PROSITE entry PS51562
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS51562 |
| Entry name [info] | RNA_CAP0_MT |
| Accession [info] | PS51562 |
| Entry type [info] | MATRIX |
| Date [info] |
01-NOV-2011 CREATED;
22-FEB-2023 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51562 |
| Associated ProRule [info] | PRU00895 |
Name and characterization of the entry
| Description [info] | mRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.56) domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=286; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=281; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2489257; R2=0.0087920; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=1792; N_SCORE=18.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=484; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-37; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='S'; M= -59, -67, -43, -29, -42, -26, -30, -81, -30, -27,-111, 28,-114, 5, -7, 88, 24, -57, -38, -28; /M: SY='P'; M= -37,-123, -29, 7, -33, -75, 5, -13, 19, 3, -14, -26, 50, 21, 41, 4, 22, -33,-124, -49; /M: SY='I'; M= 3, -14, -55, -37, -12, -36, -27, 77, -51, -11, -37, -81, -74, -6, 12, -27, 26, -27,-120, -15; /M: SY='Y'; M= -31,-122, -66, -8, 32, -21, -27, 30, 29, -7,-100, -44, -68, -2, -2, 17, -30, -6, 3, 53; /M: SY='H'; M= -2, -28, -23, -50, -36, 19, 62, -59, -4, -22, -19, 25, 46, 3, -5, -15, -27, -17,-120, 36; /M: SY='M'; M= -65,-119,-127,-118, -17,-129, -12, 15, -90, 71, 82,-121,-126, 7, 0, -82, -68, -32,-118, -23; /M: SY='R'; M=-112,-127, -12, -57,-121, -31, -30, -85, 27, -52, -49, -15,-120, -54, 106, -36, -26, -78,-124, -47; /M: SY='N'; M= -1, 1, 14, -17, 8, -62, 13, -45, 18, -82,-111, 78,-118, 7, 29, 4, -30, -24,-126, -18; /M: SY='F'; M= -50,-120,-129, -96, 107,-128, 34, -15, -83, 20, -19,-121,-130,-124,-120, -92, -91, -41, -15, 34; /M: SY='N'; M= -82,-118, -90, -51, -35,-105, 97, -32, -99, -94, -47, 110,-119, -38, -70, -5, -40,-121,-140,-105; /M: SY='N'; M= -45,-115, -44, -56,-121, -55, -93, -78, -58, -43, -32, 125,-120, -59, -78, -17, -63,-121,-139, -66; /M: SY='W'; M= -82, -52, -85, -33, 63,-123,-121, -74, -63, -18, -34, -73, -72, -37, -63, -39, -60, -55, 152, 47; /M: SY='V'; M= -17, -52,-129,-125, -53,-129,-126, 74,-122, -24, 1, -63,-123,-121,-124, -61, -34, 76,-124, -4; /M: SY='K'; M=-109,-124,-103, -90,-125,-117,-106, -84, 116,-123,-112, -96,-111, -88, -73, -53, -70, -37,-120,-113; /M: SY='S'; M= 9, -47, -73, -29, -69, -48,-107, -85, 23, -61,-113, -46,-113, -13, 14, 86, 23, -90,-125, -23; /M: SY='V'; M= -16, 23, -38, 2, -80, -73, -19, 32, -18, -17, 41, 8, -72, 16, -4, -21, 16, 46, -48, -35; /M: SY='L'; M= -48,-118,-129,-122, -51, -83,-116, 34, -72, 79, 51,-124,-127, -41, -41, -76, -26, -22,-120,-102; /M: SY='I'; M=-113, -54,-132,-129, -2,-136,-126, 104,-124, 9, -14, -91,-123, -78, -79, -77,-107, -34,-116, 5; /M: SY='Q'; M= -9,-121, -10, -31, -45, -3, -12, -18, 18, -60, -66, 54,-117, 64, -10, 24, -23, -70,-117, 47; /M: SY='T'; M= -46, -32, -2, 37, -45, -44, -2, -31, 43, -5, -8, 10,-113, 21, 5, -1, 44, -58,-125, -31; /M: SY='Y'; M= 15, -13,-120,-119, 62, -65, 19, -1,-115, -37, -20, -30,-125, -67, -82, -12, -35, 4, -96, 95; /I: I=-8; MD=-20; /M: SY='C'; M= 17, 67, -89,-119, -18, -37,-121, 14, -70, 16, -29, -76, -77,-116, -73, 26, 21, 37,-128, -37; D=-8; /I: I=-8; MD=-20; /M: SY='Q'; M= -9,-127, 18, -11, -90, -49, 3, -88, 33, -90, -76, 26, 31, 39, 11, 31, -27, -56,-131, -44; D=-8; /I: I=-8; MD=-20; /M: SY='K'; M= -43, -34, -25, -8, -27, -53, 0, -53, 49, -26, -45, -20, 27, 13, 36, -24,-116, -91,-132, -36; D=-8; /I: I=-8; MD=-20; /M: SY='I'; M= -33, -15, -42, -32, -29, -96, -62, 6, -38, -8, -1, -89, -34, -42, -56, -79, -5, -3,-152, -93; D=-8; /I: I=-8; MI=0; MD=-20; IM=0; DM=-20; /M: SY='N'; M= -25, -23, -19, -11, -56, 0, -86, -44, -2, -83, -63, 28, -39, -11, -9, 9, -19, -31, -57, -43; D=-8; /I: I=-8; DM=-20; /M: SY='P'; M= -28, -64, 4, 5, -62, -28, 24, -58, 14, -99, -66, 25, 47, 12, 22, -5, -50, -70,-135, -29; D=-8; /I: I=-8; DM=-20; /M: SY='G'; M= -27, -2, 12, -9,-120, 41, 12, -99, 24, -79, -48, 38, 25, 9, 23, -5, -15, -89,-124, 11; /M: SY='D'; M= 19, 8, 35, -22, -11, -16, -48, 2, -8, 18, 15, -9, 5, 14, -46, 8, -20, -31, -21, -35; /M: SY='T'; M= -3, -14, -34, -71,-112,-113, -15, -13, 17, -60, -19, 6, -67, -39, 47, 38, 48, 5, 32, 1; /M: SY='V'; M= -36, -66,-130,-124, -75,-131, -62, 30,-122, 29, -23,-126,-126,-122, -88,-115,-102, 91, -29, -71; /M: SY='L'; M= -69, 27,-131,-125, -11,-132, -54, 24,-124, 85, 6,-128,-130,-119, -88,-122,-109, -18,-119,-101; /M: SY='D'; M= -37,-127, 