88, -83, 120, -83, -68, -48, -79,  -7, -49, -77, -86, -88, -76, -74, -67, -53, -42, -20;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='T';  M= -55, -67, -13, -54, -71, -42, -60, -33,  27, -65,   7,  44, -64,  32, -54,  13,  77,  -3, -84, -65;
/M: SY='Q';  M= -10, -12, -33,  26, -81,  54, -59, -79, -53, -77, -68, -23, -65,  72, -58,  42,  -3, -73, -77, -69;
/M: SY='P';  M=   1, -72,   7, -56, -19, -61,   7, -36, -58, -41, -62,  34,  63,  15, -64,  48,  13,   5, -82, -65;
/M: SY='V';  M= -55,  82, -82, -77, -56, -82, -83, -16, -75,  -5, -45, -75, -81, -78, -77, -65, -13,  88, -89, -64;
/M: SY='K';  M= -61, -21,  -3, -45, -78, -44, -57, -79,  89, -77, -66, -49, -66, -17,  53,   7, -13, -74, -75, -65;
/M: SY='I';  M= -36, -72, -84, -79, -46, -85, -77,  71, -77,  58, -34, -78, -78, -73, -78, -39, -58,  29, -74, -56;
/M: SY='H';  M= -65,   8, -60, -54,  10, -73,  93, -71,  41, -43, -21, -52, -71,   5,  52, -22,   5, -47, -72,  30;
/M: SY='S';  M=  10,  -6, -58, -59, -75,  27, -62, -74, -59, -76, -69, -12, -24, -13, -64,  87,  15, -66, -81, -69;
/M: SY='I';  M= -64, -74, -85, -80, -14, -88, -79,  82, -78,  44, -11, -78, -29, -74, -79, -73, -59,  28, -73, -55;
/M: SY='I';  M= -28,   1, -36, -64, -31, -73,   7,  45,   3,  28,  21,  -4, -73,   9, -22,  21,  -5,   8, -76, -29;
/M: SY='I';  M= -33, -72, -37, -78,  20, -85, -78,  72, -77,  40, -37, -77, -78, -75, -78, -71, -58,  43, -72, -53;
/M: SY='R';  M= -60, -74, -29, -58, -37, -54, -62,  40,  37, -14, -52,   1, -71, -10,  54,   1,  15,  12, -75, -19;
/M: SY='G';  M=  28,  -7, -61, -19, -74,  56, -67, -24, -62, -70, -65,  -1, -35, -60, -69,  36,  41,  -9, -80, -71;
/M: SY='G';  M=   3, -10,  12,  -8, -38,  42, -62, -66, -61,   2, -62,  27,  42, -59, -36,  20, -10, -32, -77,  -7;
/M: SY='P';  M=  23, -74,  35,  16, -77,  -8, -59, -48,   5, -36, -66,  37,  53,  -9, -30,  18, -32, -41, -82, -71;
/I:         I=-12; MD=-31;
/M: SY='D';  M= -58, -76,  67,  19, -81,  27, -23, -51, -56, -58, -73,  39,  24, -54, -30,  29,  -2, -75, -88, -72; D=-12;
/I:         I=-12; MD=-31;
/M: SY='G';  M=  -8, -82,  45,  -2, -82,  49, -15, -35, -66, -38, -74,   3,   2,  -7, -73, -19,  -5, -77, -86, -25; D=-12;
/I:         I=-12; MI=0; MD=-31; IM=0; DM=-31;
/M: SY='S';  M=  -6, -15, -58,   1,  -6, -39,  35, -64, -16, -14,  11,  -2, -67,  37,  15,  51,  30, -38, -77, -23;
/M: SY='A';  M=  55,  41, -59,  -4, -73,  -6,  47, -72, -55, -71, -64, -11, -67, -26,  18,  40,   9, -63, -80, -29;
/M: SY='P';  M= -35, -90, -67, -56, -85, -27, -70, -73, -63, -82, -18, -72, 125, -66, -75, -62, -59, -77, -79, -82;
