PROSITE entry PS51699
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General information about the entry
| Entry name [info] | SEA_DG |
| Accession [info] | PS51699 |
| Entry type [info] | MATRIX |
| Date [info] |
01-JAN-2014 CREATED;
10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51699 |
| Associated ProRule [info] | PRU01036 |
Name and characterization of the entry
| Description [info] | DG-type SEA domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=112; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=107; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3419399; R2=0.0086905; TEXT='-LogE'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=19481.0000000; R2=0.0000000; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=939; H_SCORE=19481; N_SCORE=10.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=479; H_SCORE=19481; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-36; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='P'; M= 5, -8, -26, 21, -21, -33, 15, -18, -7, -50, -1, -44, 51, 16, -2, -4, 1, -59,-109, 2; /M: SY='P'; M= -38,-113,-106,-100, -3,-108, 21, 24,-101, -35, -88,-104, 80,-101, -51, -33, 1, 10, -22, 57; /M: SY='N'; M= -71, -22, -38, -90,-107, -92, 22,-107, 17, -60,-101, 94, 16, -87, -90, 22, 19,-106, 1, -25; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='H'; M= -33,-110, -98, -96, -1,-108, 116, -59, -52, 0, -84, -31, -30, -92, -36, -53, -47, 27,-113, 24; /M: SY='E'; M= -62,-112, -86, 69, -14, -50, -28, 15, -5, -13, 10, -41, -39, 19, 15, -20, -40, -30,-110, -97; /M: SY='F'; M=-105,-107,-118,-114, 101,-117, 10, 10,-110, -19, 26,-109, -40,-114,-108,-106, -40, -6, -84, 17; /M: SY='S'; M= -56,-104, -23, -30, -15, -28, 15, -10, -37, -38, -19, 13,-102, 33, -42, 57, 42, -37,-113, -31; /M: SY='M'; M= -6,-106,-116,-110, -9,-114, 12, 50,-108, 43, 78,-108,-111,-102,-107, -53, -94, 1,-106, -22; /M: SY='T'; M= -29,-105, -48, 9, -6, -49, -44, -34, -16, 10, -87, -17,-104, 5, 9, -41, 58, 20,-110, -11; /M: SY='L'; M= -99,-104,-117,-111, 46,-117,-104, 34,-109, 58, 57,-110,-113,-106,-108, -54, -12, 3,-101, -81; /M: SY='D'; M= -22,-109, 64, 26,-106,-100, -90, -44, 37, -43,-100, 15, -29, -31, -18, 8, 3, -59,-114, 1; /M: SY='L'; M= -59,-107, -31, -17, -2, -38, 8, 13, 0, 28, 14, 14, -24, -28, -24, -94, 20, -6, 12, 24; /M: SY='P'; M= -58,-111, 56, 5, -48, -40, -16, -43, -52, -54, -23, 34, 64, -14, -51, -8, 11, -48,-112, 13; /I: I=-36; MD=-90; /M: SY='Y'; M= -63,-111, -2, -14, 34,-110, -26, -36, 5, -8, -92, 1, -20, -97, -51, -12, 28, -49, -95, 68; D=-36; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='D'; M= -28, -23, 44, 35, -44, -58, -17, -58, 17, 2, -93, 3,-101, 30, -4, -11, -4, -22, -3, -23; /M: SY='Q'; M= 13,-106, -39, 24, -38,-100, -3, -26, 23, -20, -92, -19, -7, 51, -5, 11, 27, -47,-109, -33; /M: SY='F'; M=-100, 12, -46, -12, 90,-110, 