PROSITE entry PS51665
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS51665 |
| Entry name [info] | ENKURIN |
| Accession [info] | PS51665 |
| Entry type [info] | MATRIX |
| Date [info] |
01-FEB-2013 CREATED;
10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51665 |
| Associated ProRule [info] | PRU01000 |
Name and characterization of the entry
| Description [info] | Enkurin domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=93; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=88; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.8593566; R2=0.0047969; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=15482.0000000; R2=0.0000000; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=1489; H_SCORE=15482; N_SCORE=10.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=759; H_SCORE=15482; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-36; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='K'; M= -36, -60, -51, 38,-105, -53, -15, -12, 58, -24, -58, -3, -8, 58, 19, -11, -48, -33,-108, -96; /M: SY='R'; M= -55, -63, -16, 28, -53, -88, 1, -46, -7, -40, -9, -40, -42, -31, 79, -5, -24, -5, -60, 41; /M: SY='K'; M= 2, -61, -64, -3,-102, -98, -15, -28, 58, -11, -46, 40, -26, 32, 36, -13, -27, -38,-108, -42; /M: SY='E'; M= 12,-105, 14, 58, -69, -49, -7, 4, 26, -15, -8, -19, -65, 11, -19, -13, 13, -75,-110, -68; /M: SY='E'; M= -3,-108, -7, 72, -62, -77, 2, -38, 22, -22, -28, -2, -95, 54, -1, -19, -89, -46,-109, -71; /M: SY='W'; M= -8,-107, -94, 28, -93,-103, -42, 8, 17, -9, 5, -26, -61, 30, 16, -4, -27, 25, 87, -61; /M: SY='K'; M= 8, -27, -16, 40,-105, -75, -59, -26, 48, -40, -17, -47, -30, 15, 46, 5, -24, -22, -54, -97; /M: SY='R'; M= 14,-107, -22, 47, -43, -71, -87, -63, 44, -54, -36, -25, -48, 25, 55, -20, -50, -54,-104, 6; /M: SY='E'; M= 45,-104, 11, 58,-101, -51, -56, -16, 7, -33, -50, -12, -51, -5, -1, -26, -16, -36,-107, 1; /M: SY='Q'; M= 8,-107, -47, 46, -20, -75, -42, 17, -14, -4, -1, 14, -40, 69, -2, -59, -24, -65, -21, -20; /M: SY='E'; M= 10,-107, -23, 77, -56, -71, -22, 1, 19, -26, -53, -29, -63, 15, -8, -58, -15, -28,-107, -20; /M: SY='E'; M= 17,-106, -9, 64, -36, -73, -1, -59, 17, -41, 26, -23, -96, 33, 14, -1, -43, -26, -51, -49; /M: SY='R'; M= -4,-108, -18, 22, -20, -60, -61, -25, 3, -33, -21, 2, -12, 28, 56, -27, -35, -22, -97, 54; /M: SY='E'; M= -6, -20, 32, 38, -32, -75, 6, 0, 16, -5, -18, -12, -46, 35, 28, -34, -16, -44,-109, -46; /M: SY='Q'; M= 17,-106, -29, 44, -59, -98, 19, -20, 0, -28, 0, 17, -98, 47, 47, -8, -47, -49, -50, -66; /M: SY='Q'; M= 7,-105, 3, 17, 7, -71, -72, -61, -1, -22, -2, 42,-101, 51, -12, 12, -28, -49, -43, 47; /M: SY='Q'; M= -7,-103, -25, 22, -59, -34, -27, 8, 3, 9, 6, -25, -41, 30, 8, 11, 0, 24,-109, -93; /M: SY='Q'; M= -11,-110, -8, 44, -62, -61, -56, -21, 31, -24, -8, -60, 48, 55, 32, -59, -65, -46,-107, -69; /M: SY='E'; M= 0,-108, 60, 61, -77, -45, -10, -34, -1, -39, -65, -31, -1, 