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PROSITE entry PS51746


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General information about the entry

Entry name [info] PPM_2
Accession [info] PS51746
Entry type [info] MATRIX
Date [info] 01-FEB-2015 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51746
Associated ProRule [info] PRU01082

Name and characterization of the entry

Description [info] PPM-type phosphatase domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=253;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=248;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.5964444; R2=0.0053016; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=27985.9375000; R2=9.7668266; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=1869; H_SCORE=46240; N_SCORE=11.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=925; H_SCORE=37020; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-41; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='R';  M=  -7,-105,  19, -15, -32,   7, -30, -12,   6,  -2, -89, -35, -18,   8,  38,  25,   3, -26,-106,   0;
/M: SY='Y';  M=   0,  28, -57,-100,  18, -74,  21,  22, -67, -25, -16, -50,-106, -25, -61,  13,   8,  28, -14,  72;
/M: SY='G';  M=   8,  17, -17, -57,-105,  75,  19,-109, -92, -52, -40, -46,-100,  -4, -13,  32, -49,-104,-106,  -3;
/M: SY='M';  M=  12, -39, -61, -35,  28,-103, -26,  13,  -6,  25,  40, -98, -50, -94, -59,  13, -57,  39, -99,  19;
/M: SY='A';  M=  40,  31,  -5,  13,  -9, -49, -16, -54, -35, -38,  -2, -11,  12, -87, -13,  29,  11, -16, -23,  21;
/M: SY='S';  M=  -6,  -7,   8,  33,-104,  -8,  21,-102, -14, -78, -97, -79, -49,  -2, -20,  71,  26, -42,-112, -36;
/M: SY='M';  M=  11,-102,  43, -60, -92, -98, -92,   3,   4,  10,  45,  11,  -1,  -2, -64,  -4,  11,  16,-109,  -8;
/M: SY='Q';  M= -16, -18, -91, -52,-104, -44, -86, -10,   3, -26,  -9,  -5,  22,  87,  50,   8, -49, -57,-105, -31;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='G';  M=  31, -34, -48, -57,-109,  82, -97, -40,   7,-108, -99, -51, -29,  -4, -27, -12, -52,-102,-105, -40;
/M: SY='W';  M=  -2,-107, -15,   8, -19, -46,  -7, -95,  37, -32, -15,   3, -28,   7,  39, -11, -42,  -4,  90,   6;
/I:         I=-24; MI=0; MD=-60; IM=0; DM=-60;
/M: SY='R';  M= -64,-108, -29, -50,-107,   5,  10,-109,  26, -57, -29,  15,   0, -17,  82,  26, -29,-105,-110, -96; D=-24;
/I:         I=-24; DM=-60;
/M: SY='H';  M=   1,  -6,  28,  24,-103, -30,  34, -40,  10, -16, -34,  17,  13,   1,  28,  11, -12, -28,-113, -95;
/M: SY='H';  M=  14,  19, -48,  30, -37, -23,  47, -27,   3, -50,  -8,   4,  32, -85, -61,  13,  31, -15,-109,  -5;
/I:         I=-10; MD=-24;
/M: SY='M';  M= -60, -26, -30, -36, -97,  30, -87, -37, -89, -24,  97,  61, -23,  26, -25,   3, -87, -26,-111, -94; D=-10;
/I:         I=-10; MD=-24;
/M: SY='E';  M= -57,  22,   0,  95,-114,   7, -87, -58, -40,-107,-101, -44, -46,  47, -85, -34, -48,-106,-111,-103; D=-10;
/I:         I=-10; MD=-24;
/M: SY='D';  M= -98,-111, 118, -66,-115, -97, -87, -49, -88, -49,-109, -69, -99, -87, -96, -31, -47, -42,-132,-101; D=-10;
/I:         I=-10; MD=-24;
/M: SY='A';  M=  47, -24, -32, -61,  14, -71,   6, -54, -52, -61, -91,  -9,-102,   1,  47,  27,  -8,   4,  -1,  -5; D=-10;
/I:         I=-10; MD=-24;
/M: SY='H';  M=  -1,  24, -14, -34,  31, -66,  80, -30, -96, -40,   5, -94,-107, -27, -40, -24, -92,  28,  47,  63; D=-10;
/I:         I=-10; MD=-24;
/M: SY='F';  M= -19,   5, -10,  -8,  47,   4,  29,  -1, -97,  18, -82, -18,-105,   6, -99,   4,  -9,  17,-101, -11; D=-10;
/I:         I=-10; MD=-24;
/M: SY='V';  M=  13,  37,-106,-102,  -6,-105, -44,  31, -36, -31,  35, -45,-106, -14,-101, -18,  22,  53,-107,  10; D=-10;
/I:         I=-10; MD=-24;
/M: SY='V';  M=  -1, -19,-108, -18,  18, -69,-104,  26,   5,   5, -24, -25,-111, -21, -19, -99, -32,  30,  27,  10; D=-10;
/I:         I=-10; MD=-24;
/M: SY='P';  M= -80, -16, -13,   1, -62,-117, -36, -35, -70,   7, -27,  -7,  30, -20, -13, -23,  -3,   5,  -9,   1; D=-10;
/I:         I=-10; MD=-24;
/M: SY='N';  M= -43, -15,  40, -24,-128, -20, -43,-125,-103, -81, -31,  57,  -9,-105,  -6, -38, -23, -75,-140,-121; D=-10;
/I:         I=-10; MD=-24;
/M: SY='F';  M= -46,-129,-129,-129,  44, -42, -53, -33,-125,  23, -20,   6, -40, -46, -58, -71,-118,-108,-120, -46; D=-10;
/I:         I=-10; MI=0; MD=-24; IM=0; DM=-24;
/M: SY='S';  M= -29, -13, -40, -74,  -7, -16,-109, -44, -59,-119,-114,  18,  12,   2,   2,  28, -57, -56,-123,  -3; D=-10;
/I:         I=-10; DM=-24;
/M: SY='N';  M= -10, -39, -10,  14, -36,  23,-100, -28,  14, -17,-102,  28, -42, -23,  -9,  14, -96, -74,-118,-106; D=-10;
/I:         I=-10; DM=-24;
/M: SY='D';  M= -50, -11,  38,  28, -53,  11,  35, -43,   4, -45, -47,  -3, -38,  -3,  19, -31,  16, -37,-112,   1; D=-10;
/I:         I=-10; DM=-24;
/M: SY='D';  M= -20,-107,  42,  24, -30, -11, -33, -68, -14, -15, -95,  25,  37,  15,  -7,   6,   3, -14,-113, -98; D=-10;
/I:         I=-10; DM=-24;
/M: SY='D';  M= -35,-106,  52,   8, -50,   9,  22,-107,  -2, -62,-100,  42,  21,   1,   5,  27, -12, -52,-115, -98; D=-10;
/I:         I=-10; DM=-24;
/M: SY='W';  M=   8,  -2, -22,  20,  11,  -6, -31,  20, -51, -35, -88, -47, -32,   2, -16,  -5,  -3,   8,  83,   7; D=-10;
/I:         I=-10; DM=-24;
/M: SY='H';  M=  15,  16,   9, -29, -25,  21,  36,  -5, -94,  11, -12,  -4, -49, -45, -60,  23,   3, -48,  -4,  21; D=-10;
/I:         I=-10; DM=-24;
/M: SY='F';  M= -17,-102,-111,-107,  72, -60, -34,   7,-105,  41,   6, -22,-111,-104,-104, -99, -25,  22,  16,  33; D=-10;
