PROSITE entry PS51542
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General information about the entry
| Entry name [info] | FYRN |
| Accession [info] | PS51542 |
| Entry type [info] | MATRIX |
| Date [info] |
01-JUL-2011 CREATED;
10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51542 |
| Associated ProRule [info] | PRU00875 |
Name and characterization of the entry
| Description [info] | FYR domain FYRN motif profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=60; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=55; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2239439; R2=0.0097524; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=7988.5214844; R2=1.5923971; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=952; H_SCORE=9504; N_SCORE=11.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=439; H_SCORE=8688; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-28; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='M'; M= -27, -12, -13, -16, 10, -14, -7, -6, 5, 16, 25, 2, 15, -17, -11, -15, 0, 2, -48, -42; /M: SY='P'; M= -40, -26, -35, -36, 37, -70, 13, -10, -35, 12, -1, -28, 66, -39, -42, -19, -27, 14, -90, 5; /M: SY='P'; M= -17, -2, -35, -30, 3, -39, 13, 3, -11, 6, -4, -18, 66, 8, -7, -42, -17, -19, -94, -8; /M: SY='F'; M= -19, -93, -37, -21, 30, -37, -19, 23, 5, 21, 28, -11, -44, -42, 11, -38, -16, 5, -89, -1; /M: SY='R'; M= -10, -94, -39, -8, -8, -39, -11, -14, -5, 16, 33, -13, 1, 4, 41, -38, 2, 5, -35, -54; /M: SY='I'; M= -17, -21, -16, -86, -17, -3, -40, 34, -28, -1, -6, 3, -56, -38, -20, 32, -1, 27, -97, -30; /M: SY='G'; M= -28, 3, -8, 1, -57, 64, 20, -32, -22, -37, -85, -14, 13, -20, -38, -13, 3, -52, -97, -14; /M: SY='S'; M= -11, -8, 24, -53, -70, 26, -15, -59, -8, -66, 42, 30, -16, -11, -26, 55, 6, -59,-100, -55; /M: SY='L'; M= -35, -42, -98, -92, 6, -53, -89, 0, -73, 61, 30, -66, -97, -36, -68, -35, -6, 47, -92, -45; /M: SY='T'; M= -39, -54, -23, 42, -24, -89, -29, 2, -9, -25, 32, -6, -84, 17, 18, -9, 58, -11, -54, -47; /M: SY='V'; M= -52, -90,-100, -63, 23,-102, -96, 60, -93, 29, -58, -96, 22, -71, -74, -68, -75, 60, -92, -73; /M: SY='H'; M= -67, -92, 1, 17, -58, -95, 63, 20, -32, 26, -23, -14, -90, -37, -9, -51, 14, 20, -11, 36; /M: SY='S'; M= -2, 31, 14, 9, -94, -75, -15, -93, 2, -70, -86, 57, -85, -3, 3, 68, -34, -70,-103, -86; /M: SY='L'; M= -58, -89,-100, -95, 23,-101, -39, 36, -94, 71, 17, -53, -56, -89, -93, -41, -32, 0, -86, -13; /M: SY='G'; M= -68, -95, -83, -94, -53, 104, -89,-106, -88, -78, -92, -39, -49, -86, -95, -68, -86, -82, -39, -94; /M: SY='Q'; M= -6, -15, -55, 31, -37, -49, 17, -41, 36, -86, -23, -51, -84, 49, 28, 19, 31, -18, -96, -48; /M: SY='I'; M= -80, -90,-102, -66, -17,-105, -96, 71, -94, 43, -33, -97, -97, -92, -61, -90, -76, 55, -11, -32; /M: SY='V'; M= -35, -40, 18, -26, -34, -93, 29, 27, -52, 9, 9, -21, -6, -27, -42, -10, 6, 53, -98, -17; /I: I=-17; MD=-42; /M: SY='P'; M= -26, -99, -22, -32, -16, -33, -3, -37, -13, -46, -36, -25, 66, -2, -12, 10, 24, -19, 49, 11; D=-17; /I: I=-17; MD=-42; /M: SY='D'; M= -11,-101, 55, -2, -63, 27, 29,-103, -7, -67, -93, 2, -37, -18, 27, -30, -27, -59,-108, -91; D=-17; /I: I=-17; MD=-42; /M: SY='R'; M= -55,-117, -57, -93,-114, -86, -59, -89, -62, -48, -54, 7, -4, 37, 39, 27, -69,-111, -41, -48; D=-17; /I: I=-17; MI=0; MD=-42; IM=0; DM=-42; /M: SY='P'; M= -8, -33, 20, 24, -38, -7, -50, -63, 36, -66, -21, -20, 60, 8, 4, 10, -20, -59, -96, -45; D=-17; /I: I=-17; DM=-42; /M: SY='N'; M= 19, -28, -15, -49, 1, 26, 29, -83, -6, -1, -12, 35, -6, -58, 4, 19, 2, -45, -35, -24; /M: SY='F'; M= -65, -93, -95, -91, 92, -41, -80, -75, -59, -46, -1, -25, -36, -38, -11, 20, -81, -60, 92, 55; /M: SY='H'; M= -53, 68, 23, -74, -13, -1, 117, -93, -22, -72, -78, -34, -90, -9, -77, -16, -29, -33, -51, 13; /M: SY='N'; M= -50, 31, 31, -51, -60, -30, 19, -66, -4, -43, -83, 58, -19, -31, -51, 48, 49, -56,-104, -53; /M: SY='E'; M= 1, -94, 36, 44, -34, -35, -11, -57, 40, -74, -68, -32, 17, 17, -3, 23, -40, -32, -95, -21; /M: SY='R'; M= -21, -37, 17, -13, -39, -16, 41, -55, 21, -73, -63, 13, -27, 34, 46, 7, 23, -38, -24, -3; /M: SY='Y'; M= 41, -3, -63, -34, 11, -85, 56, -48, -6, -47, -3, -23, -91, -15, -24, -30, -18, -18, 11, 81; /M: SY='I'; M= -36, -26, -98, -61, -70,-101, -96, 87, -93, 22, -5, -63, 28, -90, -96, -49, -43, 15, -93, -53; /M: SY='Y'; M= -71, 0, -97, -95, 74, -70, -73, -20, -89, -29, -70, -48,-101, -89, -88, -88, -51, -35, 94, 102; /M: SY='P'; M= -84, -6, -85, -75, -50, -87, -88, -89, -81, -50, -86, -60, 126, -84, -54, -53, -55, -68, -97, -98; /M: SY='V'; M= -4, -40, 13, 4, -79, -68, -91, 39, 10, -19, -67, -61, 12, -48, -83, -66, -21, 66,-100, -82; /M: SY='G'; M= -69, -95, 1, -88,-100, 100, -86, -63, -70,-103, -93, 4, -45, -52, -92, -68, -84,-100, -94, -95; /M: SY='Y'; M= -91, -95, -95, -95, 85, -98, -65, -70, -88, -50, -44, -92,-102, -88, -85, -87, -84, -52, -51, 116; /M: SY='R'; M= -66, 26, -44, 12, -89, -89, 8, -56, 47, -51, -15, -38, -85, 22, 53, -15, 48, -3, -45, -53; /M: SY='C'; M= 50, 76, -48, -81, -86, -64, -86, -11, -81, -81, -21, -74, -87, -78, -86, 65, 14, 11,-100, -50; /M: SY='S'; M= -50, -5, -58, 27, -43, -57, -39, -14, -11, -34, -18, -58, -84, -10, 47, 50, 49, -3, -43, -50; /M: SY='R'; M= -56, -46, -84, -73, -86, -94, -27, -81, 12, -69, -78, -64, -92, -32, 101, -79, -20, 26, 67, -76; /M: SY='I'; M= -8, -90, -62, -27, -30, -56, 19, 32, 28, 27, -12, -46, -57, 3, 6, -27, 16, 13, 16, -25; /I: I=-16; MD=-40; /M: SY='Y'; M= -77, -27, -98, -71, 69, -85, -1, -75, -92, -38, -29, -94, -32, -91, -63, -34, -60, -14, -27, 102; D=-16; /I: I=-16; MD=-40; /M: SY='W'; M= -4,-102, -99, -43, 37, -50, -15, -35, -20, -31, 0, -46, 5, -61, -4, -45, -17, -36, 121, 28; D=-16; /I: I=-16; MD=-40; /M: SY='S'; M= -50, -35, -20, -80, -27, -66, 21, -53, -50, -97, -91, 9, -90, -46, -25, 91, -65, -37, -11, -85; D=-16; /I: I=-16; MD=-40; /M: SY='M'; M= -38, 8, -60, -91, -18, -29, -33, -8, -52, -2, 43, -87, 29, -89, -28, 4, 41, 23, -23, -37; D=-16; /I: I=-16; MD=-40; /M: SY='K'; M= -25, -20, -10, -50, -2, -47, -16, -29, 34, 3, -80, -55, -97, -12, 29, -14, 9, 10,-102, -85; D=-16; /I: I=-16; MI=0; MD=-40; IM=0; DM=-40; /M: SY='D'; M= -21, -4, 81, 0,-101, -46, 25,-102, -23, -92, -95, 46, -49, -60, -5, 0, -27, -92,-112, -29; D=-16; /I: I=-16; DM=-40; /M: SY='P'; M= 8,-101, -23, -47, -49, -14, -31, -24, -13, -9, -60, -9, 95, -7, -53, -48, -29, -63, -99, -92; D=-16; /I: I=-16; DM=-40; /M: SY='W'; M= -45, -93, 41, -5, -27, 9, 27, -36, 8, -41, -42, 39, -22, -37, 36, -8, 17, -45, 43, -20; /M: SY='K'; M= -31, -24, -9, 16, -26, -12, -24, -79, 45, -50, -81, 17, -15, 38, 42, 11, 11, -29, -95, -82; /M: SY='R'; M= -43, -41, -32, -24, -60, 14, -20, -4, 31, -6, 12, -61, -25, -28, 67, -1, 3, -35, -33, -21; /M: SY='C'; M= 5, 102, -89, -25, -14, -75, -91, 7, -85, -61, 3, -41, -93, -19, -64, 6, 22, 47, -51, -83; /M: SY='W'; M= -60, -16, -71, -3, -6, -92, -17, -4, 4, 12, -2, 0, -25, -28, 34, -14, 23, 14, 75, 18; /M: SY='Y'; M= -71, -11, -91, -92, 33, -62, 13, -44, -60, -59, -8, -89,-100, -81, -82, -62, -83, -26, 55, 123; /M: SY='T'; M= -44, -90, -22, 13, -64, -92, 8, 36, 27, -23, -17, -33, -85, -13, 22, -48, 58, 11, -96, -17; /M: SY='C'; M= -9, 119, -89, -88, -15, -84, -86, -19, -85, -37, 65, -16, -95, -31, -89, 50, -71, -45,-102, -84; /M: SY='E'; M= -53, -94, -38, 75, -94, -87, -9, -56, 25, -67, -18, -50, -8, 9, 35, 28, 9, -66, -96, -45; /M: SY='I'; M= -77, -91, -99, -96, -41, -61,-101, 90, -63, -55, -58, -90, -92, -91, -52, -44, 8, 57, -96, -76; /M: SY='L'; M= -30, -7, -14, 24, -35, -46, 8, -6, 7, 40, -27, -28, -89, -34, -8, 4, 19, 10, -94, -21; /M: SY='D'; M= -39, -6, 76, 59, -95, -37, -47, -9, -27, -49, -85, -4, -45, -8, 10, -34, -25, -15,-104, -86; /M: SY='G'; M= 14, 34, 15, -15, -50, 45, -35, -71, -15, -78, -83, 31, -59, 18, -8, 2, 7, -7, -8, -25; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 24 in 24 different sequences |
| Number of true positive hits | 24 in 24 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 1 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 96.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | FYR N-terminal |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
24 sequences
ATX1_ARATH (Q9C5X4), ATX2_ARATH (P0CB22), JM703_ORYSJ (Q53WJ1), JMJ14_ARATH (Q8GUI6), JMJ15_ARATH (O64752), JMJ16_ARATH (C0SUT9), JMJ18_ARATH (F4I6G4), KMT2A_HUMAN (Q03164), KMT2A_MOUSE (P55200), KMT2B_HUMAN (Q9UMN6), KMT2B_MOUSE (O08550), KMT2C_HUMAN (Q8NEZ4), KMT2C_MOUSE (Q8BRH4), KMT2D_HUMAN (O14686), KMT2D_MOUSE (Q6PDK2), MBD9_ARATH (Q9SGH2), TBRG1_HUMAN (Q3YBR2), TBRG1_MOUSE (Q3UB74), TBRG1_RAT (Q5PQK8), TBRG1_XENTR (Q66IH2), TRR_DROME (Q8IRW8), TRX1_ORYSJ (Q6K431), TRX_DROME (P20659), TRX_DROVI (Q24742)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
1 sequence
JMJ13_ARATH (F4KIX0) |
| PDB [Detailed view] |
1 PDB
2WZO |