PROSITE entry PS51543
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General information about the entry
| Entry name [info] | FYRC |
| Accession [info] | PS51543 |
| Entry type [info] | MATRIX |
| Date [info] |
01-JUL-2011 CREATED;
10-MAY-2017 DATA UPDATE; 13-SEP-2023 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51542 |
| Associated ProRule [info] | PRU00876 |
Name and characterization of the entry
| Description [info] | FYR domain FYRC motif profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=83; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=78; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2525024; R2=0.0088431; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=12243.3154297; R2=1.7950000; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=990; H_SCORE=14020; N_SCORE=11.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=481; H_SCORE=13107; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-36; D=-200; I=-200; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='G'; M= -41, 15, 35, 18, -64, 55, -37,-124, 19, -23,-115, 7, 22, -55, 5, -5, -35,-121, -18, -39; /M: SY='P'; M= -25, -24, 31, 29, -61, 31,-108, -44, -9, -32, 5, 23, 47, -32, -32, 21, -9, -53,-127, -39; /M: SY='G'; M= 7,-121,-109, -43, -20, 46, 15, -37, 32, -35, 8, 2,-117, 2, 36, 1, -18, -27,-120, -1; /M: SY='P'; M=-112, -31,-117,-107, -47,-119,-118, -38, -34, 8,-107,-121, 121,-115,-121, -66,-106, -3,-125,-121; /M: SY='L'; M=-108, -22, -54, -18, -53, -66,-113, 26, 12, 42, -8, -51,-121, 7, 0, -8, 8, 36, -17, 8; /M: SY='F'; M= -76, -26, -64,-128, 124,-129,-114, -55,-125, -90, -99,-122, -48,-133,-123, -73, -66, -39, -90, 2; /M: SY='R'; M= -58,-123, -11, 44,-119,-120, -17, -65, 24, -41, -42, -20, -47, 27, 68, -28, 9, 26,-127,-112; /M: SY='V'; M=-104,-118,-129,-125, -99,-131,-128, 72, -61, -30, -2,-122,-124,-121, -64, -28, -60, 84,-127, -40; /M: SY='T'; M= -28, -5,-108, -7, -49,-115, -27, 1, -24, -80, -34, -27,-114, -14, 21, 42, 75, 11, 17, -23; /M: SY='S'; M= 12, 25, -6, -59,-111,-112,-111, -38,-108, 12, 26, 2, 42, -31, -15, 48, 5, 21,-127, -30; /M: SY='E'; M= -4,-123, 51, 67,-121, -36, -10, -6, -10, -25, -27, -35, -31, 6, -34, 10, -6, -23,-130,-114; /M: SY='D'; M= -68,-123, 96, 35,-128, -27, -15,-128, -61,-127,-122, 35, -61, -44, -34, 13, 11,-124,-138, -41; /I: I=-22; MD=-42; /M: SY='D'; M= -45, -28, 64, -43,-135, -58, -16,-134, -16, -55, -14, 38, -35, 20, -28, -3, -32, -83,-146, -21; D=-22; /I: I=-22; MI=0; MD=-42; IM=0; DM=-42; /M: SY='P'; M= -80, -42, -28, -9,-140, -3, -48,-131, -48, -30, -41,-127, 85, -12, -71, -16,-123, -42, -4,-136; D=-22; /I: I=-22; DM=-42; /M: SY='D'; M= -74,-125, 52, 50,-128, 47, 7, -67, -3, -66, -42, 11, -29, -99, 1, -8, 5,-123,-132,-119; D=-22; /I: I=-22; DM=-42; /M: SY='F'; M= -39,-121, -39, 33, 51, -50, 3, 24, -13, 9, -98, -19,-120, -14, 2, -42, 2, 23,-116, -7; D=-22; /I: I=-22; DM=-42; /M: SY='P'; M= -63, 34, -62, 12, 9, -52, -31, 8, 26, -13,-103, -58, 38, 3, -15, 17, 13, 21,-121, -4; /M: SY='F'; M= -77, -45,-126,-123, 71, -57, 37, 50, -35, -7, -5,-118,-125,-118,-118, -33, -31, 13, 70, 47; /M: SY='E'; M= -31, -35, -17, 62, -26,-117, -40, 8, -7,-109, -37, -39,-112, 17, 9, 31, 27, 21,-126, -46; /M: SY='G'; M= 34, -4, -1, -28, -63, 79, 20, -57, -53,-124,-117, -34,-115,-107, -43, 25,-106,-119,-124, -50; /M: SY='S'; M= -2, -12, 35, -16, -37, -43, -9, -76, 13, -47,-112, 22, 24, -54, 15, 45, 27, -19, -26, -42; /M: SY='S'; M= -26, -38, 22,-102,-120,-104, -38,-115, -46,-119,-114, -24,-111, -36,-109, 91, 63, -32,-133,-114; /M: SY='P'; M= 45, 33,-117,-109,-119, -67, -31, 10,-113, -19, 15,-115, 96,-112,-120, -20, -24, -32,-126,-119; /M: SY='D'; M= -33,-118, 60, 25,-123, -57, -3,-120, -17, -81, -40, 24, -53, -29, -70, 54, 58,-115, -1,-114; /M: SY='E'; M= 30,-120, 29, 41, -57, 16, -39, -32, 23, -59, -33, 8, -43, 1, -21, 14, -20, -23,-127,-115; /I: I=-8; MD=-15; /M: SY='C'; M= 63, 95,-122,-116,-117, -74,-123, -63,-117, -35, -27,-116, 40,-117,-122, -56, -62, 42,-132,-120; D=-8; /I: I=-8; MD=-15; /M: SY='W'; M=-129,-152,-154,-134, -11,-128,-150,-123,-126, -76,-124,-148,-134,-126,-129,-135,-139, -81, 174, -4; D=-8; /I: I=-8; MD=-15; /M: SY='Q'; M= -17,-135, -14, -3,-137,-126,-118, -66, 19, -48,-125, 19, -40, 34, 26, 14, 16,-128,-142,-128; D=-8; /I: I=-8; MI=0; MD=-15; IM=0; DM=-15; /M: SY='V'; M= -47, -37, 0, 10, -60, -55, -35, 3, -51, -44,-125, -4, -64,-128, -15, -27,-126, 26,-153,-134; D=-8; /I: I=-8; DM=-15; /M: SY='I'; M= -20,-140, -57,-138, 14,-145, 30, 43, -73, 12, -36, -63,-143, -47, -68, -67, -60, -2,-140,-118; D=-8; /I: I=-8; DM=-15; /M: SY='E'; M= -59, -26, -21, 27,-135, -14, 3, -21, 9, -48, -45, -19, 0, -4, -20, -11, -23, -11,-143, -62; D=-8; /I: I=-8; DM=-15; /M: SY='K'; M= 5, 30, -11, -31,-129, -32, 0, -8, 38, -30,-117, -57, -26, 4, 9, -1, -12, -32,-137,-123; D=-8; /I: I=-8; DM=-15; /M: SY='I'; M= -23, -15, -18, -27,-113, -46, -38, 45, -45, 13, -13, -64, -28, 14, -22, -59, -59, 42,-134,-116; D=-8; /I: I=-8; DM=-15; /M: SY='Q'; M= -21, -40, -61, 19, -1,-127, 22, 24, -69, 10, -13, 6, -65, 44, 3, -71,-112, 20,-126, -2; D=-8; /I: I=-8; DM=-15; /M: SY='Q'; M= -75, -58, 26, 40, -53, -59,-108, -20, 36, -36, -37, 24, 7, 47, -12, -31, 7, -40,-131,-117; D=-8; /I: I=-8; DM=-15; /M: SY='K'; M= 28, 3, -34, 8, -1, -5,-111, -25, 38, 12, -47, -59,-119,-104, 14, -6, 2, -63,-120, 12; D=-8; /I: I=-8; DM=-15; /M: SY='R'; M= -20, -8, -15, -6, -61, -20,-110, 21, 10, -12, 1, -1,-121, 17, 68, -64, -61, 8, -9,-111; D=-8; /I: I=-8; DM=-15; /M: SY='R'; M= 10, -12, 15, -2,-119, -38,-106, -34, 31, -22, -17, 34, -49, 23, 37, 22, -17, -16,-127, -52; /M: SY='E'; M= 13, 11, 21, 42, 7,-113, 12, -43, 35,-114, 20, 31, -60, 12, 19, 1,-104, -56,-123, -13; /M: SY='A'; M= 30,-119, 23, -23, -20, -14, 19, 11, -41, 21, -4, 2, -64, 