120, 21,-134, -80,-101,-133,-101,-130,-129, -85,-113, -99, -82, -49,-105,-128,-146,-118; /M: SY='L'; M= -85,-119, -73,-125, 1,-133,-116, 52,-123, 76, 49,-126,-128,-118, -76,-122,-109, -29,-115, 2; /M: SY='C'; M= 62, 86, -20,-115, -47, 62,-116,-122,-114,-120,-115,-105,-119,-112, -60, -14, -67,-113,-123, 5; /M: SY='C'; M= -25, 143,-125,-125, -9, -52,-124, -36,-121, -84,-110,-114,-133,-125,-126, 5, -77, 12,-135, -14; /M: SY='G'; M= -97, -46, -48,-122,-130, 108,-118,-138,-117,-134,-123, -71,-116,-115,-124, -97,-115,-131,-122,-125; /M: SY='K'; M= -81, -59,-104, -93,-125, -81, 11,-126, 93,-123, -58, 5,-115, -26, 74,-105,-107, -69,-123,-111; /M: SY='G'; M= -29,-123,-112,-123,-129, 106,-118,-134,-117, -89, -75, -98,-116,-114,-124, -69, -72, -86,-121,-124; /M: SY='G'; M= -5,-123,-110, -74,-129, 99,-115, -87,-113,-128, -23, -32, -67, 30,-119, -43,-112,-126,-122,-122; /M: SY='D'; M= -83,-128, 126, -79, -74,-112,-101,-133,-102,-131,-131, -83,-115,-102, -72,-103,-105,-130,-149,-117; /M: SY='L'; M= -49,-118, -76, -78, -8, -58, -56, 42,-122, 77, 43, -61,-126, -30,-121,-119, -37, -41, -47, -73; /M: SY='M'; M= -36,-123, -4, -17, -14, 20, 41, -25, -5, 12, 48, 13, 26, 19, -4, 0, -35,-109, 4, 1; /M: SY='K'; M=-110,-125,-103, -90,-125,-118,-105, -68, 114, -94,-112, -96,-111, -88, 10, -72,-105,-121,-119, -60; /M: SY='W'; M=-121, -25,-137,-125, 35,-123,-120,-110,-118, -51, 22, -71,-128, -72, -75,-124,-124, -95, 162, 75; /M: SY='Y'; M= 12, -7, 6, -2, 14, -79, -42, 23, 25, -11, -50, -26,-119, 16, 16, -6, -20, -16,-114, 45; /M: SY='H'; M= -31, -59, 10, -25, -10, -38, 60, -36, 49, -38, -20, 29,-117, 21, 13, -2, -34, -20,-118, 39; /I: I=-17; MD=-44; /M: SY='A'; M= 63, 12,-111, -76,-119, 19, 1, -59, -26, -25, -7, 21, -79, 0, -27, 28, -31, -17,-127, -69; D=-17; /I: I=-17; MI=0; MD=-44; IM=0; DM=-44; /M: SY='N'; M= -50, -64, -19, 4,-125, 39, 12,-126, 47, -63,-114, 51, -12, 16, 51, -25, -67, -88,-126, -83; /M: SY='I'; M= -9, -65,-127,-122, -74,-128, -78, 71,-120, 9, -63, -69, 30,-119, -62,-113, -17, 61,-124, -14; /M: SY='S'; M= 6, -54, -2, 2, -95, 30, 4, -98, 41, -64,-113, -17,-114, 11, 25, 44, 7, -68,-125, -39; /M: SY='H'; M= -83, -15, -34, 36, 49, -36, 78,-112, 8, -18, -23, 13,-118, -6, -7, -12, -4, -50, -40, 39; /M: SY='Y'; M= -89,-120,-126,-123, -2,-129,-106, -5,-119, 34, -1,-124,-129,-116, -74, -78, -83, 60, 11, 96; /M: SY='V'; M= -74, -21, -52, -93, 34, -88, -7, 37, -86, 8, -27,-120,-125,-121,-122, -86, -4, 79,-120, 4; /M: SY='G'; M= 9, 48,-115,-122, 3, 93,-118,-123, -85, -40, 9,-102,-118,-115,-123, -99, -61, -70,-121,-117; /M: SY='I'; M= 8, 3,-126,-122, 1,-126, -52, 64,-120, 12, -13,-119,-123, -72,-122, -91, 18, 58,-122, -8; /M: SY='D'; M=-115,-128, 125, -28,-135,-112,-101,-134,-102,-132,-131, -59,-114,-101, -71,-103,-105,-130,-150,-118; /M: SY='I'; M= -38, -59,-123, -63, -48,-127,-123, 90, -22, -21, -65, -24, 32, -35, -75, -13, -41, 19,-123, -50; /M: SY='S'; M= 65, -10, 56, -69, -85,-101, -10,-119,-106,-121,-115, -44, -66, -69,-111, 72, -56, -75,-131,-116; /M: SY='E'; M= 20,-121, 25, 44, -55, -46, -17, -80, 19, -15, -37, 1, 14, 5, 7, 17, -13, -45,-124, -3; /M: SY='E'; M= 0,-120, 38, 43,-120, -29, -6, -48, -10, -71, -48, 33, -46, 5, -1, 4, 17, 30,-131, -80; /M: SY='S'; M= 28, 13, -53, -2,-122, 18,-107, -86, -78, -82, -16, 44, -69,-100, -61, 82, -93, -54,-129,-117; /M: SY='I'; M= -93,-120,-131,-127, -95,-134, -62, 82,-124, 51, 4, -71,-125,-121,-125,-120, -81, 43,-123, -65; /M: SY='E'; M= 12, -65, 32, 53, 1,-114, 23, -7, 20, -66, -40, 9,-113, 23, -15, 3, -11, -43,-123, -3; /M: SY='Q'; M= -32, -77, 27, 64, -73, -52, 1, -19, -95, -89, -62, 45, -73, 72, -40, 18, -23, -62,-128, -44; /M: SY='A'; M= 80, 76, -61, -56, -53, -37, -86, -70, -33, -24, -75,-110, 19, -73, -5, -27, -54, -62,-125, -69; /M: SY='R'; M= -14,-122, -16, -4, -35, -79, 12, 13, 31, -19, 27, -11, -66, 28, 57, -58, 6, -1,-122, -16; /M: SY='D'; M= -12,-124, 61, 47, -73, -33, -19, -79, 2,-122, -76, 11, -75, 39, 46, 0, -11, -88,-129, -40; /M: SY='R'; M= -61, -67, -68, -56, -80, 37, -48,-128, -24, -78,-113, -23,-120, -48, 106, -25, -74, -84,-123, -61; /M: SY='Y'; M= 46, -42,-119, -68, 16, -69, 3, -23, -19, -32,-101, -76,-123,-109, -45, -40,-109, -25, 73, 101; /I: I=-8; MD=-21; /M: SY='C'; M= -36, 55, -28, 41, -44, -55, 3, -5, 17, -29, 11, 40, -78, -4, -9, -7, -9, -67,-128, 0; D=-8; /I: I=-8; MD=-21; /M: SY='S'; M= 9, -53, 13, 27, -99, -5, -53, -50, 6, -65,-118, 13, -82, 10, -19, 43, -9, -18,-134, -82; D=-8; /I: I=-8; MD=-21; /M: SY='M'; M= -54, -26, -40, -69, -6, -78, -28, -25, -79, 8, 71, -14,-133, -21, 60, -20, -54, -83,-130, -11; D=-8; /I: I=-8; MD=-21; /M: SY='Y'; M= -28, -54, -57, -65, -52, -55, -8, -45, 3, -33, -52, 11, -72, -44, 10, -71, -45, -28,-120, 76; D=-8; /I: I=-8; MD=-21; /M: SY='N'; M= -25, -29, -20, -11,-136, -17, -68, -32, -11, -10, -44, 34,-137, 8, -19, -4, -25, -66,-147, -65; D=-8; /I: I=-8; MI=0; MD=-21; IM=0; DM=-21; /M: SY='R'; M= -56, -52, -43, -77,-145, -21, -53, -88, 39, -61,-134, -15, -57, -4, 41, -17, -57, -68,-147, -70; D=-8; /I: I=-8; DM=-21; /M: SY='R'; M= -37,-137, -34, -19, -64, -34, -40,-136, 49, -62, -67, 20, -48, -31, 50, -10, -59,-133, -61, -16; D=-8; /I: I=-8; DM=-21; /M: SY='R'; M= -23,-131, -12, 0, -31, -7, -42,-128, 36, -81, -42, 2, -22, 13, 41, 8, -7, -65,-130, -11; D=-8; /I: I=-8; DM=-21; /M: SY='R'; M= -48, -52, -23, -33, -1, -11, 25, -74, 36, -52, -50, 31, -6, -16, 47, -17, -10, -64, -32, 2; D=-8; /I: I=-8; DM=-21; /M: SY='R'; M= -13, -51, -5, -15, -82, -1, -8, -66, 29, -84,-116, 14, 43, 22, 48, 5, -25, -96, -46, -18; D=-8; /I: I=-8; DM=-21; /M: SY='N'; M= -40, -32, 4, -33, -1, -11, 14, -26, 34, -24, -32, 40, 31, 13, 13, 13, -30, -56, -65, 22; /I: I=-45; MD=-115; /M: SY='P'; M= -28, -54, -35, -45, 25, -14, -29, 14, -1, -7, 23, 10, 35, -9, 16, 2, 7, -8,-120, -10; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='F'; M= -63, -15, -73, -23, 87, -47, -40, -35, -51, -38, 6,-116, 60, -70, -80, -82, 16, -44, -47, 54; /M: SY='K'; M= -42, -45, 14, 2, -74, -47, 6, -56, 46, -84,-112, 40, 33, 20, 10, 25, 17, -47, -42, -15; /M: SY='A'; M= 73, 14,-120,-114, -9, -47, -39, 3,-113, -41, 60,-112, -51, -42,-116, -22, -11, 18, -48, -6; /M: SY='E'; M= -46, -53, 20, 50, -15, -74, 30, -19, 9, -8, 5, -8,-114, 12, -6, 10, 24, -47,-121, 26; /M: SY='F'; M= -96, -58, -81,-128, 116, -85,-114, -34,-124, 3, -66,-123,-131, -74,-122,-119, -31, -37, -9, 21; /M: SY='I'; M= -39, -2, -64, -68, 31, -83, 34, 61, -49, 12, -4, -35, -93, -35, -49, -72, -16, 43,-117, 16; /M: SY='Q'; M= 18, 23, -42, 8,-117,-115, 51, -42, -5, -35,-103, 30, -51, 58, -21, -61, 14, 40, -41,-110; /M: SY='A'; M= 58, 4, -74, -74, -49, 47, -5, -77, -20, 5, -3, -66, -79, 4, -33, -23, -1, -26,-123, -44; /M: SY='D'; M= -55, -60, 115, -60, -92, -43,-101,-130, -76,-130,-127, 41,-115,-102, -78, -18, -45, -86,-146, -84; /M: SY='C'; M= 19, 96, -77, -88, 23, -15,-118, 12, -68, 20, 1,-113, 2, -60,-120, 17, -12, -23,-123, -56; /I: I=-42; MD=-106; /M: SY='F'; M= -13, 31, -78, -40, 67, 20, -47, -72, -37, -19, -27, -24,-121, -49, -2, 28, 30, -88, 4, 21; D=-42; /I: I=-42; MI=-106; MD=-106; IM=-106; DM=-106; /M: SY='S'; M= -3, -20, 23, 2, -37, 16, -6, -89, 33, -34, -28, 10, -52, -19, -5, 33, 13, -2,-127, -61; D=-42; /I: I=-42; DM=-106; /M: SY='E'; M= -19, -24, 29, 44,-118, -78, -2, -33, -1, -13, -36, 28, 41, -3, -21, 10, 1, 3,-129, -52; /M: SY='S'; M= -11, -37, 23, -6, 15, -68, -43, 23, -9, 8, -60, 19, 14, -24, 2, 36, -28, -37, -24, -17; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='L'; M= -56, -39, 20, 12, 11, -57,-110, 7, -58, 41, -18, 29, -31, -54, -23, 5, 36, -27,-123, -43; /M: SY='Y'; M= -14, -52, -24, -3, -15, 0, -63, 30, 2, 30, -14, -22, -35, -47, -6, -2, -22, 2, -9, 33; /I: I=-5; MD=-14; /M: SY='D'; M= -41,-133, 53, 47, -64, -65, -71, -61, -14,-104,-125, 4, -48, 39, -66, 12, 3, -53,-141,-125; D=-5; /I: I=-5; MI=0; MD=-14; IM=0; DM=-14; /M: SY='V'; M= -65, -38, -57, -42, -20, -44, -3, -25, -57, -15, -49, -21, -31, -29, -24, -20, -97, 5,-151, -31; D=-5; /I: I=-5; DM=-14; /M: SY='K'; M= -57,-145, -52, -24, 13, -42, -4, -13, 15, -38,-126, -36, -39, -84, -12, -43, -13, -22, -51, 3; D=-5; /I: I=-5; DM=-14; /M: SY='R'; M= -32, -78, -3, -21, -22, -22, -22, -7, -2, -12, -40, -5, -13, -41, 6, -22, -88, -26,-142, -56; D=-5; /I: I=-5; DM=-14; /M: SY='K'; M= -41, -45, -23, -19, -25, -55, -36, -15, 38, -38, -62, 27, 27, 5, -5, -16, -34, -48,-134, -17; D=-5; /I: I=-5; DM=-14; /M: SY='Y'; M= -43, -65, -16, -40, 13, -36, -6, -8, -4, -15, -32, -12, 11, 0, -12, 8, -14, -22, -28, 51; D=-5; /I: I=-5; DM=-14; /M: SY='G'; M= -50, -70, -50, -15, 19, 28, -1, -21, 4, -6,-111, 11, 1, 9, -20, -5, -16, -11, -26, -44; D=-5; /I: I=-5; DM=-14; /M: SY='D'; M= -40, -35, 35, -22, -15, -53, -30, 1, 9, -7, -45, 13, 25, -41, -16, 12, -9, -11, -32, -27; D=-5; /I: I=-5; DM=-14; /M: SY='K'; M= -7, -3, -9, -27, -16, 19, -11, -59, 39, -19, -50, 4, 33, -2, -18, 2, -20, -62, -13, -32; D=-5; /I: I=-5; DM=-14; /M: SY='N'; M= -14, -10, 18, 17, -12, 10, -8, -91, 30, -48, -30, 30, 16, 5, 5, 26, -15, -34,-125, -32; /M: SY='N'; M= -29,-122, 10, 9, -16, 18, -19, 12, 23, -26, 25, 28, 3, 4, 20, -28, 3, -46, -33, -32; /M: SY='K'; M= -34,-123, -54, -13, -45, 