/I:         I=-10; DM=-24;
/M: SY='F';  M= -11,  46,-113,-109,  86,-109, -99,  18,-105, -18,  18, -47,-112,-107,-105, -57, -93,  20,  48,  42; D=-10;
/I:         I=-10; DM=-24;
/M: SY='G';  M=  57,  17, -99,-102,-106,  77,-103,  -4, -99, -68, -95, -88,-100, -97,-105, -48, -91, -12,-107,-104; D=-10;
/I:         I=-10; DM=-24;
/M: SY='V';  M= -88,-100,-115,-109, -32, -68,-112,  48,-107,  10,  16,-109,-109,-107,-108,-100, -85,  88,-112, -89; D=-10;
/I:         I=-10; DM=-24;
/M: SY='F';  M=  32,  43,-108,-106,  89, -36, -91, -42,-102, -32, -84,-101,-111,-103,-102, -33, -93, -87, -78,  76; D=-10;
/I:         I=-10; DM=-24;
/M: SY='D';  M= -99,-112, 121, -33,-119, -95, -84,-117, -85,-116,-114, -14, -98, -85, -50, -87, -88,-114,-134,-102; D=-10;
/I:         I=-10; DM=-24;
/M: SY='G';  M= -33,-106, -96,-105,-111, 102,-102,-111, -99,-111,-102, -82, -99, -97, -55, -46, -96, -11,-105,-107;
/M: SY='H';  M= -95, -15, -24, -90,  -1, -36, 126, -52, -34, -14,  40, -83,-103, -85, -10, -93, -94,  25,-116, -30;
/M: SY='G';  M= -10,-104, -20, -30,-110,  87, -30, -58, -63,-110,-101,  29, -99, -91, -19,   6, -49, -42,-108,-104;
/I:         I=-28; MI=0; MD=-70; IM=0; DM=-70;
/M: SY='G';  M= -53,-106, -93,-105,-113, 104, -99,-120, -98,-116,-105,   8, -99, -96,-106, -39, -96,-113,-105,-108;
/M: SY='H';  M=   9, -38,   0, -62, -97, -43,  56,  12,  12, -94, -89, -17,  34, -52,  22,  21, -13,  14,  50, -15;
/M: SY='E';  M=  17,-105,  36,  48, -19,   9,   4,-103,   6, -39, -15,  -1, -43,  27,  14,  -6, -42, -52,-109, -95;
/M: SY='A';  M=  70,  50,-100, -36, -46, -41,-103,   4, -57, -60, -86, -44, -46, -94, -24, -21, -20,  43,-110, -97;
/M: SY='A';  M=  68, -11, -94, -51,-105,  27, -33, -97, -55, -65, -94, -42,  -3, -88, -50,  52, -10, -21,-109,-100;
/I:         I=-2; MD=-4;
/M: SY='K';  M= -12,-107,  36,  40,-103, -44, -23, -44,  41,  -8,  14,  -1, -98,  41,  23, -52, -43, -33,-109, -37; D=-2;
/I:         I=-2; MD=-4;
/M: SY='F';  M= -21, -25,-109,-105,  85,-109, -38,   0, -61, -10,  24,-103,-111, -32,  -9, -26, -94,  -8,   8,  71; D=-2;
/I:         I=-2; MD=-4;
/M: SY='C';  M=  48,  55, -31, -27, -91, -72,-100, -22, -98,  23,  45, -47,-104, -95,-101,   0,  -7,  35,-111, -95; D=-2;
/I:         I=-2; MD=-4;
/M: SY='S';  M=  38,   5, -94, -45,-103, -20, -40, -60,   6,-100,  25, -86, -23,  20,  49,  52, -37, -66,-107, -14; D=-2;
/I:         I=-2; MD=-4;
/M: SY='E';  M= -17,  -7,  34,  44,-111, -31,  -9,-108,  34,-107,  -5,  15, -12,  25, -20,  25,  -5, -73,-115,-101; D=-2;
/I:         I=-2; MD=-4;
/M: SY='H';  M= -44,-107, -53, -24, -51, -69,  81,   4, -20,  29,  21,  36,-107, -88,  29, -62,  -6, -48,-111,  -3; D=-2;
/I:         I=-2; MD=-4;
/M: SY='L';  M= -46,-104,-117,-109,  21,-117, -21, -16, -58,  68,  66,-112,-115,-103, -60,-107, -55,   2,-103, -34; D=-2;
/I:         I=-2; MD=-4;
/M: SY='H';  M= -41,  -7, -51, -99,  16, -37,  72, -64,-100, -37, -94, -23,  51, -52, -53,  17, -22,   7,  19,  31; D=-2;
/I:         I=-2; MD=-4;
/M: SY='R';  M= -47, -39, -13,   5, -41, -53, -15,-113,  14, -49,-107,  23, -20, -53,  34,  12,   0, -41,-122, -28; D=-2;
/I:         I=-2; MD=-4;
/M: SY='Y';  M= -10,  -2, -61, -18,  -6,-130,  21, -28, -75, -26, -51, -25,-133,-119, -65, -33, -64, -42,  -5,  26; D=-2;
/I:         I=-2; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='C';  M= -11,  37, -36, -27, -30, -41,-118, -43, -42, -13,-111, -62,  23, -31, -48,  18, -37, -78, -20,-117; D=-2;
/I:         I=-2; DM=-4;
/M: SY='Q';  M= -18,-122,  -2,   8, -27, -83, -28, -12, -33,   1,-102, -39,-117,  30,  -3,  17,-104, -75,  20,-106; D=-2;
/I:         I=-2; DM=-4;
/M: SY='W';  M= -40, -14, -45,  -4,  16, -35,  -8, -38,   8, -12, -43, -12,   5, -20,  -7, -24, -29, -55,  16,  -1; D=-2;
/I:         I=-2; DM=-4;
/M: SY='Y';  M= -29, -44,  -3,  16,  -7, -20,  -8, -38,  -4,   1,  12,   0, -27, -24, -21, -16, -55, -38, -10,  25; D=-2;
/I:         I=-2; DM=-4;
/M: SY='H';  M= -10,-115, -62,  22, -65, -24,  22,   0,  -8,   3, -34, -52, -55,  19, -23, -12, -14,  -2,-118, -54; D=-2;
/I:         I=-2; DM=-4;
/M: SY='Q';  M= -39, -15,  -5,   9, -33, -41,-101, -23,  19,  12, -36,  17, -32,  20, -14,   1, -55, -50,  18,-102; D=-2;
/I:         I=-2; DM=-4;
/M: SY='E';  M= -12,-113,  20,  29,   2, -69,-100, -70,   8, -37,-102,  22, -63,   3, -39,   7, -10,   4,-119,-102; D=-2;
/I:         I=-2; DM=-4;
/M: SY='E';  M=  -7,   7,  18,  23, -35,  14,  11, -62,  -2, -66, -30, -34, -20,  18,  -3,  -5, -39, -48,-118, -39; D=-2;
/I:         I=-2; DM=-4;
/M: SY='D';  M=  -8,   0,  26,  -2, -55,   9,-101, -32, -22, -24,  -3, -20,   8, -28,  -2,  15,   5, -33,-119,-105; D=-2;
/I:         I=-2; DM=-4;
/M: SY='E';  M= -15,  -1,  21,  39,  15, -35, -25, -96,  -5,   0, -94, -57, -18,   1, -61,  -4,  21, -11,-110, -25; D=-2;
/I:         I=-2; DM=-4;
/M: SY='P';  M= -30,   0,  14,  19,  14, -77, -10, -94,   7,  -3,  15, -34,  22,   1, -40,  -8,  16,  -8,   8, -44; D=-2;
/I:         I=-2; DM=-4;
/M: SY='P';  M= -35,-109,  21,  25, -36,   1,   5, -10,   4,   1,  -8, -14,  32, -18,  -2,   1, -16, -28,-110, -19; D=-2;
/I:         I=-2; DM=-4;
/M: SY='E';  M=   0,-105,  12,  44,-100, -10,  12, -65,   2, -19, -93, -24, -45, -12,  20,  35,  -9, -15,  -4,  -3;
/M: SY='D';  M=  13,-104,  47,   6, -39,  -5, -28, -49,  -9,  13, -41,  42, -25,   2, -64,   2, -25, -29,  -8, -38;
/M: SY='W';  M=  -9, -27, -35, -23, -20, -64,-105,  24,-100,  16,  12,-103,  38, -51,-104, -26, -16,  50,  71, -29;