/M: SY='K';  M= -10, -72, -57, -33, -73, -23, -57, -26,  63, -30, -22,  26, -67, -21,  47,  38,  -7, -66, -77, -65;
/M: SY='T';  M= -30, -71, -35,  21, -67, -69,  43, -26,  35, -24, -19, -12, -65,   3,  22,   0,  62, -33, -79,  -8;
/M: SY='I';  M= -21, -71, -84, -78, -50, -84, -77,  73, -75,  12,  65, -76, -75, -72, -76, -70, -56,  55, -77, -57;
/M: SY='K';  M= -44, -77, -57, -46, -76, -69,  46, -77,  87, -48, -63, -20, -67, -11,  53,  -1, -58, -51, -76, -61;
/M: SY='L';  M=   6, -70, -83, -77, -47, -82, -75,  59, -76,  62, -34, -78, -78, -72, -76, -70, -59,  28, -74, -57;
/M: SY='F';  M= -75, -75, -84, -81, 108, -81, -60, -51, -75, -34, -51, -77, -85, -80, -72, -73, -68, -57,  60,  74;
/M: SY='I';  M=  21,   2, -68, -61, -64, -71, -70,  51,  47, -38, -51, -28, -35, -28,  -9, -13,  20,  26, -78, -64;
/M: SY='N';  M= -63, -68,  15, -31, -78, -51, -43, -77, -48, -84, -71, 122, -72, -50, -57, -45, -47, -79, -96, -72;
/I:         I=-20; MI=0; MD=-50; IM=0; DM=-50;
/M: SY='R';  M= -46, -78, -14, -31, -74, -40, -59, -32, -15, -28, -61,  24,  45,  16,  72, -14,  17,  -7, -81, -67; D=-20;
/I:         I=-20; DM=-50;
/M: SY='P';  M= -44, -79,  34,  27, -80, -27,  45, -75,  10, -77, -68,  18,  65,  -7,   2,  11,  -7, -33, -85, -68; D=-20;
/I:         I=-20; DM=-50;
/M: SY='N';  M= -22, -71,  54, -54,   4,  -6,   3, -26, -57, -70, -66,  61, -37, -24, -37,  29,  31, -16, -84, -30; D=-20;
/I:         I=-20; DM=-50;
/M: SY='M';  M= -37, -72, -47, -77,   5, -84, -72,  57, -76,  51,  66, -77, -19, -71, -76, -73, -60,  15, -73, -54; D=-20;
/I:         I=-20; DM=-50;
/M: SY='D';  M= -25, -75,  98, -41, -82,  25, -57, -80, -57, -80, -11, -15, -66, -56, -65,  24,   0, -76, -92, -70;
/M: SY='F';  M= -46, -10, -38, -81, 118, -82, -68, -17, -78, -41, -51, -75, -85, -87, -76, -73, -66, -37, -43, -21;
/M: SY='D';  M= -40, -76,  87,  45, -82,  -3, -56, -78, -54, -78, -18, -43, -28, -50, -62,  43, -36, -44, -90, -70;
/M: SY='D';  M= -29, -70,  66,  -3, -75, -61, -56, -70, -25, -33, -29,  51, -65, -13, -38,  29,  58, -66, -89, -68;
/M: SY='A';  M=  62,   7, -74, -68, -27, -26,   4,  19, -69,  -5, -50, -67, -72, -67, -72, -53,  -7,  48,   4, -62;
/I:         I=-26; MD=-65;
/M: SY='E';  M=  -5, -77,  44,  59, -81, -23,   4, -39, -16, -77, -71,   4, -65,  11,  10,  37, -32, -73, -85, -70; D=-26;
/I:         I=-26; MD=-65;
/M: SY='D';  M=  -8, -77,  73,  14, -81, -11, -59, -18, -52, -77, -72,  -9, -69,  -3,  28,  38, -16, -71, -88, -70; D=-26;
/I:         I=-26; MI=-65; MD=-65; IM=-65; DM=-65;
/M: SY='M';  M=  -1, -71, -35, -14,  -6, -48, -64, -17,  16,  32,  36,  12,   7, -59,  -8,   0,  32, -35, -77, -61; D=-26;
