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Entry: PS51681

General information about the entry

Entry name [info] SAM_MT_NNMT_PNMT_TEMT
Accession [info] PS51681
Entry type [info] MATRIX
Date [info] 01-JUL-2013 CREATED;
01-JUL-2013 DATA UPDATE;
16-OCT-2019 INFO UPDATE.
PROSITE Doc. [info] PDOC51555
Associated ProRule [info] PRU01018

Name and characterization of the entry

Description [info] SAM-dependent methyltransferase NNMT/PNMT/TEMT-type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=254;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=249;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.2749054; R2=0.0090872; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=686; N_SCORE=9.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=355; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-30; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='A';  M=  22, -89, -19,  -9, -92,   2, -22, -84,  12, -86, -28, -71,  -3, -24,  10, -21, -15, -20, -95, -84;
/M: SY='D';  M=  -6, -90,  32,  29, -19, -34,  10, -87, -23, -40, -80, -29, -82,  -8, -74,   2, -27, -84, -89,  12;
/M: SY='Y';  M=  13, -88,  10,   5,  -9, -82, -73, -75,  -8, -56, -76,  -9, -85,  -9, -52, -15, -16,  -3, -83,  33;
/M: SY='Y';  M= -26,   2,  18, -19, -12, -51,  48, -82, -73, -78,   5, -34, -14,   5, -39, -46, -77, -83, -72,  69;
/M: SY='W';  M= -20, -20,   8,  -8, -36, -47, -29, -78, -41, -49, -76, -37, -88,  11, -13, -46, -37, -13,  93,  39;
/M: SY='D';  M= -57, -92,  54,  18, -95, -81,   4, -51,   8, -91, -84,   5, -81,  14,   3,   0, -41, -61,-101, -81;
/M: SY='E';  M= -75, -91,  18,  31, -85, -23,  25, -84,   2, -25, -77,  -4, -82,  -8,   3,  -1, -46, -32, -94, -16;
/M: SY='F';  M= -51, -88, -96, -25,  95, -94, -82, -65, -88, -59,   0, -90, -96, -93, -88, -51, -81, -41,  58, -13;
/M: SY='D';  M= -76, -90,  72,  -9, -56, -54,   6, -51, -25, -45,  -1,  31, -26,  -4, -40, -15, -69, -85,-100, -32;
/M: SY='P';  M= -23, -93, -21, -68, -89, -78, -17, -80, -44, -88, -79, -75,  90, -73, -21,  15, -18, -25, -91, -23;
/M: SY='R';  M= -30, -12,  24,  27, -41, -82, -69, -84,  20, -18, -76, -11, -80,  10,  30, -24, -19, -82, -13, -77;
/M: SY='A';  M=  43, -83,  27,  -1, -84, -29, -14, -78, -25, -43, -76, -21, -80, -25, -41,  -1, -39, -19,  11, -29;
/M: SY='Y';  M= -83, -93, -84, -50,  20, -49, -54, -69, -46, -33, -63, -84, -95, -75, -76, -79, -78, -74, -44, 112;
/M: SY='L';  M= -49, -84, -46, -85,  25, -95, -19,   7, -44,  52,  -9, -88, -93, -31, -47, -84, -74,   5, -82, -62;
/M: SY='D';  M=   3, -22,  53,  14, -92, -43, -69, -88,   1, -60, -81, -10, -79,  17,   9,  -9, -35, -53, -97, -81;
/M: SY='H';  M= -33,   8,  -9,  -5, -15, -45,  52, -48,  -2, -60, -36,  -5, -81,   9,  -5, -17,  26, -34, -91, -16;
/M: SY='Y';  M= -47, -11, -40, -78,  40, -53, -20, -72,  -3, -39, -69,  47, -91, -31, -72, -72, -73, -42,  11,  72;
/M: SY='Y';  M= -82,  -3, -86, -84,  28, -91, -59, -65, -35, -18, -24, -84, -94, -26, -42, -80, -77, -22,  34, 100;
/I:         I=-33; MI=0; MD=-84; IM=0; DM=-84;
/M: SY='T';  M=   7, -13,  -7,  -5, -85, -52, -28, -78,  -6, -58, -24,  -2, -16, -65,   5,  26,  34, -28, -95, -79;
/M: SY='D';  M= -74, -87,  30, -41,  21, -33, -12, -74, -12, -20, -18,  10,  27, -28, -41,  -6,   6, -32,  11, -27;
/M: SY='P';  M= -21, -22,   3, -10, -74, -37,   8, -28, -23,  12,  20, -30,  28, -30, -19, -21, -39, -16, -13, -24;
/M: SY='R';  M= -47, -88,  15,  19, -83, -23, -31, -50,   8, -55, -78, -29,  -9, -21,  28,  28, -16, -81, -88,   2;
/M: SY='D';  M=  10,  18,  19,   9, -80,  10, -76, -28, -14, -42, -21, -68, -13, -70, -56, -19,  -3,  -9, -89,  -7;
/I:         I=-14; MD=-34;
/M: SY='D';  M= -77, -93,  68,  15, -90, -49,   7, -88, -41, -34, -25, -32,  36, -29, -22, -26, -28, -87,   6, -79; D=-14;
/I:         I=-14; MD=-34;
/M: SY='D';  M= -29, -87,  40, -35,   4, -18,   8, -19, -11, -15, -16, -31, -46, -31, -15, -31, -37,   3, -88, -10; D=-14;
/I:         I=-14; MD=-34;
/M: SY='A';  M=  21,   5, -25, -15,  -4, -24, -77, -26,  -8,  -1, -22, -29, -23,  -9,  -2, -23, -21, -30, -87, -74; D=-14;
/I:         I=-14; MD=-34;
/M: SY='E';  M= -57,-103, -10,  32, -98, -58,   0, -53, -34, -65, -26, -32, -17, -32,  -9, -40,  -8, -36,   9, -90; D=-14;
/I:         I=-14; MD=-34;
/M: SY='R';  M= -61, -42, -35,  -7,-107, -25, -94, -10, -28,-100, -18, -11,  -9, -36,  -2, -20, -59, -94,-113,-102; D=-14;
/I:         I=-14; MI=0; MD=-34; IM=0; DM=-34;
