PROSITE entry PS51874
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General information about the entry
| Entry name [info] | PCV_3C_PRO |
| Accession [info] | PS51874 |
| Entry type [info] | MATRIX |
| Date [info] |
10-APR-2019 CREATED;
07-APR-2021 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51874 |
| Associated ProRule [info] | PRU01222 |
Name and characterization of the entry
| Description [info] | Picornavirales 3C/3C-like protease domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=200; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=195; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.8413713; R2=0.0100723; TEXT='-LogE'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=20654.7421875; R2=11.8387909; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=1059; H_SCORE=33192; N_SCORE=12.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=463; H_SCORE=26136; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-28; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='G'; M= 28, -76, 33, -31, -78, 64, -63, -79, -23, -44, -70, 16, -13, 17, -67, -26, -61, -74, -78, -12; /M: SY='P'; M= 37, -79, -70, -62, -72, -13, -69, -64, -66, -40, 13, -70, 97, -66, -74, -25, -59, -12, -75, 13; /M: SY='A'; M= 28, -2, 5, 23, -69, -28, -61, -62, -24, -40, -63, 5, -10, 20, 3, 25, -35, 16, -77, 20; /M: SY='M'; M= -2, -75, 9, 14, 36, -13, -6, -26, -14, -5, 55, -60, -71, 4, 8, 10, 1, -60, 30, -54; /M: SY='D'; M= -59, -78, 67, 40, -83, 18, 28, -80, -26, -80, -74, 6, -16, 14, -60, 32, -57, -35, -89, -70; /M: SY='F'; M= -37, -77, -1, 10, 70, -78, -62, -20, -63, 23, 8, -67, -22, 63, -64, -66, -65, -26, -62, 0; /M: SY='A'; M= 44, -72, 33, 33, -75, 12, -63, -12, -59, -19, -8, -14, -68, -4, -65, 32, -55, -62, -82, -70; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='E'; M= -25, -73, -5, 38, -62, -74, 16, -27, 4, 25, 12, 2, -70, -28, -25, 0, 15, 14, -80, -8; /M: SY='S'; M= 25, -72, -2, 25, -6, 15, 11, -70, -25, -28, 2, 32, -69, -55, -63, 40, -55, -39, 19, -12; /M: SY='M'; M= -64, 7, -77, -16, -52, -38, 27, 34, -26, 38, 40, -73, -31, -67, -29, -70, -61, 39, -75, 15; /M: SY='M'; M= 37, -71, -21, -26, -21, -74, -70, 20, -69, 44, 55, -73, -18, -66, -26, -64, -60, 9, -76, -60; /M: SY='K'; M= -16, -78, -14, 20, -73, -28, 26, -19, 55, -10, -60, -22, -5, 8, 33, -18, -60, -5, -80, -65; /M: SY='K'; M= -24, -75, -18, -54, -23, -11, 27, -73, 54, -71, 31, 47, -70, 0, 37, -23, 19, -71, -80, -63; /M: SY='N'; M= -40, 37, -53, -12, -31, -29, 8, -46, -57, -37, 51, 83, -73, 28, -62, 10, -14, -23, 28, -64; /M: SY='L'; M= -15, -31, -73, -66, -59, -30, -10, 19, 11, 36, 27, -66, -74, 13, -12, -24, 26, 21, -79, -61; /M: SY='C'; M= 22, 71, -76, -71, -54, -74, -67, -46, -67, 9, -21, -71, -12, -8, -13, -12, -58, 46, -71, 52; /M: SY='C'; M= -31, 58, -69, -62, -64, -30, -67, 7, 0, -7, -56, -23, 15, 41, 19, -58, 32, 10, 24, 4; /M: SY='I'; M= 1, -73, -78, -24, 18, -33, -70, 46, -72, 12, 41, -73, -76, -70, -74, -65, 6, 36, -68, 33; /I: I=-31; MD=-79; /M: SY='T'; M= 3, 21, -10, -64, -27, 24, -65, -34, -10, -8, -61, 5, -73, 12, -3, 5, 28, -1, -77, 13; D=-31; /I: I=-31; MD=-79; /M: SY='T'; M= -63, 9, 9, -30, 23, -78, -68, 20, -69, 16, 40, -46, -75, -68, -73, -7, 51, 8, -75, 9; D=-31; /I: I=-31; MI=0; MD=-79; IM=0; DM=-79; /M: SY='P'; M= 0, -76, 14, 31, -9, 9, -63, -58, -16, -36, -6, -13, 47, -55, 9, 21, 6, -35, -80, -68; /M: SY='T'; M= -32, -74, 6, -2, -72, 1, -59, -68, 43, -36, -12, 42, -68, 14, -5, -27, 44, -20, -79, -2; /M: SY='G'; M= -8, 7, -1, -68, -82, 86, -70, -41, -1, -81, -72, -10, -71, -21, -56, -52, -66, -34, -78, -76; /M: SY='E'; M= -29, 13, -2, 50, -75, -26, 43, -68, 15, -35, -64, 20, -69, -49, 31, 4, -29, 11, -85, -66; /I: I=-22; MD=-55; /M: SY='M'; M= -73, -84, -84, -82, 18, -87, 5, 12, -38, -19, 41, -1, 5, -78, -81, -2, -4, 23, -85, -11; D=-22; /I: I=-22; MI=0; MD=-55; IM=0; DM=-55; /M: SY='F'; M= -11, 58, -83, -78, 63, -43, -73, 28, -75, -6, 10, -40, -84, 18, -77, -69, -16, -2, -67, 6; D=-22; /I: I=-22; DM=-55; /M: SY='T'; M= -56, 11, -57, -58, -71, -64, 34, -67, -53, -70, -63, 40, -69, 36, 15, 48, 57, -8, -84, -7; /M: SY='C'; M= 41, 82, -75, -73, -68, 34, -74, 6, -71, -34, 50, -64, -75, -69, -75, -37, -1, 5, -82, -70; /M: SY='L'; M= -26, 50, -76, -75, -10, -79, -70, -2, -73, 59, 28, 7, -79, -71, -74, -65, 32, -3, -4, -58; /M: SY='G'; M= -14, -78, -17, -68, 25, 61, -66, -65, -64, 5, 40, -61, -18, 27, -3, -59, -67, -67, 42, -9; /M: SY='V'; M= -34, -72, -84, -79, 26, -85, -74, 32, -76, 14, -43, -79, -82, -76, -77, -70, -58, 72, -67, 44; /M: SY='R'; M= -67, 1, -65, -57, 9, -12, 39, -73, 45, -35, -62, -60, 41, -1, 52, -62, -24, -73, -66, 45; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='G'; M= -26, -77, 59, -57, -84, 69, 10, -86, -23, -85, -76, 17, -14, -60, -68, 16, -60, -81, -85, -74; /M: SY='R'; M= -65, -79, 11, -54, -76, 4, 37, -81, 30, -78, -68, 33, -72, -30, 72, -56, 21, -77, 45, -63; /M: SY='W'; M= -26, -6, -68, -18, 12, -70, -65, -2, -21, -16, -58, -19, -74, -17, 26, 45, -6, 10, 77, 19; /M: SY='F'; M= 8, 25, -83, -76, 56, -80, -72, 5, -75, 37, 9, -77, -82, -13, -75, -68, -61, 40, -67, 1; /M: SY='M'; M= 10, 10, -83, -76, -12, -81, -73, 35, -73, 49, 49, -77, -80, -71, -18, -69, -60, 33, -76, -58; /M: SY='M'; M= 12, 25, -81, -75, -13, -21, -71, 11, -73, 40, 73, -73, -78, -69, -74, -25, -22, 29, -77, -59; /M: SY='P'; M= -63, -11, -63, -61, -72, -70, 26, -64, -62, -72, -65, 27, 92, -65, -71, -54, 57, 0, -82, 3; /M: SY='R'; M= -11, -76, -62, -57, -68, 11, -49, -74, 35, -36, -64, -17, -71, -9, 64, 10, 31, -69, -73, 25; /M: SY='H'; M=-119,-130,-103,-103,-117,-120, 155,-136,-108,-118,-103, -92,-119, -97,-102,-108,-117,-135,-153, -86; /I: I=-20; MD=-51; /M: SY='Q'; M= -12, -85, -78, -27, 34, -36, -71, -24, -69, -7, 11, -73, -83, 68, -70, -21, -20, -1, -76, -4; D=-20; /I: I=-20; MD=-51; /M: SY='A'; M= 47, -80, -89, -83, 46, -79, -81, 19, -82, -17, 0, -83, -86, -81, -83, -69, -69, 1, 21, 0; D=-20; /I: I=-20; MD=-51; /M: SY='W'; M= -37,-101, -30, 8, -88, -47, -86, -84, 12, 14, -14, -86, -95, 20, -78, -36, -86, -86, 21, -86; D=-20; /I: I=-20; MI=0; MD=-51; IM=0; DM=-51; /M: SY='A'; M= 58, 26, -17, 1, 24, -31, -66, -28, -31, -12, 2, -62, -72, -2, 19, -6, -30, -58, -74, -61; /M: SY='E'; M= 13, -76, 22, 37, -18, -67, 7, 15, 7, -64, 27, 11, -17, 23, -25, 19, -56, -33, -80, -64; /M: SY='P'; M= -66, -84, 11, 20, -22, -35, -69, 3, 25, -8, -61, -66, 86, -60, -63, -65, -61, -6, 23, -69; /M: SY='G'; M= -9, -77, 43, 1, -73, 49, -64, -19, 0, -39, -69, 5, 1, -59, -65, -8, 11, -70, 38, -5; /M: SY='D'; M= -31, -1, 44, 22, -72, 8, -7, -75, 4, -35, -68, 7, 32, -18, -24, 10, 18, -72, -79, 20; /I: I=-38; MD=-97; /M: SY='N'; M= -31, -75, 13, 35, -24, -34, -60, -49, 15, -77, -70, 47, -2, 4, -19, 27, 35, -71, -85, -70; D=-38; /I: I=-38; MI=-97; MD=-97; IM=-97; DM=-97; /M: SY='I'; M= -63, -75, -76, -16, -55, -83, 5, 52, -70, 29, 28, -71, -77, -14, -25, -7, 10, 28, -79, -12; D=-38; /I: I=-38; DM=-97; /M: SY='M'; M= -64, -76, -71, -20, -56, -39, 31, 23, -63, -9, 53, 3, -76, -8, 6, -32, 18, 28, 27, 34; D=-38; /I: I=-38; DM=-97; /M: SY='V'; M= -29, 4, -77, -6, -15, -34, 4, 46, -72, 