Home  |  Contact
Entry: PS51912

General information about the entry

Entry name [info] DMAP1_BIND
Accession [info] PS51912
Entry type [info] MATRIX
Date [info] 22-APR-2020 CREATED;
22-APR-2020 DATA UPDATE;
10-FEB-2021 INFO UPDATE.
PROSITE Doc. [info] PDOC51912
Associated ProRule [info] PRU01260

Name and characterization of the entry

Description [info] DMAP1-binding domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=103;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=98;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3147242; R2=0.0054570; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1409; N_SCORE=10.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=767; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-24; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='N';  M= -31, -19,  50,  13, -70, -66, -26, -11, -57, -37, -60,  61,  26, -11, -64, -33,  13,  37, -89, -68;
/M: SY='Y';  M= -14, -22, -12, -28, -48, -73, -62,  31, -49,   5,  13, -67,  38, -19, -68,   7, -11,  15,  42,  65;
/M: SY='P';  M=  -7,  -4, -26, -26, -36, -49, -16, -48, -60,  -6, -62,  -7,  71, -57, -39,  66,   1, -25, -80, -67;
/M: SY='T';  M=  -2, -36, -15, -16, -24, -12, -13, -56,  12,  16, -55,  -4,  16, -57,  -5,  25,  46,   1, -79, -63;
/M: SY='L';  M= -40, -22, -82, -47, -43, -84, -69,   0, -76,  86, -30, -43, -83, -70, -75, -75, -62,  -9, -72, -55;
/M: SY='P';  M= -63, -86, -63, -55, -83, -65, -67, -73, -60, -82, -70,   0, 118, -63, -24,  12, -12, -76, -80, -80;
/M: SY='E';  M=   3, -76,  43,  68, -40, -51, -23, -68,  10,   0, -63, -13,  18, -30, -34, -15, -35, -30, -80, -36;
/M: SY='D';  M=  -8,  -9,  84,  57, -80, -14, -22, -52, -14, -77, -73,  -1, -64, -49, -32, -53,   3, -54, -88, -39;
/M: SY='V';  M=  -8, -68, -81, -76, -51, -50, -79,  37, -74,  34, -39, -76, -78, -73, -76, -45, -24,  76, -80, -60;
/M: SY='Q';  M= -62, -27, -60, -45, -77, -56, -52, -73,  19, -21, -59, -54, -71,  89,  82, -30, -38, -52, -74, -62;
/M: SY='E';  M=   1, -24,  -4,  53, -69, -31, -20,   0,  13,  10, -25,  -3, -67,  15,  22,   8, -38, -30, -78, -65;
/M: SY='K';  M=   8, -76, -55,  27, -77, -53, -25, -17,  62, -72, -63, -53, -30,  34,  54,  12, -57, -68, -75, -65;
/M: SY='W';  M= -41, -74, -86, -76, -25, -82, -73, -15, -48,  77, -36, -83, -41, -70, -40, -76, -66, -19, 104, -48;
/M: SY='Q';  M=  48, -72,  47, -46, -76, -38, -21, -71,   6, -41, -63,  15, -68,  62,   5,   5, -55, -46, -12, -20;
/M: SY='E';  M= -13,  -9,  16,  77, -39, -69,   6, -39,   9, -73, -67,  33, -63,  45,   0, -54, -40, -44, -81, -67;
/M: SY='L';  M=  -8, -69, -42, -72, -45, -81, -17, -34, -49,  82, -33, -77, -81, -68, -34, -71, -34,   9, -73, -55;
/M: SY='E';  M= -27, -79,  73,  79, -79, -70, -56,  -8, -17, -52, -70,  -2, -62, -23, -56, -56, -37, -70,  20, -69;
/M: SY='Q';  M= -62, -75, -18,  25, -59, -28, -58, -16, -39,  56, -45,   5, -72,  69,   0, -22, -60, -55, -75, -60;
