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Entry: PS51684

General information about the entry

Entry name [info] SAM_MT_TRM5_TYW2
Accession [info] PS51684
Entry type [info] MATRIX
Date [info] 01-AUG-2013 CREATED;
10-MAY-2017 DATA UPDATE;
13-NOV-2019 INFO UPDATE.
PROSITE Doc. [info] PDOC51555
Associated ProRule [info] PRU01021

Name and characterization of the entry

Description [info] SAM-dependent methyltransferase TRM5/TYW2-type domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=264;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=259;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6157651; R2=0.0083825; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=17352.2695312; R2=17.3606586; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=2074; H_SCORE=53358; N_SCORE=20.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=464; H_SCORE=25408; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-33; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='F';  M= -73, -75, -84, -79, 101, -80, -63, -52, -74, -16, -52, -76, -83, -78, -73, -71,  -3, -57,  90,  65;
/M: SY='E';  M= -39, -74,  44,  75, -79, -67, -56, -72, -48, -73, -69, -49, -60,  31, -56,  33,  35, -20, -84, -69;
/M: SY='T';  M= -60, -72, -67, -60, -62, -76, -64,  49,   5, -14,  49, -58, -68,  45,  31, -54,  60, -15, -77, -60;
/M: SY='V';  M=  -3, -71, -77, -74,   5, -80,  49,  62, -72, -16, -42, -70, -75, -71, -74, -64,  -1,  64, -79, -54;
/M: SY='G';  M= -10, -76, -65, -74, -83,  99, -71, -88, -69, -85, -74, -52,   7, -67, -76, -49, -67, -81, -74, -78;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='H';  M= -66, -77,  52, -49, -70, -66, 123, -78, -20, -22, -59,  40, -70, -50, -55, -20, -25, -78, -98, -48;
/M: SY='I';  M= -62, -73, -85, -81, -48, -88, -82,  87, -78,  31, -35, -78, -77, -75, -80, -73, -58,  44, -76, -57;
/M: SY='A';  M=  73, -65, -71, -66, -64, -32, -72,  22, -66,   4, -51, -65, -69, -63, -70,  -3,   1,  20, -77, -66;
/M: SY='H';  M= -68, -79, -60, -59, -61, -75, 135,  28, -63,  -3, -47, -50, -72, -53, -58, -62, -65, -20, -94, -41;
/M: SY='L';  M= -64,   7, -84, -77,   7, -85, -70,  22, -77,  71,  24, -80, -82, -72, -75, -74, -61,  29, -69,   3;
/M: SY='N';  M=   9, -69, -42, -20, -78, -53, -49, -75,  -9, -80, -68, 106,  22,  -1, -56,  14, -48, -74, -88, -72;
/M: SY='L';  M= -65, -72, -78, -13,  11, -85, -71,  46,   6,  68, -35, -76, -78, -67, -68, -73, -61,   4, -70, -53;
/M: SY='R';  M= -29,   7,  15,  -8, -77, -66,  -8, -76,  26, -47, -66,  37,  50, -49,  63,  13, -10, -73, -82, -68;
/M: SY='E';  M= -30,  47,  66,  68, -78, -28, -57, -76, -52, -13, -69,  23,   0, -48, -61,  -3, -57, -72, -87, -71;
/M: SY='E';  M=  -8, -79, -44,  83,  18, -71,  34, -74, -47, -70, -66, -24,  34,  13,   5, -12, -59, -39, -76, -61;
/M: SY='Q';  M= -65, -79, -66, -11, -10, -77,  55,  37, -14,  17, -47, -63, -74,  60,   8, -35, -62, -19,  41,  48;
/I:         I=-25; MD=-63;
/M: SY='L';  M= -20, -77,  27, -22, -59, -77, -68, -30,  10,  53,  41, -68,   5, -64, -67,  -1, -63, -56,  30, -62; D=-25;
/I:         I=-25; MI=0; MD=-63; IM=0; DM=-63;
/M: SY='P';  M= -72, -94, -13,  22, -31, -34, -74, -86, -13, -91, -81, -15,  94, -67, -75,  -1, -67, -87, -89, -85; D=-25;
/I:         I=-25; DM=-63;
/M: SY='Y';  M= -74, -85, -77, -77,  49, -81, -58,   0,  -7, -61, -61,  -2,  -4, -71, -70,   7, -67, -65, -50,  93; D=-25;
/I:         I=-25; DM=-63;
/M: SY='K';  M= -34, -84, -33,  -8, -72, -40, -64, -24,  70, -28, -66, -62, -75, -52,  49, -66, -66, -23, -75,  20; D=-25;
/I:         I=-25; DM=-63;
/M: SY='Y';  M= -36, -85, -32, -63,  19, -20,  42, -36,  47, -71, -65, -27, -79, -57,  41, -67, -69, -74, -63,  65; D=-25;
/I:         I=-25; DM=-63;
/M: SY='L';  M= -71, -80,   6,   5,  -8, -87,  16,  18,  -3,  49, -48, -74,  -1, -69, -72, -75, -67,   7, -82, -62; D=-25;
/I:         I=-25; DM=-63;
/M: SY='I';  M= -66, -80, -12,   6, -60, -43, -79,  86, -70, -45, -47, -15, -75, -69, -12, -69,  -2,   6, -81, -64; D=-25;
/I:         I=-25; DM=-63;
/M: SY='G';  M=  38, -72, -64,  22, -68,  63, -70,  30, -66,  -5, -57, -60, -68, -62, -71, -53, -60,  -8, -75, -69;
/M: SY='W';  M=  29, -76, -58,  32, -72,   4,  -6,   1,  24, -66, -60, -57, -66,  66, -16, -53, -17, -16,  71, -61;
/M: SY='V';  M=  -5,  -8,  25,  24, -22, -31, -71,  29, -62, -38, -52, -64,  -5, -62, -11, -11, -54,  63, -82, -63;
/M: SY='I';  M= -18, -71, -77, -15, -51, -82, -75,  64, -70,  41,  -3, -73, -75, -68, -22, -66,  14,  37, -77, -58;
/M: SY='L';  M= -26,  15, -81, -75, -45, -82, -69,  43, -22,  56,  43, -76, -79, -69, -71, -71, -59,  31, -70,  20;
/M: SY='D';  M=  14, -76,  85,  30, -75, -67, -56, -70, -22, -47, -68, -47, -68, -50,  37, -28, -57,  -3, -84,  -3;