/M: SY='I';  M= -60, -19, -53, -29,  15, -36, -86,  30, -83,  -3, -30, -86, -36, -37, -21, -28, -75,  21,  20,  -8; D=-14;
/I:         I=-14; DM=-34;
/M: SY='M';  M= -51, -16, -46, -48,  -4, -64,   8,  17, -76,   5,  48, -80, -11, -45,   3,  -3, -71,   5, -87, -30; D=-14;
/I:         I=-14; DM=-34;
/M: SY='H';  M= -27, -13, -10,  -7, -40, -47,  49, -55,  16, -14,   0, -44,  11,   8,  18, -19, -21, -78, -89, -33; D=-14;
/I:         I=-14; DM=-34;
/M: SY='W';  M= -75,  -8, -17, -44,  50, -28,  17, -12, -41,   3, -62, -74, -29,   6,   6, -24, -38, -32,  50,  10; D=-14;
/I:         I=-14; DM=-34;
/M: SY='P';  M= -37, -83, -73, -39,  -3, -80,  26,  16, -11, -19,  16,  16,  35,  18, -50, -32,   4,   4, -85, -34;
/M: SY='M';  M= -28, -81, -85, -76,   8, -38, -15,  -6, -71,  43,  45, -79, -86,  18,  14, -76, -70,   5, -79, -27;
/M: SY='H';  M=   0, -85,  11,  18,  10, -21,  25, -41,  19, -29, -69, -37, -27,  17,  10, -65, -21, -49,  -8, -15;
/M: SY='F';  M= -18,  20, -67,  11,  38, -43,   7, -70,  13, -24, -21,  25, -34, -26,  -4, -30,  -8, -25, -78,  -8;
/M: SY='F';  M= -75, -35, -43, -81,  61, -49,   3,  -3, -56,  44, -50, -81, -89,  -8, -80, -78, -19,  -8, -70, -11;
/I:         I=-38; MD=-97;
/M: SY='H';  M= -14, -84, -70, -18,  -3, -79,  92, -41, -44, -16, -26, -64, -11, -63,   8,   6,  -2, -42,   5,   3; D=-38;
/I:         I=-38; MI=-97; MD=-97; IM=-97; DM=-97;
/M: SY='K';  M= -18, -10,  13,  15, -28,   8, -21, -49,  22, -79,  -4, -11, -15,  21,  -3,   8, -39, -45, -85, -30; D=-38;
/I:         I=-38; DM=-97;
/M: SY='T';  M=  -1, -18, -41, -74,  13, -48, -73,  30, -39,  -4, -59,   2, -79,  -9, -41,   5,  38, -36, -79,   2; D=-38;
/I:         I=-38; DM=-97;
/M: SY='F';  M=  -8,  21, -36, -25,  81, -52, -73,  -9, -76,   3, -22, -75, -45,  18, -77, -34, -33, -36, -64, -45;
/M: SY='S';  M=   7,  26, -67,   4, -14, -42,   4, -13, -37, -27, -21,  -4,  17,  10, -70,  31,   2, -44, -80,  13;
/M: SY='S';  M=   2, -77, -16, -19, -31,   2, -70, -71, -16, -27, -20,  -9,  12, -26, -15,  51,  -6, -17,   6, -72;
/M: SY='G';  M= -14, -82,   6,  10, -81,  55, -71, -30, -40, -26,   2, -24,  15, -64,  10, -18, -67, -27, -84, -77;
/M: SY='P';  M= -42, -83,  16, -43, -77,  25, -18, -14,   8, -17, -67, -27,  41,  21,   7,  14, -28, -46, -82, -25;
/M: SY='V';  M= -25, -77,  14,   0,  13, -20,   2,  19, -11,  -7, -57, -65, -77, -66, -15,  14, -30,  34, -82, -62;
/M: SY='K';  M= -44, -81, -32, -18, -81,   1,  20, -82,  53, -80, -70,   2, -25,  25,  36,   0,  23, -77, -83, -35;
/I:         I=-45; MI=0; MD=-115; IM=0; DM=-115;
/M: SY='G';  M= -57, -81,  11, -35, -82,  78, -72, -46, -28, -82, -75, -55,  -9, -66,  -5,  -1, -29, -20,   2, -77;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='D';  M= -15, -83,  44,  30, -77, -33, -65, -41,  -3,  -2, -13,   0, -76, -11,  20, -29, -24, -30, -87, -21; D=-31;
/I:         I=-31; DM=-79;
/M: SY='T';  M= -64,   2, -40, -64, -38, -76, -68, -20,   1, -18, -63,  11, -75,   1,  45,   5,  55,   1, -87, -69; D=-31;
/I:         I=-31; DM=-79;
/M: SY='L';  M= -69,  16, -87, -83, -14,   8, -76, -13, -82,  64,  22, -82, -87, -77, -81, -77, -68,  13, -78, -30; D=-31;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='L';  M= -18, -75, -88, -81, -49, -87, -77,  54, -80,  64,  23, -83, -83, -75, -80, -76, -64,   4, -77, -59;
/I:         I=-45; MD=-115;
/M: SY='D';  M= -70, -85, 104,  41, -91, -71,  -9, -90, -57, -87, -85, -43, -69, -54, -65, -31, -62, -86,-102, -75; D=-45;
/I:         I=-45; MI=-115; IM=-115; DM=-115;
/M: SY='I';  M= -66, -76, -87, -83,  32, -89, -78,  58, -80,  20, -43, -81, -82, -79, -80, -74, -28,  52, -70,  26;
/M: SY='G';  M= -53,  28, -28, -76, -85,  91, -74, -91, -72, -87, -78, -54, -72, -69, -79,   9, -35, -84, -80, -80;
/M: SY='C';  M=  38,  85, -69, -68, -73, -25, -31, -41, -68, -22, -65, -59, -73, -65, -73,  48,  38, -36, -87, -72;
/M: SY='G';  M= -39, -80, -67, -79, -86,  99, -74, -94, -73, -89, -78, -26, -72, -70, -80, -52, -71, -87, -77, -81;
/M: SY='P';  M= -11, -89, -69, -59, -87, -69, -72, -76, -66, -85, -73, -72, 117, -68, -77,  -3, -14, -78, -83, -84;
/M: SY='T';  M= -24, -69, -61, -67, -68, -41, -12,   3, -64, -61,  -8,  53, -71, -64, -70,  18,  65,  37, -90, -68;
/M: SY='I';  M= -66, -77, -34, -79, -15, -88, -82,  71, -78,  26, -42, -79,  21, -77, -81, -73, -22,  39, -79, -61;
/M: SY='Y';  M= -47,   8, -70, -71, -38, -49,  72, -11, -68, -29,   6, -35, -81, -18, -66,  -7, -65, -24,   7, 102;