/M: SY='E';  M=   6, -78,  44,  76, -79, -42, -55, -78,  31, -39, -68, -30, -35,  31, -13, -54, -59, -73, -79, -32;
/I:         I=-29; MD=-75;
/M: SY='L';  M= -71, -75, -85, -79,  -8, -88, -69, -31, -77,  76, -38, -83, -44, -73, -20, -41, -28, -31, -70,  24; D=-29;
/I:         I=-29; MI=0; MD=-75; IM=0; DM=-75;
/M: SY='Y';  M=  -5, -76, -63,  19, -36, -69, -60, -29,   4, -27, -25, -13, -74, -32, -17,  54, -25, -21, -69,  56; D=-29;
/I:         I=-29; DM=-75;
/M: SY='E';  M= -65, -81,  65,  70, -33, -43, -27, -35, -52, -37, -72,  29, -66,  -4, -28, -21, -35, -52, -88, -70; D=-29;
/I:         I=-29; DM=-75;
/M: SY='G';  M= -55, -10,  31,  37, -84,  84, -67, -90, -63, -85, -77, -51, -68, -22, -71, -53, -67, -84,  -3, -76; D=-29;
/I:         I=-29; DM=-75;
/M: SY='D';  M= -64,   5,  97,  -3, -73, -12, -57, -71, -59,  15, -67,  -9, -70, -21, -65,   3, -57, -71, -90, -26; D=-29;
/I:         I=-29; DM=-75;
/M: SY='I';  M= -64, -76, -85, -82, -48, -88, -81,  97, -78,  29,  -5, -76, -75, -73, -80, -36, -59, -14, -73, -56;
/M: SY='T';  M= -30, -61, -57, -60, -68, -67, -68, -59, -57, -64, -60, -47, -59, -61, -66,  -6, 113, -51, -88, -66;
/M: SY='Q';  M= -40, -81, -24,  61, -78, -71, -23, -34,  -9, -10, -29, -55, -11,  98, -19, -35, -60, -43, -76, -64;
/M: SY='K';  M= -62, -78, -54,  -6, -81, -70, -56, -79, 101, -77, -65, -48, -63,  55, -27, -55, -58, -75, -72, -65;
/M: SY='G';  M= -50, -77, -59,  18, -83,  99, -69, -90, -66, -85, -75, -51, -67, -62, -74, -50, -67, -83, -74, -77;
/M: SY='Y';  M= -71,  24, -71, -73,  44, -78,  38, -58, -67, -53, -51, -69, -82, -63, -64, -66, -30, -62, -34, 122;
/M: SY='N';  M= -40, -75,  29,  64, -73, -44, -54,  -1,   7, -31, -19,  70, -66, -23, -55, -55, -55,  -3,  -6, -68;
/M: SY='K';  M= -63, -75, -58, -46, -48, -71, -58, -67,  95,  16, -57,  -5, -67,   4,   1, -34, -39, -67, -73, -63;
/M: SY='K';  M= -58, -75, -54,  16, -75, -67, -57, -45,  83, -25, -15, -50, -64,  25,  11,  33, -12, -68, -75, -65;
/M: SY='K';  M= -65, -78, -62, -49, -68, -75, -57, -67,  78,  21, -56, -56, -70, -44,  75, -61, -61, -66, -73, -62;
/M: SY='A';  M=  42,  -5, -28, -57, -66, -51, -61, -40,  14,  21, -55,  -1, -70,  12,  35,  23,  13, -57, -76, -38;
/M: SY='K';  M=  38, -73, -13,  10, -44, -43, -25, -50,  50,  -9, -24, -13, -68,   3,  46,  -7, -57, -64,   7, -63;
/M: SY='L';  M= -67, -71, -85, -78, -42, -87, -71,  49, -78,  81,  -6, -82, -82, -71, -76, -76, -62, -34, -72, -54;
/M: SY='L';  M= -67, -70, -84, -78,  51, -85, -70,  20, -78,  75, -33, -80, -83, -74, -76, -74, -29,  -3, -65, -45;
/M: SY='E';  M=  33, -75,   4,  55, -28,   3,   7, -76,  -5, -50, -65, -54, -65,  32,  46, -14, -40, -69, -77, -65;
/M: SY='P';  M=  -5, -81,  28,  36, -83, -12, -62, -77,   6, -80, -71, -57,  89, -29,  -6,  10, -37, -75, -80, -75;
/M: SY='Y';  M=  28,  -8, -74, -73,  81, -72,  11, -39, -69, -51, -53, -33, -80, -69, -68, -42, -63, -57, -42,  92;