19, -38, -5, -52, 17, -10,-107; /I: I=-44; MI=0; MD=-84; IM=0; DM=-84; /M: SY='Q'; M= -17, 3, -3, -2,-113, 12, -45, -34, 21, 28, -11, 30, 5, 31, 16, -20,-106, -27, -19, -46; /M: SY='R'; M= -19, -57, -2, -13, -29, 11, 33, -62, 8, 13, 18, -2, 29, -10, 36, 9, -9, -28,-125,-109; /M: SY='P'; M= -27, -10, 7, -33, -8, -25, -25, 2, 22, 3,-104, 5, 48, 12, 14, 4, -4, 2,-125,-110; /M: SY='K'; M= -31, 27, 1, 17, -39, 14, 3, -44, 36, -11, 1, -27, 23, 0, 11, 8, -29, -7,-125, -39; /M: SY='W'; M= -54, -35, 13, -9, -24, 15, -5, -17, 12, 20, -45, -16, 21, 9, 22, 3, 6, -27, 22,-109; /M: SY='P'; M= -3, -43, -30, -15, 25, -47, 10, -22, 26, -14, -37, -53, 59,-104, 29, 17, -25, 0, -28, -51; /M: SY='S'; M= 2, 13, -43,-109, 10, -37,-112, -8, 5, 20, -12, 4, 39, -27, -5, 44, -40, 1,-123,-108; /M: SY='T'; M= 3, 9, -12, 9, 4, -25,-110, 5, -8, -1, 9, 21, 24, -2, -28, -6, 33, -16,-123, -17; /M: SY='S'; M= 9,-119, -11, -11, -1, -10, -7, -36, 9, -64, -41, 0, 16, 6, 15, 42, 30, -82,-119, 25; /M: SY='W'; M= -53,-122, -63, -43, -4, -8, -56, 56, -6, 7, -14, -52, 1, -30, -43, -51, -43, 51, 66,-103; /M: SY='S'; M= -40, 3, 30,-101,-118, -37,-105, -75, -7, -16,-112, 50, -18, 0, -8, 74, -3, -74, 9, -39; /M: SY='G'; M= -69,-124, 12,-117,-126, 100,-116, -45, -51, -80,-119, -98,-116,-113,-121, -55, -32, -46,-122, -40; /M: SY='P'; M= 0, -40, 0, 34, -6,-116, 43, -24,-105, 0, -43, -50, 71, 23, -56, 0, -3, -28,-124, -16; /M: SY='D'; M= -28, -30, 71, 68, -57, -72, -12, -21, -44, -81,-115, -14,-112, 30, -1, 1, -58, -49, 14, -24; /M: SY='M'; M= -23, -43,-126,-119, 61, -49, -10, -23,-112, 30, 103,-117,-124, -50, 16, -31,-109, -48,-109, 21; /M: SY='F'; M=-121,-120,-133,-129, 119,-130,-112, -22,-125, -3, -30,-124,-133,-131,-122,-121,-114, -99, -89, 42; /M: SY='G'; M= -16, -1,-112,-121,-128, 104,-118,-133,-116, -55,-119, -99,-116, -32,-123, -60,-114,-127,-122,-124; /M: SY='F'; M=-116,-118,-132,-125, 76,-132,-115, -5,-124, 75, -21,-127,-131, -33,-122,-122,-111, -24,-106, 1; /M: SY='T'; M= 4, -40, 21, -29,-118, -6, -20,-110, -14, -11,-109, 17, -66, -21, -43, 56, 58, -15,-131,-114; /M: SY='H'; M= -11,-119, 20, 6, -29,-112, 77, -46, -55, -4,-105, 64,-117, -29, -20, 18, 8, -4,-130, -7; /M: SY='P'; M= -27, -11, 21, 3,-129, -72, -25,-121, -7, -79,-116, 14, 105, -14, -14, -13, -40, -54,-129,-122; /M: SY='T'; M= 27, -38, -15, 13, 26, -42, 14, -36, -11, -22, -27, 5, 16, -3, 10, -27, 29, -10, -17, 5; /M: SY='V'; M= -46,-117,-130,-125, -98,-132,-128, 66,-123, -14, -36,-124,-125,-122,-124,-115, -39, 86,-125, 4; /M: SY='Q'; M= -1, -2, -60, -65, -69,-119, 29, 18, -2, -5, 31, -49,-119, 63, 24, 1, -6, 28,-124, -23; /M: SY='R'; M= -19,-124, -21, 14, -13, -75, 9, -65, 39, -60, -35, 35,-117, 30, 64, -3, -75,-117,-116, 44; /M: SY='L'; M= 21, -6,-121, 6, -56,-124, -33, 29, -65, 65, 18,-121, -39,-111, -34, -71,-107, 0,-120, -9; /M: SY='I'; M= -58,-120,-130,-126, -10,-132,-123, 82,-122, 48, 