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General rule information [?]

Accession PRU01036
Dates 22-AUG-2014 (Created)
30-SEP-2022 (Last updated, Version 6)
Data class Domain
Predictors PROSITE; PS51699; SEA_DG
Name DG-type SEA domain
Function The DG-type SEA domain forms the peptidase S72 family.

Propagated annotation [?]

Comments [?]

case <FTGroup:1>
Ptm Autolytic cleavage produces the alpha and beta subunits. In cutaneous cells, as well as in certain pathological conditions, shedding of beta-dystroglcan can occur releasing a peptide of about 30 kDa.
end case

Gene Ontology [?]

GO:0016020; Cellular component: membrane.
GO:0016011; Cellular component: dystroglycan complex.

Features [?]

From: PS51699
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Peptidase S72 #        
SITE     53     54       Cleavage; by autolysis     G-S   1

Additional information [?]

Size range 100-120 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q62165 (DAG1_MOUSE)
Eukaryota; Eutheria
Comments None


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Eukaryota [6]