ProRule PRU01036

General rule information [?]

Accession PRU01036
Dates 22-AUG-2014 (Created)
30-SEP-2022 (Last updated, Version 6)
Data class Domain;
Predictors PROSITE; PS51699; SEA_DG
Name DG-type SEA domain
Function The DG-type SEA domain forms the peptidase S72 family.
Scope(s) Eukaryota
Example(s) Q62165 (DAG1_MOUSE);

Propagated annotation [?]

Comments [?]

case <FTGroup:1>
PTMAutolytic cleavage produces the alpha and beta subunits. In cutaneous cells, as well as in certain pathological conditions, shedding of beta-dystroglcan can occur releasing a peptide of about 30 kDa.
end case

Gene Ontology [?]

GO:0016020; Cellular component:membrane
GO:0016011; Cellular component:dystroglycan complex

Features [?]

From: PS51699
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Peptidase S72 #"
SITE 53 54 /note="Cleavage; by autolysis" G-S 1

Additional information [?]

Size range 100-120 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

View rule in raw text format (no links)

UniProtKB rule member sequences [?]