PROSITE logo

PROSITE entry PS51640


View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] MRG
Accession [info] PS51640
Entry type [info] MATRIX
Date [info] 01-FEB-2012 CREATED;
10-MAY-2017 DATA UPDATE;
27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51640
Associated ProRule [info] PRU00972

Name and characterization of the entry

Description [info] MRG domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=179;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=174;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.8499256; R2=0.0083310; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=22410.0761719; R2=10.1538458; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=919; H_SCORE=31741; N_SCORE=9.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=559; H_SCORE=28086; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-25; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='P';  M= -14, -29,   7,  -9,   0, -33,  -3,  -5,   9,  -6,  15, -26,  33,  14,  12,  17,  -5, -17, -75,  18;
/M: SY='E';  M=   1, -79,  11,  37, -50,   2, -26, -77,  27, -38,  -7,  25,  31,  -7,  29,   1,  -4, -74, -83, -71;
/M: SY='P';  M= -19,  -6,  19,  -6,  -8, -40, -24,   1,  14, -43, -10,  -1,  61,  40,  10, -40, -30,   4, -80, -36;
/M: SY='E';  M= -17, -19,  -2,  37, -75,   1,   9, -75,  12, -64, -38, -18,   3,  -4,  35,  19,  36, -35, -80,   6;
/M: SY='I';  M= -63, -76, -73,   4,  10, -17, -73,  51, -27,  17,  20, -36, -28,   0, -72,   2,  19,  27, -77, -34;
/M: SY='K';  M= -14, -78, -20,  27, -74, -43,  -6, -27,  45, -43,  -4,  10, -20,   6,  39,  17,   3, -16,  17, -29;
/M: SY='I';  M= -66,   5, -85, -38,  35, -88, -80,  66, -49,  29,  -5, -79, -47, -77, -79, -36, -62,  45, -74, -26;
/M: SY='E';  M= -63, -79,  21,  49, -11, -52,  28, -71,  -4, -22, -15,  31,  22,   4,   7,  27, -25, -19, -82, -13;
/M: SY='M';  M= -44, -75, -84, -40,   5, -85, -75,  53, -76,  45,  60, -78, -36, -19, -77, -15, -41,  29,  12, -57;
/M: SY='P';  M= -46, -89, -43, -31, -88, -33, -70, -78, -63, -86, -74, -69, 117, -16, -28,  27, -59, -80, -83, -83;
/M: SY='P';  M= -14, -79,  39,  23,   7, -41,  16, -26,   6,  -5, -10,  -9,  51,   2, -39,  -8,  -4, -12, -82, -65;
/M: SY='P';  M=   0, -77, -24,  31, -75, -31, -35, -16,  -7, -42, -65,   6,  40,  16,   2,  32,  10,  11,   8, -39;
/M: SY='L';  M= -69, -74, -44, -77, -11, -87, -28,  -5, -78,  81,  26, -81, -18, -40, -77, -52, -17, -13, -76, -57;
/M: SY='K';  M= -31, -80, -63,  -3, -72, -33,  -2,  14,  75, -21, -63, -24, -35, -33,  38,   4, -35, -66,  28, -19;
/M: SY='K';  M= -11, -29,   1,   9, -52, -22, -17, -27,  51, -28, -23, -57,   1,  29,  28,  18,  -6,  -9, -80, -33;
/M: SY='I';  M=  -5,  -2, -78, -48, -30, -59, -73,  59,   3,  14,   5, -33, -40,  12,  -9, -37, -62,  25,  47,  13;
/M: SY='L';  M= -48, -74, -78,  12, -21, -87, -70,  -1, -50,  77,  16, -81, -47, -68, -48, -75, -27,  -7, -74, -13;
/M: SY='V';  M= -17, -74, -36,  20, -65, -19, -11,  13, -14,  -7, -17,  10, -75, -20, -30, -62,  11,  67, -86, -67;
/M: SY='D';  M= -12, -81,  81,  47,   1, -51,  15, -78,  -2, -52,  -8,   8, -70,   4,   0, -60, -62, -45, -86, -28;
