PROSITE entry PS51964
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General information about the entry
| Entry name [info] | SARS_ORF8_IG |
| Accession [info] | PS51964 |
| Entry type [info] | MATRIX |
| Date [info] |
29-SEP-2021 CREATED;
29-SEP-2021 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51964 |
| Associated ProRule [info] | PRU01309 |
Name and characterization of the entry
| Description [info] | SARS ORF8 accessory protein immunoglobulin (Ig)-like domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=103; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=98; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=4.3734336; R2=0.0076399; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=672; N_SCORE=9.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=279; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-64; D=-6; I=-6; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-15; ... A C D E F G H I K L M N P Q R S T V W Y /I: I=-150; B1=0; BI=-380; BD=-380; /M: SY='E'; M= -80, -99, -60, 77, -87, -99, -80, 42, -68, -75, -75, -80, -79, -62, -77, -80, -78, -67, -96, -86; D=-150; /I: I=-150; DM=-380; /M: SY='C'; M= -81, 122, -94, -89, -91, -95, -89, -98, -73, -89, -86, -82,-105, -86, 43, -81, -81, -87,-111, -94; D=-150; /I: I=-150; DM=-380; /M: SY='S'; M= -63, -81, -74, -76, -90, -73, -80, -86, -75, -90, -85, -63, -80, -71, -81, 72, 54, -78,-103, -84; D=-150; /I: I=-45; MI=0; MD=-115; IM=0; DM=-115; /M: SY='L'; M= -79, -87,-102, -95, -63,-104, -94, 32, -94, 44, -51, -97, -97, -91, -94, -90, -75, 40, -93, -74; D=-150; /I: I=-150; DM=-380; /M: SY='Q'; M= -76,-102, -71, -51,-107, -84, -64, -93, -57, -88, -74, -67, -84, 114, -57, -66, -79, -95, -89, -78; D=-150; /I: I=-150; DM=-380; /M: SY='S'; M= -70, -90, -69, 33, -90, -81, -28, -90, -59, -30, -81, -69, -83, -60, 48, 54, -67, -85, -96, -81; D=-150; /I: I=-150; DM=-380; /M: SY='C'; M= -78, 137, -98, -98, -88, -93, -98, -95, -94, -86, -86, -84,-109,-101,-100, -81, -78, -83,-118, -99; D=-150; /I: I=-150; DM=-380; /M: SY='C'; M= 28, 72, -82, -81, -86, -81, -88, -76, -80, -80, -77, -73, -84, -47, -86, -60, 64, -17,-103, -86; D=-150; /I: I=-150; DM=-380; /M: SY='Q'; M= -69, -93, -65, 34, -59, -79, -69, -93, -61, -90, -81, -66, -80, 82, -65, 43, -68, -90, -93, -80; D=-150; /I: I=-150; DM=-380; /M: SY='H'; M= -82, -90, -60, -72, -87, -76, 99, -31, -70, -89, -76, 79, -88, -66, -72, -68, -72, -92,-114, -68; D=-150; /I: I=-150; DM=-380; /M: SY='Q'; M= -75, -96, -71, -54,-101, -84, -67, -91, 31, -88, -76, -65, -81, 99, -54, -47, 4, -90, -90, -79; D=-150; /I: I=-150; DM=-380; /M: SY='P'; M= -81,-106, -81, -70,-101, -83, -84, -89, -77, -99, -85, -88, 113, -80, -90, -61, -73, -94, -94, -98; D=-150; /I: I=-150; DM=-380; /M: SY='Y'; M= -84, -95, -81, -83, 2, -90, 67, -76, -79, -71, -66, -78, -94, -73, -75, -27, -79, -80, -52, 104; D=-150; /I: I=-150; DM=-380; /M: SY='V'; M= -68, -84, -91, -80, -73, -95, -90, -19, -81, -58, -59, -86, -91, 44, -82, -77, -67, 79, -99, -76; D=-150; /I: I=-150; DM=-380; /M: SY='V'; M= -71, -81, -96, -89, -42, -97, -89, 16, -88, 36, 14, -92, -37, -86, -88, -83, -69, 60, -91, -70; D=-150; /I: I=-150; DM=-380; /M: SY='D'; M= -76, 15, 75, 69, -97, -82, -66, -97, -61, -92, -90, -41, -74, -56, -70, -68, -71, -91,-103, -85; D=-150; /I: I=-150; DM=-380; /M: SY='D'; M= -79, -91, 100, -47, -95, -75, -65, -92, -67, -38, -89, 25, -80, -67, -75, -67, -68, -91,-112, -81; D=-150; /I: I=-150; DM=-380; /M: SY='P'; M= -78,-103, -78, -67, -98, -80, -81, -86, -20, -96, -82, -84, 113, -77, -83, -71, -71, -91, -91, -94; D=-150; /I: I=-150; DM=-380; /M: SY='C'; M= -72, 137, -92, -92, -82, -88, -92, -24, -88, -79, -79, -79,-101, -94, -94, -25, -72, -74,-111, -92; D=-150; /I: I=-150; DM=-380; /M: SY='P'; M= -78,-101, -79, -67, -94, -81, -81, -83, -10, -38, -79, -84, 110, -76, -81, -74, -71, -88, -90, -92; D=-150; /I: MD=-15; DM=-380; /M: SY='I'; M= -27, -86, -90, -89, -68, -95, -93, 76, -84, -53, -55, -80, -84, -84, -47, -73, 39, -4, -91, -73; /I: MD=-15; DM=-380; /M: SY='H'; M= -77, -93, -71, -71, -83, 27, 116, -92, -74, -35, -69, -60, -84, 9, -71, -70, -81, -56,-104, -60; /I: MD=-15; DM=-380; /M: SY='Y'; M= -82, -86, -87, -86, 75, -89, 25, -62, -81, -25, 21, -81, -93, -80, -78, -47, -76, -67, -50, 85; /I: MD=-15; DM=-380; /M: SY='Y'; M= -81, 25, -82, -77, -46, -90, -57, -72, -72, -71, -66, -81, -94, 47, -28, -76, -78, -26, -53, 102; /I: MD=-15; DM=-380; /M: SY='S'; M= -62, -83, -74, -72, -87, -70, -76, -83, -74, -29, -80, -66, 50, -68, -79, 77, -10, -79, -95, -83; /I: MD=-15; DM=-380; /M: SY='K'; M= -77, -93, 41, 37, -96, -83, -69, -96, 66, -94, -85, -5, -77, -56, -26, -70, -72, -91, -94, -83; /I: MD=-15; DM=-380; /M: SY='W'; M= -87, 2,-111, -91, -58, -89,-109, -15, -85, -68, -82,-103, -93, -5, -87, -87, -96, -90, 156, -46; /I: MD=-15; DM=-380; /M: SY='Y'; M= -84, -89, -76, -83, 42, -85, -59, -71, -29, -23, -67, 50, -95, -76, -76, -76, -74, -76, -57, 88; /I: MI=0; MD=-15; IM=0; /M: SY='I'; M= -76, -89, -99, -97, -63,-103, -99, 84, -92, -25, -50, -91, -89, -90, -95, -86, -71, 28, -90, -71; /M: SY='R'; M= -81, -98, -76, -63, -93, -90, -68, -96, 26, -90, -79, -70, -88, 17, 89, -75, -79, -91, -90, -78; /M: SY='Y'; M= -76, -89, -93, -91, -55, -98, 1, 32, -87, -58, -59, -89, -94, -85, -87, -83, -72, 54, -73, 70; /M: SY='G'; M= -70, -91, -70, -85, -98, 70, -77,-103, -37,-102, -90, 56, -87, -77, -84, -65, -78, -99, -96, -93; /M: SY='T'; M= 50, -81, -80, -76, -85, -74, -82, -80, -77, -84, -78, -73, 12, -76, -83, -3, 51, -69, -92, -8; /M: SY='R'; M= -83, -99, -81, -69, -90, -94, -69, -51, -21, -87, -8, -73, -91, -57, 96, -78, -82, -88, -92, -78; /M: SY='K'; M= -75, -94, -76, -68, -98, 39, -80,-100, 73, -99, -87, -66, -83, -65, -54, -41, -78, -95, -91, -87; /M: SY='S'; M= -65, -83, -67, -75, -93, -39, -72, -92, -72, -96, -88, 57, -84, -68, -78, 72, -30, -87,-104, -86; /M: SY='A'; M= 63, -79, -82, -78, -40, -72, -86, -80, -79, -82, -78, -74, -82, -78, -84, -57, 51, -69, -95, -84; /M: SY='P'; M= -85,-104, -84, -77, -68, -90, -69, -86, -70, -87, -79, -36, 77, -75, 29, -81, -79, -90, -72, 69; /M: SY='L'; M= -78, -86, -87, -87, -68, -89, -81, -61, -87, 56, -57, 11, -96, -81, -88, 29, -72, -66, -94, -76; /I: MI=0; MD=-15; IM=0; /M: SY='I'; M= 35, -89, -98, -93, -76, -90, -98, 57, -92, -39, -63, -89, -92, -89, -95, -78, -74, 15, -96, -81; /M: SY='W'; M= -84,-107, -69, 57, -89, -94, -80,-100, -65, -94, -89, -82, -85, 45, 5, -81, -87, -98, 98, -74; /M: SY='L'; M= -88, -90,-105, -97, -61,-107, -89, -53, -99, 71, -49,-105,-105, -92, -96, -98, -84, -60, -92, -74; /M: SY='C'; M= -82, 133,-102,-102, -84, -98,-102, -99, -98, -90, -90, -88,-113,-106,-104, -85, -82, -87,-122,-103; /M: SY='V'; M= -14,-110,-109, -5,-103,-117,-117, -74,-107, -64, -90,-113,-114,-105,-112,-102, -95, 41,-126,-107; /M: SY='D'; M=-103,-122, 60, -84,-128, 16,-101,-130,-102,-127,-123, -81,-110,-100,-110, -96,-103,-126,-133,-115; /M: SY='E'; M= 35, -94, 8, 62,-101, -84, -80, -94, -71, -93, -89, -77, -82, -65, -79, -72, -78, -46,-102, -93; /M: SY='Y'; M= 38, -89, -38, -88, -66, -80, -81, -69, -89, 28, -65, -91, -96, -84, -90, -77, -79, -44, -81, 47; /M: SY='G'; M= -69, -96, -83, -44,-103, 82, -91,-111, -89,-106, -95, -71, -88, -86, -96, -70, -88,-104, -94, -98; /M: SY='K'; M= -42, -91, -76, -69, -92, -79, 11, -96, 56, -96, -86, -66, -84, -64, -21, 53, -67, -80, -98, -83; /M: SY='K'; M= -79, -94, -83, -32, -88, -96, -84, -68, 54, -80, -76, -78, -90, -67, 31, -80, -76, 38, -98, -83; /M: SY='S'; M= -72, -87, -89, -87, -74, -86, -86, -1, -87, 32, -64, -80, -90, -80, -89, 54, -46, -19, -97, -79; /M: SY='P'; M= -59,-106, -85, -74,-103, -84, -87, -92, -81, -88, -89, -88, 103, -83, -92, 0, -74, -95, -98,-100; /M: SY='I'; M= -85, -93,-104,-101, 58,-105, -97, 73, -96, -52, -57, -94, -95, -97, -98, -91, -78, -24, -77, -58; /M: SY='H'; M= -81,-100, -71, -59, -94, -86, 99, -97, -47, -86, -73, -63, -85, 86, -62, -70, -81, -98,-100, -45; /M: SY='Y'; M=-105,-115,-104,-107, -52,-111, -69, -90, -99, -87, -83,-105,-117, -94, -96, -99, -99, -95, -60, 101; /M: SY='I'; M= -95,-111, -96, 21, -87,-118,-106, 64, -97, -71, -74,-102,-100, -55,-103,-100, -91, -60,-107, -92; /M: SY='D'; M= -80, -93, 75, -56, -89, -83, -67, -85, -28, -79, 58, -60, -84, -63, 52, -74, -74, -85,-101, -77; /M: SY='W'; M= -84, -96,-105, -97, 37, -97,-100, 65, -91, -36, -60, -96, -92, -90, -93, -90, -81, -51, 113, -52; /M: SY='H'; M= -68, -91, -74, -82, -92, 74, 83,-103, -80, -94, -81, -62, -82, -74, -82, -65, -82, -97, -94, -75; /M: SY='N'; M= -73, -79, -55, -72, -88, -69, -63, -84, -64, -91, -81, 96, -82, -67, -73, -55, 51, -82,-108, -84; /M: SY='Y'; M= -82, -92, -88, -87, -40, -91, -55, -63, -80, -58, 81, -85, -93, -74, -77, -81, -78, -69, -51, 105; /M: SY='T'; M= -66, -77, -78, -79, -77, -85, -86, -57, -76, -69, -68, -68, -78, -79, -82, -19, 83, 40,-102, -78; /M: SY='Q'; M= -70, -87, -86, -73, -64, -93, -83, 23, -75, -58, 6, -81, -88, 66, -76, -75, -69, 60, -93, -73; /M: SY='S'; M= 2, -78, -71, -72, -82, -67, -73, -83, -71, -86, -80, -21, -78, -66, -76, 75, 33, -75, -92, -7; /M: SY='C'; M= -75, 139, -95, -95, -85, -91, -95, -92, -91, -83, -83, -81,-106, -99, -97, -78, -75, -80,-115, -96; /M: SY='T'; M= -71, -82, -71, 32, -73, -87, -78, -66, -74, 36, -62, -73, -81, -69, -79, 11, 51, -66, -93, -76; /M: SY='P'; M= -82,-108, -83, -71,-102, -84, -86, -90, -79, -99, -86, -89, 112, -82, -91, -79, -75, -95, -95, -99; /I: MI=0; MD=-15; IM=0; /M: SY='F'; M= -82, -86,-102, -96, 78,-100, -89, -23, -94, 9, -59, -94, -99, -98, -92, -88, -77, 36, -71, -50; /M: SY='T'; M= -70, -81, -66, 32, -86, -86, -81, -65, -70, -82, -78, -65, -74, -70, -79, -56, 88, -71,-102, -83; /M: SY='I'; M= -82, -95,-103,-101, -65,-107,-103, 92, -96, -48, -52, -93, -90, -92, -99, -90, -75, -35, -90, -73; /M: SY='N'; M= -78, -84, -52, -73, -93, -67, -60, -91, -65,-100, -87, 107, -90, -66, -73, -32, -63, -95,-113, -88; /M: SY='C'; M= -78, 136, -98, -98, -88, -94, -98, -95, -94, -86, -86, -84,-109,-102,-101, -81, -78, -83,-118, -99; /M: SY='Q'; M= -77,-103, -73, -52,-108, -86, -66, -94, -58, -89, -76, -68, -85, 113, -58, -67, -80, -96, -90, -79; /M: SY='E'; M= -1, -95, 55, 60,-101, -84, -73, -99, -67, -96, -92, -3, -80, -63, -76, -71, -33, -92,-106, -90; /M: SY='P'; M= -83,-108, -83, -72,-102, -85, -85, -90, -79,-100, -87, -90, 111, -83, -92, -80, -75, -95, -96,-100; /M: SY='K'; M= 8, -91, -79, -68, -91, -84, -82, -76, 61, -85, -78, -75, 47, -68, -60, -73, -72, 11, -93, -85; /M: SY='L'; M= -74, -87, -93, -93, -64, 38, -89, -56, -91, 43, -58, -86, -94, -87, -92, -81, -78, 25, -91, -78; /M: SY='G'; M= -65, -92, -81, -93, -99, 87, -87,-107, -86,-103, -92, -67, -85, -84, -93, -66, -85,-101, -90, -94; /M: SY='S'; M= 36, -82, -78, -76, -93, -69, -80, -89, -75, -92, -86, -68, -84, -70, -22, 70, -60, -80, -98, -86; /M: SY='L'; M= -86, -88,-103, -95, -59,-105, -87, -51, -97, 73, -47,-102,-103, -89, -94, -96, -82, -58, -90, -72; /M: SY='V'; M= -76, -90,-103, -99, -70,-106,-105, 59, -95, -54, -58, -96, -95, -95, -98, -88, -73, 60,-100, -78; /M: SY='V'; M= 35, -84, -97, -90, -80, -88, -99, -49, -89, -66, -67, -92, -94, -90, -92, -75, -70, 67,-103, -84; /M: SY='R'; M= -86,-103, -83, -71, -95, -96, -71,-102, -43, -94, -83, -76, -95, -59, 97, -80, -85, -96, -95, -82; /M: SY='C'; M= -81, 132,-101,-100, -88, -96,-101, -97, -96, -88, -89, -88,-111,-103,-102, -84, -81, -86, 30, -96; /M: SY='W'; M= -70, -93, -87, -84, -77, -77, -89, -90, -82, -43, -88, -77, -88, -75, -86, 68, -68, -90, 113, -67; /M: SY='Y'; M= -92, -96, -95, -95, 68, -99, 7, -73, -89, -67, -70, -91,-103, -89, -86, -87, -86, -78, -53, 89; /M: SY='Y'; M= -89, -97, 38, -80, 13, -96, -68, -72, -86, 14, -68, -82, -99, -83, -86, -86, -82, -77, -66, 79; /M: SY='H'; M= -84,-100, -66, 56, -73, -95, 74, -89, -72, -84, -78, -76, -86, -64, -75, -80, -83, -26, -84, 54; /M: SY='D'; M= -85,-101, 79, 42,-106, -88, -73,-105, -31,-101, -98, -61, -83, -21, -30, -76, -78,-100,-112, -90; /M: SY='F'; M= -83, -21, -97, -99, 81, 36, -88, -80, -94, -72, -78, -84, -98, -98, -95, -28, -85, -82, -71, -53; /M: SY='H'; M= -34, -89, -89, -85, -70, -93, 68, -31, -87, 39, 16, -82, -49, -79, -85, -10, -77, -5, -98, -69; D=-150; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='E'; M= 21, -92, -30, 74, -99, -85, -77, -95, -66, -92, -87, -75, -77, -53, -75, -69, 4, -85, -99, -91; D=-150; /I: I=-150; DM=-380; /M: SY='Y'; M= -91, -96, -91, -92, 59, -97, 46, -75, -87, -69, -69, -87,-101, -85, -84, -86, -85, -80, -56, 89; D=-150; /I: I=-150; DM=-380; /M: SY='H'; M= -88,-101, -75, -71, -89, -92, 112,-104, -62, -89, -76, -66, -91, -62, 52, -78, -86,-101,-111, -63; D=-150; /I: I=-150; DM=-380; /M: SY='D'; M= -87,-100, 100, -50,-107, -83, -72,-105, -74,-103,-103, -54, -86, -73, -82, -74, -76,-102,-122, -89; D=-150; /I: I=-150; DM=-380; /M: SY='V'; M= -74, -88,-103, -98, -72,-105,-105, 31, -95, -57, -60, -97, -97, -96, -97, -87, -71, 74,-104, -80; D=-150; /I: I=-150; DM=-380; /M: SY='R'; M= -87, -99, -86, -76, -58, -98, 34, -84, -54, 12, -71, -79, -96, -66, 80, -83, -85, -84, -95, -75; D=-150; /I: I=-150; DM=-380; /M: SY='V'; M= -71, -85,-102, -96, -73,-103,-105, -38, -94, -59, -62, -98, -98, -97, -95, -85, -70, 84,-108, -81; D=-150; /I: I=-150; DM=-380; /M: SY='V'; M= -73, -87, 4, -88, -75,-101,-100, -42, -92, -62, -64, -91, -97, -94, -94, -84, -70, 79,-109, -82; D=-150; /I: I=-150; DM=-380; /M: SY='L'; M= -87, -89,-104, -96, -57,-106, -88, -52, -98, 72, -48,-103,-104, -90, -95, -97, -83, -59, -91, -73; D=-150; /I: I=-150; DM=-380; /M: SY='D'; M= -85, -95, 82, -57, 7, -84, -74, -95, -76, -94, -94, 23, -88, -77, -83, -72, 6, -94,-108, -81; D=-150; /I: I=-150; DM=-380; /M: SY='F'; M= -94, -94, -98, -91, 88,-101, -87, -76, 27, -69, -76, -51,-101, -93, -78, -90, -86, -78, -69, -48; D=-150; /I: I=-150; DM=-380; /M: SY='I'; M= -87,-101, -96, -89, -79,-105, -93, 65, -1, -61, -66, -65, -95, -81, 37, -80, -82, -44, -96, -81; D=-150; /I: I=-150; E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 6 in 6 different sequences |
| Number of true positive hits | 6 in 6 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | SARS ORF8 Ig-like |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
6 sequences
NS8A_SARS (Q7TFA0), NS8B_SARS (Q80H93), NS8_BC279 (Q0Q469), NS8_BCHK3 (Q3LZX5), NS8_BCRP3 (Q3I5I8), NS8_SARS2 (P0DTC8)» more
|
| PDB [Detailed view] |
5 PDB
7F5F; 7JTL; 7JX6; 7MX9; 7XMN |