/M: SY='K';  M= -62,   3, -57,  -6, -73, -72,   6, -69,  91, -27, -61, -16, -66, -44,  29, -58, -17,  -8, -76, -64;
/M: SY='N';  M= -18, -72, -12, -14, -66, -63,  44, -59, -53,   3, -57,  81,  33, -54,  11, -14, -53,  15, -84, -14;
/M: SY='P';  M=  -1, -76, -67, -60,   4, -71, -63,   6,  39,  25, -52,  -2,  71, -60, -58, -34,  -8, -56, -68,  21;
/M: SY='N';  M= -10,  -8, -16, -58, -14,  34,  34, -70,  -1, -37, -64,  43,  36,   2,   0,  18,   2, -25, -80, -64;
/M: SY='C';  M= -11,  66, -76, -21, -56, -33, -77,  59,  -2,  12, -45, -70, -76, -69, -34, -65, -25,  47, -80, -63;
/M: SY='K';  M= -60, -76, -58, -14, -73, -72, -58, -19,  72, -25, -58, -53, -67,  61,  39, -19,   1,   1, -75, -63;
/M: SY='T';  M=  -3, -68, -60, -58, -71, -25, -65, -62,   3, -67, -61, -52,  33, -22,  23,  -3,  88, -14, -83, -67;
/M: SY='V';  M= -12, -67, -81, -75, -52, -81, -80,  11, -74,  27, -40, -76, -77, -74, -75, -64,   3,  85, -83, -60;
/M: SY='V';  M=   8,   8, -81, -77,  15, -80, -71,  54, -74,   8, -42, -75, -78, -72, -75, -66, -57,  57, -65,  50;
/M: SY='N';  M= -17, -71, -18, -58, -72,  12, -54, -35,  -7, -28,   1,  85, -71,  -6,  37, -50,  18, -10, -84, -67;
/M: SY='K';  M= -63, -77,   3, -43, -74, -68, -54, -78,  93, -77, -66,  27, -66,   6,  35, -56, -57, -75, -72,   5;
/M: SY='T';  M= -57, -72, -69, -66,   4,  31, -69,  31,  12,   5,   6, -60, -70, -21,  13, -22,  41,  19, -75, -59;
/M: SY='D';  M= -31, -73,  46,  11, -75,  39,  18, -10, -13, -45, -66,  45, -67, -53,  -6,  21,   3, -40, -84, -67;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='T';  M= -37, -72, -54,  31,  -3, -14, -61,   1,  20, -19, -59,  31,  18,  23, -56,   9,  42, -15, -77, -63;
/M: SY='I';  M= -59, -73,  -1, -69, -55, -78,  19,  76, -67,   4, -43, -64, -72, -66, -11,  19,   9,  26, -79, -58;
/M: SY='H';  M= -14, -75,  44,  25, -79, -25,  46, -76,  19, -76, -67,   1,  24,  36, -53,  31,  23, -72, -84, -65;
/M: SY='N';  M= -31, -70,   0, -57, -77,  33, -53, -74, -54, -77,   6,  88,  -1,  12, -61,  28,  19, -72, -86, -70;
/M: SY='D';  M= -27, -76,  51,  41, -73,   2, -61, -57,  -1,  -9, -60, -54, -11,  51, -57, -56,  -4,  31, -82, -67;
/M: SY='Y';  M= -70, -74, -72, -74,  86, -77,   8, -17, -69, -49, -51,   5, -80, -70, -68, -64,  13, -56, -40,  96;
/M: SY='R';  M= -65, -82, -59,  10, -76, -76, -53, -81, -27, -74, -64, -55, -72,  16, 108, -58,  -2, -75, -76, -63;
/I:         I=-12; MD=-30;
/M: SY='T';  M= -62, -71,  -9, -26,   4, -74, -69, -11, -65, -20, -62,  34, -71, -67, -72, -18,  82, -10, -85, -16; D=-12;
/I:         I=-12; MD=-30;
/M: SY='F';  M= -77, -84, -85, -78,  82, -84, -70, -64, -70, -32,  10, -79,  42, -76,  22, -21, -72, -68,  54,  26; D=-12;
/I:         I=-12; MD=-30;
/M: SY='E';  M= -22, -89,  29,  56, -92, -76,  16, -89,  16, -87, -79,  14,  41,  20, -61, -64, -67, -86, -92, -79; D=-12;
/I:         I=-12; MI=0; MD=-30; IM=0; DM=-30;
/M: SY='M';  M= -76, -83, -93, -86,  28, -40, -76,  -5, -84,  39,  82, -85,   4, -80, -84, -81, -15, -55, -79, -60; D=-12;
/I:         I=-12; DM=-30;
/M: SY='E';  M= -65, -85,   0,  88, -82, -33, -65, -30, -55, -32, -72, -65, -68, -49, -64,  -8, -65,   3, -88, -77; D=-12;
/I:         I=-12; DM=-30;
/M: SY='L';  M= -66, -76, -75,   1, -59, -86,  30,  -8, -16,  47, -46, -75, -81,  10, -70, -71,  -8,  45, -84, -63; D=-12;
/I:         I=-12; DM=-30;
/M: SY='L';  M= -70, -76, -80,   7, -49, -90, -75,  55, -77,  69, -36, -82, -82, -71, -78, -78, -65, -38, -76, -59; D=-12;
/I:         I=-12; DM=-30;
/M: SY='A';  M=  70,  37, -74, -66, -69,  -3, -73, -64, -27,  18, -58, -68, -75,  11, -70, -54, -61, -58,  46, -68; D=-12;
/I:         I=-12; DM=-30;
/M: SY='G';  M= -57, -79, -71, -80, -67,  87, -70, -72, -74,   6, -65, -60, -75, -71, -79, -58, -70, -24, -71,  29; D=-12;
/I:         I=-12; DM=-30;
/M: SY='E';  M= -62, -81,  22,  71, -82,  28,   2, -36, -28, -77, -72,  30, -67,  -2, -17, -58, -63,  -8, -86, -74; D=-12;
/I:         I=-12; DM=-30;
/M: SY='N';  M= -35, -75,  38,  -1, -79, -36, -54, -75,  25, -78,   6,  71,  62, -51,  -5,  15, -53, -75, -85, -71;
/M: SY='D';  M= -14, -74,  70,   8, -75, -36,  21, -29, -50, -27, -66,  59, -69, -51,  27,  16, -54, -29, -89, -66;
/M: SY='Y';  M= -63, -72, -33, -71,  33,   1, -58,  12, -67,  19,  27, -64, -74, -66, -69, -58,  56, -49, -54,  78;
/M: SY='W';  M= -63, -78,  10,  51, -57, -76,  19,  10, -59,  10, -54,   3, -71, -56, -18, -64, -28,  32, 106, -53;
/M: SY='T';  M=  28,  30, -32, -67, -61, -70, -74, -40, -66,  -7, -51, -61, -70, -68, -71, -49,  71,  60, -85, -65;
/M: SY='E';  M= -57, -72, -54,  51, -66, -72, -64,  43,  29, -17, -54,  -7, -64, -13, -56,  15,  43,  -3, -79, -64;
/M: SY='H';  M= -25,  29, -69, -65, -57, -77,  98,  -2, -67,  21, -45, -62, -76,  14, -65, -63, -59,  58, -87, -52;