/M: SY='D';  M= -36, -11, 108,   5, -88, -18, -59, -36, -59, -84, -82, -11, -70, -23, -67,  -7, -60, -81,-100, -74;
/M: SY='W';  M= -48,  22, -49, -34,   3, -76,  16, -69, -34, -26, -24, -25, -44,   4, -17, -14, -24, -45, 143,  53;
/M: SY='E';  M= -46, -80,  45,  67, -46, -75, -59, -48,  23,   4, -12,   0, -39, -22,  -1, -10, -35, -47, -79,  13;
/M: SY='M';  M= -15, -30,  -2, -22,   7, -77, -63,   2, -45,  38,  71,  24, -47,  14,  -4, -41, -42, -21,   9,  12;
/M: SY='I';  M= -26,  -5, -82, -76, -26, -60, -19,  70, -73,  -6, -19, -75, -23,   8, -19, -24, -59,  59, -82, -62;
/M: SY='T';  M= -27,  27, -59, -19, -73, -30, -11, -15,  21, -30, -63,  50, -71,  25,   4, -14,  65, -23,   1, -68;
/M: SY='K';  M= -42, -81,   3,  16, -77, -29,  29, -52,  58, -30, -65,  19, -43,  34,  50, -39, -42, -23, -81, -27;
/M: SY='Q';  M= -20,   0,  17,  24, -76,  19,  13, -73,  23, -12, -65,  25, -71,  44,  12, -10,  -8, -29, -82, -18;
/I:         I=-15; MD=-38;
/M: SY='K';  M= -42, -12, -11, -15, -85,   1,  -3, -58,  42, -31, -34,  14,  10,  38,  14, -69, -73, -84, -87,  -5; D=-15;
/I:         I=-15; MI=0; MD=-38; IM=0; DM=-38;
/M: SY='K';  M= -46,  32, -65, -26,  -1, -75,   5, -35,  54, -36,  50,   1, -12,  51,  23, -21, -37, -10, -75,   6;
/M: SY='L';  M= -24, -73, -79, -43, -53, -27, -73,  14, -72,  66, -42, -75, -80, -32, -11, -18,  17,  22, -78, -21;
/M: SY='V';  M= -14, -12, -75, -37,  35, -79,  34,  16, -43, -17, -53, -21,  25, -71, -15, -24,  -3,  59, -77,  -2;
/M: SY='P';  M=  -1,  -5,  -5,  -2, -71, -60,  -7,  -4,  37, -13, -26, -15,  47,  41,   8,  -1, -42, -32, -77,  14;
/M: SY='L';  M= -42,  16, -77, -27, -53, -82, -71, -10, -74,  71, -12,  14,  10, -26, -75, -30, -62,  18, -80, -62;
/M: SY='P';  M= -44, -91, -68, -41, -86, -71,  30, -76, -63, -84, -71, -26, 118,  -3, -26, -41, -26, -45, -84, -80;
/M: SY='A';  M=  59,  45, -67, -16, -76, -64,  18, -67, -11, -52, -65, -13,  15, -59,  33,  14, -20,   7, -84, -71;
/M: SY='K';  M= -19, -29, -22,  12, -34,  18, -62, -50,  53, -78, -69, -11,   4,  44,  28,  15,   3, -75, -80, -70;
/M: SY='P';  M= -30, -79, -69, -63, -23, -54,  34, -17,   3, -24,  -3,  -5,  71,  -7,  13, -22,  19,  28, -80,   3;
/M: SY='P';  M= -57, -38, -57, -61, -79, -62, -19, -73, -59, -79, -71,  57,  64, -59, -33,  57,  63, -69, -90, -73;
/M: SY='V';  M= -47, -74, -86, -82, -37, -33, -85,  68, -46, -21,  17, -79, -80, -78, -80, -45, -58,  76, -84, -63;
/M: SY='D';  M=  12, -78,  66,  22, -75, -29, -14,  -8,   1, -34, -20,  -3, -71, -26,  16,  -2,   8, -25, -85,  -8;
/M: SY='E';  M= -25, -78,  54,  54, -34, -70,  -9, -78,   9, -77, -72,   5, -33,  32, -14,   9,  37, -55, -86, -31;
/M: SY='I';  M= -35, -79, -87, -83,  -7, -90, -85,  94, -37,   3, -41, -78, -78, -27, -81, -74, -37,  25, -77, -59;
/M: SY='L';  M= -46,  17, -21, -78, -17, -88, -75,  41, -37,  70,  10, -80, -84, -74, -77, -76, -64,  16, -77, -59;
/M: SY='E';  M=  -8, -78,  43,  52, -79, -69,   2, -78,  34, -45, -70,  34, -68, -11,   5,  10,  11, -54, -85, -17;
/M: SY='D';  M=   0, -78,  66,  31, -83, -67,   1, -80, -17, -48, -72,  22, -69,  45,  16,  24,   2, -76, -89, -70;
/M: SY='Y';  M= -75, -81, -79, -79,  77, -32, -52, -37, -38, -33, -54, -76, -86, -72, -70, -71, -39, -49,   3, 112;
/M: SY='I';  M=  -8,  -1, -73,  -2, -15, -50, -69,  31, -11,  30,  23, -29, -78,  -4,  16, -13, -31,  28, -76,   6;
/I:         I=-11; MD=-27;
/M: SY='E';  M=  -2, -85,  -4,  41, -84, -79,  -1, -41,  37, -31, -71, -37, -75,  16,  32, -11,   3, -29, -89, -75; D=-11;
/I:         I=-11; MD=-27;
/M: SY='H';  M= -15, -87,   8, -18,  12, -82,  63, -79, -43, -43, -72, -66, -83,   0, -15,   4,  33, -49, -82,  41; D=-11;
/I:         I=-11; MD=-27;
/M: SY='I';  M= -18,  11, -92, -63,  11, -59, -85,  33,   5,  -8,  -5, -86, -30,   1, -11, -82, -53, -24, -85,   9; D=-11;
/I:         I=-11; MD=-27;
/M: SY='S';  M=  -2, -22, -18, -10,-102, -14, -92, -57, -28, -53, -95, -43, -11, -16, -56,   8, -32, -96,-107, -24; D=-11;
/I:         I=-11; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='E';  M=  -1, -86,  10,  27, -35, -13, -74, -55,  -1, -11, -73,   7, -13, -12,  -2,  -3, -15, -10, -92, -79; D=-11;
/I:         I=-11; DM=-27;
/M: SY='E';  M=  -9, -80,  43,  56, -84, -40,  -7, -82,  38, -81, -73,  33, -39,  -2,  24,  12, -59, -55, -86, -72;
/M: SY='N';  M= -37, -26, -11,   2, -64, -34, -60,   7, -12,  -7,   4,  42, -46,  34,   8,   5,  34, -16, -13,  30;
/M: SY='R';  M= -54, -80,  -7,  30, -10, -27, -23, -53,  53, -52,  16,  26,   6, -50,  54, -23, -24, -17, -80, -67;
/M: SY='T';  M=  -6, -76,  -2,  27, -76, -50, -61, -53,  33, -42, -23,  31,  -6,   9,  24,  22,  39, -70,  11, -28;
/I:         I=-10; MD=-26;
/M: SY='S';  M= -23, -73, -66, -64,   7, -29,  28,   4,   3, -21, -13, -11,  -8,   0, -28,  53,  48, -13, -82, -63; D=-10;
/I:         I=-10; MD=-26;
/M: SY='E';  M= -64,  -8,  33,  57, -24, -21,  32, -57,  16, -36, -70,  -9, -16,  16,  12,   9,   7, -75, -84, -33; D=-10;
/I:         I=-10; MD=-26;
/M: SY='Q';  M= -22,  -5,  35,  18, -10, -12,  13, -59, -14, -58, -31,  23,  22,  55,  -6,  -1, -20, -35, -84, -30; D=-10;
/I:         I=-10; MD=-26;
/M: SY='S';  M=  23, -77,  14, -39, -32,  13, -69, -28,  -4, -35, -70,   9, -12,   7, -26,  44,   4, -29, -87, -74; D=-10;
/I:         I=-10; MD=-26;
/M: SY='T';  M=  -6, -22, -14,  37, -43, -78, -70, -13, -16, -15,  37, -65, -19, -24,  11,  10,  41,  -6, -88, -72; D=-10;
/I:         I=-10; MD=-26;
/M: SY='N';  M= -21, -24,  12,   1, -74, -49, -70,   9, -32,  -3,   3,  29,  24, -66,   5,   2,  10, -50, -88,  -1; D=-10;
/I:         I=-10; MD=-26;
/M: SY='H';  M=  10, -85,  24,  39, -32, -59,  45, -86, -23, -84, -78,  14, -37,   6,  -9,  12,  -5, -56, -93, -36; D=-10;
/I:         I=-10; MD=-26;
/M: SY='K';  M=  -6, -91,  -6,  -1, -80, -84,  20, -19,  30, -31, -40, -20,   3,  29,  -4, -28, -42, -35, -87,  16; D=-10;
/I:         I=-10; MD=-26;
/M: SY='E';  M= -32, -95,  25,  36, -97, -88, -78, -45,   7, -63, -87,  22, -86, -13, -32, -29,   6, -32,-106, -90; D=-10;
/I:         I=-10; MD=-26;
/M: SY='Y';  M= -34, -98, -15, -29, -52, -95, -23, -47,  -9, -21, -12, -41, -24, -37, -86,   9, -34,   5, -95,  26; D=-10;
/I:         I=-10; MI=0; MD=-26; IM=0; DM=-26;
/M: SY='A';  M=  29, -87, -50, -49, -78, -53, -83,   7, -33,  18, -21, -17, -89,   3, -22,  -2, -49, -13, -94, -80; D=-10;
/I:         I=-10; DM=-26;
/M: SY='L';  M= -33,  32, -91, -85, -25, -91, -81,  -2, -81,  49,  11, -85, -90, -80, -14, -53,  -2,  31,  21,  -6; D=-10;
/I:         I=-10; DM=-26;
/M: SY='K';  M=  12, -77, -17,  30, -36, -58,  13,  20,  43, -12, -26,  26, -33, -21,  22, -12, -14, -41, -81, -66;
/M: SY='E';  M= -19, -29,  10,  86, -28, -39,  50, -48, -32, -31,  -8, -60, -24, -28, -38, -62, -30, -32,  37, -23;
/M: SY='F';  M=   0, -11, -76, -35,  46,  -9, -73,  22, -71, -12,  41, -27, -77, -70, -37,  20,   9,  41, -74, -30;
/M: SY='V';  M=  41,  32, -76, -35, -38, -49, -75,  28, -50,  -8,  44, -17, -28, -69, -74, -21,   9,  46, -83, -66;
/M: SY='D';  M=  32, -77,  41,  -1, -76, -49, -61, -47,  30, -19,   3,  -2, -71,  32,  36,   3, -18, -68, -81, -21;
/M: SY='G';  M= -54, -78, -65, -16, -45,  88, -71, -82, -43, -81,  -9, -25, -71, -65,  -4,  17, -14, -24, -79, -76;
/M: SY='L';  M= -68, -75, -87, -82,   3, -89, -76,  56, -80,  63,  44, -82, -83, -75, -79, -46, -31,  18, -76, -56;
/M: SY='R';  M= -36, -21, -67,   4, -25, -79, -24,  -1,  45,   2,   5, -64, -28,   1,  54, -22, -16,  27, -80, -64;
/M: SY='E';  M=  -6, -19,  36,  50, -40, -47, -24,  11, -42,  -4,   6, -25, -42,  35,   4,   4, -27,  -5, -84, -67;
/M: SY='Y';  M= -48, -81,  12, -72,  31, -45,  -4,  -7, -70, -10, -21, -70, -83, -67, -69, -39,  -9, -38, -43, 113;
/M: SY='F';  M= -43, -75, -88, -42, 120, -85, -71, -53, -80, -46, -55, -79, -88, -89, -78, -41, -70, -38, -46,  -5;
/M: SY='N';  M= -38, -77,  75,   7, -41, -38, -53, -82, -54, -84, -76,  90, -72,  11, -36, -22, -10, -81, -96, -73;
/M: SY='K';  M=  15, -76, -34,  14,  23, -72, -13, -62,  49, -41,   4, -19, -72,  23,  15,  -2,   0,  19, -76, -35;
/M: SY='A';  M=  48,  23,   5, -65, -68, -44, -20,  -1, -35, -23,  40,  11, -72, -63, -69,  18,  42, -14,  -5, -18;
/M: SY='L';  M= -26, -74, -84, -79, -21, -86,   8,  24, -79,  78, -36, -32, -84, -73, -77, -75, -29,  -6, -75, -15;
/M: SY='G';  M= -43, -81,  -9, -24, -80,  75, -28, -23, -41, -61,  -4,   8,  46, -65, -20,   2, -65, -44,  17, -75;
/M: SY='R';  M= -16,  28, -19, -62,  22, -38,  12, -65,  20,   2, -61,  17, -45,  -2,  31,  23,  25, -16, -77,  -1;
/M: SY='Q';  M= -44, -33, -68, -40,  20, -52,  52,  27, -34,  -4,   5,   3, -76,  64,  24,   3, -18,  -2, -77, -24;
/M: SY='L';  M= -70, -73, -88, -80, -45, -90, -72, -19, -80,  90,  -6, -86, -87, -74, -37, -80, -67, -26, -75, -57;
/M: SY='L';  M= -71, -73, -88, -80,  -3, -89, -72, -19, -81,  90, -33, -86, -87, -75, -79, -80, -31, -43, -74, -55;
/M: SY='Y';  M= -74, -36, -31, -74, -14, -80,  -3, -62, -67, -59, -55, -24, -85, -64, -31, -68, -19, -66,  15, 129;
/M: SY='K';  M= -21, -83,   3,   3, -83, -43, -19, -79,  61, -79, -23,   0,  57,   6,  47, -27, -20, -50, -82, -72;
/M: SY='F';  M= -46, -76,  -6,  17,  70, -48,  24, -38, -16, -19, -31, -20, -38,  23, -65,  34,   4, -46, -16,  20;
/M: SY='E';  M= -64, -85, -35, 112, -87, -80, -57, -88, -23, -80, -77, -60, -59, -38, -54, -60, -64, -80, -84, -77;
/M: SY='R';  M= -70, -27, -29,  -4, -75, -80,  -3, -44,  15, -34, -66, -43, -77,  -1, 101, -65, -68, -50,  50, -63;
/I:         I=-3; MI=0; MD=-8; IM=0; DM=-8;
/M: SY='P';  M= -13, -79, -67, -26, -70, -11,  18, -47,  -5,  10,   8, -17,  73,   8, -33,  23,  11, -31, -79,  -3;
/M: SY='Q';  M= -42, -87, -56,  23, -89, -27, -17, -80, -45, -76, -64, -20,  -9, 119, -13, -29, -65, -81, -77, -31;
/M: SY='Y';  M= -36,  -8, -47, -75,  42, -81,  14, -28, -37, -43, -16, -73, -84, -67, -37, -43, -28,   9, -43, 113;
/M: SY='N';  M=  24, -74,   8,  -3, -69, -21, -19,   4,   5, -12,  28,  46, -73,  -4,  -2,  14, -27,  -2, -82, -11;
/M: SY='D';  M=  10, -80,  63,  61, -43, -32, -14, -28,  26, -56, -31,  -9, -14,  -2, -57, -41, -43, -36, -86, -71;
/I:         I=-10; MD=-25;
/M: SY='I';  M= -30, -80, -87, -56, -20, -89, -78,  51, -42,  48,  21, -82, -84,   0, -78, -76, -29,  18,  28,   4; D=-10;
/I:         I=-10; MD=-25;
/M: SY='L';  M= -32,  10, -46, -52, -40, -88, -24,   5, -33,  45,  28, -41, -87, -72,  30, -31, -55,  21, -14, -67; D=-10;
/I:         I=-10; MD=-25;
/M: SY='Q';  M= -51, -92,  -7, -18, -92, -56, -22, -38,  41, -88, -24,   6, -83,  43,  22,   9,  -5, -85, -94, -42; D=-10;
/I:         I=-10; MD=-25;
/M: SY='K';  M= -41, -98,  18,   7, -93, -60, -77, -57,  46, -35, -84, -35, -23,  16,   7, -30, -79, -90, -17, -21; D=-10;
/I:         I=-10; MI=0; MD=-25; IM=0; DM=-25;
/M: SY='P';  M=  10, -94, -56, -44, -82, -33, -88, -46, -59,  11, -74, -46,  35, -85, -37, -27, -12,  -6, -95,  -2; D=-10;
/I:         I=-10; DM=-25;
/M: SY='N';  M=  -3, -92,  13, -28, -39,  15,   1, -45, -76, -88, -12,  24,   7,   1, -44,   7, -50, -22,-100, -85; D=-10;
/I:         I=-10; DM=-25;
/M: SY='H';  M= -40, -89,  27,  25, -31, -25,  53, -27, -38, -41, -35,   6, -21,  -6, -36,   0, -26, -79, -82,  45; D=-10;
/I:         I=-10; DM=-25;
/M: SY='P';  M=  -1, -88, -19,   1,   5, -16, -74, -60, -20, -56, -75, -19,  55,  16, -23,  15, -14, -24, -85, -11; D=-10;
/I:         I=-10; DM=-25;
/M: SY='G';  M= -43, -85,  41,  15, -88,  51,  22, -59, -39, -87, -78,  31,  29,  20, -70, -59,  -7, -85, -89, -48; D=-10;
/I:         I=-10; DM=-25;
/M: SY='F';  M=   8, -77, -40, -11,  61, -77, -69, -45,  42, -38,   4, -38,   1, -62,  27, -24, -18,  17, -71, -54; D=-10;
/I:         I=-10; DM=-25;
/M: SY='R';  M= -64, -32,   7,  11, -76, -31, -11, -76,   2, -18, -39,  13,  49, -16,  62,  25,   1, -74, -82, -22;
/M: SY='P';  M=  32, -79, -42, -65, -15, -71, -69, -16, -42, -21,  66, -73,  84,  -9, -72, -41, -61,   2,   3,  12;
/I:         I=-42; MI=0; MD=-106; IM=0; DM=-106;
/M: SY='S';  M=   6,  41, -64, -29, -30, -44, -66, -69, -62, -23, -67, -54, -71, -14, -30,  90,  -4, -17, -85, -69;
/M: SY='D';  M=  17, -79,  53,  49, -81, -32, -27, -48,  10, -42,  -1, -27, -26,  43, -14,  -1,  -2, -72, -84, -40;
/M: SY='H';  M= -30, -77, -73, -48, -38, -81,  77,  58, -69,  -3, -48,   0, -77,  -8, -16, -42, -11,  42,  -1,  -9;
/M: SY='Y';  M= -74,  -8, -75, -78,  41, -81, -45, -60, -70, -56, -54, -75, -86, -67, -68, -33, -29, -64, -34, 127;
/M: SY='G';  M= -53, -81, -67, -78, -86, 100, -74, -93, -72, -90, -79, -18,   0, -70, -80, -28, -70, -87, -78, -81;
/M: SY='A';  M=  64,  27, -76, -71,   7, -20, -76,  32, -71, -26,   7, -69,  -9, -70, -75, -17,   3,  13, -79, -66;
/M: SY='E';  M= -37, -80, -11,  62, -47, -82, -71,  57, -63, -45,  -4, -68,  38, -17, -70, -65,   6,  25, -83, -69;
/M: SY='H';  M= -73, -84, -58, -59, -25, -75, 145, -40, -63, -70, -57, -14, -23, -53, -57, -63, -71, -84, -98,  -1;
/M: SY='L';  M= -71, -73, -88, -81,  42, -89, -72, -17, -81,  84,  -7, -85, -87, -76, -79, -79, -28, -45, -69, -51;
/M: SY='L';  M=  10, -71, -85, -78, -49, -83, -75, -12, -79,  78, -37, -82, -84, -74, -78, -72, -20,  25, -78, -60;
/M: SY='R';  M= -70, -87, -66, -56, -77, -46, -55, -86, -29, -78, -68, -19, -79, -45, 115, -64, -69, -80, -78, -15;
/M: SY='M';  M= -69, -73, -87, -79,  13, -86, -68, -28, -78,  74,  82, -82, -25, -72, -76, -77, -27, -14, -73, -20;
/M: SY='F';  M= -73, -76, -89, -84,  85, -43, -74,  41, -81,  50, -13, -82, -26, -81, -80, -78, -67, -34, -60, -15;
/M: SY='V';  M=  -2, -69, -74, -71, -63, -72, -76, -19, -70, -24, -54, -30, -20, -69, -74,  45,  30,  74, -86, -16;
/M: SY='K';  M= -65, -80, -65, -56, -70, -75, -61,   2,  66, -19, -23,   2, -22,   4,  60,  -1, -18, -10, -76,   2;
/M: SY='L';  M= -43, -74, -87, -79,  35, -87, -71,  14, -79,  77,  41, -82, -85, -20, -77, -77, -27, -44, -71, -52;
/M: SY='P';  M= -66, -89,  -6, -17, -87,  12,  29, -80, -64, -86, -74, -31, 111, -65, -31,  -5, -26, -82, -85, -79;
/M: SY='E';  M=  12, -78,  39,  69, -79, -46, -60, -77,  15, -33, -41,   2, -27,  -6, -58,  10,  10, -55, -83, -18;
/M: SY='M';  M= -53, -19, -31, -42,  13, -83, -69,  12, -38,  57,  68, -76, -81, -39, -31, -16, -43,  15, -73,   5;
/M: SY='L';  M= -67,  -9, -82, -77,  -9, -85, -73,  45, -76,  63,  28, -32, -81,  -1, -76, -23,  12,  -1, -77, -58;
/M: SY='A';  M=  52,  27, -63,   2, -76, -35,   8, -20,  13, -72, -66,   0,   9,  23, -33,  35, -56, -14, -81, -22;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='Q';  M= -16,  24,   2,  16, -67, -30,  37, -15, -18, -19, -10,  11, -77,  45, -65,   3, -26,   3, -78,  41; D=-31;
/I:         I=-31; DM=-79;
/M: SY='T';  M= -27, -25, -65,  -7,  -3, -35, -68, -58, -63, -10,  16, -58,   6, -27, -34,  46,  72,   9, -82, -26;
/M: SY='N';  M= -63, -78,  34,  -3,   5,  -7, -23, -72, -10, -26, -68,  46,  41,  33, -31,  23,  21, -42, -82, -29;
/M: SY='M';  M=   4, -76, -35, -75,   8, -40, -72,  33, -24,  33,  78, -75, -24, -69, -73, -39, -29,  -8,  76,  -3;
/M: SY='D';  M= -44, -78,  76,  17, -83, -42, -10, -31, -30, -81, -31,  58,   2, -27, -32,  34,  -4, -76, -94, -72;
/I:         I=-29; MI=0; MD=-75; IM=0; DM=-75;
/M: SY='P';  M=  -1, -81,  37,  34, -73,  11,  -3, -37, -59, -61, -68,  -7,  45,  36, -42,   5, -13, -23, -77,  33;
/M: SY='Q';  M=  -5, -80,   2,  36, -19,  -9,  38, -43,  24, -72,   1,  27,   4,  42,   8, -16, -61, -13, -80,  -9;
/M: SY='S';  M=   7, -72,  -5, -18, -16, -38, -64, -47,   7, -12,  33,  -2, -33, -57,   4,  57,  31, -17, -81, -17;
/I:         I=-38; MD=-97;
/M: SY='M';  M=  -8,  -5, -82, -27, -64, -42, -79,  36, -36,  28,  38, -77, -25,   8, -77, -23,   0,  21,  23, -67; D=-38;
/I:         I=-38; MI=-97; MD=-97; IM=-97; DM=-97;
/M: SY='N';  M= -23, -81, -38,   8, -46, -49,  26, -50,  40, -51, -34,  47, -42,  19,   0, -16,  18,   4, -90, -72; D=-38;
/I:         I=-38; DM=-97;
/M: SY='R';  M= -25, -82, -22, -12, -40, -41, -69,  21,   9,   9,  -8,  20, -81, -11,  42, -24, -41,  11, -83,  -8; D=-38;
/I:         I=-38; DM=-97;
/M: SY='L';  M= -68, -26, -86, -81, -13, -89, -18,  57, -78,  63,  16, -81, -83, -74, -32, -45, -42,  17, -75, -13;
/M: SY='R';  M=  -8, -26, -68,   5,  -3, -77,  -7, -12,  28,  23,  23, -13, -76,  19,  46, -32, -24,   7,  -8, -61;
/M: SY='E';  M=  11, -77,  11,  34, -75,  -5,  11,  11,  13, -47, -65,  10, -14,   0,  -2,  25,   9, -24, -83, -35;
/M: SY='H';  M= -11, -80, -61,  32, -15,  37,  67, -20,  -2, -40, -64, -59, -25,   7,  -5, -22,  -1, -55,  -2,  44;
/M: SY='L';  M=   2,  11, -83, -79,  16, -82, -76,  46, -77,  50,  28, -31, -25, -74, -78, -24, -42,  24, -76, -58;
/I:         I=-45; MD=-115;
/M: SY='H';  M= -12, -77,  34,   5, -77, -28,  52, -72,  16, -10, -27,  29, -28,  21,  -9,  21,  21, -36, -88, -67; D=-45;
/I:         I=-45; MI=-115; IM=-115; DM=-115;
/M: SY='D';  M=  -8, -20,  65,  40, -79, -45, -61, -17,  21, -22, -29, -20, -26,   3,   6,  25, -59, -53, -87, -71;
/M: SY='F';  M= -72, -28, -88, -83,  89, -86, -73,  14, -80,  51,   1, -81, -86, -80, -44, -24, -66,  -9, -60, -39;
/M: SY='L';  M= -26, -73, -81, -75, -53, -83, -73,  33, -75,  64,  32, -76, -24,  -3, -76, -22,  19,  10, -79, -61;
/M: SY='Q';  M= -25, -79,  30,  39, -78, -23, -19, -30,  34, -18, -29,   6, -70,  41,  25,  13, -16, -34, -83, -69;
/M: SY='W';  M= -75, -83, -85, -79,  85, -52, -11, -31, -44, -24, -58, -78, -85, -19, -42, -21, -72, -65, 110,  75;
/M: SY='L';  M= -51,  -3, -45, -45, -26, -87, -72,  16, -76,  74,  46, -81, -84, -72, -31, -76, -30,   4,  -7, -23;
/I:         I=-36; MD=-90;
/M: SY='Q';  M=  24, -17,   4,  30, -50, -20,  11, -26, -29, -32, -67,  21, -73,  37, -27,   9,  10,  -2, -88, -72; D=-36;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='K';  M= -22, -78,  31,  38, -77, -29, -11, -71,  46, -13, -66,  33, -70,  -6,  28, -31,   2,  -7, -85, -70;
/M: SY='N';  M= -38, -77, -30,  18, -75, -63,  82, -39, -32, -56, -28,  96, -22, -52,   6, -26, -57, -78, -92, -17;
/M: SY='H';  M=  20, -37, -67, -19, -35, -48,  52,  -7,  -5,   7,  36, -26, -45,  50,  10,   5, -62, -13, -74,  28;
/M: SY='D';  M=   1, -77,  47,  35, -78, -18,  32, -44,  29, -44, -70,  15, -20, -22, -25,  34, -18, -49, -85, -18;
/M: SY='K';  M= -13, -77,  15,  28, -13, -47, -62, -56,  46, -57, -68,   1,  -2,  14,  30,   3,  40, -41, -82, -68;
/M: SY='Y';  M= -39,   2, -43, -79,  64, -59, -64, -22, -76,  41,   8, -47, -85, -74, -75, -35, -46, -22,  65,  74;
/M: SY='F';  M= -28,  -3, -84, -80,  97, -32, -66, -40, -76,  12, -53, -77, -86,  -1, -75, -72, -28, -27,  35,  54;
/M: SY='R';  M= -26, -76,  22, -28, -46,  -1, -65, -44,   8,  -8,   3,   9,  -3,   5,  27,  20,  20,  26, -84, -68;
/M: SY='S';  M=  18, -76, -21,  31, -74,  -1, -28, -48,  -2,  -7, -64, -13,   5, -14,  26,  35, -13,  -2,  17, -69;
/M: SY='E';  M=  -5, -77,  29,  36, -79, -28,   3, -38,  19, -55,  -7,   5,  14,  22, -13,  23,  29, -29, -86, -70;
/I:         I=-33; MD=-84;
/M: SY='N';  M=  35, -82,  21,  -8, -14,  -9, -25, -30, -36, -82, -77,  36, -19, -44, -76,  20, -25, -38, -91, -35; D=-33;
/I:         I=-33; MI=0; MD=-84; IM=0; DM=-84;
/M: SY='Y';  M= -74, -85, -36, -33, -12, -81, -12, -60, -22, -31, -19, -73, -84, -16, -40, -69, -69, -43,  24, 126;
/M: SY='E';  M=   4,  -6,  -9,  41, -29, -59,  -5, -13, -12, -13,  17, -12, -26,  11,  34,   3,   6,  10, -83, -66;
/M: SY='P';  M= -18, -77,  37, -18, -75, -40, -65,   5, -39, -28, -33,  35,  55, -14, -28,  35,  21,  -8, -87, -46;
/M: SY='A';  M=  54, -74, -10,  -6, -44, -47, -28, -23, -25, -20, -64,   7,  51,  16, -27, -25,  32, -45, -82, -72;
/M: SY='S';  M= -10, -31, -10,   3, -17, -17, -21, -47,   2, -29, -66, -28,  41,   6, -35,  55,  28, -47, -77,  18;
/I:         I=-42; MI=0; MD=-106; IM=0; DM=-106;
/M: SY='P';  M=  18, -77, -12,  16, -42, -68,  30,  -5, -43, -61, -66,  15,  70, -22, -47,  18,  33, -35, -84, -33;
/M: SY='E';  M=  16, -79,  36,  53, -46, -16, -12, -44, -12, -24, -67, -37,  -7,  37, -24,  10, -34, -18,  -1,  -5;
/M: SY='Y';  M= -69, -82,   5,   3,  10,  -4,  -1,  -1,   4, -25, -25, -66, -24,  -9, -35, -41,  -7, -64,   8,  99;
/M: SY='E';  M= -35,  -4,   1,  54, -12, -13,  49,   5, -20, -20,   0,  -9,  14,  22,  -1, -18, -29, -31, -80, -11;
/M: SY='R';  M=  -7, -27,  -3,   2, -51,   7,  16, -17,  -5, -56, -67,  45,  -6,   1,  57,  -1,  10, -42, -84, -69;
/M: SY='R';  M= -35, -80,  -2,  36, -71, -38,  10, -20,  29,  10, -12,  -2, -21,  23,  39,   6, -62, -19,   2, -27;
/M: SY='W';  M=  35, -75, -29,  18, -24,   9,  -6,  -2,   0, -23, -63, -12,  -1, -60, -42,  20,  11,  -4,  37, -18;
/M: SY='Q';  M= -10,  -4, -34,  -1, -19,  11, -16,  -2,  15,  13,  20, -62,  13,  30,  15,   4,  -1, -32, -12, -65;
/I:         E1=0; IE=-380; DE=-380;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.


Total number of hits 35 in 35 different sequences
Number of true positive hits 34 in 34 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 97.14 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] MRG
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
34 sequences

EAF3_ASPFU  (Q4WPW2), EAF3_CANAL  (Q59K07), EAF3_CANGA  (Q6FN68), 
EAF3_CRYNB  (P0CO87), EAF3_CRYNJ  (P0CO86), EAF3_DEBHA  (Q6BT38), 
EAF3_DICDI  (Q54RM0), EAF3_DROME  (Q9Y0I1), EAF3_EMENI  (Q5BBV4), 
EAF3_EREGS  (Q75AH9), EAF3_KLULA  (Q6CND0), EAF3_SCHPO  (O13953), 
EAF3_USTMA  (Q4P827), EAF3_YARLI  (Q6C9M9), EAF3_YEAST  (Q12432), 
MO4L1_HUMAN (Q9UBU8), MO4L1_MOUSE (P60762), MO4L1_PONAB (Q5NVP9), 
MO4L1_RAT   (Q6AYU1), MO4L2_HUMAN (Q15014), MO4L2_MACFA (Q4R578), 
MO4L2_MOUSE (Q9R0Q4), MO4L2_PANTR (A5A6J5), MO4L2_PONAB (Q5R905), 
MO4L2_RAT   (Q6QI89), MRG1_ARATH  (Q94C32), MRG1_CAEEL  (A7DTF0), 
MRG2_ARATH  (Q4V3E2), MS3L1_HUMAN (Q8N5Y2), MS3L1_MOUSE (Q9WVG9), 
MS3L1_PONAB (Q5R6Y9), MS3L2_HUMAN (P0C860), MSL3_DROME  (P50536), 
MSL3_DROVI  (Q9NBL2)
» more

UniProtKB/Swiss-Prot
False positive sequences
1 sequence

DNLJ_NEIG1  (Q5F9Z9)

		
PDB
[Detailed view]
24 PDB

2AQL; 2F5J; 2LKM; 2N1D; 2Y0N; 6AGO; 6INE; 7S4A; 7YI0; 7YI1; 7YI2; 7YI3; 7YI4; 7YI5; 8BPA; 8C60; 8I02; 8KC7; 8KD2; 8KD3; 8KD4; 8KD5; 8KD6; 8KD7
» more