31,-123,-124,-119, -62,-117, 5, 12,-121,-102; /M: SY='E'; M= -49,-126, -89, 91,-127,-117,-101, -78, -10, -58, -13, -10,-109, 66, 11, 16,-105, -59,-126,-115; /M: SY='Q'; M= 20, -35, -56, 35,-125, -16, -8,-121, 15, -43, -55, 8,-112, 75, -22, 49, -30,-116,-126,-113; /M: SY='L'; M= -50, -5, -59,-119, -57, -60,-113, -84,-120, 83, 66, -26, -54, -17,-119, -32,-108, -41, -2,-102; /M: SY='P'; M= -24,-130, 19, 18,-125, -63, -30, -66, -55, -25,-113, -50, 109, -56, -39, 1, -65, -58,-127, -44; /M: SY='G'; M= -40,-122, 19, -61,-122, 72,-108,-122, 9, -55,-115, 52, -19, 1, -52, 2, -52, -24,-124, -9; /M: SY='A'; M= 65, -36, -62, -9, -6, -58,-116, 21, -44, -66,-102, -5,-117,-108, -38, 24, -42, 38,-124, -42; /M: SY='D'; M= -19, -35, 61, 43, -57, -75, 50, -40, 10, -31,-111, -6, -38, 7, 34, -16, -29, -33, -15,-110; /M: SY='K'; M= 8,-120, -17, -19, -57, -49, 18, -68, 56, -39, -55, 18, 8, 6, 15, 30, 16, -41, -7, -30; /M: SY='C'; M= -29, 131, -63, -69, -47, -55,-120, -6, -75, 29, 8,-115, -33, -42,-123, -10, -33,-102,-132, -47; /M: SY='S'; M= 8,-117, -61, -5, -26, -19, -31, -34, 28, -27,-107, -2, -5, -2, 5, 46, 38, 7,-126,-111; /M: SY='N'; M= -55, -7, 40, -5,-121, 9, -17, -14, 54, -74, -45, 54, -51, -23, 18, -9, -27, -43, -10, -35; /M: SY='Y'; M= -34,-126,-116, -14, 26, -70, -27, -64, -54, -27, -37,-116, -36, -27, -32, -24, -52, -46, 4, 121; /I: I=-44; MI=0; MD=-84; IM=0; DM=-84; /M: SY='W'; M= -33, -31, -54, -7,-114, -73,-109, 3, 47, -22, -31, 12, -64, 51, 35, 4, -7, -3, 77,-107; /M: SY='F'; M= -31,-124, -47, -46, 70, -50, -9, -48, -6, -57, 20, 17, 44, 7, 50, -36, -24, -79, 35, -25; /M: SY='R'; M= -4, -38,-112, -13, -45,-119, -37,-103, 45, 26, -28, -62, -64, 26, 51, -15, -2, 7, 47, -42; /M: SY='F'; M= -7, -26, -5, 19, 58, -81, 17, -27, 12, -25,-104, 16, 13, -65, -41, -9, -16, -19,-109, 54; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 24 in 24 different sequences |
| Number of true positive hits | 24 in 24 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 1 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 96.00 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Feature key [info] | DOMAIN |
| Feature description [info] | FYR C-terminal |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
24 sequences
ATX1_ARATH (Q9C5X4), ATX2_ARATH (P0CB22), JM703_ORYSJ (Q53WJ1), JMJ14_ARATH (Q8GUI6), JMJ15_ARATH (O64752), JMJ16_ARATH (C0SUT9), JMJ18_ARATH (F4I6G4), KMT2A_HUMAN (Q03164), KMT2A_MOUSE (P55200), KMT2B_HUMAN (Q9UMN6), KMT2B_MOUSE (O08550), KMT2C_HUMAN (Q8NEZ4), KMT2C_MOUSE (Q8BRH4), KMT2D_HUMAN (O14686), KMT2D_MOUSE (Q6PDK2), MBD9_ARATH (Q9SGH2), TBRG1_HUMAN (Q3YBR2), TBRG1_MOUSE (Q3UB74), TBRG1_RAT (Q5PQK8), TBRG1_XENTR (Q66IH2), TRR_DROME (Q8IRW8), TRX1_ORYSJ (Q6K431), TRX_DROME (P20659), TRX_DROVI (Q24742)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
1 sequence
JMJ13_ARATH (F4KIX0) |
| PDB [Detailed view] |
1 PDB
2WZO |