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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU01309


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU01309
General rule information [?]

Accession PRU01309
Dates 06-APR-2021 (Created)
12-APR-2021 (Last updated, Version 3)
Data class Domain;
Predictors PROSITE; PS51964; SARS_ORF8_IG
Name SARS ORF8 accessory protein immunoglobulin (Ig)-like domain
Function The SARS related (SARSr) ORF8 accessory protein is thought to exert important functions in modulating the host infected cell metabolism and antiviral immunity. The SARSr ORF8 contains an immunoglobulin (Ig)-like domain.
Scope(s) Viruses
Sarbecovirus
Example(s) P0DTC8;

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
Disulfide bond
end case

Features [?]

From: PS51964
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="SARS ORF8 Ig-like #"
case <FTGroup:1>
DISULFID 2 2 /note="Interchain" disulf C
end case
DISULFID 7 72 disulf C-x*-C 1
DISULFID 19 84 disulf C-x*-C 1
DISULFID 43 65 disulf C-x*-C

Additional information [?]

Size range 20-90 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]