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Entry: PS51874

General information about the entry

Entry name [info] PCV_3C_PRO
Accession [info] PS51874
Entry type [info] MATRIX
Date [info] 10-APR-2019 CREATED;
07-APR-2021 DATA UPDATE;
02-JUN-2021 INFO UPDATE.
PROSITE Doc. [info] PDOC51874
Associated ProRule [info] PRU01222

Name and characterization of the entry

Description [info] Picornavirales 3C/3C-like protease domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=200;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=195;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.8413713; R2=0.0100723; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=20654.7421875; R2=11.8387909; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1059; H_SCORE=33192; N_SCORE=12.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=463; H_SCORE=26136; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-28; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='G';  M=  28, -76,  33, -31, -78,  64, -63, -79, -23, -44, -70,  16, -13,  17, -67, -26, -61, -74, -78, -12;
/M: SY='P';  M=  37, -79, -70, -62, -72, -13, -69, -64, -66, -40,  13, -70,  97, -66, -74, -25, -59, -12, -75,  13;
/M: SY='A';  M=  28,  -2,   5,  23, -69, -28, -61, -62, -24, -40, -63,   5, -10,  20,   3,  25, -35,  16, -77,  20;
/M: SY='M';  M=  -2, -75,   9,  14,  36, -13,  -6, -26, -14,  -5,  55, -60, -71,   4,   8,  10,   1, -60,  30, -54;
/M: SY='D';  M= -59, -78,  67,  40, -83,  18,  28, -80, -26, -80, -74,   6, -16,  14, -60,  32, -57, -35, -89, -70;
/M: SY='F';  M= -37, -77,  -1,  10,  70, -78, -62, -20, -63,  23,   8, -67, -22,  63, -64, -66, -65, -26, -62,   0;
/M: SY='A';  M=  44, -72,  33,  33, -75,  12, -63, -12, -59, -19,  -8, -14, -68,  -4, -65,  32, -55, -62, -82, -70;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='E';  M= -25, -73,  -5,  38, -62, -74,  16, -27,   4,  25,  12,   2, -70, -28, -25,   0,  15,  14, -80,  -8;
/M: SY='S';  M=  25, -72,  -2,  25,  -6,  15,  11, -70, -25, -28,   2,  32, -69, -55, -63,  40, -55, -39,  19, -12;
/M: SY='M';  M= -64,   7, -77, -16, -52, -38,  27,  34, -26,  38,  40, -73, -31, -67, -29, -70, -61,  39, -75,  15;
/M: SY='M';  M=  37, -71, -21, -26, -21, -74, -70,  20, -69,  44,  55, -73, -18, -66, -26, -64, -60,   9, -76, -60;
/M: SY='K';  M= -16, -78, -14,  20, -73, -28,  26, -19,  55, -10, -60, -22,  -5,   8,  33, -18, -60,  -5, -80, -65;
/M: SY='K';  M= -24, -75, -18, -54, -23, -11,  27, -73,  54, -71,  31,  47, -70,   0,  37, -23,  19, -71, -80, -63;
/M: SY='N';  M= -40,  37, -53, -12, -31, -29,   8, -46, -57, -37,  51,  83, -73,  28, -62,  10, -14, -23,  28, -64;
/M: SY='L';  M= -15, -31, -73, -66, -59, -30, -10,  19,  11,  36,  27, -66, -74,  13, -12, -24,  26,  21, -79, -61;
/M: SY='C';  M=  22,  71, -76, -71, -54, -74, -67, -46, -67,   9, -21, -71, -12,  -8, -13, -12, -58,  46, -71,  52;
/M: SY='C';  M= -31,  58, -69, -62, -64, -30, -67,   7,   0,  -7, -56, -23,  15,  41,  19, -58,  32,  10,  24,   4;
/M: SY='I';  M=   1, -73, -78, -24,  18, -33, -70,  46, -72,  12,  41, -73, -76, -70, -74, -65,   6,  36, -68,  33;
/I:         I=-31; MD=-79;
/M: SY='T';  M=   3,  21, -10, -64, -27,  24, -65, -34, -10,  -8, -61,   5, -73,  12,  -3,   5,  28,  -1, -77,  13; D=-31;
/I:         I=-31; MD=-79;
/M: SY='T';  M= -63,   9,   9, -30,  23, -78, -68,  20, -69,  16,  40, -46, -75, -68, -73,  -7,  51,   8, -75,   9; D=-31;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='P';  M=   0, -76,  14,  31,  -9,   9, -63, -58, -16, -36,  -6, -13,  47, -55,   9,  21,   6, -35, -80, -68;
/M: SY='T';  M= -32, -74,   6,  -2, -72,   1, -59, -68,  43, -36, -12,  42, -68,  14,  -5, -27,  44, -20, -79,  -2;
/M: SY='G';  M=  -8,   7,  -1, -68, -82,  86, -70, -41,  -1, -81, -72, -10, -71, -21, -56, -52, -66, -34, -78, -76;