/M: SY='Q';  M= -62,   3, -61, -30,   0, -47,  24, -68, -59, -31, -63,  36,  50,  61, -62,  34, -57, -18, -75,  21;
/M: SY='L';  M=  28, -72, -50, -72, -58, -75, -29,  10, -73,  47, -13, -30,   6, -70, -75, -12, -18,  31, -81, -64;
/M: SY='L';  M= -47,  12, -87, -81,  24, -87, -73,  49, -79,  57,  38, -81, -83, -75, -79, -45, -64, -11, -70,  -3;
/M: SY='S';  M=   4,  25, -65, -63, -73, -60, -67, -67, -64, -13, -66, -55,  20, -59, -69,  82,  20, -25, -85, -70;
/M: SY='A';  M=  77, -67, -75, -68,  17, -28, -71, -33, -69,  -9,  49, -68, -73, -66, -72, -51, -12, -53, -75, -63;
/M: SY='C';  M=  -7,  71, -68, -65, -71, -36, -68, -67, -61,   5, -63, -59,   4, -26,  19,  63,  12, -38, -85, -70;
/M: SY='P';  M= -37, -82,   1,  45, -82, -72, -60, -80,  38, -54, -20,   3,  49, -48,  47,  -1, -38, -77, -82, -73;
/M: SY='W';  M=  -7,   8, -71, -67,  29, -72,  46, -41,  -8, -64, -61, -23, -77, -27,  20,  23, -19,   4,  77,  48;
/M: SY='F';  M=  34,  45, -81, -77,  87, -73, -73,  -8, -75, -53, -57, -72, -81, -78, -76,   1, -30,  -2, -60, -20;
/M: SY='Q';  M= -39, -81,  11,  30, -84, -70, -57, -82,  45, -80, -70,  19,  -7,  49,  44,   8, -29, -78, -82, -70;
/I:         I=-45; MD=-115;
/M: SY='E';  M= -39,  23,  39,  57, -81, -47,  23, -83, -19, -79, -15,  44, -69, -18,  16,  15, -59, -78,  -1, -70; D=-45;
/I:         I=-45; MI=-115; IM=-115; DM=-115;
/M: SY='I';  M= -41, -78, -87, -84, -52, -90, -11,  96, -80,  -9,   0, -78, -77, -76, -83, -74, -61,  18, -78, -59;
/M: SY='V';  M= -62, -74, -10, -22, -52, -81,  43,  30, -70,  -8, -49, -66, -76, -68, -72, -62,  38,  56, -74,  48;
/M: SY='C';  M=  -2,  58, -82, -76,  11, -57,  -9, -26, -76,  57,  47, -75, -82, -72, -75, -21, -33,  11, -76, -57;
/M: SY='S';  M=  48,  11, -67, -65, -67, -33, -68, -62, -64,   0, -60, -59, -70, -61, -36,  53,  37, -22,  12,  -6;
/M: SY='D';  M= -67, -84,  91,  67, -87, -71,  -5, -87,  -4, -83, -80, -46, -65, -19, -58, -59, -62, -83,  -9, -72;
/M: SY='Y';  M= -71, -15, -75, -74,  43, -80,  29, -20, -69,  -4, -51, -72,   4, -67, -32, -24, -66, -26, -43, 105;
/M: SY='T';  M=  12,  21, -42, -67, -25,  -1, -17, -53, -67,  16, -11, -33, -72, -29, -71,  37,  45,  19, -83, -65;
/M: SY='P';  M=  10, -80,  32,  46, -82, -68, -61, -76, -11, -44, -70,  10,  65,  26, -34, -21, -12, -74, -83, -40;
/M: SY='Q';  M=   7, -10, -36,   6, -80,   1,   4, -76,  -3, -55, -66,  19, -33,  64,  29,  35, -57, -38, -81, -68;
/M: SY='N';  M= -30,  50, -23, -41, -79, -12, -52, -79, -55, -83, -72, 105,  -9, -56, -63,  11, -23, -77, -95, -75;
/M: SY='R';  M= -66,  26, -72, -64, -64, -82, -27,   9, -22,  14, -53, -35, -80, -18,  81, -66, -33,  24, -79, -25;
/M: SY='E';  M=   9, -78,  29,  52, -76, -26,  33, -71, -18,  -4, -19, -56, -68,  39,   7, -16,  -4, -46, -83, -66;
/M: SY='W';  M=  11, -79, -27,  78, -67, -73, -63, -20, -32, -46, -16, -33, -66, -49, -61, -21, -14,  -8,  81,   9;
/M: SY='L';  M= -44, -73, -85, -78, -13, -45, -75,  34, -78,  64, -17, -81, -40, -24, -77, -74, -62,  34, -75, -31;
/I:         I=-23; MD=-58;
/M: SY='E';  M= -66, -83, -27,  60, -78, -55, -14, -46,  31, -54, -68,  14, -69,  50,  34, -25, -34, -77, -17,  -4; D=-23;
/I:         I=-23; MD=-58;
/M: SY='K';  M=  -5, -80, -29, -52, -79, -16, -61, -76,  73, -24,   9,  -8, -71,  28,  36, -22, -62, -73, -79, -69; D=-23;
/I:         I=-23; MD=-58;
/M: SY='W';  M= -84, -23,-109, -87, -51, -83,-109, -83, -80, -80, -82,-102, -88, -24, -84, -89, -60, -96, 167, -38; D=-23;
/I:         I=-23; MI=0; MD=-58; IM=0; DM=-58;
/M: SY='L';  M= -32, -83, -93, -84, -34, -95, -83,  -4, -14,  59, -12, -89, -92, -27, -81, -83, -42,   2,  -1, -68; D=-23;
/I:         I=-23; DM=-58;
/M: SY='N';  M=  -1, -14,  11,  17, -78, -36,   6, -40,  33, -53, -67,  49, -35,  13,  32,  -7,  -2, -47, -84, -69;
/M: SY='K';  M= -40, -76,  25,  27, -79,   1,  11, -72,  54, -76, -69,  38, -68, -50, -12,   6, -14,   1, -85, -69;
/M: SY='E';  M=  12, -78,  48,  50, -82,   5,  11, -47, -20, -76, -12,  13, -67,  21,  -4,  -9, -13, -73, -86, -70;
/M: SY='P';  M= -36, -84,   5,  23, -80, -49, -12, -39,  -3, -48, -66, -64,  89,  10, -16, -36,  -1,  -1, -83, -74;
/M: SY='D';  M= -18, -78,  64,  10, -40,  51, -63, -52,  -8, -38, -73, -29, -69, -21, -65,  16, -29, -75, -82, -26;
/M: SY='A';  M=  68,  23, -67, -33, -73,   5, -68, -48, -39, -35, -26, -22, -71, -60, -10,  29, -31, -25, -79, -24;