31,-108, -23, 40, -6, 7, -26, 24, 36, 17, -10, 16, -51, -22, -16; /M: SY='F'; M= -18, -5,-131,-128, 115,-127,-112, -55,-123, -38, -66,-123,-131,-129,-121,-117, -78, -4, -35, 47; /M: SY='D'; M=-112,-125, 113, -39,-132, -74, 28,-131,-101,-129,-125, 29,-114, -18, -84, 1, -28,-128,-146,-115; /M: SY='V'; M= -4, -14,-124, -76, -43, -76, -15, 60,-117, 19, -41, -17,-123,-117, -26, -44, -7, 64,-126, -53; /M: SY='V'; M= -8, 36,-127,-123, -38, -54,-128, 56, -77, -76, -92,-120,-123,-121,-123, -14, -31, 84,-129, -66; /M: SY='S'; M= -52, 22, -10,-106, -36, -73,-108, -21,-106,-118, -69, 29, -71,-101,-111, 99, 8, -25,-131,-113; /M: SY='C'; M= -30, 133,-126,-124, -55,-122,-121, 27,-120, -38, 69, -46,-129,-121, -83, 0,-106, -52, 34, -67; /M: SY='Q'; M=-108,-128,-103, -71, -5, -87, 24,-115, -92, -59, 54, 17,-116, 126, -93, -50,-108,-118,-120,-104; /M: SY='F'; M= -83,-119, -56,-126, 119, -73,-113, -96,-122, -3, 15, -23,-131, -42, -57, -76,-113, -79, -93, -45; /M: SY='A'; M= 82, 61, -69,-109, -47, -22, 8,-113,-110,-115, -13,-105,-116,-107, -64, 45, -47, -37,-127,-115; /M: SY='M'; M= -47, -68,-132,-126, 47,-131,-119, 62,-123, 54, 69, -79,-126,-120,-123,-120,-108, 6,-115, -95; /M: SY='H'; M=-115,-128,-100, -99,-117, -87, 151,-131,-103,-116,-102, -13,-117, 31, -72, -75,-114, -85,-147, -87; /M: SY='Y'; M=-118, -48, -58, -82, -12,-125, -45, -72,-112, -50, -55, -35,-130,-108, -74, -76,-112, -83, -78, 137; /M: SY='M'; M= 47, 52,-119, -82, 54, -22, -55, -69,-114, -3, 64, -74, -36, -56,-116, 41, -83, -52,-115, -11; /M: SY='F'; M= -74, 48,-133,-128, 114, -94, -56, -46,-124, 4, 12, -79,-132,-130, -81,-120, -70, -81, 52, -74; /I: I=-31; MD=-79; /M: SY='E'; M= -10, -16, 1, 78,-126, -9, -42, -80, 26, -79,-116, -36,-111, 25, -20, 20, -44, -52,-127, -27; D=-31; /I: I=-31; MD=-79; /M: SY='S'; M= -66, -67,-122,-123,-138,-121,-127,-135, -25,-138, -63,-111, -76,-117,-125, 80, 49,-127,-149,-132; D=-31; /I: I=-31; MI=0; MD=-79; IM=0; DM=-79; /M: SY='E'; M= -37,-126, 3, 81, -51,-119, -9, -17, 17, -23, -46, -25, 20, 25, -14, -31, -40, -34,-124, -8; /M: SY='E'; M= -7,-123, 43, 61, -63,-101, -75, -31, 13, -35, -19, 3, -16, 43, 6, -4, -11, -42,-127, -51; /M: SY='Q'; M= -6, -38, -48, -62, -74, -91, 35, -46, 34, -86, -27, -20,-114, 54, 36, 44, 46, -26,-127, -75; /I: I=-42; MD=-106; /M: SY='A'; M= 66, -30,-125, -81, 14, -82,-121, 15, -80, 29, -3,-120,-122,-115,-120, -47,-106, 22, 59, -52; D=-42; /I: I=-42; MD=-106; /M: SY='R'; M= -46, -69, 22, 36,-122,-116, 31, -63, 1, -65, -20, 33,-117, -16, 74, 13, -25, -76, -38, -41; D=-42; /I: I=-42; MI=-106; IM=-106; DM=-106; /M: SY='N'; M= -21, 20, -58, -14, -52, -22, -38, -45, -20, -30, 34, 75,-117, 39, 23, -20, 43, -59,-129, -46; /M: SY='M'; M= -26, -84, -82,-124, 87,-127,-113, 1,-121, 27, 93,-121,-126,-120,-120, -69, -27, 4, -54, -60; /M: SY='L'; M= -32, 31, -83,-121, 29, -92,-117, 30, -25, 69, 43,-123,-127, -23,-118,-118, -63, -6, -36, -99; /M: SY='R'; M= -23, -54, 7, 28, -90, -57, 19, -88, 45, -69, -34, 6,-114, 28, 56, 14, 7, -77, -54, -1; /I: I=-33; MD=-84; /M: SY='N'; M= -36, -59, -45,-108, -49,-104, -37, -27, -66, -51,-114, 119,-122,-102, -54, -42, 2, -52, -34, -73; D=-33; /I: I=-33; MD=-84; /M: SY='V'; M= 21, 19,-131,-125,-103,-128,-130, 51,-123, 9, -33,-125,-126,-123,-125, -92,-104, 78,-130,-110; D=-33; /I: I=-33; MI=-84; MD=-84; IM=-84; DM=-84; /M: SY='S'; M= 39, 21, -25, -43, -66, -72, -8, -87, 5, -84,-114, 19,-116, -70, -24, 72, 20, -61,-130, -38; D=-33; /I: I=-33; DM=-84; /M: SY='E'; M= -7, -16, 22, 49,-125, -25, -32,-122, 22, -63, -43, 31, -73, 16, 20, 30, -11, -48,-129, -42; D=-33; /I: I=-33; DM=-84; /M: SY='C'; M= 5, 60,-113, -81, -27,-117, 48, -41, -26, 19, -17, 29,-124, -55, 19, 11, -11, -43, -2, 51; D=-33; /I: I=-33; DM=-84; /M: SY='L'; M= -78, -20,-127, -85, -92,-130,-116, -12,-122, 88, 5, -64,-127,-117,-121, -75, 21, -36,-121,-103; /I: I=-38; MD=-97; /M: SY='K'; M= 9, -43, -51, -28,-124, -88, -9,-121, 82, -58,-111, -6, -95, 2, 57, -29, -29, -39,-125,-113; D=-38; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='P'; M= -36, -33, 16, 8,-123, -77, -59, -20, 21, -51, -18, 5, 94, -83, -44, -21, -4, 4,-129,-119; /M: SY='G'; M= -99,-123, 2, -47,-129, 98, -26,-134, -46,-131, -49, 36,-116, -45,-118, -97, -42, -97,-125,-122; /M: SY='G'; M= -45, 2, -77,-122, -94, 105, -86,-136,-116,-132,-122, -98,-116,-114, -89, -36, -47,-129,-122,-124; /M: SY='Y'; M= -72, -60,-118, -80, 33,-125, 26, 11, -3, -17, 0, -40, -26, -80, 9, -52, -21, 15, -97, 99; /M: SY='F'; M= -48,-118,-133,-129, 116, -94,-117, -6,-125, 4, -35, -79,-131,-131,-123,-120,-112, 4, -95, -52; /M: SY='I'; M= -68, -30,-128, -85, 31,-131,-124, 85, -88, 21, -4, -23,-124,-121,-124, -90, -17, 31, -20, -48; /M: SY='G'; M= 23, -4,-117, -83, -4, 85,-120, 27,-118, -26, -17,-105,-118,-115,-123, -67, -82, -34,-120,-114; /M: SY='T'; M= -78, -16,-107, -80, -68, -88,-116, -5,-107, -52,-104, -97,-109,-110,-115, 2, 114, -21,-133,-112; /M: SY='T'; M= -23, 73,-118, -83, 6, -94, -57, 47,-115, -14, 18,-108,-118,-116,-120, -35, 79, 0,-126, -34; /M: SY='P'; M= -58,-125,-120, -79, 35,-121,-113, 7,-114, -38, 49, -46, 93,-115,-120, -51, -6, 24,-113, 43; /M: SY='D'; M=-111, 38, 106, -69,-128,-108, -54, -91,-102, -88, -70, 68,-117,-102,-110, 3,-101,-125, -16, -58; /M: SY='G'; M= 52, 18, -25, -45,-124, 57, -15, -91, -31, -97,-115, -47, -6, -59, -85, 52, -47, -91, -8,-118; /M: SY='D'; M= -41, -27, 59, 37, -59, -50, 11, -97, 28, -61,-114, 51, -56, 7, 0, 9, -20, -47,-128, 7; /M: SY='R'; M= 6, -52, -39, 34, -20, -80, -50, -61, 32, -3, 2, -50,-116, 6, 34, -6, 24, 12, 15, -16; /M: SY='I'; M=-110,-120,-132, -89, -94,-135,-126, 83,-125, 53, -18,-126,-125,-121,-126,-121,-106, 43,-123,-104; /M: SY='W'; M= -21, -22, -40, -34, 37, -85, -9, 13, -26, 21, 42, -19,-123, -61, 6, -17, -70, 36, 62, 19; /M: SY='K'; M= -9,-123, 38, 33, -90, -35, -24,-106, 42, -98, -47, 23, -58, 25, 39, 22, -23, -87, -1, -12; /M: SY='R'; M= -26, -76, -89, -58, -36, -65, 15, -7, 46, 33, 21, -46,-120, -2, 68, -30, -48, -62, -32, -36; /I: I=-4; MD=-10; /M: SY='L'; M= -19, -58,-132,-126, 28,-131, -77, -10,-125, 72, 24,-128, -74, -72,-124, -60, -68, -7, -16, 25; D=-4; /I: I=-4; MD=-10; /M: SY='K'; M= -20, -62, -1, 3, -78, -18, -29, -94, 39, -75, 7, 16,-125, 35, 32, -24, -13, -70,-135, -60; D=-4; /I: I=-4; MI=0; MD=-10; IM=0; DM=-10; /M: SY='K'; M= -24, -69, -31, 2, -50, -31, -17, -25, 37, -18, -30, 19, -15, -3, -5, -8, -42, -33,-134, -14; D=-4; /I: I=-4; DM=-10; /M: SY='K'; M= -27, -61, -15, 3, -59, -22, -9, -99, 59, -58, -74, 24, -5, -19, 41, 8, -8, -48, -38, -65; D=-4; /I: I=-4; DM=-10; /M: SY='S'; M= -6,-121, 28, 28,-126, -9, -32,-123, 27, -92,-115, 27, -9, 39, 23, 40, 9, -92,-128,-115; /M: SY='T'; M= 8, -30, 6, -18, 6, 25, -78, 0, 12, -40, -36, -19, -33, -44, -29, 25, 37, 1, -39, -17; /M: SY='E'; M= -48,-125, 36, 62, -80, 5, -3, -27, -22, -74, -71, 5, 38, 1, -82, 1, -67, -18,-120, 45; /M: SY='T'; M= -29, -24, -18, 3, -42, 18, -49, 15, -5, -16, -16, -1, -26, -66, -30, 7, 65, -3, -3, -67; /I: I=-10; MD=-26; /M: SY='N'; M= -53,-130, 29, 0, -63, -35, 4, -21, 14, -27, -20, 47, 8, -20, -26, -1, -27, -33, -25, -8; D=-10; /I: I=-10; MI=0; MD=-26; IM=0; DM=-26; /M: SY='E'; M= -37, -45, -11, 39, -46, -41, -72, -30, 20, -57, -66, -17, -58, -3, 13, 32, 16, -18, -69, -34; D=-10; /I: I=-10; DM=-26; /M: SY='F'; M= -63, -37, -12, -3, 81, -29, -33, -33, -5, -31, -26, -4, -52, -57, -35, -11, -31, -30, 50, -6; D=-10; /I: I=-10; DM=-26; /M: SY='G'; M= -56,-128, -16, 29,-133, 80,-116,-136, 0,-134,-125, -19,-118, -52, -23, 12, -56, -98,-129,-126; D=-10; /I: I=-10; DM=-26; /M: SY='N'; M= -69,-120, 9, -15,-126, -45, -25, -70, 6,-129,-118, 111, -71, -35, -25, -17, -13, -94,-139, -70; D=-10; /I: I=-10; DM=-26; /M: SY='S'; M= -36,-124, 35, 36,-125, -8, -67,-125, 44, -93,-118, 8, -4, -17, 1, 44, -3, -74,-128, -11; D=-10; /I: I=-10; DM=-26; /M: SY='I'; M= -69, -10, -61, -76, 3, -74, -12, 54, 2, 8, -9, -49, -72, -7, -46, -39, -17, 52, -18, 4; D=-10; /I: I=-10; DM=-26; /M: SY='Y'; M= -72, 28,-123,-120, 52,-126, -25, 3, -10, -9, 10, -66, -52, -64, -73, -84, -82, -27, 68, 105; /M: SY='S'; M= -53, -29, -84, 3, -7, -47, 19, -35, 42, -15, -45, 10, -69, 20, 8, 55, 26, -73, -40, -30; /M: SY='I'; M= -46, -55,-130,-126, 38, -95,-125, 74,-123, -11, -13, -70, -75,-123,-124, -85, -55, 65, -15, 4; /M: SY='E'; M= -23, -77, 3, 58,-122, -65, -9, -34, 31, -68,-111, -37, -53, 2, 34, 13, 45, -23, -46,-113; /M: SY='F'; M= -70, -76, -50, -53, 93, -72,-114, 36, 34, -11, 5, -62, -34,-115, -28, -68, -61, -41, -15, -1; /M: SY='D'; M= -64, -70, 55, 38, -79, -34, -15, 7, 31, -25, -24, 0, 12, -2, -19, -3, -4, -5,-130,-113; /M: SY='K'; M= -12, 3, 22, 32, -35, -36, -27, -71, 46, -78, -39, 13, -2, 17, -12, 20, -23,-117, 5, 45; /M: SY='D'; M= -30,-124, 64, 40, -74, -53, -51, -33, 45, -29, -32, -8, 24, -31, -9, -3, 0, -63,-130,-115; /I: I=-6; MD=-16; /M: SY='Y'; M= -22, -91, 2, -17, 17, -40, -11, -13, -28, -18, -50, -14, 15, -6, -39, -19, 9, -34, -41, 55; D=-6; /I: I=-6; MD=-16; /M: SY='D'; M= -40, -24, 23, -3, -16, -43,-131, -46, -21, -62, -72, -20, 13, -46, -28, -16, -4, -33, -16, -40; D=-6; /I: I=-6; MI=0; MD=-16; IM=0; DM=-16; /M: SY='D'; M= -27, -77, 26, 15, -28, 10, -59, -41, 23, -49, -45, -7, 10, -18, -38, -6, -19, -99,-137, -54; D=-6; /I: I=-6; DM=-16; /M: SY='D'; M= -20, -79, 47, 29, -15, -38, -47, -41, 21, -37, -66, 15, 1, -5, -31, 3, -36, -36,-131, -15; D=-6; /I: I=-6; DM=-16; /M: SY='N'; M= -27, -57, 15, 4, 18, -16, -39, -2, 8, -14, -33, 21, 14, -24, -18, 1, 12, -37, 15, -77; D=-6; /I: I=-6; DM=-16; /M: SY='P'; M= -47, -39, -7, 2, 26, -11, -24, 8, 1, -17, -18, 10, 38, -10, 8, 6, -37, -23, -63, -26; D=-6; /I: I=-6; DM=-16; /M: SY='P'; M= -41,-126, -20, 4, -20, -29, -52, -17, -20, -6, -28, 14, 69, -32, -43, 21, 13, -19,-129, -39; D=-6; /I: I=-6; DM=-16; /M: SY='P'; M= -20, -23, -19, -10, -56, 23, -54, -14, -37, 11, -33, -79, 55, 4, -48, 17, -1, -19, -40, -26; D=-6; /I: I=-6; DM=-16; /M: SY='F'; M= -58, -8, -67, -54, 89, -84, -36, -39, -31, 0, -64, -12, -80, -73,-120, -41, -14, -9, 42, 51; D=-6; /I: I=-6; DM=-16; /M: SY='G'; M= -14, -64, -54, -70, -75, 95, -55, -75, -36,-102,-122, -66, -43,-115,-123, -30, -37, -78,-126,-125; D=-6; /I: I=-6; DM=-16; /M: SY='H'; M= 16, 22, -14,-110, -27, -54, 37, 19, -27, -1, 1, 29, -85, 34, -51, -21, -18, -14, 31, 31; D=-6; /I: I=-6; DM=-16; /M: SY='K'; M= -3, -30, 6, 24, -92, -11,-107, -56, 67, -65, 3, -66, 6, 33, 26, -19, -36, -44,-125, -69; D=-6; /I: I=-6; DM=-16; /M: SY='Y'; M=-115, -54,-122, -58, 1, -90, -97, 44, -59, -14, -53,-121,-128,-113,-115, -80, -68, 0, 13, 119; /M: SY='H'; M= -28, -3, 38, -28, -17, -22, 69, -34, -11, -38, -14, 27, -52, 9, -12, 10, 22, -37, 26, 30; /M: SY='F'; M= -50, -64,-127,-125, 102, -45, -49, -4, -80, -28, 5, -12,-128,-125,-121, -53, -44, 40,-100, 14; /M: SY='Y'; M= -8,-120, -33, -36, 32, -83, 49, -76, 0, -43, -45, 11, -81, 16, -11, 30, 35, -42, 33, 61; /M: SY='L'; M= -60,-119,-126, -91, -8, -70,-115, -3,-118, 74, 35, -52, -45, 23, -77, -57, -52, 12, 44, -26; /M: SY='E'; M= -22,-123, 30, 54, -37, -28, -14, 9, 6, -30, -4, -5, 8, 28, -2, -8, 4, -48,-125, -33; /M: SY='D'; M= -58, -75, 71, 40, 3, 13, -39,-123, -17, -88, -58, 31, -60, -24, -77, 35, -7, -64, 28,-111; /M: SY='A'; M= 48, -34, -40, -25, 9, -24, -28, 21, -51, -60, -8, 19, -63, -1, -51, 27, -2, 20,-122, -19; /I: I=-45; MD=-115; /M: SY='V'; M= -36,-119, -23, 8, -12, -50, -54, 27, -30, -31, 33, 22, -85, -29,-116, -33, -32, 72,-128, -68; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='D'; M= -54,-124, 76, 49,-128, 10, -50, -60, -4, -94, -81, 52, -51, 17, -37, -25, -2, -92,-134,-117; /I: I=-21; MI=0; MD=-53; IM=0; DM=-53; /M: SY='Y'; M= -46,-135, 38, -2, -14, -17, -25, -78, -86,-102, -14, 21, 5, -59, -63, -4, -14, -18,-127, 54; D=-21; /I: I=-21; DM=-53; /M: SY='C'; M= -11, 102,-122, -32, 25, -96, -63, 12, -78, -20, 33, -39,-126, 3, -74, -6, -25, 29,-123, 12; D=-21; /I: I=-21; DM=-53; /M: SY='P'; M= -36, -59, 8, 28,-123, -80, -45, -18, -7,-119, -43, -15, 93, -74, 3, -38, 39, -37,-128, -46; /M: SY='E'; M=-107,-129, -57, 117,-131,-123, -22,-132, -74,-124,-120,-103,-103, 1, -98, -56,-108,-124,-128,-120; /M: SY='Y'; M=-118, 1,-120, -67, 60,-124, -63,-104,-115, -69, -63, -45, -79, -64,-113, -34,-112, -79, 53, 125; /I: I=-45; MI=0; MD=-115; IM=0; DM=-115; /M: SY='L'; M=-111,-117, -90,-123, -7,-131,-118, 2,-123, 81, 0, -64, -75, -66,-122, -50, -73, 38,-120,-101; /M: SY='V'; M= -46, -71,-129,-124, -42,-130,-128, 32,-122, -28, -38,-124, -73,-123,-123, -85, -44, 98,-128, -5; /M: SY='H'; M=-113,-126, 40, -37, -18,-113, 82, -67, -38, -68,-110, 61, 69, -10, -47, -42, -19, -59,-124, 38; /M: SY='W'; M=-117,-125, -73, -87, 86,-125, -68, 1, -3, -23, 5, -57, 27, -39, -15, -61, -30, -28, 101, 30; /M: SY='P'; M= -27, -74, 51, 50, -60, -61, -57, -81, 24,-125, -70, 22, 67, 6, -24, -3, -19, -80,-130,-118; /I: I=-38; MD=-97; /M: SY='Y'; M= -9, -75, -29, -14, 30,-132, -30, -71, -38, -16, -55, -24, -72, -37, -67, 0, 10, -14, -29, 48; D=-38; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='F'; M= -20, -73, -24, -78, 66,-103,-115, 12, -62, 59, 15, -72,-126, -85,-120, -59, -4, 7,-111, -7; /M: SY='F'; M= -58, -20, -46, 23, 48,-127,-117, 47, -20, 20, -10, -30,-121, -81, -67,-111, 19, 38, -56, -39; /M: SY='R'; M= -33, -66, 7, 47, -96,-116, -32, -99, 58,-123,-114, 16,-113, 33, 60, -1, -24, -74,-126, -75; /M: SY='L'; M= 11, -42, -17, 23, -28, -47, -51, 27, 5, 34, 20, -53,-118, -6, -33, 3, 1, 4,-124,-108; /M: SY='M'; M= 39, 43,-127, -93, 37,-120,-115, 8,-118, 50, 79,-120, -72,-115, -66, -59,-107, -36,-116, -48; /I: I=-24; MD=-60; /M: SY='A'; M= 51, 24, -64, -3,-140, -54, -60, -75, 10, -62, 0, -65, -90, -53, -14, -46, -89, -92,-144, -81; D=-24; /I: I=-24; MI=0; MD=-60; IM=0; DM=-60; /M: SY='E'; M= 0, -53, 20, 66, -72, -80, -19, -61, 