/M: SY='K';  M= -61, -76, -63, -56, -67, -27,  53,  19,  57, -61, -56, -18, -12, -51,  47, -11, -17,  27,  15, -59;
/M: SY='E';  M= -60,  -4,   4,  98, -85, -73, -52, -82, -42, -75, -69, -54, -59,  69, -49, -55, -61, -77, -79, -70;
/M: SY='N';  M= -57, -70,  -4, -16, -68,  -4,  37, -75, -53, -77, -67,  94, -70, -18, -58,  45, -14, -74, -81,  28;
/M: SY='G';  M= -52, -77,  35, -30, -83,  93, -66, -89, -36, -85, -76,   9, -68, -63, -71, -50, -65, -83, -78, -76;
/M: SY='C';  M= -23, 101, -81, -79, -21, -81, -75,  58, -75,  -8,  -9, -72, -80, -75, -78, -66, -30,  35, -74,  32;
/M: SY='R';  M= -61,  17, -64, -31, -62, -74, -60,   8,  37,   6, -54, -57, -70,  -4,  61,  -1,  38, -22, -73,  13;
/M: SY='F';  M= -29, -74, -78, -71,  89, -79, -57,  -7, -69,  11, -47, -72, -81,  36, -67, -68, -64, -22, -45,  73;
/M: SY='K';  M= -60,   7, -57,   8, -17, -70, -59,  -9,  67, -68, -20,  -6, -67,  31,  36,   6,  11, -34,  34, -61;
/M: SY='W';  M= -68, -72, -87, -79,  81, -83, -73, -12, -77,  44,  23, -80, -82, -77, -75, -74, -64,  29,  82, -35;
/I:         I=-8; MD=-21;
/M: SY='D';  M= -15, -77,  99, -40, -84, -61, -54, -78, -56, -82, -77,  55, -16, -55, -64,  -4, -55, -29, -99, -72; D=-8;
/I:         I=-8; MD=-21;
/M: SY='F';  M= -25, -75, -81, -76,  76, -80, -64,   5, -74,   2, -49, -77,  32, -75, -74, -70, -63,  28, -51,  67; D=-8;
/I:         I=-8; MD=-21;
/M: SY='S';  M=  49, -67, -19,  11, -13, -35, -65, -63, -58, -21, -62, -56, -67, -56,  -2,  49,  33, -10, -79, -66; D=-8;
/I:         I=-8; MD=-21;
/M: SY='K';  M= -63, -77, -14,  -9,   2, -71, -57, -69,  77, -24, -62,  10, -69,  22,  15,  -7, -31, -26, -70,  14; D=-8;
/I:         I=-8; MD=-21;
/M: SY='V';  M= -56,  57, -81, -78, -57, -84, -84,  34, -75, -44, -46, -74, -78, -77, -78, -64,  24,  84, -88, -64; D=-8;
/I:         I=-8; MD=-21;
/M: SY='Y';  M= -70, -78, -76, -75,  10, -79, -44, -50, -68, -21,  90, -73, -81, -62, -65, -69, -65, -56, -39, 115; D=-8;
/I:         I=-8; MD=-21;
/M: SY='W';  M= -76, -88, -97, -82,  76, -78, -85, -63, -75, -57,   7, -88, -83, -78, -76, -80, -80, -72, 156,   0; D=-8;
/I:         I=-8; MD=-21;
/M: SY='N';  M= -54,  51, -46, -60, -77, -53, -52, -77, -54, -81, -71,  98, -72, -53, -61,  66, -45, -74, -92, -72; D=-8;
/I:         I=-8; MD=-21;
/M: SY='S';  M= -53, -74, -62, -58,  16, -61, -62, -73, -55, -74, -68, -55,  65,   4,  23,  77,   2, -69, -77, -63; D=-8;
/I:         I=-8; MD=-21;
/M: SY='R';  M= -21, -83, -66, -58, -80,  41, -60, -86,   6, -80, -69, -57, -75, -49,  96, -60, -68, -79, -78, -69; D=-8;
/I:         I=-8; MD=-21;
/M: SY='L';  M= -68, -71, -67, -73, -51, -75, -62, -44, -69,  72,  22,  68, -83, -66, -71, -68, -60, -50, -80, -60; D=-8;
/I:         I=-8; MD=-21;
/M: SY='S';  M= -16, -76, -62,   0, -69, -25,  39,  26,   7, -64, -60, -56, -70,  38, -10,  55, -54,   1, -79,  -5; D=-8;
/I:         I=-8; MD=-21;
/M: SY='H';  M= -34, -74, -59,   6, -70,   8,  62, -10,  33, -70, -63, -52, -67, -19, -56,  16,  59, -64, -81,   5; D=-8;
/I:         I=-8; MD=-21;
/M: SY='E';  M= -63, -84, -34, 109, -86, -79, -56, -87, -44, -79, -76, -59, -58, -36, -54, -59, -63, -80, -83, -76; D=-8;
/I:         I=-8; MD=-21;
/M: SY='H';  M= -70, -84, -60, -53, -76, -76, 110, -86,  42, -75, -62, -51, -73, -46,  73, -62, -68, -82, -87, -53; D=-8;
/I:         I=-8; MD=-21;
/M: SY='M';  M=  24, -75,  24,  20, -65, -41, -62, -28,  14,  12,  44, -26, -71,  25, -30, -59, -15, -17, -76,   8; D=-8;
/I:         I=-8; MD=-21;
/M: SY='R';  M= -68, -84, -65, -26, -77, -78, -56, -30,  -8, -47, -65, -59, -77, -44, 106,  -6, -65, -74, -79, -65; D=-8;
/I:         I=-8; MD=-21;
/M: SY='M';  M= -64, -73, -87, -81, -51, -88, -78,  55, -78,  42,  58, -81, -81, -75, -79, -75, -60,  52, -79, -59; D=-8;
/I:         I=-8; MD=-21;
/M: SY='A';  M=  39, -71, -77, -72, -15, -23, -72,  32, -69,  17,  10, -69, -75, -68, -18,   2,  -4,  25, -75,  -5; D=-8;
/I:         I=-8; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='F';  M= -36, -74,  33, -12,  41,  13, -58, -39,  35, -35, -64,  22, -29,  34,  -1,  28, -56, -68, -72, -56;
/M: SY='M';  M= -60, -11, -34, -63,  12, -74, -64,  -9,  24,  38,  61, -63,   7,   2, -60,   8,  30,  -5, -73, -55;
/M: SY='F';  M=   7,  -4,  20, -64,  62, -70, -63,   8, -36,  -3,  23,   2, -75,  -5, -67,   9, -56,  20, -64,  16;
/M: SY='C';  M= -61,  62, -10,  11, -73, -28, -58,  15,  44, -67,   7,  55,  -2,  36, -21, -17, -13, -63, -82, -68;
/M: SY='P';  M=   6,  29,  -2,  25, -78, -66, -11, -73,  42, -36, -66, -10,  71, -51,   3,  10, -17, -70, -80, -71;
/M: SY='N';  M= -37, -75,  49,  -2, -82,  65,  -9, -84, -56, -83, -73,  71, -68,  18, -63, -49, -58, -81, -84, -72;
/M: SY='E';  M= -59,  19,  65,  77, -81, -67, -55, -29, -48, -76, -72,   9, -62,  15, -57,  20, -29, -73, -86, -71;
/M: SY='V';  M= -15, -70,  -2, -70, -53, -80, -74,  46, -24,  26,  21, -71, -76, -68,  -8, -66, -27,  64, -80, -59;
/M: SY='V';  M= -58, -69, -84, -78, -49, -86, -81,  46, -76,  36, -37, -79, -79, -75, -77, -70, -55,  80, -80, -58;
/M: SY='C';  M=  31,  80, -78, -74,  12, -37, -72, -39, -72,   7, -49, -72, -79, -73, -74, -61, -56,  61, -72,  31;
/M: SY='D';  M= -67, -80, 117, -32, -86, -65, -54, -80, -56, -81, -81, -36, -67, -55, -64, -56, -57, -21,-103, -70;
/M: SY='M';  M=  18, -69, -79, -70, -54, -25, -67, -37, -70,  40,  90, -73,  33, -66, -71, -64, -58,  38, -76, -59;
/M: SY='F';  M= -71,   6, -82, -79, 100, -80, -58, -48, -73, -41,  72, -73, -81, -75, -71, -70, -14, -53, -44,  64;
/M: SY='A';  M=  88,  83, -70, -63, -75, -28, -71, -68, -65, -68, -63, -63, -70, -63, -70, -26, -54, -55, -79, -73;
/M: SY='G';  M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78;
/M: SY='V';  M=  -5, -70, -83, -78, -53, -83, -85,  73, -75, -37, -40, -76, -76, -75, -78, -67, -54,  77, -81, -60;
/M: SY='G';  M= -50, -77, -65, -76, -81, 101, -72, -18, -70, -82, -72, -51, -68, -68, -77, -50, -68, -78, -74, -77;
/M: SY='P';  M= -30, -87, -67, -59, -58, -70,  18, -25, -64, -72, -62, -71, 111, -64, -71, -63, -60, -70, -61,  71;
/M: SY='F';  M= -73, -72, -85, -81, 113, -83,  12, -27, -77,  -2, -48, -75, -85, -83, -74, -73, -66, -22, -44,  19;
/M: SY='A';  M=  65,  10, -64, -61, -72, -56, -68, -61, -61, -66, -62, -56,   2, -59, -67,  45,  52,  -1, -81, -69;
/M: SY='I';  M= -65, -72, -85, -80,  31, -87, -76,  69, -78,  52,   1, -79, -79, -75, -78, -74, -60,  28, -69, -50;
/M: SY='P';  M= -26, -81, -67, -59, -67, -68,   5, -63, -58,  -3, -60, -66, 101, -60,  16,  22, -56, -17, -73,  22;
/I:         I=-36; MD=-90;
/M: SY='A';  M=  69, -68, -75, -69,  21, -64, -67,  22, -69,  17, -50, -70, -74, -66, -71, -32, -58, -28, -64,  40; D=-36;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='A';  M=  71,  13, -69, -64, -66, -11, -69, -56, -65,  18, -54, -62, -12, -61, -69,  24,  -2,  -8, -77, -67;
/M: SY='K';  M= -35, -74, -61, -49, -70, -72, -61, -58,  86, -12, -57, -54, -67,  12,  20, -32,   0,  25, -75, -64;
/M: SY='K';  M=   6, -75, -14, -49,  -2, -67,  21, -36,  77, -70, -62,  19, -68,  -1,  31, -55, -31, -68, -68,  31;
/M: SY='G';  M=  21, -72, -61, -63, -12,  68, -64, -73,  21, -25, -65,  26, -69, -57,  14,  -1, -59, -43, -74, -67;
/M: SY='C';  M=  15, 100, -61, -23, -71, -17, -65, -36,  43, -46, -62,  45, -74, -59, -57, -31, -24,  11, -85, -71;
/I:         I=-28; MI=0; MD=-70; IM=0; DM=-70;
/M: SY='T';  M= -62, -72, -62,  -9,  37, -48, -61, -28,  35,  16, -54,  16, -70,  -6,  21, -18,  44, -35,  44, -11;
/M: SY='V';  M= -55,  46, -82, -77, -52, -83, -80,  11, -74,   3, -43, -76, -79, -76, -76, -66, -18,  89, -82,  -2;
/M: SY='Y';  M= -69, -77, -77, -74,  53, -80,  43,  19, -69,  21,  25, -72, -80, -66, -32, -70, -65, -22,  51,  89;
/M: SY='A';  M=  90,  51, -67, -61, -75, -27, -69, -67, -19, -68, -63, -61, -68, -59, -66,   3, -52, -55, -78, -72;
/M: SY='N';  M= -63,  59, -49, -64,   3, -60, -54,  20, -55, -66, -62, 102, -76, -58, -15, -27, -52, -15,  52, -62;
/M: SY='D';  M= -65, -81, 102,  64, -86, -67, -53, -85, -50, -82, -80,  -1, -63, -47, -59, -55, -58, -81, -95, -71;
/M: SY='W';  M= -28, -74, -82, -73, -45, -82, -73,  41,   7,  70, -36, -78, -79, -68, -69, -73, -63, -40,  85, -51;
/M: SY='N';  M= -63, -68,   3, -55, -77, -51, -43, -77, -13, -84, -70, 122, -73, -50, -55, -45, -47, -79, -95, -72;
/M: SY='P';  M= -65, -89, -65,  -7, -81, -69, -69, -23, -62, -40, -67, -72, 121, -64, -74, -23, -58, -73, -79, -80;
/M: SY='W';  M= -38, -79,  32,  38,  -1, -71,  71,  -9, -19, -65, -62,  -7, -69, -52,  -3, -12,   5, -31,  91,  29;
/M: SY='S';  M=  63,  10, -61, -59, -75,  -8, -64, -70, -18, -72, -66, -52, -65, -54, -63,  74,  -3, -60, -79, -69;
/M: SY='Y';  M=  -9, -72, -77, -75,  14, -79,  -9,  23, -71, -18, -45, -74, -79, -69, -70, -65, -58,  64, -53,  89;
/M: SY='E';  M= -60, -76, -46,  68, -71, -71,  31, -73,  68, -72, -65,  -9, -62, -41, -19, -22,   7, -19, -75,  11;
/M: SY='Y';  M=  32,   8, -73, -71,  19,   5, -57, -59, -67,  -6, -55, -67, -76, -64, -68,  11, -60, -37,  83,  88;
/M: SY='L';  M= -19, -69, -84, -75, -43, -82, -66, -33, -75,  83,  67, -80, -81, -68, -73, -74, -62, -40, -72, -53;
/M: SY='K';  M= -43,  19, -55,  36, -72, -73, -58, -62,  54, -22, -59,   4, -68,  36,  50, -57, -26,  20, -78, -65;
/M: SY='E';  M= -61, -77, -24,  59, -71, -29,  27,  17,  33, -63,  10,   2, -65, -45,  45, -34, -10,  -7, -79, -64;
/M: SY='N';  M=  -4, -67, -39, -58, -76,  -7, -46, -72, -50, -80, -68, 116, -72, -52, -59, -15, -48, -28, -92, -72;