12, -19,-103, -2, 23, -17, -42, -40,-103, -11, -21, -27, 34, -9; /M: SY='M'; M= -4, -8, -7, -14, -23, -14, -9, -53, -39, -3, 60, 18, -4, 41, -41, 9, 6, 3,-111, -93; /M: SY='N'; M= -22,-105, -44, -4, 17, -10, 39, -14, 21, -67, -94, 66, 1, 3, -16, 3, 3, -38,-111, -92; /M: SY='D'; M= -27,-104, 66, -42, 17, -93, 2, -51, -12,-103, -11, 60, -34, -15, -92, 32, 21, -58,-116, -93; /M: SY='P'; M= 20,-104,-106, -99, -43,-105, -23, 6, -53, 12, -81,-103, 59,-100, -29, -36, -3, 54, 15, -45; /M: SY='D'; M= -23,-106, 48, 35, -35, -98, 28, -18, -6, -22, -94, -7, -51, 12, -22, 34, 6, -33, 6, -41; /M: SY='W'; M= -32,-107, -35, -28, -85, -59, -19, -7, 3, 24, 42, -24,-105, -3, 22, -53, 5, 14, 95, 5; /M: SY='Q'; M= -53, 25, -93, -28, -45,-104, -89, -25, 35, -2, -30, -35,-103, 70, 65, -8, -57, -16,-107, -93; /M: SY='I'; M= -59, -25, -36, -23, -12, -23, -22, 50, -52, 34, -2, -44,-106, -94, 32, -11, -20, 16,-106, -32; /M: SY='K'; M= 19,-105, 13, 25, -48, -17, -90, -17, 35, -23, -36, 23, -99, 19, 17, -6, -19, -47, 1, -29; /M: SY='F'; M= -44,-102,-114, -55, 75,-115,-101, 12,-108, 63, -69,-110,-113,-107,-107,-104, -31, 5, -92, -26; /M: SY='V'; M= 8, -23,-110, -42, -13,-110,-106, 45, -43, 30, 39,-105,-107,-101,-104, -53, -18, 55, 6, -88; /M: SY='E'; M= -62,-108, 27, 63, -38, -30, -87,-105, 14, -46, -98, 28, -96, 9, 34, -18, 17, -51, -24, -24; /M: SY='K'; M= 13, -15, 13, -37, -13, -29, 12, -21, 68, -65, -94, -20,-100, -34, 53, -50, -26, -98,-107, -94; /M: SY='I'; M= -57,-104,-117,-111, -77,-119,-108, 73,-110, 66, -64,-112,-111,-105,-110,-106, -92, 17,-105, -87; /M: SY='A'; M= 71, -97, -94, -89,-106, -23, -96, -96, -51,-100, -94, -31, -98, 20, 1, 50, 8, -11,-110,-100; /M: SY='R'; M= -27,-107, 36, 20, 3, -48, -86,-101, 34, -22, 12, 33,-100, 16, 43, -6, -39,-100,-106, -5; /M: SY='Y'; M= 21,-102,-106,-103, 41, -25, -95, 16, -52, 23, -79, -99,-107, -99,-101, -3, 13, 13, -90, 62; /M: SY='F'; M=-100,-103,-110,-109, 84, -39, -92, -26,-105, 34, 23, -13,-113,-105,-104,-100, -17, -3, -82, 63; /M: SY='G'; M= -55,-107, -25, -92,-112, 77, 11,-116, 19,-114,-103, 56,-100, -4, 4, -9, -91,-112,-111,-103; /M: SY='D'; M= -32,-107, 93, 23,-108, -36, -90, 0, -88, -64, -99, -13, -98, -16, -95, -4, 5, 2,-123,-100; /M: SY='P'; M= -4,-106, 31, 5,-106, -46, -90,-103, 5, -42, -98, 15, 48, -6, 28, 41, 2, -54,-111, -25; /M: SY='D'; M= -55,-105, 64, -17, -21, -35, -91, 15, -46, -97, -2, 54, 19, -89, -96, 26, -5, -6, 7, -33; /I: I=-26; MD=-67; /M: SY='T'; M= -4, 18,-108, -29, -38,-113, -39, -1,-107, -43, 27, -20, 16,-107,-112, -19, 55, 6,-125,-107; D=-26; /I: I=-26; MI=0; MD=-67; IM=0; DM=-67; /M: SY='S'; M= -58,-110, 40, -15,-114, -35, 10, -44, 16, -66,-104, 18, -6, 22, -25, 61, -53,-107,-120,-103; D=-26; /I: I=-26; DM=-67; /M: SY='N'; M= 21,-105, 23, -28, -16, -95, 29, -10, -29, -66, 19, 53,-103, 13, -11, 20, -18, -95,-107, 30; D=-26; /I: I=-26; DM=-67; /M: SY='I'; M= -97,-107,-116, -51, 29,-120,-110, 83,-108, 27, -70,-110,-110,-106, -39,-105, -92, 28,-102, -25; D=-26; /I: I=-26; DM=-67; /M: SY='T'; M= -37, -10, -27, -24, -32,-100, -21, 0, -87, -26, -10, -12, -98, 29, 3, 19, 73, 15, -2, -10; /M: SY='V'; M= -17,-101,-111, -52, 0,-113, -24, 58,-105, 21, -7,-106, -35,-104,-107, -98, -46, 71,-108, -87; /M: SY='R'; M= -23,-105, 1, -28, -95,-104, 31, 12, 15, 19, -19, -30,-102, 22, 58, -28, 4, 5,-110, -91; /M: SY='S'; M= 1,-102, 14, 8,-103, -13, 21,-106, 21,-106, -98, 46, -18, -29, 2, 57, -7,-101,-109, 9; /M: SY='I'; M= -9,-103,-115,-110, 45,-113,-106, 75,-107, 15, 19,-107,-108,-105,-107,-101, -90, 35, 11, 7; /M: SY='N'; M= -62,-102, 8, 6, 8, -19, -23,-102, 1, -62, -27, 48, -33, -8, 39, 36, 42, -98,-109, -36; /M: SY='P'; M= 1,-106, -85, 26, -33, -28, -7, -36, 16, -42, -93, 28, 39, 39, 23, 20, -15, -98,-104, 10; /I: I=-25; MD=-63; /M: SY='T'; M= -61,-121, 7, -25, -22, -62, -26, -44, 14, -59, -29, 19,-119,-107,-107, -30, 22, 7,-127, -7; D=-25; /I: I=-25; MI=0; MD=-63; IM=0; DM=-63; /M: SY='R'; M= -61,-125, 7, -40, -21, 16,-108,-125, -26,-125,-117, 13, 11, -39, 36, -5, -21, -66,-128,-115; D=-25; /I: I=-25; DM=-63; /M: SY='N'; M= -35,-106, 39, -14,-109, 63, 40, -59, -42, -66,-101, 65, -9, -86, -24, -7, -89,-108,-115,-100; /M: SY='S'; M= -57,-102, -31, -45,-100, 18, -17, -47, -27, -49, 4, -82, 25, 25, 2, 72, 22, -96,-106, 9; /M: SY='T'; M= -25, -27,-101, -99, 15, -56, -11, 22, -39, -32, -81, -93, -38, -98, -50, -24, 72, 52, 12, -4; /M: SY='T'; M= -91,-103, -34, -2, 1,-107, -95, 42, -89, -37, 18, 13,-102, -8, 20, -57, 45, 38, 17, 19; /M: SY='F'; M= -48,-102,-115,-110, 68,-115,-103, 57,-107, 21, 6,-108,-111,-107,-107,-102, -90, 48, -92, 18; /M: SY='T'; M= -16, -98, -88, 16, -33, -35, -94, -22, 6, -95, -23, -17, -95, -28, -15, 54, 67, 11,-112, -95; /M: SY='W'; M=-105,-116,-124,-111, 80,-108,-111, -52,-105, -50, -92,-116,-112,-107,-106, -47,-106, -53, 156, 22; /M: SY='T'; M= -48,-100, -94, -95, 51, -56, 59, -92, -91, -90, -9, -42,-100, -91, -25, 35, 74, -90, 18, 52; /M: SY='N'; M= -95,-100, 6, -89, 21, -87, 15, -30, -83, -46, -94, 117,-105, -85, -90, -80, -81, -29,-118, -92; /M: SY='N'; M= -1, 50, 41, -1,-104, -39, 17,-102, 6, -44, -96, 72, -29, -84, -7, -45, 29, -48,-117, -31; /M: SY='T'; M= -44, -95, -87, -45,-102, -16, -94, -48, -88,-100, -95, 2, -93, -34, -95, 73, 86, -43,-115, -97; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='L'; M= -49,-102,-110,-106, -76,-113, -18, 51, -50, 74, -28, -12,-110,-100,-104, -57, -91, -1,-103, -21; /I: I=-28; MI=0; MD=-70; IM=0; DM=-70; /M: SY='P'; M= -34,-112, 13, -24, -52, -97, -96, -46, 3,-109,-100, 10, 98, -4, -95, 29, -37, -31,-113,-105; D=-28; /I: I=-28; DM=-70; /M: SY='T'; M= 10,-103, -49, -24, -8, -68, 2, -52, 30, -5, -32, -41, -43, -44, 19, -7, 53, -32,-101, 41; D=-28; /I: I=-28; MI=0; MD=-70; IM=0; DM=-70; /M: SY='E'; M= -12,-104, 40, 51,-106, -36, 4,-106, 38, -59, -98, 31, -94, -32, -42, 30, 22,-101,-112, -25; /M: SY='P'; M= -26,-108, 24, 11, -97, -17, 1, -97, -14, -44, -94, -41, 55, 9, 22, 3, 19, -9, 37, 31; /M: SY='C'; M= -92, 156,-111,-110,-103,-107,-111,-109,-106,-100,-100, -98, -41, -27,-113, -94, -92, -97,-131,-112; /M: SY='P'; M= -66, -18, 46, -19,-111, -95, -90,-105, -88, -68, -29, 50, 104, -6, -98, -30, -87,-107,-114, -33; /M: SY='N'; M= -32,-104, 4, 18, -38, -55, 40, -4, 18, -95, 7, 43, -52, -4, 34, 9, 14, -22,-105, 26; /M: SY='E'; M= -10,-105, 35, 52,-108, -32, -20, -53, 48,-105, -98, 18, 21, -38, 9, -12, 17, -55,-111, -99; /M: SY='E'; M= 11,-104, 26, 61,-103, -53, 9, -45, 35, -3, -25, -83, -94, 23, -14, -1, 12, -94,-109, -95; /M: SY='I'; M= -94,-104,-112, -32, -14,-117,-106, 88,-105, 41, -66,-107,-107,-102, -48,-103, -89, 21,-100, 0; /M: SY='E'; M= -8, -8, 43, 45,-104, -29, 24, -10, -47, -31, -93, 33, -96, 23, 6, 13, 22, -46,-114, -96; /M: SY='Q'; M= 21,-106, -3, 35,-104, -45, 8,-103, 40, -45, -23, -17, -35, 54, 29, 2, -43, -66,-105, 0; /M: SY='L'; M= -38,-101, -37,-104, -77,-112,-100, 36,-104, 70, 55, -56,-109, -33,-104, -60, -21, 6, 17, -85; /M: SY='R'; M= -30,-105,-100, -56, -7, -39, -92, 30, -9, 26, 22, 3,-105, -10, 41, -11, -11, -16, 34, 38; /M: SY='N'; M= -10,-102, -25, 24,-105, -35, -24,-101, 39, -44, -95, 54, -97, -15, 32, 42, 2, -28,-112, -97; /M: SY='K'; M= -47,-105, -96, -45, -14, -48, -91, 16, 65, -7, 30, -9,-102, -34, 41, -92, -35, 15,-100, 19; /M: SY='M'; M= -59,-101,-115,-108, 43, -62, -97, 32,-106, 65, 88,-108,-110,-100,-104,-104, -93, -70, -96, -29; /M: SY='F'; M= -6,-102, -45, -20, 37, 8, -8, 15, 1, 8, -32, -30,-103, -93, -7, -12, 14, 28,-100, 2; /I: I=-16; MI=0; MD=-40; IM=0; DM=-40; /M: SY='D'; M= -57,-117, 43, -28,-117, -5, 10, -53, 13,-118,-111, 38, -31, -96, -16, 3, 8, -62,-126, -14; D=-16; /I: I=-16; DM=-40; /M: SY='D'; M= -60,-113, 47, 11, -35, -15, -20, -13, -9, -69,-101, 24, 23, 36, -13, -4, -3, -41,-119,-102; D=-16; /I: I=-16; DM=-40; /M: SY='D'; M= -63,-110, 59, 4,-110, 22, -91, -46, 24, -60,-103, 34, 5, -85, 19, 6, -27,-107,-115, -26; D=-16; /I: I=-16; DM=-40; /M: SY='G'; M= -25,-109, 29, 2,-111, 65, 3, -48, -5, -65, -28, 14,-101, -88, 22, 2, -46,-107,-113,-103; D=-16; /I: I=-16; DM=-40; /M: SY='K'; M= -42,-107, -9, -18,-106, 17, -18, -51, 50, -30, -15, 11, -29, 13, 23, 7, 12, -14,-112, -99; D=-16; /I: I=-16; DM=-40; /M: SY='P'; M= -33,-107,-106, -97, -94, -42,-104, 11,-100, 23, -31,-103, 75, 13,-104, -8, -24, 47,-112, -98; D=-16; /I: I=-16; DM=-40; /M: SY='S'; M= -52, -99, -83, -28,-102, -91, -8, -28, 32, -43, -94, 57, -97, -80, 26, 59, 52, -94,-114, -96; /M: SY='Q'; M= 5,-107, 26, 31,-110, -55, -28, -52, 3,-104, -16, 9, 50, 60, -18, 18, 10,-100,-111, -99; /M: SY='E'; M= 33,-103, -14, 52,-107, -35, 20, -66, 15, -70, -95, 