/M: SY='R';  M= -48,   0, -18,  48,-104, -19, -29, -60,  34, -20, -39, -54, -12, -47,  48,  15,   3,  -6,-111, -98;
/M: SY='E';  M=  -4,-107,  38,  43,-111,   7, -87,-108,  26,-106,   5,  26, -44,  33,  22, -14,   3,-103,-112,-100;
/M: SY='A';  M=  62,   7, -12, -53, -48, -21,-101,  15, -63, -17, -86, -94,-102, -17, -55, -11,   0,  23,  37,  -8;
/M: SY='L';  M= -61,  25, -45,-106,  18,-114,  14,  48,-105,  62,  58,-106,-111, -27,-105,-104, -93, -35,-102, -38;
/M: SY='R';  M=  -6,-106, -39,  25, -24, -20,  -2,  -3,  16,  -9, -38, -21,  -5, -82,  51,  19,  -9, -16,-107, -40;
/M: SY='R';  M=   0,-106,  23,  14, -41, -52, -86,-106,  39, -79, -97,  23, -17,  26,  44,  24, -24,-102,-105,  17;
/M: SY='A';  M=  60,   5, -40,  -6,-104,  23, -35, -16, -93, -73, -31, -87, -54, -23, -98,  32,  34, -24,-111,-100;
/I:         I=-26; MD=-67;
/M: SY='F';  M=-101,  -8,-109, -20,  99,-113, -96,   0, -21,   9, -80, -61,-113, -41, -55, -58, -42, -18, -82,  36; D=-26;
/I:         I=-26; MD=-67;
/M: SY='L';  M=   2, -15, -18,  20,  -2, -40,   7, -21, -13,  38, -16, -14,-104,  25,   5, -44, -19,  -4,  -8, -36; D=-26;
/I:         I=-26; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='R';  M=  16,-106,   7,  26,-105, -98, -20,-100,   7, -15,  -9,  14, -44,  36,  54,   8, -19, -38,-111, -97; D=-26;
/I:         I=-26; DM=-67;
/M: SY='M';  M=   3,  31, -50, -59, -87, -71, -30,  10, -98,  21,  63, -95,-103, -46,-101, -19,  54,  34,-110, -17;
/M: SY='D';  M= -97,-111,  98,  30,-113, -96,  16,-114, -24,-112,-106,  47, -98,  23, -30, -86, -89,-112,  -4, -39;
/M: SY='E';  M= -34, -13,  16,  57,-106, -59, -26,-105,  25, -29, -32,  16, -26,  32,  40,   8, -42, -71,-110, -29;
/I:         I=-5; MD=-14;
/M: SY='E';  M=  14, -30,  20,  48, -50, -44,  10, -69,  31, -26,  17, -50,-100,  25,   0, -37, -27, -19,-113, -98; D=-5;
/I:         I=-5; MD=-14;
/M: SY='M';  M= -74,  11,-118, -73,  52,-118,-103,  39, -64,  37,  59,-111,-115,-107,-108,-107, -52,   7, -17,  19; D=-5;
/I:         I=-5; MD=-14;
/M: SY='L';  M=   8,-107,-102, -25, -53,   9,  -1, -63,   4,  23,  10, -17,-108,   1, -12,   0, -18,   7,  -9,  -3; D=-5;
/I:         I=-5; MD=-14;
/M: SY='D';  M= -22,-111,  25,  24,-109, -39, -28, -38,  21, -11, -35,  -9,-104,  19,  13,  17,   7, -35,-118,-102; D=-5;
/I:         I=-5; MD=-14;
/M: SY='H';  M= -21,-115, -60,  42,-106, -51,  44, -57,  13, -14,  31,  -4,-107,  20, -34, -12, -47, -17,  17, -43; D=-5;
/I:         I=-5; MD=-14;
/M: SY='R';  M=  -2,  -9, -21, -77, -11, -12, -32, -24, -31,  -4,-103, -57,-125,-112,   7, -49, -42,   5,-124, -19; D=-5;
/I:         I=-5; MI=0; MD=-14; IM=0; DM=-14;
/M: SY='A';  M=  39,-122,-115, -17,-129, -57, -40, -70,-115, -76, -20, -50, -20,-110,-120,  36, -18,-114,-135,-124; D=-5;
/I:         I=-5; DM=-14;
/M: SY='N';  M=-107,   4,   3,  12,-117,-112, -30,-111, -36, -22,-110,  53,-117,  -7,-107,  10,  -5, -15,  25,-112; D=-5;
/I:         I=-5; DM=-14;
/M: SY='P';  M= -28,-119, -44,  33, -12, -51,-104, -18, -13,-109,  -1, -58,  57, -28,   7,  10,  -9, -46,-118,-107; D=-5;
/I:         I=-5; MI=0; MD=-14; IM=0; DM=-14;
/M: SY='D';  M= -40,-121,  37,  24,-119,   3,  28,-117, -97, -43,-110,  -3, -12,   9,  -4, -25,  -4, -49,-127, -48; D=-5;
/I:         I=-5; DM=-14;
/M: SY='C';  M= -58,  47,  19,   9,  -4,   3,-105, -99, -31,   7, -47, -34,  33,-100, -44, -14, -20, -11,-118, -56; D=-5;
/I:         I=-5; DM=-14;
/M: SY='W';  M=  39,-107, -12,  22, -33, -11, -99, -18, -42,  -4, -17, -48, -60,  21, -21,   2, -42, -10,  53, -48; D=-5;
/I:         I=-5; DM=-14;
/M: SY='R';  M= -16,  17,   1,   1, -15, -13, -40, -34,   4,  -9,  -9, -18, -56,  -7,  21,  18,  16, -13,  -8,  11; D=-5;
/I:         I=-5; DM=-14;
/M: SY='M';  M= -28,   2, -19,  -9,-101,  48, -20, -32, -52, -41,  63, -85, -30, -89, -98,  59, -12, -15,-111, -98; D=-5;
/I:         I=-5; DM=-14;
/M: SY='G';  M= -29,-106, -48,-103, -20,  94, -99,-115, -98,-112,-103, -82,-100, -95, -45,  21, -27,-109,-103, -10;
/M: SY='C';  M=  32,  80, -47, -93,-103, -56, -98, -56, -93, -66, -96, -83, -99, -90, -99,  74,  52, -54,-116,-101;
/M: SY='T';  M= -38,  66, -92, -94,-100, -98,-100, -92, -91, -96, -26, -81, -35, -94, -99,  17, 106, -39,-120, -99;
/M: SY='A';  M=  84,  24,-103, -97, -98, -17,-102, -18, -98,  -3,   0, -96,-102, -94,-101, -21, -85,   3,  -3, -98;
/M: SY='C';  M= -21,  68, -50, -60, -17,-108,-105,  17, -49,  25, -12, -59,-107,-101,-104, -15,  37,  54,-112, -92;
/M: SY='V';  M=  -9,  34,-110,-106,  -7, -77,-107,  28,-104,  17, -33,-103,-108,-104,-106, -65,  28,  70,-108,  -9;
/M: SY='A';  M=  61,  42,-104, -99, -48,  -4,-104, -10, -98, -13,   8, -96,-103, -97, -45,  -3,  -6,  43,-111, -97;
/M: SY='L';  M= -28, -33,-106, -50, -53,-110,  42,  43, -57,  45,  -4, -45, -38, -97, -41, -13, -36,  33, -11,  14;
/M: SY='I';  M= -48,-103,-113,-107,  26,-114,-102,  58, -48,  44,  36,-107, -46,-102, -45, -56, -60,  36, -99,  10;
/I:         I=-11; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='Q';  M= -10, -45,  18, -30, -43,   1,  13, -42,  29, -22, -31,   4,-100,  32,  16,  21,   5,   8,-108, -20;
/M: SY='G';  M= -88,-108,  54,   5,-111,  56, -41,-111,  14, -42,-101,  33, -16,  20,  -1,  -1, -50,-108,-112,-101;
/M: SY='N';  M= -24,  -9,  24,   4, -49,  26,  15, -50,  21, -51, -32,  44, -99,  28,  21,   0, -22, -69, -13,  -7;
/M: SY='K';  M= -52,-105,  26,   3, -38, -67,  32, -25,  50, -77, -92,  13, -97,  26,  17,  -6,  37,  -4,-110, -21;
/M: SY='L';  M= -42, -23,-113, -60,  -6,-115,-103,  31,-107,  75,  -4,-110,-111,-102,-106, -66, -61,  29,-103, -85;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='Y';  M= -27, -24, -44, -28,  16, -71,  60,  12, -12, -56, -37, -92,-105,  30, -23, -29,   0,   2,  17,  85;
/M: SY='V';  M= -26,  -9,-108,-105, -27,-109,-104,  40,-102, -28, -15,-102,-106,-102,-104,  -4,  14,  76,  -4,  38;
/M: SY='A';  M=  89,  27,-102, -95, -27, -15,-101, -11, -96, -27,  14, -95,-100, -93,-100, -58, -46, -35,-106, -98;
/M: SY='N';  M= -91,  14, -73, -89,-102, -85,  41,-105, -47,-109, -98, 113,-103, -35, -88,  23, -43, -68,  46, -18;
/M: SY='V';  M=  35,  19,-108,-103, -87,-105,-107,  40,-101,  23, -74,-102,-105,-101, -52, -90,  20,  61,-111, -93;
/M: SY='G';  M= -80,-108, -95,-107,-114, 107,-102,-122,-101,-117,-106, -81, -99, -98,-108, -80, -99,-115,-105,-109;
/M: SY='D';  M= -97,-110, 116, -66,-116, -35,  33,-115, -50,-113,-110, -17, -98, -85, -93, -49,  -7,-112,-131, -98;
/M: SY='S';  M= -14,  47, -89, -26,-103, -85, -27, -99, -90, -62, -16, -38, -16, -83, -94,  98, -11, -28,-114, -98;
/M: SY='R';  M= -32, -38, -40, -59,-106,  12, -88,-108, -10, -49,  -1, -87,  25,   7,  97, -31, -56,-104, -10, -96;
/M: SY='A';  M=  76,  52,-103, -98,  32,   3,-102, -12, -98, -64, -88, -95, -44, -97,-102, -35, -33,   7,-103, -47;
/M: SY='V';  M= -26,-101,-112,-107,  17, -49,-102,  35, -60,  16,  19,-106,-109,-103,-104, -98, -54,  73, -99,  40;
/M: SY='L';  M= -37,-101,-115,-108, -75,-115,-103,  31,-107,  75,   4,-112,-112,-103,-106,-104, -91,  38,   4, -34;
/M: SY='C';  M=  15,  95, -58,-101,  -3,   6,  -4,   8, -54,  -1, -30, -93,-107, -34,-102,  31, -86,  10,-107,   3;
/M: SY='R';  M= -91,-107,   8, -49, -52, -66,  -7, -39,   9, -70, -93, -14,-101,  25,  86,  23,  18, -27,-109, -43;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='N';  M= -24,-105,  64,  -7,-111,   8, -84,-111,  19,-111,-102,  73, -99,   8,  21,   6, -49,-107,-117,-100;
/M: SY='G';  M= -32,-106,   9, -65, -63,  88, -31, -65, -40, -76,-102,  27, -99, -27, -65,  -3, -42, -72,-107, -40;
/M: SY='Q';  M= -47,-106,  10,  41, -62, -21,  29, -22,  29, -46, -18,  14, -96,  43,  11,   4,  21, -23,-111, -94;
/I:         I=-7; MI=0; MD=-18; IM=0; DM=-18;
/M: SY='A';  M=  62,  -6, -51, -95,  22, -61,-100,  -9, -23, -23, -85, -58,  21,  -8, -98, -19, -52,  36,-102,   0;
/M: SY='H';  M= -70,-103,-101, -20,  -6,-110,  47,  37,   8,  22,  17, -96,-105, -30,   2, -39,  -1,  43,-104,   7;
/M: SY='Q';  M= -12, -30,   4,  16,  -3, -99,   9, -46, -13, -21, -31, -31,  37,  80,   9, -16,   8, -42,-107, -92;
/M: SY='L';  M= -61, -28,-111,-103, -27,-113, -97,  -4, -65,  78,  46, -51, -46, -45,   4, -48, -92,  -8,-103, -85;
/M: SY='T';  M= -79, -23, -86, -50,-103, -89, -20, -98, -44,-102, -42,  12,  -9, -35, -93,  79,  82, -91,-116, -97;
/M: SY='K';  M= -18,-103,  -9,  20,   0, -34,  -8, -19,  37, -93,  -6,  -6, -99,   6,  15,  18,  12,  25,-105,  -2;
/M: SY='D';  M= -23,-109,  95,  32, -56, -63, -87, -59,  -3, -70, -26, -75,  10,  -3, -38, -10,  -7,-104,-118, -48;
/M: SY='H';  M= -97,-110, -24, -84,  -7, -13, 134,-108, -88, -46, -10, -36,-102,  45, -85, -29, -96,-109,-115,  10;
/M: SY='K';  M= -90,-104, -15,  -8, -51, -98,  45, -97,  51, -24, -91,  23,   1,   1,  12,  11,  47, -24,  -5, -15;
/I:         I=-3; MI=0; MD=-8; IM=0; DM=-8;
/M: SY='P';  M=  -6,-137,-123, -67,-135,-124,-126, -63,-119,-129, -32, -53,  81,-121, -70, -73,   3, -44,-138,-133; D=-3;
/I:         I=-3; DM=-8;
/M: SY='N';  M= -37,-128,  21,  -5, -32, -84, -38, -36,-111, -90, -50,  28, -52, -28, -60,  15, -20, -70,-135, -23; D=-3;
/I:         I=-3; DM=-8;
/M: SY='N';  M= -78,  -8,  34, -56, -67,-120, -11, -37,-104, -40,-114,  34,   1, -22,  18, -29,-109, -31,-135, -28; D=-3;
/I:         I=-3; DM=-8;
/M: SY='E';  M=-115,-133,   3,  49,-126,-125,-112, -37, -45, -43,-117,-111,  46, -54, -15, -35, -27,-120,-131, -30; D=-3;
/I:         I=-3; DM=-8;
/M: SY='D';  M= -28,-128,  46,  24,-131, -49,-110,-125, -22, -72,-121, -49, -63, -14,   0,  -7, -26, -42,-137,-121; D=-3;
/I:         I=-3; DM=-8;
/M: SY='E';  M=-113,-134, -85,  93,-135,-129,-107, -66, -95,-128,-125,-110,-109, -88,-105, -61,-113,-127,-133,-126; D=-3;
/I:         I=-3; DM=-8;
/M: SY='R';  M= -16, -35,-120,-110,-117,-127,-112, -15,   5, -44, -25,-113,-126,-102,  66, -67, -47, -29,-125,  -8; D=-3;
/I:         I=-3; DM=-8;
/M: SY='E';  M= -23,-129, -43,  32, -53,-120,  -8, -51, -11, -64, -48, -24,-119,  32,   4,   3, -66,-120,  20,-114; D=-3;
/I:         I=-3; DM=-8;
/M: SY='R';  M= -62,-135,-115, -35,-129,-129,-106,-134, -78,-127, -47,-110,-127, -93,  96,-114,-118,-128,-129,-116; D=-3;
/I:         I=-3; DM=-8;
/M: SY='I';  M=-116,-128,-139,-135, -52,-142,-136,  77,-131, -13, -89,-130,-129,-129,-134,-126,-111,  14,-128,-109; D=-3;
/I:         I=-3; DM=-8;
/M: SY='E';  M=-114, -47,-102,  41,-128,-125,  -1, -56,  26, -51,-114, -54,-118,  28,  16, -36, -45, -49,-131,-117; D=-3;
/I:         I=-3; DM=-8;
/M: SY='Q';  M=   9,-126,  10,  -9, -62, -53,   2, -64, -17, -64, -49,  10,-120,  20,  -4,  -7, -54,-119,-133,-117; D=-3;
/I:         I=-3; DM=-8;
/M: SY='C';  M=  38,  39, -33,  -6,-122,-113, -30,-116, -73,  -5,-111, -30, -52, -54,-118,  10, -71,-111,-134,-120; D=-3;
/I:         I=-3; DM=-8;
/M: SY='G';  M= -35, -25, -64, -60,-130,  68,  57,-137, -21,-131,-120,-100, -25,-110,-116,-102,-116,-131,-129,-117; D=-3;
/I:         I=-3; DM=-8;
/M: SY='G';  M= -16,-123,-113, -62, -22,  72, -38, -51,-116, -43,-114,-103,   3,-114,-122, -39,-112,-119,-121,-117; D=-3;
/I:         I=-3; DM=-8;
