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Entry: PS51864

General information about the entry

Entry name [info] ASTACIN
Accession [info] PS51864
Entry type [info] MATRIX
Date [info] 18-JUL-2018 CREATED;
13-FEB-2019 DATA UPDATE;
13-NOV-2019 INFO UPDATE.
PROSITE Doc. [info] PDOC51864
Associated ProRule [info] PRU01211

Name and characterization of the entry

Description [info] Astacin-like domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=199;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=194;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6554613; R2=0.0092739; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=8961.4394531; R2=14.8759928; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=900; H_SCORE=22350; N_SCORE=11.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=415; H_SCORE=15135; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-45; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='N';  M=  33, -91, -70,   4, -97, -78, -74, -90, -16, -93, -84,  75, -89,  46,  34,  13, -72, -17,-102, -88;
/M: SY='A';  M=  69, -87, -89, -82,   5,   3, -88, -77, -30, -18, -77, -82, -32, -11,  -6,  -8,  -9,  10, -94, -83;
/M: SY='I';  M= -60, -93, -56, -96, -69,-104, -30,  77, -94,  21,  48, -93, -95, -36, -95, -88,   4,  28, -94,  -7;
/M: SY='R';  M=  18, -92, -44, -79, -84,  -1, -82, -29,  18,   3, -76, -15,   6, -13,  40,   1,  14,  -5, -94,   7;
/M: SY='D';  M= -40,   6,  41, -25, -45,  21, -77, -53,   2, -31, -18,   3, -13,  36,  10,  27, -24, -67, -96,  11;
/I:         I=-18; MI=0; MD=-45; IM=0; DM=-45;
/M: SY='D';  M= -27,-100,  41,  -2,  -7, -64, -84, -39,   2, -16, -88,  30,  26,  -4, -16,   0,   2, -68,-105, -44; D=-18;
/I:         I=-18; DM=-45;
/M: SY='E';  M= -41, -98, -31,  39, -85, -58,  -9,   6, -35, -39, -23,  10, -37,  -4,  10,  33,   6, -55,   2,  35; D=-18;
/I:         I=-18; DM=-45;
/M: SY='Y';  M= -25,   6, -44, -47, -47, -94,  11, -52,  24, -40, -22,   9,   5,  20,  28, -30, -18, -89, -82,  75; D=-18;
/I:         I=-18; DM=-45;
/M: SY='R';  M= -86, -97, -36, -77,   2, -98, -17, -24,  48,  26, -73, -80, -37, -24,  65, -82,  14, -60,  -1, -48; D=-18;
/I:         I=-18; DM=-45;
/M: SY='W';  M= -54,-119,-121, -99, -62, -94,-119, -92, -90, -60, -41,-114, -99, -91, -39,-101,-106,-105, 176, -49;
/M: SY='P';  M= -79, -99,  17, -17, -19, -54, -84, -92,   2, -43, -88, -29,  96, -77, -84,  45, -16, -92, -99, -91;
/I:         I=-18; MI=0; MD=-45; IM=0; DM=-45;
/M: SY='N';  M= -84, -99,   7, -29, -45,  27, -36, -25, -44, -80, -90,  70, -96,  -9, -22,   7, -13, -66,  -5,  33; D=-18;
/I:         I=-18; DM=-45;
/M: SY='G';  M=  34, -91, -83, -86, -17,  56, -14, -85,  -8, -25, -51,  28, -91, -80,  -8,  -7, -78,   1, -94,  -3; D=-18;
/I:         I=-18; DM=-45;
/M: SY='P';  M= -78, -94, -80,  18, -90, -53, -86, -18,  29, -55, -78, -18,  57, -40,  10, -47,  43,  40,-101, -88;
/M: SY='I';  M= -79, -92,-105,-101, -71,-107,-104,  84, -97, -36,  12, -97, -96, -95, -99, -90, -75,  69, -99, -78;
/M: SY='P';  M= -51,-103, -85, -78,  -3, -88,  -8, -12, -23, -56, -82,  13, 106, -38, -48, -13, -77, -34, -92,  13;
/M: SY='Y';  M= -92,-101, -92, -95,  34, -99, -60, -75, -87, -45, -69, -93,-104, -83, -84, -87, -86, -80, -49, 131;
/M: SY='Y';  M= -42,  14,  -7,  15,  -9, -95, -81, -15, -45, -48,  17, -49, -92,  -5,   1, -23,  22,  52, -88,  53;
/M: SY='F';  M= -89, -94,-103,-101,  79,-104, -88,  61, -96,  28, -29, -36,-101, -96, -96, -93, -83, -26, -74,  37;
/M: SY='D';  M=  25, -93,  64,   5, -91,  12,  27, -95, -49, -66, -89, -68, -21, -74, -83,  43, -21, -90,  11,  14;
/M: SY='D';  M= -52, -99,  47,  23,-104,  29, -84,-104, -79,-104, -97,  11,  19, -77, -17,  39,   4, -99,-108, -49;
/I:         I=-24; MD=-61;
/M: SY='S';  M= -42,-100, -20, -14,-105,   1,  16, -66, -10,-104, -95,  47, -95,  38, -83,  50, -11,-100,   0, -93; D=-24;
/I:         I=-24; MI=0; MD=-61; IM=0; DM=-61;