/M: SY='I';  M=  37,  38, -79, -74,  -8, -74, -77,  67, -71,  17, -43, -72, -75, -70, -31, -36, -56,  27, -75, -59;
/M: SY='K';  M= -39, -76, -53,  39, -71, -11,  39, -25,  67, -10,  12,   7, -66, -14,  21, -58, -59, -20, -77, -62;
/M: SY='L';  M= -14, -72, -12, -23, -22, -79, -67,  44,  -7,  57,  13,  -8, -76, -63,   8, -67, -26, -15, -74, -57;
/M: SY='N';  M= -62, -68,  -2, -56, -77, -50, -43, -76, -48, -84, -70, 124, -73, -50, -57, -44, -47, -79, -97, -72;
/M: SY='K';  M= -61, -78, -57, -49, -78,  36,  49, -82,  87, -78, -66, -49, -66, -44,  35, -56, -61, -78, -75, -63;
/M: SY='V';  M= -22,  -9,  -7, -70,   6, -80, -76,   5, -37,  21, -45, -72, -78, -70,   4, -66, -23,  73,  52, -55;
/M: SY='E';  M=   8, -73,  19,  56, -33, -62,  11, -73,   1, -45,   0,  46, -64,  13,  -3,  31, -22, -69, -81, -65;
/M: SY='D';  M= -39, -76,  56,   6, -14, -21,  10,   3,  22, -14, -62,  42,  20,  11,  -4,  -6, -56, -65, -81, -63;
/I:         I=-36; MD=-90;
/M: SY='R';  M= -26, -79,  -4,  -4,  14, -44, -60, -70,  29,   0, -62,   3, -76,  -5,  54,  -7, -14, -69, -72,  24; D=-36;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='C';  M= -34,  74, -84, -79, -14, -84, -81,  64, -76,  -2,  19, -75, -79, -76, -78, -69, -56,  61, -80, -59;
/M: SY='K';  M= -35,  -9,   5,  28, -68, -72,  42,  25,  46, -32, -56, -53, -66,   8, -20, -11,  37,   4, -81, -62;
/I:         I=-26; MD=-67;
/M: SY='P';  M=  -3,  55, -76, -71, -66, -77, -78,  44, -69, -55, -54, -23,  64, -72, -22, -63,   7,  45, -85, -70; D=-26;
/I:         I=-26; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='F';  M= -67, -75, -73, -70,  72, -78,  60,  38, -65,  -6,  -1, -65, -77,  -8,  -2,  -1, -27, -49, -54,  57;
/M: SY='N';  M= -63,  38, -15,   1,  -4, -33,  22, -69, -15,  -1, -61, 101, -73,  13, -57, -51, -53, -71, -86, -63;
/M: SY='M';  M=  -6, -72, -67,  18, -60,  46, -62, -25,  -7,  25,  94, -62, -69, -58, -64, -19, -61, -54, -74, -61;
/M: SY='D';  M= -64, -79, 111,   4, -86, -63, -53, -85, -53, -83, -81,   0, -66, -52, -25,  10, -55, -81, -99, -70;
/M: SY='N';  M=  40, -69, -21, -63, -75,  55, -61, -65, -19, -72, -65,  69, -70, -59, -65, -18, -54,  14, -81, -72;
/M: SY='R';  M= -17, -78, -62,  -3,  12, -73, -53, -23,   0, -66, -60, -11, -74, -47,  91,  -5, -61, -30, -65,  40;
/I:         I=-11; MD=-28;
/M: SY='E';  M= -35, -93,  46,  55, -92, -85, -71, -87, -36, -39,  39, -12, -80, -62, -37, -22, -74, -85,-101, -84; D=-11;
/I:         I=-11; MI=0; MD=-28; IM=0; DM=-28;
/M: SY='E';  M= -66, -76,  13,  49,  48, -78, -59, -14,  21,  16,  14, -61, -70, -51,  48, -64, -62, -33, -69, -52;
/M: SY='I';  M= -63, -71, -77, -73,  25, -81, -70,  46, -65,  40,  25,   2, -78, -68,  21, -68, -11,  40, -72, -52;
/M: SY='K';  M=   5, -72,  19,   8, -71, -14, -10, -33,  48, -10, -59, -12,  -1,   7,  -9, -18,  29,   4, -80, -66;
/M: SY='V';  M= -60, -74,  -7,  26, -61, -22, -66,   7,  -1,  22,  21, -64,  24, -22,  20, -31, -20,  40, -79, -63;
/M: SY='W';  M= -61, -75, -59,  30,  34, -71, -62, -18,  46,   3, -10,  18,   4,  -5, -52,   8, -57,   7,  58, -53;
/I:         I=-4; MD=-9;
/M: SY='L';  M= -40, -75, -70, -68, -59, -24, -66,  -4,   2,  45,   7,  30, -78,  22, -66, -19,  14, -10, -78,  -2; D=-4;
/I:         I=-4; MD=-9;
/M: SY='P';  M=  -1, -11,  12,  27, -29, -17,   6,  32, -19, -67, -64, -63,  35, -59,  -4,  10, -62, -60, -76,  26; D=-4;
/I:         I=-4; MD=-9;
/M: SY='N';  M= -42, -85,   9,  15, -89,   2, -64, -87,  30, -43, -77,  50, -77,  28,  -8,   2, -65, -85, -92, -79; D=-4;
/I:         I=-4; MD=-9;
/M: SY='K';  M= -42, -88,  34, -60, -32, -77,  -5, -87,  46, -86,   4,  43,  -7, -62,   5, -33, -15, -85, -95, -77; D=-4;
/I:         I=-4; MD=-9;
/M: SY='V';  M=  13, -85, -80, -26, -10, -46, -82,  23, -12, -36, -65,   4,  16, -75, -10, -72, -69,  29, -90, -75; D=-4;
/I:         I=-4; MD=-9;
/M: SY='G';  M= -76, -93, -84,  -9, -18,  22, -81, -27, -40,  11, -69, -81, -28,  12, -83, -10, -78, -13, -85,  11; D=-4;
/I:         I=-4; MD=-9;
/M: SY='Q';  M=  -5,-101,   4, -78,  -2, -93, -88, -42, -25, -93, -89, -81, -96,  34,  -7,  -8,  -7, -52,-102, -86; D=-4;
/I:         I=-4; MI=0; MD=-9; IM=0; DM=-9;
/M: SY='C';  M= -90,   0, -94, -44, -20,-102, -89, -12,  -3, -14,  -2, -38, -17, -15, -12, -28, -22, -48, -98, -10; D=-4;
/I:         I=-4; DM=-9;
/M: SY='G';  M= -81, -98, -23, -89, -11,  27,   8, -91, -84,  -7, -83, -79, -97, -84,   3,  11, -24, -91,-100, -84; D=-4;
/I:         I=-4; DM=-9;
/M: SY='F';  M=  43,  -8, -18, -23,  46, -25, -65,  31, -19, -25, -54, -15,  19, -23,   3, -31, -58, -28, -66,   6;
/M: SY='D';  M= -61, -75,  81, -46, -74, -67,  -2,   4, -13, -68, -65,  26, -69, -54,  32,  10,   2,  15, -90, -65;
/M: SY='H';  M= -26, -81, -57, -53, -67, -72, 129, -82, -46, -69, -56, -48, -72,   2,  62, -58, -66, -80, -86,  10;
/M: SY='V';  M= -60, -70, -84, -80,  51, -85, -78,  55, -76,  -3, -41, -78, -79, -78, -77, -70, -56,  72, -68,   3;
/M: SY='I';  M= -60,  17, -74, -76, -10, -80, -73,  63, -71,  10, -42,  30, -77, -71, -75, -64,   1,  57, -77,  -4;
/M: SY='M';  M= -62, -69, -82, -73,  -4, -76, -58, -17, -68,  33, 130, -71, -73, -61, -67, -14, -59, -42, -72, -49;
/M: SY='N';  M= -58, -70, -43, -61, -79,  49, -50, -79, -54, -84, -71, 107,   1, -54, -62, -11, -51, -79, -88, -74;
/M: SY='L';  M= -66, -70, -81, -75, -39, -84, -63, -35, -75,  82,  29, -79, -82, -68, -72, -73,  -7, -42, -64,  44;
/M: SY='P';  M= -65, -85, -71, -60, -71, -72, -71, -10, -66,  12, -57, -75, 114, -68, -76, -66, -59,   3, -78, -74;
/M: SY='P';  M=  41, -74,  23,   6, -77, -36,  17, -65,  37, -70, -63, -25,  56,  10, -54, -26, -56,  10, -80, -69;
/M: SY='S';  M= -54, -70, -31, -20, -10, -16,   6,  17,   8, -11,  37, -54, -68, -54,  -7,  62,  26, -54, -72,  17;
/M: SY='A';  M=  77, -62, -64, -60, -73, -51, -66, -63, -61, -68, -62, -55, -65, -56, -66,  58,  17, -13, -79, -69;
/M: SY='H';  M= -41, -76,  -4,  29, -13, -79,  65,  56,  -6,  12, -47, -62,   4, -59, -64, -64, -16,  15, -79, -55;
/M: SY='E';  M= -17,  17,  -8,  78, -80, -68, -55, -78,  35, -75, -68,  29, -61,  35, -48, -17,  12, -72, -81, -70;
/M: SY='F';  M= -67, -71, -79, -78, 106,   7,   3, -52, -74,  -1, -52, -69, -81, -78, -73,  10, -63, -56, -48,   7;
/M: SY='W';  M= -67, -74, -86, -77, -42, -81, -74,  11, -76,  77, -36, -82, -81, -70, -75, -16, -65, -44, 106, -48;
/M: SY='D';  M= -61, -80,  83, -15, -79,  19, -60, -75, -32, -29, -71, -48,  57,   0, -19,   4, -58, -33,   6, -70;
/M: SY='A';  M=  45,  -1, -63, -27, -65, -63,  28,   6,  22, -18, -55,  -7, -68, -56, -17,  14,  33,  11, -79, -21;
/M: SY='F';  M=  47, -68, -79, -73,  85, -70, -68,   6, -72,  16,  13, -71, -77, -72, -72, -60,  -9, -47, -56,  -5;
/M: SY='R';  M= -60,  23, -68, -61,  -5, -42, -65,  17,  18,  -7, -54, -61,  25, -56,  58,  13,  13,  20, -76, -61;
/M: SY='G';  M= -25, -75,  15,  23, -76,  55, -61, -25,  25, -74,   6, -20, -66,   8,  -9,  34, -57, -71,  30, -67;
/M: SY='W';  M=  25,  27, -77, -71,  16, -42, -73,  39, -22,  35, -45, -12, -17, -25, -71, -64, -60,  14,  69, -53;
/M: SY='Y';  M= -10, -75, -69,   6,  30, -77,  35,  17, -36,  38, -45, -70,  28, -63, -67, -65, -18, -18, -59,  61;
/I:         I=-9; MD=-22;
/M: SY='K';  M= -42, -81,  17, -56, -31, -38,  -7, -74,  43, -46, -68, -13, -74,  10,  42,   3,  18, -30,  25,  13; D=-9;
/I:         I=-9; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='S';  M= -16, -86, -18,  19, -20,  -1, -73, -82,   2, -13, -75, -27, -25, -63,  13,  30, -33, -79,   8, -75; D=-9;
/I:         I=-9; DM=-22;
/M: SY='Q';  M= -66, -87,  25,  52, -91, -16, -60, -86, -50, -82, -73, -18, -22,  80,   4, -19,  -5, -83, -86, -74; D=-9;
/I:         I=-9; DM=-22;
/M: SY='G';  M= -58, -80,  53,  10, -84,  61,  -4, -86, -59, -85, -76,  -5,  39, -58, -12,  17, -60, -82, -84, -75; D=-9;
/I:         I=-9; DM=-22;
/M: SY='H';  M=  22,  20, -69, -35,  -4,   9,  37,  29,   6,   3,  33, -12, -73, -16,  -9, -58,   8, -52, -77, -60; D=-9;
/I:         I=-9; DM=-22;
/M: SY='L';  M= -46,   5, -85,  -6, -77,  -4, -83, -35, -42,  15, -70, -83,  -8, -30,  -6,   0, -77, -12, -92,  -3; D=-9;
/I:         I=-9; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='P';  M= -70,  13, -80, -73, -16,   2, -82, -69, -76, -37, -72, -79,  91, -78, -85, -10, -68,  11,  27, -78; D=-9;
/I:         I=-9; DM=-22;
/M: SY='M';  M= -64, -71, -78, -75,  51, -80, -14,  46, -69,  21,  75, -16, -76, -69, -20, -67,   9,  16, -66,   0;
/M: SY='I';  M= -61, -72, -85, -80, -12, -87, -79,  75, -77,  27,  28, -78, -77, -74, -78, -72, -57,  56, -76, -55;
/M: SY='H';  M= -69, -81, -53, -13, -64, -71, 143, -43, -58, -67, -54, -14, -70, -48, -53, -59, -67, -81, -93,  15;
/M: SY='C';  M= -60, 109, -80, -79, -20, -81, -70,  29, -74, -49, -51, -73, -83, -76, -76, -66, -58,  55, -69,  63;
/M: SY='Y';  M= -71, -81, -64, -65,   3, -75, 107, -65, -63, -58, -51, -59, -78, -56, -59, -63, -66, -69, -44, 112;
/M: SY='C';  M= -58, 105,  -3,  32,  16,  21, -66, -72, -61, -36, -65,   0, -72,   5, -68, -29,  37, -66, -82, -66;
/M: SY='F';  M= -70, -70, -69, -74, 105, -74, -62, -17, -66, -48, -54,  54, -80, -74, -15, -62,  14, -56, -51, -30;
/M: SY='V';  M=  28,   9, -10, -28, -67,  -6,  22, -26, -64, -59, -57, -57, -69, -61, -68,  49,  14,  54, -84, -65;
/M: SY='K';  M=  -3, -78, -54,   5, -79, -13,  51, -79,  72, -77, -65,  20,  41,  -4,  23, -55, -59, -75, -78, -65;
/I:         I=-26; MD=-67;
/M: SY='S';  M=  -1, -88,  13,   7, -29, -11, -16, -12, -21, -31, -77, -69,  -9, -21, -77,  33, -69, -77,   6, -78; D=-26;