/M: SY='E';  M= -29,  13,  -2,  50, -75, -26,  43, -68,  15, -35, -64,  20, -69, -49,  31,   4, -29,  11, -85, -66;
/I:         I=-22; MD=-55;
/M: SY='M';  M= -73, -84, -84, -82,  18, -87,   5,  12, -38, -19,  41,  -1,   5, -78, -81,  -2,  -4,  23, -85, -11; D=-22;
/I:         I=-22; MI=0; MD=-55; IM=0; DM=-55;
/M: SY='F';  M= -11,  58, -83, -78,  63, -43, -73,  28, -75,  -6,  10, -40, -84,  18, -77, -69, -16,  -2, -67,   6; D=-22;
/I:         I=-22; DM=-55;
/M: SY='T';  M= -56,  11, -57, -58, -71, -64,  34, -67, -53, -70, -63,  40, -69,  36,  15,  48,  57,  -8, -84,  -7;
/M: SY='C';  M=  41,  82, -75, -73, -68,  34, -74,   6, -71, -34,  50, -64, -75, -69, -75, -37,  -1,   5, -82, -70;
/M: SY='L';  M= -26,  50, -76, -75, -10, -79, -70,  -2, -73,  59,  28,   7, -79, -71, -74, -65,  32,  -3,  -4, -58;
/M: SY='G';  M= -14, -78, -17, -68,  25,  61, -66, -65, -64,   5,  40, -61, -18,  27,  -3, -59, -67, -67,  42,  -9;
/M: SY='V';  M= -34, -72, -84, -79,  26, -85, -74,  32, -76,  14, -43, -79, -82, -76, -77, -70, -58,  72, -67,  44;
/M: SY='R';  M= -67,   1, -65, -57,   9, -12,  39, -73,  45, -35, -62, -60,  41,  -1,  52, -62, -24, -73, -66,  45;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='G';  M= -26, -77,  59, -57, -84,  69,  10, -86, -23, -85, -76,  17, -14, -60, -68,  16, -60, -81, -85, -74;
/M: SY='R';  M= -65, -79,  11, -54, -76,   4,  37, -81,  30, -78, -68,  33, -72, -30,  72, -56,  21, -77,  45, -63;
/M: SY='W';  M= -26,  -6, -68, -18,  12, -70, -65,  -2, -21, -16, -58, -19, -74, -17,  26,  45,  -6,  10,  77,  19;
/M: SY='F';  M=   8,  25, -83, -76,  56, -80, -72,   5, -75,  37,   9, -77, -82, -13, -75, -68, -61,  40, -67,   1;
/M: SY='M';  M=  10,  10, -83, -76, -12, -81, -73,  35, -73,  49,  49, -77, -80, -71, -18, -69, -60,  33, -76, -58;
/M: SY='M';  M=  12,  25, -81, -75, -13, -21, -71,  11, -73,  40,  73, -73, -78, -69, -74, -25, -22,  29, -77, -59;
/M: SY='P';  M= -63, -11, -63, -61, -72, -70,  26, -64, -62, -72, -65,  27,  92, -65, -71, -54,  57,   0, -82,   3;
/M: SY='R';  M= -11, -76, -62, -57, -68,  11, -49, -74,  35, -36, -64, -17, -71,  -9,  64,  10,  31, -69, -73,  25;
/M: SY='H';  M=-119,-130,-103,-103,-117,-120, 155,-136,-108,-118,-103, -92,-119, -97,-102,-108,-117,-135,-153, -86;
/I:         I=-20; MD=-51;
/M: SY='Q';  M= -12, -85, -78, -27,  34, -36, -71, -24, -69,  -7,  11, -73, -83,  68, -70, -21, -20,  -1, -76,  -4; D=-20;
/I:         I=-20; MD=-51;
/M: SY='A';  M=  47, -80, -89, -83,  46, -79, -81,  19, -82, -17,   0, -83, -86, -81, -83, -69, -69,   1,  21,   0; D=-20;
/I:         I=-20; MD=-51;
/M: SY='W';  M= -37,-101, -30,   8, -88, -47, -86, -84,  12,  14, -14, -86, -95,  20, -78, -36, -86, -86,  21, -86; D=-20;
/I:         I=-20; MI=0; MD=-51; IM=0; DM=-51;
/M: SY='A';  M=  58,  26, -17,   1,  24, -31, -66, -28, -31, -12,   2, -62, -72,  -2,  19,  -6, -30, -58, -74, -61;
/M: SY='E';  M=  13, -76,  22,  37, -18, -67,   7,  15,   7, -64,  27,  11, -17,  23, -25,  19, -56, -33, -80, -64;
/M: SY='P';  M= -66, -84,  11,  20, -22, -35, -69,   3,  25,  -8, -61, -66,  86, -60, -63, -65, -61,  -6,  23, -69;
/M: SY='G';  M=  -9, -77,  43,   1, -73,  49, -64, -19,   0, -39, -69,   5,   1, -59, -65,  -8,  11, -70,  38,  -5;
/M: SY='D';  M= -31,  -1,  44,  22, -72,   8,  -7, -75,   4, -35, -68,   7,  32, -18, -24,  10,  18, -72, -79,  20;
/I:         I=-38; MD=-97;
/M: SY='N';  M= -31, -75,  13,  35, -24, -34, -60, -49,  15, -77, -70,  47,  -2,   4, -19,  27,  35, -71, -85, -70; D=-38;
/I:         I=-38; MI=-97; MD=-97; IM=-97; DM=-97;
/M: SY='I';  M= -63, -75, -76, -16, -55, -83,   5,  52, -70,  29,  28, -71, -77, -14, -25,  -7,  10,  28, -79, -12; D=-38;
/I:         I=-38; DM=-97;
/M: SY='M';  M= -64, -76, -71, -20, -56, -39,  31,  23, -63,  -9,  53,   3, -76,  -8,   6, -32,  18,  28,  27,  34; D=-38;
/I:         I=-38; DM=-97;
/M: SY='V';  M= -29,   4, -77,  -6, -15, -34,   4,  46, -72,   0,  37, -73, -77, -23, -73, -68, -59,  58, -75,  19;
