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ProRule PRU01249


General rule information [?]

Accession PRU01249
Dates 7-AUG-2019 (Created)
19-NOV-2022 (Last updated, Version 5)
Data class Domain;
Predictors PROSITE; PS51901; ACP_MB
Name Archaeal CBS proteins (ACP)-type metal binding (MB) domain
Function An archaeal family of CBS domain (see ) proteins that are able to function as electron transfer proteins contains a small (~35 amino acids) C-terminal metal-binding (MB) domain containing four cysteine residues arranged in a Cys-X(2)-Cys-X(14-19)-Cys-X(1-4)-Cys motif. The ACP-type MB domain can bind several metals, with iron and zinc being the most abundant metals.
Scope(s) Archaea
Euryarchaeota
Example(s) P50100 (Y525_METKA);

Propagated annotation [?]

Keywords [?]

case <FTGroup:1>
Metal-binding
Iron
Zinc
end case

Features [?]

From: PS51901
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="ACP-type MB #"
BINDING 6 6 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"		 C 1
BINDING 6 6 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C 1
BINDING 9 9 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"		 C 1
BINDING 9 9 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C 1
BINDING 25 25 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"		 C 1
BINDING 25 25 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C 1
BINDING 28 28 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"		 C 1
BINDING 28 28 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C 1

Additional information [?]

Size range 25-40 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

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UniProtKB rule member sequences [?]