/M: SY='Y';  M= -65,-107,-113,-110,  54,-115,  -4, -10,-107,  28, -31,-109,-116,-104,-104,-104, -97, -36, -81,  69; D=-24;
/I:         I=-24; DM=-61;
/M: SY='D';  M= -33, -95,  49,  15,-101, -36, -83, -97, -79, -66, -94,  20,   3, -77, -44,  46,  48, -92,-112, -94;
/M: SY='S';  M= -10, -97, -10,  10,   5,  11, -85, -44, -42, -15, -16,  17,  12,  -4, -37,  28,   9, -88, -99, -24;
/I:         I=-30; MD=-77;
/M: SY='N';  M= -11, -97, -19,   0, -43, -35, -32, -48, -18, -11, -84,  36, -53,   0,   7,  13,  27, -34, -99,  20; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='Q';  M=   7, -99,  -1,  33, -16, -57,  32, -16, -23, -88, -13, -17, -92,  49, -81,   6, -26,  -6,  38, -32;
/I:         I=-30; MD=-77;
/M: SY='R';  M= -89,-105, -88, -75, -93, -99, -81, -15,  51, -46, -83, -82, -41,  45,  67, -43, -48, -16, -96,  12; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='Q';  M=  26, -97, -37,  31,-104,  -4, -37,-101,  17,-100, -91,  14, -90,  35,   1,  31, -25, -94,-104, -93;
/M: SY='M';  M=   1, -95,  -1, -44, -85, -56, -90,  15,   2,  23,  31, -21, -96,   5, -44, -11,  13,   7,-103, -86;
/M: SY='I';  M= -58, -98,-110,-106,  37,-111,-104,  77,-102,   4,   9,-102,-102,-101,-104, -97, -83,  32, -94, -74;
/I:         I=-14; MI=0; MD=-35; IM=0; DM=-35;
/M: SY='R';  M=  -5, -99, -87,  13, -87, -98, -85, -35,  32,  35, -38, -22, -97, -75,  53, -48, -48, -33,-100, -87;
/M: SY='R';  M= -12, -99,   1,  12, -14, -40, -35, -97,  24, -36, -88,  15, -93,  27,  36,  29, -41, -94, -99, -17;
/M: SY='A';  M=  89, -87, -92, -86,-101,  -4, -94, -91, -88, -93, -87, -85, -92, -84, -93,  -7, -77, -50,-101, -96;
/M: SY='M';  M= -89, -96,-110,-103,  37,-107, -90,  48, -97,   3, 108, -99,-100, -93, -97, -97, -85,  -8, -93, -71;
/M: SY='R';  M=  17,-101,  14,  42,-102, -59,   3,-101, -31, -66, -90,  20, -91,  33,  49, -26, -45, -96,-104, -36;
/M: SY='H';  M= -19,-100, -83,  36,  39, -98,  79, -33, -13, -26,  35, -83, -95, -41, -37, -35, -31, -86, -89,  37;
/M: SY='W';  M= -96,-108,-113,-105,  40,-106, -98,  54, -99, -16, -74,-106,-104, -98, -74,-100, -94, -48, 124,  54;
/M: SY='E';  M=  10,-100, -70,  71,-101, -90,  32,-102, -22, -98, -28, -18, -87,  12,  10,  29, -80, -96,-103, -30;
/M: SY='N';  M= -42, -98,  29,   9,-101, -58, -78, -58,  15, -34, -90,  62, -92,  23,   9,  26, -17, -95,-109, -92;
/M: SY='H';  M= -87, -99, -77, -14, -24, -91,  75, -36,  38, -49, -84,  57, -95,   2, -10, -17, -29,  -6,  -1, -36;
/M: SY='T';  M= -76, -86, -82, -85, -93, -92, -92, -84, -82, -89, -85, -72, -85, -86, -90,   6, 108, -51,-113, -91;
/M: SY='C';  M= -85, 148,-105,-105, -96,-101,-105,-103,-101, -94, -94, -91,-116,-108,-108, -35, -85, -91,-126,-107;
/M: SY='I';  M= -57, -97,-110,-105, -19,-112,-107,  75,-102,  17, -62,-103,-102,-100,-104, -96, -82,  51,-100, -81;
/M: SY='R';  M= -56,-101,  -2, -26,-100, -95, -29, -51,  52, -68, -89,   6, -93, -70,  71, -34,  29, -94,-104, -89;
/M: SY='F';  M=-100, -97,-113,-108, 116,-108, -94, -46,-104, -45, -75,-102,-111,-114,-101, -99, -93, -78,  17, -45;
/M: SY='V';  M= -82, -98, -80,  34, -94, -96,   6, -26,  38, -67, -26,   2, -92,  -2,   8,   8, -40,  43,-106, -89;
/I:         I=-22; MI=0; MD=-57; IM=0; DM=-57;
/M: SY='P';  M= -44,-106, -75,  55,-101, -94, -82, -98, -17, -49, -90,   1,  79,   1,  28, -49, -22, -97,-101, -25;
/M: SY='R';  M= -40,-101,  21, -12, -92, -56, -77, -98,  13, -73, -89,  48, -43, -71,  70, -19, -82, -39,  26,  15;
/M: SY='T';  M= -40,  13,  -8,   0, -44,  -1, -41, -95, -44, -96, -90,  14,  23,  24, -24,  24,  61, -90,-106, -91;
/M: SY='N';  M= -12, -94,  25, -15, -41,   8, -80, -97, -79, -99, -92,  61,   2, -15, -47,  25,  38, -93,-105, -12;
/I:         I=-19; MD=-47;
/M: SY='E';  M=  22, -99, -12,  59, -63, -23,  35, -25, -33, -69, -20, -37, -88,  36, -81,   1, -40, -28,-104, -89; D=-19;
/I:         I=-19; MI=0; MD=-47; IM=0; DM=-47;
/M: SY='W';  M= -39, -99, -16,  12, -53, -16,  -8, -21,  25, -54, -86,   7,  11, -20,  25,  11,  12, -32,  31, -12;
/M: SY='D';  M= -33, -98,  73, -12,-100, -34,  15, -23, -79, -96, -21,  58, -39,  -7, -85,   2, -14, -22,-115, -91;
/M: SY='Y';  M= -10,-103, -92, -89,  11, -62,   0, -87, -41, -82, -78, -89,-103, -28,  46, -50, -88, -88, -65, 108;
/M: SY='I';  M= -53, -96,-108,-102, -71,-110,-100,  68,-100,  43,  11,-102,-102, -40,-100, -96, -82,  36, -98, -33;
/M: SY='R';  M= -84, -98, -29,  21,   2, -95, -18, -10,  18, -41, -81,   9, -94,   9,  36,  11, -18,  14, -20,   2;
/M: SY='F';  M= -90, -97,-108,-105,  73,-108, -97,  69,-100, -21,   6, -99,-102,-101,-101, -26, -84,  11, -83,  -3;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='F';  M= -84, -96,  -5, -53,  48, -25,  28, -18,  -8, -65, -35,  -2, -96,  21, -17, -22,  28,  25, -93,   0;
/I:         I=-26; MD=-65;
/M: SY='Y';  M= -84,-101,  11, -30, -91, -22, -22, -96,  32, -58, -90,   3,  15,   5,  -2,  36, -10, -41, -96,  38; D=-26;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='G';  M= -25, -97,  14, -49, -41,  58, -90, -44, -21,   2, -17, -19, -20, -46,  -9, -41,  -6,  -7,-101, -91;
/I:         I=-21; MD=-53;
/M: SY='D';  M= -49, -99,  54,  10, -14,   0, -81, -43, -14, -61, -92,  35, -18,  11, -56,  19,   0, -94,   6, -26; D=-21;
/I:         I=-21; MD=-53;
/M: SY='G';  M= -43,-102, -91, -96,   3,  78,   5,-107, -21, -63, -95, -79, -96, -89,  -4,   3, -47,-103, -99, -92; D=-21;
/I:         I=-21; MD=-53;
/M: SY='C';  M= -86, 149,-106,-106, -97,-102,-106,-103,-102, -94, -94, -92,-117,-110,-109, -89, -86, -91,-126,-107; D=-21;
/I:         I=-21; MD=-53;
/M: SY='W';  M= -15,-105, -97, -94,  40,  12, -81, -91, -55, -87, -85, -37,-102,  -6, -10,  -7, -90, -93, 100,  84; D=-21;
/I:         I=-28; MD=-71;
/M: SY='C';  M=-108, 108,-128,-128,-118,-123,-128,-125,-124,-116,-116,-114,-139,-131,-130,-110,-108,-112,-148,-129; D=-28;
/I:         I=-28; MI=-71; MD=-71; IM=-71; DM=-71;
/M: SY='C';  M=-108, 108,-128,-128,-118,-123,-128,-125,-124,-116,-116,-114,-139,-131,-130,-110,-108,-112,-148,-129; D=-28;
/I:         I=-28; DM=-71;
/M: SY='S';  M=  12, -86, -78, -38, -96, -72, -82, -93, -79, -98, -91,  -5, -86, -72, -84,  99, -60, -50,-104, -89;
/M: SY='Y';  M= -16, -96,  13,  -7,   2, -68,   1, -83, -79, -28,  36,  13,  -6, -45,   2,   1,  12, -84, -80,  78;
/M: SY='V';  M= -80, -93,-105,-101, -36,-108,-102,  61, -98, -11,   1, -99,-100, -97, -99, -91, -42,  76, -99,  -1;
/M: SY='G';  M= -72, -99, -87, -97,-105,  99, -93,-112, -91,-108, -97, -73,  -7, -89, -99, -43, -89,-106, -96,-100;
/M: SY='R';  M= -21,-101, -27, -75, -88, -28, -76, -94,  38, -89,  43, -30, -94, -17,  85, -81, -85, -92,  23,  25;
/M: SY='Q';  M= -18, -95, -20, -79,  -8, -90,  19,   5, -35, -42, -37,  28,   2,  49,   6,   4,   5,  28,-100, -32;
/I:         I=-17; MD=-42;
/M: SY='H';  M= -22,-119,-107, -57,   7,  25,  33,-118, -39,-115,-110, -39,  -8, -23, -72,   4,-103, -63,-118,-102; D=-17;
/I:         I=-17; MI=0; MD=-42; IM=0; DM=-42;
/M: SY='G';  M= -56,-100,  -3, -22,-102,  74, -88, -55, -44, -64, -24,  28, -16, -10, -19, -76, -55, -19,-103, -97; D=-17;
/I:         I=-17; DM=-42;
/M: SY='G';  M= -17, -98, -22,   1, -25,  78, -88, -50, -83,-101, -93, -18,  17, -82, -14,  -1, -41, -97, -97, -94;
/I:         I=-30; MD=-77;
/M: SY='P';  M=  11, -99, -83,  11, -95, -93, -13, -45,  35, -58, -18, -14,  45,   0,  28, -51, -24,  11,-101, -33; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='Q';  M= -81,-103, -75, -16,-107, -18, -72, -93, -65, -92, -81,  22, -89, 120, -66, -71, -82, -17, -97, -85;
/M: SY='P';  M= -17, -98,  15,  34, -57,   4, -14, -28, -47, -19, -22, -21,  48,   4, -14, -33,   7,  -4,-101, -28;
/M: SY='I';  M= -84, -93,-104,-100, -24,-107, -95,  53, -98,  49, -58, -39,-102, -95, -98, -93, -44,  49, -93,  15;
/M: SY='S';  M= -68, -89, -81, -55, -87, -78, -81, -43, -32, -91, -21, -35, -35, -74, -45,  93, -10,  -6,   2,  16;