/M: SY='N';  M= -31,   2,  30,  27,  11, -31,   1,  -3,  -2, -34, -61,  30, -72,   2,   4,  -9, -59,   5, -73,  29;
/M: SY='G';  M= -15,   6,  -8, -69,  30,  37,  28,  20, -62, -10, -57,  25, -76, -64,  17, -23, -63, -60, -68,  33;
/M: SY='Y';  M=  -7, -75,  -3, -10,  25, -74, -25,  -6,  21, -19, -55, -62, -73,  29, -15,  -1,  -2,  28, -67,  42;
/M: SY='Q';  M=  23,  10,  -9,   7, -26, -29,  -8, -64, -18, -37, -13,  -6, -37,  37, -61,  30,  36,  -5, -79, -10;
/M: SY='T';  M= -20, -73,  16, -63,   9,   1,  12,  13, -63, -49,  -3,  23,   8, -19, -16, -30,  44,  28, -82, -61;
/M: SY='N';  M=  -9, -60, -25,   0, -77,  43, -61, -29,   8, -72,  16,  46,   3, -27,  20,  -1,  -6, -20, -82, -71;
/M: SY='V';  M= -26,  -1,   6,  10, -66,  14, -66,   6,  23, -47, -28, -58, -71, -58,  11,   6,  10,  30, -77,  13;
/M: SY='S';  M= -58, -73,  16,  22,   2, -70, -63,   1,  11,   5, -51, -15, -70, -54,  11,  47,  12,  -6, -79, -62;
/I:         I=-11; MD=-28;
/M: SY='D';  M= -33,   1,  63, -52, -61, -73, -57, -66, -28, -36,  -9, -32, -74,  28,  20, -39,  31, -11, -72,  59; D=-11;
/I:         I=-11; MD=-28;
/M: SY='Y';  M=  16, -75, -69, -24, -22, -72, -62, -25,  19, -16,  -7, -16,  -9,  -6, -62,   0, -18,  28,  14,  64; D=-11;
/I:         I=-11; MD=-28;
/M: SY='F';  M= -30, -78, -72, -53,  39, -77,  28,  27,  25,  -1,  22, -18, -24, -12,  -1,   1, -62, -28, -65,  38; D=-11;
/I:         I=-11; MD=-28;
/M: SY='V';  M=   6, -77,  -1,   1, -68, -35,   2,  14,  -5, -60,   3, -34, -18,  35,  11, -60,  -1,  36,  18, -17; D=-11;
/I:         I=-11; MD=-28;
/M: SY='W';  M= -72, -80, -87, -81,  45, -84, -75,   0, -36,  42,   4, -81, -85, -75, -77,  -7, -17, -28,  98,  21; D=-11;
/I:         I=-11; MD=-28;
/M: SY='P';  M= -32, -98,   4,  38, -96, -88,  26, -33, -34, -89, -82, -19,  42,  11, -23, -74, -28, -37,-101, -85; D=-11;
/I:         I=-11; MD=-28;
/M: SY='P';  M= -21,-100, -88, -81, -20,  -5,  24, -86,  -7, -30, -81, -83,  41, -15,  12, -81, -84, -22, -98, -83; D=-11;
/I:         I=-11; MI=0; MD=-28; IM=0; DM=-28;
/M: SY='K';  M= -16, -88,  -6, -34, -78, -82,  -2,  -7,  32, -47, -72,   2, -84, -13,   0,   6, -69,  -1, -88,  13; D=-11;
/I:         I=-11; DM=-28;
/M: SY='V';  M= -30, -78,   3, -64, -13, -23,  36, -14,   2, -16, -11,   3,  17,  -4,   3, -64, -11,  42, -82, -14; D=-11;
/I:         I=-11; DM=-28;
/M: SY='D';  M=  -9,  31,  40, -62,  22, -72, -64, -13,  -3,  -6,  25,  35, -77, -65, -67, -19, -13,  21, -77,   7; D=-11;
/I:         I=-11; DM=-28;
/M: SY='R';  M= -18, -79, -65,   1, -67, -10, -29, -23,  36,  15, -57, -61, -20,  25,  51, -21, -19, -36, -75,   2; D=-11;
/I:         I=-11; DM=-28;
/M: SY='E';  M= -10, -78,  37,  55,  23, -26, -59, -69, -55, -41, -12,  18, -69,  45, -61, -17, -39, -11, -77, -18; D=-11;
/I:         I=-11; DM=-28;
/M: SY='G';  M= -63, -78,  16,   8,  45,  50, -64, -18, -26,  -7, -62,  19, -75, -65, -70, -24, -64, -24, -68,  18; D=-11;
/I:         I=-11; DM=-28;
/M: SY='K';  M=   2, -76,  -7,   3, -75,  -5, -15, -28,  37, -69,   5, -15,  32, -57,   3, -19,  30,  10, -83, -70; D=-11;
/I:         I=-11; DM=-28;
/M: SY='N';  M= -64, -78,  36,  43,  20,  11, -59, -74,   8, -37, -70,  56,  10, -54, -61,  -9, -54, -35, -81, -66; D=-11;
/I:         I=-11; DM=-28;
/M: SY='S';  M= -59, -73, -64, -61, -65, -31,  26, -62, -27,  23,  10,  -2, -72,  32,  21,  45,  36, -62, -79,  -4; D=-11;
/I:         I=-11; DM=-28;
/M: SY='E';  M=-112,-131,  81,  99,-135,-121,-103,-135, -95,-129,-126, -97,-109, -89,-105,-106,-109,-128,-137,-122;
/M: SY='I';  M=  11,  23, -82, -77, -51, -81, -76,  53, -76,  50, -40, -76, -79, -73, -77, -67,   2,  21, -76, -10;
/M: SY='C';  M=  13,  67, -73, -71, -65, -41, -77, -15, -69, -54,  -6, -65, -74, -71, -74,   2,  52,  62, -88, -68;
/M: SY='L';  M= -64,  -5, -82, -76,  14, -85, -74,  38, -73,  49,  24, -76, -80, -13, -26, -70,   5,  40, -75, -55;
