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PROSITE entry PS51901


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General information about the entry

Entry name [info] ACP_MB
Accession [info] PS51901
Entry type [info] MATRIX
Date [info] 16-OCT-2019 CREATED;
07-APR-2021 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51901
Associated ProRule [info] PRU01249

Name and characterization of the entry

Description [info] Archaeal CBS proteins (ACP)-type metal binding (MB) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=35;
/DISJOINT: DEFINITION=PROTECT; N1=4; N2=32;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.0344079; R2=0.0088734; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=3595.0000000; R2=0.0000000; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1124; H_SCORE=3595; N_SCORE=13.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=391; H_SCORE=3595; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-132; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='P';  M= -42,-421,  14,  26,  20, -34,   2,   4,   1, -33,  18, -39,  41, -33, -53,  25,   9,  -2, -96,  19;
/M: SY='Y';  M= -62,-419, -10,  24,  20, -33,  -2,  27, -13,  -2, -24, -13,-109, -16, -29,   6,  35,   8,-415,  41;
/M: SY='Q';  M=  -2,-421,   2,  58,-104, -46, -26, -62,   4,-142, -24, -18, -19,  70, -30,  26,  17, -53, -44,  -4;
/M: SY='G';  M= -82,-423,-163,-419, -18, 102,  25,-431,-414,-427, -85, -61, -29,-411,-420,  -6,-411,-427,-418,  -6;
/M: SY='I';  M=-161,-145,-421, -19, -16,-429,  11,  74, -27, -11,  20, -46,-101,-131, -23,-128, -56,  46,-412,  59;
/M: SY='C';  M=-408, 162,-428,-428,-418,-423,-428,-425,-423,-415,-416,-414,-438,-431,-430,-410,-408,-412,-448,-429;
/M: SY='E';  M=-138,-428,  68,  98,-431,-127,-401,-429,-166,-425,-420, -65,  39,  17,-402, -48,-116,-424,-431,-419;
/M: SY='S';  M=  -8,-419, -16,  37,-114, -89,  -3,  17,  27, -44, -95,  17,-414, -60,  28,  39, -36,  26,-425, -34;
/M: SY='C';  M=-408, 162,-428,-428,-418,-423,-428,-425,-423,-415,-416,-414,-438,-431,-430,-410,-408,-412,-448,-429;
/M: SY='G';  M= -85, -26, -57,   8,-164,  97,-101,-430,-129,-145,  11,  15,-414, -39, -19, -25,-410,-425,-423,-160;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='N';  M=  21, -81, -69,  33,-110,  19, -47, -70, -27,-110, -33,  59,-413,  37,   9,  16,  15, -13,-425, -32;
/M: SY='Y';  M= -94,-423,-151,-152,  43,-176, -28,  -4, -25,  19,  32,-184, -14,   0, -49,-414, -15,  -5,  89,  90;
/M: SY='S';  M=   6,-104,  17,-103, -96,   6,-409,-206, -67,  -9,  20,-103,-414,-105, -22,  86,   6,  -4,-427,-107;
/M: SY='D';  M= -54,-423,  67,  63, -85,-116, -41, -26, -20, -31, -86, -35,  21,   0,  -3, -11,   8, -19,-428, -19;
/M: SY='D';  M= -28,-421,  63,   2,-111,-104,-300, -83, -40,  22, -43,  45,  48, -34, -18,   4, -15, -25,-428, -19;
/M: SY='L';  M=-411,-417,-126, -50, -87,-429, -49, -25,-159,  85,-110, -23,-149,-414, -50, -61, -88,  27,-415,  31;
/M: SY='Y';  M= -39, -12, -34,  -2, -54,-117, -42, -38,  43, -47, -12, -31,-418,   0,  36,   2,  -6,  39,  -8,  61;
/I:         I=-21; MI=0; MD=-53; IM=0; DM=-53;
/M: SY='N';  M= -87,-134,   2,  43,  -1,-420, -47, -76, -56, -19, -30,  54, -27,   7,   3,  16, -28, -70,   1,  21; D=-21;
/I:         I=-21; DM=-53;
/M: SY='V';  M=  17,-418,   8, -17,   6, -88, -12,  45, -21, -50, -34, -65,-419, -13, -72, -24, -56,  62, -83,  27;
/M: SY='N';  M= -78,-423,  70,  26,-425,  -7, -72,-428,  21,-428,-420,  87,-416, -24,   4, -99,-403,-426,-433,  -6;
/M: SY='G';  M=-140,-423, -40, -75,-430, 102,-414,-436, -71,-433,-423,  35,-416,-118,-420, -23,-412,-431,-424,-424;
/I:         I=-22; MI=0; MD=-57; IM=0; DM=-57;
/M: SY='Q';  M=-109,-423,-156, -13,  -6, -59, -83, -49,  45,  -1,  49, -28, -63,  57,  39, -23, -37,  25,-421, -49;
/M: SY='W';  M= -46,-422,-426,-422,  67,-424,-410, -91, -44,  40,  48,   5,-132,-416,-104, -41, -52, -59,  93,  63;
/M: SY='L';  M= -80,-420,-429,-422, -84,-432, -99,  47, -29,  60,  -6,-424,-427,-416,  16,-419, -69,  50,-423, -42;
/M: SY='C';  M=-410, 160,-430,-430,-420,-426,-430,-427,-426,-418,-418,-416,-441,-434,-432,-413,-410,-415,-450,-431;
/M: SY='E';  M= -15,-426,  23,  78,-427, -30,-137, -34, -21,-123,-122,  -9,  43, -61,  -9,  24, -50,-100,  -9,-123;
/M: SY='D';  M= -63,-423,  68,  42, -86, -99,  -5,-425, -14,-144,-116,  64,-415, -31,  22,  27, -53, -41,-436,-127;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='C';  M=-410, 160,-430,-430,-420,-426, -81,-427,-426,-418,-418,-416,-441,-433,-432,-413,-410,-415,-450,-431;
/M: SY='R';  M=  -8,-427,  -5, -75,-113,  -7,-101, -13,  27, -64,  26, -78,-421, -33,  91, -51,-116, -76, -90,   0;
/M: SY='D';  M= -28,-426,  67,  64,-419, -20,  25, -75, -15,-105, -86, -16,-103, -40, -30, -13, -13, -60,-426,  35;
/M: SY='E';  M= -27,-425,  20,  76,  -5, -28,-409, -10, -56, -53,  44, -27,-415, -44, -67,   8, -41,  -8,-427, -54;
/M: SY='E';  M= -87,-432, -29,  57, -34, -42, -21,  -3, -29,  26,  27, -73,-425,   5, -21, -17, -80, -57, -81, -47;
/M: SY='E';  M= -71,-445,   4,  38,-112,   4, -65, -86,-133, -66, -56, -46, -80, -21, -15, -12, -31, -24, -60, -10;
/M: SY='E';  M= -74,-451,  -8,  15, -99,  -2,-435, -29, -25, -31, -88,-121, -89, -53, -13,   4, -54, -92,-448,  -1;
/M: SY='E';  M=-119,-461, -15,  25, -57, -61,-441,-137,   5, -67, -37, -60, -60, -50, -50, -23, -61,-112,-457, -13;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 2 in 2 different sequences
Number of true positive hits 2 in 2 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Archaea
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] ACP-type MB
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
2 sequences

Y525_METKA  (P50100), Y653_METJA  (Q58069)