ProRule PRU01036
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU01036 |
| Accession | PRU01036 |
| Dates | 22-AUG-2014 (Created)
30-SEP-2022 (Last updated, Version 6) |
| Data class | Domain; |
| Predictors |
PROSITE; PS51699; SEA_DG |
Name | DG-type SEA domain |
| Function | The DG-type SEA domain forms the peptidase S72 family. |
| Scope(s) |
Eukaryota Eutheria |
| Example(s) | Q62165 (DAG1_MOUSE); |
Propagated annotation
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Comments
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| case <FTGroup:1> | |
| PTM | Autolytic cleavage produces the alpha and beta subunits. In cutaneous cells, as well as in certain pathological conditions, shedding of beta-dystroglcan can occur releasing a peptide of about 30 kDa. |
| end case | |
Gene Ontology
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| GO:0016020; Cellular component:membrane |
| GO:0016011; Cellular component:dystroglycan complex |
Features
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| From: PS51699 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Peptidase S72 #" | |||||||||
| SITE | 53 | 54 | /note="Cleavage; by autolysis" | G-S | 1 | |||||||
Additional information
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| Size range | 100-120 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [6] All [ 6 ]
- Retrieve set of proteins with 3D structure for this domain