ProRule PRU01144

General rule information [?]

Accession PRU01144
Dates 17-JUN-2016 (Created)
19-NOV-2022 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51803; ZF_C2HC_RNF
Name Zinc finger C2HC RNF-type
Function The closely related proteins RNF125/TRAC-1, RNF114 (also known as Zpf313), RNF138 (or NARF) and RNF166 contain, apart from the RING domain, a C2HC (Cys2-His-Cys)- and two C2H2 (Cys2-His2)-type zinc fingers, as well as an ubiquitin interacting motif (UIM).
Scope(s) Eukaryota
Example(s) Q1L721 (RN138_XENLA);

Propagated annotation [?]

Keywords [?]

Gene Ontology [?]

case <Feature:PS51803:1=[CH]> and <Feature:PS51803:4=[CH]> and <Feature:PS51803:16=[CH]> and <Feature:PS51803:20=[CH]>
GO:0008270; Molecular function:zinc ion binding
GO:0046872; Molecular function:metal ion binding

Features [?]

From: PS51803
Key From To Description Tag Condition FTGroup
case <Feature:PS51803:1=C> and <Feature:PS51803:4=C> and <Feature:PS51803:16=H> and <Feature:PS51803:20=C>
ZN_FING from to /note="C2HC RNF-type #"
else case <Feature:PS51803:1=[CH]> and <Feature:PS51803:4=[CH]> and <Feature:PS51803:16=[CH]> and <Feature:PS51803:20=[CH]>
ZN_FING from to /note="C2HC RNF-type #; atypical"
ZN_FING from to /note="C2HC RNF-type #; degenerate"
end case
BINDING 1 1 /ligand="Zn(2+)"
[CH] 1
BINDING 4 4 /ligand="Zn(2+)"
[CH] 1
BINDING 16 16 /ligand="Zn(2+)"
[CH] 1
BINDING 20 20 /ligand="Zn(2+)"
[CH] 1

Additional information [?]

Size range 10-30 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


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UniProtKB rule member sequences [?]