/M: SY='F';  M= -42, -76, -38, -73,  79, -51,  46,   6, -39, -38,  17, -68,   3, -71, -39,   1, -34,  -3,  18,  31;
/I:         I=-29; MD=-75;
/M: SY='D';  M= -45, -83, 103,  -9, -37, -20, -59, -83, -59, -39, -80,   5, -28, -29, -67, -37, -61, -82,  10, -70; D=-29;
/I:         I=-29; MI=0; MD=-75; IM=0; DM=-75;
/M: SY='W';  M= -76, -98, -98, -81, -21, -45,   6, -71, -74, -37, -11, -91, -81, -73, -76, -81, -85, -55, 167,  18;
/M: SY='S';  M= -39, -70,  24, -27, -74, -40, -63, -67, -57, -26, -66, -50, -68,   1,  -3,  74,  46, -16, -86, -68;
/M: SY='P';  M= -22,  21, -65, -16,   7, -69,  33, -25, -36, -40, -31,  -3,  90, -63, -70,  18,   4, -69, -81, -67;
/M: SY='F';  M= -14, -75, -76, -73,  66, -78,  13, -13, -38, -28,  10, -70, -12, -69,  -8, -20,  16,  18,  15,  55;
/M: SY='W';  M=  13,  11, -37, -73,  41, -74, -74,  20, -72,  13, -17, -71, -78, -24, -74,  18, -16,  15,  79, -11;
/M: SY='K';  M= -37, -80, -10,  44, -79, -44, -59, -48,  62, -23, -65, -54, -24,  55,  -1, -23,   1, -72, -79, -68;
/M: SY='Y';  M= -21, -77, -71, -22,  25, -76,  42, -35, -20, -21,   9, -68, -14, -22, -65, -16,   0,  17,  36,  83;
/I:         I=-45; MI=0; MD=-115; IM=0; DM=-115;
/M: SY='V';  M=  12,  19, -83, -78, -34, -47, -79,  37, -76,  27,  -7, -77, -79, -75, -78, -66, -15,  61, -80, -32;
/M: SY='C';  M=  52,  88, -72, -37, -70, -67, -73, -60, -21, -15, -60, -65, -75, -66,  -1, -15,  18,  13,  -8, -71;
/M: SY='E';  M= -61, -14,  38,  47, -80,  -8, -58, -29, -15, -60, -24,   9, -22,  34,  30,   7,  13, -72, -85, -70;
/M: SY='L';  M= -45, -73, -16, -39, -11, -80,  30,  10, -34,  59,   5,  -9, -78, -65,  -6, -38,  21, -28, -78, -57;
/M: SY='E';  M= -27, -13, -17,  88, -77, -54,  -8, -74, -14,   6, -65, -62,  26, -15, -31, -61, -63, -72, -82, -72;
/I:         I=-38; MD=-97;
/M: SY='G';  M=  14, -78, -26,  29, -84,  80, -69, -84, -65, -83, -74, -25,   7, -61, -72, -31, -65, -47, -79, -78; D=-38;
/I:         I=-38; MD=-97;
/M: SY='Y';  M= -36,   5, -14,  -3,  -6,  16,   3, -20,   6, -48, -14,  38, -24,  -6,  -8,   0,  -8, -68,   0,  58; D=-38;
/I:         I=-38; MD=-97;
/M: SY='R';  M=  13, -16, -65, -39, -74,   3, -63, -72,  19,  -6,   5, -26,  -9, -15,  56,  36, -34, -68, -80, -69; D=-38;
/I:         I=-38; MI=-97; IM=-97; DM=-97;
/M: SY='W';  M=   1,  10,  33,  13, -75,  -6, -65, -70,  -7, -46, -22,  -9,   3,  -6, -30,  34,  16, -13,  48, -68;
/I:         I=-45; MD=-115;
/M: SY='D';  M=  -4, -76,  21,  -2, -74,  -6, -22,   5,   5, -29, -10, -38,   1,   8,   5,  15,  21,  -1, -84, -69; D=-45;
/I:         I=-45; MI=-115; IM=-115; DM=-115;
/M: SY='W';  M=  -8,   8,  18,  20, -69, -20, -69, -50,  18, -31, -69, -29,  11, -19,  -3,  -4,  16, -53, 101, -61;
/M: SY='Q';  M= -13,  -6,  20,  54, -75, -72, -17, -15,   7, -35, -65, -27,  -7,  58, -24, -17,  -3, -44,  33, -30;
/M: SY='E';  M=  -8, -77, -16,  60, -40,  -4,  -8, -67, -14, -10, -64,  -9,  43, -22, -35,  -2,  -4,  -7, -82, -70;
/I:         I=-29; MD=-75;
/M: SY='K';  M=  -1, -21, -63,  23, -73, -45, -16, -19,  49, -32,   7, -62, -34,  -1,  46, -61, -37,  18, -81, -67; D=-29;
/I:         I=-29; MD=-75;
/M: SY='E';  M=  -1, -17, -55,  60, -36, -43, -61, -68, -13,   4,  21, -25, -28,  47,  -4, -10, -30, -45, -81, -68; D=-29;
/I:         I=-29; MI=0; MD=-75; IM=0; DM=-75;
/M: SY='E';  M=  15,  -6,  29,  59, -77, -34, -61, -70, -37,  -4, -20, -22, -33,  25,   6, -22, -18, -31, -84, -71; D=-29;
/I:         I=-29; DM=-75;
/M: SY='R';  M=   2, -19,  -1,   3, -76, -45, -23, -46,  41, -50, -66, -57, -25,  42,  56,   2, -61, -39,  15, -21;
/M: SY='T';  M=   3, -70, -33, -39, -58, -77, -71, -25, -68,  50, -12, -68,  -2, -23, -34, -34,  50,  21, -81, -63;
/M: SY='R';  M= -49, -83, -27, -15, -77, -78, -14, -23,  16, -73, -65, -22, -76, -46,  99, -63, -37, -22, -80, -65;
/M: SY='R';  M=  18, -76,   3,  -2, -79, -10,  25, -72,  22, -74, -66, -54, -70,  32,  42,  32, -35,  -4, -82, -67;
/M: SY='A';  M=  48, -71, -66, -35, -74, -65, -65, -62,  21, -33,  -8, -29, -71,  12,  35,  15,  10,  12, -81, -68;
/M: SY='I';  M= -41, -74, -83, -78, -27, -85, -82,  69, -20, -42,  13, -75, -27, -74, -42, -35, -14,  63, -82, -62;
/M: SY='K';  M= -64,  18, -61, -29, -79, -28, -11, -76,  72, -76, -66, -54, -70,   9,  59, -31,  17, -28, -80, -67;
/I:         I=-45; MD=-115;
/M: SY='Q';  M=  17, -15,  15,  -7, -83,  15,  12, -52,  27, -78, -68,  -7, -25,  57,  23, -14, -30, -74, -82, -70; D=-45;
/I:         I=-45; MI=-115; IM=-115; DM=-115;