/M: SY='W';  M= -67, -78, -85, -80,  17, -84, -68,  36, -75,  14,  31, -81, -82, -73, -75, -74, -64,  39,  94,  68;
/M: SY='K';  M= -63,  -3,  19,   5, -18, -70,  -7, -68,  43,  -8, -62,  30, -70,  20,  31, -10,  27, -27, -81, -64;
/M: SY='L';  M=   0,  36,  13, -68,   2, -76,  43, -45, -71,  52, -45, -27, -79, -68, -72, -14, -16,  26, -80, -57;
/M: SY='P';  M=   5, -79,  41, -53, -81,  -9,  40, -55,  12, -78, -70,  -7,  76, -58, -63,  19, -17, -35, -86, -71;
/M: SY='R';  M= -26,  26, -22, -56, -75, -31,  -6, -74,  11, -34, -27,   5, -11,  13,  63,  38,  24, -70, -82, -67;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='N';  M= -64, -74, -66, -71, -59,   8, -64,  16, -68,  38,  49,  59,  37, -66, -72, -63, -59,   4, -81, -65;
/M: SY='P';  M= -65,  38, -16,  60, -15, -72, -64, -76, -24, -42, -70,  11,  88, -55, -65, -61, -10, -75, -82, -74;
/M: SY='K';  M=  -6, -39,  26, -52, -73,   0,  -2, -68,  54,   4,  23, -39,   8,  23,   6,  -9, -26, -68, -79, -66;
/M: SY='F';  M= -18, -75, -79, -74,  86, -15,  -6,  -1, -25,   7, -52, -73,  43, -76, -73, -24, -64, -10, -59, -40;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='R';  M= -33,  -7, -25, -56, -71, -75, -62, -18,  29, -40, -64, -60,  11,  -8,  83, -22, -27, -30,  68, -62;
/M: SY='D';  M= -66, -80,  99, -13, -86, -64, -55, -85,  27, -84, -79,  35, -68,  -5, -56,  -4, -57, -82, -96, -71;
/M: SY='I';  M= -14, -76, -75, -77, -11, -80,   0,  70, -73,  33, -42,  28, -79, -69, -74, -68, -61, -31, -66,  47;
/M: SY='R';  M= -63, -74, -68, -13,  44, -78, -64, -19,  11, -34,   4, -62, -74, -58,  56, -18,  39,  26, -71,  -7;
/M: SY='K';  M= -15,  44,  30,  -3, -23,   7, -61, -76,  54, -25, -68,  24, -17, -22, -13,  15, -57, -72, -81, -69;
/M: SY='H';  M= -70,  12, -69, -28,  53, -77,  83, -22,  13, -16,  25, -16, -77, -12, -24, -67, -67, -64,  56,  55;
/M: SY='F';  M= -72, -75,  33, -72,  93, -81, -66,  28, -74, -11, -52, -21, -82, -78, -75, -71, -35, -16, -54,  26;
/M: SY='P';  M=  13,   7, -71, -65, -67, -70,  -5,  11, -65,   4,  -2, -66,  63, -17, -19,  24,   4,  20, -82, -67;
/M: SY='E';  M= -30, -77,  47,  59, -27, -70, -59, -72,  38, -46, -69,  12, -12, -48, -29, -14,  13, -14, -84, -69;
/M: SY='K';  M=  -6, -77,  45,  27, -79, -67, -58, -77,  56, -77, -70,  14, -67,   6,  20,  -1,   9, -46, -82, -34;
/M: SY='E';  M=  14, -76,  34,  45, -22,  -8, -64,  23,   1, -23, -63, -42,  -9, -54, -21,  21, -28, -59, -80, -67;
/M: SY='D';  M= -52, -22,  63,  36, -19,  -9, -59, -67, -57,   9, -55, -11, -20,  15, -16,  -1,   0, -33, -81, -11;
/I:         I=-17; MD=-44;
/M: SY='P';  M= -64, -81,  38,   3, -72,  11, -10,  -2, -29, -34,  25, -62,  42,   5, -30, -63,  -4,  25,  31, -68; D=-17;
/I:         I=-17; MD=-44;
/M: SY='Y';  M= -16,   1,   5,   9, -17,  -3, -64, -75,   9, -13, -68,   0,  -9,   2,  -4,   0,  -2, -74, -76,  33; D=-17;
/I:         I=-17; MD=-44;
/M: SY='P';  M= -39, -86, -20, -69, -23, -19, -72,  -2,  13,   3, -66,  40,  48, -68,   3, -69, -25, -33, -88, -75; D=-17;
/I:         I=-17; MD=-44;
/M: SY='A';  M=  30, -89, -87, -84,  14, -82, -84, -78, -38,  -2, -75, -14,   5, -82, -86,   8, -27, -76, -88,  -8; D=-17;
/I:         I=-17; MI=0; MD=-44; IM=0; DM=-44;
/M: SY='T';  M=   2, -90,   3, -38, -89, -12,   7, -77, -19, -22, -78, -17, -89, -20, -82, -13,   7,   4,-103, -85; D=-17;
/I:         I=-17; DM=-44;
/M: SY='C';  M= -56,  67, -84, -84,  50, -16, -27, -60, -34,  -9,  53, -11, -87, -81, -80, -72,  14,   0, -80, -59; D=-17;
/I:         I=-17; DM=-44;
/M: SY='P';  M= -61,  19, -18, -24, -80, -11, -66, -71,  11, -77, -71,  32,  40, -59,  16,  39,  10,   5, -88, -75; D=-17;
/I:         I=-17; DM=-44;
/M: SY='A';  M=  31,   2,   8,  30, -70,   2, -67, -59, -61,  15, -59, -12, -72,  11, -24, -24,   5,   8, -83, -70; D=-17;
/I:         I=-17; DM=-44;