0, 37, -73, -77, -23, -73, -68, -59, 58, -75, 19; /M: SY='N'; M= -31, 2, 30, 27, 11, -31, 1, -3, -2, -34, -61, 30, -72, 2, 4, -9, -59, 5, -73, 29; /M: SY='G'; M= -15, 6, -8, -69, 30, 37, 28, 20, -62, -10, -57, 25, -76, -64, 17, -23, -63, -60, -68, 33; /M: SY='Y'; M= -7, -75, -3, -10, 25, -74, -25, -6, 21, -19, -55, -62, -73, 29, -15, -1, -2, 28, -67, 42; /M: SY='Q'; M= 23, 10, -9, 7, -26, -29, -8, -64, -18, -37, -13, -6, -37, 37, -61, 30, 36, -5, -79, -10; /M: SY='T'; M= -20, -73, 16, -63, 9, 1, 12, 13, -63, -49, -3, 23, 8, -19, -16, -30, 44, 28, -82, -61; /M: SY='N'; M= -9, -60, -25, 0, -77, 43, -61, -29, 8, -72, 16, 46, 3, -27, 20, -1, -6, -20, -82, -71; /M: SY='V'; M= -26, -1, 6, 10, -66, 14, -66, 6, 23, -47, -28, -58, -71, -58, 11, 6, 10, 30, -77, 13; /M: SY='S'; M= -58, -73, 16, 22, 2, -70, -63, 1, 11, 5, -51, -15, -70, -54, 11, 47, 12, -6, -79, -62; /I: I=-11; MD=-28; /M: SY='D'; M= -33, 1, 63, -52, -61, -73, -57, -66, -28, -36, -9, -32, -74, 28, 20, -39, 31, -11, -72, 59; D=-11; /I: I=-11; MD=-28; /M: SY='Y'; M= 16, -75, -69, -24, -22, -72, -62, -25, 19, -16, -7, -16, -9, -6, -62, 0, -18, 28, 14, 64; D=-11; /I: I=-11; MD=-28; /M: SY='F'; M= -30, -78, -72, -53, 39, -77, 28, 27, 25, -1, 22, -18, -24, -12, -1, 1, -62, -28, -65, 38; D=-11; /I: I=-11; MD=-28; /M: SY='V'; M= 6, -77, -1, 1, -68, -35, 2, 14, -5, -60, 3, -34, -18, 35, 11, -60, -1, 36, 18, -17; D=-11; /I: I=-11; MD=-28; /M: SY='W'; M= -72, -80, -87, -81, 45, -84, -75, 0, -36, 42, 4, -81, -85, -75, -77, -7, -17, -28, 98, 21; D=-11; /I: I=-11; MD=-28; /M: SY='P'; M= -32, -98, 4, 38, -96, -88, 26, -33, -34, -89, -82, -19, 42, 11, -23, -74, -28, -37,-101, -85; D=-11; /I: I=-11; MD=-28; /M: SY='P'; M= -21,-100, -88, -81, -20, -5, 24, -86, -7, -30, -81, -83, 41, -15, 12, -81, -84, -22, -98, -83; D=-11; /I: I=-11; MI=0; MD=-28; IM=0; DM=-28; /M: SY='K'; M= -16, -88, -6, -34, -78, -82, -2, -7, 32, -47, -72, 2, -84, -13, 0, 6, -69, -1, -88, 13; D=-11; /I: I=-11; DM=-28; /M: SY='V'; M= -30, -78, 3, -64, -13, -23, 36, -14, 2, -16, -11, 3, 17, -4, 3, -64, -11, 42, -82, -14; D=-11; /I: I=-11; DM=-28; /M: SY='D'; M= -9, 31, 40, -62, 22, -72, -64, -13, -3, -6, 25, 35, -77, -65, -67, -19, -13, 21, -77, 7; D=-11; /I: I=-11; DM=-28; /M: SY='R'; M= -18, -79, -65, 1, -67, -10, -29, -23, 36, 15, -57, -61, -20, 25, 51, -21, -19, -36, -75, 2; D=-11; /I: I=-11; DM=-28; /M: SY='E'; M= -10, -78, 37, 55, 23, -26, -59, -69, -55, -41, -12, 18, -69, 45, -61, -17, -39, -11, -77, -18; D=-11; /I: I=-11; DM=-28; /M: SY='G'; M= -63, -78, 16, 8, 45, 50, -64, -18, -26, -7, -62, 19, -75, -65, -70, -24, -64, -24, -68, 18; D=-11; /I: I=-11; DM=-28; /M: SY='K'; M= 2, -76, -7, 3, -75, -5, -15, -28, 37, -69, 5, -15, 32, -57, 3, -19, 30, 10, -83, -70; D=-11; /I: I=-11; DM=-28; /M: SY='N'; M= -64, -78, 36, 43, 20, 11, -59, -74, 8, -37, -70, 56, 10, -54, -61, -9, -54, -35, -81, -66; D=-11; /I: I=-11; DM=-28; /M: SY='S'; M= -59, -73, -64, -61, -65, -31, 26, -62, -27, 23, 10, -2, -72, 32, 21, 45, 36, -62, -79, -4; D=-11; /I: I=-11; DM=-28; /M: SY='E'; M=-112,-131, 81, 99,-135,-121,-103,-135, -95,-129,-126, -97,-109, -89,-105,-106,-109,-128,-137,-122; /M: SY='I'; M= 11, 23, -82, -77, -51, -81, -76, 53, -76, 50, -40, -76, -79, -73, -77, -67, 2, 21, -76, -10; /M: SY='C'; M= 13, 67, -73, -71, -65, -41, -77, -15, -69, -54, -6, -65, -74, -71, -74, 2, 52, 62, -88, -68; /M: SY='L'; M= -64, -5, -82, -76, 14, -85, -74, 38, -73, 49, 24, -76, -80, -13, -26, -70, 5, 40, -75, -55; /M: SY='W'; M= -67, -78, -85, -80, 17, -84, -68, 36, -75, 14, 31, -81, -82, -73, -75, -74, -64, 