ProRule PRU00972
General rule information
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| Accession | PRU00972 |
| Dates | 5-MAR-2013 (Created)
27-JUN-2022 (Last updated, Version 7) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51640; MRG |
Name | MRG domain |
| Function | The ~170 amino acid MRG domain binds a plethora of transcriptional regulators and chromatin-remodeling factors, including the histone deacetylase transriptional corepressor mSin3A and the nuclear protein PAM14 (protein-associated MRG, 14kDa). |
| Scope(s) |
Eukaryota |
| Example(s) | Q9WVG9 (MS3L1_MOUSE); |
Propagated annotation
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Comments
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| SUBCELLULAR LOCATION | Nucleus. |
Keywords
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Gene Ontology
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| GO:0006325; Biological process:chromatin organization |
| GO:0006351; Biological process:DNA-templated transcription |
| GO:0006355; Biological process:regulation of DNA-templated transcription |
Features
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| From: PS51640 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="MRG #" | |||||||||
Additional information
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| Size range | 154-360 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [36] All [ 36 ]
- Retrieve set of proteins with 3D structure for this domain