Home  |  Contact
Entry: PS51803

General information about the entry

Entry name [info] ZF_C2HC_RNF
Accession [info] PS51803
Entry type [info] MATRIX
Date [info] 01-JUN-2016 CREATED;
13-FEB-2019 DATA UPDATE;
10-FEB-2021 INFO UPDATE.
PROSITE Doc. [info] PDOC51803
Associated ProRule [info] PRU01144

Name and characterization of the entry

Description [info] Zinc finger C2HC RNF-type profile.
Matrix / Profile [info] 
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=20;
/DISJOINT: DEFINITION=PROTECT; N1=3; N2=18;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.2985992; R2=0.0061719; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1499.4128418; R2=0.2231357; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1167; H_SCORE=1760; N_SCORE=10.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=519; H_SCORE=1615; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-66; D=-60; I=-60; B1=-600; E1=-600; MI=-180; MD=-180; IM=-180; DM=-180;

...
 
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-180; BD=-180;
/M: SY='C';  M=-113, 153,-133,-133,-121,-129,-132,-126,-129,-119,-119,-119,-143,-136,-135,-116,-113, -34,-150, -42;
/M: SY='R';  M= -30,-125, -92, -47,-124, -49,  50, -64,  45,-121,  23,  -8,-119, -98,  68,  23,  30,-119,-131,-112;
/M: SY='G';  M= -28,  72,-112,  36,-122,  80,-118,-132,-116, -46,-120,-108,-121,-113,-123,-105,-117,-126,  19,  16;
/M: SY='C';  M=-113, 154,-133,-132,-121,-128,-132,-127,-128, -45,-118,-119,-143,-136,-135,-116,-113,-116,-151,-132;
/M: SY='G';  M= -25, -68,  17,  25,-131,  49,  -3,-133,  -3,-131,-122,  31,-118, -39,  38,  29, -76,-127,-132,-121;
/M: SY='K';  M= -27,-124,-107, -13,-126,-120,-111,-119,  91,-121,   3, -25,-115,   8, -87, -73,  46, -23,-128,-117;
/M: SY='Q';  M= -94,-126, -72,   6,-125,-117, -53,-115,  58, -24,  12,  25, -41,  97, -30, -39, -53, -16,-124,-112;
/I:         I=-18; MI=0; MD=-55; IM=0; DM=-55;
/M: SY='V';  M=-106,-116,-131,-125,  36,-131,-122,  31, -61, -12,  78,-124,-125,-121,-121,-117,-103,  83,-121, -40;
/M: SY='C';  M= -72,  85,-115, -43,  33, -25,-111, -19,  31, -33,-106,-107, -46,-108,  20,  15,  33, -18,-115,  41;
/M: SY='L';  M=-115,-117,-132,-125,  39,-133,-116, -33,-125,  90,  -4,-130,-131,-120,-122,-124,-111, -34,-113, -38;
/M: SY='S';  M=  15,-114,-107,-107,-111, -76,  25, -38, -39, -57, -45, -72,-114, -99,-109,  99, -90, -44,-121,  36;
/M: SY='K';  M=-111, -53,  21,  34,-120,-119, -41,-125,  88, -77,-113, -98,-113,  42,  28,-105,-107,-122,  24,  12;
/M: SY='M';  M=-110,-117,-130,-122, -22,-125,-105,  12,-116,  13, 142,-119,-120,-108,-114,-118, -25, -88,-119, -18;
/M: SY='R';  M=-114,-131,-110, -98,-123,-124,   6,-130,  -5,-122,-111,-103,-122, -88, 121,-108,-113,-124,-124,-109;
/M: SY='S';  M=  60,-115, -40, -12,-120, -33,  54, -79,-106, -24,-108, -36, -79,  29,-109,  66, -54, -31,-128,-111;
/M: SY='H';  M=-117,-129,-101,-101,-115,-119, 157,-134,-106,-116,-101, -90,-117, -95,-100,-106,-115,-133,-151, -84;
/M: SY='Y';  M=  15,-118,-117,-117, -63,-121,  13,  45,-114, -11, -15,  -3,-121, -23,-116,-104,  43,  37,-111,  73;
/M: SY='A';  M=  54,-117,-108,-102,-119, -34,-108,-118,  51,-118, -31, -35,-114, -97,  49,  43,   2, -56,-122,  -8;
/M: SY='S';  M=   7,-111,-103,-106,-119,-103,-109,-113,-105,-117, -19,  23,-111,-102,-111,  84,  79, -66,-132,-114;
/M: SY='C';  M=-109, 159,-129,-129,-119,-124,-129,-126,-124,-116,-117,-115,-139,-132,-131,-111,-109,-113,-149,-130;
/I:         E1=0; IE=-180; DE=-180;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2021_01 which contains 564'277 sequence entries.


Total number of hits 19 in 19 different sequences
Number of true positive hits 19 in 19 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] ZN_FING
Feature description [info] C2HC RNF-type
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 19 sequences 

RN114_BOVIN (Q4U5R4    ), RN114_HUMAN (Q9Y508    ), RN114_MOUSE (Q9ET26    ), 

RN114_PANTR (Q6J212    ), RN114_PIG   (Q6J1I8    ), RN114_RAT   (Q6J2U6    ), 
RN125_HUMAN (Q96EQ8    ), RN125_MACFA (Q95KF1    ), RN125_MOUSE (Q9D9R0    ), 
RN138_BOVIN (Q32LN5    ), RN138_HUMAN (Q8WVD3    ), RN138_MOUSE (Q9CQE0    ), 
RN138_RAT   (Q99PD2    ), RN138_XENLA (Q1L721    ), RN166_CHICK (Q5F3B2    ), 
RN166_HUMAN (Q96A37    ), RN166_MOUSE (Q3U9F6    ), RN166_RAT   (Q6J1I7    ), 
RN166_XENLA (Q3KPU8    )
» more

PDB
[Detailed view]		 1 PDB

5DKA

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission