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annotation rule: PRU01082

General rule information [?]

Accession PRU01082
Dates 4-FEB-2015 (Created)
22-NOV-2019 (Last updated, Version 4)
Data class Domain
Predictors PROSITE; PS51746; PPM_2
Name PPM-type phosphatase domain
Function The 300-residue protein phosphatase Mg(2+)- or Mn(2+)-dependent (PPM)-type phosphatase domain that catalyzes the dephosphorylation of phosphoserine- and phosphothreonine-containing protein.

Propagated annotation [?]

Description [?]

+ RecName: EC;

Comments [?]

Catalytic activity RHEA:20629: H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate
RHEA:47004: H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate
Cofactor Mg(2+)
Note: Binds 2 magnesium or manganese ions per subunit

Cross-references [?]

PROSITE PS01032; PPM_1; 1;

Gene Ontology [?]

GO:0046872; Molecular function: metal ion binding.

Keywords [?]

Features [?]

From: PS51746
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       PPM-type phosphatase #        

Additional information [?]

Size range 96-574 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q7XR06 (P2C45_ORYSJ)
Viruses; Mimivirus
Comments None


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UniProtKB rule member sequences [?]