/M: SY='L';  M= -20, -73, -71, -26, -15,  36,  -9,  26, -15,  48,   2, -65, -74,  32, -66, -31, -61, -10, -73, -58;
/M: SY='P';  M= -43, -76, -64,  -9,  24, -12,   7, -31,  -2,  -6,  31, -25,  56,  29, -18,  -3,  -1, -20, -65,  38;
/M: SY='Q';  M=  29, -71, -24, -26, -28, -24,  -8, -25,  23,  27, -17,  22, -26,  33, -43,  -2, -13, -19, -73,  -1;
/M: SY='Q';  M=   3, -28,  31,  13, -41, -67,   2,  -7,  26, -20, -15, -38,  27,  52, -15,   3,  15, -48, -79, -64;
/I:         I=-7; MD=-19;
/M: SY='Q';  M=  -5, -85, -23, -33, -86, -57, -25, -77, -25, -19, -72,   8,  28,  44, -50, -11,  40, -48, -94, -79; D=-7;
/I:         I=-7; MD=-19;
/M: SY='Q';  M= -12, -33,   3, -35, -51,   3, -17, -81, -25, -60, -14,   6,  -6,  26, -41, -36,  -1,  -9, -98, -83; D=-7;
/I:         I=-7; MD=-19;
/M: SY='E';  M= -36, -99,  -8,   9, -98, -28, -26, -22,   8, -91, -86, -43, -91,   5, -50, -12,  -9, -12,-106, -91; D=-7;
/I:         I=-7; MI=0; MD=-19; IM=0; DM=-19;
/M: SY='K';  M= -30, -98, -80, -25,-101, -34, -84, -98,  19,-100, -92,   7,   8, -14, -28,   8,   1, -64,-104, -43; D=-7;
/I:         I=-7; DM=-19;
/M: SY='E';  M= -25, -96,  -1,  19,-100, -59, -10, -92, -28, -96, -89,   5,  14, -21, -34,  10, -14, -29,-106, -91; D=-7;
/I:         I=-7; DM=-19;
/M: SY='P';  M=  12, -89, -27, -23, -92, -24, -32, -40,  -5, -52, -80, -15,  21,  -8,  -7,   7,  11, -80, -97, -85; D=-7;
/I:         I=-7; DM=-19;
/M: SY='A';  M=  27, -71,   1,  23, -71, -65, -15, -14, -12, -63,  -3,  -9,   3,  22,  12,  21,  18,  25, -81, -66;
/M: SY='Q';  M= -13, -76,  -5, -16, -35,  -8,  33, -32,  37, -70, -62,  -5,  17,  58,  13,   9,  -8, -20,   8,   0;
/M: SY='R';  M= -32, -74,  14, -12, -67, -34, -14, -24,  27, -14, -59,  21, -11,  32,  35,  13,  18,  -4, -12,   0;
/M: SY='Q';  M= -16, -40,  -1,  39, -39, -69,  28, -50,   8, -48,  -1,   8,  -3,  59,  37, -15, -26, -27, -73,  18;
/M: SY='H';  M= -24, -73, -29,  -1, -64, -22,  38,  -3,   6,  21,  -9,  22, -20,  32,  22,  -8,   4,   1, -78, -36;
/M: SY='K';  M= -10, -16, -58,   7, -72,   8,  -4, -13,  34, -19, -60,   9,  17,  29,  22,  19,   0, -20, -78, -66;
/M: SY='S';  M=   3, -73,  36, -11, -75,  -7,   3, -14, -19, -46, -64,   8,   4,  19,  31,  39,  23, -51, -82, -66;
/M: SY='R';  M= -24, -74, -18, -42, -26, -32,   1, -22,  13,  24, -53,   6,  20, -55,  53,   5,   4,  -1,   7, -60;
/M: SY='E';  M= -18, -75,  34,  43, -74,   8, -26, -27, -12, -30,  -8,  12,  13,  22,   0,   6,   9, -18,  -9, -67;
/M: SY='T';  M=  11, -71, -13,  20, -72, -14,  32, -33,   8, -16, -60,   5,   4,  20, -15,  19,  47, -32, -81, -64;
/M: SY='E';  M= -12, -75,  29,  32, -77,  15, -13, -31,  31, -47, -65,  25, -66,  21,  27,   7, -11, -34, -80, -67;
/M: SY='L';  M= -27, -71,   2, -30,  25, -29,   9, -52, -24,  30,  -4, -36, -15, -31,  27,  28,  19,   7, -74, -55;