/M: SY='F';  M= -69,-118,  20, -25,  51,-115,   0, -57, -48, -18, -45, -60, -28, -26,  31, -25, -15, -45,  45,  17; D=-3;
/I:         I=-3; DM=-8;
/M: SY='V';  M= -38,-108,  16,-105, -57,-115,-109,  31, -65,  -7, -83,   9,-114, -49,-109, -66, -92,  71,-117,  -5; D=-3;
/I:         I=-3; MI=0; MD=-8; IM=0; DM=-8;
/M: SY='M';  M=-100,-112,-109,  -9,  52,-111,-103, -69,-100,  -7,  63,-102,-113,-100,  14,  45,  -2, -66,-109, -89; D=-3;
/I:         I=-3; MI=0; MD=-8; IM=0; DM=-8;
/M: SY='N';  M=-107,-120,  71,   2,-128, -35, -93,-125, -94,-126,-118,  75,-112,  31,-101, -94, -98,-125,-137,-115; D=-3;
/I:         I=-3; MI=0; MD=-8; IM=0; DM=-8;
/M: SY='W';  M=-100,-121, -24,-108,-109,  64,  55,-125,-105,-121,-112,  38,-113, -47,-110, -96,-108,-126, 104, -96; D=-3;
/I:         I=-3; MI=0; MD=-8; IM=0; DM=-8;
/M: SY='R';  M=-109,-125,-105, -93,-111,-118, -30,-122,   9,-115,-105, -98,-117, -83, 102,-103,-107,-117,-112,  14; D=-3;
/I:         I=-3; MI=0; MD=-8; IM=0; DM=-8;
/M: SY='V';  M=-108,-120,-132,-126, -12,-133,-129,  29,-124,   0, -33,-126, -40, -52,-126, -47,-104,  61,-127,-106; D=-3;
/I:         I=-3; DM=-8;
/M: SY='N';  M=-111,  22,   0, -32, -12, -41,-101, -75,  13,  -3,-107,  74,-121,  -7,-102,-102,-103,-115,-129,-111; D=-3;
/I:         I=-3; DM=-8;
/M: SY='G';  M= -55,-123, -22,-117, -59,  79,-115, -50,-114,-128,-119,  -1,-116, -29,-121, -97, -56,-125,-123,-121; D=-3;
/I:         I=-3; DM=-8;
/M: SY='V';  M= -98,  -8, -62, -42,-105, -26,-107,  14,-100, -44,  31,   1, -26,  34,  -6,   8, -38,  41, -13,-104; D=-3;
/I:         I=-3; MI=0; MD=-8; IM=0; DM=-8;
/M: SY='L';  M=-114,-118,-132,-125, -23,-133,-119,  10,-125,  67, -80,-128,-130,-120,-124, -63, -35, -39,-120,-101; D=-3;
/I:         I=-3; DM=-8;
/M: SY='A';  M=  57, -36, -51,  -4,-121, -27, -33, -72,  -5,-113,   4,  19,-111,  17,-102, -51, -34,-106,-123,-113; D=-3;
/I:         I=-3; DM=-8;
/M: SY='V';  M=-100,-112,-119,-115, -52,-121,-116, -33,-114,  17,  30, -26,  -5,-113,-116, -17,   6,  62,-125,-103; D=-3;
/I:         I=-3; DM=-8;
/M: SY='S';  M= -14, -38,-100,-102, -62, -99,-106,-109,-101, -76,-107, -90,-105, -97,-106,  76,  65,-101,-126,-108; D=-3;
/I:         I=-3; DM=-8;
/M: SY='R';  M= -67,-125,-104, -54,-118,-118, -95, -65, -42,-116,-105, -48,-116, -18, 106,-102,-107,-116,-118,-105; D=-3;
/I:         I=-3; DM=-8;
/M: SY='A';  M=  73,-102,-102, -98,-112,  -8,-104, -40, -98,-106, -32, -95, -17, -28, -52,  41, -19, -67,-115,-107; D=-3;
/I:         I=-3; DM=-8;
/M: SY='F';  M= -98, -29, -53, -66,  72,-115,-103,  62, -67,  42, -71,-106, -48, -42, -34, -40, -92,  -8, -93, -74;
/M: SY='G';  M= -58, -10, -51,-103,-111, 100,-100,-118, -99,-115,-105, -81, -45, -31,-105,   2, -59,-112,-105, -40;
/M: SY='D';  M= -28,-109, 100, -26, -27, -68, -13, -56,  -6,-102,   6, -45, -21,  -2, -46, -34, -49, -14,-115,   9;
/M: SY='H';  M=  -6,-105,  17,   0,  45,   0,  49, -36,   0,  -6,  28, -90, -46, -90,   8, -58,  -9,   2, -19,  19;
/M: SY='Y';  M= -27,  16,  19,  24,  19, -24,  16,-102, -22, -78, -94,   8,  25,  47,  -6,  -8,  -3,-101,  -7,  53;
/I:         I=-10; MD=-24;
/M: SY='Y';  M= -65,-106, -14, -53,  16,  -4, -93,   0, -25,  47,   9,  -3, -27,  -7, -99, -29, -40, -21, -95,  55; D=-10;
/I:         I=-10; MD=-24;
/M: SY='K';  M=-104,-116, -62, -24,  14, -72,   4,-110,  85, -20,-100, -24,-107, -86,   2, -99, -49,-109,-110, -42; D=-10;
/I:         I=-10; MD=-24;
/M: SY='W';  M= -80, -48, -14,   3,-126, -83, -38, -70,   8, -78,-119, -15, -49,   7,   4,   5, -32, -37,  30, -41; D=-10;
/I:         I=-10; MI=0; MD=-24; IM=0; DM=-24;
/M: SY='P';  M= -73, -15, -35,-102, -21, -81,  -6, -49, -27, -79,-112, -64,  77,  41,-111, -20,-108,-120,-121,   4; D=-10;
/I:         I=-10; DM=-24;
/M: SY='Y';  M= -29,-121,-117,-115,   0,  27,   4, -33, -61, -20,  33,-109,  -4, -50, -59, -29,-107, -17,   4,  52; D=-10;
/I:         I=-10; DM=-24;
/M: SY='V';  M=-104, -45,-127, -62, -50,-130,-124,  36,-119,  19,  -7,-123,-123,-118, -58,-115,-101,  63,-124,-103; D=-10;
/I:         I=-10; DM=-24;
/M: SY='S';  M= -72,-112,-107,-108,-106,-110, -29,  38,-106, -44, -19,   9,-112, -18,-111,  49,  37,   1,-126,-106; D=-10;
/I:         I=-10; DM=-24;
/M: SY='C';  M=  51,  54, -53,-104,-117, -40, -26, -60,-106,-113,-107, -50,  40,-104,-112,  27, -32, -36, -25,-114; D=-10;
/I:         I=-10; DM=-24;
/M: SY='E';  M= -19,-113,  30,  64, -59, -65, -45, -61, -93, -32,-102, -95, -51, -89, -33,  -9,  21,  10,-123,-107; D=-10;
/I:         I=-10; DM=-24;
/M: SY='P';  M= -25,-124,-104, -93,-119, -64, -16,-106, -99, -74,-104,-108, 118,-102, -35, -99, -96, -29,-116,-116; D=-10;
/I:         I=-10; DM=-24;
/M: SY='E';  M= -59, -33,  62,  68, -25, -99,  16, -57, -31, -42, -29, -32, -42,  17, -88,  20, -32, -43,-109,  15;
/M: SY='V';  M= -18,-100,-110,-106, -37, -72,-106,  57,-103,  10,   7,-103,-106, -56,-106, -94,  20,  68,-106,   8;
/M: SY='T';  M= -22,  10, -16, -51,   3, -21,   7, -36,  21, -27, -18,  -3,-100,  28,  22,  15,  49, -14,-106,  -5;
/M: SY='S';  M= -29,-102,   0,  23, -60, -41,  35,  -7, -32, -92,   5,  -3, -51,  25, -31,  38,  34,  21,-108,  19;
/M: SY='H';  M= -21, -42, -60,  11,  18,-105,  72,  13, -53, -15,   1, -91, -27, -34,  15,  -3,   8,  23,  12,  23;
/M: SY='Q';  M= -31,-106,  30,  -5, -48,-100,   9,  -5,  28, -36, -90,   0,   0,  41,  31,   2,  23, -16,-108,  -2;
/M: SY='L';  M= -46,-102,-109,-103,   2,-111,-100,  41, -97,  64, -69, -50, -29, -39,  20,  -4, -90,  15,-103, -85;