27, -6, -25, -26, -49,-113, -58; /M: SY='P'; M= 5,-108, -7, 30, -82, -85, 10, -20, 6, -11, -41, -4, 67, 39, -7, 1, -44, -40,-110, -76; /M: SY='M'; M= -7, -32, 26, 34, -66, -74, -25, -46, 34, -4, 45, 7, 14, -24, 10, -2, -10, -43,-110, -72; /M: SY='C'; M= 11, 56, -62, 31, -99, -1, -31, 5, 6, -51, 38, -65, -17, 44, 2, -14, -28, -22,-107, -6; /M: SY='P'; M= -24,-112, -17, -2,-106, -83, -7, -1, 28, -38, 4, -7, 86, 41, -4, -43, -44, -42,-109,-100; /M: SY='P'; M= -2, -45, 12, 7, -44, 8, -21, -47, -7, -85, -98, 2, 75, 31, 1, 18, -37, -70,-110,-101; /M: SY='G'; M= 25,-105, -93, -35,-108, 66, 3, -55, 17, -50, -67, -53, -29, 31, 12, -16, -32, -34,-107,-100; /M: SY='H'; M= -36, 20, -56, -14, -12, -61, 87, -21, -25, 5, 74, -44, -32, 18, -20, -64, 13, -13,-108, 1; /M: SY='R'; M= 12, -60, -70, -9, -77, -69, -49, -21, 31, -48, -43, -89, -21, 16, 65, -63, 31, 12,-104, 14; /M: SY='L'; M= -47, -21, -44, 13, -30, -57, 4, -46, 15, 38, 33, -22, 11, 23, 36, -37, -68, -15,-102, 9; /I: I=-8; MD=-21; /M: SY='M'; M= -63,-104, -23, 4, -83, -84, -4, 11,-100, 53, 96,-103,-107, -19,-101, -61, -66, -1,-107, -41; D=-8; /I: I=-8; MD=-21; /M: SY='P'; M= -19, -98, 30, -10,-110, -36, -55, -44, -46, -43,-101, -79, 62, -46, -1, 61, 5,-101,-116, -64; D=-8; /I: I=-8; MI=0; MD=-21; IM=0; DM=-21; /M: SY='E'; M= -36,-113, 53, 81, -87, -45, -63, -72, -29, -64,-103, -62, 11, 26, -18, -19, -75, -78,-116, -85; D=-8; /I: I=-8; DM=-21; /M: SY='E'; M= 15, -41, 35, 74, -74, -36, -15, -81, -11, -81, -98, 5, -35, 39, -49, 17, -45, -70,-111, -61; /M: SY='E'; M= -72,-111, 19, 105, -86, -79, -84,-112, -20, -86, -53, -84, -60, 41, -55, -68, -71,-107,-111,-101; /M: SY='R'; M= -95,-111, -93, -48,-102,-106, -16, -46, 21, -10, -89, -87,-104, 27, 104, -55, -46, -36,-106, -92; /M: SY='Q'; M= 0, -50, -8, 21, -56, -70, -34, -10, 19, 25, 13, -1,-100, 69, 2, -63, -37, -4,-106, -67; /M: SY='E'; M= 27, -71, -5, 66,-107, -14, -47, -46, 11, -39, -39, -20, -94, 47, 9, -5, -24, -76, -31, -67; /M: SY='L'; M= -2, -98,-104, -72, -81,-107, -2, 31,-100, 58, 17, -75,-104, -64,-102, -69, 57, 5,-106, -23; /M: SY='L'; M= -95, -52,-111, -57, -76,-115, -99, 25, -40, 79, 14,-108,-111, -70, 8, -76, -92, 9,-104, -86; /M: SY='Q'; M= -15, -53, 42, 44,-107, -61, -3, -26, 9, -54, -95, 37, -65, 50, 19, 8, -10, -51,-112, -63; /M: SY='G'; M= 6, -57, -4, -3,-106, 61, -5, -52, 21, -40, 2, 28, -64, 10, -24, -2, -40, -36,-109, -99; /M: SY='L'; M= 14, -99, -75,-104, -76,-109, -99, -30,-105, 85, 35,-109, -71, -99,-104, -76, -60, -44,-103, -86; /M: SY='K'; M= -41,-109, -40, -16, -62,-101, 9, -79, 85, -31, -92, -25, -65, 49, 52, -87, -65,-103,-104, -50; /M: SY='Q'; M= 29,-104, -58, 20, -48, -89, -41, -21, 55, -39, -47, 12, -66, 59, 10, -25, -8, -35,-106, -49; /M: SY='N'; M= -34,-104, -41, -21,-106, -55, 9, -66, 58, -76, -51, 65, -99, -34, 61, 22, -22,-103,-111, -96; /M: SY='W'; M=-100,-117,-105, -26, -21,-105, 28, -51, 4, -3, -52, -38,-106, 46, 0, -99,-102,-102, 143, 53; /M: SY='D'; M= -5, -55, 60, 43, -68, -22, -85,-107, -1, -84, -53, 36, -96, 35, 2, 19, -3, -67,-113, -46; /M: SY='E'; M= -26,-108, 28, 73, -80, -69, -29, -68, 22, -22, -53, -47, -94, 56, -16, -5, -25, -33,-109, -57; /M: SY='L'; M= -30, -6,-109, -46, -77, -77, -99, 18, -32, 70, 18, -51,-110, -98, -56, -81, -37, 31,-103, -1; /M: SY='N'; M= -50,-103, -73, 5, -59, -73, 55, 29, -61, -5, 13, 73,-102, 19, -44, -16, -10, 8,-110, 1; /M: SY='K'; M= 20, 6, -11, 13, -67, -52, 32,-102, 53, -56, -36, 24, -98, -21, 27, 14, -18, -48, 2, -5; /M: SY='E'; M= -24,-110, 10, 88,-112,-102, -84, -78, 3, -73, -61, -49, -92, 64, 17, -29, -54, -81,-110, -99; /M: SY='Y'; M=-102,-108,-109,-107, 36,-113, -25, -30,-102, 49, -18,-107,-115, -98, -59,-102, -58, -83, -1, 107; /M: SY='Q'; M= -29, -35, -39, -44, -49, -41, -14, -58, -79, -8, -43, 65,-102, 97, 1, -36, -28, -15,-110, -94; /M: SY='K'; M= -45, -1, -80, -75,-103, 9, 45,-102, 51, -11, 16, -50,-100, 12, 42, 38, -9, -94,-110, -93; /M: SY='M'; M= -75,-103,-114,-106, -11, -73, -97, 23, -56, 69, 82,-108,-110, -38, -39,-104, -39, -51,-101, -4; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='P'; M= -62,-112, -95, -88,-113, -32, -99,-105, -42,-113,-102, -44, 111, -93,-102, 45, 14,-105,-113,-109; /I: I=-33; MI=0; MD=-84; IM=0; DM=-84; /M: SY='F'; M= -27, -35,-112,-107, 51,-112, 49, 26,-105, 33, 45,-104,-110,-103,-104, -64, -56, 49,-102, -78; /M: SY='S'; M= -25, -94, -99, -69, -34, -5, -48, 25, -1, 1, -18, -58,-102, -90, 29, 41, 27, 25,-110, -93; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='M'; M= 12, -6, -54, -36, -10, -93, -45, 43, -15, 4, 43, -10, -83, -30, -54, -5, 32, 11,-107, -14; /M: SY='D'; M= -76,-112, 102, 26, -65, -7, -87,-114, -38,-113, -52, 0, -17, 23, -92, -87, -71, -78,-124,-102; /M: SY='T'; M= -67, -95, -89, -93,-100, -97, -62, -72, -90, -58, -93, -2, -94, -92, -66, 37, 106, -59, -14, -97; /M: SY='L'; M= -12, -67, -76, -28, -15,-110, -49, 15, -98, 50, 33,-105, 46, 5, -16, -98, -36, 8,-104, -13; /M: SY='R'; M= -7,-108, -94, -89, -78, 21, -30, -74, -21, -54, -63, -10, 46, -5, 62, 44, -35, -44,-109, -46; /M: SY='K'; M= -2,-105, -98, -55, -46, -60, -28, 6, 64, 5, -4, -92,-102, 46, -35, -44, -31, 28,-107, -49; /M: SY='R'; M= -26, -77, -96, -83,-102,-106, -57, 9, 59, -22, 18, -70,-103, 49, 71, -91, -69, -30,-107, -94; /M: SY='N'; M= 4,-106, -58, -24, -88, -56, -29, -28, 34, -34, -32, 57,-102, 34, 51, 16, -39, -52,-111, -59; /M: SY='R'; M= -59, -82, -94, -85, -81,-107, 63,-105, 34, -19, -91, -44,-105, -23, 94, -69, -47, -43,-109, -20; /M: SY='K'; M= -49,-111, -89, -59,-111,-103, -11,-111, 100,-109, -97, -82, -98, -10, 52, -90, -91, -85,-106, -97; /M: SY='E'; M= 35,-105, -31, 67,-106, -47, -31, -9, -16, -57, 21, -14, -96, 5, 9, -3, -8, -54, -14, -99; /M: SY='E'; M= 8, -15, 9, 60, -82, -54, -9, -84, 19, -57, -21, 2, -51, 49, 17, -33, -27,-103, 23, -30; /M: SY='L'; M= -98, 26,-115,-109, -14,-116, -34, 43,-108, 67, 49,-110,-113, -48,-106, -75, -94, -21,-100, 20; /M: SY='E'; M= -92,-113, 24, 108,-116, -31, -87,-117, -76,-110,-106, -63, -89, -69, -86, -58, -59,-110,-114,-106; /M: SY='K'; M= -2, -7, -35, 8, -79, -62, 2,-107, 63, -58, -96, -2, -99, 47, 47, -5, -15, -72,-110, -97; /M: SY='Q'; M= -67, -36, -4, 70,-114, -58, -86, -81, 34,-107, -99, -44, -95, 74, 30, -38, -24,-107,-109, -56; /M: SY='L'; M= -72, -34,-115, -78, -76,-116,-100, 17,-108, 82, 58, -60,-113,-101,-106, -55, -94, -41,-105, -87; /M: SY='K'; M= 25,-104, 41, -21, -65, -48, -92, -30, 41, -62, -60, 26, -52, 7, 7, -1, 5, -5,-113, -51; /M: SY='Q'; M= -13,-112, -8, 56, -62, -62, -37, -20, -25, -60, -93, -20, -98, 95, -19, -50, -61, -30, 14, -96; /M: SY='I'; M= -96,-104,-116,-111, -79,-119,-108, 64, -79, 60, -36, -56,-112,-106,-109,-105, -52, 39,-107, -31; /M: SY='E'; M= -95,-114, 54, 103,-117,-106, -87, -84, -59,-111,-108, -47, -91, -35, -87, -61, -93,-110,-117,-106; /M: SY='K'; M= -12,-110, 3, 47, -21, -76, -2, -79, 56, -85, -98, 1, -52, 24, 17, -10, -57, -53,-105, 15; /M: SY='D'; M= 52,-105, 90, -13,-112, -27, -92,-109, -90, -88,-105, -18,-100, -88, -68, -9, -34, -81,-120, -32; /M: SY='I'; M= -98,-110,-115, -49, -83,-121, -38, 98, -55, 10, 31,-108,-108, -34, -48,-106, -93, -38,-107, -89; /M: SY='K'; M= 11, -39, -21, 28,-108, -32, -22,-105, 54, -26, -96, 18,-100, 26, 27, 2, -38, -57, -44, -67; /M: SY='K'; M= -67,-106,-102, -55, -68,-111, -41, 41, 52, 18, 43, -38,-104, -29, -10, -95, 16, 17,-107, -22; /M: SY='F'; M= -73,-105,-117,-112, 79,-117,-101, 25, -79, 55, -22,-111,-116,-109,-108, -76, -58, -20, -89, 18; /M: SY='S'; M= -71,-106, 13, 66,-113, -56, -25,-112, -24,-111,-104, 21, -95, 10, -88, 72, -41,-106,-117,-102; /M: SY='R'; M= -42,-111, -91, -60,-109, -40, -49,-109, 67, -39, -96, 3,-102, 28, 72, -17, -8,-105,-110, -98; /M: SY='P'; M= -2, -36, 6, -46, -17, -29, 60,-107, -1, -67, -98, 12, 66, 16, 3, -3, -6,-106,-112, -21; /M: SY='K'; M= -24,-111, -26, -49, -67, -30, 42, -46, 65, -75, -78, 10, 37, 3, 6, -49, 0, -45,-108, 9; /M: SY='V'; M= -67, -38, -37, -47, -31,-114, 3, 26, -82, -29, -4, -38, -47, -50, -65, -56, -12, 78,-110, 22; /M: SY='F'; M= -90,-110, -27, -74, 72,-117, -14, 44, -65, 8, -41, -73,-115, -50, -78, -69, -97, -12, -86, 68; /M: SY='Y'; M= -96,-108,-114, -75, -1,-118, -20, 40, -65, -18, 2,-110,-114,-105, -79, -60, -93, 64, -12, 72; /M: SY='K'; M= -28,-109, 4, -18, -35, -91, -70, 17, 42, -40, -19, -26, -9, -14, -11, -19, -38, 33,-106, 32; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 7 in 7 different sequences |
| Number of true positive hits | 7 in 7 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | enkurin |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
7 sequences
ENKD1_BOVIN (Q3T078), ENKD1_HUMAN (Q9H0I2), ENKD1_MOUSE (Q7TSV9), ENKUR_BOVIN (E1B836), ENKUR_HUMAN (Q8TC29), ENKUR_MOUSE (Q6SP97), ENKUR_PIG (A0A4X1TZW7)» more
|
| PDB [Detailed view] |
10 PDB
7RRO; 7UNG; 8I7O; 8I7R; 8IYJ; 8J07; 8OTZ; 8TO0; 9CPB; 9CPC |