ProRule PRU01021
General rule information
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| Accession | PRU01021 |
| Dates | 21-AUG-2013 (Created)
8-OCT-2024 (Last updated, Version 8) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51684; SAM_MT_TRM5_TYW2 |
Name | tRNA (guanine(37)-N(1))-methyltransferase (EC 2.1.1.228) |
| Function | tRNA (guanine(37)-N(1))-methyltransferase (EC 2.1.1.228) is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to guanine(37) in tRNA to form N(1)-methylguanine(37) in tRNA and S-adenosyl-L- homocysteine. |
| Scope(s) |
Eukaryota Archaea Methanobacteriati |
| Example(s) | Q4DPN8 (TRM52_TRYCC); |
Propagated annotation
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Identifier, protein and gene names
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| Protein name | + RecName: EC=2.1.1.-; |
Comments
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| SIMILARITY | Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family. |
Keywords
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Gene Ontology
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| GO:0032259; Biological process:methylation |
Features
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| From: PS51684 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 128 | 129 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
[DE]-[ILM] | ||||||||
| BINDING | 156 | 157 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
[DE]-[AGNSV] | ||||||||
| BINDING | 90 | 90 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
[HKR] | ||||||||
| BINDING | 180 | 180 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
N | ||||||||
Additional information
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| Size range | 229-457 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Archaea [7] Eukaryota [69] All [ 76 ]
- Retrieve set of proteins with 3D structure for this domain