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| Entry: PS51669 |
General information about the entry
| Entry name [info] | 4FE4S_MOW_BIS_MGD |
| Accession [info] | PS51669 |
| Entry type [info] | MATRIX |
| Date [info] |
01-MAR-2013 CREATED;
26-FEB-2020 DATA UPDATE; 12-AUG-2020 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00392 |
| Associated ProRule [info] | PRU01004 |
Name and characterization of the entry
| Description [info] | Prokaryotic molybdopterin oxidoreductases 4Fe-4S domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=57; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=52; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1464889; R2=0.0093127; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=8416.6923828; R2=1.6901028; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=790; H_SCORE=9752; N_SCORE=9.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=468; H_SCORE=9208; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-28; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='M'; M= -5, -71, 38, 14, -19, -25, -60, 5, -62, 35, 73, 0, -70, -7, -66, -21, 4, -50, -77, -59; /M: SY='K'; M= -22, -74, -57, -6, -71, -18, -59, -24, 71, -71, -63, -51, -7, 9, 26, 9, 39, -65, -73, 6; /M: SY='V'; M= -60, -73, -60, 29, -3, -74, -65, 36, 29, -25, -52, 19, -69, -9, -58, -19, 16, 37, 35, 9; /M: SY='T'; M= -1, -67, -14, -66, -2, 8, 6, 9, -65, -54, -54, -57, -69, -66, -70, -15, 68, 46, -76, 13; /M: SY='P'; M= -63, -80, 19, 6, -74, -71, 11, -66, 50, -70, 3, -17, 58, 16, 35, -59, -21, 5, 41, -64; /M: SY='S'; M= 3, -64, -58, -60, -71, 3, -62, -66, -58, -68, 24, -10, -63, -55, -64, 76, 68, -59, -83, -66; /M: SY='I'; M= 22, -69, -71, -66, -59, -72, -73, 57, -66, -6, -46, -64, -8, 26, -70, -23, 48, 35, -79, -62; /M: SY='C'; M= -63, 140, 37, -66, -73, -74, 65, -80, -70, -71, -68, -57, -84, -72, -74, -62, -61, -70,-102, -71; /M: SY='P'; M= -4, 41, -62, 21, -17, -17, -67, 5, -59, -30, -60, -61, 67, 6, -16, 15, 23, -3, -79, -67; /M: SY='Y'; M= -65, -74, -72, -72, 47, -7, 57, -8, -68, 10, 63, 5, -78, -64, -67, -66, -62, 7, -55, 74; /I: I=-45; MI=0; MD=-115; IM=0; DM=-115; /M: SY='C'; M= -62, 147, 36, -70, -73, -75, -76, -79, -73, -71, -71, -61, -87, -79, -80, -63, -61, -68,-102, -80; /M: SY='W'; M= 10, 23, -64, -66, -70, 47, -69, -66, -64, -27, -64, -6, 26, -62, -70, 36, 40, -11, 59, -66; /M: SY='V'; M= -10, -68, 12, -66, -10, 17, -71, -39, -67, -9, 24, -60, -72, -66, -71, 22, 22, 64, -81, -61; /M: SY='G'; M= -52, -75, -61, -62, -76, 77, -62, -77, -56, -11, -65, 2, -69, 44, 25, 23, -60, -75, -75, -70; /M: SY='C'; M= -59, 147, -77, -77, -71, -74, -78, -76, -74, -69, -68, -63, -86, -79, -80, 0, 12, -65, -99, -79; /M: SY='G'; M= 18, -73, -60, -60, -80, 63, -65, -78, 12, -79, -69, 3, 47, -1, -62, 31, -7, -72, -77, -73; /M: SY='W'; M= -65, -75, -86, -80, 33, -85, -78, 71, -76, 34, 26, -78, -77, -74, -77, -73, -16, 14, 79, -47; /M: SY='N'; M= -61, -74, 18, 10, -69, -34, -55, -6, -5, 10, -57, 50, -70, 30, 49, 4, 14, -62, -81, -64; /M: SY='V'; M= 35, -68, -78, -73, -51, -74, -71, 43, -71, 10, 35, -72, -75, -69, -73, -61, -14, 57, -72, 28; /M: SY='H'; M= -60, -76, 37, -55, 5, 14, 55, -60, -56, -64, -59, -5, -72, 39, 10, -4, -16, 23, 38, 44; /M: SY='V'; M= -2, -67, -64, 15, -63, -73, 7, -38, -11, -52, -52, -62, -69, -61, -19, -5, 49, 73, -85, -63; /M: SY='K'; M= -28, -76, 24, -5, -76, -68, -57, -69, 78, -40, -63, 10, -66, 31, 30, -17, -56, -4, -78, -65; /I: I=-29; MI=0; MD=-75; IM=0; DM=-75; /M: SY='D'; M= -24, -75, 65, -50, -73, 40, -57, -71, 1, -73, 8, 40, -12, -2, -15, -9, -20, -15, -80, 7; /M: SY='G'; M= -11, -75, -4, -18, -80, 82, 5, -84, -57, -81, -71, 31, -68, -58, 22, -49, -3, -78, -78, -72; /M: SY='K'; M= -32, -78, -7, 49, -72, -31, 11, 27, 59, -65, -60, -55, -65, -45, 45, -25, -59, -22, -77, -64; /M: SY='I'; M= -9, -73, -25, -70, -7, -22, -77, 65, -9, -15, -45, -69, 7, -10, -71, -63, -13, 54, -77, -59; /M: SY='M'; M= -59, -69, -73, -19, 29, -77, 9, 26, -9, 8, 75, -66, -72, -64, -66, -12, 27, 42, -74, -51; /M: SY='R'; M= -27, -79, -64, -56, 17, -36, 3, -32, 33, -68, -61, -14, -74, -47, 86, -23, -63, -69, 47, 35; /M: SY='I'; M= -21, 12, -69, 30, -56, -82, -76, 75, -66, -24, -44, -70, -71, -64, -18, -64, -2, 47, -79, -61; /M: SY='E'; M= 0, -76, -11, 62, -69, -72, -1, -64, -45, 20, -56, -58, -66, 41, 46, -17, -5, -30, -78, -64; /M: SY='G'; M= 13, -77, -62, -60, -80, 63, -65, -12, -60, -75, -66, 2, 59, 49, -67, -13, -10, -69, -76, -73; /M: SY='D'; M= -5, -77, 71, -46, -76, -12, -54, -10, -46, -28, -65, 