/M: SY='A';  M=  62,   3,  19,   4, -72, -62,   6,  -2,  -8, -40, -61, -59, -69, -14, -64,   7, -18,  -5,  23, -67;
/M: SY='T';  M= -48,   5, -75, -71,  24,   5, -71, -14, -65,  22,  27, -67,  11, -68,  16, -31,  38,  30, -76, -58;
/M: SY='Y';  M= -17,   5, -75, -75,   8, -13, -65, -41, -72,  47, -44,  19, -82, -70, -73, -43, -60,  42, -66,  51;
/M: SY='M';  M=   6,  23, -69, -14, -22, -57,  -4,  11, -63, -54,  41, -62, -17, -63,   0,  27,  35,  40, -83, -63;
/M: SY='C';  M= -61,  44,   7, -28,  14,   8, -65,  -1,   8,  -3,   2,  28, -74,  -8, -64,  -2,  13,  -6,  35, -12;
/M: SY='K';  M= -64, -78,  27, -52, -72,  -3,  35,  -2,  45, -40,   8,  41,  -4,  21,  18, -27, -20, -68, -80,  -6;
/M: SY='M';  M=   0, -72, -36, -68,   5, -70,   3, -12, -64, -23,  55,   5,  -7, -63, -26,  17,  34,  10,  33,  45;
/M: SY='N';  M= -61, -76,  53,  35, -82, -30, -55, -80, -17, -56, -74,  68,  40, -51, -61,  34, -53, -78, -90, -74;
/I:         I=-14; MD=-34;
/M: SY='Q';  M= -15, -78, -20, -26, -81,  -1, -66, -69,  22, -75, -68,  21,   8,  35,  10, -11,  34,   8, -87, -74; D=-14;
/I:         I=-14; MD=-34;
/M: SY='F';  M= -43, -93,   1, -87,  48, -13, -87, -73, -86, -44,  20, -83, -16, -89, -27, -34,  -4,  -5,  12, -66; D=-14;
/I:         I=-14; MI=0; MD=-34; IM=0; DM=-34;
/M: SY='T';  M= -41, -94, -22, -36,   9, -35, -84, -78, -87,  -5,  -9, -83,  -1, -86, -91, -34,  34, -79, -87,  27; D=-14;
/I:         I=-14; DM=-34;
/M: SY='N';  M=  -7, -94,  14, -73, -92,  -6, -78, -91, -39, -27, -84,  45,  -3,  20, -81, -26, -76, -91,  40, -85; D=-14;
/I:         I=-14; DM=-34;
/M: SY='M';  M= -37, -89, -80, -24, -10, -20,  26, -32, -76, -48,  52, -28, -85,  29, -78, -18,  26, -35,  45, -69; D=-14;
/I:         I=-14; DM=-34;
/M: SY='Y';  M= -81, -88, -91, -85,  30, -94,  21,  -2, -20,  34,  24, -86, -45, -80, -80, -84, -46, -35,  24,  46; D=-14;
/I:         I=-14; DM=-34;
/M: SY='I';  M= -18, -84, -16, -35, -61, -83, -67,  49, -63, -57,  36,   0, -81,  12,  32, -69, -24,  -9, -75,  42; D=-14;
/I:         I=-14; DM=-34;
/M: SY='P';  M=  20,   8, -66,   4, -19, -70, -72, -23,  -6, -39, -68, -41,  73, -64, -69,  13,  31, -66, -83, -74; D=-14;
/I:         I=-14; DM=-34;
/M: SY='V';  M= -38,  -3, -67,  29,  -8, -80, -72,  24, -27, -53,  12, -18, -74, -34, -33, -11,  11,  56, -80,  -2; D=-14;
/I:         I=-14; DM=-34;
/M: SY='W';  M=   0, -80,  32, -60, -66,  28,   7, -26,  -2,  -5,  41, -59, -74,  25,   9, -24, -65, -67,  42,  18; D=-14;
/I:         I=-14; DM=-34;
/M: SY='P';  M=   3,   1,  10, -17,  19, -38, -65,  -9,  21, -37, -64, -64,  37, -15,  10, -16, -18, -66, -70,  36; D=-14;
/I:         I=-14; DM=-34;
/M: SY='V';  M= -39,  -5, -30,   7, -62, -33, -73, -45, -70,  26, -53, -27, -29, -10, -74,   0,  16,  50, -84,  -8; D=-14;
/I:         I=-14; DM=-34;
/M: SY='W';  M= -83, -32,   3, -80, -88,   4, -90,   0,   8, -26, -78, -82,  21, -19, -29, -83, -82,  -3,  23, -86; D=-14;
/I:         I=-14; MI=0; MD=-34; IM=0; DM=-34;
/M: SY='E';  M= -10, -78,  42,  60, -83,   2, -57, -81,  14, -78, -71,  13, -64,  44, -25, -27,  14, -75, -84, -71;
/M: SY='K';  M=  25,  -8, -71, -62,  25, -72, -70,  -6,  49, -16, -55, -64, -10, -60,   6, -21, -23,  38, -74, -59;
/M: SY='I';  M=   1, -73, -73, -69, -58, -78,  33,  38, -41,  18, -47, -18, -76, -63,  36, -62,  18,  37, -79, -14;
/M: SY='T';  M= -59,   3,  21,  16, -72, -71,  33,   8,  -3, -51, -61, -30,  -7,  29, -60,   2,  67, -18, -87, -65;
/M: SY='Y';  M=  -7, -80, -66,  22, -44, -32,  28,  12, -12,   4, -18, -68, -76, -57,  10, -65, -65, -32,  32,  87;
/M: SY='D';  M= -23, -77,  32, -21,  15,  27,  -3, -69,  20, -72, -67,   6,  24,  14,  -5,   2, -17,  -2, -77, -29;
/M: SY='F';  M= -13,   5,  12,   6,  46,  16,  28, -63, -62,  -5,  -1,  25, -17,  33, -65, -59, -25, -22, -72, -11;
/M: SY='Y';  M= -12,  19,  15,   5, -17,  -9, -64,   3,  31,   0, -58, -61,  23, -59, -60,  -1,  -8, -12, -71,  34;
