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Entry: PS51699

General information about the entry

Entry name [info] SEA_DG
Accession [info] PS51699
Entry type [info] MATRIX
Date [info] 01-JAN-2014 CREATED;
10-MAY-2017 DATA UPDATE;
13-NOV-2019 INFO UPDATE.
PROSITE Doc. [info] PDOC51699
Associated ProRule [info] PRU01036

Name and characterization of the entry

Description [info] DG-type SEA domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=112;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=107;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3419399; R2=0.0086905; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=19481.0000000; R2=0.0000000; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=939; H_SCORE=19481; N_SCORE=10.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=479; H_SCORE=19481; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-36; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='P';  M=   5,  -8, -26,  21, -21, -33,  15, -18,  -7, -50,  -1, -44,  51,  16,  -2,  -4,   1, -59,-109,   2;
/M: SY='P';  M= -38,-113,-106,-100,  -3,-108,  21,  24,-101, -35, -88,-104,  80,-101, -51, -33,   1,  10, -22,  57;
/M: SY='N';  M= -71, -22, -38, -90,-107, -92,  22,-107,  17, -60,-101,  94,  16, -87, -90,  22,  19,-106,   1, -25;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='H';  M= -33,-110, -98, -96,  -1,-108, 116, -59, -52,   0, -84, -31, -30, -92, -36, -53, -47,  27,-113,  24;
/M: SY='E';  M= -62,-112, -86,  69, -14, -50, -28,  15,  -5, -13,  10, -41, -39,  19,  15, -20, -40, -30,-110, -97;
/M: SY='F';  M=-105,-107,-118,-114, 101,-117,  10,  10,-110, -19,  26,-109, -40,-114,-108,-106, -40,  -6, -84,  17;
/M: SY='S';  M= -56,-104, -23, -30, -15, -28,  15, -10, -37, -38, -19,  13,-102,  33, -42,  57,  42, -37,-113, -31;
/M: SY='M';  M=  -6,-106,-116,-110,  -9,-114,  12,  50,-108,  43,  78,-108,-111,-102,-107, -53, -94,   1,-106, -22;
/M: SY='T';  M= -29,-105, -48,   9,  -6, -49, -44, -34, -16,  10, -87, -17,-104,   5,   9, -41,  58,  20,-110, -11;
/M: SY='L';  M= -99,-104,-117,-111,  46,-117,-104,  34,-109,  58,  57,-110,-113,-106,-108, -54, -12,   3,-101, -81;
/M: SY='D';  M= -22,-109,  64,  26,-106,-100, -90, -44,  37, -43,-100,  15, -29, -31, -18,   8,   3, -59,-114,   1;
/M: SY='L';  M= -59,-107, -31, -17,  -2, -38,   8,  13,   0,  28,  14,  14, -24, -28, -24, -94,  20,  -6,  12,  24;
/M: SY='P';  M= -58,-111,  56,   5, -48, -40, -16, -43, -52, -54, -23,  34,  64, -14, -51,  -8,  11, -48,-112,  13;
/I:         I=-36; MD=-90;
/M: SY='Y';  M= -63,-111,  -2, -14,  34,-110, -26, -36,   5,  -8, -92,   1, -20, -97, -51, -12,  28, -49, -95,  68; D=-36;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='D';  M= -28, -23,  44,  35, -44, -58, -17, -58,  17,   2, -93,   3,-101,  30,  -4, -11,  -4, -22,  -3, -23;
/M: SY='Q';  M=  13,-106, -39,  24, -38,-100,  -3, -26,  23, -20, -92, -19,  -7,  51,  -5,  11,  27, -47,-109, -33;
/M: SY='F';  M=-100,  12, -46, -12,  90,-110,  12, -19,-103,  -2,  23, -17, -42, -40,-103, -11, -21, -27,  34,  -9;
/M: SY='M';  M=  -4,  -8,  -7, -14, -23, -14,  -9, -53, -39,  -3,  60,  18,  -4,  41, -41,   9,   6,   3,-111, -93;
/M: SY='N';  M= -22,-105, -44,  -4,  17, -10,  39, -14,  21, -67, -94,  66,   1,   3, -16,   3,   3, -38,-111, -92;
/M: SY='D';  M= -27,-104,  66, -42,  17, -93,   2, -51, -12,-103, -11,  60, -34, -15, -92,  32,  21, -58,-116, -93;
/M: SY='P';  M=  20,-104,-106, -99, -43,-105, -23,   6, -53,  12, -81,-103,  59,-100, -29, -36,  -3,  54,  15, -45;
/M: SY='D';  M= -23,-106,  48,  35, -35, -98,  28, -18,  -6, -22, -94,  -7, -51,  12, -22,  34,   6, -33,   6, -41;
/M: SY='W';  M= -32,-107, -35, -28, -85, -59, -19,  -7,   3,  24,  42, -24,-105,  -3,  22, -53,   5,  14,  95,   5;
/M: SY='Q';  M= -53,  25, -93, -28, -45,-104, -89, -25,  35,  -2, -30, -35,-103,  70,  65,  -8, -57, -16,-107, -93;
/M: SY='I';  M= -59, -25, -36, -23, -12, -23, -22,  50, -52,  34,  -2, -44,-106, -94,  32, -11, -20,  16,-106, -32;
/M: SY='K';  M=  19,-105,  13,  25, -48, -17, -90, -17,  35, -23, -36,  23, -99,  19,  17,  -6, -19, -47,   1, -29;
/M: SY='F';  M= -44,-102,-114, -55,  75,-115,-101,  12,-108,  63, -69,-110,-113,-107,-107,-104, -31,   5, -92, -26;
/M: SY='V';  M=   8, -23,-110, -42, -13,-110,-106,  45, -43,  30,  39,-105,-107,-101,-104, -53, -18,  55,   6, -88;
/M: SY='E';  M= -62,-108,  27,  63, -38, -30, -87,-105,  14, -46, -98,  28, -96,   9,  34, -18,  17, -51, -24, -24;
/M: SY='K';  M=  13, -15,  13, -37, -13, -29,  12, -21,  68, -65, -94, -20,-100, -34,  53, -50, -26, -98,-107, -94;
/M: SY='I';  M= -57,-104,-117,-111, -77,-119,-108,  73,-110,  66, -64,-112,-111,-105,-110,-106, -92,  17,-105, -87;
/M: SY='A';  M=  71, -97, -94, -89,-106, -23, -96, -96, -51,-100, -94, -31, -98,  20,   1,  50,   8, -11,-110,-100;
/M: SY='R';  M= -27,-107,  36,  20,   3, -48, -86,-101,  34, -22,  12,  33,-100,  16,  43,  -6, -39,-100,-106,  -5;
/M: SY='Y';  M=  21,-102,-106,-103,  41, -25, -95,  16, -52,  23, -79, -99,-107, -99,-101,  -3,  13,  13, -90,  62;
/M: SY='F';  M=-100,-103,-110,-109,  84, -39, -92, -26,-105,  34,  23, -13,-113,-105,-104,-100, -17,  -3, -82,  63;
/M: SY='G';  M= -55,-107, -25, -92,-112,  77,  11,-116,  19,-114,-103,  56,-100,  -4,   4,  -9, -91,-112,-111,-103;
/M: SY='D';  M= -32,-107,  93,  23,-108, -36, -90,   0, -88, -64, -99, -13, -98, -16, -95,  -4,   5,   2,-123,-100;
/M: SY='P';  M=  -4,-106,  31,   5,-106, -46, -90,-103,   5, -42, -98,  15,  48,  -6,  28,  41,   2, -54,-111, -25;
/M: SY='D';  M= -55,-105,  64, -17, -21, -35, -91,  15, -46, -97,  -2,  54,  19, -89, -96,  26,  -5,  -6,   7, -33;
/I:         I=-26; MD=-67;
/M: SY='T';  M=  -4,  18,-108, -29, -38,-113, -39,  -1,-107, -43,  27, -20,  16,-107,-112, -19,  55,   6,-125,-107; D=-26;
/I:         I=-26; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='S';  M= -58,-110,  40, -15,-114, -35,  10, -44,  16, -66,-104,  18,  -6,  22, -25,  61, -53,-107,-120,-103; D=-26;
/I:         I=-26; DM=-67;
/M: SY='N';  M=  21,-105,  23, -28, -16, -95,  29, -10, -29, -66,  19,  53,-103,  13, -11,  20, -18, -95,-107,  30; D=-26;
/I:         I=-26; DM=-67;
/M: SY='I';  M= -97,-107,-116, -51,  29,-120,-110,  83,-108,  27, -70,-110,-110,-106, -39,-105, -92,  28,-102, -25; D=-26;
/I:         I=-26; DM=-67;
/M: SY='T';  M= -37, -10, -27, -24, -32,-100, -21,   0, -87, -26, -10, -12, -98,  29,   3,  19,  73,  15,  -2, -10;
/M: SY='V';  M= -17,-101,-111, -52,   0,-113, -24,  58,-105,  21,  -7,-106, -35,-104,-107, -98, -46,  71,-108, -87;
/M: SY='R';  M= -23,-105,   1, -28, -95,-104,  31,  12,  15,  19, -19, -30,-102,  22,  58, -28,   4,   5,-110, -91;
/M: SY='S';  M=   1,-102,  14,   8,-103, -13,  21,-106,  21,-106, -98,  46, -18, -29,   2,  57,  -7,-101,-109,   9;
/M: SY='I';  M=  -9,-103,-115,-110,  45,-113,-106,  75,-107,  15,  19,-107,-108,-105,-107,-101, -90,  35,  11,   7;
/M: SY='N';  M= -62,-102,   8,   6,   8, -19, -23,-102,   1, -62, -27,  48, -33,  -8,  39,  36,  42, -98,-109, -36;
/M: SY='P';  M=   1,-106, -85,  26, -33, -28,  -7, -36,  16, -42, -93,  28,  39,  39,  23,  20, -15, -98,-104,  10;
/I:         I=-25; MD=-63;
/M: SY='T';  M= -61,-121,   7, -25, -22, -62, -26, -44,  14, -59, -29,  19,-119,-107,-107, -30,  22,   7,-127,  -7; D=-25;
/I:         I=-25; MI=0; MD=-63; IM=0; DM=-63;
/M: SY='R';  M= -61,-125,   7, -40, -21,  16,-108,-125, -26,-125,-117,  13,  11, -39,  36,  -5, -21, -66,-128,-115; D=-25;
/I:         I=-25; DM=-63;
/M: SY='N';  M= -35,-106,  39, -14,-109,  63,  40, -59, -42, -66,-101,  65,  -9, -86, -24,  -7, -89,-108,-115,-100;
/M: SY='S';  M= -57,-102, -31, -45,-100,  18, -17, -47, -27, -49,   4, -82,  25,  25,   2,  72,  22, -96,-106,   9;
/M: SY='T';  M= -25, -27,-101, -99,  15, -56, -11,  22, -39, -32, -81, -93, -38, -98, -50, -24,  72,  52,  12,  -4;
/M: SY='T';  M= -91,-103, -34,  -2,   1,-107, -95,  42, -89, -37,  18,  13,-102,  -8,  20, -57,  45,  38,  17,  19;
/M: SY='F';  M= -48,-102,-115,-110,  68,-115,-103,  57,-107,  21,   6,-108,-111,-107,-107,-102, -90,  48, -92,  18;
/M: SY='T';  M= -16, -98, -88,  16, -33, -35, -94, -22,   6, -95, -23, -17, -95, -28, -15,  54,  67,  11,-112, -95;
/M: SY='W';  M=-105,-116,-124,-111,  80,-108,-111, -52,-105, -50, -92,-116,-112,-107,-106, -47,-106, -53, 156,  22;
/M: SY='T';  M= -48,-100, -94, -95,  51, -56,  59, -92, -91, -90,  -9, -42,-100, -91, -25,  35,  74, -90,  18,  52;
/M: SY='N';  M= -95,-100,   6, -89,  21, -87,  15, -30, -83, -46, -94, 117,-105, -85, -90, -80, -81, -29,-118, -92;
/M: SY='N';  M=  -1,  50,  41,  -1,-104, -39,  17,-102,   6, -44, -96,  72, -29, -84,  -7, -45,  29, -48,-117, -31;
/M: SY='T';  M= -44, -95, -87, -45,-102, -16, -94, -48, -88,-100, -95,   2, -93, -34, -95,  73,  86, -43,-115, -97;
/I:         I=-42; MI=0; MD=-106; IM=0; DM=-106;
/M: SY='L';  M= -49,-102,-110,-106, -76,-113, -18,  51, -50,  74, -28, -12,-110,-100,-104, -57, -91,  -1,-103, -21;
/I:         I=-28; MI=0; MD=-70; IM=0; DM=-70;
/M: SY='P';  M= -34,-112,  13, -24, -52, -97, -96, -46,   3,-109,-100,  10,  98,  -4, -95,  29, -37, -31,-113,-105; D=-28;
/I:         I=-28; DM=-70;
/M: SY='T';  M=  10,-103, -49, -24,  -8, -68,   2, -52,  30,  -5, -32, -41, -43, -44,  19,  -7,  53, -32,-101,  41; D=-28;
/I:         I=-28; MI=0; MD=-70; IM=0; DM=-70;
/M: SY='E';  M= -12,-104,  40,  51,-106, -36,   4,-106,  38, -59, -98,  31, -94, -32, -42,  30,  22,-101,-112, -25;
/M: SY='P';  M= -26,-108,  24,  11, -97, -17,   1, -97, -14, -44, -94, -41,  55,   9,  22,   3,  19,  -9,  37,  31;
/M: SY='C';  M= -92, 156,-111,-110,-103,-107,-111,-109,-106,-100,-100, -98, -41, -27,-113, -94, -92, -97,-131,-112;
/M: SY='P';  M= -66, -18,  46, -19,-111, -95, -90,-105, -88, -68, -29,  50, 104,  -6, -98, -30, -87,-107,-114, -33;
/M: SY='N';  M= -32,-104,   4,  18, -38, -55,  40,  -4,  18, -95,   7,  43, -52,  -4,  34,   9,  14, -22,-105,  26;
/M: SY='E';  M= -10,-105,  35,  52,-108, -32, -20, -53,  48,-105, -98,  18,  21, -38,   9, -12,  17, -55,-111, -99;
/M: SY='E';  M=  11,-104,  26,  61,-103, -53,   9, -45,  35,  -3, -25, -83, -94,  23, -14,  -1,  12, -94,-109, -95;
/M: SY='I';  M= -94,-104,-112, -32, -14,-117,-106,  88,-105,  41, -66,-107,-107,-102, -48,-103, -89,  21,-100,   0;
/M: SY='E';  M=  -8,  -8,  43,  45,-104, -29,  24, -10, -47, -31, -93,  33, -96,  23,   6,  13,  22, -46,-114, -96;
/M: SY='Q';  M=  21,-106,  -3,  35,-104, -45,   8,-103,  40, -45, -23, -17, -35,  54,  29,   2, -43, -66,-105,   0;
/M: SY='L';  M= -38,-101, -37,-104, -77,-112,-100,  36,-104,  70,  55, -56,-109, -33,-104, -60, -21,   6,  17, -85;
/M: SY='R';  M= -30,-105,-100, -56,  -7, -39, -92,  30,  -9,  26,  22,   3,-105, -10,  41, -11, -11, -16,  34,  38;
/M: SY='N';  M= -10,-102, -25,  24,-105, -35, -24,-101,  39, -44, -95,  54, -97, -15,  32,  42,   2, -28,-112, -97;
/M: SY='K';  M= -47,-105, -96, -45, -14, -48, -91,  16,  65,  -7,  30,  -9,-102, -34,  41, -92, -35,  15,-100,  19;
/M: SY='M';  M= -59,-101,-115,-108,  43, -62, -97,  32,-106,  65,  88,-108,-110,-100,-104,-104, -93, -70, -96, -29;
/M: SY='F';  M=  -6,-102, -45, -20,  37,   8,  -8,  15,   1,   8, -32, -30,-103, -93,  -7, -12,  14,  28,-100,   2;
/I:         I=-16; MI=0; MD=-40; IM=0; DM=-40;
/M: SY='D';  M= -57,-117,  43, -28,-117,  -5,  10, -53,  13,-118,-111,  38, -31, -96, -16,   3,   8, -62,-126, -14; D=-16;
/I:         I=-16; DM=-40;
/M: SY='D';  M= -60,-113,  47,  11, -35, -15, -20, -13,  -9, -69,-101,  24,  23,  36, -13,  -4,  -3, -41,-119,-102; D=-16;
/I:         I=-16; DM=-40;
/M: SY='D';  M= -63,-110,  59,   4,-110,  22, -91, -46,  24, -60,-103,  34,   5, -85,  19,   6, -27,-107,-115, -26; D=-16;
/I:         I=-16; DM=-40;
/M: SY='G';  M= -25,-109,  29,   2,-111,  65,   3, -48,  -5, -65, -28,  14,-101, -88,  22,   2, -46,-107,-113,-103; D=-16;
/I:         I=-16; DM=-40;
/M: SY='K';  M= -42,-107,  -9, -18,-106,  17, -18, -51,  50, -30, -15,  11, -29,  13,  23,   7,  12, -14,-112, -99; D=-16;
/I:         I=-16; DM=-40;
/M: SY='P';  M= -33,-107,-106, -97, -94, -42,-104,  11,-100,  23, -31,-103,  75,  13,-104,  -8, -24,  47,-112, -98; D=-16;
/I:         I=-16; DM=-40;
/M: SY='S';  M= -52, -99, -83, -28,-102, -91,  -8, -28,  32, -43, -94,  57, -97, -80,  26,  59,  52, -94,-114, -96;
/M: SY='Q';  M=   5,-107,  26,  31,-110, -55, -28, -52,   3,-104, -16,   9,  50,  60, -18,  18,  10,-100,-111, -99;
/M: SY='E';  M=  33,-103, -14,  52,-107, -35,  20, -66,  15, -70, -95,  22, -95,  15,  11,  26, -17, -24,-111, -97;
/M: SY='F';  M= -32, -10,-115,-109,  89,-112,-102,   0,-107,  47, -72,-108,-113,-109,-106, -33, -92,  29, -89, -68;
/M: SY='T';  M= -34,-102,   0, -44, -12, -52, -14,  17,  40, -48, -26, -39, -99,  15, -10,  27,  42,  20,-106,  -9;
/M: SY='R';  M= -12,-105,  31,  19,-106, -32, -22,-102,  32, -30, -95,  39, -98,  30,  42,  18,  -1, -39,-112, -97;
/I:         I=-28; MD=-70;
/M: SY='A';  M=  71, -98, -96, -26, -49, -92, -97,  -8,  16, -31, -87, -20,-100,  13, -36, -42,   1,  20,-107, -26; D=-28;
/I:         I=-28; MD=-70;
/M: SY='M';  M= -98,-102,-117,-109,  56,-114, -96, -25,-106,  53, 108,-109,-111,-101,-104,-106, -94, -13, -97, -76; D=-28;
/I:         I=-28; MI=0; MD=-70; IM=0; DM=-70;
/M: SY='G';  M= -13,-104, -29,   1, -39,  39, -94,   4,  20,  16, -86, -11, -10,   3, -19,   1,  18, -44,-105, -21;
/M: SY='P';  M= -25,-111, -33, -10, -48, -59, -34, -46,   1, -52, -96,  14, 104,  -3, -94,  13, -27, -49,-110,-104;
/M: SY='E';  M= -46, -18,  54,  71, -33, -12, -86,-106, -13, -39, -14,   8, -15,  15,   4, -25, -37,-103,-109, -11;
/M: SY='F';  M=-102,-104,-112,-110,  98,-113, -22,   9,-105,   7, -77, -46,-114,-107,-103,-102, -95,  -3, -75,  76;
/M: SY='P';  M= -27,-105, -88, -16,-101, -38,  30, -25,  15, -30, -25,  40,  57, -15,  14,  19,  22,  -3,-111, -37;
/M: SY='V';  M= -42,-102, -37, -50, -86, -18,-109,  52,-104,  10, -15,-104,  14,-103,-107, -97, -36,  76,-111, -92;
/M: SY='T';  M= -36,-103,   1, -17, -97, -33,   6,   3,  30, -11, -32, -38, -98,  20,  23,  18,  47,   5,-109, -23;
/M: SY='S';  M= -83,-103,  22, -11,-108,  23, -20, -57,  11, -74, -99,  26, -97,  15,  27,  71, -40,-102,-112, -98;
/M: SY='V';  M=  10,-100,-109,-105, -18,   9,-108,  37,-103,  -4, -21,-102, -33,-103,-106, -49, -41,  75,-108, -20;
/M: SY='S';  M= -41,-102, -13,  26, -19, -23,   1, -30,  22, -99, -27, -40, -96,  14,   2,  56,  42, -38,  13, -22;
/M: SY='W';  M= -18,-103,  -9, -99,  43, -39, -22, -13, -33,  35,  17,-100,   4, -99, -28, -55,  -4,  36,  47,  10;
/M: SY='Q';  M= -12,-103, -44,  44, -51, -31, -26,  15,   6, -42, -42,  12, -39,  44, -47,  17,  33,  -5,-108, -28;
/M: SY='P';  M= -22,-107, -99, -39,  -9,  26, -96, -19, -46,   3, -88, -94,  60, -11,  21,   4,   3,  -6,  44,  18;
/M: SY='I';  M= -17,-102, -21, -47,  11,-104,  -2,  41, -21,  21,  37, -93,-103, -40,  -8,  28,  25, -23,-102,   8;
/M: SY='G';  M= -28,  25, -91,  12,-108,  84, -98, -25,  -1, -26, -98,   3,-100, -36, -98, -49, -44,-103,-108,-105;
/M: SY='S';  M=   8,  -7,  16, -11,-102, -56, -19,   8, -13, -21, -25,  34,  33,  22, -93,  37,  -7,  -7,-113, -98;
/I:         E1=0; IE=-380; DE=-380;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2019_10 which contains 561'356 sequence entries.


Total number of hits 6 in 6 different sequences
Number of true positive hits 6 in 6 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] Peptidase S72
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
6 sequences

DAG1_BOVIN  (O18738    ), DAG1_CANLF  (Q9TSZ6    ), DAG1_HUMAN  (Q14118    ), 
DAG1_MOUSE  (Q62165    ), DAG1_PIG    (Q29243    ), DAG1_RABIT  (Q28685    )
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View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission