PROSITE entry PS51803
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS51803 |
| Entry name [info] | ZF_C2HC_RNF |
| Accession [info] | PS51803 |
| Entry type [info] | MATRIX |
| Date [info] |
01-JUN-2016 CREATED;
13-FEB-2019 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51803 |
| Associated ProRule [info] | PRU01144 |
Name and characterization of the entry
| Description [info] | Zinc finger C2HC RNF-type profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=20; /DISJOINT: DEFINITION=PROTECT; N1=3; N2=18; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.2985992; R2=0.0061719; TEXT='-LogE'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1499.4128418; R2=0.2231357; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=1167; H_SCORE=1760; N_SCORE=10.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=519; H_SCORE=1615; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-66; D=-60; I=-60; B1=-600; E1=-600; MI=-180; MD=-180; IM=-180; DM=-180; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-180; BD=-180; /M: SY='C'; M=-113, 153,-133,-133,-121,-129,-132,-126,-129,-119,-119,-119,-143,-136,-135,-116,-113, -34,-150, -42; /M: SY='R'; M= -30,-125, -92, -47,-124, -49, 50, -64, 45,-121, 23, -8,-119, -98, 68, 23, 30,-119,-131,-112; /M: SY='G'; M= -28, 72,-112, 36,-122, 80,-118,-132,-116, -46,-120,-108,-121,-113,-123,-105,-117,-126, 19, 16; /M: SY='C'; M=-113, 154,-133,-132,-121,-128,-132,-127,-128, -45,-118,-119,-143,-136,-135,-116,-113,-116,-151,-132; /M: SY='G'; M= -25, -68, 17, 25,-131, 49, -3,-133, -3,-131,-122, 31,-118, -39, 38, 29, -76,-127,-132,-121; /M: SY='K'; M= -27,-124,-107, -13,-126,-120,-111,-119, 91,-121, 3, -25,-115, 8, -87, -73, 46, -23,-128,-117; /M: SY='Q'; M= -94,-126, -72, 6,-125,-117, -53,-115, 58, -24, 12, 25, -41, 97, -30, -39, -53, -16,-124,-112; /I: I=-18; MI=0; MD=-55; IM=0; DM=-55; /M: SY='V'; M=-106,-116,-131,-125, 36,-131,-122, 31, -61, -12, 78,-124,-125,-121,-121,-117,-103, 83,-121, -40; /M: SY='C'; M= -72, 85,-115, -43, 33, -25,-111, -19, 31, -33,-106,-107, -46,-108, 20, 15, 33, -18,-115, 41; /M: SY='L'; M=-115,-117,-132,-125, 39,-133,-116, -33,-125, 90, -4,-130,-131,-120,-122,-124,-111, -34,-113, -38; /M: SY='S'; M= 15,-114,-107,-107,-111, -76, 25, -38, -39, -57, -45, -72,-114, -99,-109, 99, -90, -44,-121, 36; /M: SY='K'; M=-111, -53, 21, 34,-120,-119, -41,-125, 88, -77,-113, -98,-113, 42, 28,-105,-107,-122, 24, 12; /M: SY='M'; M=-110,-117,-130,-122, -22,-125,-105, 12,-116, 13, 142,-119,-120,-108,-114,-118, -25, -88,-119, -18; /M: SY='R'; M=-114,-131,-110, -98,-123,-124, 6,-130, -5,-122,-111,-103,-122, -88, 121,-108,-113,-124,-124,-109; /M: SY='S'; M= 60,-115, -40, -12,-120, -33, 54, -79,-106, -24,-108, -36, -79, 29,-109, 66, -54, -31,-128,-111; /M: SY='H'; M=-117,-129,-101,-101,-115,-119, 157,-134,-106,-116,-101, -90,-117, -95,-100,-106,-115,-133,-151, -84; /M: SY='Y'; M= 15,-118,-117,-117, -63,-121, 13, 45,-114, -11, -15, -3,-121, -23,-116,-104, 43, 37,-111, 73; /M: SY='A'; M= 54,-117,-108,-102,-119, -34,-108,-118, 51,-118, -31, -35,-114, -97, 49, 43, 2, -56,-122, -8; /M: SY='S'; M= 7,-111,-103,-106,-119,-103,-109,-113,-105,-117, -19, 23,-111,-102,-111, 84, 79, -66,-132,-114; /M: SY='C'; M=-109, 159,-129,-129,-119,-124,-129,-126,-124,-116,-117,-115,-139,-132,-131,-111,-109,-113,-149,-130; /I: E1=0; IE=-180; DE=-180;» more |
Numerical results [info]
| Total number of hits | 19 in 19 different sequences |
| Number of true positive hits | 19 in 19 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | ZN_FING |
| Feature description [info] | C2HC RNF-type |
| Version [info] | 3 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
19 sequences
RN114_BOVIN (Q4U5R4), RN114_HUMAN (Q9Y508), RN114_MOUSE (Q9ET26), RN114_PANTR (Q6J212), RN114_PIG (Q6J1I8), RN114_RAT (Q6J2U6), RN125_HUMAN (Q96EQ8), RN125_MACFA (Q95KF1), RN125_MOUSE (Q9D9R0), RN138_BOVIN (Q32LN5), RN138_HUMAN (Q8WVD3), RN138_MOUSE (Q9CQE0), RN138_RAT (Q99PD2), RN138_XENLA (Q1L721), RN166_CHICK (Q5F3B2), RN166_HUMAN (Q96A37), RN166_MOUSE (Q3U9F6), RN166_RAT (Q6J1I7), RN166_XENLA (Q3KPU8)» more
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| PDB [Detailed view] |
3 PDB
5DKA; 8GBQ; 8GCB |