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annotation rule: PRU01021

General rule information [?]

Accession PRU01021
Dates 21-AUG-2013 (Created)
22-NOV-2019 (Last updated, Version 4)
Data class Domain
Predictors PROSITE; PS51684; SAM_MT_TRM5_TYW2
Name tRNA (guanine(37)-N(1))-methyltransferase (EC
Function tRNA (guanine(37)-N(1))-methyltransferase (EC is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to guanine(37) in tRNA to form N(1)-methylguanine(37) in tRNA and S-adenosyl-L- homocysteine.

Propagated annotation [?]

Description [?]

+ RecName: EC 2.1.1.-;

Comments [?]

Similarity Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.

Gene Ontology [?]

GO:0032259; Biological process: methylation.

Keywords [?]

Features [?]

From: PS51684
Key     From     To       Description   Tag   Condition   FTGroup
REGION     128     129       S-adenosyl-L-methionine binding     [DE]-[ILM]  
REGION     156     157       S-adenosyl-L-methionine binding     [DE]-[AGNSV]  
BINDING     90     90       S-adenosyl-L-methionine     [HKR]  
BINDING     180     180       S-adenosyl-L-methionine     N  

Additional information [?]

Size range 229-457 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q4DPN8 (TRM52_TRYCC)
Archaea; Euryarchaeota
Comments None


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UniProtKB rule member sequences [?]