/M: SY='V';  M= -36,  -7, -82, -78, -56, -19, -81,  42, -76,  23, -44, -74, -79, -75, -79, -20,   7,  66, -83, -63;
/M: SY='V';  M= -26, -72, -81, -77,  14, -45, -20,  18, -76,  45, -10, -30, -81, -74, -77,  -9, -59,  55, -76, -24;
/M: SY='P';  M= -38, -81, -15, -31,  19, -42,  41, -40,  46, -37, -64,  -2,  69, -58, -14,  -2, -39, -25, -78, -62;
/M: SY='C';  M= -26, 126, -16, -78,  21, -17, -78, -49, -75, -24, -65, -69, -87, -79, -35, -40, -65, -17,  51, -17;
/M: SY='D';  M= -69, -82, 102,   2, -85, -25,  14, -84, -57, -33, -78,  16, -28, -24, -36, -58, -61, -82, -99, -71;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='V';  M= -41,  13, -47, -75, -13, -34, -80,  26, -36,   6,  -4, -77,  25, -24, -42, -70, -59,  67, -83, -64; D=-31;
/I:         I=-31; DM=-79;
/M: SY='H';  M= -28, -12, -34, -37, -36, -39,  68, -43, -19,  12, -57,  10,  -6,   1,   1,  -6,  59, -62, -86, -61;
/M: SY='Q';  M= -12, -79, -13,  29, -15, -11,  16, -72,  35, -11, -63,  23, -70,  57,  13, -25, -61, -36, -79, -64;
/M: SY='P';  M= -10, -79,  34,  35, -31, -51, -62, -77, -17, -50, -71, -29,  54, -19,  27,  27,   9, -73, -83, -71;
/M: SY='W';  M= -66, -81,   9, -14, -40, -15,  11, -77, -58, -49, -70,  69,  60,   4, -33,   2, -59, -79,  79,   4;
/M: SY='P';  M= -46, -83,  20, -32, -76, -44, -72, -35, -66, -25, -24, -68,  99, -67, -75, -11, -19,  23, -85, -76;
/M: SY='L';  M= -41, -74, -34, -22,   3, -84,   8,  41, -73,  54,  31, -35, -80, -26, -40, -72, -22,   7, -76, -56;
/M: SY='G';  M=  12,  -8,  30,   0, -79,  40,  24, -76,  -5, -52,   6, -22,  24,   6, -35,   6, -61, -37, -82, -35;
/I:         I=-17; MD=-42;
/M: SY='P';  M=   2,   8, -32,  19, -43, -68,   3, -74, -12, -56, -69, -30,  67,  -3, -65,  24,  41, -70, -82, -19; D=-17;
/I:         I=-17; MD=-42;
/M: SY='Q';  M= -24, -88,   4,   2, -81,  -4, -75, -29, -28,  -7, -21, -14,  14,  18,   5, -39, -71,  15, -92, -79; D=-17;
/I:         I=-17; MD=-42;
/M: SY='H';  M= -72, -12, -11, -16, -34, -46,  49, -47, -12, -41, -67, -39, -56,  20, -34, -17,  13,  24, -86,  23; D=-17;
/I:         I=-17; MD=-42;
/M: SY='L';  M= -73, -85, -43,  -2, -18, -23, -75, -32, -70,  31, -25,  -9, -87, -16,  15, -17, -44,  11,   6, -10; D=-17;
/I:         I=-17; MD=-42;
/M: SY='P';  M= -28, -93, -30,  14, -49,  14, -77, -51, -22, -22, -77, -74,  67,  -4, -24, -12, -72, -83, -90, -84; D=-17;
/I:         I=-17; MI=0; MD=-42; IM=0; DM=-42;
/M: SY='P';  M= -35, -93, -75, -44, -36, -32, -11, -80,  12, -13, -73, -30,  73,  38, -70, -70,  -3, -81, -89, -80; D=-17;
/I:         I=-17; DM=-42;
/M: SY='F';  M=  33, -82, -89, -84,  68, -82, -74, -42, -41, -62, -21, -83, -90, -82, -81, -72, -73,  -2, -62,  54; D=-17;
/I:         I=-17; DM=-42;
/M: SY='D';  M= -80, -94, 104, -44,-101, -77, -66, -98, -67, -96, -94, -49, -30,  -6, -75, -68, -70, -95,-113, -83; D=-17;
/I:         I=-17; DM=-42;
/M: SY='C';  M= -38,  94, -92, -90, -71, -92, -93,  18, -87, -41, -62, -83, -93, -89, -90, -75,  -3,  51, -99, -30; D=-17;
/I:         I=-17; DM=-42;
/M: SY='V';  M= -70, -82, -97, -91, -25, -99, -94,  37, -89,  15, -51, -91, -92, -89, -90, -82, -67,  68, -92, -70; D=-17;
/I:         I=-17; DM=-42;
/M: SY='I';  M= -70, -82, -86, -86, -25, -48, -82,  36, -83,   9,  -6, -36, -87, -80, -85,   4,  14,  31, -84,  15; D=-17;
/I:         I=-17; DM=-42;
/M: SY='S';  M= -41,  40,  -8, -64, -71, -64, -66, -36, -63, -64,  62, -53, -69, -60, -68,  70,  56, -39, -88, -68;
/M: SY='S';  M=   8,  48, -31, -70,  37, -38, -71,   7, -70,  -3, -26, -22, -76, -67, -73,  51,   9,  -3, -77, -59;
/M: SY='F';  M= -48, -76, -87, -81,  79, -18, -71, -48, -79,  46, -47, -81, -34, -79, -78, -75, -38, -21,  62,  19;
/M: SY='C';  M= -25, 115, -53, -76, -67, -42, -15,   2, -74, -39, -60, -68, -29, -29, -79, -43,  27,  32, -92, -29;
/M: SY='L';  M=  23, -72, -84, -76, -51, -79, -73,   0, -77,  70,   0, -80, -27, -72, -77, -37, -63,   0, -77, -61;
/M: SY='E';  M= -42,  47,  15,  91, -84, -41, -60, -50, -26, -78, -74,  -5, -64, -19, -58, -58,  -8, -76, -87, -76;
/M: SY='S';  M=  27,  38, -69, -69, -34,  -5, -68, -17, -68, -44, -62, -36, -74, -64, -71,  58,   4,  18, -76,  29;
/M: SY='A';  M=  60,  26, -76, -71, -67, -51, -78,  32, -71, -39, -16, -69, -74, -69, -75,  -6,   2,  37, -83, -69;
/M: SY='C';  M=  22,  98, -69, -69, -33, -64, -72, -35, -68, -70, -67, -22, -75, -66, -73,  59,  24, -14, -89, -72;
/I:         I=-42; MI=0; MD=-106; IM=0; DM=-106;
/M: SY='K';  M= -26, -32, -39,  36, -80, -30,   4, -76,  45, -34, -68,   4,  35,  12, -34,  15,   6, -41, -84, -72;
/M: SY='D';  M= -44, -77,  80, -48, -39, -42, -10, -80, -58, -81, -76,  34, -28, -23, -16,  16,  44, -75, -96, -71;
/M: SY='H';  M= -67, -13, -23,  17, -63, -81,  34,  14,  -8,  21, -11, -35,  15, -34,  26, -29, -31,  10, -81, -10;
/M: SY='D';  M=  30, -78,  57,  53, -85, -21, -63, -80,  -8, -79, -15, -34,  -8, -23, -62,  -7,  -5, -73, -88, -75;
/M: SY='E';  M= -10, -78,  15,  72, -81, -43, -62, -39, -29, -75,   6, -31, -26, -17, -61,  27,  28, -70, -86, -74;
/M: SY='Y';  M= -45, -83, -78, -79,  64, -82,  -5, -60, -71, -55, -56, -76, -87, -70, -35, -71, -31, -64,  19, 111;
/M: SY='R';  M= -23,  45, -39,   5, -35, -31,   6, -39,  21, -51, -20, -24, -32,   6,  49,  11,  10, -24, -82, -29;
/M: SY='R';  M=  27, -26,  -9,  -2, -74, -48,  -9,  -2,  30, -26,   6,  20, -29, -54,  42, -13,  -7, -63, -82, -68;
/M: SY='A';  M=  63,  26, -68, -66, -69, -40, -68, -16, -66, -12, -20,  29, -30,  -2, -70,  -8, -30,   1, -79,  -2;
/I:         I=-25; MD=-63;
/M: SY='V';  M= -63,  30, -87, -81, -22, -88, -80,  -7, -80,  44,  28, -82, -85, -78, -80, -43, -21,  64, -84, -62; D=-25;
/I:         I=-25; MI=-63; MD=-63; IM=-63; DM=-63;
/M: SY='K';  M=  15,  20, -21, -14, -83,  -1, -63, -83,  49, -81, -71,  20, -73,   5,  47,  -4, -39, -76, -83, -73; D=-25;
/I:         I=-25; DM=-63;
/M: SY='N';  M= -38,   8, -52, -57, -80, -42,  -1, -81,  35, -59, -70,  85, -75, -21,  50, -17, -30, -78, -88, -71; D=-25;
/I:         I=-25; DM=-63;
/M: SY='F';  M= -24, -74, -86, -81,  41, -85, -77,  37, -79,  35,  40, -79, -82, -77, -79, -41, -18,  41, -73, -53; D=-25;
/I:         I=-25; DM=-63;
/M: SY='S';  M=  29,  26, -72, -70, -27,  16, -14, -19, -69, -10,   4, -63, -74, -20, -73,  30,  23,  22, -83, -68; D=-25;
/I:         I=-25; DM=-63;
/M: SY='S';  M=  -9, -11,  19, -34, -81,  11, -23, -80,   1, -81, -73,  21, -28, -55,  30,  54,  14, -74, -87, -72; D=-25;
/I:         I=-25; DM=-63;
/M: SY='L';  M=  17,  27, -81, -72, -30, -79,   2, -47, -74,  65,  14, -77, -31,  20, -73, -69, -66, -51,  -1,  -9; D=-25;
/I:         I=-25; DM=-63;
/M: SY='L';  M= -46, -73, -87, -81, -25, -88, -77,  16, -81,  70, -37, -84, -85, -76, -80, -43, -63,  38, -78, -59; D=-25;
/I:         I=-25; DM=-63;
/M: SY='K';  M= -67, -82, -60, -14, -80, -29, -22, -82,  81, -53, -18,  -9, -71, -45,  61, -39, -63, -78, -79, -68; D=-25;
/I:         I=-25; DM=-63;
/M: SY='P';  M= -48, -89, -34, -23, -83, -73, -71, -39, -10, -36, -69, -71, 108, -30, -12, -36, -19, -36, -83, -80; D=-25;
/I:         I=-25; DM=-63;
/M: SY='G';  M= -54, -80, -66, -49, -86,  95, -72, -93, -68, -89, -78, -24, -72, -67,  -3, -32, -70, -87, -78, -80;
/M: SY='G';  M=  19, -78, -68, -77, -85,  93, -74, -90, -72, -86, -76, -55, -71, -69, -79, -51, -69, -81, -77, -80;
/M: SY='H';  M= -68, -82, -68, -65,  14, -13,  86, -26, -20, -13, -12, -62,  41, -27,  -1, -25,   0, -40,  12,  45;
/M: SY='L';  M= -72, -74, -89, -81,  52, -89, -72, -20, -81,  77, -36, -86, -47, -77, -79, -80, -68, -46,  10, -47;
/M: SY='I';  M=  13, -11, -85, -80, -10, -57, -80,  55, -78,  31,  11, -79, -80, -76, -80, -70, -60,  46, -79, -60;
/M: SY='M';  M=   1, -74, -83, -75,  13, -80, -68,  19, -74,  46,  74, -76, -79,  -6, -73, -69,  -8, -11,  10,   6;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='M';  M=  35,  29, -71, -71, -31,  15, -27,  22, -68, -49,  48,  15, -75, -13, -72,  -8,  -8,  14, -80, -26;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='G';  M=   3, -24, -28, -51,  28,  68, -71, -68, -71, -48, -67, -59, -74, -69, -76,  12, -11,   4, -72,  -2;
/M: SY='M';  M=   5,  13,  -1, -48, -60,  -3, -71,   9, -71, -51,  66, -67, -76, -69, -74, -12,   2,  49,  12,  14;
/M: SY='L';  M= -26, -76, -74,   8,  -9,  -4, -70,  22, -10,  55, -45, -73, -78, -65, -33, -25, -20, -49,  10,   4;
/M: SY='N';  M= -14, -78, -10,  34, -82,  51,  -6, -82, -26, -51, -72,  62, -71, -17,  13, -54, -32, -55, -85, -74;
/I:         I=-42; MI=0; MD=-106; IM=0; DM=-106;
/M: SY='S';  M=  21,  11,  -6,  19,  -6, -13, -65, -27, -30, -30,  28, -31,  -8,  19,   5,  28, -33, -12, -80, -66;
/M: SY='T';  M= -36, -71,  -1, -33, -75, -65,   4, -38,  -5, -71, -12,  30,  -9,  -2, -33,  47,  62, -13, -89, -69;
/M: SY='H';  M= -47, -10, -34, -41,  45,  35,  57, -39, -69, -66, -64, -60, -76, -34, -70,  23,   4, -70,  57,  49;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='Y';  M= -47,  45, -75, -44,  22, -80, -48, -35, -70, -45, -56, -29, -86, -67, -69, -39, -68, -64,  40, 116;