48, -38, -75, -1,-111, -1, 10, 7, -18, -56,-126, -36; /M: SY='E'; M= -21,-125, 26, 66, -57, -75, 22,-125, 57, -72,-114, 19,-111, 27, 4, -11, -72, -96,-125, -25; /I: I=-38; MD=-97; /M: SY='Y'; M= -22, 54, -92, -95, 26, -55, 44, -40, -95, -23, -13, -30,-135, -71, -77, -83,-117, -21, -60, 99; D=-38; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='G'; M=-102, -66, 24, -83, -35, 86, 9,-130, -32, -84, -55, 54, -78, -14, -45, -45, -79,-127,-126, -61; /M: SY='L'; M=-115, 0, -85, -90, 64,-131,-115, -11, -94, 74, 48, -89, -81, -78,-121, -79,-110, -22, -35, -38; /M: SY='E'; M= -91, -64, 12, 77, -81,-120, -18, -42, 41, -63, -61, -23, -27, -1, 23, -21, 1, -3,-126, -30; /M: SY='L'; M= -78, 20, -87, -51, -43,-130,-115, 11, -53, 80, -8,-125, 3, -65, -48, -71, -81, -6,-118, -3; /M: SY='V'; M= -42,-118, -16, -11,-104, -57, -19, 41, -12, 2, 19, -61,-121, -1, -35, -33, -36, 72,-127, -42; /M: SY='Y'; M= -49, -67, 36, 53, 3, -53, -8, -82, -28, -5, 12, -30, -78, 0, -19, 19, -10, -51, 21, 58; /M: SY='T'; M= -43, -51, -20, -4, -21, -64, 32, -17, 39, -24, -61, 18, -12, 6, 16, 21, 40, -35, 8, 10; /M: SY='K'; M= -16, -80, 32, 28, -32, -43, -60, -38, 52, -21, 14, -7, -31, 31, 11, 4, -15, -39, 0, -40; /M: SY='N'; M= -70,-120, 28, 14, -89, -14, -36, -85, -41, -4, -4, 66, 26,-100, 16, 31, 26, -65,-131, -58; /M: SY='F'; M= -32, -2,-131, -94, 114, -81,-114, -73, -70, 11, 7, -80, -63, -83,-121, -59, -58, -59, -33, -25; /M: SY='H'; M= -3,-122, 18, 23, -59, -32, 69, -5, -6, -12, -29, -12, 15, 11, -25, 15, 3, -18, -28, -8; /M: SY='E'; M= -50, -61, 64, 74, -63, -51, -12,-127, -3,-100, -56, 47, -73, 10, -54, 1, -15,-122,-132, -59; /M: SY='F'; M= -24, -67, -82,-120, 81, -64, -43, 25, -26, 17, 23, -25, -86, -1, -85, -86, -51, 7, 21, 42; /M: SY='Y'; M= -51,-123,-123, -79, 70, -14, -29, 12, -48, 4, -38, -40, -17,-116, -50, -88, -83, -9, 53, 89; /M: SY='N'; M= -3, -65, 39, 48, -41, -55, 6, -34, 12, -15, -32, 50, -5, -6, -26, -15, -22, -38, -58, -2; /M: SY='E'; M= -32,-123, 37, 50, -35, -66, -15, 10, 8, -23, -9, 10, -2, 12, 6, 13, -7, -62,-124, -1; /M: SY='H'; M= -21, -49, -30, 36, 26, -52, 63,-116, -27, -55, 0, 57, -50, 9, 9, -1, -54, -80, -30, 53; /M: SY='K'; M= -26, -2, -23, -32, -51, -27, -8, -9, 51, -29, -15, -1, -38, 0, 42, 38, -12, -21,-123, -8; /M: SY='N'; M= -4, -71, 23, 17, -59, -20, -13, 0, 29, -30, -45, 34, 14, 5, 23, -4, 9, -50,-126, -32; /M: SY='Y'; M= -38, -78, 23, 8, 26, 3, 16, -27, 9, -27, -66, 15, -12, 13, -9, 11, 15, -46, 20, 30; /I: I=-5; MD=-13; /M: SY='F'; M= -55,-130, 13, -12, 43, -25, 13, -76, -11, -27, -4, 13, 40, -60, -10, 7, -36, -44, -12, 9; D=-5; /I: I=-5; MD=-13; /M: SY='E'; M= -28,-132, 13, 38, 10, -30, -11, -56, 23, -64, -30, -1, -13, -14, -12, 3, -12, -56, -48, -26; D=-5; /I: I=-5; MD=-13; /M: SY='N'; M= -61,-135, 15, 3, -17, 4, 10,-100, -6, -33, -15, 43, -53, -30, -43, 3, -52, -85, -37, 12; D=-5; /I: I=-5; MD=-13; /M: SY='L'; M= -15, -70, -31, -20, -20, -6, -72, -23, -14, 3, -30, -37, -66, -8, -1, -23, -31, -8,-138, -20; D=-5; /I: I=-5; MD=-13; /M: SY='M'; M= -20, -59, -47, -36, -4, -50, -57, -9, -16, -3, -2, -25, -32, -34, -57, -11, -68, -51,-142, -11; D=-5; /I: I=-5; MI=0; MD=-13; IM=0; DM=-13; /M: SY='E'; M= -15, -47, -22, 4, -7, -68, -1, -37, -67, -25, -41, -10, -12, -52, -11, -32, -17, -41,-147, -36; D=-5; /I: I=-5; DM=-13; /M: SY='R'; M= -25,-143, -44, -28, -40, -51, -25, -32, 5, -8, 11, -14, -47, -29, 25, -29, -35, -60, -58, -21; D=-5; /I: I=-5; DM=-13; /M: SY='Q'; M= -28, -59, -11, -1, -27, -28, -35, -46, 1, -20, -13, 11, -21, 11, -18, -28, -50, -47, -67, -46; D=-5; /I: I=-5; DM=-13; /M: SY='R'; M= -78,-139, -63, -17, 7, -38, -87, -68, -12, 13, 0, -5,-138, -6, 16, 4, -52, -55, -36, 2; D=-5; /I: I=-5; DM=-13; /M: SY='M'; M= -38,-137, -36, -34, 9, -58, -28, -25, -17, 14, 19, -31, -47, -5, -22, -33, -6, -32,-132, 15; D=-5; /I: I=-5; DM=-13; /M: SY='M'; M= -35,-138, -6, -5, -17, -6, -8, -45, 12, -58, 29, -1, -37, 12, 11, -16, -38, -45,-139, -74; D=-5; /I: I=-5; DM=-13; /M: SY='R'; M= -21, -71, -25, -13, -87, -29, -20, -44, 22, -43, 2, 3, -47, -6, 25, -14, 5, -18, -20, -60; D=-5; /I: I=-5; DM=-13; /M: SY='M'; M= -45, -43, -34, -64, 3, -27, 4, -36, -19, 17, 54, -19, -44, -21, -12, -35, -63, -3, -21, -3; D=-5; /I: I=-5; DM=-13; /M: SY='W'; M= -68, -61, -4, -4, -15, -10, -1, -37, 17, -49, -26, 22, -34, -9, 11, -15, -21, -23, 31, -15; D=-5; /I: I=-5; DM=-13; /M: SY='R'; M= -42, -77, 6, 12, -14, -10, -11, -73, 22, -69,-120, 18, -57, -19, 24, -5, -12, 1, -56, -30; D=-5; /I: I=-5; DM=-13; /M: SY='Y'; M= -13, -56, 5, -56, 1, -13, -2, -30, -11, -26, -20, -1, 8, -28, 4, 15, -18, -38,-126, 33; D=-5; /I: I=-5; DM=-13; /M: SY='M'; M= -40,-131, 25, -5, -8, 14, -15, -32, -24, -13, 45, 26, -45, 1, -10, -68, -40, -32,-131, -4; D=-5; /I: I=-5; DM=-13; /M: SY='R'; M= -30, -28, -19, -32, -48, 23, -9, -84, 31, -32, -69, -11, -19, 5, 32, -9, -24, -17,-131, -21; D=-5; /I: I=-5; DM=-13; /M: SY='D'; M= -32, -26, 27, -7, -43, -22, 17, -39, 12, -26, -38, 25, -19, 20, -43, -30, -13, 5, -28, -17; D=-5; /I: I=-5; DM=-13; /M: SY='G'; M= -21, -60, 10, -9, -22, 40, -74, -51, -12, 5, -17, 7, -1,-113, -36, 3, -17, -61,-128, 1; D=-5; /I: I=-5; DM=-13; /M: SY='T'; M= -34, -75, -23, -1, -51, -40, -17, 6, -3, -19, -14, -23, 5, -14, -7, 1, 54, 23,-131, -57; D=-5; /I: I=-5; DM=-13; /M: SY='M'; M= -54, -58, -86, -30, -51, -17, -63, 18, -7, 53, 66, 3, -32, -37, -43, -30, -16, -12,-125,-108; D=-5; /I: I=-5; DM=-13; /M: SY='S'; M= -51, -65, 15, 8, -53, -16, -45, -73, -28, -61, -13, 41, -10, -33, -4, 71, 39, -71,-130, -73; /M: SY='K'; M= -23,-124, 38, 40, -61, -25, -45, -32, 48, -48, 6, 7, 21, 34, -13, -2, -7, -94,-126, -75; /I: I=-31; MI=0; MD=-79; IM=0; DM=-79; /M: SY='D'; M= 13, -53, 61, 60, -42, -66, -46, -80, -16,-102, -22, -7, -8, 8, -15, 25, -41, -56,-127, -3; /M: SY='E'; M= -40, -29, 17, 87, -41,-118, 3, -55, -53, -11, 16, -53, -80, 48, -73, 7, -52, -77,-125, -25; /M: SY='W'; M= -84,-130, -45, 12, -4, -94, -26, -29, 40, -30, 29, -33, -81, 15, 14, -21, -83, -54, 134, 13; /M: SY='E'; M= -34,-125, 38, 88, -88, -97, -47, -84, 14, -83,-116, -28, -24, 28, -12, -26, 7, -72, -43,-116; /M: SY='I'; M= 47, -48, -74, -43, -11, -83, -55, 49, -69, 7, 9, -75,-121,-115,-119, -87, -21, 45, 39, 8; /M: SY='S'; M= 43, 15, -63, -85, 6, -87,-116, 21, -44, 11, -12, -65, -85, -71, -39, 51, 14, 12,-123,-107; /M: SY='S'; M= -47, -38, 5, -7, 43, 28, 6, -81, -12, -92, -64, -7, -87, -25, 7, 62, 11, -87, -46, -10; /M: SY='L'; M= -67, -36, -96,-122, 26, -57,-114, 21, -71, 75, 31, -78, -78, -63, -36, -36, -56, -27, -55, 6; /M: SY='Y'; M=-117, -50,-112, -61, 20,-121, 2, -92, -60, -65, -33, 44,-128,-107, -57,-110, -85,-110, -34, 128; /M: SY='R'; M= -31, 20, -22, -56, -23, -45, 3, 5, 9, 7, 27, 4, -55, -1, 56, 4, 6, 9,-125,-107; /M: SY='Y'; M= 44, -18, -82, -56, -9, -39,-111, 9, -45, -40, -58, -14,-119, -43,-115, -19, 35, 39, 19, 61; /M: SY='F'; M= -66, -19,-128,-125, 105,-127,-111, -11, -79, -1, 19, -41, -93, -46, -62, -40, -46, -11, -95, 46; /M: SY='V'; M= 48, 51, -40, -26, -81, -79, -41, 32, -31, -53, -28, -26, -66,-113, -61, -17, -58, 63,-129, -77; /M: SY='F'; M= -94, -57,-130, -63, 117, -47, -59, -57, -54, -6, -8,-122, -77, -74,-120, -71, -89, -52, -92, 21; /M: SY='Q'; M= -61, -44, -56, 35,-119, -96, -31, -26, 54, -76, -50, -52, -67, 62, 55, -34, 5, -10, -55, 0; /M: SY='K'; M= -89, -73, -34, -78, -41,-117, -55, -80, 104,-102, -26, -18, -25, -90, 28, -35, -63,-120,-119, -18; /M: SY='R'; M= -16, -83, -31, 10, -65, -50, -23, 26, 20, -11, 27, -13, 0, -19, 35, -18, 2, 31,-125, -35; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 55 in 55 different sequences |
| Number of true positive hits | 55 in 55 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | mRNA cap 0 methyltransferase |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
55 sequences
MCEL_CAMPM (Q8V2R8), MCEL_CAMPS (Q775U0), MCEL_CWPXB (Q8QMV9), MCEL_CWPXG (Q80DX6), MCEL_FOWPN (Q9J584), MCEL_MONPV (A0A7H0DN85), MCEL_RFVKA (P25950), MCEL_VACCA (O57209), MCEL_VACCC (P20979), MCEL_VACCT (Q9JFA8), MCEL_VACCW (P04298), MCEL_VAR67 (P0DSX5), MCEL_VARV (P0DSX6), MCES1_ARATH (Q9LHQ7), MCES1_ORYSJ (Q6Z9U7), MCES2_ARATH (Q5HZ60), MCES2_ORYSJ (Q6K833), MCES_ASPCL (A1CT57), MCES_ASPFU (Q4WN42), MCES_ASPNC (A2QVS9), MCES_ASPOR (Q2UM19), MCES_CAEBR (Q61E36), MCES_CAEEL (Q9XVS1), MCES_CANAL (Q5ADX5), MCES_CANGA (Q6FML4), MCES_CRYNB (P0CO65), MCES_CRYNJ (P0CO64), MCES_DANRE (Q1MTD3), MCES_DEBHA (Q6BMH4), MCES_DROME (Q9VJQ4), MCES_ENCCU (Q8SR66), MCES_EREGS (Q754U7), MCES_HUMAN (O43148), MCES_KLULA (Q6CKI0), MCES_LODEL (A5E032), MCES_MACFA (Q4R7K1), MCES_MOUSE (Q9D0L8), MCES_NEOFI (A1DMG9), MCES_PICGU (A5DDJ4), MCES_PICST (A3GEV2), MCES_PYRO7 (A4R8D7), MCES_RAT(Q5U2U7), MCES_SCHPO (O74880), MCES_XENLA (Q9I8S2), MCES_XENTR (Q28FT4), MCES_YARLI (Q6CC11), MCES_YEAST (P32783), MCE_ASFB7 (P32094), MCE_ASFK5 (P0C995), MCE_ASFM2 (Q65216), MCE_ASFP4 (P0C993), MCE_ASFWA (P0C994), MCE_MIMIV (Q5UQX1), R1AB_WBV24 (Q008X6), R1A_WBV24 (Q008X5)» more
|
| PDB [Detailed view] |
29 PDB
1RI1; 1RI2; 1RI3; 1RI4; 1RI5; 1Z3C; 2HV9; 2VDW; 3BGV; 3EPP; 4CKB; 4CKC; 4CKE; 5E8J; 5E9J; 5E9W; 6RIE; 7D8U; 7Z05; 7Z2J; 8P0J; 8P0K; 8P0N; 8Q69; 8Q8G; 8Q9W; 8RQK; 8Y2Z; 8ZE4 » more |