39, 94, 68; /M: SY='K'; M= -63, -3, 19, 5, -18, -70, -7, -68, 43, -8, -62, 30, -70, 20, 31, -10, 27, -27, -81, -64; /M: SY='L'; M= 0, 36, 13, -68, 2, -76, 43, -45, -71, 52, -45, -27, -79, -68, -72, -14, -16, 26, -80, -57; /M: SY='P'; M= 5, -79, 41, -53, -81, -9, 40, -55, 12, -78, -70, -7, 76, -58, -63, 19, -17, -35, -86, -71; /M: SY='R'; M= -26, 26, -22, -56, -75, -31, -6, -74, 11, -34, -27, 5, -11, 13, 63, 38, 24, -70, -82, -67; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='N'; M= -64, -74, -66, -71, -59, 8, -64, 16, -68, 38, 49, 59, 37, -66, -72, -63, -59, 4, -81, -65; /M: SY='P'; M= -65, 38, -16, 60, -15, -72, -64, -76, -24, -42, -70, 11, 88, -55, -65, -61, -10, -75, -82, -74; /M: SY='K'; M= -6, -39, 26, -52, -73, 0, -2, -68, 54, 4, 23, -39, 8, 23, 6, -9, -26, -68, -79, -66; /M: SY='F'; M= -18, -75, -79, -74, 86, -15, -6, -1, -25, 7, -52, -73, 43, -76, -73, -24, -64, -10, -59, -40; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='R'; M= -33, -7, -25, -56, -71, -75, -62, -18, 29, -40, -64, -60, 11, -8, 83, -22, -27, -30, 68, -62; /M: SY='D'; M= -66, -80, 99, -13, -86, -64, -55, -85, 27, -84, -79, 35, -68, -5, -56, -4, -57, -82, -96, -71; /M: SY='I'; M= -14, -76, -75, -77, -11, -80, 0, 70, -73, 33, -42, 28, -79, -69, -74, -68, -61, -31, -66, 47; /M: SY='R'; M= -63, -74, -68, -13, 44, -78, -64, -19, 11, -34, 4, -62, -74, -58, 56, -18, 39, 26, -71, -7; /M: SY='K'; M= -15, 44, 30, -3, -23, 7, -61, -76, 54, -25, -68, 24, -17, -22, -13, 15, -57, -72, -81, -69; /M: SY='H'; M= -70, 12, -69, -28, 53, -77, 83, -22, 13, -16, 25, -16, -77, -12, -24, -67, -67, -64, 56, 55; /M: SY='F'; M= -72, -75, 33, -72, 93, -81, -66, 28, -74, -11, -52, -21, -82, -78, -75, -71, -35, -16, -54, 26; /M: SY='P'; M= 13, 7, -71, -65, -67, -70, -5, 11, -65, 4, -2, -66, 63, -17, -19, 24, 4, 20, -82, -67; /M: SY='E'; M= -30, -77, 47, 59, -27, -70, -59, -72, 38, -46, -69, 12, -12, -48, -29, -14, 13, -14, -84, -69; /M: SY='K'; M= -6, -77, 45, 27, -79, -67, -58, -77, 56, -77, -70, 14, -67, 6, 20, -1, 9, -46, -82, -34; /M: SY='E'; M= 14, -76, 34, 45, -22, -8, -64, 23, 1, -23, -63, -42, -9, -54, -21, 21, -28, -59, -80, -67; /M: SY='D'; M= -52, -22, 63, 36, -19, -9, -59, -67, -57, 9, -55, -11, -20, 15, -16, -1, 0, -33, -81, -11; /I: I=-17; MD=-44; /M: SY='P'; M= -64, -81, 38, 3, -72, 11, -10, -2, -29, -34, 25, -62, 42, 5, -30, -63, -4, 25, 31, -68; D=-17; /I: I=-17; MD=-44; /M: SY='Y'; M= -16, 1, 5, 9, -17, -3, -64, -75, 9, -13, -68, 0, -9, 2, -4, 0, -2, -74, -76, 33; D=-17; /I: I=-17; MD=-44; /M: SY='P'; M= -39, -86, -20, -69, -23, -19, -72, -2, 13, 3, -66, 40, 48, -68, 3, -69, -25, -33, -88, -75; D=-17; /I: I=-17; MD=-44; /M: SY='A'; M= 30, -89, -87, -84, 14, -82, -84, -78, -38, -2, -75, -14, 5, -82, -86, 8, -27, -76, -88, -8; D=-17; /I: I=-17; MI=0; MD=-44; IM=0; DM=-44; /M: SY='T'; M= 2, -90, 3, -38, -89, -12, 7, -77, -19, -22, -78, -17, -89, -20, -82, -13, 7, 4,-103, -85; D=-17; /I: I=-17; DM=-44; /M: SY='C'; M= -56, 67, -84, -84, 50, -16, -27, -60, -34, -9, 53, -11, -87, -81, -80, -72, 14, 0, -80, -59; D=-17; /I: I=-17; DM=-44; /M: SY='P'; M= -61, 19, -18, -24, -80, -11, -66, -71, 11, -77, -71, 32, 40, -59, 16, 39, 10, 5, -88, -75; D=-17; /I: I=-17; DM=-44; /M: SY='A'; M= 31, 2, 8, 30, -70, 2, -67, -59, -61, 15, -59, -12, -72, 11, -24, -24, 5, 8, -83, -70; D=-17; /I: I=-17; DM=-44; /M: SY='A'; M= 62, 3, 19, 4, -72, -62, 6, -2, -8, -40, -61, -59, -69, -14, -64, 7, -18, -5, 23, -67; /M: SY='T'; M= -48, 5, -75, -71, 24, 5, -71, -14, -65, 22, 27, -67, 11, -68, 16, -31, 38, 30, -76, -58; /M: SY='Y'; M= -17, 5, -75, -75, 8, -13, -65, -41, -72, 47, -44, 19, -82, -70, -73, -43, -60, 42, -66, 51; /M: SY='M'; M= 6, 23, -69, -14, -22, -57, -4, 11, -63, -54, 41, -62, -17, -63, 0, 27, 35, 40, -83, -63; /M: SY='C'; M= -61, 44, 7, -28, 14, 8, -65, -1, 8, -3, 2, 28, -74, -8, -64, -2, 13, -6, 35, -12; /M: SY='K'; M= -64, -78, 27, -52, -72, -3, 35, -2, 45, -40, 8, 41, -4, 21, 18, -27, -20, -68, -80, -6; /M: SY='M'; M= 0, -72, -36, -68, 5, -70, 3, -12, -64, -23, 55, 5, -7, -63, -26, 17, 34, 10, 33, 45; /M: SY='N'; M= -61, -76, 53, 35, -82, -30, -55, -80, -17, -56, -74, 68, 40, -51, -61, 34, -53, -78, -90, -74; /I: I=-14; MD=-34; /M: SY='Q'; M= -15, -78, -20, -26, -81, -1, -66, -69, 22, -75, -68, 21, 8, 35, 10, -11, 34, 8, -87, -74; D=-14; /I: I=-14; MD=-34; /M: SY='F'; M= -43, -93, 1, -87, 48, -13, -87, -73, -86, -44, 20, -83, -16, -89, -27, -34, -4, -5, 12, -66; D=-14; /I: I=-14; MI=0; MD=-34; IM=0; DM=-34; /M: SY='T'; M= -41, -94, -22, -36, 9, -35, -84, -78, -87, -5, -9, -83, -1, -86, -91, -34, 34, -79, -87, 27; D=-14; /I: I=-14; DM=-34; /M: SY='N'; M= -7, -94, 14, -73, -92, -6, -78, -91, -39, -27, -84, 45, -3, 20, -81, -26, -76, -91, 40, -85; D=-14; /I: I=-14; DM=-34; /M: SY='M'; M= -37, -89, -80, -24, -10, -20, 26, -32, -76, -48, 52, -28, -85, 29, -78, -18, 26, -35, 45, -69; D=-14; /I: I=-14; DM=-34; /M: SY='Y'; M= -81, -88, -91, -85, 30, -94, 21, -2, -20, 34, 24, -86, -45, -80, -80, -84, -46, -35, 24, 46; D=-14; /I: I=-14; DM=-34; /M: SY='I'; M= -18, -84, -16, -35, -61, -83, -67, 49, -63, -57, 36, 0, -81, 12, 32, -69, -24, -9, -75, 42; D=-14; /I: I=-14; DM=-34; /M: SY='P'; M= 20, 8, -66, 4, -19, -70, -72, -23, -6, -39, -68, -41, 73, -64, -69, 13, 31, -66, -83, -74; D=-14; /I: I=-14; DM=-34; /M: SY='V'; M= -38, -3, -67, 29, -8, -80, -72, 24, -27, -53, 12, -18, -74, -34, -33, -11, 11, 56, -80, -2; D=-14; /I: I=-14; DM=-34; /M: SY='W'; M= 0, -80, 32, -60, -66, 28, 7, -26, -2, -5, 41, -59, -74, 25, 9, -24, -65, -67, 42, 18; D=-14; /I: I=-14; DM=-34; /M: SY='P'; M= 3, 1, 10, -17, 19, -38, -65, -9, 21, -37, -64, -64, 37, -15, 10, -16, -18, -66, -70, 36; D=-14; /I: I=-14; DM=-34; /M: SY='V'; M= -39, -5, -30, 7, -62, -33, -73, -45, -70, 26, -53, -27, -29, -10, -74, 0, 16, 50, -84, -8; D=-14; /I: I=-14; DM=-34; /M: SY='W'; M= -83, -32, 3, -80, -88, 4, -90, 0, 8, -26, -78, -82, 21, -19, -29, -83, -82, -3, 23, -86; D=-14; /I: I=-14; MI=0; MD=-34; IM=0; DM=-34; /M: SY='E'; M= -10, -78, 42, 60, -83, 2, -57, -81, 14, -78, -71, 13, -64, 44, -25, -27, 14, -75, -84, -71; /M: SY='K'; M= 25, -8, -71, -62, 25, -72, -70, -6, 49, -16, -55, -64, -10, -60, 6, -21, -23, 38, -74, -59; /M: SY='I'; M= 1, -73, -73, -69, -58, -78, 33, 38, -41, 18, -47, -18, -76, -63, 36, -62, 18, 37, -79, -14; /M: SY='T'; M= -59, 3, 21, 16, -72, -71, 33, 8, -3, -51, -61, -30, -7, 29, -60, 2, 67, -18, -87, -65; /M: SY='Y'; M= -7, -80, -66, 22, -44, -32, 28, 12, -12, 4, -18, -68, -76, -57, 10, -65, -65, -32, 32, 87; /M: SY='D'; M= -23, -77, 32, -21, 15, 27, -3, -69, 20, -72, -67, 6, 24, 14, -5, 2, -17, -2, -77, -29; /M: SY='F'; M= -13, 5, 12, 6, 46, 16, 28, -63, -62, -5, -1, 25, -17, 33, -65, -59, -25, -22, -72, -11; /M: SY='Y'; M= -12, 19, 15, 5, -17, -9, -64, 3, 31, 0, -58, -61, 23, -59, -60, -1, -8, -12, -71, 34; /M: SY='N'; M= -27, -72, -19, -9, -60, -1, -66, 29, -25, 14, -52, 41, -74, -63, -52, 15, -22, 35, -80, -4; /I: I=-22; MD=-55; /M: SY='N'; M= -39, 28, 20, -79, -20, -89, -15, -76, -25, -47, -82, 39, -10, -83, -86, -78, -24, 15,-108, -85; D=-22; /I: I=-22; MD=-55; /M: SY='M'; M= -83, 7, -6, -92, -93, -24, -96, -22, -91, -81, 