/M: SY='R';  M= -10, -77,  -1,  30,   7, -53,  51, -35,  32, -29, -28,  -6, -22,  21,  53, -34, -31, -32, -76, -57;
/M: SY='D';  M= -11,  36,  45,  17, -73, -48,  20, -72,  31, -39, -66,  17, -30, -51, -11,  37,  13, -33,  -4, -37;
/M: SY='E';  M= -59, -76,  28,  51, -32, -14,  26, -41, -12,   6, -36, -24, -41,   6,  27,  27, -12, -66, -77,  -2;
/M: SY='E';  M= -46, -77,  13,  63, -45, -55,  -3, -17,  17, -41, -64, -20, -65,  -8,  51,  20, -37, -30, -76,  -6;
/M: SY='H';  M= -22, -75, -59,  24,  -3, -71,  54,  15,  -6,  17, -51,  24, -22,  14, -27,  -4, -17, -35,  20,  39;
/M: SY='C';  M= -19,  52,  -5,  -8, -67, -66,  25, -25, -25, -18,   4,  19,  -3,  -8,  37,  34,  15, -11, -80,  -6;
/M: SY='E';  M= -13, -11, -32,  46, -74, -38,   8, -73,   5, -40, -16,  26,   8,   6,  24,  46,   8, -69, -80, -40;
/M: SY='D';  M= -21, -78,  56,  45, -76, -29,  -9, -27,  43, -37, -32,  -7,   4,  -1,   2, -13, -37, -52, -13, -34;
/M: SY='G';  M=  11,  13, -18,   5, -67,  30, -64,   2, -11, -27, -58, -13,   1,   0,  24, -19, -18,  25, -76,  -4;
/M: SY='H';  M= -20, -75, -17, -23,  -4, -48,  73, -42,  18, -15,   0,  21, -15,  -2, -10,  11, -58, -28, -63,  68;
/M: SY='T';  M= -18, -14, -40,  14, -12, -35, -19,  -2,  29,  11, -54, -31,   3,  10,  -1, -15,  50, -15, -76, -30;
/M: SY='E';  M=   8, -73,  -3,  53, -70, -65, -57, -28,   6, -26, -30,   5, -11,  30,  -5,  32, -11, -12, -76,   0;
/M: SY='K';  M=  29, -71, -34,  -1, -65, -35, -28, -18,  49,  21, -13,  -9, -21,  -9,   2,  -7, -27,   2, -76, -64;
/M: SY='V';  M= -18, -71, -15,  -6, -67, -22,  42, -49, -42, -30, -56,  -6,  15,   8,  -1,  40,   4,  51, -84, -63;
/M: SY='Q';  M= -36, -76,   1,  34, -42, -26, -12, -50,  43, -22, -29,   4, -66,  71,   2,  20, -32, -38, -77, -63;
/M: SY='A';  M=  44, -70,   0,  33, -74, -15, -61, -30,  -1, -23, -62,  10,   6,   4, -25,  29,  -5, -23, -79, -69;
/M: SY='A';  M=  29, -28, -17, -26, -28, -35, -65,  21, -60,  28,  -2, -22,  -8, -61,  25, -24, -35,  23, -72,  13;
/I:         I=-25; MD=-63;
/M: SY='Q';  M= -32, -83,  27, -17, -41, -41, -70,  -3,   4,  12, -64, -18, -44,  30, -23,  17, -14, -31, -88, -72; D=-25;
/I:         I=-25; MI=0; MD=-63; IM=0; DM=-63;
/M: SY='R';  M=   3, -72, -27, -28, -19, -40, -61, -37, -17,  44,  -8,   4, -21, -21,  53, -24, -14,   0, -73, -11;
/M: SY='L';  M=  18, -72, -26, -59, -63,   6,  14, -25,  23,  36, -51,   3,  20,  -9,   5, -24,   9, -43, -76, -33;
/M: SY='K';  M= -29, -76, -33,  23, -48, -13, -30, -34,  52, -37, -41,  26,  23,  43,  17,  -7,   1, -33, -77, -66;
/M: SY='H';  M=  -8, -29,   5,  22,  -8,   0,  46, -61,  -6, -36, -11, -39, -22,  23, -23,  31,   4,  13, -75,  10;
/M: SY='L';  M=  -2, -74, -45,  -9, -59, -38, -36,  15,  38,  41,   0, -51,  40, -23, -27, -62, -18,  -6,  -7, -34;
/M: SY='P';  M=  -5, -73,   3,  29, -67, -27,   4, -12,   2,  18,  -7, -34,  36, -26, -15,  36, -15, -17, -79, -65;