/M: SY='I';  M= -88, -95,-106, -49,  24,-109, -95,  65, -99,  56,  34,-101,-101, -94, -99, -97, -83, -14, -91, -72;
/M: SY='G';  M=   2, -74,  15,   6, -75,  72, -62, -78, -35, -47, -15,  10,   0, -13, -67,   2, -16, -73, -75,  -2;
/I:         I=-21; MD=-53;
/M: SY='D';  M= -13, -75,  28,   4,  -2, -68, -59, -68,  22, -31, -64,   3,  19, -30,  21,  22,  24, -28,   4,  25; D=-21;
/I:         I=-21; MI=0; MD=-53; IM=0; DM=-53;
/M: SY='G';  M= -35, -74,  -5,   3, -78,  68, -60, -81, -42, -81, -72,  58, -29,   2, -65,  22,  -8, -77,  41, -70;
/M: SY='C';  M= -61, 152, -80, -80, -71, -76, -80, -77, -76, -69, -69, -66, -90, -84, -83, -62, -13, -65,-101, -81;
/M: SY='D';  M=   1, -74,  49,  27,  -5, -22, -62,  29, -34,   0,  37, -58, -30, -58, -30, -58,  15, -15,   5,   8;
/M: SY='Y';  M= -37, -75,  25,  -3, -24, -43, -15, -21,  23, -32, -11,  14, -69,  28,  33,  24,   0, -24,  10,  38;
/I:         I=-24; MD=-61;
/M: SY='F';  M= -27, -74, -32, -13,  70, -30,  28,   9,  19,  -6,  16, -12,  -8, -64, -62, -43, -16, -11, -60,  24; D=-24;
/I:         I=-24; MI=0; MD=-61; IM=0; DM=-61;
/M: SY='G';  M=   9, -97, -26, -63,   0,  90, -90,-104, -90,-100, -93, -49, -91, -88, -97, -72, -88, -98, -91,  -5;
/M: SY='T';  M= -51, -90, -92, -92, -81, -96, -97,  63, -88, -69, -70, -82, -90, -88, -47,  20,  68,  32,-104, -84;
/M: SY='I';  M=  38, -93,-100, -94, -79, -96,-101,  76, -93, -64, -65, -93, -94,  -3, -96, -82, -21,  43,-100, -83;
/I:         I=-30; MD=-77;
/M: SY='V';  M=  19, -24, -94, -11, -82, -95, -93,  33, -86,   2,  18, -90, -95,  19, -16,  -7, -24,  45,   0, -84; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='H';  M= -30,-102, -76, -76, -90, -92, 146,-107, -80, -91, -76, -65, -92, -70, -75, -43, -89,-105,-124, -60;
/M: SY='E';  M= -83,-103, -54, 109, -14, -99, -76,-105, -64, -97, -94, -80, -78, -57, -74, -79, -83, -98,-100, -92;
/M: SY='L';  M= -86, -93,-103, -96,  13,-106, -93,  43, -96,  63,  17, -97,-100,  -4, -95, -92,   7,  -4, -93, -74;
/M: SY='M';  M=   0, -93, -44, -92, -38,  51, -84, -19, -88,  -5, 100,   9, -93, -83, -91, -11, -81, -76, -97, -83;
/M: SY='H';  M= -92,-103, -76, -76, -87, -93, 146,-107, -81, -90, -76, -66, -93, -70, -75, -81, -90,-107,-118,   5;
/M: SY='A';  M=  71, -85, -89, -85, -92, -51, -92, -26, -85, -83, -80, -81, -90, -82, -90,  43,   6,  28,-102, -90;
/M: SY='L';  M= -86, -92,-107,-100, -66,-109, -95,  42,-100,  72,   2,-103,-103, -94, -98, -97, -82,  26, -96, -77;
/M: SY='G';  M= -71, -99, -87, -98,-105, 102, -93,-113, -92,-108, -98, -72, -90, -89, -99, -71, -90,-106, -96,-100;
/M: SY='F';  M= -93, -94,-108,-102, 102,-106, -91,  13, -95,  10, -27, -99,-105,-102,  -8, -95, -86,   1, -72, -51;
/M: SY='W';  M= -34,-103, -29, -14,  52, -97,   2,  -9, -89, -23,  -3, -11,-100, -42, -90, -55, -89, -83, 118,  71;
/M: SY='H';  M= -92,-103, -75, -76, -90, -93, 148,-108, -80, -91, -76, -65, -92, -69, -74, -81, -90,-108,-126, -59;
/M: SY='E';  M= -43,-100, -58,  99,-104, -48, -77,-102, -66, -97, -92, -77, -79,  25, -75, -41,  25, -94,-102, -94;
/M: SY='H';  M= -87,-105, -76, -66, -98, -92, 124,-104, -71, -92, -77, -68, -91,  95, -69, -76, -87,-104,-109, -68;
/M: SY='S';  M=   9,   0, -79, -26, -94, -80, -81, -87, -77, -34,   2,   2, -88,  47, -82,  69,  41, -48,-103, -88;
/M: SY='R';  M= -89,-105, -86, -74, -98, -99, -74,-105, -46, -97, -86, -78, -97, -62, 115, -45, -87, -98, -98, -85;
/M: SY='P';  M=   7, -97,  -9, -46,  -2, -38, -85, -89, -83, -42,  -5, -40,  79, -17, -90,  39,   2, -88,  27,   3;
/M: SY='D';  M= -90,-103, 117, -33,-110, -86, -75,-108, -77,-107,-105, -25, -89, -76, -85, -78, -79,-105,-125, -93;
/M: SY='R';  M= -33,-105, -86, -73, -98, -98, -75,-104, -47, -97, -86, -79, -97, -27, 114, -82, -87, -97, -98, -85;
/M: SY='D';  M= -90,-103, 115, -21,-109, -87, -75,-107, -77, -71,-103, -15, -89, -39, -85, -78, -79,-104,-124, -92;
/M: SY='N';  M= -51, -98,  55,  34,-104, -55, -73,-102,  -6,-100, -41,  60, -89,  48,  22,   4, -77, -99,-107, -90;
/M: SY='Y';  M= -92,-101, -92, -92,  55, -98,  63, -81, -86, -76, -74, -87,-103, -83, -22, -14, -86, -85, -60, 111;
/M: SY='I';  M= -82, -93,-107,-102, -71,-109,-102,  67, -99,  35, -11,-101,-100, -97,-100, -94, -79,  61,-100, -80;
/M: SY='N';  M= -52, -94,  -1, -34, -90, -41, -27,  33,  29, -84, -80,  37, -90, -19,   4,  28,  34, -19,-102, -32;
/M: SY='I';  M= -82, -95,-106,-103,  -8, -39,-106,  84, -99, -30, -61, -98, -98, -98,-102, -92, -79,  59, -98, -78;
/M: SY='N';  M= -84, -95,  35, -32, -53, -88,  44, -19, -35,  -8,   4,  67, -94, -28, -15, -13,  -5,  -4,  22,  13;
/M: SY='W';  M= -15,-101, -93, -17, -21, -93, -35, -83,  21, -16, -81, -89, -37, -80,   2,  -3,   4, -16, 121,  50;
/M: SY='D';  M= -36, -96,  47,  34,-101, -60, -30, -97,   6, -97, -90,  42, -87,  46, -19,  18,  22, -53,-107, -90;
/M: SY='N';  M= -85, -93,   7, -30, -28, -80,   7, -93, -24, -55, -88, 104, -36, -25,   1, -52, -74, -32,  -8, -14;
/M: SY='I';  M= -28, -97, -14, -98, -72,-104, -19,  83, -96, -61, -20, -94, -97, -93, -99, -42, -79,  44,   7,  20;
/M: SY='Q';  M= -55, -99,  37,  22, -91, -92, -79,  21, -29,  -4,  18,  28,  -2,  57,   0, -24, -47, -57,-102, -86;
/M: SY='P';  M= -11,-100,   4,   9, -20, -88, -83, -93,  18, -26, -87,  11,  78, -11,   7,  -3, -13, -92,-100, -90;
/M: SY='G';  M= -22, -97,  26, -10,-103,  67, -83,-104, -25,-102, -28,  16, -89,  14,   4,  16, -44, -99,-101, -94;
/M: SY='Q';  M=   5, -40,   1, -78,  -9, -90, -24, -11, -51, -23,  54, -38,   2,  54, -13,  11,  -5, -79, -87,  48;
/M: SY='E';  M= -39, -98, -20,  56, -41, -95, -78, -37,  -9, -10,  17, -15, -89,   8,  18, -42,  11, -24,  31,  40;
/I:         I=-12; MD=-30;
/M: SY='H';  M= -49,-102,  17, -48,  21,   2,  67, -14, -56, -89, -84, -37,  28, -12,  12,   6, -45, -91, -90,  48; D=-12;
/I:         I=-12; MD=-30;
/M: SY='N';  M= -25, -96,  27, -48,-101, -80, -71, -99, -71,-101, -39,  95, -93,  60, -20, -19, -44, -99,  31, -89; D=-12;
/I:         I=-12; MD=-30;
/M: SY='F';  M= -38, -96,-108,-105, 111, -21, -90, -75,-101, -47, -76, -98,-107,-108, -99, -94, -43, -79, -67,  15; D=-12;
/I:         I=-12; MD=-30;
/M: SY='E';  M=  20, -96,  33,  44, -92, -37, -82, -23, -18,  -6,  43,  17, -90,  -9,  -8, -79, -45, -20,-104, -88; D=-12;
/I:         I=-12; MD=-30;
/M: SY='K';  M= -56,-102, -86, -75, -98, -98, -88,   0,  84, -35, -84, -34, -32,  18, -45, -84, -11,  -9,-101, -91; D=-12;
/I:         I=-12; MD=-30;
/M: SY='Y';  M= -59,-101, -29,   2,   3,-103, -29, -31, -85,  21,  22, -20,-102, -37,  15, -22, -45,   5, -87,  60; D=-12;
/I:         I=-12; MD=-30;
/M: SY='D';  M= -17, -99,  48,  -8, -47, -28, -85,-100,  -2, -53, -95,  24, -22, -44, -27,  37,  14, -96,  32, -92; D=-12;
/I:         I=-12; MD=-30;
/M: SY='P';  M= -12,-104,  16,  28, -99, -58, -40, -43, -17, -33, -92,  -1,  49, -26, -55,  10,  -8, -51,  44, -43; D=-12;
/I:         I=-12; MD=-30;
/M: SY='N';  M= -23,-106,  -4, -11,-101, -17, -34,-105,  10, -69, -17,  29, -36, -24,  -8,  28, -42, -72,  15,   6; D=-12;
/I:         I=-12; MD=-30;
/M: SY='E';  M=-105,-118,  -9,  28, -51, -66, -27, -51, -63,  -1, -48, -24,-111,   4, -67, -41,  12, -51,-124,-106; D=-12;
/I:         I=-12; MI=0; MD=-30; IM=0; DM=-30;
/M: SY='M';  M= -24,-103, -43, -96, -36,-102, -24,  17, -23, -41,  28,   7,-105,   5, -95,  11, -54,  26,   5,  18; D=-12;
/I:         I=-12; DM=-30;
/M: SY='T';  M= -78, -92,  47,  -7, -46, -85, -11, -90, -76, -93, -88,  30, -87,  17, -50,  37,  65, -35,  -1, -14;
/M: SY='T';  M= -26, -93,   9,   4, -84, -87,   6,  -9, -76, -26, -82,  36, -31, -76,  11,  31,  47, -82,   7,  31;
/M: SY='Y';  M= -53, -95, -91, -91, -17, -32, -77, -33, -85,  38,  41,  29, -53, -18, -13, -58,  -7, -21,   8,  73;
/M: SY='G';  M= -51, -97, -17, -48, -82,  59,  -2,  12, -86,  -2,   4,  35, -40, -84, -39, -28, -82, -26, -93,  32;
/M: SY='V';  M= -49, -93, -43,  21, -86,  31, -91, -31, -85,  -2,  -5, -84, -92,  20, -89, -78,  30,  54,-103, -87;
/M: SY='P';  M= -27,-105,   5,  -5,-103, -16, -24, -53,  -3, -74, -90, -51, 104, -82, -68, -71,   6, -95,-103, -98;
/M: SY='Y';  M= -95,-102, -96, -98,  62,-101, -64, -77, -90, -72, -72, -95,-106, -88, -87, -90, -88, -82, -52, 123;
/M: SY='D';  M= -28,-102, 110,  30,-109, -87, -76,-107, -75,-105,-103, -61, -87, -37, -84, -77, -80,-102,-120, -93;
/M: SY='Y';  M= -37,-100, -94, -95,  28,-100,  24, -25, -90, -18, -70, -93,-103, -86, -87, -88, -46, -14, -59, 117;
/M: SY='G';  M= -35, -97,  41,  -7,-100,  76, -84,-106, -24,-104, -96,   9, -89, -80, -89,   1, -38,-101, -99, -10;
/M: SY='S';  M= -63, -86, -78, -79, -96, -71, -81, -96, -79,-100, -93, -66, -86, -71, -83, 108, -58, -88,-105, -88;
/M: SY='I';  M= -81, -94,-105,-102, -37,-109,-106,  79, -98, -20, -61, -97, -98, -98,-101, -90,  -4,  64,-101, -80;
/M: SY='M';  M= -83, -91,-106, -95, -73, -98, -76, -57, -88, -26, 145, -92, -93, -80, -86, -93, -82, -65, -96, -72;
/M: SY='H';  M= -90,-101, -81, -78, -85, -96, 133,  -2, -82,  -7,  39, -71, -93,  21, -77, -83, -88, -88,-114, -64;
/M: SY='Y';  M= -94,-104, -93, -96, -41,-100, -59, -79, -88, -75, -72, -94,-106, -83, -85, -88, -88, -84, -49, 134;
/M: SY='G';  M=   3, -96,  16, -46, -96,  57,  50,-100, -31, -98, -90,  17, -27, -46,  -2,  10, -18, -53,-100,  -5;
/M: SY='P';  M=  25, -95, -37, -12, -20, -10, -82, -93,   0, -52, -87,  10,  46, -33,  30,  38, -52, -53, -98, -32;
/M: SY='Y';  M= -55, -94,  38, -34, -14, -55, -18, -85,  -4, -14, -81,  41, -92, -28, -21, -10,  44, -46, -89,  60;
/M: SY='A';  M=  60,  -4,   2,   2, -96, -29, -36, -45, -80, -64, -85,   2, -29, -11, -86,  21,  31, -45,-103, -91;
/M: SY='F';  M= -27, -94, -35, -97, 103,  -7,  14, -75, -95, -28, -75, -36,-103, -99, -94, -24, -86, -50, -70,  21;
/I:         I=-8; MD=-20;
/M: SY='S';  M=  24, -91, -82, -18, -32,  15, -87, -97, -83, -99, -93,  -5, -91, -78, -46,  78, -22, -55,-104, -92; D=-8;
/I:         I=-8; MI=0; MD=-20; IM=0; DM=-20;
/M: SY='R';  M= -89,-105, -92, -36, -98,-102, -90,  -8,  45, -63, -87, -38,-100,   4,  53,   2, -40,  20,-106, -40; D=-8;
/I:         I=-8; DM=-20;
/M: SY='N';  M= -61,-102,  63, -78, -69,  14, -81,-107, -41,-108,-101,  71, -39, -83, -57,  -9, -24,-105, -11,   1; D=-8;
/I:         I=-8; DM=-20;
/M: SY='G';  M= -34,-103,  -9, -33, -97,  49, -93,  -6, -27, -96, -25, -83,  20,   1, -54,   0,   7, -35,  20,  -6; D=-8;
/I:         I=-8; MI=0; MD=-20; IM=0; DM=-20;
/M: SY='N';  M= -45,-121, -18,-109, -10, -22, -26,-115, -42,-118,-114,  12,-120,-107, -35,   9,  -5, -36, -18, -19; D=-8;
/I:         I=-8; DM=-20;
/M: SY='K';  M= -60,-106, -25, -11, -11, -41, -94, -15,  28,  15, -27, -91, -38,  -3,   7,   7, -47, -42,-105, -49; D=-8;
/I:         I=-8; DM=-20;
/M: SY='P';  M= -26,-111,  31, -16, -25, -34, -91, -25,   0,-104, -97,  11,  72, -36, -46, -57, -88, -61,-107,  -9; D=-8;
/I:         I=-8; DM=-20;
/M: SY='T';  M= -80, -92, -88, -90, -95, -96, -96, -84, -41, -89,  10, -78, -90, -89, -93,  10,  97, -13,-115, -94; D=-8;
/I:         I=-8; DM=-20;
/M: SY='M';  M= -90,-101,-110,-103, -76,-110, -95,  72, -96,   2,  90,-100, -29, -93, -20, -98, -86, -15, -99, -26; D=-8;
/I:         I=-8; DM=-20;
/M: SY='T';  M= -36, -97, -39,  28, -35, -55, -94,  21, -54,   5, -18, -27, -95, -86, -48, -46,  39,  31,-104, -32; D=-8;
/I:         I=-8; DM=-20;
/M: SY='P';  M=  15,-103, -91, -83,-105, -91, -94, -95, -33,-101, -26, -89,  96, -88, -36, -45,  46, -92,-107,-101; D=-8;
/I:         I=-8; DM=-20;
/M: SY='K';  M= -93,-106, -94, -84, -53,-105, -90,   4,  68,   4, -82, -53,-101, -79,  30, -52, -89, -18, -98,  13; D=-8;
/I:         I=-8; MI=0; MD=-20; IM=0; DM=-20;
/M: SY='D';  M= -95,-109,  71,   7,-101,-100, -88,  15, -32, -96, -94,  15, -40,  10, -31, -89, -88,  -8,   6, -22; D=-8;