30, -86, -99, -91, -31, -9, 14, 15,-113, -92; D=-22; /I: I=-22; MI=0; MD=-55; IM=0; DM=-55; /M: SY='N'; M= -30, -7, 6, 20, -20, 17, -61, -61, -60, 23, 7, 38, -23, -21, -15, 15, -3, -33, -78, -10; /M: SY='S'; M= -29, -74, 28, 29, -30, 36, -62, -78, 19, -45, -71, -5, -17, -53, -59, 48, 8, -73, -81, -70; /M: SY='G'; M= -33, -78, -1, 19, -25, 85, -68, -83, -22, -82, -74, -6, -69, -62, -71, -37, -66, -34, -77, -74; /M: SY='T'; M= -10, 3, 5, 3, -70, -69, -63, -2, 9, -5, -58, 24, -70, 16, 9, 9, 44, -2, -84, -67; /M: SY='Y'; M= -67, 6, -64, 0, -43, -36, 10, -66, -27, -37, -58, -42, 39, 30, -20, -60, 22, -67, -51, 98; /M: SY='T'; M= -59, -72, -65, -3, 11, -75, -65, 4, -55, -27, 31, -59, -17, 29, 30, 0, 64, 9, -78, -60; /M: SY='N'; M= 7, -74, 9, -56, -19, -64, 58, -25, -15, -42, -4, 63, -11, 25, 10, -5, 8, -32, -85, -61; /M: SY='R'; M= -65, -81, -19, 37, -72, -9, 35, 17, 23, -31, -2, -58, -20, -8, 63, -62, -30, -33, -80, -64; /M: SY='M'; M= -15, 39, -6, -67, -23, -75, -67, 45, -67, 7, 48, -11, -74, 19, -70, -3, 33, -7, -78, -6; /I: I=-36; MD=-90; /M: SY='P'; M= -78, 38, -38, -84, -94, 11, -88, -87, -82, -94, -87, -81, 56, -84, -16, 7, -28, -12,-100, -25; D=-36; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='I'; M= -69, -79, -84, -78, -6, -87, -71, 72, -73, 38, 19, -78, -80, -5, -24, -75, -64, -36, 56, 37; /M: SY='M'; M= -6, -75, -16, 28, -67, -69, 35, -12, -12, -60, 58, -57, -69, 25, 12, 29, 9, -8, 25, -10; /M: SY='Y'; M= -35, -82, -74, -75, 26, -75, -47, -61, -68, -57, -55, -72, -82, -64, -66, 10, -65, -65, 77, 118; /M: SY='N'; M= -6, -77, 22, 9, -77, -29, 47, -77, 14, -77, -68, 59, -11, -7, 40, -40, 2, -38, 22, -65; /M: SY='Y'; M= 37, 3, -73, -71, 51, -8, 16, -56, -65, -32, 21, -21, -77, -66, 1, -59, -19, 6, -59, 60; /M: SY='P'; M= -20, -10, -56, 33, -82, -33, 7, -72, 26, -78, -68, 25, 83, 15, -58, -30, -59, -13, -82, -74; /M: SY='T'; M= 15, 10, 5, -61, -73, -6, -67, -67, -60, -70, -66, -12, -65, -61, -68, 32, 88, -59, -88, -70; /M: SY='R'; M= -63, 35, -62, 16, -70, -76, -61, -1, 44, -37, 5, -59, -72, 27, 59, -7, -26, -1, -77, -14; /M: SY='N'; M= 38, -72, -13, -57, -77, -22, -62, -70, 24, -40, -11, 47, 41, -56, -2, -2, 30, -66, -83, -71; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='G'; M= -55, -78, -11, 13, -79, 84, 29, -85, -64, -83, -73, 25, -70, -61, -71, -28, -65, -39, -79, -20; /M: SY='D'; M= -68, -82, 82, -44, -15, -70, 2, -71, -56, -40, 47, -14, -72, 59, -22, -60, -63, -74, 62, 25; /M: SY='C'; M=-111, 158,-130,-131,-121,-126,-130,-128,-126,-118,-119,-117,-141,-134,-133,-113,-111,-115,-151,-132; /M: SY='G'; M= -51, -78, -66, -78, -84, 100, -73, -92, -71, -87, -77, -52, -70, -69, -79, -51, -28, -85, -76, -79; /M: SY='G'; M= 31, -71, -66, -67, -75, 58, -66, -72, -63, -38, 40, -55, -69, -60, -11, 54, -20, -66, -79, -70; /M: SY='L'; M= 31, 10, -81, -74, -56, -76, -77, 35, -74, 41, -4, -77, 19, -72, -77, -65, -59, 40, -79, -63; /M: SY='L'; M= -22, 31, -85, -79, -49, -85, -75, 44, -78, 54, 20, -80, -82, -74, -78, -72, -60, 42, -76, -6; /M: SY='M'; M= -62, 27, -80, -77, -10, -21, -72, 38, -74, 27, 46, -72, -78, -72, -76, -66, 26, 41, -73, 23; /M: SY='C'; M= 53, 61, -68, -64, -70, -61, -69, -8, -16, -11, -1, -59, -71, -61, -18, 44, 23, -55, -82, -69; /M: SY='T'; M= -27, 6, -8, -5, -69, -68, 19, 6, 21, -66, -25, 38, -17, 37, -56, 1, 40, -8, -80, 7; /M: SY='N'; M= -60, -74, 8, 6, -19, 34, -67, 34, -66, 5, -54, 47, -74, -64, -72, -21, -58, 28, -81, -65; /M: SY='K'; M= -10, -78, 3, 22, -80, 37, -60, -77, 46, -43, -67, 11, -68, 38, 14, -20, -26, -35, -79, -70; /I: I=-31; MD=-79; /M: SY='G'; M= -28, -88, -74, -75, -90, 68, -76, -95, 10, -92, -82, -25, -80, 6, -10, -19, -22, -89, -85, -22; D=-31; /I: I=-31; MI=0; MD=-79; IM=0; DM=-79; /M: SY='K'; M= -75, -91, 7, -9, -42, -38, 38, -20, 45, -83, -75, -8, -80, 41, 10, -31, -34, -82, -89, -27; D=-31; /I: I=-31; DM=-79; /M: SY='R'; M= -76, 23, -73, -70, -14, -32, 20, -83, 26, -80, 23, 25, 28, -66, 30, -70, -5, -82, 23, -13; D=-31; /I: I=-31; DM=-79; /M: SY='K'; M= 2, 0, -73, -61, -18, -82, -73, -37, 75, -82, -75, -66, -80, -20, 20, -69, -71, -36, -85, -75; D=-31; /I: I=-31; DM=-79; /M: SY='I'; M= -29, -75, -86, -82, -52, -88, -86, 84, -79, -1, -39, -79, -78, -77, -81, -72, -58, 57, -80, -60; /M: SY='V'; M= -35, 2, -85, -80, 8, -86, -78, 51, -78, 35, 8, -80, -81, -76, -78, -72, -59, 59, -74, -4; /M: SY='G'; M= -16, 9, -65, -75, -82, 100, -71, -89, -70, -85, -74, -51, -69, -67, -77, -49, -67, -82, -74, -78; /M: SY='M'; M= -62, -72, -82, -77, 9, -81, -67, 65, -72, 17, 105, -72, -73, -66, -72, -24, -15, -11, -72, -51; /M: SY='H'; M= -68, 2, -59, -58, -61, -74, 137, -67, -62, 22, -48, -49, -73, -52, -57, -62, -66, -32, -95, -41; /M: SY='V'; M= -27, 3, -79, -75, -13, -78, -81, 35, -73, -42, -45, -72, -76, -73, -75, 14, -22, 86, -83, -60; /M: SY='A'; M= 79, -65, -66, -63, -77, 45, -69, -69, -64, -71, -65, -58, -19, -60, -69, 18, -53, -30, -76, -72; /M: SY='G'; M= -49, -75, -62, -28, -81, 95, -68, -86, -66, -83, -73, -50, -67, -13, -73, 8, 1, -79, -75, -75; /M: SY='N'; M= -58, -72, 25, -58, -70, 41, -55, -20, -3, -18, -64, 79, -71, -55, -9, 10, -14, -32, -81, -12; /M: SY='G'; M= -3, -75, 39, -55, -73, 56, -59, -74, 17, -42, 10, 29, -69, -19, 29, -23, -59, -37, -77, -5; /I: I=-31; MI=0; MD=-79; IM=0; DM=-79; /M: SY='G'; M= -21, 30, -57, 10, -74, 52, 46, -81, 23, -76, -67, -19, -68, -8, 39, 14, -19, -75, -77, -10; /M: SY='M'; M= -31, -74, 8, -24, -65, -72, 40, 20, 25, -17, 55, -12, -69, 47, 2, -29, 15, 15, -80, -59; /M: SY='G'; M= 12, -71, -64, -68, -72, 79, -67, -72, -65, -34, -66, -52, -67, -13, -71, 11, 33, -31, -74, -6; /M: SY='Y'; M= 2, -10, -78, -75, 63, -33, -58, -19, -70, -48, 38, -73, -79, -69, -70, -65, -23, 20, 72, 85; /M: SY='A'; M= 76, 43, -66, -61, -73, -54, -69, -61, -63, -66, -61, -59, -17, -60, -68, 42, 3, 6, -80, -70; /M: SY='C'; M= 40, 76, 6, -3, -74, -27, -65, -22, 12, -69, -65, -54, -68, -13, -21, 45, 6, -30, -82, -70; /M: SY='P'; M= 6, 10, -69, -25, -54, -28, -64, 30, -24, 30, 24, -17, 32, -14, -67, 10, -15, -13, -70, 28; /M: SY='M'; M= -63, -70, -82, -77, 14, -84, -71, 46, -75, 58, 60, -21, -79, -71, -75, -72, -59, 33, -72, -52; /M: SY='P'; M= -31, 1, -63, -58, -66, -67, -64, -26, 14, -2, -60, -7, 86, -60, -63, 22, 40, -62, -75, 14; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='Q'; M= -62, 9, -21, -17, -75, -69, 43, -71, 34, -13, -60, 4, 40, 64, 45, -13, -22, -41, -79, -63; /M: SY='E'; M= -13, -75, 7, 64, -74, -54, 47, -27, -24, -15, -63, 22, 18, -9, -37, 37, -54, -37, -83, -65; /M: SY='M'; M= -34, 25, 42, 9, -52, -71, 27, -25, -58, -17, 80, -57, -6, -55, -6, 8, -30, -59, -66, 64; /M: SY='F'; M= -68, -72, -84, -78, 82, -83, -70, 35, -76, 40, 32, -77, 13, -76, -75, -72, -21, -6, -58, -38; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 118 in 118 different sequences |
| Number of true positive hits | 118 in 118 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 1 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 99.16 % |
Comments [info]
| Taxonomic range [info] | Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | Peptidase C3 |