/M: SY='T';  M=  -2, -70, -57,  17, -33, -48,  -5, -28, -20, -15, -27,  16,  -9,   7,  30,  23,  48,  11, -80, -63;
/M: SY='Q';  M= -12,   0, -27,  27, -43, -32, -56, -52,  27, -17, -61,   9, -12,  59,  31,  23, -26, -38, -75, -14;
/M: SY='H';  M= -24, -73,  -8,  22, -68, -24,  69, -46, -26, -24,  54,  43, -31,  23, -11, -10,  17,   0, -84, -59;
/M: SY='P';  M=  10, -74, -12, -34, -77,  43,   4, -53, -29, -46, -66,  12,  53, -21,  16,  34, -10, -44, -80, -70;
/M: SY='I';  M= -18, -73,  24, -37, -40, -73, -67,  42, -36,  -1,  20, -23,  17,   6, -15,  -5,   6,  39, -79, -29;
/I:         I=-28; MD=-70;
/M: SY='P';  M= -29, -18, -24, -32, -45, -93, -91, -54, -21, -51, -23, -14,  12, -19, -33,   4, -27, -33,  -7, -92; D=-28;
/I:         I=-28; MI=0; MD=-70; IM=0; DM=-70;
/M: SY='P';  M=   5, -28,  -2, -19,  -2, -41,  30, -70,  -4, -55, -63,  42,  61,  37, -28,   6,   5, -51, -75,  12;
/M: SY='M';  M=   0, -73, -63, -27, -26,  17, -59, -31,  -3, -34,  54, -17,  11,  27,  40,  17,  10, -21, -73,  -3;
/M: SY='P';  M= -37, -23,  22,   8, -37, -67,  37, -65,  26, -21, -62,  21,  60,  -4,  11,   7, -24,   0, -82, -65;
/M: SY='S';  M=  13, -67,  27, -55, -70, -35, -23, -29, -59,  -2, -60,  -4,   4,  -4, -64,  65,  41, -32, -83, -66;
/M: SY='T';  M=  10, -69, -21, -41,  -2, -17, -27, -48,  42, -14, -59,  38,  -3, -26, -20, -18,  51,  -6, -77, -33;
/M: SY='E';  M= -40, -75, -40,  46, -43,  26, -60, -31,   5, -47, -66,  -9,  12, -22,  42,  36,  -1, -35, -78, -68;
/M: SY='R';  M= -27,  19,  -2,  26, -43, -24, -19, -10,   6, -26,  -7,  23, -68, -34,  45,  -8,  34,   7, -81, -64;
/M: SY='S';  M=  -2, -70,  -7, -10, -24, -27,   1, -35,  13, -31, -63,  21,  17,   2, -31,  65,   6, -21, -80, -64;
/M: SY='S';  M= -13, -70, -14,  13, -15,  -4,  20, -27, -26,   7, -56, -36,  -5,  -9, -13,  44,  32,   5, -18, -61;
/M: SY='N';  M= -28,   4, -39, -14, -24, -19, -12, -59,   1, -12,  -7,  52, -21,  27, -17,  50, -17,  12, -80, -31;
/I:         E1=0; IE=-380; DE=-380;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2021_01 which contains 564'277 sequence entries.


Total number of hits 20 in 20 different sequences
Number of true positive hits 20 in 20 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] DMAP1-binding
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
20 sequences

DI2BA_DANRE (Q6NVJ5    ), DIP2A_HUMAN (Q14689    ), DIP2A_MOUSE (Q8BWT5    ), 
DIP2B_HUMAN (Q9P265    ), DIP2B_MOUSE (Q3UH60    ), DIP2C_HUMAN (Q9Y2E4    ), 
DIP2_DROME  (Q9W0S9    ), DNMT1_BOVIN (Q24K09    ), DNMT1_CHICK (Q92072    ), 
DNMT1_HUMAN (P26358    ), DNMT1_MOUSE (P13864    ), DNMT1_PARLI (Q27746    ), 
DNMT1_RAT   (Q9Z330    ), GNPTA_DANRE (Q5RGJ8    ), GNPTA_HUMAN (Q3T906    ), 
GNPTA_MOUSE (Q69ZN6    ), GNPTG_BOVIN (Q58CS8    ), GNPTG_HUMAN (Q9UJJ9    ), 
GNPTG_MOUSE (Q6S5C2    ), YO093_YEAST (Q12275    )
» more


View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission