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annotation rule: PRU00972

General rule information [?]

Accession PRU00972
Dates 5-MAR-2013 (Created)
21-NOV-2019 (Last updated, Version 6)
Data class Domain
Predictors PROSITE; PS51640; MRG
Name MRG domain
Function The ~170 amino acid MRG domain binds a plethora of transcriptional regulators and chromatin-remodeling factors, including the histone deacetylase transriptional corepressor mSin3A and the nuclear protein PAM14 (protein-associated MRG, 14kDa).

Propagated annotation [?]

Comments [?]

Subcellular location Nucleus.

Gene Ontology [?]

GO:0006325; Biological process: chromatin organization.
GO:0006351; Biological process: transcription, DNA-templated.
GO:0006355; Biological process: regulation of transcription, DNA-templated.

Keywords [?]

Features [?]

From: PS51640
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       MRG #        

Additional information [?]

Size range 154-360 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q9WVG9 (MS3L1_MOUSE)
Comments None


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]