/I:         I=-8; DM=-20;
/M: SY='P';  M= -64, -21, -34, -18,-102, -93, -88, -95, -37, -58,  38,  33,  58, -33,   3,  30,  -3, -58,  -8, -97; D=-8;
/I:         I=-8; DM=-20;
/M: SY='E';  M= -39,-102,  15,  39, -57,  18,   3, -97,  23, -29, -91,  22, -13, -34, -10, -36, -28, -28,-107, -93; D=-8;
/I:         I=-8; DM=-20;
/M: SY='Y';  M= -28,-102, -29, -93,  47, -54, -81, -41, -60, -27,  34, -56,  19,  -1, -92,   1, -86, -27, -77,  77; D=-8;
/I:         I=-8; DM=-20;
/M: SY='Q';  M= -19,-101, -30,   8, -41,   3, -83, -33,   8, -86, -87,  29, -51,  64, -26, -28,  -4,  -3,-102, -27; D=-8;
/I:         I=-8; DM=-20;
/M: SY='N';  M=  11, -99, -19, -47, -35, -59,  18, -61,  -6, -41, -12,  46, -27,  22,   8,   5, -25, -17,-107, -35; D=-8;
/I:         I=-8; DM=-20;
/M: SY='T';  M= -32, -97, -92, -62, -97,-101,-100, -10, -20, -68, -88, -84,  -7, -92, -28, -40,  86,  -8,-115, -96; D=-8;
/I:         I=-8; MI=0; MD=-20; IM=0; DM=-20;
/M: SY='M';  M= -89, -99,-109,-102, -21,-108, -95,  69, -98,  17,  94,-100,  -5, -93, -99, -98, -85, -30, -97, -78;
/M: SY='G';  M= -76,-103, -90, -53,-103,  93, -97, -69, -95,-108, -99, -78, -94, -92,-102, -45, -93, -61,  30, -44;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='Q';  M= -59,-103, -24, -67,-107, -55, -17, -48, -43, -63, -86,  18, -92, 105, -73,  32, -25, -97,-103, -88;
/M: SY='R';  M=  -7,-104, -47, -38, -47, -52, -81, -98, -15, -22, -24, -38, -39, -25,  94, -84, -52, -95,-101, -88;
/M: SY='R';  M= -14,-101,  22,   2, -20, -67, -86,  13,   3, -39,  27, -29, -55, -15,  44, -50, -20, -16,   7, -14;
/I:         I=-26; MD=-65;
/M: SY='D';  M= -25,-115,  37, -51,-115,  23,   9,-119,  23,-116,-107, -34,-105,  -7,   8, -60, -58,-114,-116, -33; D=-26;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='M';  M= -36, -97,-107, -99,  45,-105, -95, -62, -99,  45,  50,-103,  37, -98,-100, -96, -86,  31, -93, -74;
/M: SY='S';  M=  -2, -89, -83, -84, -98, -34, -87, -95, -84, -71, -92, -34, -89, -78, -89,  87,  43, -87,-108, -92;
/M: SY='F';  M=   9, -98,   5,  -8,  82, -96, -88, -59, -31, -81, -84, -18,   2, -22, -19, -41,  -4, -85, -83,  -7;
/M: SY='Y';  M= -23, -99, -93, -94, -32,  13, -83,   7, -31,  10, -31,   1,-100, -34, -91,   8,  -8, -26,  -6,  70;
/M: SY='D';  M= -94,-107, 114, -57,-114, -90, -79,-112, -81,-110,-109, -36, -93, -80, -89, -81, -83,-109,-129, -96;
/M: SY='I';  M= -26, -99,-107,-103, -36,-108, -95,  69, -68,   5,  53,-100,-101, -95, -99, -62, -84,  21, -92,  36;
/M: SY='K';  M=   4, -98, -44,   8, -55, -96, -18, -11,  32,   0, -79, -46, -95, -33,  26, -10, -17,   2, -97,  15;
/M: SY='K';  M= -56,-101, -88, -78, -92, -27, -84, -13,  55,   3,  40,   0, -95,  42,  26, -83, -12, -45,-100, -87;
/M: SY='I';  M=  -7, -97,-108,-103, -76,-107,-102,  73,-100,  24,  42,-100,-101, -96,-102, -73, -33,  16,-101, -83;
/M: SY='N';  M= -88,  -3, -63, -82,-102, -78, -70,-101, -13, -79, -95, 116, -99, -75, -27, -72, -74,-103,-120, -97;
/M: SY='K';  M= -53, -99, -35, -14, -47, -97,  -2, -89,  56, -26, -10, -43, -92,  35,  28, -79,  39, -16,-103, -87;
/M: SY='M';  M=  13, -97,-103, -97,  -9,-101,  29,   7, -94,  48,  57, -97,-103, -89, -28, -92, -87, -70, -90,  40;
/M: SY='Y';  M= -97,-108, -96, -99, -24, -60, -63, -83, -91, -79, -76, -97,-109, -87, -89, -92, -91, -88, -53, 129;
/I:         I=-26; MD=-65;
/M: SY='N';  M= -93,-109, -82, -10,-114,  17, -20,-114,  29,-114,-103,  61,-102,  28, -21, -16, -53,-112,-116,-103; D=-26;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='C';  M= -87, 147,-106,-106, -97,-102,-106,-104,-102, -95, -95, -93, -26,-110,-109, -90, -87, -92,-126,-108;
/M: SY='P';  M= -47,-100, -36, -47,-101,  -4, -21, -98,  20,-102, -93,  22,  50, -10, -29,  43,   5, -41,   6, -35;
/I:         E1=0; IE=-255; DE=-255;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2019_10 which contains 561'356 sequence entries.