22, -95, 15, 11, 26, -17, -24,-111, -97; /M: SY='F'; M= -32, -10,-115,-109, 89,-112,-102, 0,-107, 47, -72,-108,-113,-109,-106, -33, -92, 29, -89, -68; /M: SY='T'; M= -34,-102, 0, -44, -12, -52, -14, 17, 40, -48, -26, -39, -99, 15, -10, 27, 42, 20,-106, -9; /M: SY='R'; M= -12,-105, 31, 19,-106, -32, -22,-102, 32, -30, -95, 39, -98, 30, 42, 18, -1, -39,-112, -97; /I: I=-28; MD=-70; /M: SY='A'; M= 71, -98, -96, -26, -49, -92, -97, -8, 16, -31, -87, -20,-100, 13, -36, -42, 1, 20,-107, -26; D=-28; /I: I=-28; MD=-70; /M: SY='M'; M= -98,-102,-117,-109, 56,-114, -96, -25,-106, 53, 108,-109,-111,-101,-104,-106, -94, -13, -97, -76; D=-28; /I: I=-28; MI=0; MD=-70; IM=0; DM=-70; /M: SY='G'; M= -13,-104, -29, 1, -39, 39, -94, 4, 20, 16, -86, -11, -10, 3, -19, 1, 18, -44,-105, -21; /M: SY='P'; M= -25,-111, -33, -10, -48, -59, -34, -46, 1, -52, -96, 14, 104, -3, -94, 13, -27, -49,-110,-104; /M: SY='E'; M= -46, -18, 54, 71, -33, -12, -86,-106, -13, -39, -14, 8, -15, 15, 4, -25, -37,-103,-109, -11; /M: SY='F'; M=-102,-104,-112,-110, 98,-113, -22, 9,-105, 7, -77, -46,-114,-107,-103,-102, -95, -3, -75, 76; /M: SY='P'; M= -27,-105, -88, -16,-101, -38, 30, -25, 15, -30, -25, 40, 57, -15, 14, 19, 22, -3,-111, -37; /M: SY='V'; M= -42,-102, -37, -50, -86, -18,-109, 52,-104, 10, -15,-104, 14,-103,-107, -97, -36, 76,-111, -92; /M: SY='T'; M= -36,-103, 1, -17, -97, -33, 6, 3, 30, -11, -32, -38, -98, 20, 23, 18, 47, 5,-109, -23; /M: SY='S'; M= -83,-103, 22, -11,-108, 23, -20, -57, 11, -74, -99, 26, -97, 15, 27, 71, -40,-102,-112, -98; /M: SY='V'; M= 10,-100,-109,-105, -18, 9,-108, 37,-103, -4, -21,-102, -33,-103,-106, -49, -41, 75,-108, -20; /M: SY='S'; M= -41,-102, -13, 26, -19, -23, 1, -30, 22, -99, -27, -40, -96, 14, 2, 56, 42, -38, 13, -22; /M: SY='W'; M= -18,-103, -9, -99, 43, -39, -22, -13, -33, 35, 17,-100, 4, -99, -28, -55, -4, 36, 47, 10; /M: SY='Q'; M= -12,-103, -44, 44, -51, -31, -26, 15, 6, -42, -42, 12, -39, 44, -47, 17, 33, -5,-108, -28; /M: SY='P'; M= -22,-107, -99, -39, -9, 26, -96, -19, -46, 3, -88, -94, 60, -11, 21, 4, 3, -6, 44, 18; /M: SY='I'; M= -17,-102, -21, -47, 11,-104, -2, 41, -21, 21, 37, -93,-103, -40, -8, 28, 25, -23,-102, 8; /M: SY='G'; M= -28, 25, -91, 12,-108, 84, -98, -25, -1, -26, -98, 3,-100, -36, -98, -49, -44,-103,-108,-105; /M: SY='S'; M= 8, -7, 16, -11,-102, -56, -19, 8, -13, -21, -25, 34, 33, 22, -93, 37, -7, -7,-113, -98; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 6 in 6 different sequences |
| Number of true positive hits | 6 in 6 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | Peptidase S72 |
| Version [info] | 3 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
6 sequences
DAG1_BOVIN (O18738), DAG1_CANLF (Q9TSZ6), DAG1_HUMAN (Q14118), DAG1_MOUSE (Q62165), DAG1_PIG(Q29243), DAG1_RABIT (Q28685)» more
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