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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00985


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00985
General rule information [?]

Accession PRU00985
Dates 18-APR-2016 (Created)
19-NOV-2022 (Last updated, Version 8)
Data class Domain;
Predictors PROSITE; PS51652; AV_ZBD
Name Arteriviridae zinc-binding (AV ZBD) domain
Function The ZBD is comprised of about 80 to 100 residues, including 12 to 13 conserved Cys/His residues. It consists of a RING-like module and treble- cleft zinc finger, together coordinating three Zn atoms.
Scope(s) Viruses
Arteriviridae
Example(s) Q9YN02;

Propagated annotation [?]

Keywords [?]

Metal-binding
Zinc
end case
Zinc-finger

Gene Ontology [?]

case <FTGroup:1> or <FTGroup:2> or <FTGroup:3>
GO:0046872; Molecular function:metal ion binding
GO:0008270; Molecular function:zinc ion binding

Features [?]

From: PS51652
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="AV ZBD #"
BINDING 7 7 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 C 1
BINDING 10 10 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 C 1
BINDING 20 20 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 C 2
BINDING 25 25 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 C 1
BINDING 28 28 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#1"		 [CH] 1
BINDING 32 32 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2
BINDING 34 34 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2
BINDING 36 36 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#2"		 [CH] 2
BINDING 44 44 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#3"		 C 3
BINDING 46 46 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#3"		 [CH] 3
BINDING 53 53 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#3"		 C 3
BINDING 56 56 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_label="#3"		 [CH] 3

Additional information [?]

Size range 54-78 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]