Total number of hits 87 in 87 different sequences
Number of true positive hits 87 in 87 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] Peptidase M12A
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
87 sequences

ASTA_ASTAS  (P07584    ), ASTL_CHICK  (P0DJJ2    ), ASTL_COTJA  (P42662    ), 
ASTL_HUMAN  (Q6HA08    ), ASTL_MOUSE  (Q6HA09    ), BMP1_HUMAN  (P13497    ), 
BMP1_MOUSE  (P98063    ), BMP1_XENLA  (P98070    ), BMPH_STRPU  (P98069    ), 
BP10_PARLI  (P42674    ), COG4_CHIOP  (P34156    ), FLVS_ELIME  (Q47899    ), 
HCE1_ORYLA  (P31580    ), HCE2_ORYLA  (P31581    ), LCE_ORYLA   (P31579    ), 
MEP1A_HUMAN (Q16819    ), MEP1A_MOUSE (P28825    ), MEP1A_RAT   (Q64230    ), 
MEP1B_HUMAN (Q16820    ), MEP1B_MOUSE (Q61847    ), MEP1B_RAT   (P28826    ), 
NAS10_CAEEL (Q21388    ), NAS11_CAEEL (Q21432    ), NAS12_CAEEL (Q9XTD6    ), 
NAS13_CAEEL (Q20191    ), NAS14_CAEEL (Q19269    ), NAS15_CAEEL (P55115    ), 
NAS16_CAEEL (Q21180    ), NAS17_CAEEL (Q21178    ), NAS18_CAEEL (Q21179    ), 
NAS19_CAEEL (Q21181    ), NAS1_CAEEL  (O62243    ), NAS20_CAEEL (Q22396    ), 
NAS21_CAEEL (Q22401    ), NAS22_CAEEL (Q22398    ), NAS23_CAEEL (Q7Z0M7    ), 
NAS24_CAEEL (Q93542    ), NAS25_CAEEL (Q20459    ), NAS26_CAEEL (Q22710    ), 
NAS27_CAEEL (O17264    ), NAS28_CAEEL (P98061    ), NAS29_CAEEL (Q20958    ), 
NAS2_CAEEL  (Q9N5R0    ), NAS30_CAEEL (Q9N2V2    ), NAS31_CAEEL (Q7JLI1    ), 
NAS32_CAEEL (O16977    ), NAS33_CAEEL (P55114    ), NAS34_CAEEL (Q21059    ), 
NAS35_BRUMA (A8Q2D1    ), NAS35_CAEEL (P98060    ), NAS35_HAECO (D5FM34    ), 
NAS35_TELCI (A0A0C5PRQ1), NAS36_BRUMA (D5FM38    ), NAS36_CAEBR (Q61EX6    ), 
NAS36_CAEEL (Q18206    ), NAS36_HAECO (D5FM37    ), NAS37_CAEEL (Q93243    ), 
NAS38_CAEEL (Q20942    ), NAS39_CAEEL (Q20176    ), NAS3_CAEEL  (Q21252    ), 
NAS4_CAEEL  (P55112    ), NAS5_CAEEL  (P91828    ), NAS6_CAEEL  (Q9U3S9    ), 
NAS7_CAEEL  (P55113    ), NAS8_CAEEL  (Q18439    ), NAS8_STECR  (D2KBH9    ), 
NAS9_CAEEL  (P91137    ), PEP16_ARGAU (P84748    ), PEP18_ARGAU (P84749    ), 
SEMP1_DROME (Q9VJN9    ), SPAN_STRPU  (P98068    ), TLD_DROME   (P25723    ), 
TLL1_CHICK  (Q9DER7    ), TLL1_DANRE  (O57460    ), TLL1_HUMAN  (O43897    ), 
TLL1_MOUSE  (Q62381    ), TLL1_XENLA  (Q8JI28    ), TLL2_HUMAN  (Q9Y6L7    ), 
TLL2_MOUSE  (Q9WVM6    ), TLL2_XENLA  (O57382    ), UVS2_XENLA  (P42664    ), 
VMPA2_LOXIN (C9D7R2    ), VMPA3_LOXIN (C9D7R3    ), VMPA4_LOXLA (P0DM61    ), 
VMPA5_LOXGA (P0DM62    ), VMPA_LOXIN  (A0FKN6    ), VMP_NEMVE   (K7Z9Q9    )
» more

PDB
[Detailed view]
22 PDB

1AST; 1IAA; 1IAB; 1IAC; 1IAD; 1IAE; 1QJI; 1QJJ; 3EDG; 3EDH; 3EDI; 3LQ0; 3VTG; 4GWM; 4GWN; 6BSL; 6BSM; 6BTN; 6BTO; 6BTP; 6BTQ; 6HT9
» more

View entry in original PROSITE format
View entry in raw text format (no links)
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