PROSITE entry PS51893
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS51893 |
| Entry name [info] | AKAP_CAM_BD |
| Accession [info] | PS51893 |
| Entry type [info] | MATRIX |
| Date [info] |
05-JUN-2019 CREATED;
05-JUN-2019 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51893 |
| Associated ProRule [info] | PRU01241 |
Name and characterization of the entry
| Description [info] | A kinase-anchoring proteins AKAP-5 and AKAP-12 calmodulin (CaM)-binding motif profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=21; /DISJOINT: DEFINITION=PROTECT; N1=3; N2=19; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6058626; R2=0.0075913; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=975; N_SCORE=10.0; MODE=1; TEXT='R'; /CUT_OFF: LEVEL=-1; SCORE=513; N_SCORE=6.5; MODE=1; TEXT='R?'; /DEFAULT: M0=-66; D=-20; I=-20; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-105; BD=-105; /M: SY='E'; M= -29,-127, 53, 58,-105, 28,-111, 3, 16, -83,-114,-102,-115, -7, -14, -64, -42, 7,-131,-119; /M: SY='S'; M= -99,-121, -77, 44,-127, 59,-112, -54, -52, -91, -32,-100, -91,-102, -65, 71, 1, -75,-129,-120; /M: SY='T'; M= 68,-112,-110,-107,-120, -76, -53,-109,-108,-115,-109, -59, 33,-107,-114, 38, 70, -17,-129,-117; /M: SY='W'; M=-123,-148,-150,-128, -88,-122,-150, -17,-120,-116,-119,-143,-127,-120,-124,-130,-134,-129, 183, -75; /M: SY='A'; M= 72,-114, 5, 10, -62, -36,-114,-102, 6, -81,-107, -51,-115, -38, -55, -4, -17, 41,-127,-115; /M: SY='S'; M= 24,-112,-105,-105,-121,-100,-110,-117,-105,-121,-115, -95, 9,-100,-111, 99, 47,-109,-130,-115; /M: SY='F'; M=-117,-120,-134,-129, 95,-133,-120, 64,-126, 43, -87,-126,-129,-127,-125,-122,-111, -60,-103, -83; /M: SY='K'; M=-111,-126,-104, -90,-126,-118,-104,-127, 109,-125,-113, -97,-112, -20, 50,-105,-106,-123,-120,-112; /M: SY='K'; M=-111, -25,-104, -95,-125, -60, -17,-128, 85,-125,-113, 28,-116, -89, 84, -40,-106,-123,-124,-112; /M: SY='L'; M=-115,-117,-132,-124, 40,-132,-114, -42,-122, 86, 58,-128,-130,-118, -33,-123,-111, -89,-114, -95; /M: SY='V'; M= -17,-115,-129,-123,-101,-128,-126, 37,-120, -42, 59,-122,-123,-120,-122,-112, -10, 92,-131,-107; /M: SY='T'; M= -76,-116,-109,-107,-117,-117,-113, -56, -58,-110, 45, -77, 61,-107, 25, -71, 102,-103,-131,-114; /M: SY='P'; M= -68, -42,-112,-105,-129, 36, 46,-126,-102,-116,-116,-109, 106, -78, 44, -18,-108,-126,-127,-120; /M: SY='R'; M=-114,-130,-108, -96,-128,-122,-104,-101, 77,-126,-114, -35,-119, 26, 91, -54, -76,-125,-124,-114; /M: SY='R'; M=-114,-128,-107, -97,-127,-121,-105,-130, 84,-127,-115, 6,-118, -91, 87, -55, -39,-125,-125,-114; /M: SY='K'; M=-115,-129,-108, -97,-126,-122, 50,-106, 83, -80,-113, -70, -76, -80, 83, -56, -73,-125,-126,-111; /M: SY='S'; M= 27,-120, -66,-103,-122, -95, -43, -58, 45, -51, -29, -23, 17, 37, -34, 51, -33, 19,-128,-116; /M: SY='K'; M=-113,-128, 6, -17,-129, -69, -21,-130, 99,-128,-117, -44,-115, -91, 49, -65, -92,-126,-125,-115; /M: SY='S'; M= -8,-119, -2, -74, -91, -77, -62, -98, -38, -54, -54, -31, 10, -77, 44, 83, 19,-115,-131,-116; /M: SY='S'; M= -23, -47, 53, 47,-104, -74, -73,-124, -12, -47,-120, -64, 22, -86, -33, 70, -72, -68,-134,-119; /M: SY='S'; M= -34,-122, 15, 38, -61, 32,-110, -93, 25, -30, -16, -86, -89, -38, -45, 65,-102, -67,-129,-118; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 13 in 7 different sequences |
| Number of true positive hits | 13 in 7 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 3 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | MOTIF |
| Feature description [info] | AKAP CaM-binding |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
7 sequences
AKA12_HUMAN (Q02952), AKA12_MOUSE (Q9WTQ5), AKA12_RAT (Q5QD51), AKAP5_BOVIN (P24275), AKAP5_HUMAN (P24588), AKAP5_MOUSE (D3YVF0), AKAP5_RAT (P24587)» more
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| PDB [Detailed view] |
1 PDB
5NIN |