/I:         I=-26; MD=-67;
/M: SY='H';  M= -37, -95,  30, -16,  -8, -86,  32, -41,   1, -89, -84, -70,  -2, -28, -77,  21, -36, -31,-101, -79; D=-26;
/I:         I=-26; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='P';  M= -15, -94,  28,   5, -95, -49, -79, -83, -75, -88,  12,  16,  46, -74, -39, -46,  -7, -19,-104, -90; D=-26;
/I:         I=-26; DM=-67;
/M: SY='D';  M= -10, -82,  64,  42, -81, -18, -11, -82, -33, -81,  -3,  18,  18, -56, -38, -29,  -4, -78, -88,  -2; D=-26;
/I:         I=-26; DM=-67;
/M: SY='E';  M= -58, -77, -14,  66,   0,   2, -57, -19,  33, -43, -64, -54, -64,  12,  12,  29, -57, -45, -72,   1;
/M: SY='D';  M= -62, -76,  84,  33, -32, -64, -55, -18, -20, -14, -68,  46, -67, -51, -60,  21, -54, -70,  27, -65;
/I:         I=-33; MD=-84;
/M: SY='P';  M=  -5, -81, -80,  -1,  36, -82, -73,  16, -75,  21,  16, -81,  43, -73, -78, -73, -67,  -2,  40,  21; D=-33;
/I:         I=-33; MI=0; MD=-84; IM=0; DM=-84;
/M: SY='E';  M= -30,  16, -31,  40,  -3, -83, -14,  34,  -4,  14, -54, -70, -76,   5, -32, -68, -32, -22, -71,  37; D=-33;
/I:         I=-33; DM=-84;
/M: SY='E';  M=   0, -82,  12,  65, -87,  15, -60, -84,  27, -80, -72, -56, -66,  50,  -9, -56, -28, -78, -82, -74; D=-33;
/I:         I=-33; DM=-84;
/M: SY='R';  M= -63,  14,  39,  29, -68, -71, -57, -13,   1, -13, -61,  27, -69,  11,  53, -56,  19, -27,  26,  -6;
/M: SY='A';  M=  48, -70, -72, -69,  39, -17,  24,  29, -68, -52,  -9, -65,  -2, -66, -70, -15, -10,  17, -64,  41;
/M: SY='E';  M= -58,   9, -57,  46,   3, -72, -63,  30,   8, -31, -55,   1, -69,  -6,  24,  28, -54,  28, -77, -61;
/M: SY='E';  M=   3, -73, -12,  44, -76, -65, -57, -40,  33, -71, -64,  -6, -64,  34,  31,  34,  13, -12, -79, -67;
/M: SY='R';  M=  -3, -74, -13,  30, -67, -70,  13,  -3,   8,   8,   4,  19, -70,  -6,  56,  -3, -57,  -5, -79, -62;
/M: SY='V';  M= -61,   7, -81, -77,  -6, -84, -74,  46, -75,  48,  18, -75, -78, -73, -75, -68,  10,  52, -74, -11;
/M: SY='E';  M= -27, -75,  32,  52, -70,   3, -56, -26,  31,  -8, -63,  19, -65, -47,  14,   4, -10, -67, -77,  -3;
/M: SY='E';  M=   8, -73, -54,  43,  19, -20, -58, -32,  36, -33,   4,  11, -67,  28,   5,  -5, -12, -20, -70,   1;
/M: SY='W';  M= -62,  28, -58,  33, -61, -30,  24,  19,  27, -35, -58,   7, -23,  -4,  29,  -6, -30, -19,  55,  31;
/I:         I=-7; MD=-18;
/M: SY='L';  M= -53,  18, -94, -94, -77, -27,  16,  -6, -91,  30, -66,   2,-101, -89, -38, -86, -27, -13,-103, -82; D=-7;
/I:         I=-7; MI=0; MD=-18; IM=0; DM=-18;
/M: SY='C';  M=  21,  45, -75, -36,  37, -73, -71,  34, -69,  19, -47, -69, -30,   4, -71, -19,   7,  19,  29, -10;
/M: SY='E';  M= -59, -78,  45,  59, -82,  10, -56, -82,  16, -79, -72,   7,  21,   9,  22,  21, -56, -77, -82, -71;
/I:         I=-17; MD=-42;
/M: SY='R';  M= -66, -82, -66, -37, -78, -45, -66, -69,  50, -40,   3,   6,  25, -55,  51,  -8,   1,   6, -85, -72; D=-17;
/I:         I=-17; MD=-42;
/M: SY='H';  M= -21, -87, -29, -23, -23, -33,  43, -26, -69, -77,  22,  16, -26,   4,  -3,  15,   1, -26, -96, -73; D=-17;
/I:         I=-17; MD=-42;
/M: SY='G';  M= -13, -89, -82, -28, -86,  57, -83, -82, -83,  -3,  28, -73, -86, -79, -88,   2, -34, -81, -92, -85; D=-17;
/I:         I=-17; MI=0; MD=-42; IM=0; DM=-42;
/M: SY='K';  M= -86,  12, -77, -22, -97, -92,  -9,-101,  61, -98, -87,  -7, -89,  38, -57, -78, -82, -98, -95, -10; D=-17;
/I:         I=-17; DM=-42;
/M: SY='E';  M= -74,  10,   3,  18,   2, -34, -77, -65, -76,   7, -68,   3, -86, -74, -81, -13,   4,  12, -89,  -2; D=-17;
/I:         I=-17; DM=-42;
/M: SY='C';  M= -42,  43, -16,  30, -85, -82, -74, -18, -68, -77,  -1,  20,  33,  23, -75, -67,  16,  -4, -97, -82; D=-17;
/I:         I=-17; DM=-42;
/M: SY='E';  M= -69, -83,  28,  37, -73, -84, -71,   5, -28,  -5, -62,  -2, -78, -61,  27, -68, -14,  32, -91, -73; D=-17;
/I:         I=-17; DM=-42;
/M: SY='Y';  M= -66,  28, -74,  14,   9, -83, -64,  -2, -27,  30,  37, -75, -80, -66, -70,  -9, -63,  20, -65,  59; D=-17;
/I:         I=-17; DM=-42;
/M: SY='E';  M= -30, -75, -23,  48, -77, -17,  44, -69,  21, -73, -66,  28, -67,  11, -15,  17,  18,   6, -86, -67; D=-17;
/I:         I=-17; DM=-42;
/M: SY='I';  M= -62,  28, -77, -15,  35, -83, -74,  55,  -3,  20,  12, -72, -76, -70, -70, -67,  -1,  45, -72, -52;
/M: SY='H';  M= -64, -77, -52,  26, -69, -71, 100, -75,  14, -28, -59,  18, -67,   9,  47, -54,  29, -72, -83, -12;
/M: SY='N';  M= -64,  28, -57,  29,  18, -72,  29,  -1,  31, -28,   1,  40,  20, -53,  26, -60, -59,   1,   8, -14;
/M: SY='V';  M= -55, -68, -84, -78, -52, -86, -85,  51, -76, -18, -40, -78, -78, -77, -78, -68, -52,  91, -84, -60;
/M: SY='R';  M= -64, -80, -60, -48, -77, -73, -54, -81,  65, -76, -65, -53, -70, -40,  97, -11, -61, -75, -75, -63;