/M: SY='N';  M= -27, -72, -19,  -9, -60,  -1, -66,  29, -25,  14, -52,  41, -74, -63, -52,  15, -22,  35, -80,  -4;
/I:         I=-22; MD=-55;
/M: SY='N';  M= -39,  28,  20, -79, -20, -89, -15, -76, -25, -47, -82,  39, -10, -83, -86, -78, -24,  15,-108, -85; D=-22;
/I:         I=-22; MD=-55;
/M: SY='M';  M= -83,   7,  -6, -92, -93, -24, -96, -22, -91, -81,  30, -86, -99, -91, -31,  -9,  14,  15,-113, -92; D=-22;
/I:         I=-22; MI=0; MD=-55; IM=0; DM=-55;
/M: SY='N';  M= -30,  -7,   6,  20, -20,  17, -61, -61, -60,  23,   7,  38, -23, -21, -15,  15,  -3, -33, -78, -10;
/M: SY='S';  M= -29, -74,  28,  29, -30,  36, -62, -78,  19, -45, -71,  -5, -17, -53, -59,  48,   8, -73, -81, -70;
/M: SY='G';  M= -33, -78,  -1,  19, -25,  85, -68, -83, -22, -82, -74,  -6, -69, -62, -71, -37, -66, -34, -77, -74;
/M: SY='T';  M= -10,   3,   5,   3, -70, -69, -63,  -2,   9,  -5, -58,  24, -70,  16,   9,   9,  44,  -2, -84, -67;
/M: SY='Y';  M= -67,   6, -64,   0, -43, -36,  10, -66, -27, -37, -58, -42,  39,  30, -20, -60,  22, -67, -51,  98;
/M: SY='T';  M= -59, -72, -65,  -3,  11, -75, -65,   4, -55, -27,  31, -59, -17,  29,  30,   0,  64,   9, -78, -60;
/M: SY='N';  M=   7, -74,   9, -56, -19, -64,  58, -25, -15, -42,  -4,  63, -11,  25,  10,  -5,   8, -32, -85, -61;
/M: SY='R';  M= -65, -81, -19,  37, -72,  -9,  35,  17,  23, -31,  -2, -58, -20,  -8,  63, -62, -30, -33, -80, -64;
/M: SY='M';  M= -15,  39,  -6, -67, -23, -75, -67,  45, -67,   7,  48, -11, -74,  19, -70,  -3,  33,  -7, -78,  -6;
/I:         I=-36; MD=-90;
/M: SY='P';  M= -78,  38, -38, -84, -94,  11, -88, -87, -82, -94, -87, -81,  56, -84, -16,   7, -28, -12,-100, -25; D=-36;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='I';  M= -69, -79, -84, -78,  -6, -87, -71,  72, -73,  38,  19, -78, -80,  -5, -24, -75, -64, -36,  56,  37;
/M: SY='M';  M=  -6, -75, -16,  28, -67, -69,  35, -12, -12, -60,  58, -57, -69,  25,  12,  29,   9,  -8,  25, -10;
/M: SY='Y';  M= -35, -82, -74, -75,  26, -75, -47, -61, -68, -57, -55, -72, -82, -64, -66,  10, -65, -65,  77, 118;
/M: SY='N';  M=  -6, -77,  22,   9, -77, -29,  47, -77,  14, -77, -68,  59, -11,  -7,  40, -40,   2, -38,  22, -65;
/M: SY='Y';  M=  37,   3, -73, -71,  51,  -8,  16, -56, -65, -32,  21, -21, -77, -66,   1, -59, -19,   6, -59,  60;
/M: SY='P';  M= -20, -10, -56,  33, -82, -33,   7, -72,  26, -78, -68,  25,  83,  15, -58, -30, -59, -13, -82, -74;
/M: SY='T';  M=  15,  10,   5, -61, -73,  -6, -67, -67, -60, -70, -66, -12, -65, -61, -68,  32,  88, -59, -88, -70;
/M: SY='R';  M= -63,  35, -62,  16, -70, -76, -61,  -1,  44, -37,   5, -59, -72,  27,  59,  -7, -26,  -1, -77, -14;
/M: SY='N';  M=  38, -72, -13, -57, -77, -22, -62, -70,  24, -40, -11,  47,  41, -56,  -2,  -2,  30, -66, -83, -71;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='G';  M= -55, -78, -11,  13, -79,  84,  29, -85, -64, -83, -73,  25, -70, -61, -71, -28, -65, -39, -79, -20;
/M: SY='D';  M= -68, -82,  82, -44, -15, -70,   2, -71, -56, -40,  47, -14, -72,  59, -22, -60, -63, -74,  62,  25;
/M: SY='C';  M=-111, 158,-130,-131,-121,-126,-130,-128,-126,-118,-119,-117,-141,-134,-133,-113,-111,-115,-151,-132;
/M: SY='G';  M= -51, -78, -66, -78, -84, 100, -73, -92, -71, -87, -77, -52, -70, -69, -79, -51, -28, -85, -76, -79;
/M: SY='G';  M=  31, -71, -66, -67, -75,  58, -66, -72, -63, -38,  40, -55, -69, -60, -11,  54, -20, -66, -79, -70;
/M: SY='L';  M=  31,  10, -81, -74, -56, -76, -77,  35, -74,  41,  -4, -77,  19, -72, -77, -65, -59,  40, -79, -63;
/M: SY='L';  M= -22,  31, -85, -79, -49, -85, -75,  44, -78,  54,  20, -80, -82, -74, -78, -72, -60,  42, -76,  -6;
/M: SY='M';  M= -62,  27, -80, -77, -10, -21, -72,  38, -74,  27,  46, -72, -78, -72, -76, -66,  26,  41, -73,  23;
/M: SY='C';  M=  53,  61, -68, -64, -70, -61, -69,  -8, -16, -11,  -1, -59, -71, -61, -18,  44,  23, -55, -82, -69;