/I:         I=-26; DM=-65;
/M: SY='K';  M=   6, -20,  -8,  36, -76, -67, -61, -43,  47, -37, -63, -33,  39,  34, -50,   2,  20,  -9, -79, -69;
/M: SY='P';  M=  35,  31, -36,  -1, -81, -41,  -2, -72, -36, -76, -67, -64, 100, -17, -68, -10, -27, -48, -80, -76;
/M: SY='T';  M= -13,  -1,  30, -10, -15, -69, -64,  -9, -31, -47, -57, -15, -67,  43, -62, -16,  66,  36, -83, -63;
/M: SY='Q';  M= -41, -81,   4,  19, -29, -68,   9, -71, -14, -29, -58,  -4, -67, 113, -45, -52, -61, -38, -73, -17;
/M: SY='E';  M= -28, -72, -17,  63, -18, -29, -62,  -6, -19, -47, -60, -55, -63,  16, -25,   3,  57,  12, -80, -65;
/M: SY='W';  M= -45, -10, -79, -26,  39, -81, -13,  45, -12,  48, -41, -75, -77, -18, -70, -70, -20,  -5,  84, -46;
/M: SY='E';  M= -62, -77,  62,  68,  -2, -70,  29, -33, -50, -35, -66,   0, -63,  37, -56, -26,  17, -70, -82, -62;
/M: SY='L';  M= -46, -71, -77, -41,  19, -81,  31,  17, -71,  66,  23, -30, -35, -67, -30, -50, -61,  12, -70, -17;
/I:         I=-30; MD=-77;
/M: SY='P';  M=  21, -72,  22, -19, -69, -67,   6,  -3, -20,   2, -58, -33,  53, -60, -67,  14,  39,  -4, -83, -67; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='P';  M= -37, -79,  -1,  48, -44, -28, -15, -45,   0, -71, -64, -16,  64,  52,  10, -12, -17,   0, -79, -68;
/I:         I=-30; MD=-77;
/M: SY='D';  M= -61, -77,  67,  39, -80, -13,  -4, -33, -11, -76, -70,  23,  34,   6, -28,  -2,  16, -35, -87, -70; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='D';  M= -22, -75,  46,   1,  17,   5,   2, -22, -30, -16, -60,  15,  13,  23, -19,   7, -31,   2,  12,  -7;
/I:         I=-28; MD=-71;
/M: SY='W';  M= -15,  13,  24,  17, -21,   7,  29, -25, -63,  14, -14, -61, -43,  -7, -21, -18,  -8,  21,  54, -60; D=-28;
/I:         I=-28; MI=-71; MD=-71; IM=-71; DM=-71;
/M: SY='G';  M=  -2, -75,  34,  -9, -75,  48,  13,  -8,  17, -69, -64,  11, -26,  -9, -34, -40, -25,  20, -82, -69; D=-28;
/I:         I=-28; DM=-71;
/M: SY='G';  M=   1, -74,  14,  32, -73,  39, -61, -39, -13, -49, -64,   6, -26,  29, -19,  12, -18,  15,   3, -25;
/M: SY='E';  M= -59, -76,  38,  42, -30,  21,   3,  -6, -11,  -6, -59, -33, -24,  15,  -4,  -5,  -6,   3, -78, -16;
/M: SY='E';  M= -24,   9,  21,  31,  10,  17, -64,  13, -36, -15, -57, -38,  23, -59, -28, -11,  -3,  16, -73,  11;
/M: SY='Y';  M= -10, -25,  15,  13, -55,  11,  20,  28, -61, -44, -56, -16,  16,  18, -65, -38,  -1,   1, -65,  63;
/I:         I=-11; MD=-27;
/M: SY='Y';  M= -38, -75, -63,  -2, -56, -46,  30,  -3, -19, -15, -24,   6,  49, -22, -65,   5,   7,  36, -70,  50; D=-11;
/I:         I=-11; MD=-27;
