ProRule PRU01004
General rule information
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| Accession | PRU01004 |
| Dates | 4-APR-2013 (Created)
19-NOV-2022 (Last updated, Version 8) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51669; 4FE4S_MOW_BIS_MGD |
Name | Prokaryotic molybdopterin oxidoreductases 4Fe-4S domain |
| Function | The Mo/W bis-MGD oxydoreductases contains a domain that coordinates a [4Fe-4S] cluster. The cluster is ligated either by four Cys residues or three Cys residues and one His residue. |
| Scope(s) |
Bacteria Eukaryota Archaea Euryarchaeota |
| Example(s) | A8GHJ4 (NAPA_SERP5); |
Propagated annotation
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Keywords
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| Iron | |
| Iron-sulfur | |
| Metal-binding | |
| 4Fe-4S | |
| end case | |
Gene Ontology
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| case <FTGroup:1> | |
| GO:0051539; Molecular function:4 iron, 4 sulfur cluster binding | |
Cross-references
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| PROSITE | PS00551; MOLYBDOPTERIN_PROK_1; 0-1; |
Features
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| From: PS51669 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="4Fe-4S Mo/W bis-MGD-type #" | |||||||||
| BINDING | 8 | 8 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" |
[CH] | 1 | |||||||
| BINDING | 11 | 11 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" |
[C] | 1 | |||||||
| BINDING | 15 | 15 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" |
[C] | 1 | |||||||
| BINDING | 43 | 43 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" |
[C] | 1 | |||||||
Additional information
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| Size range | 33-98 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Archaea [7] Bacteria [217] Eukaryota [18] All [ 242 ]
- Retrieve set of proteins with 3D structure for this domain