ProRule PRU01021

General rule information [?]

Accession PRU01021
Dates 21-AUG-2013 (Created)
19-NOV-2022 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51684; SAM_MT_TRM5_TYW2
Name tRNA (guanine(37)-N(1))-methyltransferase (EC
Function tRNA (guanine(37)-N(1))-methyltransferase (EC is an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to guanine(37) in tRNA to form N(1)-methylguanine(37) in tRNA and S-adenosyl-L- homocysteine.
Scope(s) Eukaryota
Example(s) Q4DPN8 (TRM52_TRYCC);

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name + RecName: EC=2.1.1.-;

Comments [?]

SIMILARITYBelongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.

Keywords [?]

Gene Ontology [?]

GO:0032259; Biological process:methylation

Features [?]

From: PS51684
Key From To Description Tag Condition FTGroup
BINDING 128 129 /ligand="S-adenosyl-L-methionine"
BINDING 156 157 /ligand="S-adenosyl-L-methionine"
BINDING 90 90 /ligand="S-adenosyl-L-methionine"
BINDING 180 180 /ligand="S-adenosyl-L-methionine"

Additional information [?]

Size range 229-457 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]