/M: SY='P';  M=  -1, -92, -39, -51, -46, -51, -14, -20, -25, -54, -78,  32,  47, -11,  -9, -38, -16, -50, -95, -30; D=-11;
/I:         I=-11; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='L';  M= -66, -72, -80, -75, -51, -85,  -8, -23, -73,  70, -10, -76, -38, -71, -21, -68,  36,  12, -79, -59; D=-11;
/I:         I=-11; DM=-27;
/M: SY='K';  M= -63, -78, -27, -15, -29, -68, -16, -76,  70, -56, -17,  23,  42,  -4,  53,  -7, -36, -73, -76, -65;
/M: SY='Y';  M=  20, -73, -72, -66,  43, -72, -61,  -3, -56, -20, -52, -67,   8, -62,  45, -15,  -4,  25, -59,  57;
/M: SY='V';  M=  48, -66, -67, -64, -67, -11,  22, -46, -61, -58, -55, -23, -35, -61,   1,  21,  16,  58, -83, -65;
/M: SY='K';  M= -28, -75, -59, -47, -72, -70, -58, -36,  89,  -5,  13, -52, -66,  22,  27, -20, -20, -65, -73, -63;
/M: SY='F';  M= -74, -73, -87, -83, 116, -43, -67, -50, -78, -22, -16, -77, -85, -86, -75, -74, -68, -55,  53,   9;
/M: SY='Q';  M= -55, -75, -52,  -3, -43, -30, -51, -74,   3, -73, -62,  27, -65, 103, -46,  42,   9, -72, -76, -63;
/M: SY='N';  M= -14, -68, -45, -58, -77,  28, -51, -77, -15, -81, -69, 100, -70, -14, -16,  30, -11, -74, -87, -71;
/M: SY='V';  M= -17,  48, -80, -75, -56, -80, -82,  23, -73, -21, -13, -73, -77, -75, -76, -62,  14,  86, -86, -63;
/M: SY='S';  M=  -2, -70, -28,   1, -41, -29,  56, -73, -20, -72, -64,  32, -66,  32,  15,  56,  31, -68, -81, -20;
/M: SY='S';  M= -36,  19,  -6, -33, -72, -37,  55, -35,  -6, -50, -65,  51, -67, -51, -39,  71,  20, -38, -87, -63;
/M: SY='L';  M= -66, -70, -84, -77, -41, -86, -70,  25, -78,  83, -30, -82, -83, -71, -76, -76, -62,   8, -71, -13;
/M: SY='T';  M=  -3, -66, -14, -58, -68, -30,  -1,  -4, -57, -65, -60,   8, -63,  17, -63,  41,  84, -33, -82, -16;
/I:         I=-28; MD=-71;
/M: SY='L';  M= -67, -72, -86, -80,   6, -88, -74,  60, -79,  69,   7, -81, -81, -74, -78, -76, -62,  -2, -71, -53; D=-28;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='F';  M= -48, -74, -78, -76,  98, -42,  59, -18, -73,   1, -48, -70, -82, -74, -70, -70, -66, -55, -45,  62;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='F';  M= -65, -20, -83, -36,  86, -84, -75,  47, -76,  -9,  -7, -77, -34, -79, -76, -71, -60,  48, -59, -38;
/I:         I=-30; MD=-77;
/M: SY='P';  M= -16,   5,  -4,  56, -28, -70, -61, -70,  22, -31, -65, -27,  63,  18, -11,   2, -58, -19, -79, -70; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='D';  M=   3, -73,  70,   6, -79,   1,   1, -76, -38, -77, -71,  32, -66,  -2,   0,  38,   7, -41, -88, -68;
/M: SY='N';  M= -13, -21,  -4, -11, -36, -17, -49, -44, -51, -78, -68, 105, -70,  -4, -59,  18,   4, -71, -89, -69;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='W';  M= -66, -80,  -7,  -3,  44, -73,  -3, -40, -26, -61, -18,   6, -23,  63, -60, -21, -14,   0,  93,  38; D=-26;
/I:         I=-26; DM=-65;
/M: SY='G';  M=  -5, -72,   0, -10,   4,  69, -63, -78, -60, -77, -70,  33, -29, -59, -34,  37,  -2, -73, -76, -67;
/I:         I=-16; MI=0; MD=-40; IM=0; DM=-40;
/M: SY='D';  M= -14, -79,  64,   7, -84,  60, -64, -84, -62, -82,   0,   6,   2, -60, -70, -12, -18, -79, -86, -76; D=-16;
/I:         I=-16; MI=0; MD=-40; IM=0; DM=-40;
/M: SY='D';  M=  27, -75,  52,  35, -82,  23, -63, -76, -39, -76, -19, -52,  -4,   5, -64,  26, -10, -35, -85, -73; D=-16;
/I:         I=-16; DM=-40;
/M: SY='E';  M= -63, -80,  70,  73, -81, -27,  -4, -23, -10, -73,   3, -18, -29,   4, -33, -56,  -4, -72, -86, -69; D=-16;
/I:         I=-16; MI=0; MD=-40; IM=0; DM=-40;
/M: SY='T';  M= -42, -73, -13,  21, -13, -28, -64,   1,  18, -16, -58,  -4, -34,   6,  -5,  -3,  50,  14, -79, -24; D=-16;
/I:         I=-16; MI=0; MD=-40; IM=0; DM=-40;
/M: SY='T';  M= -55,   8, -57,  11, -34, -41,  21,   4, -27, -44, -15,  -6, -64, -57, -11,   5,  87,  -9, -84, -62;
/I:         I=-30; MD=-77;
/M: SY='R';  M= -29, -17, -61,   9, -39,  -4, -59, -18,  32, -48, -61, -57, -71,  31,  65,   9, -39,   0, -74,   4; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='I';  M= -42, -12, -36, -28, -27, -83, -19,  70, -73,  33, -39, -73, -76, -70, -75, -41, -13,  39, -72,  15;
/M: SY='Y';  M= -44, -14,  40,  15,   1, -10,  19, -18, -30, -34, -20,   0, -71,  -9,  -4,   7,   3, -64,  11,  73;
/I:         I=-30; MD=-77;
/M: SY='Y';  M= -33, -77, -68, -20,  39, -24,   2,  15, -25, -23, -53, -25, -77,  -6,  22,   7, -61, -34, -50,  88; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='I';  M= -63,  19, -39,  -2, -12, -54, -72,  61, -69,  52,  -8, -72, -76, -67, -15, -42, -12,   3, -74, -56;
/M: SY='G';  M= -29, -14,  -7,  17, -36,  65, -64, -43,  10, -17, -64, -20, -68, -28,  14,  -2,   5, -28, -77, -68;
/M: SY='F';  M= -66, -72, -80, -26,  63, -26, -69,  25, -72,  54,  -5, -76, -80, -71, -14, -72, -62,  17, -62,  -8;
/M: SY='R';  M= -64, -77, -35,  -2,  31, -18, -62,  42,  28, -11, -52, -62, -19, -22,  54, -23, -36, -21, -66,  14;
/M: SY='G';  M= -30, -76, -63, -11, -33,  92, -11, -47, -65, -22, -68, -53, -69, -63, -14, -52, -39, -75, -72, -28;
/M: SY='E';  M= -43, -74,  16,  67, -70, -25, -18, -28, -30, -27, -23,  13, -64,  -8,  12,   8,  28,  -7, -80, -10;
/M: SY='W';  M=  -4, -23, -67, -21,  47,   9, -66, -61,  -6, -30, -60, -62,  53, -33, -66,  22,  17, -11,  53,  18;