/M: SY='T';  M= -69,   9,  25, -14, -48, -10,  38, -40, -21, -10, -29,  21, -48,  -6, -12,  26,  64, -69, -24, -93;
/I:         I=-19; MI=0; MD=-49; IM=0; DM=-49;
/M: SY='P';  M=  10, -34,  36,  46,-109, -31, -89, -57,   2, -63, -98,   7,  47,  26,  -2,  24, -42,-101,-111, -38;
/M: SY='Q';  M= -35,-107,  43,  17, -57,  21, -17, -58,  27, -29, -96,  23,  10,  46, -13,  19, -51,-103,-111, -98;
/M: SY='D';  M= -93, -30, 100, -21,-111,  25,  28, -49, -56, -83,-104,  -2, -59, -40, -95, -85,   4, -26,  -6, -98;
/I:         I=-38; MD=-97;
/M: SY='E';  M= -96,-113,  66,  69,-113, -42, -18,-112,   7, -51,-104, -45, -97,  21, -21,  -8, -31, -66,  -9, -44; D=-38;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='F';  M= -47, -19,-112,-108, 103, -55, -34, -18, -36, -12,  29,-103,-112,-107, -19,-100, -33,   2, -81,  22;
/M: SY='L';  M= -63,-101,-115,-109,   4,-116,-103,  47,-107,  67,  40,-110,-111,-103,-107,-104, -91,  35,-102, -43;
/I:         I=-2; MD=-6;
/M: SY='I';  M= -59,-103,-116,-111, -40,-118,-113,  78,-109,  28, -68,-109,-109,-107,-110,-102, -51,  63,-109, -89; D=-2;
/I:         I=-2; MD=-6;
/M: SY='L';  M= -16,-101,-114,-107, -10, -57,-102,  27,-107,  71,  44,-109,-111,-102,-106, -59, -34,  17,-104, -86; D=-2;
/I:         I=-2; MD=-6;
/M: SY='A';  M=  79,  42, -99, -96, -47,  30, -28, -98, -96, -69,  -1, -47,-101, -93,-100,  -3, -32, -55,-105,   8; D=-2;
/I:         I=-2; MD=-6;
/M: SY='C';  M= -80,  83, -90, -93,-103, -90, -95,-101, -91,-103, -98,  13, -98, -89, -97,  80,  69, -93,-120,-100; D=-2;
/I:         I=-2; MD=-6;
/M: SY='D';  M= -55,-112, 117, -38,-118, -96, -24,-117, -33,-115,-112, -10, -45, -33, -49, -87, -89,-113,-131,-101; D=-2;
/I:         I=-2; MD=-6;
/M: SY='G';  M= -81,-108, -95, -35,-114, 102,-101,-119, -55,-115, -17, -82, -99, -31,-105, -81, -52,-114,-106,-108; D=-2;
/I:         I=-2; MD=-6;
/M: SY='L';  M= -96,-102,-116,-110, -10,-118,-106,  49,-109,  73, -28,-112,-113,-105,-108,-106, -92,  34,-104, -85; D=-2;
/I:         I=-2; MD=-6;
/M: SY='W';  M=-102,-116,-118,-109,  59,-106,-109, -54,-102, -91, -21, -62,-110,-103,-105, -18,  22,-101, 154,  37; D=-2;
/I:         I=-2; MD=-6;
/M: SY='D';  M= -96, -48,  99,  50, -67, -97, -84,-115, -26,-113,-109,  39, -97,  -7, -90, -26, -88,-112,-125,-102; D=-2;
/I:         I=-2; MD=-6;
/M: SY='V';  M= -20,   6, -97, -99, -17, -30,  16, -51,   1, -63,  42,  46, -24, -95, -49, -39, -15,  59,-107,  32; D=-2;
/I:         I=-2; MD=-6;
/M: SY='M';  M= -95,-103,-113,-107,  24,-114,-100,   7, -69,  48,  80, -49, -21,-101, -25,-102, -28,  41,-104, -40; D=-2;
/I:         I=-2; MD=-6;
/M: SY='S';  M= -19,-103,   7,  14, -28, -31, -37,-105, -21,-106, -46,  15,  25, -84, -34,  72,  23,-100,-111,  -7; D=-2;
/I:         I=-2; MD=-6;
/M: SY='N';  M= -92,-107,  36,  18,-106, -25,   5, -14, -11,-107, -36,  73,  30, -84, -32,  31, -51, -71,-116,  -4; D=-2;
/I:         I=-2; MD=-6;
/M: SY='Q';  M= -49, -20,  31,  56,-114,-102, -22,-110,  10,-108,-101,   8, -43,  76, -26, -17, -12, -46,-114, -39; D=-2;
/I:         I=-2; MI=0; MD=-6; IM=0; DM=-6;
/M: SY='E';  M= -32,-113,  37,  87,-111,-106, -89,-109, -31, -33,  -7,  -5, -96,  12, -25, -90, -13, -77,-115, -33; D=-2;
/I:         I=-2; DM=-6;
/M: SY='V';  M=  52,-101,-111,-105, -24,-104,-109,  20,-104,  12,  -9, -45,-109,-103, -53, -92, -32,  57,-112, -96; D=-2;
/I:         I=-2; DM=-6;
/M: SY='V';  M=   2,  46,-109, -24, -22,-111, -27,  23, -58, -38,  -5, -35, -23, -50,-107, -97, -33,  71,-114, -15; D=-2;
/I:         I=-2; DM=-6;
/M: SY='D';  M= -10,-110,  75,  16,-114, -15, -32,-111, -20, -36,-103,  -8,-101,  32,  12,  25, -52,-107,-120,-102; D=-2;
/I:         I=-2; DM=-6;
/M: SY='I';  M= -37,-106,-110, -20,  46,-115,   4,  53, -48,  37,  15, -60,-110, -29,-105,-102, -25,   9,-100, -17; D=-2;
/I:         I=-2; DM=-6;
/M: SY='V';  M=  16,  -1,-114,-107, -34,-111,-112,  33,-105,   3, -30,-108,-110, -41, -55, -55, -87,  78,  -2, -93; D=-2;
/I:         I=-2; DM=-6;
/M: SY='R';  M= -11, -12, -54, -24, -62, -13,  29, -63,  37, -28,   9, -35,-102,  31,  64,  -2, -17, -49,   6, -93; D=-2;
/I:         I=-2; DM=-6;
/M: SY='S';  M= -19, -43,  20,  22, -64, -18,  15, -59,  18, -42, -37,  26, -21,  25,  14,  39, -29, -66, -11, -44; D=-2;
/I:         I=-2; DM=-6;
/M: SY='H';  M= -28,  32, -50, -31,  39, -16,  44,   4, -26, -12, -29,  18,-105,  20,   2,   8,  -5,  -2,  20, -20; D=-2;
/I:         I=-2; DM=-6;
/M: SY='L';  M=   2, -41, -98,   2, -10, -75,   1, -15,  14,  38, -10, -56,  35, -28,  24, -55, -13,  -1,-106, -46; D=-2;
/I:         I=-2; DM=-6;
/M: SY='D';  M=   3,-104,  42,  30,-106,  -4,   0,-104,  11, -45, -26,  39, -55, -48,  19,  28, -13, -50,-113, -37; D=-2;
/I:         I=-2; DM=-6;
/M: SY='P';  M=  -5,-107,  14,   7,-106,  11,  -7, -99,  14, -10, -31,  -2,  42,  29,  11,  11,   0, -36,-111, -99; D=-2;
/I:         I=-2; MI=0; MD=-6; IM=0; DM=-6;
/M: SY='G';  M=-106, -27,-106, -35,-122,  56,  16,-131, -74,-129,-120,  36,-120,-110,-118, -41,   4,-127,-127,   2; D=-2;
/I:         I=-2; DM=-6;
/M: SY='D';  M= -78,-124,  40, -35, -12,-122,-109, -10, -52,  33, -97, -14,   9,  -5, -13, -77,-108,-102,-124,-107; D=-2;
/I:         I=-2; MI=0; MD=-6; IM=0; DM=-6;
/M: SY='P';  M=   6, -12, -20, -67,   1,-118,-113,-105,  -9, -20,  -4, -55,  45,  -1,-112, -44,-107,  -7,-121, -10; D=-2;
/I:         I=-2; DM=-6;
/M: SY='S';  M=   8, -25, -58,  27, -56, -27, -18, -46,   0,  -8,  19, -93,-104,  22,  -7,  30,   7, -23,-115,-101; D=-2;
/I:         I=-2; DM=-6;
/M: SY='E';  M= -18,-110,   5,  45, -21,-105, -45, -36,  30,  -3,  35, -49,   6,  12, -32,  -3, -16, -38,  -5, -41; D=-2;
/I:         I=-2; DM=-6;
/M: SY='A';  M=  57,  14, -40, -26,  -8, -51,-104,  17, -23, -32, -12, -98, -30, -47, -11,  -6, -47,  15,  -4, -97; D=-2;
/I:         I=-2; DM=-6;
/M: SY='A';  M=  74,  52, -63, -54, -10, -90,-102, -24, -38, -32, -92, -48,-103, -94,-100,  33, -84, -14,  -7, -98; D=-2;
/I:         I=-2; DM=-6;
/M: SY='K';  M= -30,-106,  18,  22, -52, -40,  32, -65,  47, -15, -16,  20, -98,  39,  18, -16,  14, -45,-110, -47;
/M: SY='K';  M= -17,   7, -20,  39, -28, -64,  13, -30,  46, -14,   5, -13, -45,   9,  42,  -1, -89, -34,-106, -26;
/M: SY='L';  M= -18,-100,-109, -27,  -9,-112,-100,  10, -39,  73,  23,-106,-109, -98,-102, -61,  -2,  18,-104, -85;
/M: SY='C';  M=  20,  48,-103, -97, -57, -27, -26,  21,  -6,  17,  -6, -45,-105,  12,  -7, -44, -17,  45,-108, -18;
/M: SY='D';  M= -26,-107,  65,  47,-108, -32,   1,-108,  22, -81,  -7,  18, -25,  24,  -3,  -9,   0,-104,-113, -22;
/M: SY='Y';  M=  -9, -33, -14,  37, -14, -64, -10,  -7,  23,  11,  -2,  24,-100,  16,  -5, -88,   6, -48, -99,  41;
/M: SY='A';  M=  74,  26, -58, -92,-103,   4, -98, -23, -12, -24, -91,   6,  10, -45, -96,  -9,  -3, -53, -11,-100;
/M: SY='I';  M= -42,-105,-102, -24,  -6,-110,  -4,  53, -54,  39, -73, -11,-106,  46,  -9, -96, -49,  17, -99,  26;
/M: SY='S';  M=  36,  -1,  -7,  23, -50,  22, -91, -61, -11, -53, -96,  -7, -51,  17,  24,  42, -38, -97,-108, -32;
/M: SY='R';  M= -18,-108,  -4, -55, -18, -16,  28, -19,  -5, -33, -13,   0,  -8, -41,  68,  -7, -33, -29, -97,  55;
/M: SY='G';  M=  -4, -35,  12, -57,-102,  69,  28, -21, -23, -31, -40, -34,-101, -30,  35, -30, -95,-102,  56, -45;
/I:         I=-16; MD=-41;
/M: SY='S';  M= -14,  12, -39, -91, -15,  28, -91,-102,  17, -30, -95, -11, -57, -85,  36,  57,  20, -98,-105,  10; D=-16;
/I:         I=-16; MD=-41;
/M: SY='K';  M=   4, -10, -35,  15,-104,  19,  27,-101,  36, -16,  12, -21, -22,   6,  34,   3,  -3, -62,-110, -96; D=-16;
/I:         I=-16; MI=0; MD=-41; IM=0; DM=-41;
/M: SY='D';  M= -97,-111, 118,   1,-118, -50, -84,-117, -29,-115,-113, -37, -97, -83, -41, -51, -88,-113,-130,-101;
/M: SY='N';  M= -63,-104,  90, -74,-112, -87, -79,-111, -52,-114,-106,  98,-100, -83, -90,   3, -81,-110,-129,-102;
/M: SY='I';  M= -30,  24,-111, -52, -16,-113,-107,  82,-104, -18,  60,-103,-105,-102,-107, -46,  -1,  36,-107, -88;
/M: SY='T';  M= -26, -17, -88, -91, -99, -93, -17, -93, -89, -48, -27, -11, -93, -89, -95,  57, 100, -86,-117, -96;
/M: SY='V';  M=  24,  49,-111,-106, -38,-108,-110,  33,-104, -14, -14,-105,-108,-104,-106, -93, -57,  81,-112, -37;
/M: SY='I';  M= -44, -41,-112,-108, -14,-114, -19,  74,-105,  10,  62, -47,-106,-102,-106, -99,  -8,  51,-107, -86;
/M: SY='V';  M= -34,  46,-113,-108, -82,-113,-109,  36,-106,  26, -25,-107,-110,-105,-107, -48, -86,  80,-111, -14;
/M: SY='V';  M=   6, -99,-110,-105, -86, -45,-109,  50,-103,   6, -21,-103,-106,-101, -52,   2, -55,  76,-111, -92;
/M: SY='F';  M= -53,  32,  22, -11,  45, -65,   3, -42, -29, -65, -91,   1,  10,  41,  41,  10, -26, -34, -98,  26;
/M: SY='F';  M= -97,-102,-113,-107,  65,-115,-101,  14,-101,  63, -69, -52,-113,-103,  10,-104, -92,  31, -95, -75;
/I:         E1=0; IE=-380; DE=-380;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 302 in 302 different sequences
Number of true positive hits 302 in 302 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] PPM-type phosphatase
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
302 sequences

AZR1_SCHPO  (Q09189), BIP2C_ORYSI (Q6J2K6), BIP2C_ORYSJ (Q10QL5), 
CYAA_LACKL  (P23466), CYAA_NEUCR  (Q01631), CYAA_PODAS  (Q01513), 
CYAA_SCHPO  (P14605), CYAA_USTMA  (P49606), CYAA_YEAST  (P08678), 
FEM2_CAEEL  (P49594), ICFG_SYNY3  (P37979), ILKAP_BOVIN (Q0IIF0), 
ILKAP_HUMAN (Q9H0C8), ILKAP_MOUSE (Q8R0F6), ILKAP_RAT   (Q9Z1Z6), 
MTDRP_MYCTO (P9WLZ6), MTDRP_MYCTU (P9WLZ7), P2C01_ARATH (Q9LR65), 
P2C01_ORYSJ (Q942P9), P2C02_ARATH (Q8RX37), P2C02_ORYSJ (Q9FYN7), 
P2C03_ARATH (Q9LNW3), P2C03_ORYSJ (Q0JMD4), P2C04_ARATH (Q9LQN6), 
P2C04_ORYSJ (Q5JJY4), P2C05_ARATH (O80492), P2C05_ORYSJ (Q5JKN1), 
P2C06_ARATH (Q9SA22), P2C06_ORYSJ (Q0JLP9), P2C07_ARATH (Q9LNP9), 
P2C07_ORYSJ (Q0JL75), P2C08_ARATH (Q9LMT1), P2C08_ORYSJ (Q5SN75), 
P2C09_ARATH (Q9LME4), P2C09_ORYSJ (Q5N9N2), P2C10_ARATH (Q9S9Z7), 
P2C10_ORYSJ (Q67UX7), P2C11_ARATH (Q8VZN9), P2C11_ORYSJ (Q6ETK3), 
P2C12_ARATH (Q9FX08), P2C12_ORYSJ (Q6Z8B9), P2C13_ARATH (Q9LNF4), 
P2C13_ORYSJ (Q6EN45), P2C14_ARATH (Q9FXE4), P2C14_ORYSJ (Q6K6N7), 
P2C15_ARATH (Q9M9C6), P2C15_ORYSJ (Q6YTI2), P2C16_ARATH (Q9CAJ0), 
P2C16_ORYSJ (Q6K1U4), P2C17_ARATH (Q8L7I4), P2C17_ORYSJ (Q6K1U0), 
P2C18_ARATH (Q8RXZ4), P2C18_ORYSJ (A3A8Q4), P2C19_ARATH (Q9SL76), 
P2C19_ORYSJ (Q0DZT4), P2C20_ARATH (Q9SIU8), P2C20_ORYSJ (Q6K5I0), 
P2C21_ARATH (O81716), P2C21_ORYSJ (A3A8W2), P2C22_ARATH (Q9SLA1), 
P2C22_ORYSJ (A3A8W6), P2C23_ARATH (Q9ZV25), P2C23_ORYSJ (Q6H7J4), 
P2C24_ARATH (Q9ZW21), P2C24_ORYSJ (Q6H7J3), P2C25_ARATH (O80871), 
P2C25_ORYSJ (Q6ZHC8), P2C26_ARATH (O64730), P2C26_ORYSJ (Q6ZGY0), 
P2C27_ARATH (P93006), P2C27_ORYSJ (Q69QZ0), P2C28_ARATH (O64583), 
P2C28_ORYSJ (Q10S32), P2C29_ARATH (O82302), P2C29_ORYSJ (Q8H063), 
P2C30_ARATH (Q9XEE8), P2C30_ORYSJ (Q84JI0), P2C31_ARATH (Q940A2), 
P2C31_ORYSJ (Q10NB9), P2C32_ARATH (Q8RWN7), P2C32_ORYSJ (Q10MX1), 
P2C33_ARATH (Q9M8R7), P2C33_ORYSJ (Q10MN6), P2C34_ARATH (Q9M9W9), 
P2C34_ORYSI (Q5MFV5), P2C34_ORYSJ (Q94H98), P2C35_ARATH (Q7XJ53), 
P2C35_ORYSJ (Q84T94), P2C36_ARATH (Q9SR24), P2C36_ORYSJ (Q7Y138), 
P2C37_ARATH (P49598), P2C37_ORYSJ (Q7XP01), P2C38_ARATH (Q9LHJ9), 
P2C38_ORYSJ (Q7XW27), P2C39_ARATH (Q9LDA7), P2C39_ORYSJ (Q7XVF9), 
P2C40_ARATH (Q9LUS8), P2C40_ORYSJ (Q7XTC7), P2C41_ARATH (Q9LRZ4), 
P2C41_ORYSJ (Q7XQU7), P2C42_ARATH (Q0V7V2), P2C42_ORYSJ (Q7XU84), 
P2C43_ARATH (Q9LUU7), P2C43_ORYSJ (Q7XUC5), P2C44_ARATH (Q9LW60), 
P2C44_ORYSJ (Q0JAA0), P2C45_ARATH (Q3EAZ3), P2C45_ORYSJ (Q7XR06), 
P2C46_ARATH (Q9SD12), P2C46_ORYSJ (A3AZ89), P2C47_ARATH (Q9SD02), 
P2C47_ORYSJ (Q6AUQ4), P2C48_ARATH (Q94CL8), P2C48_ORYSJ (Q6L482), 
P2C49_ARATH (Q3EAF9), P2C49_ORYSJ (Q65XG6), P2C50_ARATH (Q9M1V8), 
P2C50_ORYSJ (Q6L5H6), P2C51_ARATH (Q93YS2), P2C51_ORYSJ (Q65XK7), 
P2C52_ARATH (Q8GY60), P2C52_ORYSJ (Q6L5C4), P2C53_ARATH (Q9SUF4), 
P2C53_ORYSJ (Q6L4R7), P2C54_ARATH (Q9T010), P2C54_ORYSJ (Q5SMK6), 
P2C55_ARATH (Q9SUK9), P2C55_ORYSJ (Q652Z7), P2C56_ARATH (P49597), 
P2C56_ORYSJ (Q0DBU3), P2C57_ARATH (P49599), P2C57_ORYSJ (Q69VD9), 
P2C58_ARATH (Q93YW5), P2C58_ORYSJ (Q67UP9), P2C59_ARATH (Q8RXV3), 
P2C59_ORYSJ (Q5Z6F5), P2C60_ARATH (Q9SZ53), P2C60_ORYSJ (Q5Z8P0), 
P2C61_ARATH (O82637), P2C61_ORYSJ (Q7XHN8), P2C62_ARATH (Q93V88), 
P2C62_ORYSJ (Q0D673), P2C63_ARATH (O81760), P2C63_ORYSJ (Q0D629), 
P2C64_ARATH (Q5PNS9), P2C64_ORYSJ (Q8H4S6), P2C65_ARATH (Q6NKS1), 
P2C65_ORYSJ (Q8H2T0), P2C66_ARATH (Q9LZ86), P2C66_ORYSJ (Q6ZKL8), 
P2C67_ARATH (Q501F9), P2C67_ORYSJ (Q0J2R1), P2C68_ARATH (Q84JD5), 
P2C68_ORYSJ (Q0J2L7), P2C69_ARATH (Q8LAY8), P2C69_ORYSJ (Q67J17), 
P2C70_ARATH (P46014), P2C70_ORYSJ (Q653S3), P2C71_ARATH (Q4PSE8), 
P2C71_ORYSJ (Q339D2), P2C72_ARATH (Q9XGZ9), P2C72_ORYSJ (Q7XCJ7), 
P2C73_ARATH (Q0WRB2), P2C73_ORYSJ (Q2RBJ6), P2C74_ARATH (Q9FG61), 
P2C74_ORYSJ (Q53Q11), P2C75_ARATH (Q9FLI3), P2C75_ORYSJ (Q2R637), 
P2C76_ARATH (Q94AT1), P2C76_ORYSJ (A3CCP9), P2C77_ARATH (O04719), 
P2C77_ORYSJ (Q2QWE3), P2C78_ARATH (Q9FIF5), P2C78_ORYSJ (Q2QN36), 
P2C79_ARATH (Q9FKX4), P2C80_ARATH (Q9LVQ8), PDP1_BOVIN  (P35816), 
PDP1_HUMAN  (Q9P0J1), PDP1_MOUSE  (Q3UV70), PDP1_PONAB  (Q5RA52), 
PDP1_RAT(O88483), PDP1_YEAST  (Q12511), PDP2_HUMAN  (Q9P2J9), 
PDP2_MOUSE  (Q504M2), PDP2_RAT(O88484), PDP2_YEAST  (P25646), 
PHLP1_HUMAN (O60346), PHLP1_MOUSE (Q8CHE4), PHLP1_RAT   (Q9WTR8), 
PHLP2_HUMAN (Q6ZVD8), PHLP2_MOUSE (Q8BXA7), PHLPP_CAEEL (Q09564), 
PHLPP_DROME (Q9VJ07), PHPP_STREE  (Q8KY51), PHPP_STRP2  (Q04J42), 
PHPP_STRR6  (Q8DNR9), PP2C1_PARTE (P49444), PP2C1_SCHPO (P40371), 
PP2C1_YEAST (P35182), PP2C2_CAEEL (P49596), PP2C2_PARTE (A0BLX0), 
PP2C2_SCHPO (Q09172), PP2C2_YEAST (P39966), PP2C3_PARTE (A0BQL0), 
PP2C3_SCHPO (Q09173), PP2C3_YEAST (P34221), PP2C4_PARTE (A0DTY1), 
PP2C4_SCHPO (O14156), PP2C4_YEAST (P38089), PP2C5_PARTE (A0CUB5), 
PP2C5_SCHPO (O14189), PP2C6_PARTE (A0DSB3), PP2C7_YEAST (P38797), 
PP2C_LEICH  (P36982), PP2C_STRP6  (Q5XAP6), PP2D1_HUMAN (A8MPX8), 
PP2D1_MOUSE (Q8BVT6), PPH_MYCGE   (P47354), PPH_MYCPN   (P75525), 
PPM1A_BOVIN (O62829), PPM1A_CAEEL (Q19775), PPM1A_HUMAN (P35813), 
PPM1A_MOUSE (P49443), PPM1A_RABIT (P35814), PPM1A_RAT   (P20650), 
PPM1B_BOVIN (O62830), PPM1B_HUMAN (O75688), PPM1B_MOUSE (P36993), 
PPM1B_RAT   (P35815), PPM1D_HUMAN (O15297), PPM1D_MOUSE (Q9QZ67), 
PPM1E_HUMAN (Q8WY54), PPM1E_MOUSE (Q80TL0), PPM1E_RAT   (Q80Z30), 
PPM1F_HUMAN (P49593), PPM1F_MOUSE (Q8CGA0), PPM1F_RAT   (Q9WVR7), 
PPM1G_BOVIN (P79126), PPM1G_CAEEL (P49595), PPM1G_HUMAN (O15355), 
PPM1G_MACFA (Q4R4V2), PPM1G_MOUSE (Q61074), PPM1G_RAT   (F1LNI5), 
PPM1H_DANRE (Q05AL2), PPM1H_HUMAN (Q9ULR3), PPM1H_MOUSE (Q3UYC0), 
PPM1H_RAT   (Q5M821), PPM1H_XENTR (Q28DF4), PPM1J_HUMAN (Q5JR12), 
PPM1J_MOUSE (Q149T7), PPM1J_RAT   (Q641Y6), PPM1K_BOVIN (Q2PC20), 
PPM1K_HUMAN (Q8N3J5), PPM1K_MOUSE (Q8BXN7), PPM1K_PONAB (Q5R522), 
PPM1K_RAT   (A6K136), PPM1K_XENLA (Q6ING9), PPM1L_BOVIN (A5PJZ2), 
PPM1L_HUMAN (Q5SGD2), PPM1L_MOUSE (Q8BHN0), PPM1M_HUMAN (Q96MI6), 
PPM1M_MOUSE (Q8BU27), PPM1N_HUMAN (Q8N819), PPM1N_MOUSE (Q8BGL1), 
PPTC7_DANRE (Q5U3N5), PPTC7_HUMAN (Q8NI37), PPTC7_MOUSE (Q6NVE9), 
PPTC7_XENLA (Q6GR25), PRPC_BACSU  (O34779), PSTP_MYCTO  (P9WHW4), 
PSTP_MYCTU  (P9WHW5), PTC71_DROAN (B3MTI8), PTC71_DROER (B3P5D3), 
PTC71_DROGR (B4JYN1), PTC71_DROME (Q9VAH4), PTC71_DROMO (B4K616), 
PTC71_DROPE (B4G653), PTC71_DROPS (Q29AP0), PTC71_DROSE (B4HZE7), 
PTC71_DROSI (B4R089), PTC71_DROVI (B4M5T5), PTC71_DROWI (B4NBL6), 
PTC71_DROYA (B4PPK3), RSBP_BACSU  (O07014), RSBU_BACSU  (P40399), 
RSBX_BACSU  (P17906), SP2E_BACSU  (P37475), SP2E_PRIMG  (P49600), 
SPNA_DICDI  (O15743), STP1_LISIN  (Q92AI7), STP1_LISMF  (Q71YJ5), 
STP1_LISMO  (Q8Y678), STP1_LISW6  (A0AJS6), TAB1_CAEEL  (G5EEM6), 
TAB1_HUMAN  (Q15750), TAB1_MOUSE  (Q8CF89), Y0417_DROME (Q7K4Q5), 
Y2105_DICDI (Q54T01), Y9461_DICDI (Q54WS9), Y9801_DROME (Q0KIA2), 
YR306_MIMIV (Q5UPY7), YR307_MIMIV (Q5UPZ7)
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PDB
[Detailed view]
91 PDB

1A6Q; 1TXO; 2CM1; 2IQ1; 2J4O; 2P8E; 2PNQ; 2POM; 2POP; 3FXJ; 3FXK; 3FXL; 3FXM; 3FXO; 3JRQ; 3KB3; 3KDJ; 3KE6; 3MQ3; 3NMN; 3NMT; 3NMV; 3QN1; 3RT0; 3T91; 3T9Q; 3UJG; 3UJK; 3UJL; 3W40; 3W41; 3W42; 3W43; 3W44; 3W45; 3ZVU; 4DA1; 4DS8; 4JND; 4LA7; 4LG5; 4LGA; 4LGB; 4N0G; 4OIC; 4RA2; 4RAF; 4RAG; 4WVO; 4YZG; 4YZH; 5GWO; 5GWP; 5JO1; 5JO2; 5MN0; 5MQH; 5NZZ; 5OR2; 5OR6; 5UCG; 5VR7; 5VRO; 5VS5; 5VSQ; 5VSR; 5VT7; 5ZCG; 5ZCH; 5ZCL; 5ZCU; 6AE9; 6AK7; 6B67; 6V0T; 6ZUC; 7AVW; 7KPR; 7L4I; 7L4J; 7MWN; 7N0Z; 8AY3; 8AY6; 8AY7; 8AY8; 8AY9; 8AYA; 8EY0; 8T2J; 8XI8
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