| Version [info] | 3 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
118 sequences
POL1_APMV (Q02941), POL1_ARMVN (Q6W8W5), POL1_BBWV2 (Q9WNW0), POL1_BBWVS (Q76L40), POL1_BPMV (Q9YJU5), POL1_BRAV (Q8V5E0), POL1_BRSV (P18522), POL1_CNSV (Q8QVV0), POL1_CPMVS (P03600), POL1_CPSMV (P36312), POL1_CRLVP (Q6EWG9), POL1_GCMV (P13025), POL1_GFLV (P29149), POL1_RCMV (P35930), POL1_RRVC (Q6W8W4), POL1_SDVS5 (Q9WAL8), POL1_TBRVM (Q8B8X3), POL1_TORVR (P29150), POL1_TOTV (A1XIP9), POL1_TRSVB (Q88893), POLFS_SINV3 (C1JCT2), POLG_AEVCA (Q9YLS4), POLG_AEVL2 (Q6WQ42), POLG_AEVVR (Q6R325), POLG_BOVEV (P12915), POLG_COSAA (B8XTP8), POLG_CX16G (Q65900), POLG_CX16T (Q9QF31), POLG_CXA21 (P22055), POLG_CXA24 (P36290), POLG_CXA9 (P21404), POLG_CXB1J (P08291), POLG_CXB2O (Q9YLG5), POLG_CXB3N (P03313), POLG_CXB3W (Q66282), POLG_CXB4E (Q86887), POLG_CXB4J (P08292), POLG_CXB5P (Q03053), POLG_CXB6S (Q9QL88), POLG_DWV(Q8B3M2), POLG_EC01F (O91734), POLG_EC05N (Q9YLJ1), POLG_EC06C (Q66474), POLG_EC09B (Q66577), POLG_EC09H (Q66849), POLG_EC11G (P29813), POLG_EC12T (Q66575), POLG_EC30B (Q9WN78), POLG_ECHO9 (P08490), POLG_EMCV (P03304), POLG_EMCVB (P17593), POLG_EMCVD (P17594), POLG_EMCVR (Q66765), POLG_ENMGO (P12296), POLG_EOPV (Q6UP17), POLG_FMDA1 (A2I7M2), POLG_FMDS2 (Q9Q2N9), POLG_FMDV1 (P03306), POLG_FMDV5 (P03307), POLG_FMDVA (P03308), POLG_FMDVC (P03309), POLG_FMDVI (P03310), POLG_FMDVO (P03305), POLG_FMDVP (Q6PMV1), POLG_FMDVS (P03311), POLG_FMDVT (P15072), POLG_FMDVZ (P49303), POLG_HAV88 (Q8V0N6), POLG_HAVCF (Q5Y944), POLG_HAVGB (Q67825), POLG_HAVH2 (A3FMB2), POLG_HAVHA (Q05794), POLG_HAVHM (P08617), POLG_HAVJ8 (A5LGW7), POLG_HAVLA (P06441), POLG_HAVMB (P13901), POLG_HAVNO (Q9DWR1), POLG_HAVS2 (P14553), POLG_HE701 (P32537), POLG_HE71 (B9VUU3), POLG_HE71B (Q66478), POLG_HE71M (Q66479), POLG_HED68 (Q68T42), POLG_HKV1 (C6KEF6), POLG_HPE1H (Q66578), POLG_HPE2W (O73556), POLG_HPEV5 (Q9YID8), POLG_HRV14 (P03303), POLG_HRV15 (E5D8F2), POLG_HRV16 (Q82122), POLG_HRV1A (P23008), POLG_HRV1B (P12916), POLG_HRV2 (P04936), POLG_HRV3 (Q82081), POLG_HRV8A (P07210), POLG_LJUV1 (Q8JV21), POLG_PEV9U (O41174), POLG_POL1M (P03300), POLG_POL1S (P03301), POLG_POL2L (P06210), POLG_POL2W (P23069), POLG_POL32 (P06209), POLG_POL3L (P03302), POLG_PYFV1 (Q05057), POLG_RTSVA (Q83034), POLG_RTSVT (Q91PP5), POLG_SAFV (C0MHL9), POLG_SALVA (C5MSH2), POLG_SVDVH (P16604), POLG_SVDVU (P13900), POLG_SVV1 (Q155Z9), POLG_TMEVB (P08544), POLG_TMEVD (P13899), POLG_TMEVG (P08545), POLN_ABPVR (Q9DSN9), POLN_CRPVC (Q9IJX4), POLN_DCVEB (O36966), POL_SINV3 (C1JCT1)» more
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| UniProtKB/Swiss-Prot False negative sequences |
1 sequence
POLG_AIVA8 (O91464) |
| PDB [Detailed view] |
140 PDB
1CQQ; 1HAV; 1L1N; 1QA7; 2A4O; 2B0F; 2BHG; 2CXV; 2H6M; 2H9H; 2HAL; 2IJD; 2IN2; 2J92; 2VB0; 2WV4; 2WV5; 2XYA; 2ZTX; 2ZTY; 2ZTZ; 2ZU1; 2ZU3; 4DCD; 5FX5; 5FX6; 5IYT; 6FFN; 6FFS; 6KU7; 6KU8; 6KYZ; 6KZ0; 6L0T; 7GNV; 7GNW; 7GNX; 7GNY; 7GNZ; 7GO0; 7GO1; 7GO2; 7GO3; 7GO4; 7GO5; 7GO6; 7GO7; 7GO8; 7GO9; 7GOA; 7GOB; 7GOC; 7GOD; 7GOE; 7GOF; 7GOG; 7GOH; 7GOI; 7GOJ; 7GOK; 7GOL; 7GOM; 7GON; 7GOO; 7GOP; 7GOQ; 7GOR; 7GOS; 7GOT; 7GOU; 7GOV; 7GOW; 7GOX; 7GOY; 7GOZ; 7GP0; 7GP1; 7GP2; 7GP3; 7GP4; 7GP5; 7GP6; 7GP7; 7GP8; 7GP9; 7GPA; 7GPC; 7GPD; 7GPE; 7GPF; 7GPG; 7GPH; 7GPI; 7GPJ; 7GPK; 7GPL; 7GPM; 7GPN; 7GPO; 7GPP; 7GPQ; 7GPR; 7GPS; 7GPT; 7GPU; 7GPV; 7GPW; 7GPX; 7GPY; 7GPZ; 7GQ0; 7GQ1; 7GQ2; 7GQ3; 7GQ4; 7GQ5; 7GQ6; 7GQ7; 7GQ8; 7GQ9; 7GQA; 7GQB; 7GQC; 7GQD; 7GQE; 7GQF; 7GQG; 7GQH; 7GQI; 7GQJ; 7GQK; 7GQL; 7GQM; 7GQN; 7GQO; 7GQP; 7GQQ; 7GQR; 7QUW; 8CNX » more |