/M: SY='D';  M= -34, -72,  59, -50, -72,  -3, -58, -70,  23, -15,  -7,  39, -67, -53,  -6,  35,  28, -68,  39, -64;
/M: SY='V';  M= -58, -70, -80, -76,  32, -82, -65, -29, -72, -43, -45, -77, -81, -73, -72, -67, -56,  84, -57,  79;
/M: SY='A';  M=  71, -63, -62, -58, -75,  -5, -65, -70, -10, -72, -65, -53, -65, -54, -62,  67, -12, -59, -78, -69;
/M: SY='P';  M= -65, -88, -65, -55, -84, -67, -68, -73, -22, -83, -70, -29, 123, -64, -71, -24, -12, -77, -80, -81;
/M: SY='H';  M= -60, -75,   4, -54, -74,  29,  67, -77,  36, -41,   3,  56, -69, -49,  41,   0, -24, -75, -83, -61;
/M: SY='K';  M= -60, -75, -61, -13, -69, -74, -64,  13,  90, -61, -56, -55, -67,  -5, -36, -60, -56,  41, -76, -64;
/M: SY='W';  M= -39, -79,  38,  -6,   7, -69, -58, -63, -19, -34, -61,  -5, -21,  38,   7,   5, -17,  -3,  97,  51;
/M: SY='M';  M= -63, -73, -70, -65, -55, -74,  92, -14, -11, -40, 122, -14, -71, -54, -58, -65, -61, -21, -78,   1;
/M: SY='Y';  M= -65,   8, -79, -77,  38, -82, -11,  27, -72,  20,  25, -75, -81, -70, -71, -69, -60,  42, -53,  82;
/M: SY='C';  M=  -8, 125, -76, -71, -67, -76, -74, -55, -22, -61, -60, -67, -83, -69,  39, -62, -58,  44, -90, -72;
/M: SY='V';  M=  19,  -7, -80, -75, -49, -31, -74,  45, -74,  38, -40, -75, -77, -71, -75, -65, -57,  56, -73,  14;
/M: SY='D';  M= -55, -73,  81,  29, -80, -61, -56, -77, -52, -77, -73, -42, -63,  -5, -19,  58,  33, -71, -89, -68;
/M: SY='F';  M= -23, -70, -82, -79,  97, -80, -70,  10, -75,  19, -45, -18, -81, -80, -75, -69, -19,  24, -54, -33;
/M: SY='E';  M= -61, -79,   5,  61, -27, -71, -54, -44,  34, -74, -66,  -9, -13,  40,  58,  -7, -20, -73, -77, -65;
/M: SY='C';  M= -62,  82, -81, -77,  -2, -81, -75,  34, -76,  47,  17, -73, -81, -74, -77,  -5,  -1,  21, -79, -59;
/M: SY='P';  M= -18,  22, -16,   2,  -6, -70, -67,  -7, -22, -10, -61,  15,  90, -62, -13, -25, -58, -12, -79, -70;
/M: SY='K';  M=   2, -76,  -1,  25,   6, -73, -66, -20,  28, -13, -61, -62,  10, -57,   6,  11,  -9,  12, -76,  -7;
/I:         E1=0; IE=-380; DE=-380;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2019_10 which contains 561'356 sequence entries.


Total number of hits 76 in 76 different sequences
Number of true positive hits 76 in 76 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Archaea, Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] SAM-dependent MTase TRM5/TYW2-type
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
76 sequences

TAW21_SACS2 (Q97W08    ), TAW22_NANEQ (Q74NE4    ), TAW22_PYRAB (Q9V2G1    ), 
TRM51_ARATH (Q93YU6    ), TRM51_PHATC (B7FTW3    ), TRM51_TRYCC (Q4CNL4    ), 
TRM51_VITVI (F6H2F8    ), TRM52_ARATH (Q6NQ64    ), TRM52_PHATC (B7G5J1    ), 
TRM52_TRYCC (Q4DPN8    ), TRM52_VITVI (F6HH45    ), TRM5B_METJA (Q58293    ), 
TRM5B_PYRAB (Q9V0Q0    ), TRM5_AEDAE  (Q16VC0    ), TRM5_AJECG  (C0NUP2    ), 
TRM5_ANODA  (E3WPP8    ), TRM5_ANOGA  (Q7Q5Z3    ), TRM5_ASPFU  (Q4WX30    ), 
TRM5_BATDJ  (F4NUJ6    ), TRM5_BOVIN  (Q3MHN8    ), TRM5_CAEEL  (A8WHT1    ), 
TRM5_CANAL  (Q59TN1    ), TRM5_CANAW  (C4YH95    ), TRM5_CIOIN  (F7A355    ), 
TRM5_COPC7  (A8N339    ), TRM5_CRYNJ  (Q5KBP2    ), TRM5_DANRE  (B8A5G9    ), 
TRM5_DICDI  (Q54WD6    ), TRM5_DROME  (Q8IRE4    ), TRM5_DROPS  (B5DPF1    ), 
TRM5_EMENI  (C8VJ35    ), TRM5_ENCCU  (Q8SVV3    ), TRM5_ENTHI  (C4M572    ), 
TRM5_GIAIC  (A8B4Q0    ), TRM5_HUMAN  (Q32P41    ), TRM5_LEIBR  (A4H8F7    ), 
TRM5_LEIIN  (A4HWT0    ), TRM5_LEIMA  (Q4QEY9    ), TRM5_MACFA  (Q95KJ2    ), 
TRM5_MACMU  (F7GSQ4    ), TRM5_MOUSE  (Q9D0C4    ), TRM5_NECH7  (C7YK87    ), 
TRM5_NEUCR  (F5HAU9    ), TRM5_PARTE  (A0CC46    ), TRM5_PEDHC  (E0VLV0    ), 
TRM5_PHANO  (Q0UVC3    ), TRM5_PHYIT  (D0NLC2    ), TRM5_PHYPA  (A9T6G5    ), 
TRM5_PLAF7  (C0H537    ), TRM5_PLAKH  (B3L2G0    ), TRM5_PLAVS  (A5K6L0    ), 
TRM5_POLPP  (D3BT31    ), TRM5_PUCGT  (E3KWE1    ), TRM5_SCHPO  (Q8TFG7    ), 
TRM5_SORBI  (C5XX79    ), TRM5_THAPS  (B8BQY5    ), TRM5_THEAN  (Q4UB74    ), 
TRM5_THEPA  (Q4MYY2    ), TRM5_TRIVA  (A2E5K9    ), TRM5_TUBMM  (D5GN29    ), 
TRM5_USTMA  (Q4PHW2    ), TRM5_XENTR  (F6VSS6    ), TRM5_YARLI  (Q6CA67    ), 
TRM5_YEAST  (P38793    ), TYW23_ARATH (Q8W4K1    ), TYW23_ORYSJ (Q8H4D4    ), 
TYW2_BOVIN  (Q58D65    ), TYW2_DANRE  (Q0P466    ), TYW2_HUMAN  (Q53H54    ), 
TYW2_MACFA  (Q4R3U8    ), TYW2_METJA  (Q58952    ), TYW2_MOUSE  (Q8BG71    ), 
TYW2_PYRHO  (O58523    ), TYW2_RAT    (Q4V8B8    ), TYW2_SCHPO  (Q09832    ), 
TYW2_YEAST  (Q04235    )
» more

PDB
[Detailed view]
15 PDB

2YX1; 2ZZM; 2ZZN; 3A25; 3A26; 3A27; 3AY0; 3K6R; 5HJI; 5HJJ; 5HJK; 5HJM; 5WT1; 5WT3; 5YAC
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View entry in raw text format (no links)
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