/I:         I=-42; MI=0; MD=-106; IM=0; DM=-106;
/M: SY='M';  M= -45, -75,  -9,  17,  -3, -73, -63,  -8, -24, -24,  46,  11, -34, -58,  25,  14,  33,  -7,  32,  -7;
/M: SY='V';  M=   4, -73, -34, -76,  26,   0, -23,  15, -57, -19, -51, -72, -79, -75, -77, -23, -27,  66,   9, -19;
/I:         I=-45; MI=0; MD=-115; IM=0; DM=-115;
/M: SY='G';  M= -54, -12, -32, -74, -39,  88, -71, -84, -20, -84, -75,   2, -73, -67, -39, -13, -67, -26, -79, -77;
/M: SY='G';  M=   4, -78,  16,  14, -80,  42,  -9, -80,   7, -51, -71,  35,   0,   9, -10, -37,   6, -76, -82, -25;
/M: SY='H';  M= -21, -79, -27,  15, -72,  -4,  68, -40,  14, -35, -61,  -1, -72,  41,  23, -58,  -3,   9, -82,  -8;
/I:         I=-45; MI=0; MD=-115; IM=0; DM=-115;
/M: SY='K';  M= -25, -80,  18, -10, -12, -72, -16, -76,  58, -75, -25, -29,   9, -11,  43,   8, -34, -44, -75,  11;
/I:         I=-45; MI=0; MD=-115; IM=0; DM=-115;
/M: SY='F';  M= -75, -76, -86, -82, 101, -85,   4, -11, -79, -12, -52, -77, -36, -83, -77, -74, -17, -15,  21,  36;
/I:         I=-31; MD=-79;
/M: SY='P';  M= -24, -83,  -8, -34,   7, -25,  61, -75, -62, -57, -13,  -7,  73, -33,  -4,  14, -11, -75, -78,  13; D=-31;
/I:         I=-31; MD=-79;
/M: SY='C';  M=  34,  90, -73, -42, -30,  -7,  20, -35, -70, -14,   7, -30, -78, -69, -39,  10,   1, -19,  -9, -69; D=-31;
/I:         I=-31; MD=-79;
/M: SY='L';  M= -29,  34, -20, -75,   1, -57,  19, -26, -77,  51, -46, -75, -29, -74, -77, -19, -19,  34, -80, -25; D=-31;
/I:         I=-31; MD=-79;
/M: SY='P';  M=  -9,  34, -39, -20, -73, -39,   5, -76,  23, -59, -69,  24,  51, -59,  -3,  20,   8, -54, -80,  22; D=-31;
/I:         I=-31; MD=-79;
/M: SY='L';  M= -68,  12, -84, -79, -22, -27, -75,  20, -77,  54,  15, -79, -17, -15, -37, -24, -34,  16, -79, -24; D=-31;
/I:         I=-31; MI=-79; MD=-79; IM=-79; DM=-79;
/M: SY='D';  M= -62, -76,  53, -22, -82,   3,  -9, -78, -18, -79, -14,  44, -70,  -3, -15,  16,  50, -74, -93, -72; D=-31;
/I:         I=-31; DM=-79;
/M: SY='E';  M= -34, -81, -22,  75, -38, -45, -61, -77,  23, -53,  20, -60, -42,  -5,  13,  -4,  -6, -53, -82, -71;
/M: SY='E';  M=  14, -79,  37,  63, -39, -29, -61, -80, -54, -79, -74,  18, -27,   9, -27,  10, -17, -43, -87, -74;
/M: SY='F';  M= -16, -76,  23,  16,  50, -77,   9, -13, -66, -20,  19, -11, -76,  -9, -70, -18,  17,  11, -73,  -5;
/M: SY='V';  M= -64, -75, -37, -42, -54, -60, -79,  39, -78,  34,  29, -80, -82, -76, -79, -43, -61,  61, -82, -19;
/M: SY='R';  M= -26, -22, -64,  26, -29, -50, -63, -28,  22,   5, -60,  -8, -76,  -5,  58, -66, -65,   1,   9,  -4;
/M: SY='Q';  M=  15, -12,  17,  36, -84, -50, -61, -78,  32, -53, -69, -17, -70,  56,  14,  -3, -35, -42, -83, -72;
/M: SY='A';  M=  60,  14, -70, -34, -74, -26, -73, -11, -67, -35, -16, -31, -73, -29, -40,  32,   1,   6, -84, -72;
/M: SY='L';  M= -26, -75, -86, -80,  22, -86, -75,   9, -78,  62,  10, -37, -33, -75, -34, -51, -65,  21, -75, -56;
/M: SY='Q';  M=   1, -79, -17,  34, -80,  -2, -63, -74,  20, -42, -20, -34, -70,  41,  27,  13,   2, -22, -83, -71;
/M: SY='E';  M=   4, -80,  40,  55, -82, -28, -27, -80,  16, -34, -26,  21,  -6, -51,  -1, -18, -31, -76, -87, -74;
/M: SY='A';  M=  55,  35, -66, -18, -38, -20, -68, -39, -63, -28,   5,  29, -74, -62,  -2,  13,   0, -36, -84, -72;
/M: SY='G';  M= -11, -79, -37, -72, -84,  81, -71, -86, -36, -57, -75,   9, -29,  -7, -47, -53,  14, -80, -81, -79;
/M: SY='F';  M= -72,  39, -80, -45,  71, -83,  10, -33, -40,  12,  20, -73, -84, -32, -34, -40,   8, -34, -58,  53;
/I:         I=-16; MD=-40;
/M: SY='D';  M= -20, -77,  27,  22, -16, -25, -14, -38, -10,   2, -62, -60, -73, -27,  -1,   9,  27,   9, -83, -22; D=-16;
/I:         I=-16; MD=-40;
/M: SY='V';  M= -65, -77,  33, -72, -11, -41, -79,  42, -76,  10, -14, -34, -81, -76, -80, -70, -12,  57, -86, -64; D=-16;
/I:         I=-16; MD=-40;
/M: SY='V';  M= -33, -23,   9,  17, -68, -79, -70,  14,  15,  12, -56, -20, -75,   6, -17, -18,  13,  24, -86, -69; D=-16;
/I:         I=-16; MD=-40;
/M: SY='E';  M= -48, -87,   8,  35, -10, -83, -18, -37,  17, -17, -13,  -2, -79, -36,  23, -38, -18, -24,   4, -29; D=-16;
/I:         I=-16; MD=-40;
/M: SY='W';  M= -43, -31,  -7, -46,  24, -91,  -3, -13, -52,  10,  26, -84, -92, -81, -84, -19, -55, -21,  75,  15; D=-16;
/I:         I=-16; MD=-40;
/M: SY='E';  M= -50, -91, -28,  33, -49, -32, -17, -50,  10, -34, -79,   1, -82, -19,  27,  10, -32, -58, -95, -80; D=-16;
/I:         I=-16; MI=0; MD=-40; IM=0; DM=-40;
/M: SY='H';  M= -24, -87,   0, -22, -12, -59,  31,  21,  -4,  -7, -64, -71,  -7,  -3, -27, -23,  -2, -22,  -5, -29; D=-16;
/I:         I=-16; DM=-40;
/M: SY='S';  M=   0, -80, -25,   2, -41, -42,  18,   2, -13, -21,  -3, -31,  -4,  11,  17,  19,  11, -19, -86, -69; D=-16;
/I:         I=-16; DM=-40;
/M: SY='P';  M=   2, -20,  15,  10,  -7, -20, -18, -50,  -9, -52, -71,  22,  26,  -1,  21,   7, -17, -45, -84, -38; D=-16;
/I:         I=-16; DM=-40;
/M: SY='R';  M= -37,   3,  22,   8, -48, -28, -63, -43,  10,  -9, -32,  14, -35,  20,  33, -17,   2,   3, -84, -38;
/M: SY='R';  M=  10, -79,  18, -17, -11, -27,   4,   1,  16, -50, -22,  -3,  17, -21,  30,   5, -43, -25, -81, -27;
/M: SY='Y';  M=   6, -15,  11,  25,   7, -51,   6, -45, -26,   3, -61, -10,  -6, -60, -17,   3,  -2, -49, -71,  45;
/M: SY='H';  M= -37,  -9,   8,  18,   8, -22,  44, -29, -22, -49, -67,  15,  10,  34, -64,  20,   0, -26, -84, -64;
/M: SY='S';  M=   5,   7,  22,  14, -11, -50,  -7, -73, -32, -27, -18, -36,  23, -61,  -3,  26,  12, -49, -81,  10;
/M: SY='D';  M= -19,   6,  26, -65, -38, -16, -68, -10, -20,  15, -13,  17,  -5, -21, -71,  14,  15, -16, -84,  -9;
/M: SY='R';  M= -47,  -6, -24, -14, -17, -54, -67,   2, -31,   7, -34,  -1, -14,  12,  39, -14,  17,  -5, -80,  -2;
/M: SY='S';  M= -18,  25,  14,   4, -16, -40, -15, -26, -40, -55, -70,  -3,  36, -63, -35,  37,   7, -30,  -7,  13;
/M: SY='D';  M= -48, -11,  73,   5, -86,  30, -64, -16, -63, -58, -78,  25, -17, -11, -39,  -7, -63, -78, -94, -77;
/M: SY='Y';  M= -24, -13,   3, -71,  -4, -39,  29, -21, -71, -27, -61,  -7,   0, -68, -73,  -8,   0,   1,  27,  79;
/M: SY='E';  M= -38, -80,  29,  38, -14, -41, -64, -44,  11, -33, -71,  -2, -15,  12, -29,  20,  28, -72, -85, -42;
/M: SY='G';  M=  20, -77, -47, -68,   9,  52, -12, -78,  14, -57, -21, -25, -75, -34, -13,  28, -63, -48, -79, -69;
/M: SY='M';  M= -22, -26, -84, -80,  24, -83, -69,  32, -38,  15,  78, -19, -82, -72, -75, -37, -46,   4, -70,  34;
/M: SY='F';  M= -31,  -3, -87, -82,  71, -48, -12,  19, -76,  14,  -9, -79, -87, -79,  -8, -45, -35,   6, -64,  14;
/M: SY='F';  M= -74,  33, -87, -84,  75, -88,  -7, -11, -80,  18,   2, -36, -90, -82, -50, -60, -69,  15, -61,  36;
/M: SY='L';  M=  25,  24, -85, -80,   4, -81, -80,  33, -79,  33, -49, -79, -83, -77, -81, -24, -19,  23, -79, -23;
/M: SY='V';  M= -38,  26, -79, -75, -64, -82,  -7, -23, -41,  18, -22, -72, -81, -72,  -7,   8,  31,  52, -15, -67;
/M: SY='A';  M=  70,  13, -74, -71, -44,  33, -76, -23, -40, -75, -70, -66, -75, -68, -34,  -6, -62, -64, -82, -77;
/M: SY='R';  M= -47, -28, -68,   0, -76, -46, -65, -69,  33, -15, -65, -65, -33,   2,  72, -66, -20,   6, -82, -28;
/M: SY='K';  M= -26, -84, -65, -30, -84, -77, -13, -46,  83, -81, -71, -59, -26, -14,  32, -39, -15, -46, -82, -72;
/M: SY='P';  M=   8, -28, -15, -25, -84, -10, -72, -32,  15, -28, -73,  19,  26, -27,   2,  14, -37, -39, -90, -80;
/M: SY='P';  M= -23, -18, -14,   1, -51,  -7, -26, -29, -21, -41, -16, -78,   8, -15,   0,  -5, -78, -30, -96, -32;
/M: SY='R';  M=  -6,-110, -19,  -2,-109, -71, -96, -41, -55, -77, -32, -92, -52, -25,  16, -27, -36, -67,-115,-102;
/I:         E1=0; IE=-380; DE=-380;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2019_09 which contains 561'176 sequence entries.


Total number of hits 13 in 13 different sequences
Number of true positive hits 13 in 13 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] SAM-dependent MTase NNMT/PNMT/TEMT-type
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
13 sequences

INMT_HUMAN  (O95050    ), INMT_MOUSE  (P40936    ), INMT_PONAB  (Q5RFR7    ), 
INMT_RABIT  (O97972    ), NNMT1_CAEEL (P34254    ), NNMT_HUMAN  (P40261    ), 
NNMT_MOUSE  (O55239    ), NNMT_PIG    (Q06AV1    ), PNMT_BOVIN  (P10938    ), 
PNMT_HUMAN  (P11086    ), PNMT_MOUSE  (P40935    ), PNMT_PIG    (Q06AU9    ), 
PNMT_RAT    (P10937    )
» more

PDB
[Detailed view]
50 PDB

1HNN; 1N7I; 1N7J; 1YZ3; 2A14; 2AN3; 2AN4; 2AN5; 2G70; 2G71; 2G72; 2G8N; 2I62; 2IIP; 2OBF; 2ONY; 2ONZ; 2OPB; 3HCA; 3HCB; 3HCC; 3HCD; 3HCE; 3HCF; 3KPJ; 3KPU; 3KPV; 3KPW; 3KPY; 3KQM; 3KQO; 3KQP; 3KQQ; 3KQS; 3KQT; 3KQV; 3KQW; 3KQY; 3KR0; 3KR1; 3KR2; 3ROD; 4DM3; 4MIK; 4MQ4; 5XVK; 5YJF; 5YJI; 6B1A; 6CHH
» more

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission