ProRule PRU00972

General rule information [?]

Accession PRU00972
Dates 5-MAR-2013 (Created)
27-JUN-2022 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51640; MRG
Name MRG domain
Function The ~170 amino acid MRG domain binds a plethora of transcriptional regulators and chromatin-remodeling factors, including the histone deacetylase transriptional corepressor mSin3A and the nuclear protein PAM14 (protein-associated MRG, 14kDa).
Scope(s) Eukaryota
Example(s) Q9WVG9 (MS3L1_MOUSE);

Propagated annotation [?]

Comments [?]


Keywords [?]

Gene Ontology [?]

GO:0006325; Biological process:chromatin organization
GO:0006351; Biological process:DNA-templated transcription
GO:0006355; Biological process:regulation of DNA-templated transcription

Features [?]

From: PS51640
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="MRG #"

Additional information [?]

Size range 154-360 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]