/M: SY='T';  M= -27,   6,  -8,  -5, -69, -68,  19,   6,  21, -66, -25,  38, -17,  37, -56,   1,  40,  -8, -80,   7;
/M: SY='N';  M= -60, -74,   8,   6, -19,  34, -67,  34, -66,   5, -54,  47, -74, -64, -72, -21, -58,  28, -81, -65;
/M: SY='K';  M= -10, -78,   3,  22, -80,  37, -60, -77,  46, -43, -67,  11, -68,  38,  14, -20, -26, -35, -79, -70;
/I:         I=-31; MD=-79;
/M: SY='G';  M= -28, -88, -74, -75, -90,  68, -76, -95,  10, -92, -82, -25, -80,   6, -10, -19, -22, -89, -85, -22; D=-31;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='K';  M= -75, -91,   7,  -9, -42, -38,  38, -20,  45, -83, -75,  -8, -80,  41,  10, -31, -34, -82, -89, -27; D=-31;
/I:         I=-31; DM=-79;
/M: SY='R';  M= -76,  23, -73, -70, -14, -32,  20, -83,  26, -80,  23,  25,  28, -66,  30, -70,  -5, -82,  23, -13; D=-31;
/I:         I=-31; DM=-79;
/M: SY='K';  M=   2,   0, -73, -61, -18, -82, -73, -37,  75, -82, -75, -66, -80, -20,  20, -69, -71, -36, -85, -75; D=-31;
/I:         I=-31; DM=-79;
/M: SY='I';  M= -29, -75, -86, -82, -52, -88, -86,  84, -79,  -1, -39, -79, -78, -77, -81, -72, -58,  57, -80, -60;
/M: SY='V';  M= -35,   2, -85, -80,   8, -86, -78,  51, -78,  35,   8, -80, -81, -76, -78, -72, -59,  59, -74,  -4;
/M: SY='G';  M= -16,   9, -65, -75, -82, 100, -71, -89, -70, -85, -74, -51, -69, -67, -77, -49, -67, -82, -74, -78;
/M: SY='M';  M= -62, -72, -82, -77,   9, -81, -67,  65, -72,  17, 105, -72, -73, -66, -72, -24, -15, -11, -72, -51;
/M: SY='H';  M= -68,   2, -59, -58, -61, -74, 137, -67, -62,  22, -48, -49, -73, -52, -57, -62, -66, -32, -95, -41;
/M: SY='V';  M= -27,   3, -79, -75, -13, -78, -81,  35, -73, -42, -45, -72, -76, -73, -75,  14, -22,  86, -83, -60;
/M: SY='A';  M=  79, -65, -66, -63, -77,  45, -69, -69, -64, -71, -65, -58, -19, -60, -69,  18, -53, -30, -76, -72;
/M: SY='G';  M= -49, -75, -62, -28, -81,  95, -68, -86, -66, -83, -73, -50, -67, -13, -73,   8,   1, -79, -75, -75;
/M: SY='N';  M= -58, -72,  25, -58, -70,  41, -55, -20,  -3, -18, -64,  79, -71, -55,  -9,  10, -14, -32, -81, -12;
/M: SY='G';  M=  -3, -75,  39, -55, -73,  56, -59, -74,  17, -42,  10,  29, -69, -19,  29, -23, -59, -37, -77,  -5;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='G';  M= -21,  30, -57,  10, -74,  52,  46, -81,  23, -76, -67, -19, -68,  -8,  39,  14, -19, -75, -77, -10;
/M: SY='M';  M= -31, -74,   8, -24, -65, -72,  40,  20,  25, -17,  55, -12, -69,  47,   2, -29,  15,  15, -80, -59;
/M: SY='G';  M=  12, -71, -64, -68, -72,  79, -67, -72, -65, -34, -66, -52, -67, -13, -71,  11,  33, -31, -74,  -6;
/M: SY='Y';  M=   2, -10, -78, -75,  63, -33, -58, -19, -70, -48,  38, -73, -79, -69, -70, -65, -23,  20,  72,  85;
/M: SY='A';  M=  76,  43, -66, -61, -73, -54, -69, -61, -63, -66, -61, -59, -17, -60, -68,  42,   3,   6, -80, -70;
/M: SY='C';  M=  40,  76,   6,  -3, -74, -27, -65, -22,  12, -69, -65, -54, -68, -13, -21,  45,   6, -30, -82, -70;
/M: SY='P';  M=   6,  10, -69, -25, -54, -28, -64,  30, -24,  30,  24, -17,  32, -14, -67,  10, -15, -13, -70,  28;
/M: SY='M';  M= -63, -70, -82, -77,  14, -84, -71,  46, -75,  58,  60, -21, -79, -71, -75, -72, -59,  33, -72, -52;
/M: SY='P';  M= -31,   1, -63, -58, -66, -67, -64, -26,  14,  -2, -60,  -7,  86, -60, -63,  22,  40, -62, -75,  14;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='Q';  M= -62,   9, -21, -17, -75, -69,  43, -71,  34, -13, -60,   4,  40,  64,  45, -13, -22, -41, -79, -63;
/M: SY='E';  M= -13, -75,   7,  64, -74, -54,  47, -27, -24, -15, -63,  22,  18,  -9, -37,  37, -54, -37, -83, -65;
/M: SY='M';  M= -34,  25,  42,   9, -52, -71,  27, -25, -58, -17,  80, -57,  -6, -55,  -6,   8, -30, -59, -66,  64;
/M: SY='F';  M= -68, -72, -84, -78,  82, -83, -70,  35, -76,  40,  32, -77,  13, -76, -75, -72, -21,  -6, -58, -38;
/I:         E1=0; IE=-380; DE=-380;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2021_03 which contains 565'254 sequence entries.


Total number of hits 112 in 112 different sequences
Number of true positive hits 112 in 112 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.12 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotic viruses
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] Peptidase C3
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
112 sequences

POL1_APMV   (Q02941    ), POL1_ARMVN  (Q6W8W5    ), POL1_BBWV2  (Q9WNW0    ), 
POL1_BBWVS  (Q76L40    ), POL1_BPMV   (Q9YJU5    ), POL1_BRAV   (Q8V5E0    ), 
POL1_BRSV   (P18522    ), POL1_CNSV   (Q8QVV0    ), POL1_CPMVS  (P03600    ), 
POL1_CPSMV  (P36312    ), POL1_CRLVP  (Q6EWG9    ), POL1_GCMV   (P13025    ), 
POL1_GFLV   (P29149    ), POL1_RCMV   (P35930    ), POL1_RRVC   (Q6W8W4    ), 
POL1_SDVS5  (Q9WAL8    ), POL1_TBRVM  (Q8B8X3    ), POL1_TORVR  (P29150    ), 
POL1_TOTV   (A1XIP9    ), POL1_TRSVB  (Q88893    ), POLFS_SINV3 (C1JCT2    ), 
POLG_AEVCA  (Q9YLS4    ), POLG_AEVL2  (Q6WQ42    ), POLG_AEVVR  (Q6R325    ), 
POLG_BOVEV  (P12915    ), POLG_COSAA  (B8XTP8    ), POLG_CX16G  (Q65900    ), 
POLG_CX16T  (Q9QF31    ), POLG_CXA21  (P22055    ), POLG_CXA24  (P36290    ), 
POLG_CXA9   (P21404    ), POLG_CXB1J  (P08291    ), POLG_CXB2O  (Q9YLG5    ), 
POLG_CXB3N  (P03313    ), POLG_CXB3W  (Q66282    ), POLG_CXB4E  (Q86887    ), 
POLG_CXB4J  (P08292    ), POLG_CXB5P  (Q03053    ), POLG_CXB6S  (Q9QL88    ), 
POLG_EC01F  (O91734    ), POLG_EC05N  (Q9YLJ1    ), POLG_EC06C  (Q66474    ), 
POLG_EC09B  (Q66577    ), POLG_EC09H  (Q66849    ), POLG_EC11G  (P29813    ), 
POLG_EC12T  (Q66575    ), POLG_EC30B  (Q9WN78    ), POLG_ECHO9  (P08490    ), 
POLG_EMCV   (P03304    ), POLG_EMCVB  (P17593    ), POLG_EMCVD  (P17594    ), 
POLG_EMCVR  (Q66765    ), POLG_ENMGO  (P12296    ), POLG_FMDV1  (P03306    ), 
POLG_FMDV5  (P03307    ), POLG_FMDVA  (P03308    ), POLG_FMDVC  (P03309    ), 
POLG_FMDVI  (P03310    ), POLG_FMDVO  (P03305    ), POLG_FMDVS  (P03311    ), 
POLG_FMDVT  (P15072    ), POLG_FMDVZ  (P49303    ), POLG_HAV88  (Q8V0N6    ), 
POLG_HAVCF  (Q5Y944    ), POLG_HAVGB  (Q67825    ), POLG_HAVH2  (A3FMB2    ), 
POLG_HAVHA  (Q05794    ), POLG_HAVHM  (P08617    ), POLG_HAVJ8  (A5LGW7    ), 
POLG_HAVLA  (P06441    ), POLG_HAVMB  (P13901    ), POLG_HAVNO  (Q9DWR1    ), 
POLG_HAVS2  (P14553    ), POLG_HE701  (P32537    ), POLG_HE71   (B9VUU3    ), 
POLG_HE71B  (Q66478    ), POLG_HE71M  (Q66479    ), POLG_HED68  (Q68T42    ), 
POLG_HKV1   (C6KEF6    ), POLG_HPE1H  (Q66578    ), POLG_HPE2W  (O73556    ), 
POLG_HPEV5  (Q9YID8    ), POLG_HRV14  (P03303    ), POLG_HRV16  (Q82122    ), 
POLG_HRV1A  (P23008    ), POLG_HRV1B  (P12916    ), POLG_HRV2   (P04936    ), 
POLG_HRV3   (Q82081    ), POLG_HRV8A  (P07210    ), POLG_PEV9U  (O41174    ), 
POLG_POL1M  (P03300    ), POLG_POL1S  (P03301    ), POLG_POL2L  (P06210    ), 
POLG_POL2W  (P23069    ), POLG_POL32  (P06209    ), POLG_POL3L  (P03302    ), 
POLG_PYFV1  (Q05057    ), POLG_RTSVA  (Q83034    ), POLG_RTSVT  (Q91PP5    ), 
POLG_SAFV   (C0MHL9    ), POLG_SALVA  (C5MSH2    ), POLG_SVDVH  (P16604    ), 
POLG_SVDVU  (P13900    ), POLG_SVV1   (Q155Z9    ), POLG_TMEVB  (P08544    ), 
POLG_TMEVD  (P13899    ), POLG_TMEVG  (P08545    ), POLN_ABPVR  (Q9DSN9    ), 
POLN_CRPVC  (Q9IJX4    ), POLN_DCVEB  (O36966    ), POLN_EOPV   (Q6UP17    ), 
POL_SINV3   (C1JCT1    )
» more

UniProtKB/Swiss-Prot
False negative sequences
1 sequence

POLG_AIVA8  (O91464    )

		
PDB
[Detailed view]
32 PDB

1CQQ; 1HAV; 1L1N; 1QA7; 2A4O; 2B0F; 2BHG; 2CXV; 2H6M; 2H9H; 2HAL; 2IJD; 2IN2; 2J92; 2VB0; 2WV4; 2WV5; 2XYA; 2ZTX; 2ZTY; 2ZTZ; 2ZU1; 2ZU3; 4DCD; 5FX5; 5FX6; 5IYT; 6FFN; 6FFS; 6KYZ; 6KZ0; 6L0T
» more

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View entry in raw text format (no links)
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