50, -71, 29, 54, -54, -58, -69, -85, -67; /M: SY='P'; M= -19, -78, -56, 22, -68, -66, -60, 23, -25, -68, -62, 48, 76, 2, -14, -5, -4, -61, 37, 7; /M: SY='D'; M= -62, -77, 57, 22, -71, -21, 55, -73, 36, -73, -66, 34, -67, 20, -19, -16, -9, -20, -79, 21; /M: SY='H'; M= 8, -78, 48, -52, -62, -20, 102, -76, -14, -71, -62, 29, 21, -53, -58, -55, -60, -75, -75, 52; /M: SY='P'; M= -18, -82, -62, 9, -81, 10, -67, -71, -11, -78, -68, -64, 103, -59, 11, -57, 12, -26, -79, -76; /I: I=-13; MD=-33; /M: SY='V'; M= 5, -71, -70, -14, -60, -73, -69, 26, -64, 5, -49, -66, -73, 45, -67, 23, -1, 51, -77, 0; D=-13; /I: I=-13; MI=0; MD=-33; IM=0; DM=-33; /M: SY='N'; M= -3, -68, -46, -58, -65, -57, 18, -68, -51, -70, 24, 98, -71, -1, -6, -13, 31, -68, -79, 29; /M: SY='E'; M= -18, -78, -46, 67, -19, 14, 21, -79, -44, -74, -66, 29, -65, 55, 32, -15, -60, -75, -75, -11; /M: SY='G'; M= -55, -78, -57, 46, -72, 68, -65, 5, -61, -71, -66, -57, 45, -58, -69, -20, -15, -21, -73, 6; /M: SY='W'; M= -32, -77, -67, -60, -2, -70, 0, -69, 18, -32, 8, 0, -71, -53, 65, 0, 33, -68, 112, -49; /M: SY='I'; M= -5, -72, -76, -76, -52, 22, -74, 62, -73, 47, -40, -11, -75, -70, -76, -64, -12, 8, -75, -60; /M: SY='C'; M= -59, 147, -77, -77, -71, -74, -78, -76, -74, -69, -68, -63, -86, -79, -80, 0, 12, -65, -99, -79; /M: SY='D'; M= 36, -73, 62, -51, -70, -26, -63, 10, -61, -7, -57, 1, 18, 34, -66, -55, -56, 22, -83, -67; /M: SY='K'; M= -20, -77, -59, -46, -75, -71, -57, -76, 90, -28, -63, -52, -67, -41, 66, -58, -59, -72, -73, -64; /M: SY='G'; M= -49, -74, -66, -75, -77, 95, -72, -71, -69, -76, -69, -52, -69, -68, -76, -50, 5, 15, -76, -75; /M: SY='R'; M= 47, -74, -62, 1, -68, 1, -56, -72, -8, -68, 22, -18, -70, -48, 78, -53, -60, -65, -70, 25; /M: SY='F'; M= -28, -70, -13, -67, 79, -31, -61, -10, -64, -53, 7, 27, -74, -65, -24, 39, 6, -9, -59, 23; /M: SY='H'; M= -13, -1, -70, -71, 0, 52, 58, -53, -68, 22, 42, -60, -73, -64, -70, -11, -21, 10, -72, 15; /M: SY='W'; M= -63, 29, -72, -22, 19, -31, 48, -17, -64, -1, 9, -66, -10, -62, -11, 10, -8, -6, 101, 54; /M: SY='D'; M= -61, -78, 65, 55, -78, -67, 12, -79, -13, -76, -70, 3, -64, 37, 12, 12, 11, -75, 46, -64; /M: SY='W'; M= -60, -75, -69, -65, 46, -6, 25, -20, -20, -14, -57, -60, -74, 4, 15, 43, -18, -62, 78, 57; /M: SY='M'; M= 23, -68, -74, -70, -51, -70, -66, 37, -69, 28, 54, -67, -73, -64, -70, 28, -14, 26, -70, 28; /M: SY='Y'; M= -33, -77, 16, 3, -49, -29, 26, -68, 27, -22, -59, 54, -72, -1, 9, -57, -59, -69, -57, 84; /M: SY='Q'; M= -56, -74, 50, -6, -74, -23, -56, 4, -14, -36, -63, 37, -68, 53, 8, 47, -51, -16, -83, -66; /M: SY='P'; M= -19, -81, -2, 37, -79, -68, -60, 3, 0, -72, -64, 0, 81, 36, 9, -6, -10, -66, -79, -71; /M: SY='D'; M= -61, -78, 67, 37, -75, -29, -53, -77, -6, -39, -68, -11, -66, 42, 43, 7, -5, -74, -80, -1; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 238 in 238 different sequences |
| Number of true positive hits | 238 in 238 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 1 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 99.58 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Archaea, Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 1 |
| Feature key [info] | DOMAIN |
| Feature description [info] | 4Fe-4S Mo/W bis-MGD-type |
| Version [info] | 6 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
238 sequences
CLRA_IDEDE (P60068 ), DADHH_EGGLE (C8WLC6 ), DADH_EGGLN (A0A369NIV7), DDHA_RHOSU (Q8GPG4 ), DMSA_ECOLI (P18775 ), DMSA_HAEIN (P45004 ), DMSA_HALSA (Q9HR74 ), FDHA_DESGI (Q934F5 ), FDHA_METFO (P06131 ), FDHA_METJA (P61159 ), FDHF_ECOLI (P07658 ), FDHL_BACSU (Q795Y4 ), FDHL_STAA3 (Q2FEI5 ), FDHL_STAA8 (Q2FVV9 ), FDHL_STAAB (Q2YYT1 ), FDHL_STAAC (Q5HDP9 ), FDHL_STAAM (Q931G2 ), FDHL_STAAN (Q99RW4 ), FDHL_STAAR (Q6GEC4 ), FDHL_STAAS (Q6G711 ), FDHL_STAAW (Q7A057 ), FDHL_STAHJ (Q4L8G8 ), FDHL_STAS1 (Q49ZN0 ), FDNGA_DESVH (Q727P3 ), FDNG_ECOLI (P24183 ), FDOG_ECOLI (P32176 ), FDXG_HAEIN (P46448 ), NAPA1_PHOPR (Q6LTV9 ), NAPA2_PHOPR (Q6LQJ3 ), NAPA_ACTP2 (A3N277 ), NAPA_ACTP7 (B3H2D1 ), NAPA_ACTPJ (B0BR28 ), NAPA_ACTSZ (A6VQY7 ), NAPA_AERHH (A0KIM1 ), NAPA_AERS4 (A4SPG7 ), NAPA_AGGAC (Q8VL02 ), NAPA_AGRFC (Q8U7P1 ), NAPA_ALIF1 (Q5E3J6 ), NAPA_ALIFM (B5FGW1 ), NAPA_BORBR (Q7WIQ1 ), NAPA_BORPA (Q7W733 ), NAPA_BORPD (A9I7M5 ), NAPA_BRADU (Q89EN5 ), NAPA_BRASB (A5ED21 ), NAPA_BRASO (A4Z0A1 ), NAPA_CAMC1 (A7ZCK4 ), NAPA_CAMC5 (A7GZP5 ), NAPA_CAMFF (A0RQ36 ), NAPA_CAMHC (A7I3Y7 ), NAPA_CAMJ8 (A8FLJ3 ), NAPA_CAMJE (Q9PPD9 ), NAPA_CAMJJ (A1VZC8 ), NAPA_CAMJR (Q5HV12 ), NAPA_CAMLR (B9KCQ2 ), NAPA_CITK8 (A8AE11 ), NAPA_COLP3 (Q487G4 ), NAPA_CUPNH (P39185 ), NAPA_CUPPJ (Q46RX3 ), NAPA_CUPTR (B3R8B4 ), NAPA_DECAR (Q47A87 ), NAPA_DESDA (P81186 ), NAPA_DINSH (A8LLY9 ), NAPA_ECO24 (A7ZP28 ), NAPA_ECO27 (B7UFL9 ), NAPA_ECO45 (B7MFB8 ), NAPA_ECO55 (B7LAM9 ), NAPA_ECO57 (Q8XE47 ), NAPA_ECO5E (B5YWZ7 ), NAPA_ECO7I (B7NN18 ), NAPA_ECO81 (B7MXN6 ), NAPA_ECO8A (B7M5P6 ), NAPA_ECOBW (C4ZU48 ), NAPA_ECODH (B1X8A2 ), NAPA_ECOHS (A8A268 ), NAPA_ECOK1 (A1AD59 ), NAPA_ECOL5 (Q0TFN6 ), NAPA_ECOL6 (Q8CVW4 ), NAPA_ECOLC (B1IY66 ), NAPA_ECOLI (P33937 ), NAPA_ECOLU (B7N5G7 ), NAPA_ECOSE (B6I1A4 ), NAPA_ECOSM (B1LKV2 ), NAPA_ECOUT (Q1R9L3 ), NAPA_EDWI9 (C5B7B9 ), NAPA_ESCF3 (B7LJU7 ), NAPA_HAEDU (Q7VPJ7 ), NAPA_HAEI8 (Q4QNJ6 ), NAPA_HAEIE (A5UAE1 ), NAPA_HAEPS (B8F7K2 ), NAPA_HAES1 (Q0I5G9 ), NAPA_HAHCH (Q2SGV7 ), NAPA_HELHP (Q7VJT5 ), NAPA_HISS2 (B0URQ3 ), NAPA_LARHH (C1D9G3 ), NAPA_LEPCP (B1Y6A6 ), NAPA_MAGMG (Q93HX3 ), NAPA_MAGSA (Q2W3T1 ), NAPA_MANSM (Q65Q72 ), NAPA_METS4 (B0UCB6 ), NAPA_NAUPA (B9L8L4 ), NAPA_NITSB (A6Q604 ), NAPA_PARPN (Q56350 ), NAPA_PARXL (Q13I15 ), NAPA_PASMU (Q9CKL8 ), NAPA_PECAS (Q6D5Z2 ), NAPA_PECCP (C6DK59 ), NAPA_PSEA7 (A6V924 ), NAPA_PSEA8 (B7UX15 ), NAPA_PSEAB (Q02IZ4 ), NAPA_PSEAE (Q9I4G3 ), NAPA_PSEMY (A4XWM0 ), NAPA_PSEST (Q3HS05 ), NAPA_PSEU5 (A4VJ11 ), NAPA_PSYIN (A1SWQ0 ), NAPA_RALPJ (B2UBL7 ), NAPA_RHIME (Q92Z36 ), NAPA_RHOPB (Q21AR4 ), NAPA_RHOS4 (Q53176 ), NAPA_SACD2 (Q21PN1 ), NAPA_SALA4 (B5EYU5 ), NAPA_SALAR (A9MJZ6 ), NAPA_SALCH (Q57M92 ), NAPA_SALDC (B5FNQ2 ), NAPA_SALEP (B5R233 ), NAPA_SALG2 (B5RC85 ), NAPA_SALHS (B4TAT3 ), NAPA_SALNS (B4SYT3 ), NAPA_SALPA (Q5PI61 ), NAPA_SALPB (A9N5G2 ), NAPA_SALPC (C0Q0P2 ), NAPA_SALPK (B5BDZ4 ), NAPA_SALSV (B4TPE6 ), NAPA_SALTI (Q8Z570 ), NAPA_SALTY (Q8ZNH6 ), NAPA_SERP5 (A8GHJ4 ), NAPA_SHEDO (Q12P44 ), NAPA_SHEHH (B0TSW5 ), NAPA_SHEON (Q8EIJ1 ), NAPA_SHIB3 (B2TV30 ), NAPA_SHIBS (Q31Z29 ), NAPA_SHIDS (Q32I06 ), NAPA_SHIF8 (Q0T2R8 ), NAPA_SHIFL (Q83QV0 ), NAPA_SHISS (Q3Z001 ), NAPA_SYMTH (Q67QZ1 ), NAPA_VIBC3 (A5EZX9 ), NAPA_VIBCB (A7N7J3 ), NAPA_VIBCH (Q9KLR4 ), NAPA_VIBCM (C3LVU3 ), NAPA_VIBPA (Q87GW6 ), NAPA_VIBTL (B7VRL0 ), NAPA_VIBVU (Q8D623 ), NAPA_VIBVY (Q7MD44 ), NAPA_WOLSU (Q7M962 ), NAPA_YERE8 (A1JL26 ), NAPA_YERP3 (A7FG75 ), NAPA_YERPA (Q1C5S8 ), NAPA_YERPB (B2K970 ), NAPA_YERPE (Q8ZCF3 ), NAPA_YERPG (A9QZL3 ), NAPA_YERPN (Q1CK03 ), NAPA_YERPP (A4TMK8 ), NAPA_YERPS (Q668I0 ), NAPA_YERPY (B1JSJ0 ), NARB_SHEFN (O33732 ), NARB_SYNE7 (P39458 ), NARB_SYNY3 (P73448 ), NARG_BACSU (P42175 ), NARG_ECOLI (P09152 ), NARG_HALMT (I3R9M9 ), NARG_MYCTO (P9WJQ2 ), NARG_MYCTU (P9WJQ3 ), NARX_MYCTO (P9WJQ0 ), NARX_MYCTU (P9WJQ1 ), NARZ_ECOLI (P19319 ), NASA_KLEOX (Q06457 ), NASC_BACSU (P42434 ), NDUS1_ACACA (Q37373 ), NDUS1_ARATH (Q9FGI6 ), NDUS1_BOVIN (P15690 ), NDUS1_DICCI (Q2LCP5 ), NDUS1_DICDI (Q34312 ), NDUS1_DROME (Q94511 ), NDUS1_GORGO (Q0MQG1 ), NDUS1_HUMAN (P28331 ), NDUS1_MACFA (Q4R6K9 ), NDUS1_MOUSE (Q91VD9 ), NDUS1_NEUCR (P24918 ), NDUS1_PANTR (Q0MQG2 ), NDUS1_PONAB (P0CB67 ), NDUS1_PONPY (P0CB68 ), NDUS1_RAT (Q66HF1 ), NDUS1_RECAM (O21241 ), NDUS1_SOLTU (Q43644 ), NQO3_PARDE (P29915 ), NQO3_THET8 (Q56223 ), NUOG2_RHIME (P56914 ), NUOG_BLOFL (Q7VRV7 ), NUOG_BUCAI (P57257 ), NUOG_BUCAP (Q8K9Y2 ), NUOG_BUCBP (Q89AU1 ), NUOG_ECO57 (Q8XCX2 ), NUOG_ECOL6 (Q8FFJ9 ), NUOG_ECOLI (P33602 ), NUOG_MYCBO (P59962 ), NUOG_MYCTO (P9WIV8 ), NUOG_MYCTU (P9WIV9 ), NUOG_PSEAE (Q9I0J6 ), NUOG_PSEFL (Q9KGW3 ), NUOG_PSEPK (Q88FH2 ), NUOG_PSESM (Q87ZQ4 ), NUOG_RICBR (Q1RKD2 ), NUOG_RICCN (Q92G92 ), NUOG_RICFE (Q4UK22 ), NUOG_RICPR (Q9ZCF6 ), NUOG_RICTY (Q68VV2 ), NUOG_SALTI (P0A1Y5 ), NUOG_SALTY (P0A1Y4 ), NUOG_SHEON (Q8EI34 ), NUOG_SHIFL (Q7UC56 ), NUOG_STRCO (Q9XAR0 ), NUOG_YERPE (Q8ZDL2 ), PCRA_DECAR (Q47CW6 ), PHSA_SALTY (P37600 ), PSRA_WOLSU (P31075 ), QRCB_DESVH (Q72E84 ), SERA_THASE (Q9S1H0 ), SFRA_GEOSK (D7AF63 ), SFRA_GEOSL (Q74FU6 ), SOEA_ALLVD (D3RNN8 ), TTRA_ARCFU (O30078 ), TTRA_SALTY (Q9Z4S6 ), Y006_METJA (Q60314 ), YJGC_BACSU (O34720 ), YNFE_ECOLI (P77374 ), YNFF_ECOLI (P77783 ), YOAE_BACSU (C0SP82 ), YYAE_BACSU (P37519 )» more
|
| UniProtKB/Swiss-Prot False negative sequences |
1 sequence
NASA_HALMT (I3R634 ) |
| PDB [Detailed view] |
37 PDB
1OGY; 1Q16; 1R27; 1SIW; 1Y4Z; 1Y5I; 1Y5L; 1Y5N; 2FUG; 2JIM; 2JIO; 2JIP; 2JIQ; 2JIR; 2NAP; 2NYA; 2V3V; 2V45; 2YBB; 3EGW; 3I9V; 3IAM; 3IAS; 3IR5; 3IR6; 3IR7; 3M9S; 3ML1; 3O5A; 4HEA; 5O31; 5XTB; 5XTD; 5XTH; 5XTI; 6G2J; 6G72 » more |
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