/M: SY='T';  M= -14, -70, -34,  -7,  -1,  29, -66,   6,  17, -19,  -4, -56, -68,   0, -36,   7,  45,  17, -75, -23;
/M: SY='E';  M= -16, -75, -20,  38, -38,  10, -15, -20,  26, -50,  21,  11,  10,  34,   5,   7,  11, -66,  11, -64;
/M: SY='K';  M=  13, -71, -32,  -7, -18,  -9, -12, -59,  42,   3, -10, -56,  -5, -20,   5,  -8,  40, -10,  -6,  -7;
/M: SY='T';  M= -59, -73,  12, -29, -35, -21, -27, -12,  34, -16, -58,  -1,  23,   1,  27, -17,  51,   9, -80, -64;
/M: SY='R';  M= -29, -77,  18,  14, -38,   0,  23, -73,  18, -29, -63,  38, -14, -12,  67, -56, -34, -36, -77, -11;
/M: SY='M';  M= -10, -74,  20,   0, -35,   0, -25,   1,  -8, -19,  75,   3, -14,  38,  13, -11, -12, -24, -78, -61;
/M: SY='Q';  M=  -3, -74, -31, -12, -73,  19,  -1, -23,   8, -37, -13,  26,  34,  43, -15,  20, -13,  10, -79, -67;
/M: SY='V';  M= -29, -72,  38, -12, -67,   5, -24,  -6,  21, -23, -57,  -6,   3, -59, -33, -10,  17,  49, -84, -66;
/M: SY='F';  M=   6,   5, -67,  18,  42, -33, -67,  21, -65,  15, -49, -18, -28, -27, -34, -29,   8,  31, -68,   6;
/M: SY='T';  M=   9,   2, -58,   2, -38, -67,  -9,  25,  34, -46, -56,  21, -24,  22, -27,  -8,  45, -12, -76,   3;
/M: SY='V';  M=   3,  -3, -30, -13, -65, -45, -66,   7,  28,  -3, -53,  14,   5, -30,  21, -36,  14,  41, -80, -65;
/M: SY='Y';  M= -43, -70, -68, -24, -26, -43, -61,  13, -66,  15,   9,   6, -74, -31, -68,  10,  20,  46, -64,  65;
/I:         I=-30; MD=-77;
/M: SY='Y';  M=  16,  -8, -35,  46, -32,  -7, -58, -36,   0, -30, -61,  -9,  26, -54, -32,  -7, -17,  -3, -66,  56; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='E';  M=  22, -72, -24,  45, -68,  28, -11, -65,  -9, -34, -63,  -8,  11, -53, -61,   1,  25,  -4, -74,  21;
/M: SY='S';  M=  25, -71,   5,  24, -40,   6, -59, -44,  26, -31,  11,  13, -67,  -5, -17,  31, -27,  -7, -75,  -1;
/M: SY='A';  M=  42,  -8,  -5,   8, -64,  -2,  -5, -25, -15, -24, -17,   8,  34, -56,   4, -30,  -1, -29, -71,  34;
/I:         E1=0; IE=-255; DE=-255;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.


Total number of hits 14 in 14 different sequences
Number of true positive hits 14 in 14 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] PITH
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
14 sequences

PITH1_ARATH (Q9SQZ9), PITH1_CAEEL (Q95ZI6), PITH1_DANRE (Q6NYX8), 
PITH1_DICDI (Q54Z24), PITH1_DROME (Q9VK68), PITH1_DROPS (Q29L80), 
PITH1_HUMAN (Q9GZP4), PITH1_MOUSE (Q8BWR2), PITH1_SCHPO (Q9P7A1), 
PITH1_XENLA (Q6DJI5), TXL1_SCHPO  (Q9USR1), TXNL1_HUMAN (O43396), 
TXNL1_MOUSE (Q8CDN6), TXNL1_RAT   (Q920J4)
» more

PDB
[Detailed view]
2 PDB

1WWY; 1XOY