PROSITE logo

PROSITE entry PS51652


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] AV_ZBD
Accession [info] PS51652
Entry type [info] MATRIX
Date [info] 01-AUG-2012 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51652
Associated ProRule [info] PRU00985

Name and characterization of the entry

Description [info] Arteriviridae zinc-binding (AV ZBD) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=67;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=62;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2115955; R2=0.0074997; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=8898.2285156; R2=4.7628765; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=972; H_SCORE=13528; N_SCORE=9.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=572; H_SCORE=11623; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-15; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='G';  M= -56, -80, -67, -68, -87,  71, -72, -90,  43, -89, -80, -55, -73, -62, -64,  68, -60, -83, -84, -79;
/I:         I=-28; MD=-71;
/M: SY='K';  M= -90,-104, -82, -68,-106, -97, -85,-106,  93,-105, -93, -75, -90, -67, -51, -84, -84,-102, -99, -93; D=-28;
/I:         I=-28; MD=-71;
/M: SY='K';  M= -89,-105, -73,  48,-107, -99, -84,-108,  76,-105, -95, -78, -87, -65, -58, -84, -85,-102,-102, -95; D=-28;
/I:         I=-28; MI=-71; IM=-71; DM=-71;
/M: SY='C';  M=  58,  85, -85, -80,  64, -75, -82, -57, -79, -61, -63, -77, -85, -81, -82, -64, -65,  40, -77, -59;
/I:         I=-30; MD=-77;
/M: SY='R';  M= -91,-111, -87, -72,-107,-101, -78,-107, -55,-101, -89, -81, -99,  67,  83, -84, -92,-104,-102, -89; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='H';  M=  -8, -21, -21, -19, -12, -30,  53,  13, -19,  -1,   0, -13, -25, -18, -20,  -9,  20,  41, -44,  -7;
/M: SY='C';  M= -14, 128, -33, -34, -24, -29, -33, -31, -29, -21, -22, -20, -44, -37, -36, -16, -14, -18, -54, -35;
/M: SY='T';  M=  19, -17, -13, -15, -26,  31, -19, -21, -13, -24, -18,  -2, -16, -12, -20,  25,  36, -13, -33, -22;
/M: SY='I';  M= -13, -26, -29, -27,  -6, -36,  44,  45, -25,   8,   7, -20, -27, -21, -25, -20,  -9,  38, -36,  -6;
/M: SY='C';  M= -14, 128, -33, -34, -24, -29, -33, -31, -29, -21, -22, -20, -44, -37, -36, -16, -14, -18, -54, -35;
/M: SY='C';  M=  -8,  64,  33, -13, -34,  55, -20, -39, -19, -34, -28,  -1, -24, -19, -27,  -6, -16, -32, -37, -29;
/M: SY='A';  M=  53, -14, -17, -12, -28,  -1, -19, -19, -14, -21, -15, -10, -18,  -9, -18,  25,   0,  -7, -29, -23;
/M: SY='P';  M=  28, -22, -14,  -6, -29, -13, -19, -21,  22, -24, -16,  -9,  40,  -8,  -5,   1,  22, -13, -30, -23;
/M: SY='P';  M=  35, -23, -17, -10, -31,  -7, -20, -22, -14, -27, -18, -14,  61, -12, -21,  19,  -3, -15, -31, -27;
/M: SY='D';  M= -11, -24,  32,  -6, -20, -26, -17,   2,  -4, -11, -10,  -6, -23, -11,  24,  -8,  20,  26, -41, -17;
/M: SY='Y';  M=  27, -19, -21, -18,   1, -17, -11,  -6, -17,  12,  -2, -16, -24, -15, -19,  -2,  20,  -3, -11,  39;
/M: SY='K';  M=  19, -20, -15,  -7, -22, -18, -20,  -6,  32, -15, -10,  -8, -18,  -6,   1,  -1,  22,  14, -31, -18;
/M: SY='S';  M=   7, -16,  -8,  -9, -27,  -2, -11, -26,  -9, -30, -23,   3, -16,  -1, -14,  61,  12, -19, -35, -19;
/M: SY='A';  M=  43, -16, -20, -15, -18,  -7, -19, -10, -17,  10,  -6, -14, -21, -11, -20,  20,  -3,  -4, -28, -18;
/M: SY='C';  M= -14, 128, -33, -34, -24, -29, -33, -31, -29, -21, -22, -20, -44, -37, -36, -16, -14, -18, -54, -35;
/M: SY='G';  M=  -1, -29, -17, -28, -35,  77, -23, -43, -22, -39, -28,  -3, -21, -20, -30,  -2, -21, -37, -26, -30;
/M: SY='M';  M= -11, -24, -28, -28,  -6,  38, -18,   1, -25,  32,  39, -19, -27, -19, -26, -16, -17,  -4, -25, -12;
/M: SY='W';  M=  11, -31,  33,  -8, -14, -13, -18, -27, -13, -28, -25,  26, -25, -12, -19,  -9, -14, -28, 110,  -2;
/M: SY='F';  M= -22, -22, -38, -31,  53, -37, -21,  10, -31,  45,  13, -34, -37, -29, -28, -29, -17,   3, -10,  10;
/M: SY='C';  M= -14, 128, -33, -34, -24, -29, -33, -31, -29, -21, -22, -20, -44, -37, -36, -16, -14, -18, -54, -35;
/M: SY='D';  M= -12, -29,  49,  -5, -22,  40, -15, -19, -17,   9, -13,  -1, -23, -15, -23, -10, -15, -21, -35, -20;
/M: SY='F';  M= -22, -24, -11, -23,  59, -20,  -3, -11, -15,  -7,  -9,  42, -33, -18, -18, -12, -11, -15,  -2,  42;
/M: SY='C';  M= -17, 105, -19, -19, -22, -27,  75, -34, -20, -21, -14,  -7, -33, -17, -19, -14, -16, -26, -55,  -9;
/M: SY='V';  M=  21, -19, -21, -20, -20,  24, -24,   2, -19, -12, -10, -12, -23, -16, -23,  22,  -2,  27, -33, -20;
/I:         I=-28; MD=-71;
/M: SY='P';  M= -45, -65, -38, -32, -56, -46,  45, -55, -38, -55, -41, -37,  58, -36, -43, -39, -39, -58, -64, -37; D=-28;
/I:         I=-28; MI=-71; MD=-71; IM=-71; DM=-71;
/M: SY='Y';  M= -47, -60, -45, -41,  -9, -55, -19, -42, -22, -37, -31, -43, -57, -29,  18, -41, -43, -44, -16,  48; D=-28;
/I:         I=-28; DM=-71;
/M: SY='H';  M= -22, -33,  -6,  -6, -20, -23, 109, -39, -10, -21,  -6,   5, -22,   0,  -4, -11, -20, -38, -56,  11;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='G';  M= -11, -29, -23, -30,  38,  54, -13, -22, -23, -16, -15, -12, -27, -23, -26, -10, -20, -23,  -4,  38;
/M: SY='H';  M= -22, -33,  -6,  -6, -20, -23, 109, -39, -10, -21,  -6,   5, -22,   0,  -4, -11, -20, -38, -56,  11;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='P';  M= -29, -56, -33, -22, -58,  17, -32, -51, -26, -51, -38, -27,  35,  28, -30, -24, -35, -52, -46, -44; D=-28;
/I:         I=-28; DM=-71;
/M: SY='C';  M= -17, 105, -19, -19, -22, -27,  75, -34, -20, -21, -14,  -7, -33, -17, -19, -14, -16, -26, -55,  -9;
/M: SY='C';  M= -18,  94, -16, -16, -22, -26,  86, -35, -18, -21, -12,  -4, -31, -12, -15, -13, -17, -28, -55,  -3;
/M: SY='P';  M= -10, -26, -18, -13, -23, -23, -24,  -4, -15, -16, -12, -15,  68, -19, -24,  -4,  35,  14, -37, -24;
/M: SY='V';  M=  -7, -17, -25, -23,  -7, -30, -27,  15, -21,  19,   4, -17, -24, -22, -24,  -6,  35,  37, -37, -14;
/M: SY='S';  M=   2, -16, -13, -13, -20, -11, -17,  -6, -12, -16, -14,  -2, -17,  -8, -17,  44,  32,  14, -37, -18;
/M: SY='L';  M= -13, -20, -29, -24,   2, -28, -19,  10, -25,  49,  13, -25, -32, -17, -24,  10,  -8,   4, -26,  -8;
/I:         I=-26; MD=-65;
/M: SY='F';  M= -38, -40, -46, -39,  63, -43, -33, -18, -39, -12, -19, -40,  34, -47, -40, -36, -30, -24, -12,   7; D=-26;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='N';  M= -27, -40, -17, -31, -50, -24, -23, -50, -26, -56, -45,  41, -44, -24, -33,  14, -16, -48, -65, -44; D=-26;
/I:         I=-26; DM=-65;
/M: SY='C';  M= -14, 128, -33, -34, -24, -29, -33, -31, -29, -21, -22, -20, -44, -37, -36, -16, -14, -18, -54, -35;
/M: SY='G';  M=  -4, -29, -15, -19, -34,  68, -20, -41,  16, -37, -26,  -2, -19, -12, -12,  -3, -18, -34, -26, -27;
/M: SY='H';  M= -22, -33,  -6,  -6, -20, -23, 109, -39, -10, -21,  -6,   5, -22,   0,  -4, -11, -20, -38, -56,  11;
/M: SY='H';  M=  12, -26,  46,   0, -24, -18,  55, -11, -13, -17, -13,   0, -22,  -9, -16,  -7,  -9,  10, -46, -11;
/M: SY='I';  M=  18, -23, -33, -28,  -7, -28, -34,  49, -26,   8,   6, -25, -25, -24, -30, -14,  -8,  32, -29, -13;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='G';  M=  -7, -31, -16, -18, -33,  60, -16, -40,   0, -34, -23,  -5, -23,  -8,  40,  -6, -20, -34, -27, -24;
/M: SY='S';  M=   7, -16,  -8,  -9, -27,  -2, -11, -26,  -9, -30, -23,   3, -16,  -1, -14,  61,  12, -19, -35, -19;
/M: SY='T';  M=  -8, -21,  -5,  -9, -27,  23, -12, -24,  24, -27, -18,  32, -17,  -6,  -3,   3,  35, -19, -35, -21;
/M: SY='Y';  M= -12, -26,  -9,  23,   4, -29,  -5,  -3, -10,  -9,  -7, -15, -21,  -7, -15,  -8,  20,  13,  -7,  52;
/M: SY='C';  M= -14, 128, -33, -34, -24, -29, -33, -31, -29, -21, -22, -20, -44, -37, -36, -16, -14, -18, -54, -35;
/M: SY='T';  M=  -6, -21,  30,  -1, -27, -15, -13, -23,  20, -25, -20,   4, -15,  -4,  -4,  26,  37, -16, -38, -19;
/M: SY='M';  M= -10, -26, -23, -13, -15,  20,  -7,  -2, -11,   4,  67, -12, -21,  34, -11, -12, -14,  -7, -26,  -9;
/M: SY='C';  M= -14, 128, -33, -34, -24, -29, -33, -31, -29, -21, -22, -20, -44, -37, -36, -16, -14, -18, -54, -35;
/M: SY='E';  M=  -4, -27,   3,  40, -33, -14,  -6, -30,   1, -28, -20,  -2, -13,  40,  -4,  34,  -1, -25, -31, -20;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='S';  M=   3, -19, -13, -14, -20,  -8, -16,  13, -13, -16, -13,  -1, -18,  -5, -17,  53,   8,  -4, -33, -16;
/M: SY='P';  M= -19, -44, -19,  -8, -38, -21, -22, -26, -15, -37, -23, -26, 101, -19, -28, -16, -11, -31, -32, -36;
/M: SY='V';  M= -10, -24, -24, -14, -12, -32, -26,  29,  30,   0,   0, -17, -24, -12,  -3, -16,  -7,  37, -31, -14;
/M: SY='Q';  M= -11, -28, -19,  -8, -18,  27, -10,  -8,  -9,  14,  35, -11, -23,  45, -10, -10, -16, -12, -25, -12;
/M: SY='M';  M=  20, -20, -19, -11, -18, -13, -11,  -7,  18,  -4,  50, -10, -19,  -4,  -5,  16,  -4,  -7, -28, -13;
/M: SY='V';  M=  -9, -24,  26, -15, -14,  26, -23,   6, -22,  13,  -3, -12, -27, -20, -26, -13, -10,  27, -35, -17;
/M: SY='P';  M= -18, -35, -10,  -6, -32, -20,  -8, -31,   9, -32, -20,  25,  60,  -2,  49, -11, -11, -30, -33, -23;
/M: SY='T';  M=  -5, -19,  -8,  -4, -25, -16, -14, -21,  34, -24, -17,   1, -14,  -2,   3,  26,  40, -14, -33, -18;
/M: SY='P';  M= -11, -29, -11,  21, -23, -28, -20,   1,  19, -13, -10, -17,  47,  -7,  -7, -14,  -8,  25, -33, -22;
/M: SY='P';  M= -21, -29, -30, -21,  34, -31, -21,   1, -25,  31,   4, -31,  60, -25, -28, -24, -15,  -6, -17,  -3;
/I:         E1=0; IE=-255; DE=-255;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 9 in 9 different sequences
Number of true positive hits 9 in 9 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] AV ZBD
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
9 sequences

RPOA_EAVBU  (P19811), RPOA_LDVC   (Q06502), RPOA_LDVP   (Q83017), 
RPOA_PRRS1  (Q9YN02), RPOA_PRRSB  (Q8B912), RPOA_PRRSL  (Q04561), 
RPOA_PRRSR  (Q9WJB2), RPOA_PRRSS  (A0MD28), RPOA_SHFV   (Q68772)
» more

PDB
[Detailed view]
2 PDB

4N0N; 4N0O